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Role for c-Abl tyrosine kinase in growth arrest response to DNA damage
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/0092-8674(91)90011-mopenalex-snapshot
Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene
inferredcites →https://doi.org/10.1016/0092-8674(93)90497-eopenalex-snapshot
A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle
inferredcites →https://doi.org/10.1016/0092-8674(93)90500-popenalex-snapshot
WAF1, a potential mediator of p53 tumor suppression
inferredcites →https://doi.org/10.1016/0092-8674(94)90240-2openalex-snapshot
The nuclear tyrosine kinase c-abl negatively regulates cell growth
inferredcites →https://doi.org/10.1016/0092-8674(94)90379-4openalex-snapshot
p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest
inferredcites →https://doi.org/10.1016/0092-8674(95)90039-xopenalex-snapshot
Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
inferredcites →https://doi.org/10.1021/bi00003a041openalex-snapshot
1-.beta.-D-Arabinofuranosylcytosine Activates Tyrosine Phosphorylation of p34cdc2 and Its Association with the SRC-like p56/p53lyn Kinase in Human Myeloid Leukemia Cells
inferredcites →https://doi.org/10.1038/366701a0openalex-snapshot
p21 is a universal inhibitor of cyclin kinases
inferredcites →https://doi.org/10.1038/366707a0openalex-snapshot
Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit
inferredcites →https://doi.org/10.1038/376785a0openalex-snapshot
Activation of the c-Abl tyrosine kinase in the stress response to DMA-damaging agents
inferredcites →https://doi.org/10.1038/377552a0openalex-snapshot
Radiation-induced cell cycle arrest compromised by p21 deficiency
inferredcites →https://doi.org/10.1073/pnas.91.6.2026openalex-snapshot
Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells.
inferredcites →https://doi.org/10.1091/mbc.6.4.387openalex-snapshot
Inhibition of cyclin-dependent kinases by p21.
inferredcites →https://doi.org/10.1101/gad.8.15.1739openalex-snapshot
Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential.
inferredcites →https://doi.org/10.1128/mcb.15.10.5542openalex-snapshot
Abrogation of Retinoblastoma Protein Function by c-Abl through Tyrosine Kinase-Dependent and -Independent Mechanisms
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4781335openalex-extracted
The Abl1 Tyrosine Kinase and p53 are Key Players in Doxorubicin-Induced Cardiomyopathy and Their Cell Death Signaling Differs in Atrial and Ventricular Cardiomyocytes
inferred← citeshttps://doi.org/10.1002/(sici)1096-9896(199901)187:1<112::aid-path250>3.0.co;2-3openalex-snapshot
The p53 pathway
inferred← citeshttps://doi.org/10.1002/(sici)1097-0215(19981123)78:5<642::aid-ijc19>3.0.co;2-3openalex-snapshot
A phosphatidylinositol 3-kinase inhibitor wortmannin induces radioresistant DNA synthesis and sensitizes cells to bleomycin and ionizing radiation
inferred← citeshttps://doi.org/10.1002/(sici)1098-2744(199809)23:1<1::aid-mc1>3.0.co;2-qopenalex-snapshot
Relaxed cell-cycle arrests and propagation of unrepaired chromosomal damage in cancer cell lines with wild-typep53
inferred← citeshttps://doi.org/10.1002/1097-0142(20010601)91:11<1964::aid-cncr1221>3.0.co;2-bopenalex-snapshot
Expression of apoptosis proteins in chronic myelogenous leukemia
inferred← citeshttps://doi.org/10.1002/2211-5463.13177openalex-snapshot
c‐Abl kinase regulates cell proliferation and ionizing radiation‐induced G2/M arrest via phosphorylation of FHL2
inferred← citeshttps://doi.org/10.1002/bies.950191011openalex-snapshot
Hypothesis: Ataxia‐telangiectasia: Is ATM a sensor of oxidative damage and stress?
