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Cell cycle, CDKs and cancer: a changing paradigm
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1 of the 177 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-28): 10.1016/j.stem.2007.04.001 (notice 2023-06-01).
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1007/bf01497322openalex-snapshot
Zur Frage der Entstehung maligner Tumoren
inferredcites →https://doi.org/10.1016/0092-8674(83)90420-8openalex-snapshot
Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division
inferredcites →https://doi.org/10.1016/0092-8674(89)90507-2openalex-snapshot
The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element
inferredcites →https://doi.org/10.1016/0092-8674(89)90508-4openalex-snapshot
The retinoblastoma protein is phosphorylated during specific phases of the cell cycle
inferredcites →https://doi.org/10.1016/0092-8674(89)90517-5openalex-snapshot
Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation
inferredcites →https://doi.org/10.1016/0092-8674(91)90042-wopenalex-snapshot
Isolation of three novel human cyclins by rescue of G1 cyclin (cln) function in yeast
inferredcites →https://doi.org/10.1016/0092-8674(91)90101-4openalex-snapshot
Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle
inferredcites →https://doi.org/10.1016/0092-8674(92)90360-oopenalex-snapshot
Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins
inferredcites →https://doi.org/10.1016/0092-8674(92)90541-jopenalex-snapshot
ras-Induced hyperplasia occurs with mutation of p53, but activated ras and myc together can induce carcinoma without p53 mutation
inferredcites →https://doi.org/10.1016/0092-8674(92)90562-qopenalex-snapshot
Regulation of the specific DNA binding function of p53
inferredcites →https://doi.org/10.1016/0092-8674(92)90593-2openalex-snapshot
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
inferredcites →https://doi.org/10.1016/0092-8674(94)90257-7openalex-snapshot
Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation
inferredcites →https://doi.org/10.1016/0092-8674(94)90572-xopenalex-snapshot
Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
inferredcites →https://doi.org/10.1016/0092-8674(94)90573-8openalex-snapshot
p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21
inferredcites →https://doi.org/10.1016/j.bbrc.2007.01.049openalex-snapshot
CDK13/CDC2L5 interacts with L-type cyclins and regulates alternative splicing
inferredcites →https://doi.org/10.1016/j.ccr.2005.05.006openalex-snapshot
Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27Kip1 and p21Cip1
inferredcites →https://doi.org/10.1016/j.ccr.2005.12.012openalex-snapshot
Requirement for CDK4 kinase function in breast cancer
inferredcites →https://doi.org/10.1016/j.ccr.2005.12.019openalex-snapshot
Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis
inferredcites →https://doi.org/10.1016/j.ccr.2005.12.026openalex-snapshot
Is Cyclin D1-CDK4 kinase a bona fide cancer target?
inferredcites →https://doi.org/10.1016/j.ccr.2006.10.019openalex-snapshot
Mad2 Overexpression Promotes Aneuploidy and Tumorigenesis in Mice
inferredcites →https://doi.org/10.1016/j.ccr.2006.12.003openalex-snapshot
Aneuploidy Acts Both Oncogenically and as a Tumor Suppressor
inferredcites →https://doi.org/10.1016/j.ccr.2008.01.001openalex-snapshot
Identification of CDK10 as an Important Determinant of Resistance to Endocrine Therapy for Breast Cancer
inferredcites →https://doi.org/10.1016/j.ceb.2006.01.001openalex-snapshot
CDK activation by non-cyclin proteins
inferredcites →https://doi.org/10.1016/j.ceb.2007.11.008openalex-snapshot
Polo and Aurora kinases — lessons derived from chemical biology
inferredcites →https://doi.org/10.1016/j.ceb.2008.09.003openalex-snapshot
Cdk-counteracting phosphatases unlock mitotic exit
inferredcites →https://doi.org/10.1016/j.cell.2004.07.025openalex-snapshot
Mouse Development and Cell Proliferation in the Absence of D-Cyclins
inferredcites →https://doi.org/10.1016/j.cell.2004.08.002openalex-snapshot
Mammalian Cells Cycle without the D-Type Cyclin-Dependent Kinases Cdk4 and Cdk6
inferredcites →https://doi.org/10.1016/j.cell.2007.11.047openalex-snapshot
NFATc1 Balances Quiescence and Proliferation of Skin Stem Cells
inferredcites →https://doi.org/10.1016/j.cellsig.2005.02.005openalex-snapshot
Role of CDK/cyclin complexes in transcription and RNA splicing
inferredcites →https://doi.org/10.1016/j.coph.2008.06.013openalex-snapshot
Emerging cancer therapeutic opportunities by inhibiting mitotic kinases
inferredcites →https://doi.org/10.1016/j.cub.2003.09.024openalex-snapshot
Cdk2 Knockout Mice Are Viable
inferredcites →https://doi.org/10.1016/j.devcel.2006.03.004openalex-snapshot
Combined Loss of Cdk2 and Cdk4 Results in Embryonic Lethality and Rb Hypophosphorylation
inferredcites →https://doi.org/10.1016/j.devcel.2007.08.008openalex-snapshot
Bub1 Maintains Centromeric Cohesion by Activation of the Spindle Checkpoint
inferredcites →https://doi.org/10.1016/j.devcel.2008.04.014openalex-snapshot
Polo on the Rise—from Mitotic Entry to Cytokinesis with Plk1
inferredcites →https://doi.org/10.1016/j.dnarep.2008.09.002openalex-snapshot
Dual role of CDKs in DNA repair: To be, or not to be
inferredcites →https://doi.org/10.1016/j.exphem.2006.11.005openalex-snapshot
Loss of the tumor suppressor p15Ink4b enhances myeloid progenitor formation from common myeloid progenitors
inferredcites →https://doi.org/10.1016/j.gde.2006.12.008openalex-snapshot
Cell cycle kinases in cancer
inferredcites →https://doi.org/10.1016/j.molcel.2006.11.029openalex-snapshot
Kinase-Independent Function of Cyclin E
inferredcites →https://doi.org/10.1016/j.molcel.2007.02.003openalex-snapshot
Requirements for Cdk7 in the Assembly of Cdk1/Cyclin B and Activation of Cdk2 Revealed by Chemical Genetics in Human Cells
inferredcites →https://doi.org/10.1016/j.molcel.2008.02.027openalex-snapshot
Cdc20 and Cks Direct the Spindle Checkpoint-Independent Destruction of Cyclin A
inferredcites →https://doi.org/10.1016/j.molonc.2007.03.001openalex-snapshot
Mice thrive without Cdk4 and Cdk2
inferredcites →https://doi.org/10.1016/j.stem.2007.04.001openalex-snapshot
RETRACTED: shRNA Knockdown of Bmi-1 Reveals a Critical Role for p21-Rb Pathway in NSC Self-Renewal during Development
inferredcites →https://doi.org/10.1016/j.tibs.2005.09.005openalex-snapshot
Mammalian cyclin-dependent kinases
inferredcites →https://doi.org/10.1016/j.tips.2007.10.012openalex-snapshot
CDK inhibitors in cancer therapy: what is next?
