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The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes

https://doi.org/10.1038/ng.493
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/gepi.20032openalex-snapshot
Use of unphased multilocus genotype data in indirect association studies
inferredcites →https://doi.org/10.1007/bf02473268openalex-snapshot
FA1 immunoreactivity in endocrine tumours and during development of the human fetal pancreas; negative correlation with glucagon expression
inferredcites →https://doi.org/10.1016/j.ajhg.2009.01.005openalex-snapshot
A Unified Approach to Genotype Imputation and Haplotype-Phase Inference for Large Data Sets of Trios and Unrelated Individuals
inferredcites →https://doi.org/10.1016/s0168-9525(02)00004-5openalex-snapshot
H19 and Igf2 – enhancing the confusion?
inferredcites →https://doi.org/10.1038/ejhg.2009.19openalex-snapshot
Segregation analysis in a family at risk for the Maroteaux–Lamy syndrome conclusively reveals c.1151G>A (p.S384N) as to be a polymorphism
inferredcites →https://doi.org/10.1038/ejhg.2009.195openalex-snapshot
A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis
inferredcites →https://doi.org/10.1038/nature05911openalex-snapshot
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
inferredcites →https://doi.org/10.1038/nature07631openalex-snapshot
Progress and challenges in genome-wide association studies in humans
inferredcites →https://doi.org/10.1038/ng.2007.17openalex-snapshot
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
inferredcites →https://doi.org/10.1038/ng.249openalex-snapshot
Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci
inferredcites →https://doi.org/10.1038/ng.381openalex-snapshot
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
inferredcites →https://doi.org/10.1038/ng.412openalex-snapshot
New common variants affecting susceptibility to basal cell carcinoma
inferredcites →https://doi.org/10.1038/ng1197-350openalex-snapshot
Insulin VNTR allele-specific effect in type 1 diabetes depends on identity of untransmitted paternal allele
inferredcites →https://doi.org/10.1038/ng1233openalex-snapshot
Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12
inferredcites →https://doi.org/10.1038/ng2088openalex-snapshot
A new multipoint method for genome-wide association studies by imputation of genotypes
inferredcites →https://doi.org/10.1038/scientificamerican0108-42aopenalex-snapshot
The Wellcome Trust Case Control Consortium, U.K.
inferredcites →https://doi.org/10.1038/sj.leu.2403832openalex-snapshot
Dlk1 in normal and abnormal hematopoiesis
inferredcites →https://doi.org/10.1074/jbc.m607530200openalex-snapshot
dlk1/FA1 Regulates the Function of Human Bone Marrow Mesenchymal Stem Cells by Modulating Gene Expression of Pro-inflammatory Cytokines and Immune Response-related Factors
inferredcites →https://doi.org/10.1080/01621459.1963.10500879openalex-snapshot
Chi-Square Tests with One Degree of Freedom; Extensions of the Mantel- Haenszel Procedure
inferredcites →https://doi.org/10.1086/301802openalex-snapshot
A Log-Linear Approach to Case-Parent–Triad Data: Assessing Effects of Disease Genes That Act Either Directly or through Maternal Effects and That May Be Subject to Parental Imprinting
inferredcites →https://doi.org/10.1086/302466openalex-snapshot
Methods for Detection of Parent-of-Origin Effects in Genetic Studies of Case-Parents Triads
inferredcites →https://doi.org/10.1086/429843openalex-snapshot
Localization of a Type 1 Diabetes Locus in the IL2RA/CD25 Region by Use of Tag Single-Nucleotide Polymorphisms
inferredcites →https://doi.org/10.1089/scd.2007.0102openalex-snapshot
Dlk1 Influences Differentiation and Function of β Lymphocytes
inferredcites →https://doi.org/10.1093/biostatistics/kxn007openalex-snapshot
Testing for association on the X chromosome
inferredcites →https://doi.org/10.1111/j.1432-1033.1994.00083.xopenalex-snapshot
Protein Structure of Fetal Antigen 1 (FA1)
inferredcites →https://doi.org/10.1159/000073729openalex-snapshot
Detecting Disease Associations due to Linkage Disequilibrium Using Haplotype Tags: A Class of Tests and the Determinants of Statistical Power
inferredcites →https://doi.org/10.1159/000101422openalex-snapshot
An R Package for Analysis of Whole-Genome Association Studies
inferredcites →https://doi.org/10.1186/1471-2156-7-44openalex-snapshot
Loss of imprinting at the Dlk1-Gtl2 locus caused by insertional mutagenesis in the Gtl2 5' region
inferredcites →https://doi.org/10.1186/ar2698openalex-snapshot
Replication of recently identified systemic lupus erythematosus genetic associations: a case–control study
inferredcites →https://doi.org/10.1186/gb-2004-5-10-r80openalex-snapshot
Bioconductor: open software development for computational biology and bioinformatics
inferredcites →https://doi.org/10.1371/journal.pbio.0060135openalex-snapshot
The Evolution of the DLK1-DIO3 Imprinted Domain in Mammals
inferredcites →https://doi.org/10.1371/journal.pgen.0020148openalex-snapshot
The Influence of Recombination on Human Genetic Diversity
inferredcites →https://doi.org/10.1371/journal.pgen.0030074openalex-snapshot
A Method to Address Differential Bias in Genotyping in Large-Scale Association Studies
inferredcites →https://doi.org/10.1371/journal.pone.0004352openalex-snapshot
At Least Ten Genes Define the Imprinted Dlk1-Dio3 Cluster on Mouse Chromosome 12qF1
inferredcites →https://doi.org/10.14670/hh-15.119openalex-snapshot
The role of the epidermal growth factor-like protein dlk in cell differentiation.

