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A Proton Nuclear Magnetic Resonance Metabonomics Approach for Biomarker Discovery in Nonalcoholic Fatty Liver Disease
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Administration of the potent PPARα agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice
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Prevalence of Hepatic Steatosis in An Urban Population in the United States: Impact of Ethnicity
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A Genomic and Proteomic Study of the Spectrum of Nonalcoholic Fatty Liver Disease *
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Insulin Resistance: A Metabolic Pathway to Chronic Liver Disease *
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Nonalcoholic Fatty Liver Disease: From Steatosis to Cirrhosis
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CCAAT/enhancing binding protein β deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet‐induced nonalcoholic steatohepatitis†
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Polymorphism in microsomal triglyceride transfer protein
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Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis
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HFE C282Y mutations are associated with advanced hepatic fibrosis in Caucasians with nonalcoholic steatohepatitis
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Noninvasive diagnosis and monitoring of nonalcoholic steatohepatitis
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Selection for acute liver failure: Have we got it right?
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The Restorative Effect of Taurine on Experimental Nonalcoholic Steatohepatitis
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Nonalcoholic steatohepatitis: An expanded clinical entity
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Metabolomic networks in plants: Transitions from pattern recognition to biological interpretation
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Metabonomics: NMR spectroscopy and pattern recognition analysis of body fluids and tissues for characterisation of xenobiotic toxicity and disease diagnosis
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Decreased plasma glutamate in early phases of septic shock with acute liver dysfunction is an independent predictor of survival
inferredcites →https://doi.org/10.1016/j.jhep.2003.09.020openalex-snapshot
The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance
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The use of metabolomics for the discovery of new biomarkers of effect
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Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity☆, ☆☆
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Randomised trial of glutamine-enriched enteral nutrition on infectious morbidity in patients with multiple trauma
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Prevalence of non-alcoholic fatty liver disease: population based study
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Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics
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Metabolite profiling: from diagnostics to systems biology
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AGA technical review on nonalcoholic fatty liver disease
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The Natural History of Nonalcoholic Fatty Liver Disease: A Population-Based Cohort Study
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Serotonin Mediates Oxidative Stress and Mitochondrial Toxicity in a Murine Model of Nonalcoholic Steatohepatitis
inferredcites →https://doi.org/10.1053/jhep.2002.34738openalex-snapshot
Serum leptin in NASH correlates with hepatic steatosis but not fibrosis: A manifestation of lipotoxicity?
inferredcites →https://doi.org/10.1053/jhep.2003.50229openalex-snapshot
Clinical and Histologic Spectrum of Nonalcoholic Fatty Liver Disease Associated With Normal Alt Values
inferredcites →https://doi.org/10.1053/jhep.2003.50290openalex-snapshot
Hepatic Gene Expression in Histologically Progressive Nonalcoholic Steatohepatitis
inferredcites →https://doi.org/10.1056/nejmra011775openalex-snapshot
Nonalcoholic Fatty Liver Disease
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A data integration methodology for systems biology
inferredcites →https://doi.org/10.1093/ajcn/77.1.250openalex-snapshot
Plasma taurine concentrations increase after enteral glutamine supplementation in trauma patients and stressed rats
inferredcites →https://doi.org/10.1093/alcalc/34.4.529openalex-snapshot
REVERSAL OF ETHANOL-INDUCED HEPATIC STEATOSIS AND LIPID PEROXIDATION BY TAURINE: A STUDY IN RATS
inferredcites →https://doi.org/10.1093/jjco/27.1.13openalex-snapshot
Measurement of lactate levels in serum and bile using proton nuclear magnetic resonance in patients with hepatobiliary diseases: its utility in detection of malignancies
inferredcites →https://doi.org/10.1093/jn/130.9.2222openalex-snapshot
The Relationship between Plasma Taurine and Other Amino Acid Levels in Human Sepsis
inferredcites →https://doi.org/10.1097/00075197-200401000-00011openalex-snapshot
Glutamine: recent developments in research on the clinical significance of glutamine
inferredcites →https://doi.org/10.1111/j.1440-1746.2007.04952.xopenalex-snapshot
What are the risk factors and settings for non‐alcoholic fatty liver disease in Asia–Pacific?