inferredcites →https://doi.org/10.1016/s0092-8674(00)80788-6openalex-snapshot
Rescue of Cyclin D1 Deficiency by Knockin Cyclin E
inferredcites →https://doi.org/10.1016/s0092-8674(00)81519-6openalex-snapshot
Cdk Phosphorylation Triggers Sequential Intramolecular Interactions that Progressively Block Rb Functions as Cells Move through G1
inferredcites →https://doi.org/10.1016/s0092-8674(00)81902-9openalex-snapshot
Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a
inferredcites →https://doi.org/10.1016/s0092-8674(03)00645-7openalex-snapshot
Cyclin E Ablation in the Mouse
inferredcites →https://doi.org/10.1016/s0092-8674(04)00300-9openalex-snapshot
Cyclin C/Cdk3 Promotes Rb-Dependent G0 Exit
inferredcites →https://doi.org/10.1016/s0304-419x(02)00037-9openalex-snapshot
Cyclin D-dependent kinases, INK4 inhibitors and cancer
inferredcites →https://doi.org/10.1016/s1535-6108(03)00053-9openalex-snapshot
Proliferation of cancer cells despite CDK2 inhibition
inferredcites →https://doi.org/10.1038/256547a0openalex-snapshot
Genetic control of cell size at cell division in yeast
inferredcites →https://doi.org/10.1038/32688openalex-snapshot
Mutations of mitotic checkpoint genes in human cancers
inferredcites →https://doi.org/10.1038/327031a0openalex-snapshot
Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2
inferredcites →https://doi.org/10.1038/35053094openalex-snapshot
MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells
inferredcites →https://doi.org/10.1038/35082500openalex-snapshot
Specific protection against breast cancers by cyclin D1 ablation
inferredcites →https://doi.org/10.1038/35106065openalex-snapshot
To cycle or not to cycle: a critical decision in cancer
inferredcites →https://doi.org/10.1038/356215a0openalex-snapshot
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
inferredcites →https://doi.org/10.1038/358083a0openalex-snapshot
Wild-type p53 activates transcription in vitro
inferredcites →https://doi.org/10.1038/366701a0openalex-snapshot
p21 is a universal inhibitor of cyclin kinases
inferredcites →https://doi.org/10.1038/366704a0openalex-snapshot
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
inferredcites →https://doi.org/10.1038/8751openalex-snapshot
Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in β-islet cell hyperplasia
inferredcites →https://doi.org/10.1038/emboj.2008.195openalex-snapshot
Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicity
inferredcites →https://doi.org/10.1038/nature03097openalex-snapshot
Cell-cycle checkpoints and cancer
inferredcites →https://doi.org/10.1038/nature03404openalex-snapshot
CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair
inferredcites →https://doi.org/10.1038/nature03445openalex-snapshot
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
inferredcites →https://doi.org/10.1038/nature03482openalex-snapshot
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
inferredcites →https://doi.org/10.1038/nature03485openalex-snapshot
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
inferredcites →https://doi.org/10.1038/nature03841openalex-snapshot
Oncogene-induced senescence as an initial barrier in lymphoma development
inferredcites →https://doi.org/10.1038/nature03890openalex-snapshot
BRAFE600-associated senescence-like cell cycle arrest of human naevi
inferredcites →https://doi.org/10.1038/nature03918openalex-snapshot
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
inferredcites →https://doi.org/10.1038/nature04652openalex-snapshot
The reversibility of mitotic exit in vertebrate cells
inferredcites →https://doi.org/10.1038/nature05091openalex-snapshot
Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing
inferredcites →https://doi.org/10.1038/nature05092openalex-snapshot
p16INK4a induces an age-dependent decline in islet regenerative potential
inferredcites →https://doi.org/10.1038/nature05159openalex-snapshot
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a
inferredcites →https://doi.org/10.1038/nature05268openalex-snapshot
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
inferredcites →https://doi.org/10.1038/nature05327openalex-snapshot
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
inferredcites →https://doi.org/10.1038/nature05584openalex-snapshot
14-3-3σ controls mitotic translation to facilitate cytokinesis
inferredcites →https://doi.org/10.1038/nature05610openalex-snapshot
Patterns of somatic mutation in human cancer genomes
inferredcites →https://doi.org/10.1038/nature06046openalex-snapshot
Cdk1 is sufficient to drive the mammalian cell cycle
inferredcites →https://doi.org/10.1038/nature07034openalex-snapshot
Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells
inferredcites →https://doi.org/10.1038/nature07179openalex-snapshot
CDK8 is a colorectal cancer oncogene that regulates β-catenin activity
inferredcites →https://doi.org/10.1038/nature07215openalex-snapshot
CDK targets Sae2 to control DNA-end resection and homologous recombination
inferredcites →https://doi.org/10.1038/nature07310openalex-snapshot
E2F1 represses β-catenin transcription and is antagonized by both pRB and CDK8
inferredcites →https://doi.org/10.1038/ncb1126openalex-snapshot
In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C
inferredcites →https://doi.org/10.1038/ncb1214openalex-snapshot
Negative cell-cycle regulators cooperatively control self-renewal and differentiation of haematopoietic stem cells
inferredcites →https://doi.org/10.1038/ncb1284openalex-snapshot
Cdc2–cyclin E complexes regulate the G1/S phase transition
inferredcites →https://doi.org/10.1038/ncb1410openalex-snapshot
Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C
inferredcites →https://doi.org/10.1038/ncb1742openalex-snapshot
Genomic stability and tumour suppression by the APC/C cofactor Cdh1
inferredcites →https://doi.org/10.1038/ncb1768openalex-snapshot
The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory
inferredcites →https://doi.org/10.1038/ng0197-83openalex-snapshot
Delayed early embryonic lethality following disruption of the murine cyclin A2 gene
inferredcites →https://doi.org/10.1038/ng1232openalex-snapshot
Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice
inferredcites →https://doi.org/10.1038/ng1382openalex-snapshot
BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice
inferredcites →https://doi.org/10.1038/ng1449openalex-snapshot
Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B
inferredcites →https://doi.org/10.1038/ng1861openalex-snapshot
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
inferredcites →https://doi.org/10.1038/ng1937openalex-snapshot
Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation
inferredcites →https://doi.org/10.1038/nm0297-227openalex-snapshot
Decreased levels of the cell-cycle inhibitor p27Kip1 protein: Prognostic implications in primary breast cancer
inferredcites →https://doi.org/10.1038/nm0297-231openalex-snapshot
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
inferredcites →https://doi.org/10.1038/nrc1502openalex-snapshot
Aurora-kinase inhibitors as anticancer agents
inferredcites →https://doi.org/10.1038/nrc1714openalex-snapshot
On the road to cancer: aneuploidy and the mitotic checkpoint
inferredcites →https://doi.org/10.1038/nrc1841openalex-snapshot
Targeting polo-like kinase 1 for cancer therapy
inferredcites →https://doi.org/10.1038/nrc1881openalex-snapshot
Ubiquitin ligases: cell-cycle control and cancer
inferredcites →https://doi.org/10.1038/nrc2249openalex-snapshot
Oncogenes and tumour suppressors take on centrosomes
inferredcites →https://doi.org/10.1038/nrc2251openalex-snapshot
CHK2 kinase: cancer susceptibility and cancer therapy – two sides of the same coin?
inferredcites →https://doi.org/10.1038/nrg2268openalex-snapshot
Genome instability: a mechanistic view of its causes and consequences
inferredcites →https://doi.org/10.1038/nrg2380openalex-snapshot
Single-strand break repair and genetic disease
inferredcites →https://doi.org/10.1038/nrm1988openalex-snapshot
The anaphase promoting complex/cyclosome: a machine designed to destroy
inferredcites →https://doi.org/10.1038/nrm2105openalex-snapshot
Multiple levels of cyclin specificity in cell-cycle control
inferredcites →https://doi.org/10.1038/nrm2163openalex-snapshot
The spindle-assembly checkpoint in space and time
inferredcites →https://doi.org/10.1038/nrm2276openalex-snapshot
Finishing mitosis, one step at a time
inferredcites →https://doi.org/10.1038/nrm2450openalex-snapshot
ATR: an essential regulator of genome integrity
inferredcites →https://doi.org/10.1038/nrm2510openalex-snapshot
Cyclin-dependent kinases and cell-cycle transitions: does one fit all?