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Macrophage Migration Inhibitory Factor Alleviates Irradiation-Induced Injury in BMSCs Via the LncRNA MEG3/NOX4 Axis
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Transient neonatal diabetes mellitus type 1
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Islet Epigenetic Impacts on β‐Cell Identity and Function
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Genetic association analyses of atopic illness and proinflammatory cytokine genes with type 1 diabetes
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MEG3 imprinted gene contribution in tumorigenesis
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Islet Epigenetic Impacts on β‐Cell Identity and Function
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The expression levels of long noncoding RNAs lnc0640 and lnc5150 and its gene single‐nucleotide polymorphisms in rheumatoid arthritis patients
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Downregulation of Long Noncoding RNA Meg3 Affects Insulin Synthesis and Secretion in Mouse Pancreatic Beta Cells
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Melatonin inhibits Müller cell activation and pro‐inflammatory cytokine production via upregulating the MEG3/miR‐204/Sirt1 axis in experimental diabetic retinopathy
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Diabetes and Genetics: A Relationship Between Genetic Risk Alleles, Clinical Phenotypes and Therapeutic Approaches
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Noncoding Gene Families of the Human Genome
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A Role for lncRNAs in Regulating Inflammatory and Autoimmune Responses Underlying Type 1 Diabetes
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Functional Implications of Intergenic GWAS SNPs in Immune-Related LncRNAs
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Environmental Effects on Genomic Imprinting in Development and Disease
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Environmental Effects on Genomic Imprinting in Development and Disease
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Machine Learning Techniques for Identifying Diabetes and Its Complications Based on Long Non-coding RNAs
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Studies on Effect of Leaf Roller (Diaphania pulverulentalis) Infestation on the Mineral Composition of Mulberry (Morus Sp.) Varieties
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Impact of Microbes on Autoimmune Diseases
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Lnc-ing non-coding RNAs with metabolism and diabetes: roles of lncRNAs
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Genetik häufiger chronisch-entzündlicher Hauterkrankungen
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Confirmation of novel type 1 diabetes risk loci in families
inferred← citeshttps://doi.org/10.1007/s00125-013-2972-3openalex-snapshot
DNA methylation in monozygotic quadruplets affected by type 1 diabetes
inferred← citeshttps://doi.org/10.1007/s00125-019-05026-1openalex-snapshot
miR-409-3p is reduced in plasma and islet immune infiltrates of NOD diabetic mice and is differentially expressed in people with type 1 diabetes
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The countdown to type 1 diabetes: when, how and why does the clock start?