inferredcites →https://doi.org/10.1126/science.1104635openalex-snapshot
Systems Biology and New Technologies Enable Predictive and Preventative Medicine
inferredcites →https://doi.org/10.1136/gut.2005.071118openalex-snapshot
Tumour necrosis factor α signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in mice
inferredcites →https://doi.org/10.1186/1472-6947-7-35openalex-snapshot
A comparative analysis of predictive models of morbidity in intensive care unit after cardiac surgery – Part I: model planning
inferredcites →https://doi.org/10.1194/jlr.m600198-jlr200openalex-snapshot
Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1
inferredcites →https://doi.org/10.1210/jc.2006-0587openalex-snapshot
The Role of Insulin Resistance in Nonalcoholic Fatty Liver Disease
inferredcites →https://doi.org/10.1210/jc.2007-2161openalex-snapshot
Reduced Parietooccipital White Matter Glutamine Measured by Proton Magnetic Resonance Spectroscopy in Treated Graves’ Disease Patients
inferredcites →https://doi.org/10.2174/1568026023394498openalex-snapshot
Metabonomic Applications in Toxicity Screening and Disease Diagnosis
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Targeting Hepatic Glutaminase 1 Ameliorates Non-Alcoholic Steatohepatitis by Restoring Disrupted Hepatic Very-Low Density Lipoproteins Triglyceride Assembly
inferred← citeshttps://doi.org/10.1002/bmc.4795openalex-snapshot
Nontargeted urine metabolomics analysis of the protective and therapeutic effects of Citri Reticulatae Chachiensis Pericarpium on high‐fat feed‐induced hyperlipidemia in rats
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Metabonomics in Clinical Practice
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inferred← citeshttps://doi.org/10.1007/978-94-007-7742-2_42-1openalex-snapshot
Liver Transplantation Biomarkers in the Metabolomics Era
inferred← citeshttps://doi.org/10.1007/s00216-013-7254-xopenalex-snapshot
VIZR—an automated chemometric technique for metabolic profiling
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NMR-based metabolomics in human disease diagnosis: applications, limitations, and recommendations
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NMR-based metabonomic study of Chinese medicine Gegen Qinlian Decoction as an effective treatment for type 2 diabetes in rats
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Plasma and stool metabolomics to identify microbiota derived-biomarkers of metabolic dysfunction-associated fatty liver disease: effect of PNPLA3 genotype
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Nuclear magnetic resonance (NMR) spectroscopy in plant metabolite analysis: Applications in drug discovery
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Metabolomics-based search for therapeutic agents for non-alcoholic steatohepatitis
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Lactylation in metabolic dysfunction-associated steatotic liver disease: epigenetic regulatory mechanisms and potential therapeutic strategies
inferred← citeshttps://doi.org/10.1016/j.cgh.2016.05.046openalex-snapshot
Noninvasive Detection of Nonalcoholic Steatohepatitis Using Clinical Markers and Circulating Levels of Lipids and Metabolites
inferred← citeshttps://doi.org/10.1016/j.cmet.2020.01.013openalex-snapshot
Targeting Hepatic Glutaminase 1 Ameliorates Non-alcoholic Steatohepatitis by Restoring Very-Low-Density Lipoprotein Triglyceride Assembly
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TM6SF2/PNPLA3/MBOAT7 loss-of-function genetic variants impact on NAFLD development and progression both in patients and in in vitro models
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e27075openalex-snapshot
Integrative proteomics and metabolomics explore the effect and mechanism of Qiyin granules on improving nonalcoholic fatty liver disease
inferred← citeshttps://doi.org/10.1016/j.immuni.2019.10.014openalex-snapshot
Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function
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TM6SF2/PNPLA3/MBOAT7 Loss-of-Function Genetic Variants Impact on NAFLD Development and Progression Both in Patients and in In Vitro Models
inferred← citeshttps://doi.org/10.1016/j.jhep.2012.07.003openalex-snapshot
Phenotyping the effect of diet on non-alcoholic fatty liver disease
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The metabolomic window into hepatobiliary disease
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Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers
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Role of ammonia in NAFLD: An unusual suspect
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Pioneers: Navigating the Human Proteome for the Future of Precision Medicine
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Therapeutic potential of puerarin against methionine-choline-deficient diet-induced non-alcoholic steatohepatitis determined by combination of 1H NMR spectroscopy-based metabonomics and 16S rRNA gene sequencing
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Valoración de la enfermedad por hígado graso no alcohólico desde el laboratorio clínico
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The acidic pathway of bile acid synthesis: Not just an alternative pathway
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Strategies, models and biomarkers in experimental non-alcoholic fatty liver disease research
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Decreased hepatotoxic bile acid composition and altered synthesis in progressive human nonalcoholic fatty liver disease
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Transcriptomics and Metabolomics for Co-Exposure to a Cocktail of Neonicotinoids and the Synergist Piperonyl Butoxide
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Multichannel Nanogenerator-Driven Collaborative Metabolic Fingerprint Diagnostic Strategy for Early Screening and Risk Evaluation of Nonalcoholic Fatty Liver Disease
inferred← citeshttps://doi.org/10.1021/acs.jafc.5b02830openalex-snapshot
Mass-Spectrometry-Based Serum Metabolomics of a C57BL/6J Mouse Model of High-Fat-Diet-Induced Non-alcoholic Fatty Liver Disease Development
inferred← citeshttps://doi.org/10.1038/s41598-026-36704-xopenalex-snapshot
NMR metabolomic signatures of healthy lifestyle and incident MASLD
inferred← citeshttps://doi.org/10.1039/c5ra12224dopenalex-snapshot
Cholestatic liver injury model of bile duct ligation and the protection of Huang-Lian-Jie-Du decoction by NMR metabolomic profiling
inferred← citeshttps://doi.org/10.1039/d0ra06577copenalex-snapshot
Early detection of metabolic changes in drug-induced steatosis using metabolomics approaches
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Metabolic Phenotyping and Systems Biology Approaches to Understanding Metabolic Syndrome and Fatty Liver Disease
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Glutamate–oxaloacetate transaminase activity promotes palmitate lipotoxicity in rat hepatocytes by enhancing anaplerosis and citric acid cycle flux
inferred← citeshttps://doi.org/10.1097/mco.0000000000000706openalex-snapshot
Protein and amino acids in nonalcoholic fatty liver disease
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Ifnar1 signaling breaks the hepatic urea cycle to regulate adaptive immunity
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Clinical metabolomics paves the way towards future healthcare strategies
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Small metabolites, possible big changes: a microbiota-centered view of non-alcoholic fatty liver disease
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Impaired Ca2+ signaling due to hepatic steatosis mediates hepatic insulin resistance in Alström syndrome mice that is reversed by GLP-1 analog treatment
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Non-Alcoholic Steatohepatitis: New Insights from OMICS Studies
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The Role of the Transsulfuration Pathway in Non-Alcoholic Fatty Liver Disease
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Study of the Serum Metabolomic Profile in Nonalcoholic Fatty Liver Disease: Research and Clinical Perspectives
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Changes in human hepatic metabolism in steatosis and cirrhosis
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Urinary metabolomics analysis identifies key biomarkers of different stages of nonalcoholic fatty liver disease
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Metabonomic window into hepatitis B virus-related hepatic diseases
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