inferredcites →https://doi.org/10.1038/nrm2514openalex-snapshot
Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer
inferredcites →https://doi.org/10.1038/onc.2008.161openalex-snapshot
Roles of cyclins A and E in induction of centrosome amplification in p53-compromised cells
inferredcites →https://doi.org/10.1038/sj.embor.7400639openalex-snapshot
The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation
inferredcites →https://doi.org/10.1038/sj.onc.1206506openalex-snapshot
Genetic rescue of Cdk4 null mice restores pancreatic β-cell proliferation but not homeostatic cell number
inferredcites →https://doi.org/10.1038/sj.onc.1206888openalex-snapshot
Characterization of the abnormal pancreatic development, reduced growth and infertility in Cdk4 mutant mice
inferredcites →https://doi.org/10.1038/sj.onc.1208608openalex-snapshot
Cell cycle in mouse development
inferredcites →https://doi.org/10.1038/sj.onc.1209310openalex-snapshot
Cyclin-dependent kinase 2 is dispensable for normal centrosome duplication but required for oncogene-induced centrosome overduplication
inferredcites →https://doi.org/10.1038/sj.onc.1210703openalex-snapshot
The ubiquitin ligase APCCdh1 is required to maintain genome integrity in primary human cells
inferredcites →https://doi.org/10.1073/pnas.041596198openalex-snapshot
A premature-termination mutation in the Mus musculus cyclin-dependent kinase 3 gene
inferredcites →https://doi.org/10.1073/pnas.0711030105openalex-snapshot
p21 Cip1 restricts neuronal proliferation in the subgranular zone of the dentate gyrus of the hippocampus
inferredcites →https://doi.org/10.1073/pnas.0711355105openalex-snapshot
Nuclear localization of Cdk5 is a key determinant in the postmitotic state of neurons
inferredcites →https://doi.org/10.1073/pnas.241338598openalex-snapshot
Invasive melanoma in Cdk4-targeted mice
inferredcites →https://doi.org/10.1073/pnas.66.2.352openalex-snapshot
Genetic Control of the Cell-Division Cycle in Yeast, I. Detection of Mutants
inferredcites →https://doi.org/10.1073/pnas.89.16.7491openalex-snapshot
Wild-type p53 is a cell cycle checkpoint determinant following irradiation.
inferredcites →https://doi.org/10.1073/pnas.95.8.4344openalex-snapshot
Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero
inferredcites →https://doi.org/10.1074/jbc.m409080200openalex-snapshot
Cdk4 Is Indispensable for Postnatal Proliferation of the Anterior Pituitary
inferredcites →https://doi.org/10.1083/jcb.121.1.101openalex-snapshot
Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts.
inferredcites →https://doi.org/10.1083/jcb.200702031openalex-snapshot
Cdk2 is critical for proliferation and self-renewal of neural progenitor cells in the adult subventricular zone
inferredcites →https://doi.org/10.1083/jcb.200702034openalex-snapshot
An essential role for Cdk1 in S phase control is revealed via chemical genetics in vertebrate cells
inferredcites →https://doi.org/10.1083/jcb.200706015openalex-snapshot
Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis
inferredcites →https://doi.org/10.1083/jcb.200706189openalex-snapshot
Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate
inferredcites →https://doi.org/10.1093/carcin/bgm019openalex-snapshot
A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy
inferredcites →https://doi.org/10.1093/carcin/bgm066openalex-snapshot
Haploinsufficiency of the cdc2l gene contributes to skin cancer development in mice
inferredcites →https://doi.org/10.1093/emboj/20.23.6637openalex-snapshot
Wide spectrum of tumors in knock‐in mice carrying a Cdk4 protein insensitive to INK4 inhibitors
inferredcites →https://doi.org/10.1093/emboj/cdg482openalex-snapshot
Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells
inferredcites →https://doi.org/10.1101/gad.1272305openalex-snapshot
p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity
inferredcites →https://doi.org/10.1101/gad.1556607openalex-snapshot
Discovery of an oncogenic activity in p27 Kip1 that causes stem cell expansion and a multiple tumor phenotype
inferredcites →https://doi.org/10.1101/gad.1564807openalex-snapshot
Synchronicity: policing multiple aspects of gene expression by Ctk1: Figure 1.
inferredcites →https://doi.org/10.1101/gad.7.8.1572openalex-snapshot
Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation.
inferredcites →https://doi.org/10.1101/gad.8.1.9openalex-snapshot
p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest.
inferredcites →https://doi.org/10.1101/gad.8.24.2939openalex-snapshot
Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function.
inferredcites →https://doi.org/10.1101/gad.9.6.639openalex-snapshot
Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution.
inferredcites →https://doi.org/10.1101/gad.9.6.650openalex-snapshot
p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene.
inferredcites →https://doi.org/10.1111/j.1365-2958.2007.05914.xopenalex-snapshot
Pho85, a multifunctional cyclin‐dependent protein kinase in budding yeast
inferredcites →https://doi.org/10.1126/science.1140735openalex-snapshot
An Oncogene-Induced DNA Damage Model for Cancer Development
inferredcites →https://doi.org/10.1126/science.183.4120.46openalex-snapshot
Genetic Control of the Cell Division Cycle in Yeast
inferredcites →https://doi.org/10.1126/science.274.5285.246openalex-snapshot
Identification of a Human Mitotic Checkpoint Gene: hsMAD2
inferredcites →https://doi.org/10.1126/science.287.5459.1804openalex-snapshot
Hematopoietic Stem Cell Quiescence Maintained by p21 cip1/waf1
inferredcites →https://doi.org/10.1126/science.8266103openalex-snapshot
Distinct Roles for Cyclin-Dependent Kinases in Cell Cycle Control
inferredcites →https://doi.org/10.1128/mcb.18.2.753openalex-snapshot
Functional Inactivation of the Retinoblastoma Protein Requires Sequential Modification by at Least Two Distinct Cyclin-cdk Complexes
inferredcites →https://doi.org/10.1128/mcb.19.10.7011openalex-snapshot
Targeted Disruption of CDK4 Delays Cell Cycle Entry with Enhanced p27 Kip1 Activity
inferredcites →https://doi.org/10.1128/mcb.22.2.644-656.2002openalex-snapshot
Germ Line Transmission of the Cdk4R24C Mutation Facilitates Tumorigenesis and Escape from Cellular Senescence
inferredcites →https://doi.org/10.1128/mcb.24.17.7538-7547.2004openalex-snapshot
Lack of Cyclin-Dependent Kinase 4 Inhibits c- myc Tumorigenic Activities in Epithelial Tissues
inferredcites →https://doi.org/10.1128/mcb.24.8.3188-3197.2004openalex-snapshot
Failure To Proliferate and Mitotic Arrest of CDK11p110/p58-Null Mutant Mice at the Blastocyst Stage of Embryonic Cell Development
inferredcites →https://doi.org/10.1128/mcb.26.7.2736-2745.2006openalex-snapshot
Identification and Characterization of the CDK12/Cyclin L1 Complex Involved in Alternative Splicing Regulation
inferredcites →https://doi.org/10.1158/0008-5472.can-03-3119openalex-snapshot