inferred← citeshttps://doi.org/10.1007/978-1-4020-4896-8_19openalex-snapshot
ATM, a paradigm for a stress-responsive signal transducer in higher vertebrate cells
inferred← citeshttps://doi.org/10.1007/978-1-4614-6220-0_9openalex-snapshot
The c-Abl/YAP/p73 Apoptotic Module and the HIPPO Pathway
inferred← citeshttps://doi.org/10.1007/978-1-4615-0081-0_11openalex-snapshot
Mutated Tyrosine Kinases As Therapeutic Targets In Myeloid Leukemias
inferred← citeshttps://doi.org/10.1007/978-1-4615-5287-1_2openalex-snapshot
The role of p53 in apoptosis
inferred← citeshttps://doi.org/10.1007/978-1-4615-5287-1_4openalex-snapshot
Stress-responsive signal transduction: emerging concepts and biological significance
inferred← citeshttps://doi.org/10.1007/978-1-59259-125-1_5openalex-snapshot
Inactivation of Negative Growth Regulators During Neoplastic Transformation
inferred← citeshttps://doi.org/10.1007/978-1-59259-455-9_19openalex-snapshot
Cellular Responses to DNA Damage and Human Chromosome Instability Syndromes
inferred← citeshttps://doi.org/10.1007/978-1-59259-720-8_6openalex-snapshot
Involvement of c-Abl Tyrosine Kinase in Apoptotic Response to Anticancer Agents
inferred← citeshttps://doi.org/10.1007/978-2-8178-0929-8_7openalex-snapshot
Deregulation of Mitochondrial Apoptosis in Cancer
inferred← citeshttps://doi.org/10.1007/978-3-031-52860-6_5openalex-snapshot
Resistance to Endocrine Therapy in Breast Cancer
inferred← citeshttps://doi.org/10.1007/978-3-540-69184-6_8openalex-snapshot
The p53 Tumor Suppressor Gene: Structure, Function and Mechanism of Action
inferred← citeshttps://doi.org/10.1007/978-3-540-74264-7_15openalex-snapshot
Signal Transduction and Apoptosis Pathways as Therapeutic Targets
inferred← citeshttps://doi.org/10.1007/978-3-642-59358-1_19openalex-snapshot
Therapeutic Strategies that Overcome Resistance to Nucleoside Analogues: Dysregulating Checkpoint Response and Survival Pathways by UCN-01
inferred← citeshttps://doi.org/10.1007/bf00787230openalex-snapshot
Apoptosis by p53: mechanisms, regulation, and clinical implications
inferred← citeshttps://doi.org/10.1007/bf02882063openalex-snapshot
Mechanism of p53 downstream effectors p21 and Gadd45 in DNA damage surveillance
inferred← citeshttps://doi.org/10.1007/bf02981952openalex-snapshot
Mechanisms of Transformation by the BCR/ABL Oncogene
inferred← citeshttps://doi.org/10.1007/bf02981955openalex-snapshot
Molecular Biology of Chronic Myeloid Leukemia
inferred← citeshttps://doi.org/10.1007/bf03038295openalex-snapshot
X-Ray induced changes in immunostaining of proliferating cell nuclear antigen (PCNA) in V79 hamster fibroblasts
inferred← citeshttps://doi.org/10.1007/bf03401721openalex-snapshot
Transcription Abnormalities Potentiate Apoptosis of Normal Human Fibroblasts
inferred← citeshttps://doi.org/10.1007/s00280-013-2310-yopenalex-snapshot
A novel antitumor piperazine alkyl compound causes apoptosis by inducing RhoB expression via ROS-mediated c-Abl/p38 MAPK signaling
inferred← citeshttps://doi.org/10.1007/s12031-011-9588-1openalex-snapshot
c-Abl in Neurodegenerative Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-820499-3.00001-xopenalex-snapshot
Cancer biology and other disorders: beneficial role of camptothecin and novel derivatives
inferred← citeshttps://doi.org/10.1016/b978-1-4160-3431-5.00011-xopenalex-snapshot
Myeloid Leukemia, Myelodysplasia, and Myeloproliferative Disease in Children
inferred← citeshttps://doi.org/10.1016/b978-1-4557-5414-4.00051-6openalex-snapshot
10.1016/b978-1-4557-5414-4.00051-6
inferred← citeshttps://doi.org/10.1016/j.bbcan.2017.02.003openalex-snapshot
Biological determinants of radioresistance and their remediation in pancreatic cancer
inferred← citeshttps://doi.org/10.1016/j.bbrc.2005.03.152openalex-snapshot
C-Abl as a modulator of p53
inferred← citeshttps://doi.org/10.1016/j.bbrc.2015.11.122openalex-snapshot
Inhibition of cyclic AMP response element-directed transcription by decoy oligonucleotides enhances tumor-specific radiosensitivity
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.116615openalex-snapshot
Targeting the crosstalk between estrogen receptors and membrane growth factor receptors in breast cancer treatment: Advances and opportunities
inferred← citeshttps://doi.org/10.1016/j.cancergencyto.2004.06.014openalex-snapshot