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A critical review on therapeutic approaches of CRISPR-Cas9 in diabetes mellitus
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Genetic overlap between type 1 diabetes and other autoimmune diseases
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Conditional meta-analysis stratifying on detailed HLA genotypes identifies a novel type 1 diabetes locus around TCF19 in the MHC
inferred← citeshttps://doi.org/10.1007/s00439-012-1246-3openalex-snapshot
Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women’s Health Initiative SHARe Study
inferred← citeshttps://doi.org/10.1007/s00439-020-02162-2openalex-snapshot
Joint modeling of eQTLs and parent-of-origin effects using an orthogonal framework with RNA-seq data
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Partitioning Phenotypic Variance Due to Parent-of-Origin Effects Using Genomic Relatedness Matrices
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Long Noncoding RNA-Sox2OT Knockdown Alleviates Diabetes Mellitus-Induced Retinal Ganglion Cell (RGC) injury
inferred← citeshttps://doi.org/10.1007/s10735-011-9312-zopenalex-snapshot
Expression of non-coding RNA AB063319 derived from Rian gene during mouse development
inferred← citeshttps://doi.org/10.1007/s11010-020-03810-xopenalex-snapshot
Upregulation of long non-coding RNA MEG3 in type 2 diabetes mellitus complicated with vascular disease: a case–control study
inferred← citeshttps://doi.org/10.1007/s11030-025-11453-7openalex-snapshot
Integrative gene target mapping, RNA sequencing, in silico molecular docking, ADMET profiling and molecular dynamics simulation study of marine derived molecules for type 1 diabetes mellitus
inferred← citeshttps://doi.org/10.1007/s11033-022-08122-5openalex-snapshot
The rs3931283/PVT1 and rs7158663/MEG3 polymorphisms are associated with diabetic kidney disease and markers of renal function in patients with type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.1007/s11892-010-0133-3openalex-snapshot
Novel Gene Associations in Type 1 Diabetes
inferred← citeshttps://doi.org/10.1007/s11892-011-0212-0openalex-snapshot
The Past, Present, and Future of Genetic Associations in Type 1 Diabetes
inferred← citeshttps://doi.org/10.1007/s11892-013-0408-6openalex-snapshot
Candidate Genes Expressed in Human Islets and Their Role in the Pathogenesis of Type 1 Diabetes
inferred← citeshttps://doi.org/10.1007/s11892-015-0655-9openalex-snapshot
Genes Affecting β-Cell Function in Type 1 Diabetes
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Progress in Understanding Type 1 Diabetes Through Its Genetic Overlap with Other Autoimmune Diseases
inferred← citeshttps://doi.org/10.1007/s11892-016-0783-xopenalex-snapshot
Biomarkers of β-Cell Stress and Death in Type 1 Diabetes
inferred← citeshttps://doi.org/10.1007/s11892-018-1085-2openalex-snapshot
The Impact of Pancreatic Beta Cell Heterogeneity on Type 1 Diabetes Pathogenesis
inferred← citeshttps://doi.org/10.1007/s11892-018-1091-4openalex-snapshot
Epigenetics Variation and Pathogenesis in Diabetes
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The Genetic Contribution to Type 1 Diabetes
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The Multiple Autoimmune Syndromes. A Clue for the Autoimmune Tautology
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Molecular Mechanisms in Autoimmune Type 1 Diabetes: a Critical Review
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MEG3: an Oncogenic Long Non-coding RNA in Different Cancers
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The Genome-Wide Association Study—A New Era for Common Polygenic Disorders
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Genetic Epidemiology of Psoriasis
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Environmental Influences on Genomic Imprinting
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RNA-Sequencing Reveals Gene Expression and Pathway Signatures in Umbilical Cord Blood Affected by Birth Delivery Mode
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Epigenomic Factors in Human Obesity
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Genetics of Type 1 Diabetes
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The JAK-STAT signaling pathway in inflammatory and autoimmune diseases: Its potential role as a therapeutic target
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Long non-coding RNA-regulated pathways in pancreatic β cells: Their role in diabetes
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Type I interferons as key players in pancreatic β-cell dysfunction in type 1 diabetes
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Transcriptional and translational regulation of cytokine signaling in inflammatory β-cell dysfunction and apoptosis
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Horse serum reduces expression of membrane-bound and soluble isoforms of the preadipocyte marker Delta-like 1 homolog (Dlk1), but is inefficient for adipogenic differentiation of mouse preadipocytes
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Increased Power for Detection of Parent-of-Origin Effects via the Use of Haplotype Estimation
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The placental imprinted DLK1-DIO3 domain: a new link to prenatal and postnatal growth in humans
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Emerging role of long noncoding RNAs in autoimmune diseases
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Maternally expressed gene 3 in metabolic programming
inferred← citeshttps://doi.org/10.1016/j.bbrc.2016.01.164openalex-snapshot
Long noncoding RNA-MEG3 is involved in diabetes mellitus-related microvascular dysfunction
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Genetic examination of hematological parameters in SARS-CoV-2 infection and COVID-19
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Genomic imprinting: A missing piece of the Multiple Sclerosis puzzle?