Slippage of Mitotic Arrest and Enhanced Tumor Development in Mice with BubR1 Haploinsufficiency
inferredcites →https://doi.org/10.1158/0008-5472.can-04-4195openalex-snapshot
Cooperation between Cdk4 and p27kip1 in Tumor Development: A Preclinical Model to Evaluate Cell Cycle Inhibitors with Therapeutic Activity
inferredcites →https://doi.org/10.1158/0008-5472.can-05-2639openalex-snapshot
Cyclin-Dependent Kinase 4 Expression Is Essential for Neu-Induced Breast Tumorigenesis
inferredcites →https://doi.org/10.1158/0008-5472.can-06-4517openalex-snapshot
p18 Ink4c Collaborates with Men1 to Constrain Lung Stem Cell Expansion and Suppress Non–Small-Cell Lung Cancers
inferredcites →https://doi.org/10.1158/0008-5472.can-07-2266openalex-snapshot
Aneuploidy: Instigator and Inhibitor of Tumorigenesis
inferredcites →https://doi.org/10.1182/blood-2005-02-0685openalex-snapshot
Hematopoietic stem cell exhaustion impacted by p18INK4C and p21Cip1/Waf1 in opposite manners
inferredcites →https://doi.org/10.1182/blood-2006-10-054247openalex-snapshot
Checkpoint-apoptosis uncoupling in human and mouse embryonic stem cells: a source of karyotpic instability
inferredcites →https://doi.org/10.1200/jco.2005.03.7689openalex-snapshot
Cyclin-Dependent Kinase Pathways As Targets for Cancer Treatment
inferredcites →https://doi.org/10.1210/en.143.8.3001openalex-snapshot
Pituitary Hypoplasia and Lactotroph Dysfunction in Mice Deficient for Cyclin-Dependent Kinase-4
inferredcites →https://doi.org/10.1242/dev.024919openalex-snapshot
Genetic substitution of Cdk1 by Cdk2 leads to embryonic lethality and loss of meiotic function of Cdk2
inferredcites →https://doi.org/10.1242/jcs.007963openalex-snapshot
CDK11p58 is required for the maintenance of sister chromatid cohesion
inferredcites →https://doi.org/10.1242/jcs.02718openalex-snapshot
Secrets of a double agent: CDK7 in cell-cycle control and transcription
inferredcites →https://doi.org/10.1242/jcs.1989.supplement_12.12openalex-snapshot
Control of G2 delay by the RAD9 gene of Saccharomyces cerevisiae
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.3919590openalex-extracted
The Effect of the Combined Action of Roscovitine and Paclitaxel on the Apoptotic and Cell Cycle Regulatory Mechanisms in Colon and Anaplastic Thyroid Cancer Cells
inferred← citeshttps://doi.org/10.2139/ssrn.4765196openalex-extracted
Discovery and Preclinical Evaluations of Tqb3616, a Novel Cdk4-Biased Inhibitor
inferred← citeshttps://doi.org/10.2139/ssrn.4814175openalex-extracted
Discovery of Colchicine Aryne Cyclo-Adduct as a Potent Molecule for the Abrogation of Epithelial to Mesenchymal Transition Via Modulating Cell Cycle Regulatory Cdk-2 and Cdk-4 Kinases
inferred← citeshttps://doi.org/10.1001/jamanetworkopen.2020.20312openalex-snapshot
Association of Cyclin-Dependent Kinases 4 and 6 Inhibitors With Survival in Patients With Hormone Receptor–Positive Metastatic Breast Cancer
inferred← citeshttps://doi.org/10.1002/0471142727.mb2806s111openalex-snapshot
Assaying Cell Cycle Status Using Flow Cytometry
inferred← citeshttps://doi.org/10.1002/1873-3468.13721openalex-snapshot
Cyclin‐dependent kinase 4 inhibits the translational repressor 4E‐BP1 to promote cap‐dependent translation during mitosis–G1 transition
inferred← citeshttps://doi.org/10.1002/1873-3468.13867openalex-snapshot
Restriction point regulation at the crossroads between quiescence and cell proliferation
inferred← citeshttps://doi.org/10.1002/1878-0261.12148openalex-snapshot
Molecular profiling and combinatorial activity of CCT 068127: a potent CDK 2 and CDK 9 inhibitor
inferred← citeshttps://doi.org/10.1002/1878-0261.12202openalex-snapshot
ANP 32E induces tumorigenesis of triple‐negative breast cancer cells by upregulating E2F1
inferred← citeshttps://doi.org/10.1002/1878-0261.13020openalex-snapshot
DDRugging glioblastoma: understanding and targeting the DNA damage response to improve future therapies
inferred← citeshttps://doi.org/10.1002/1878-0261.13125openalex-snapshot
Lung cancer cells expressing a shortened CDK16 3′UTR escape senescence through impaired miR‐485‐5p targeting
inferred← citeshttps://doi.org/10.1002/1878-0261.13268openalex-snapshot
Cellular senescence and the tumour microenvironment
inferred← citeshttps://doi.org/10.1002/1878-0261.70290openalex-snapshot
Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation
inferred← citeshttps://doi.org/10.1002/2211-5463.12206openalex-snapshot
The G2 checkpoint—a node‐based molecular switch
inferred← citeshttps://doi.org/10.1002/2211-5463.13127openalex-snapshot
High expression of SPP1 in patients with chronic obstructive pulmonary disease (COPD) is correlated with increased risk of lung cancer
inferred← citeshttps://doi.org/10.1002/2211-5463.13306openalex-snapshot
Overexpression of cyclin‐dependent kinase 1 in esophageal squamous cell carcinoma and its clinical significance
inferred← citeshttps://doi.org/10.1002/9780470015902.a0001364.pub3openalex-snapshot
Cell Cycle: Regulation by Cyclins
inferred← citeshttps://doi.org/10.1002/9780470015902.a0002571.pub2openalex-snapshot
Cell Cycle Analysis by Flow Cytometry
inferred← citeshttps://doi.org/10.1002/9781118657072.ch4openalex-snapshot
Protein Biosynthesis, Modifications and Degradation
inferred← citeshttps://doi.org/10.1002/9781118707449.ch8openalex-snapshot
Perspectives in Evo‐Devo of the Vertebrate Brain
inferred← citeshttps://doi.org/10.1002/9781118742952.ch45openalex-snapshot
Metal‐Based Indolobenzazepines and Indoloquinolines: From Moderate CDK Inhibitors to Potential Antitumor Drugs
inferred← citeshttps://doi.org/10.1002/9781119000822.hfcm062openalex-snapshot
Endocrine Therapy for Hormone Receptor‐Positive Breast Cancer
inferred← citeshttps://doi.org/10.1002/9781119000822.hfcm062.pub2openalex-snapshot
Endocrine Therapy for Hormone Receptor‐Positive Breast Cancer
inferred← citeshttps://doi.org/10.1002/9783527633470.ch10openalex-snapshot
Cellular Protein Kinases as Antiviral Targets
inferred← citeshttps://doi.org/10.1002/9783527675401.ch15openalex-snapshot
Protein Kinases as Suitable Targets for Combating Eimeria spp
inferred← citeshttps://doi.org/10.1002/9783527826872.ch9openalex-snapshot
The Discovery of Kisqali ® (Ribociclib): A CDK 4/6 Inhibitor for the Treatment of HR +/ HER 2− Advanced Breast Cancer
inferred← citeshttps://doi.org/10.1002/adbi.202000307openalex-snapshot
Blue Light‐Operated CRISPR/Cas13b‐Mediated mRNA Knockdown (Lockdown)
inferred← citeshttps://doi.org/10.1002/adma.202312488openalex-snapshot
A Nanoscale Trans‐Platinum(II)‐Based Supramolecular Coordination Self‐Assembly with a Distinct Anticancer Mechanism
inferred← citeshttps://doi.org/10.1002/adom.202300850openalex-snapshot
Peptide‐Modified AIEgen Probe for Selective Imaging and Killing of Drug‐Resistant Cancer Cells Based on Cell‐Cycle‐Dependent Uptake