Clonal evolution with inv(11)(p15q22) and NUP98/DDX10 fusion gene in imatinib-resistant chronic myelogenous leukemia
inferred← citeshttps://doi.org/10.1016/j.cellsig.2011.03.019openalex-snapshot
High glucose induces apoptosis in embryonic neural progenitor cells by a pathway involving protein PKCδ
inferred← citeshttps://doi.org/10.1016/j.cellsig.2013.10.005openalex-snapshot
c-ABL tyrosine kinase modulates p53-dependent p21 induction and ensuing cell fate decision in response to DNA damage
inferred← citeshttps://doi.org/10.1016/j.febslet.2011.05.013openalex-snapshot
Beyond ATM: The protein kinase landscape of the DNA damage response
inferred← citeshttps://doi.org/10.1016/j.molcel.2006.04.007openalex-snapshot
Interaction between c-Abl and Arg Tyrosine Kinases and Proteasome Subunit PSMA7 Regulates Proteasome Degradation
inferred← citeshttps://doi.org/10.1016/j.pneurobio.2021.102122openalex-snapshot
c-Abl regulates a synaptic plasticity-related transcriptional program involved in memory and learning
inferred← citeshttps://doi.org/10.1016/j.taap.2003.08.017openalex-snapshot
Mitochondrial dysfunction as an early event in the process of apoptosis induced by woodfordin I in human leukemia K562 cells
inferred← citeshttps://doi.org/10.1016/j.yexcr.2006.10.011openalex-snapshot
Consequences of Shb and c-Abl interactions for cell death in response to various stress stimuli
inferred← citeshttps://doi.org/10.1016/s0006-291x(02)02692-xopenalex-snapshot
Arg tyrosine kinase is involved in homologous recombinational DNA repair
inferred← citeshttps://doi.org/10.1016/s0006-2952(00)00434-2openalex-snapshot
Nuclear tyrosine phosphorylation: the beginning of a map
inferred← citeshttps://doi.org/10.1016/s0014-5793(01)02429-2openalex-snapshot
Analysis of trk A and p53 association
inferred← citeshttps://doi.org/10.1016/s0014-5793(98)00057-xopenalex-snapshot
The pag gene product, a physiological inhibitor of c‐abl tyrosine kinase, is overexpressed in cells entering S phase and by contact with agents inducing oxidative stress
inferred← citeshttps://doi.org/10.1016/s0014-5793(98)01003-5openalex-snapshot
Tyrosine phosphorylation of the TATA element modulatory factor by the FER nuclear tyrosine kinases
inferred← citeshttps://doi.org/10.1016/s0026-895x(24)12108-6openalex-snapshot
Inhibition of c-Abl with STI571 Attenuates Stress-Activated Protein Kinase Activation and Apoptosis in the Cellular Response to 1-β-d-Arabinofuranosylcytosine
inferred← citeshttps://doi.org/10.1016/s0065-230x(02)85003-5openalex-snapshot
The Abl family kinases: Mechanisms of regulation and signaling
inferred← citeshttps://doi.org/10.1016/s0065-230x(08)60764-2openalex-snapshot
p53 in Tumor Progression: Life, Death, and Everything
inferred← citeshttps://doi.org/10.1016/s0065-230x(08)60785-xopenalex-snapshot
p53 and Human Cancer: The First Ten Thousand Mutations
inferred← citeshttps://doi.org/10.1016/s0070-2153(04)59007-5openalex-snapshot
Death by Abl: A Matter of Location
inferred← citeshttps://doi.org/10.1016/s0092-8674(00)00010-6openalex-snapshot
Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage
inferred← citeshttps://doi.org/10.1016/s0145-2126(01)00180-1openalex-snapshot
Bcr/Abl, leukemogenesis, and genomic instability: a complex partnership
inferred← citeshttps://doi.org/10.1016/s0167-8140(98)00027-9openalex-snapshot
Radiosensitivity and oxidative signalling in ataxia telangiectasia: an update
inferred← citeshttps://doi.org/10.1016/s0304-3835(99)00243-8openalex-snapshot
Peroxiredoxin I expression in human thyroid tumors
inferred← citeshttps://doi.org/10.1016/s0304-419x(97)00019-xopenalex-snapshot
The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy
inferred← citeshttps://doi.org/10.1016/s0304-419x(97)00020-6openalex-snapshot
Functional role for the c-Abl protein tyrosine kinase in the cellular response to genotoxic stress
inferred← citeshttps://doi.org/10.1016/s0304-419x(97)00023-1openalex-snapshot
Signal transduction by wild-type and leukemogenic Abl proteins
inferred← citeshttps://doi.org/10.1016/s0360-3016(96)00598-6openalex-snapshot
Potential molecular targets for manipulating the radiation response
inferred← citeshttps://doi.org/10.1016/s0378-1119(01)00521-2openalex-snapshot
Isolation of hNap1BP which interacts with human Nap1 (NCKAP1) whose expression is down-regulated in Alzheimer's disease