inferred← citeshttps://doi.org/10.1016/j.biocel.2018.09.004openalex-snapshot
Inhibition of Lincpint expression affects insulin secretion and apoptosis in mouse pancreatic β cells
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Emerging roles of non-coding RNAs in the pathogenesis of type 1 diabetes mellitus
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The interplay between noncoding RNAs and insulin in diabetes
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WITHDRAWN: Single nucleotide polymorphism, a putative driver for the role of long intergeneric non-coding RNA
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A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure
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Tyrosine kinase 2 – Surveillant of tumours and bona fide oncogene
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Association of 32 type 1 diabetes risk loci in Pakistani patients
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The impact of epigenomics on future drug design and new therapies
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Enteroviruses and Type 1 Diabetes: Candidate Genes Linked With Innate Immune Response
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Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice
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Functional diversity of long non-coding RNAs in immune regulation
inferred← citeshttps://doi.org/10.1016/j.gene.2022.146676openalex-snapshot
Male-specific coordinated changes in expression of miRNA genes, but not other genes within the DLK1-DIO3 locus in multiple sclerosis
inferred← citeshttps://doi.org/10.1016/j.genrep.2021.101286openalex-snapshot
Association between MEG3 polymorphisms (rs941576 and rs7158663) and risk of acute ischemic stroke in Egyptian patients
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The stage- and subgroup-specific impact of non-HLA polymorphisms on preclinical type 1 diabetes progression
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Etiology of Type 1 Diabetes
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Genomic imprinting in psoriasis and atopic dermatitis: A review
inferred← citeshttps://doi.org/10.1016/j.jshs.2025.101091openalex-snapshot
Exercise training-induced extracellular miR-136-3p modulates glucose uptake and myogenesis through targeting of NRDC in human skeletal muscle
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The role of imprinted genes in humans
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Genetics of diabetes – Are we missing the genes or the disease?
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Untangling the genetics of beta cell dysfunction and death in type 1 diabetes
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Biological functions and affected signaling pathways by Long Non-Coding RNAs in the immune system
inferred← citeshttps://doi.org/10.1016/j.omtn.2024.102252openalex-snapshot
Lowering an ER stress-regulated long noncoding RNA protects mice from diabetes and isolated pancreatic islets from cell death
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Genetic predisposition to autoimmunity – What have we learned?
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The pancreatic β cell and type 1 diabetes: innocent bystander or active participant?
inferred← citeshttps://doi.org/10.1016/j.tig.2017.01.010openalex-snapshot
Genomics of Islet (Dys)function and Type 2 Diabetes
inferred← citeshttps://doi.org/10.1016/j.tvjl.2011.06.023openalex-snapshot
Expanded dog leukocyte antigen (DLA) single nucleotide polymorphism (SNP) genotyping reveals spurious class II associations
inferred← citeshttps://doi.org/10.1016/j.xcrm.2024.101591openalex-snapshot
A set of circulating microRNAs belonging to the 14q32 chromosome locus identifies two subgroups of individuals with recent-onset type 1 diabetes
inferred← citeshttps://doi.org/10.1016/j.xhgg.2021.100039openalex-snapshot
Genome-wide survey of parent-of-origin-specific associations across clinical traits derived from electronic health records
inferred← citeshttps://doi.org/10.1016/s2213-8587(23)00190-0openalex-snapshot
Maternal type 1 diabetes and relative protection against offspring transmission