inferred← citeshttps://doi.org/10.1002/advs.201903630openalex-snapshot
LncRNA UCA1 Antagonizes Arsenic‐Induced Cell Cycle Arrest through Destabilizing EZH2 and Facilitating NFATc2 Expression
inferred← citeshttps://doi.org/10.1002/advs.202301088openalex-snapshot
Inhibition of CDK1 Overcomes Oxaliplatin Resistance by Regulating ACSL4‐mediated Ferroptosis in Colorectal Cancer
inferred← citeshttps://doi.org/10.1002/advs.202303009openalex-snapshot
Arf1 GTPase Regulates Golgi‐Dependent G2/M Transition and Spindle Organization in Oocyte Meiosis
inferred← citeshttps://doi.org/10.1002/advs.202411834openalex-snapshot
N4‐Acetylcytidine‐Mediated CD2BP2‐DT Drives YBX1 Phase Separation to Stabilize CDK1 and Promote Breast Cancer Progression
inferred← citeshttps://doi.org/10.1002/advs.202416687openalex-snapshot
Phosphorylation‐Dependent Stabilization of Collaborator of ARF (CARF) Suppresses Lymphoma Cell Proliferation
inferred← citeshttps://doi.org/10.1002/advs.77920openalex-snapshot
Tracking CDK1 Dynamics With a Novel Biosensor Mouse and Clinical Cohorts to Predict CDK4/6 Inhibitor Sensitivity in ER+ Breast Cancer
inferred← citeshttps://doi.org/10.1002/ajoc.202100036openalex-snapshot
New Cysteine Covalent Modification Strategies Enable Advancement of Proteome‐wide Selectivity of Kinase Modulators
inferred← citeshttps://doi.org/10.1002/ange.201906321openalex-snapshot
A Photoaffinity Displacement Assay and Probes to Study the Cyclin‐Dependent Kinase Family
inferred← citeshttps://doi.org/10.1002/ange.202513542openalex-snapshot
Fulcrum Occupancy–Leverage Perturbation Strategy Enables Rapid Discovery of Potent CDK2–Cyclin A2 Interaction Inhibitors
inferred← citeshttps://doi.org/10.1002/anie.201906321openalex-snapshot
A Photoaffinity Displacement Assay and Probes to Study the Cyclin‐Dependent Kinase Family
inferred← citeshttps://doi.org/10.1002/anie.202513542openalex-snapshot
Fulcrum Occupancy–Leverage Perturbation Strategy Enables Rapid Discovery of Potent CDK2–Cyclin A2 Interaction Inhibitors
inferred← citeshttps://doi.org/10.1002/app.71377openalex-snapshot
Proto‐Panic Modulation by Caffeine‐Proteinoid Complexes
inferred← citeshttps://doi.org/10.1002/ardp.201100383openalex-snapshot
2′‐Chloro‐4′‐aminoflavone Derivatives Selectively Targeting Hepatocarcinoma Cells: Convenient Synthetic Process, G2/M Cell Cycle Arrest and Apoptosis Triggers
inferred← citeshttps://doi.org/10.1002/ardp.201700381openalex-snapshot
Design, synthesis, and molecular docking study of 3H‐imidazole[4,5‐c]pyridine derivatives as CDK2 inhibitors
inferred← citeshttps://doi.org/10.1002/ardp.202200367openalex-snapshot
Synthetic flavagline derivative 1‐chloroacetylrocaglaol promotes apoptosis in K562 erythroleukemia cells through miR‐17‐92 cluster genes
inferred← citeshttps://doi.org/10.1002/ardp.202400889openalex-snapshot
New potent N‐hydroxycinnamamide‐based histone deacetylase inhibitors suppress proliferation and trigger apoptosis in THP‐1 leukaemia cells
inferred← citeshttps://doi.org/10.1002/bab.70093openalex-snapshot
Preliminary Assessment of Cytotoxic Effects of Murraya koenigii Toluene Extracts on PA1 Cells via LC‐MS, In Vitro, and In Silico Approaches
inferred← citeshttps://doi.org/10.1002/bab.70137openalex-snapshot
N ‐3 PUFAs Enhancing Chemotherapy Efficacy in Acute Myeloid Leukemia While Safeguarding Healthy Cells
inferred← citeshttps://doi.org/10.1002/bdrc.21060openalex-snapshot
The chondrocytic journey in endochondral bone growth and skeletal dysplasia
inferred← citeshttps://doi.org/10.1002/bies.201400040openalex-snapshot
Preparing a cell for nuclear envelope breakdown: Spatio‐temporal control of phosphorylation during mitotic entry
inferred← citeshttps://doi.org/10.1002/bies.201800183openalex-snapshot
Ribosomal Proteins Control Tumor Suppressor Pathways in Response to Nucleolar Stress
inferred← citeshttps://doi.org/10.1002/bies.202000105openalex-snapshot
CHRONOCRISIS: When Cell Cycle Asynchrony Generates DNA Damage in Polyploid Cells
inferred← citeshttps://doi.org/10.1002/bies.202200150openalex-snapshot
Cell growth and the cell cycle: New insights about persistent questions
inferred← citeshttps://doi.org/10.1002/biot.201600531openalex-snapshot
Targeting Conformational Activation of CDK2 Kinase
inferred← citeshttps://doi.org/10.1002/bkcs.11280openalex-snapshot
Receptor‐guided 3D ‐Quantitative Structure–Activity Relationship and Docking Studies of 6‐Substituted 2‐Arylaminopurines as CDK2 Kinase Inhibitors
inferred← citeshttps://doi.org/10.1002/bkcs.12204openalex-snapshot
Synthesis and Evaluation of a 3, 4‐dihydro‐2H ‐benzoxazine Derivative as a Potent CDK9 Inhibitor for Anticancer Therapy
inferred← citeshttps://doi.org/10.1002/cam4.1263openalex-snapshot
BTG2 is a tumor suppressor gene upregulated by p53 and PTEN in human bladder carcinoma cells
inferred← citeshttps://doi.org/10.1002/cam4.2152openalex-snapshot
Prognostic role of cyclin D2/D3 in multiple human malignant neoplasms: A systematic review and meta‐analysis
inferred← citeshttps://doi.org/10.1002/cam4.7249openalex-snapshot
Abemaciclib plus endocrine therapy versus chemotherapy after progression on prior palbociclib in HR+/HER2‐ metastatic breast cancer: A single center real‐world study in China
inferred← citeshttps://doi.org/10.1002/cbdv.71267openalex-snapshot
Dual‐Targeting Strategy in Cancer Therapy: The Emerging Role of Pyrrolopyrimidine Scaffolds
inferred← citeshttps://doi.org/10.1002/cbf.70177openalex-snapshot
Synergistic Antitumor Potential of Propolis With 6‑Mercaptopurine and 5‑Fluorouracil
inferred← citeshttps://doi.org/10.1002/cbic.200900729openalex-snapshot
Cell‐Cycle Markers and Biosensors
inferred← citeshttps://doi.org/10.1002/cbic.201402318openalex-snapshot
Fluorescent Protein Biosensor for Probing CDK/Cyclin Activity in vitro and in Living Cells
inferred← citeshttps://doi.org/10.1002/cbic.202000381openalex-snapshot
Morphological Profiling Identifies a Common Mode of Action for Small Molecules with Different Targets
inferred← citeshttps://doi.org/10.1002/cbin.11203openalex-snapshot
Inherent control of hepatocyte proliferation after subtotal liver resection
inferred← citeshttps://doi.org/10.1002/chem.201003535openalex-snapshot
Probing the Role of the Linker in Ferrocene–ATP Conjugates: Monitoring Protein Kinase Catalyzed Phosphorylations Electrochemically
inferred← citeshttps://doi.org/10.1002/chem.201203667openalex-snapshot
Total Synthesis and Biological Evaluation of Grassypeptolide A
inferred← citeshttps://doi.org/10.1002/chem.201301389openalex-snapshot
Ruthenium–Arene–β‐Carboline Complexes as Potent Inhibitors of Cyclin‐Dependent Kinase 1: Synthesis, Characterization and Anticancer Mechanism Studies
inferred← citeshttps://doi.org/10.1002/cjoc.201300420openalex-snapshot
Design, Synthesis and Preliminary Biological Evaluation of Purine‐2,6‐diamine Derivatives as Cyclin‐dependent Kinase (CDK) Inhibitors