inferred← citeshttps://doi.org/10.1016/s0896-6273(00)80646-7openalex-snapshot
Essential Roles for the Abl and Arg Tyrosine Kinases in Neurulation
inferred← citeshttps://doi.org/10.1016/s0898-6568(00)00107-8openalex-snapshot
The substrate specificity of the catalytic domain of Abl plays an important role in directing phosphorylation of the adaptor protein Crk
inferred← citeshttps://doi.org/10.1016/s0955-0674(98)80146-4openalex-snapshot
Cellular responses to DNA damage
inferred← citeshttps://doi.org/10.1016/s0959-437x(97)80108-6openalex-snapshot
p53; from inductive signal to cellular effect
inferred← citeshttps://doi.org/10.1016/s0959-8049(98)00414-6openalex-snapshot
Cellular responses to radiation and risk of breast cancer
inferred← citeshttps://doi.org/10.1016/s0960-9822(00)00483-8openalex-snapshot
Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase
inferred← citeshttps://doi.org/10.1016/s0960-9822(06)00406-4openalex-snapshot
Cell-cycle signaling: Atm displays its many talents
inferred← citeshttps://doi.org/10.1016/s0962-8924(99)01549-4openalex-snapshot
Cycling, stressed-out and nervous: cellular functions of c-Abl
inferred← citeshttps://doi.org/10.1016/s1054-3589(08)61068-6openalex-snapshot
Role of p53 in Apoptosis
inferred← citeshttps://doi.org/10.1016/s1097-2765(00)00138-6openalex-snapshot
Cytoskeletal Protein PSTPIP1 Directs the PEST-Type Protein Tyrosine Phosphatase to the c-Abl Kinase to Mediate Abl Dephosphorylation
inferred← citeshttps://doi.org/10.1016/s1155-1984(20)30007-8openalex-snapshot
10.1016/s1155-1984(20)30007-8
inferred← citeshttps://doi.org/10.1016/s1359-6101(96)00047-0openalex-snapshot
Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL
inferred← citeshttps://doi.org/10.1016/s1368-8375(99)00067-6openalex-snapshot
c-Abl expression in oral squamous cell carcinomas
inferred← citeshttps://doi.org/10.1016/s1383-5742(02)00069-8openalex-snapshot
Protein kinases and their involvement in the cellular responses to genotoxic stress
inferred← citeshttps://doi.org/10.1017/s1462399403006835openalex-snapshot
Molecular pathogenesis of chronic myeloid leukaemia
inferred← citeshttps://doi.org/10.1021/acs.analchem.3c02593openalex-snapshot
Single-Cell Plasmonic Immunosandwich Assay Reveals the Modulation of Nucleocytoplasmic Localization Fluctuation of ABL1 on Cell Migration
inferred← citeshttps://doi.org/10.1038/21704openalex-snapshot
p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage
inferred← citeshttps://doi.org/10.1038/21710openalex-snapshot
Erratum: p73 is a human p53-related protein that can induce apoptosis
inferred← citeshttps://doi.org/10.1038/384273a0openalex-snapshot
Three distinct signalling responses by murine fibroblasts to genotoxic stress
inferred← citeshttps://doi.org/10.1038/386732a0openalex-snapshot
Functional interaction between DNA-PK and c-Abl in response to DNA damage
inferred← citeshttps://doi.org/10.1038/387516a0openalex-snapshot
Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation
inferred← citeshttps://doi.org/10.1038/387520a0openalex-snapshot
Interaction between ATM protein and c-Abl in response to DNA damage
inferred← citeshttps://doi.org/10.1038/cdd.2014.182openalex-snapshot
c-Abl antagonizes the YAP oncogenic function
inferred← citeshttps://doi.org/10.1038/cddis.2009.21openalex-snapshot
c-Abl downregulates the slow phase of double-strand break repair
inferred← citeshttps://doi.org/10.1038/nm.3562openalex-snapshot
Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers
inferred← citeshttps://doi.org/10.1038/nrc3563openalex-snapshot
Role of ABL family kinases in cancer: from leukaemia to solid tumours
inferred← citeshttps://doi.org/10.1038/onc.2008.334openalex-snapshot
TTK/Mps1 controls nuclear targeting of c-Abl by 14-3-3-coupled phosphorylation in response to oxidative stress
inferred← citeshttps://doi.org/10.1038/onc.2009.513openalex-snapshot
c-Abl regulates estrogen receptor α transcription activity through its stabilization by phosphorylation
inferred← citeshttps://doi.org/10.1038/onc.2012.505openalex-snapshot
RETRACTED ARTICLE: Claudin-1 induces epithelial–mesenchymal transition through activation of the c-Abl-ERK signaling pathway in human liver cells
inferred← citeshttps://doi.org/10.1038/onc.2013.84openalex-snapshot
The Ron receptor tyrosine kinase activates c-Abl to promote cell proliferation through tyrosine phosphorylation of PCNA in breast cancer