inferred← citeshttps://doi.org/10.1017/s0016672320000026openalex-snapshot
A robust test for X-chromosome genetic association accounting for X-chromosome inactivation and imprinting
inferred← citeshttps://doi.org/10.1038/cti.2017.51openalex-snapshot
Type 1 diabetes genome‐wide association studies: not to be lost in translation
inferred← citeshttps://doi.org/10.1038/gene.2013.32openalex-snapshot
Genetic control of murine invariant natural killer T cells maps to multiple type 1 diabetes regions
inferred← citeshttps://doi.org/10.1038/jhg.2015.113openalex-snapshot
Kagami–Ogata syndrome: a clinically recognizable upd(14)pat and related disorder affecting the chromosome 14q32.2 imprinted region
inferred← citeshttps://doi.org/10.1038/jhg.2016.70openalex-snapshot
Long noncoding RNA variations in cardiometabolic diseases
inferred← citeshttps://doi.org/10.1038/jid.2011.395openalex-snapshot
Psoriasis and Other Complex Trait Dermatoses: From Loci to Functional Pathways
inferred← citeshttps://doi.org/10.1038/mp.2014.21openalex-snapshot
Astrocytic abnormalities and global DNA methylation patterns in depression and suicide
inferred← citeshttps://doi.org/10.1038/ncomms12631openalex-snapshot
Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice
inferred← citeshttps://doi.org/10.1038/ncomms13490openalex-snapshot
Epigenetic and genetic components of height regulation
inferred← citeshttps://doi.org/10.1038/ng.2395openalex-snapshot
Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis
inferred← citeshttps://doi.org/10.1038/ng.2578openalex-snapshot
Seven new loci associated with age-related macular degeneration
inferred← citeshttps://doi.org/10.1038/ng.3247openalex-snapshot
Large-scale whole-genome sequencing of the Icelandic population
inferred← citeshttps://doi.org/10.1038/ng.694openalex-snapshot
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
inferred← citeshttps://doi.org/10.1038/nm.3385openalex-snapshot
Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c
inferred← citeshttps://doi.org/10.1038/nrendo.2014.229openalex-snapshot
Long non-coding RNAs as regulators of the endocrine system
inferred← citeshttps://doi.org/10.1038/nrendo.2016.30openalex-snapshot
Viral infections in type 1 diabetes mellitus — why the β cells?
inferred← citeshttps://doi.org/10.1038/nrg2809openalex-snapshot
Missing heritability and strategies for finding the underlying causes of complex disease
inferred← citeshttps://doi.org/10.1038/nrg3032openalex-snapshot
Genomic imprinting: the emergence of an epigenetic paradigm
inferred← citeshttps://doi.org/10.1038/nrg3543openalex-snapshot
Genomic imprinting and parent-of-origin effects on complex traits
inferred← citeshttps://doi.org/10.1038/nrrheum.2017.162openalex-snapshot
The role of long non-coding RNAs in rheumatic diseases
inferred← citeshttps://doi.org/10.1038/s41418-026-01669-xopenalex-snapshot
Differential immune- and apoptosis-related gene signatures in pancreatic alpha and beta cells contribute to their fate in type 1 diabetes
inferred← citeshttps://doi.org/10.1038/s41419-019-1399-2openalex-snapshot
Long non-coding RNA Irm enhances myogenic differentiation by interacting with MEF2D
inferred← citeshttps://doi.org/10.1038/s41586-019-1457-zopenalex-snapshot
Exome sequencing of Finnish isolates enhances rare-variant association power
inferred← citeshttps://doi.org/10.1038/s41588-018-0216-7openalex-snapshot
Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes
inferred← citeshttps://doi.org/10.1038/s41598-018-35252-3openalex-snapshot
DLK proteins modulate NOTCH signaling to influence a brown or white 3T3-L1 adipocyte fate
inferred← citeshttps://doi.org/10.1038/s41598-019-40501-0openalex-snapshot
RNA-seq of Isolated Chromaffin Cells Highlights the Role of Sex-Linked and Imprinted Genes in Adrenal Medulla Development
inferred← citeshttps://doi.org/10.1038/s41598-020-60758-0openalex-snapshot
Longitudinal DNA methylation differences precede type 1 diabetes
inferred← citeshttps://doi.org/10.1038/s41598-020-68212-xopenalex-snapshot
Genomic imprinting analyses identify maternal effects as a cause of phenotypic variability in type 1 diabetes and rheumatoid arthritis
inferred← citeshttps://doi.org/10.1038/s41598-024-60265-6openalex-snapshot