inferred← citeshttps://doi.org/10.1002/cmdc.201000157openalex-snapshot
Inhibition of Eimeria tenella CDK‐Related Kinase 2: From Target Identification to Lead Compounds
inferred← citeshttps://doi.org/10.1002/cmdc.201100276openalex-snapshot
Synthesis and Anticancer Activity of the (R,S)‐Benzofused 1,5‐Oxathiepine Moiety Tethered to Purines through Alkylidenoxy Linkers
inferred← citeshttps://doi.org/10.1002/cmdc.201600108openalex-snapshot
Synthesis and Biological Evaluation of N2‐Substituted 2,4‐Diamino‐6‐cyclohexylmethoxy‐5‐nitrosopyrimidines and Related 5‐Cyano‐NNO‐azoxy Derivatives as Cyclin‐Dependent Kinase 2 (CDK2) Inhibitors
inferred← citeshttps://doi.org/10.1002/cmdc.202200064openalex-snapshot
2‐Amino‐4‐aryl‐5‐oxo‐4,5‐dihydropyrano[3,2‐c]chromene‐3‐carbonitriles with Microtubule‐Disruptive, Centrosome‐Declustering, and Antiangiogenic Effects in vitro and in vivo
inferred← citeshttps://doi.org/10.1002/cncr.32931openalex-snapshot
Therapy after cyclin‐dependent kinase inhibition in metastatic hormone receptor‐positive breast cancer: Resistance mechanisms and novel treatment strategies
inferred← citeshttps://doi.org/10.1002/cncr.70363openalex-snapshot
Poor clinical outcomes and immunoevasive contexture in gastric cancer patients bearing p16 high phenotype
inferred← citeshttps://doi.org/10.1002/cpet.21openalex-snapshot
Saccharomyces cerevisiae: A Unicellular Model Genetic Organism of Enduring Importance
inferred← citeshttps://doi.org/10.1002/cphy.c200015openalex-snapshot
Novel Pharmacological Targets for Pulmonary Arterial Hypertension
inferred← citeshttps://doi.org/10.1002/cpt.965openalex-snapshot
Emerging Innovative Therapeutic Approaches Leveraging Cyclin‐Dependent Kinase Inhibitors to Treat Advanced Breast Cancer
inferred← citeshttps://doi.org/10.1002/ctm2.503openalex-snapshot
Oncogenic PAX6 elicits CDK4/6 inhibitor resistance by epigenetically inactivating the LATS2‐Hippo signaling pathway
inferred← citeshttps://doi.org/10.1002/cyto.a.21164openalex-snapshot
Three‐dimensional segmentation of nuclei and mitotic chromosomes for the study of cell divisions in live Drosophila embryos
inferred← citeshttps://doi.org/10.1002/ddr.22163openalex-snapshot
Exploring new quinazolin‐4(3H)‐one derivatives as CDK2 inhibitors: Design, synthesis, and anticancer evaluation
inferred← citeshttps://doi.org/10.1002/ddr.70139openalex-snapshot
Comparative Study of Conventional, Grinding, and Microwave‐Assisted Synthesis of Aminopyrazolones and Diaminopyrazoles: Exploring the Antitumor Activity, Dual CDK‐2/CA IX Inhibition Potential, and Apoptosis Induction
inferred← citeshttps://doi.org/10.1002/dneu.22588openalex-snapshot
Ablation of cdk4 and cdk6 affects proliferation of basal progenitor cells in the developing dorsal and ventral forebrain
inferred← citeshttps://doi.org/10.1002/elsc.70039openalex-snapshot
Menthol and Its Derivatives: Exploring the Medical Application Potential
inferred← citeshttps://doi.org/10.1002/emmm.201201483openalex-snapshot
miR‐10b*, a master inhibitor of the cell cycle, is down‐regulated in human breast tumours
inferred← citeshttps://doi.org/10.1002/gcc.22296openalex-snapshot
A rare mutation in a rare tumor— SMARCB 1‐deficient malignant glomus tumor
inferred← citeshttps://doi.org/10.1002/hep.23225openalex-snapshot
Cyclin‐dependent kinase 1 plays a critical role in DNA replication control during rat liver regeneration†
inferred← citeshttps://doi.org/10.1002/hep.26584openalex-snapshot
Concurrent Deletion of Cyclin E1 and Cyclin-Dependent Kinase 2 in Hepatocytes Inhibits DNA Replication and Liver Regeneration in Mice
inferred← citeshttps://doi.org/10.1002/hep.26658openalex-snapshot
Hierarchy of a Regenerative Cell Cycle: Cyclin E1 Multitasks
inferred← citeshttps://doi.org/10.1002/hep.30613openalex-snapshot
Lnc‐UCID Promotes G1/S Transition and Hepatoma Growth by Preventing DHX9‐Mediated CDK6 Down‐regulation
inferred← citeshttps://doi.org/10.1002/ijc.25255openalex-snapshot
The antitumor activity of the fungicide ciclopirox
inferred← citeshttps://doi.org/10.1002/ijc.25916openalex-snapshot
Kinesin 18A expression: Clinical relevance to colorectal cancer progression
inferred← citeshttps://doi.org/10.1002/ijc.28521openalex-snapshot
The natural anticancer compound rocaglamide selectively inhibits the G1-S-phase transition in cancer cells through the ATM/ATR-mediated Chk1/2 cell cycle checkpoints
inferred← citeshttps://doi.org/10.1002/ijc.29013openalex-snapshot
Molecular mechanisms and anti‐cancer aspects of the medicinal phytochemicals rocaglamides (=flavaglines)
inferred← citeshttps://doi.org/10.1002/ijc.29560openalex-snapshot
The DACH/EYA/SIX gene network and its role in tumor initiation and progression
inferred← citeshttps://doi.org/10.1002/ijc.31173openalex-snapshot
RETRACTED: YY1 suppresses proliferation and migration of pancreatic ductal adenocarcinoma by regulating the CDKN3/MdM2/P53/P21 signaling pathway
inferred← citeshttps://doi.org/10.1002/ijc.32166openalex-snapshot
X chromosome‐linked long noncoding RNA lnc‐XLEC1 regulates c‐Myc‐dependent cell growth by collaborating with MBP‐1 in endometrial cancer
inferred← citeshttps://doi.org/10.1002/ijc.32831openalex-snapshot
The transcription factor FLI1 promotes cancer progression by affecting cell cycle regulation
inferred← citeshttps://doi.org/10.1002/ijc.34288openalex-snapshot
Out of the cycle: Impact of cell cycle aberrations on cancer metabolism and metastasis
inferred← citeshttps://doi.org/10.1002/ijc.70442openalex-snapshot
Cyclin‐dependent kinases as therapeutic targets in cancer: Recent advances, challenges, and opportunities
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2021.tb00182.xopenalex-snapshot
Novel Pharmacological Targets for Pulmonary Arterial Hypertension
inferred← citeshttps://doi.org/10.1002/jbt.20415openalex-snapshot
Off‐target immune cell toxicity caused by AG‐012986, a pan‐CDK inhibitor, is associated with inhibition of p38 MAPK phosphorylation
inferred← citeshttps://doi.org/10.1002/jbt.23206openalex-snapshot
Betulinic acid: A natural promising anticancer drug, current situation, and future perspectives
inferred← citeshttps://doi.org/10.1002/jcb.23024openalex-snapshot
Interference with ER‐α enhances the therapeutic efficacy of the selective CDK inhibitor roscovitine towards ER‐positive breast cancer cells
inferred← citeshttps://doi.org/10.1002/jcb.25754openalex-snapshot
Oncogenic Actions of SKP2 Involves Deregulation of CDK1 Turnover Mediated by FOXM1
inferred← citeshttps://doi.org/10.1002/jcb.26515openalex-snapshot
The molecular basis of cytotoxicity of α‐spinasterol from Ganoderma resinaceum: Induction of apoptosis and overexpression of p53 in breast and ovarian cancer cell lines
inferred← citeshttps://doi.org/10.1002/jcb.28056openalex-snapshot
MKL1/miR34a/FOXP3 axis regulates cell proliferation in gastric cancer