inferred← citeshttps://doi.org/10.1038/s41408-023-00810-0openalex-snapshot
ABL1 kinase as a tumor suppressor in AML1-ETO and NUP98-PMX1 leukemias
inferred← citeshttps://doi.org/10.1038/s41467-018-04716-5openalex-snapshot
The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow
inferred← citeshttps://doi.org/10.1038/sj.cdd.4400625openalex-snapshot
Regulation and activation of p53 and its family members
inferred← citeshttps://doi.org/10.1038/sj.cdd.4400626openalex-snapshot
c-Abl: activation and nuclear targets
inferred← citeshttps://doi.org/10.1038/sj.cdd.4400874openalex-snapshot
ATM, a central controller of cellular responses to DNA damage
inferred← citeshttps://doi.org/10.1038/sj.emboj.7601263openalex-snapshot
MUC1 oncoprotein blocks nuclear targeting of c‐Abl in the apoptotic response to DNA damage
inferred← citeshttps://doi.org/10.1038/sj.leu.2402038openalex-snapshot
Growth advantage of chronic myeloid leukemia CFU-GM in vitro : survival to growth factor deprivation, possibly related to autocrine stimulation, is a more common feature than hypersensitivity to GM-CSF/IL3 and is efficiently counteracted by retinoids ± α-interferon
inferred← citeshttps://doi.org/10.1038/sj.onc.1202239openalex-snapshot
Dominant effects of the bcr-abl oncogene on Drosophila morphogenesis
inferred← citeshttps://doi.org/10.1038/sj.onc.1202423openalex-snapshot
Activation of c-Abl tyrosine kinase requires caspase activation and is not involved in JNK/SAPK activation during apoptosis of human monocytic leukemia U937 cells
inferred← citeshttps://doi.org/10.1038/sj.onc.1202479openalex-snapshot
The presence of the Rb c-box peptide in the cytoplasm inhibits p210bcr-abl transforming function
inferred← citeshttps://doi.org/10.1038/sj.onc.1202541openalex-snapshot
The ATM protein is required for sustained activation of NF-κB following DNA damage
inferred← citeshttps://doi.org/10.1038/sj.onc.1202823openalex-snapshot
Suppression of the poly(ADP-ribose) polymerase activity by DNA-dependent protein kinase in vitro
inferred← citeshttps://doi.org/10.1038/sj.onc.1202930openalex-snapshot
Function for p300 and not CBP in the apoptotic response to DNA damage
inferred← citeshttps://doi.org/10.1038/sj.onc.1202954openalex-snapshot
mdm2: a bridge over the two tumour suppressors, p53 and Rb
inferred← citeshttps://doi.org/10.1038/sj.onc.1203290openalex-snapshot
Inhibition of v-Abl transformation by p53 and p19ARF
inferred← citeshttps://doi.org/10.1038/sj.onc.1203619openalex-snapshot
c-abl is involved in the association of p53 and trk A
inferred← citeshttps://doi.org/10.1038/sj.onc.1203667openalex-snapshot
The c-Abl tyrosine kinase contributes to the transient activation of MAP kinase in cells plated on fibronectin
inferred← citeshttps://doi.org/10.1038/sj.onc.1203878openalex-snapshot
Regulation of cell death by the Abl tyrosine kinase
inferred← citeshttps://doi.org/10.1038/sj.onc.1205060openalex-snapshot
ATM function and telomere stability
inferred← citeshttps://doi.org/10.1038/sj.onc.1205317openalex-snapshot
Tyrosine kinase oncogenes in normal hematopoiesis and hematological disease
inferred← citeshttps://doi.org/10.1042/bj20120506openalex-snapshot
Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins
inferred← citeshttps://doi.org/10.1054/bjoc.2000.1440openalex-snapshot
Effect of c-Abl tyrosine kinase on the cellular response to paclitaxel-induced microtubule damage
inferred← citeshttps://doi.org/10.1073/pnas.1411086111openalex-snapshot
c-Abl tyrosine kinase promotes adipocyte differentiation by targeting PPAR-gamma 2
inferred← citeshttps://doi.org/10.1073/pnas.94.15.8144openalex-snapshot
Thymineless death in colon carcinoma cells is mediated via Fas signaling
inferred← citeshttps://doi.org/10.1073/pnas.94.4.1437openalex-snapshot
Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase
inferred← citeshttps://doi.org/10.1073/pnas.96.24.13819openalex-snapshot
c-Abl-induced apoptosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activation
inferred← citeshttps://doi.org/10.1073/pnas.97.10.5486openalex-snapshot
c-Abl is required for development and optimal cell proliferation in the context of p53 deficiency
inferred← citeshttps://doi.org/10.1074/jbc.271.43.26457openalex-snapshot
Genotoxic Drugs Induce Interaction of the c-Abl Tyrosine Kinase and the Tumor Suppressor Protein p53