Association of lncRNA MEG3 rs941576 polymorphism, expression profile, and its related targets with the risk of obesity-related colorectal cancer: potential clinical insights
inferred← citeshttps://doi.org/10.1042/bse0480187openalex-snapshot
Genomic imprinting and human disease
inferred← citeshttps://doi.org/10.1042/bsr20171157openalex-snapshot
Roles of miRNAs and long noncoding RNAs in the progression of diabetic retinopathy
inferred← citeshttps://doi.org/10.1042/bsr20202160openalex-snapshot
Epigenetic modification and therapeutic targets of diabetes mellitus
inferred← citeshttps://doi.org/10.1080/08830185.2019.1648454openalex-snapshot
Emerging roles of noncoding RNAs in T cell differentiation and functions in autoimmune diseases
inferred← citeshttps://doi.org/10.1080/13813455.2020.1784951openalex-snapshot
RETRACTED ARTICLE: Long non-coding RNA MEG3 and its genetic variant rs941576 are associated with rheumatoid arthritis pathogenesis in Egyptian patients
inferred← citeshttps://doi.org/10.1080/13813455.2021.2023580openalex-snapshot
Long non-coding RNAs as emerging regulators of miRNAs and epigenetics in diabetes-related chronic kidney disease
inferred← citeshttps://doi.org/10.1080/15476286.2016.1172756openalex-snapshot
Long non-coding RNA: Functional agent for disease traits
inferred← citeshttps://doi.org/10.1080/15592294.2019.1640547openalex-snapshot
Epigenome-wide association study of DNA methylation and microRNA expression highlights novel pathways for human complex traits
inferred← citeshttps://doi.org/10.1080/15592294.2022.2111755openalex-snapshot
Placental DNA methylation in pregnancies complicated by maternal diabetes and/or obesity: State of the art and research gaps
inferred← citeshttps://doi.org/10.1080/21691401.2020.1725535openalex-snapshot
Protocatechuic aldehyde mitigates hydrogen peroxide-triggered PC12 cell damage by down-regulating MEG3
inferred← citeshttps://doi.org/10.1080/26895293.2023.2220537openalex-snapshot
Analysis of lncRNA and mRNA expression profiles in diabetic peripheral neuropathy based on weighted gene co-expression network analysis
inferred← citeshttps://doi.org/10.1089/ars.2017.7315openalex-snapshot
Long Noncoding RNAs in Diabetes and Diabetic Complications
inferred← citeshttps://doi.org/10.1089/gtmb.2017.0009openalex-snapshot
Association Analysis of Single Nucleotide Polymorphisms in C1QTNF6 , RAC2 , and an Intergenic Region at 14q32.2 with Graves' Disease in Chinese Han Population
inferred← citeshttps://doi.org/10.1089/gtmb.2017.0059openalex-snapshot
GLIS3 and TYK2 Single Nucleotide Polymorphisms Are Not Associated with Dermatomyositis/Polymyositis in Chinese Han Population
inferred← citeshttps://doi.org/10.1093/bfgp/elq026openalex-snapshot
The epigenomic interface between genome and environment in common complex diseases
inferred← citeshttps://doi.org/10.1093/bib/bbu017openalex-snapshot
Review of statistical methodologies for the detection of parent-of-origin effects in family trio genome-wide association data with binary disease traits
inferred← citeshttps://doi.org/10.1093/bib/bbw060openalex-snapshot
Long non-coding RNAs and complex diseases: from experimental results to computational models
inferred← citeshttps://doi.org/10.1093/brain/awr010openalex-snapshot
Tyrosine kinase 2 variant influences T lymphocyte polarization and multiple sclerosis susceptibility
inferred← citeshttps://doi.org/10.1093/hmg/ddq332openalex-snapshot
Ancestral paternal genotype controls body weight and food intake for multiple generations
inferred← citeshttps://doi.org/10.1093/hmg/dds098openalex-snapshot
Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes
inferred← citeshttps://doi.org/10.1093/hmg/dds225openalex-snapshot
Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB–FKBPL–NOTCH4 region of chromosome 6p21.3
inferred← citeshttps://doi.org/10.1093/humupd/dmz025openalex-snapshot
In-utero stress and mode of conception: impact on regulation of imprinted genes, fetal development and future health
inferred← citeshttps://doi.org/10.1093/molehr/gaq028openalex-snapshot
Extending the maternal-zygotic effect with genomic imprinting
inferred← citeshttps://doi.org/10.1093/nar/gkq912openalex-snapshot
T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research