inferred← citeshttps://doi.org/10.1002/jcb.28177openalex-snapshot
A new method for excavating feature lncRNA in lung adenocarcinoma based on pathway crosstalk analysis
inferred← citeshttps://doi.org/10.1002/jcb.29477openalex-snapshot
SNHG16 as the miRNA let‐7b‐5p sponge facilitates the G2/M and epithelial‐mesenchymal transition by regulating CDC25B and HMGA2 expression in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1002/jcb.29921openalex-snapshot
Targeting cyclin‐dependent kinase 6 by vanillin inhibits proliferation of breast and lung cancer cells: Combined computational and biochemical studies
inferred← citeshttps://doi.org/10.1002/jcla.23298openalex-snapshot
Upregulation of cyclin D1 can act as an independent prognostic marker for longer survival time in human nasopharyngeal carcinoma
inferred← citeshttps://doi.org/10.1002/jcp.22089openalex-snapshot
RETRACTED: Sequential loss of cell cycle checkpoint control contributes to malignant transformation of murine embryonic fibroblasts induced by 20‐methylcholanthrene
inferred← citeshttps://doi.org/10.1002/jcp.22426openalex-snapshot
Whether to target single or multiple CDKs for therapy? That is the question
inferred← citeshttps://doi.org/10.1002/jcp.24107openalex-snapshot
Dissecting Pin1 and phospho‐pRb regulation
inferred← citeshttps://doi.org/10.1002/jcp.25913openalex-snapshot
Rapamycin attenuates BAFF‐extended proliferation and survival via disruption of mTORC1/2 signaling in normal and neoplastic B‐lymphoid cells
inferred← citeshttps://doi.org/10.1002/jcp.26067openalex-snapshot
Ptn functions downstream of C/EBPβ to mediate the effects of cAMP on uterine stromal cell differentiation through targeting Hand2 in response to progesterone
inferred← citeshttps://doi.org/10.1002/jcp.26586openalex-snapshot
Human hepatocellular carcinoma: Protection by melatonin
inferred← citeshttps://doi.org/10.1002/jcp.27288openalex-snapshot
MicroRNA‐133b suppresses bladder cancer malignancy by targeting TAGLN2‐mediated cell cycle
inferred← citeshttps://doi.org/10.1002/jcp.28021openalex-snapshot
Prognostic and clinicopathological significance of Cks1 in cancer: Evidence from a meta‐analysis
inferred← citeshttps://doi.org/10.1002/jcp.28557openalex-snapshot
NEAT1 promotes colon cancer progression through sponging miR‐495‐3p and activating CDK6 in vitro and in vivo
inferred← citeshttps://doi.org/10.1002/jcp.28597openalex-snapshot
G Protein γ subunit 7 loss contributes to progression of clear cell renal cell carcinoma
inferred← citeshttps://doi.org/10.1002/jcp.29528openalex-snapshot
Novel insights into Dhh signaling in antler chondrocyte proliferation and differentiation: Involvement of Foxa
inferred← citeshttps://doi.org/10.1002/jcp.29676openalex-snapshot
RETRACTED: RFC2, a direct target of miR‐744, modulates the cell cycle and promotes the proliferation of CRC cells
inferred← citeshttps://doi.org/10.1002/jcp.31501openalex-snapshot
RRM2 Is a Putative Biomarker and Promotes Bladder Cancer Progression via PI3K/AKT/mTOR Pathway
inferred← citeshttps://doi.org/10.1002/jcp.31516openalex-snapshot
KIF18A Is a Novel Target of JNK1/c‐Jun Signaling Pathway Involved in Cervical Tumorigenesis
inferred← citeshttps://doi.org/10.1002/jez.b.23143openalex-snapshot
Distinct patterns of gene expression during regeneration and asexual reproduction in the annelid Pristina leidyi
inferred← citeshttps://doi.org/10.1002/jhet.2147openalex-snapshot
The Identification of a Novel Highly Condensed Pentacyclic Heteroaromatic Ring System 1,3,5,5b,6,8,10,10b‐Octaazacyclopenta[h,i]Aceanthrylene and its Application in the Synthesis of 5,7‐Substituted Pyrazolo[4,3‐ d ]Pyrimidines
inferred← citeshttps://doi.org/10.1002/jlb.2ru1021-573ropenalex-snapshot
A curious case of cyclin-dependent kinases in neutrophils
inferred← citeshttps://doi.org/10.1002/jmr.2216openalex-snapshot
Exploring the selectivity of a ligand complex with CDK2/CDK1: a molecular dynamics simulation approach
inferred← citeshttps://doi.org/10.1002/jnr.23312openalex-snapshot
Upregulation of SYF2 is associated with neuronal apoptosis caused by reactive astrogliosis to neuroinflammation
inferred← citeshttps://doi.org/10.1002/jsfa.8719openalex-snapshot
Updating the research on the chemopreventive and therapeutic role of the peptide lunasin
inferred← citeshttps://doi.org/10.1002/jso.21999openalex-snapshot
Epigallocatechin‐3‐gallate induces growth inhibition and apoptosis of human anaplastic thyroid carcinoma cells through suppression of EGFR/ERK pathway and cyclin B1/CDK1 complex
inferred← citeshttps://doi.org/10.1002/mabi.202100450openalex-snapshot
Studying Activated Fibroblast Phenotypes and Fibrosis‐Linked Mechanosensing Using 3D Biomimetic Models
inferred← citeshttps://doi.org/10.1002/mc.20621openalex-snapshot
Epigenetic silencing of cell cycle regulatory genes during 3‐methylcholanthrene and diethylnitrosamine‐induced multistep rat lung cancer
inferred← citeshttps://doi.org/10.1002/mc.21982openalex-snapshot
Cell cycle‐dependent expression of p42.3 promotes mitotic progression in malignant transformed cells
inferred← citeshttps://doi.org/10.1002/mc.22349openalex-snapshot
Knockdown of EHF inhibited the proliferation, invasion and tumorigenesis of ovarian cancer cells
inferred← citeshttps://doi.org/10.1002/mc.22735openalex-snapshot
Molecular insights into the transcriptional regulatory role of thyroid hormones in ovarian cancer
inferred← citeshttps://doi.org/10.1002/mc.23046openalex-snapshot
DNA methylome and transcriptome alterations and cancer prevention by triterpenoid ursolic acid in UVB‐induced skin tumor in mice
inferred← citeshttps://doi.org/10.1002/mc.23290openalex-snapshot
USP39 mediates p21‐dependent proliferation and neoplasia of colon cancer cells by regulating the p53/p21/CDC2/cyclin B1 axis
inferred← citeshttps://doi.org/10.1002/mc.23611openalex-snapshot
EEF1E1 promotes glioma proliferation by regulating cell cycle through PTEN/AKT signaling pathway
inferred← citeshttps://doi.org/10.1002/mc.23811openalex-snapshot
ROR2 promotes cell cycle progression and cell proliferation through the PI3K/AKT signaling pathway in gastric cancer
inferred← citeshttps://doi.org/10.1002/mc.70066openalex-snapshot
Purvalanol A Exerts Anti‐Hepatocellular Carcinoma Activity by Activating the p53 Pathway
inferred← citeshttps://doi.org/10.1002/mco2.136openalex-snapshot
In vivo visualization of fluorescence reflecting CDK4 activity in a breast cancer mouse model
inferred← citeshttps://doi.org/10.1002/mco2.254openalex-snapshot
Repurposing clinically available drugs and therapies for pathogenic targets to combat SARS‐CoV‐2
inferred← citeshttps://doi.org/10.1002/mco2.70536openalex-snapshot
Protein O‐GlcNAcylation in Health and Diseases
inferred← citeshttps://doi.org/10.1002/med.21769openalex-snapshot
How selective are clinical CDK4/6 inhibitors?