inferred← citeshttps://doi.org/10.1074/jbc.272.22.14005openalex-snapshot
Finkel-Biskis-Reilly Mouse Osteosarcoma Virus v-fos Inhibits the Cellular Response to Ionizing Radiation in a Myristoylation-dependent Manner
inferred← citeshttps://doi.org/10.1074/jbc.272.22.14320openalex-snapshot
Differential Signaling after β1 Integrin Ligation Is Mediated Through Binding of CRKL to p120 and p110
inferred← citeshttps://doi.org/10.1074/jbc.272.38.23485openalex-snapshot
Inhibition of Phosphatidylinositol 3-Kinase by c-Abl in the Genotoxic Stress Response
inferred← citeshttps://doi.org/10.1074/jbc.273.40.25654openalex-snapshot
Regulation of DNA-dependent Protein Kinase by the Lyn Tyrosine Kinase
inferred← citeshttps://doi.org/10.1074/jbc.273.7.3799openalex-snapshot
Regulation of Rad51 Function by c-Abl in Response to DNA Damage
inferred← citeshttps://doi.org/10.1074/jbc.274.13.8371openalex-snapshot
c-Abl Neutralizes the Inhibitory Effect of Mdm2 on p53
inferred← citeshttps://doi.org/10.1074/jbc.274.18.12748openalex-snapshot
Radiation-induced Assembly of Rad51 and Rad52 Recombination Complex Requires ATM and c-Abl
inferred← citeshttps://doi.org/10.1074/jbc.274.49.34663openalex-snapshot
Functional Interaction between SHPTP1 and the Lyn Tyrosine Kinase in the Apoptotic Response to DNA Damage
inferred← citeshttps://doi.org/10.1074/jbc.274.5.2732openalex-snapshot
Mitogen-activated Protein Kinase Kinase 2 Activation Is Essential for Progression through the G2/M Checkpoint Arrest in Cells Exposed to Ionizing Radiation
inferred← citeshttps://doi.org/10.1074/jbc.275.15.10779openalex-snapshot
Regulation of the Rapamycin and FKBP-Target 1/Mammalian Target of Rapamycin and Cap-dependent Initiation of Translation by the c-Abl Protein-tyrosine Kinase
inferred← citeshttps://doi.org/10.1074/jbc.275.2.725openalex-snapshot
c-Abl Tyrosine Kinase Is Not Essential for Ataxia Telangiectasia Mutated Functions in Chromosomal Maintenance
inferred← citeshttps://doi.org/10.1074/jbc.c000099200openalex-snapshot
Activation of the Cytoplasmic c-Abl Tyrosine Kinase by Reactive Oxygen Species
inferred← citeshttps://doi.org/10.1074/jbc.c100050200openalex-snapshot
The ARG Tyrosine Kinase Interacts with Siva-1 in the Apoptotic Response to Oxidative Stress
inferred← citeshttps://doi.org/10.1074/jbc.m007294200openalex-snapshot
Interaction of Hematopoietic Progenitor Kinase 1 and c-Abl Tyrosine Kinase in Response to Genotoxic Stress
inferred← citeshttps://doi.org/10.1074/jbc.m101414200openalex-snapshot
Targeting of the c-Abl Tyrosine Kinase to Mitochondria in the Necrotic Cell Death Response to Oxidative Stress
inferred← citeshttps://doi.org/10.1074/jbc.m111123200openalex-snapshot
H2O2 Induces a Transient Multi-phase Cell Cycle Arrest in Mouse Fibroblasts through Modulating Cyclin D and p21Cip1 Expression
inferred← citeshttps://doi.org/10.1074/jbc.m211327200openalex-snapshot
Role of SHP-2 Tyrosine Phosphatase in the DNA Damage-induced Cell Death Response
inferred← citeshttps://doi.org/10.1074/jbc.m300058200openalex-snapshot
Functional Interaction between the c-Abl and Arg Protein-tyrosine Kinases in the Oxidative Stress Response
inferred← citeshttps://doi.org/10.1074/jbc.m404396200openalex-snapshot
Phosphorylation of DNA Topoisomerase I by the c-Abl Tyrosine Kinase Confers Camptothecin Sensitivity
inferred← citeshttps://doi.org/10.1074/jbc.m409522200openalex-snapshot
Insights into Selective Activation of p53 DNA Binding by c-Abl
inferred← citeshttps://doi.org/10.1074/jbc.m506768200openalex-snapshot
SHP-2 Phosphatase Regulates DNA Damage-induced Apoptosis and G2/M Arrest in Catalytically Dependent and Independent Manners, Respectively
inferred← citeshttps://doi.org/10.1080/02648725.2000.10647992openalex-snapshot
The p53 Tumour Suppressor Protein
inferred← citeshttps://doi.org/10.1080/07357909909011718openalex-snapshot
The Molecular and Cellular Basis of Radiosensitivity: Implications for Understanding How Normal Tissues and Tumors Respond to Therapeutic Radiation
inferred← citeshttps://doi.org/10.1080/09553000400017408openalex-snapshot
Involvment of c‐abl in the radiation‐induced inhibition of myoblast differentiation
inferred← citeshttps://doi.org/10.1080/095530098142185openalex-snapshot
What has the cloning of the ATM gene told us about ataxia telangiectasia?