inferred← citeshttps://doi.org/10.1096/fj.15-273649openalex-snapshot
Multiple microRNAs within the 14q32 cluster target the mRNAs of major type 1 diabetes autoantigens IA‐2, IA‐2β, and GAD65
inferred← citeshttps://doi.org/10.1097/aci.0b013e32833dc75eopenalex-snapshot
Genome-wide approaches to the etiology of eczema
inferred← citeshttps://doi.org/10.1097/fpc.0000000000000534openalex-snapshot
MEG3 in hematologic malignancies: from the role of disease biomarker to therapeutic target
inferred← citeshttps://doi.org/10.1097/med.0000000000000141openalex-snapshot
Noncoding RNAs in β cell biology
inferred← citeshttps://doi.org/10.1097/med.0000000000000399openalex-snapshot
Potential role of type I interferon in the pathogenic process leading to type 1 diabetes
inferred← citeshttps://doi.org/10.1097/tp.0000000000001463openalex-snapshot
Differential Expression of Long Noncoding RNAs During Cardiac Allograft Rejection
inferred← citeshttps://doi.org/10.1097/ypg.0000000000000297openalex-snapshot
Epigenetic marks in suicide: a review
inferred← citeshttps://doi.org/10.1098/rstb.2014.0074openalex-snapshot
The role and interaction of imprinted genes in human fetal growth
inferred← citeshttps://doi.org/10.1101/120022openalex-snapshot
Type 1 diabetes genome-wide association analysis with imputation identifies five new risk regions
inferred← citeshttps://doi.org/10.1101/2022.11.21.517323openalex-snapshot
Identification of Key Genes and Underlying Mechanisms in Cystic Fibrosis and its Associated Complications Based on Bioinformatics Analysis of Next Generation Sequencing Data Analysis
inferred← citeshttps://doi.org/10.1101/2022.12.27.522037openalex-snapshot
Deucravacitinib, a tyrosine kinase 2 pseudokinase inhibitor, protects human beta cells against proinflammatory insults
inferred← citeshttps://doi.org/10.1101/2023.09.29.560131openalex-snapshot
Effects of Developmental Lead and Phthalate Exposures on DNA Methylation in Adult Mouse Blood, Brain, and Liver Identifies Tissue- and Sex-Specific Changes with Implications for Genomic Imprinting
inferred← citeshttps://doi.org/10.1101/2023.10.08.23296650openalex-snapshot
A set of circulating microRNAs belonging to the 14q32 chromosomic locus identifies two clinically and phenotypically different subgroups of individuals with recent onset Stage 3 type 1 diabetes
inferred← citeshttps://doi.org/10.1101/464255openalex-snapshot
Exome sequencing identifies high-impact trait-associated alleles enriched in Finns
inferred← citeshttps://doi.org/10.1101/579748openalex-snapshot
Epistatic Networks Associated with Parent-of-Origin Effects on Metabolic Traits
inferred← citeshttps://doi.org/10.1101/732792openalex-snapshot
A statistical method for joint estimation of cis -eQTLs and parent-of-orign effects using an orthogonal framework with RNA-seq data
inferred← citeshttps://doi.org/10.1101/gr.212720.116openalex-snapshot
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type–specific expression changes in type 2 diabetes
inferred← citeshttps://doi.org/10.1111/1753-0407.12363openalex-snapshot
Characteristics of youth with type 1 diabetes (T1D) with and without a parent with T1D in the T1D exchange clinic registry
inferred← citeshttps://doi.org/10.1111/1753-0407.70280openalex-snapshot
Human β‐Cell Dedifferentiation and Diabetes
inferred← citeshttps://doi.org/10.1111/age.12712openalex-snapshot
Long non‐coding MEG 3 is a marker for skeletal muscle development and meat production traits in pigs
inferred← citeshttps://doi.org/10.1111/cei.12362openalex-snapshot
Multi-parametric flow cytometric and genetic investigation of the peripheral B cell compartment in human type 1 diabetes
inferred← citeshttps://doi.org/10.1111/dom.12162openalex-snapshot
Candidate genes for type 1 diabetes modulate pancreatic islet inflammation and β ‐cell apoptosis
inferred← citeshttps://doi.org/10.1111/dom.12714openalex-snapshot
Role of long non‐coding RNAs in the determination of β‐cell identity
inferred← citeshttps://doi.org/10.1111/dom.14777openalex-snapshot
The missing heritability in type 1 diabetes
inferred← citeshttps://doi.org/10.1111/j.1399-0004.2011.01790.xopenalex-snapshot
Parent of origin effects
inferred← citeshttps://doi.org/10.1111/jcmm.15759openalex-snapshot