inferred← citeshttps://doi.org/10.1002/mgg3.626openalex-snapshot
CDK6 3'UTR polymorphisms alter the susceptibility to cervical cancer among Uyghur females
inferred← citeshttps://doi.org/10.1002/mnfr.201100128openalex-snapshot
Dicaffeoylquinic acids in Yerba mate (Ilex paraguariensis St. Hilaire) inhibit NF‐κB nucleus translocation in macrophages and induce apoptosis by activating caspases‐8 and ‐3 in human colon cancer cells
inferred← citeshttps://doi.org/10.1002/mnfr.201300136openalex-snapshot
5‐ D emethyltangeretin inhibits human nonsmall cell lung cancer cell growth by inducing G 2/M cell cycle arrest and apoptosis
inferred← citeshttps://doi.org/10.1002/mnfr.201500989openalex-snapshot
Identification of pinostilbene as a major colonic metabolite of pterostilbene and its inhibitory effects on colon cancer cells
inferred← citeshttps://doi.org/10.1002/mog2.56openalex-snapshot
Development of covalent inhibitors: Principle, design, and application in cancer
inferred← citeshttps://doi.org/10.1002/mog2.70openalex-snapshot
The biological essence of synthetic lethality: Bringing new opportunities for cancer therapy
inferred← citeshttps://doi.org/10.1002/nano.202400015openalex-snapshot
Advances in breast cancer research using CRISPR/Cas9 system
inferred← citeshttps://doi.org/10.1002/path.2823openalex-snapshot
Activated oncogenic pathways and therapeutic targets in extranodal nasal‐type NK/T cell lymphoma revealed by gene expression profiling
inferred← citeshttps://doi.org/10.1002/path.2878openalex-snapshot
Basic helix‐loop‐helix transcription factor DEC1 negatively regulates cyclin D1
inferred← citeshttps://doi.org/10.1002/path.4896openalex-snapshot
Palbociclib has antitumour effects on Pten‐deficient endometrial neoplasias
inferred← citeshttps://doi.org/10.1002/path.5097openalex-snapshot
Integrating the DNA damage and protein stress responses during cancer development and treatment
inferred← citeshttps://doi.org/10.1002/path.6351openalex-snapshot
TERT upregulation promotes cell proliferation via degradation of p21 and increases carcinogenic potential
inferred← citeshttps://doi.org/10.1002/pep2.24386openalex-snapshot
Buforins: A Potential Antimicrobial Peptide Explored With Its Anticancer Efficacy‐A Review
inferred← citeshttps://doi.org/10.1002/prot.26729openalex-snapshot
Multiple Functional Protein–Protein Interaction Interfaces Allosterically Regulate ATP ‐Binding in Cyclin‐Dependent Kinase‐1
inferred← citeshttps://doi.org/10.1002/ptr.6573openalex-snapshot
A review on gentisic acid as a plant derived phenolic acid and metabolite of aspirin: Comprehensive pharmacology, toxicology, and some pharmaceutical aspects
inferred← citeshttps://doi.org/10.1002/ptr.6815openalex-snapshot
Recent advances and future directions in anti‐tumor activity of cryptotanshinone: A mechanistic review
inferred← citeshttps://doi.org/10.1002/ptr.7299openalex-snapshot
Zeylenone synergizes with cisplatin in osteosarcoma by enhancing DNA damage, apoptosis, and necrosis via the Hsp90/ AKT / GSK3β and Fanconi anaemia pathway
inferred← citeshttps://doi.org/10.1002/rai2.12120openalex-snapshot
Rapamycin suppresses rheumatoid arthritis fibroblast synovial cell proliferation and induces apoptosis via the AKT/mTORC1 pathway
inferred← citeshttps://doi.org/10.1002/rmv.2530openalex-snapshot
Hijacking and rewiring of host CircRNA/miRNA/mRNA competitive endogenous RNA (ceRNA) regulatory networks by oncoviruses during development of viral cancers
inferred← citeshttps://doi.org/10.1002/slct.201803748openalex-snapshot
A Click Strategy for the Synthesis of Fluorescent Pyrimidinone‐Triazole Hybrids with CDK2 Selectivity in HeLa and A549 Cell Lines
inferred← citeshttps://doi.org/10.1002/slct.202103559openalex-snapshot
Synthesis, Biological Evaluation and In Silico Studies of Some 2‐Substituted Benzoxazole Derivatives as Potential Anticancer Agents to Breast Cancer
inferred← citeshttps://doi.org/10.1002/slct.202301189openalex-snapshot
New Fluoro‐ and Trifluoromethyl‐Substituted Trimethoxychalcones as Anticancer Agents: Synthesis, Bio‐evaluation, and Computational Studies
inferred← citeshttps://doi.org/10.1002/slct.202500504openalex-snapshot
Mechanisms of Action and Indications of Cyclin‐Dependent Kinase Inhibitors with Benzoheterocycle Scaffolds
inferred← citeshttps://doi.org/10.1002/slct.74034openalex-snapshot
Design, Synthesis, and Mechanistic Understanding of Thioxothiazole Scaffolds as Possible Apoptotic Inducers and CDK2 Inhibitors in Melanoma
inferred← citeshttps://doi.org/10.1002/smll.202007177openalex-snapshot
Nanobiosensor Reports on CDK1 Kinase Activity in Tumor Xenografts in Mice
inferred← citeshttps://doi.org/10.1002/stem.1342openalex-snapshot
Concise Review: Early Embryonic Erythropoiesis: Not so Primitive After All
inferred← citeshttps://doi.org/10.1002/stem.1382openalex-snapshot
Repression of Zeb1 and Hypoxia Cause Sequential Mesenchymal-to-Epithelial Transition and Induction of Aid, Oct4, and Dnmt1, Leading to Immortalization and Multipotential Reprogramming of Fibroblasts in Spheres
inferred← citeshttps://doi.org/10.1002/stem.616openalex-snapshot
Cdk6-Dependent Regulation of G1 Length Controls Adult Neurogenesis
inferred← citeshttps://doi.org/10.1002/tox.22315openalex-snapshot
Effects of structurally different noncoplanar and coplanar PCBs on HELF cell proliferation, cell cycle, and potential molecular mechanisms
inferred← citeshttps://doi.org/10.1002/tox.22395openalex-snapshot
The aflatoxin B1‐fumonisin B1toxicity in BRL‐3A hepatocytes is associated to induction of cytochrome P450 activity and arachidonic acid metabolism
inferred← citeshttps://doi.org/10.1002/wrna.1816openalex-snapshot
Cyclin‐dependent kinases: Masters of the eukaryotic universe
inferred← citeshttps://doi.org/10.1002/wrna.4openalex-snapshot
Posttranscriptional regulation of cancer traits by HuR
inferred← citeshttps://doi.org/10.1002/wsbm.1342openalex-snapshot
Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial
inferred← citeshttps://doi.org/10.1007/7355_2020_97openalex-snapshot
Function, Structure and Topology of Protein Kinases
inferred← citeshttps://doi.org/10.1007/978-0-85729-482-1_3openalex-snapshot
Genetics and Genito-Urinary Cancer
inferred← citeshttps://doi.org/10.1007/978-0-85729-826-3_13openalex-snapshot
Start and Stop Signals of Oocyte Meiotic Maturation
inferred← citeshttps://doi.org/10.1007/978-1-0716-0138-9_15openalex-snapshot
Quantitation of Molecular Pathway Activation Using RNA Sequencing Data
inferred← citeshttps://doi.org/10.1007/978-1-0716-1217-0_11openalex-snapshot
Assaying Cell Cycle Status Using Flow Cytometry
inferred← citeshttps://doi.org/10.1007/978-1-0716-1258-3_3openalex-snapshot
Simultaneous Detection of Four Cell Cycle Phases with Live Fluorescence Imaging
inferred← citeshttps://doi.org/10.1007/978-1-0716-3557-5_16openalex-snapshot
Investigating Heterogeneous Cell-Cycle Progression Using Single-Cell Imaging Approaches
inferred← citeshttps://doi.org/10.1007/978-1-4419-0717-2_13openalex-snapshot
Cell Cycle-Related Kinases
inferred← citeshttps://doi.org/10.1007/978-1-4419-1770-6_1openalex-snapshot
Escape from Cellular Quiescence
inferred← citeshttps://doi.org/10.1007/978-1-4419-1770-6_11openalex-snapshot
Targeting Cyclin-Dependent Kinases for Cancer Therapy
inferred← citeshttps://doi.org/10.1007/978-1-4419-1770-6_2openalex-snapshot
Interplay Between Cyclin-Dependent Kinases and E2F-Dependent Transcription
inferred← citeshttps://doi.org/10.1007/978-1-4419-1770-6_3openalex-snapshot
Regulation of Pre-RC Assembly: A Complex Symphony Orchestrated by CDKs
inferred← citeshttps://doi.org/10.1007/978-1-4419-9863-7_10openalex-snapshot
Cyclins and Cyclin-dependent Kinases
inferred← citeshttps://doi.org/10.1007/978-1-4614-6613-0_13-4openalex-snapshot
Cell Cycle Related Kinases
inferred← citeshttps://doi.org/10.1007/978-1-4614-6613-0_13-5openalex-snapshot
Cell Cycle-Related Kinases
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