inferred← citeshttps://doi.org/10.1093/annonc/mds240openalex-snapshot
Enhanced expression of the PDGFR/Abl signaling pathway in aromatase inhibitor-resistant breast cancer
inferred← citeshttps://doi.org/10.1093/carcin/19.7.1173openalex-snapshot
Attenuation of G1 checkpoint function by the non-genotoxic carcinogen phenobarbital
inferred← citeshttps://doi.org/10.1093/carcin/23.4.541openalex-snapshot
p53-Mdm2--the affair that never ends
inferred← citeshttps://doi.org/10.1093/emboj/17.2.544openalex-snapshot
p53 binds and represses the HBV enhancer: an adjacent enhancer element can reverse the transcription effect of p53
inferred← citeshttps://doi.org/10.1093/emboj/21.4.514openalex-snapshot
c‐Abl is an effector of Src for growth factor‐induced c‐myc expression and DNA synthesis
inferred← citeshttps://doi.org/10.1093/emboj/cdf384openalex-snapshot
Tyrosine phosphorylation of Mdm2 by c‐Abl: implications for p53 regulation
inferred← citeshttps://doi.org/10.1093/intimm/11.9.1371openalex-snapshot
Protein tyrosine kinase Lyn mediates apoptosis induced by topoisomerase II inhibitors in DT40 cells
inferred← citeshttps://doi.org/10.1093/intimm/dxl143openalex-snapshot
Impaired V(D)J recombination and increased apoptosis among B cell precursors in the bone marrow of c-Abl-deficient mice
inferred← citeshttps://doi.org/10.1093/intimm/dxp027openalex-snapshot
The effects of c-Abl mutation on developing B cell differentiation and survival
inferred← citeshttps://doi.org/10.1093/jb/mvm068openalex-snapshot
c-Abl Tyrosine Kinase Activates p21 Transcription Via Interaction with p53
inferred← citeshttps://doi.org/10.1093/jpp/rgae131openalex-snapshot
The regulatory effects of mitragynine on P-glycoprotein transporter
inferred← citeshttps://doi.org/10.1096/fj.04-2226fjeopenalex-snapshot
Ablation of either p21 or Bax prevents p53‐dependent apoptosis induced by green tea polyphenol epigallocatechin‐3‐gallate
inferred← citeshttps://doi.org/10.1096/fj.202402159ropenalex-snapshot
c‐Abl Kinase Targets Tight Junction Protein ZO ‐2 in Regulation of Cell Migration and Morphology
inferred← citeshttps://doi.org/10.1101/gad.11.19.2456openalex-snapshot
The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity
inferred← citeshttps://doi.org/10.1101/gad.13.18.2400openalex-snapshot
c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF
inferred← citeshttps://doi.org/10.1111/j.1471-4159.2008.05533.xopenalex-snapshot
c‐Abl is involved in high glucose‐induced apoptosis in embryonic E12.5 cortical neural progenitor cells from the mouse brain
inferred← citeshttps://doi.org/10.1111/j.1749-6632.2002.tb04122.xopenalex-snapshot
From Genes to Therapy: The Case of Philadelphia Chromosome‐Positive Leukemias
inferred← citeshttps://doi.org/10.1111/j.1872-034x.2007.00068.xopenalex-snapshot
Fusion protein containing SH3 domain of c‐Abl induces hepatocarcinoma cells to apoptosis
inferred← citeshttps://doi.org/10.1124/mol.62.3.680openalex-snapshot
Inhibition of Cyclin-Dependent Kinase 2 by the Chk1-Cdc25A Pathway during the S-Phase Checkpoint Activated by Fludarabine: Dysregulation by 7-Hydroxystaurosporine
inferred← citeshttps://doi.org/10.1124/mol.63.2.276openalex-snapshot
Abrogation of the Cell Death Response to Oxidative Stress by the c-Abl Tyrosine Kinase Inhibitor STI571
inferred← citeshttps://doi.org/10.1128/.61.1.33-46.1997openalex-snapshot
Kinase cascades regulating entry into apoptosis
inferred← citeshttps://doi.org/10.1128/mcb.19.4.2986openalex-snapshot
Role for Caspase-Mediated Cleavage of Rad51 in Induction of Apoptosis by DNA Damage
inferred← citeshttps://doi.org/10.1128/mcb.20.14.4979-4989.2000openalex-snapshot
Activation of MEK Kinase 1 by the c-Abl Protein Tyrosine Kinase in Response to DNA Damage
inferred← citeshttps://doi.org/10.1128/mcb.20.15.5370-5380.2000openalex-snapshot
Role for Lyn Tyrosine Kinase as a Regulator of Stress-Activated Protein Kinase Activity in Response to DNA Damage
inferred← citeshttps://doi.org/10.1128/mcb.20.3.741-748.2000openalex-snapshot
Stimulation of p53 DNA Binding by c-Abl Requires the p53 C Terminus and Tetramerization
inferred← citeshttps://doi.org/10.1128/mcb.21.17.5869-5878.2001openalex-snapshot
c-Abl Regulates p53 Levels under Normal and Stress Conditions by Preventing Its Nuclear Export and Ubiquitination