Long non‐coding RNA MEG3 promotes autophagy and apoptosis of nasopharyngeal carcinoma cells via PTEN up‐regulation by binding to microRNA‐21
inferred← citeshttps://doi.org/10.1111/jdi.13432openalex-snapshot
Placental maternally expressed gene 3 differentially methylated region methylation profile is associated with maternal glucose concentration and newborn birthweight
inferred← citeshttps://doi.org/10.1111/pedi.12387openalex-snapshot
Role of DNA methylation at the placentalRTL1gene locus in type 1 diabetes
inferred← citeshttps://doi.org/10.1111/tan.12143openalex-snapshot
Transmission disequilibrium analysis of 31 type 1 diabetes susceptibility loci in Finnish families
inferred← citeshttps://doi.org/10.1126/sciadv.adw8946openalex-snapshot
Longitudinal monitoring of type 1 diabetes progression to disease onset
inferred← citeshttps://doi.org/10.1126/scitranslmed.aad9943openalex-snapshot
Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression
inferred← citeshttps://doi.org/10.1128/iai.00558-21openalex-snapshot
Borrelia burgdorferi Is a Poor Inducer of Gamma Interferon: Amplification Induced by Interleukin-12
inferred← citeshttps://doi.org/10.1136/annrheumdis-2014-205440openalex-snapshot
Genotyping of immune-related genetic variants identifies TYK2 as a novel associated locus for idiopathic inflammatory myopathies
inferred← citeshttps://doi.org/10.1136/ard.2010.133660openalex-snapshot
Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility
inferred← citeshttps://doi.org/10.1136/gut.2009.199679openalex-snapshot
New IBD genetics: common pathways with other diseases
inferred← citeshttps://doi.org/10.1136/jmedgenet-2011-100242openalex-snapshot
Studying the epigenome using next generation sequencing
inferred← citeshttps://doi.org/10.1146/annurev-genom-091212-153450openalex-snapshot
Mapping of Immune-Mediated Disease Genes
inferred← citeshttps://doi.org/10.1152/physiolgenomics.00253.2010openalex-snapshot
Multisite haplotype on cattle chromosome 3 is associated with quantitative trait locus effects on lactation traits
inferred← citeshttps://doi.org/10.1152/physrev.00003.2010openalex-snapshot
Type 1 Diabetes: Etiology, Immunology, and Therapeutic Strategies
inferred← citeshttps://doi.org/10.1155/2013/254874openalex-snapshot
Altered Immune Regulation in Type 1 Diabetes
inferred← citeshttps://doi.org/10.1155/2014/738512openalex-snapshot
Type I Diabetes Mellitus: Genetic Factors and Presumptive Enteroviral Etiology or Protection
inferred← citeshttps://doi.org/10.1155/2023/5367637openalex-snapshot
DNA Methylation Near DLGAP2 May Mediate the Relationship between Family History of Type 1 Diabetes and Type 1 Diabetes Risk
inferred← citeshttps://doi.org/10.1159/000487983openalex-snapshot
Long Noncoding RNA Meg3 Regulates Mafa Expression in Mouse Beta Cells by Inactivating Rad21, Smc3 or Sin3α
inferred← citeshttps://doi.org/10.1161/circgenetics.114.000496openalex-snapshot
Serum Lipid Levels, Body Mass Index, and Their Role in Coronary Artery Calcification
inferred← citeshttps://doi.org/10.1167/iovs.18-24082openalex-snapshot
Genome-Wide Association Study Identifies a Susceptibility Locus for Comitant Esotropia and Suggests a Parent-of-Origin Effect
inferred← citeshttps://doi.org/10.1177/0961203313492870openalex-snapshot
The development of genome-wide association studies and their application to complex diseases, including lupus
inferred← citeshttps://doi.org/10.1177/0962280216680243openalex-snapshot
Detection of imprinting effects for qualitative traits on X chromosome based on nuclear families
inferred← citeshttps://doi.org/10.1177/1120672120970401openalex-snapshot
Research progress of lncRNAs in diabetic retinopathy
inferred← citeshttps://doi.org/10.1186/1753-6561-5-s3-s2openalex-snapshot
Comparison of analyses of the QTLMAS XIV common dataset. II: QTL analysis
inferred← citeshttps://doi.org/10.1186/gm176openalex-snapshot
Genomic imprinting in diabetes
inferred← citeshttps://doi.org/10.1186/s12859-021-04207-3openalex-snapshot
Lantern: an integrative repository of functional annotations for lncRNAs in the human genome
inferred← citeshttps://doi.org/10.1186/s12864-015-1233-xopenalex-snapshot
Sequence and analysis of a whole genome from Kuwaiti population subgroup of Persian ancestry
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