inferred← citeshttps://doi.org/10.1128/mcb.21.18.6233-6242.2001openalex-snapshot
Targeting of the c-Abl Tyrosine Kinase to Mitochondria in Endoplasmic Reticulum Stress-Induced Apoptosis
inferred← citeshttps://doi.org/10.1128/mcb.22.10.3292-3300.2002openalex-snapshot
c-Abl Tyrosine Kinase Regulates the Human Rad9 Checkpoint Protein in Response to DNA Damage
inferred← citeshttps://doi.org/10.1134/s2079086418020068openalex-snapshot
Regulation of Telomerase Activity
inferred← citeshttps://doi.org/10.1146/annurev.genet.31.1.635openalex-snapshot
ATAXIA-TELANGIECTASIA AND THE NIJMEGEN BREAKAGE SYNDROME: Related Disorders But Genes Apart
inferred← citeshttps://doi.org/10.1155/2010/283863openalex-snapshot
p73-Binding Partners and Their Functional Significance
inferred← citeshttps://doi.org/10.1177/1947601912458586openalex-snapshot
Activation of Abl Family Kinases in Solid Tumors
inferred← citeshttps://doi.org/10.1182/blood-2006-04-019141openalex-snapshot
SHP-2 phosphatase is required for hematopoietic cell transformation by Bcr-Abl
inferred← citeshttps://doi.org/10.1182/blood-2015-11-681171openalex-snapshot
Normal ABL1 is a tumor suppressor and therapeutic target in human and mouse leukemias expressing oncogenic ABL1 kinases
inferred← citeshttps://doi.org/10.1182/blood.v89.6.1845openalex-snapshot
Apoptosis and the Dilemma of Cancer Chemotherapy
inferred← citeshttps://doi.org/10.1182/blood.v92.3.981openalex-snapshot
Fas-Mediated Modulation of Bcr/Abl in Chronic Myelogenous Leukemia Results in Differential Effects on Apoptosis
inferred← citeshttps://doi.org/10.1182/blood.v96.9.3294openalex-snapshot
The ABL kinase inhibitor STI571 does not affect survival of hematopoietic cells after ionizing radiation
inferred← citeshttps://doi.org/10.1186/1476-4598-10-88openalex-snapshot
Tip60-mediated acetylation activates transcription independent apoptotic activity of Abl
inferred← citeshttps://doi.org/10.1186/bcr3191openalex-snapshot
Preclinical and clinical studies of estrogen deprivation support the PDGF/Abl pathway as a novel therapeutic target for overcoming endocrine resistance in breast cancer
inferred← citeshttps://doi.org/10.1186/s12967-024-05623-8openalex-snapshot
The Abl1 tyrosine kinase is a key player in doxorubicin-induced cardiomyopathy and its p53/p73 cell death mediated signaling differs in atrial and ventricular cardiomyocytes
inferred← citeshttps://doi.org/10.1196/annals.1322.050openalex-snapshot
Rational Approaches to the Design of Therapeutics Targeting Molecular Markers: The Case of Chronic Myelogenous Leukemia
inferred← citeshttps://doi.org/10.1201/b18597-4openalex-snapshot
Elucidation of Proto-Oncogene C-Abl Function with the Use of Mouse Models and the Disease Model of Chronic Myeloid Leukemia
inferred← citeshttps://doi.org/10.12659/msm.904888openalex-snapshot
Global Regulation of Differential Gene Expression by c-Abl/Arg Oncogenic Kinases
inferred← citeshttps://doi.org/10.1289/ehp.8026openalex-snapshot
Profiles of Global Gene Expression in Ionizing-Radiation–Damaged Human Diploid Fibroblasts Reveal Synchronization behind the G1 Checkpoint in a G0-like State of Quiescence
inferred← citeshttps://doi.org/10.1517/14728222.8.3.221openalex-snapshot
Targeting mutated tyrosine kinases in the therapy of myeloid leukaemias
inferred← citeshttps://doi.org/10.1667/0033-7587(2000)153[0245:stacrr]2.0.co;2openalex-snapshot
Signal Transduction and Cellular Radiation Responses
inferred← citeshttps://doi.org/10.18632/oncotarget.13882openalex-snapshot
Opposing roles of KIT and ABL1 in the therapeutic response of gastrointestinal stromal tumor (GIST) cells to imatinib mesylate
inferred← citeshttps://doi.org/10.21037/tcr.2016.11.75openalex-snapshot
Regulation of the Mdm2-p53 signaling axis in the DNA damage response and tumorigenesis
inferred← citeshttps://doi.org/10.2165/00003495-200059030-00004openalex-snapshot
Kinase Inhibitors in Cancer Therapy
inferred← citeshttps://doi.org/10.2307/3579567openalex-snapshot
Differential Activation of p53 Targets in Cells Treated with Ultraviolet Radiation That Undergo Both Apoptosis and Growth Arrest
inferred← citeshttps://doi.org/10.3109/10428190009053535openalex-snapshot
p27 in Cell Cycle Control and Cancer
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