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Plant microRNAs as novel immunomodulatory agents

https://doi.org/10.1038/srep25761
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Transfer and functional consequences of dietary microRNAs in vertebrates: Concepts in search of corroboration
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Inhibition of allogeneic T‐cell responses by dendritic cells expressing transduced indoleamine 2,3‐dioxygenase
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Monitoring Innate Immune Recruitment by siRNAs in Mammalian Cells
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Induction of type I interferon by RNA viruses: cellular receptors and their substrates
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A cetyltrimethylammonium bromide-based method to extract low-molecular-weight RNA from polysaccharide-rich plant tissues
inferredcites →https://doi.org/10.1016/j.coi.2012.11.001openalex-snapshot
TLR3 immunity to infection in mice and humans
inferredcites →https://doi.org/10.1016/j.expneurol.2015.04.011openalex-snapshot
The microRNAs Let7c and miR21 are recognized by neuronal Toll-like receptor 7 to restrict dendritic growth of neurons
inferredcites →https://doi.org/10.1016/j.gene.2012.12.009openalex-snapshot
Regulation of the MIR155 host gene in physiological and pathological processes
inferredcites →https://doi.org/10.1016/j.jmb.2005.03.013openalex-snapshot
Induction of Inflammatory Cytokines and Interferon Responses by Double-stranded and Single-stranded siRNAs is Sequence-dependent and Requires Endosomal Localization
inferredcites →https://doi.org/10.1016/j.jmb.2006.09.034openalex-snapshot
Gene Expression Analysis in Blood Cells in Response to Unmodified and 2′-Modified siRNAs Reveals TLR-dependent and Independent Effects
inferredcites →https://doi.org/10.1016/j.jmb.2012.05.006openalex-snapshot
Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure
inferredcites →https://doi.org/10.1016/j.pneurobio.2010.06.005openalex-snapshot
Animal models of multiple sclerosis—Potentials and limitations
inferredcites →https://doi.org/10.1016/j.smim.2003.10.003openalex-snapshot
TLR signaling pathways
inferredcites →https://doi.org/10.1016/j.smim.2011.11.004openalex-snapshot
How the interplay between antigen presenting cells and microbiota tunes host immune responses in the gut
inferredcites →https://doi.org/10.1016/j.tibtech.2015.06.003openalex-snapshot
Dietary delivery: a new avenue for microRNA therapeutics?
inferredcites →https://doi.org/10.1016/j.ymthe.2005.11.002openalex-snapshot
Design of Noninflammatory Synthetic siRNA Mediating Potent Gene Silencing in Vivo
inferredcites →https://doi.org/10.1038/35078107openalex-snapshot
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
inferredcites →https://doi.org/10.1038/cr.2011.158openalex-snapshot
Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA
inferredcites →https://doi.org/10.1038/cr.2012.36openalex-snapshot
Regulation of small RNA stability: methylation and beyond
inferredcites →https://doi.org/10.1038/cr.2014.130openalex-snapshot
Honeysuckle-encoded atypical microRNA2911 directly targets influenza A viruses
inferredcites →https://doi.org/10.1038/cr.2015.26openalex-snapshot
Detection of dietary plant-based small RNAs in animals
inferredcites →https://doi.org/10.1038/nature06765openalex-snapshot
Sequence- and target-independent angiogenesis suppression by siRNA via TLR3
inferredcites →https://doi.org/10.1038/nbt.2737openalex-snapshot
Lack of detectable oral bioavailability of plant microRNAs after feeding in mice
inferredcites →https://doi.org/10.1038/ncomms2857openalex-snapshot
Toll-like receptor 3 recognizes incomplete stem structures in single-stranded viral RNA
inferredcites →https://doi.org/10.1038/ncomms2874openalex-snapshot
High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9–TRIF pathway
inferredcites →https://doi.org/10.1038/ncomms6488openalex-snapshot
Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity
inferredcites →https://doi.org/10.1038/nri2297openalex-snapshot
CCR7 and its ligands: balancing immunity and tolerance
inferredcites →https://doi.org/10.1038/nri2708openalex-snapshot
Physiological and pathological roles for microRNAs in the immune system
inferredcites →https://doi.org/10.1073/pnas.0710779105openalex-snapshot
The TLR3 signaling complex forms by cooperative receptor dimerization
inferredcites →https://doi.org/10.1073/pnas.1202244109openalex-snapshot
Early environments and the ecology of inflammation
inferredcites →https://doi.org/10.1073/pnas.1209414109openalex-snapshot
MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response
inferredcites →https://doi.org/10.1074/jbc.m110.167973openalex-snapshot
Dimerization of Toll-like Receptor 3 (TLR3) Is Required for Ligand Binding
inferredcites →https://doi.org/10.1089/dna.2005.24.614openalex-snapshot
Interferon-β Induction Through Toll-Like Receptor 3 Depends on Double-Stranded RNA Structure
inferredcites →https://doi.org/10.1089/jir.2007.0090openalex-snapshot
Determinants of Cytokine Induction by Small Interfering RNA in Human Peripheral Blood Mononuclear Cells
inferredcites →https://doi.org/10.1089/jir.2014.0034openalex-snapshot
dsRNA-Activation of TLR3 and RLR Signaling: Gene Induction-Dependent and Independent Effects
inferredcites →https://doi.org/10.1095/biolreprod.114.124032openalex-snapshot
Viral Single Stranded RNA Induces a Trophoblast Pro-Inflammatory and Antiviral Response in a TLR8-Dependent and -Independent Manner1
inferredcites →https://doi.org/10.1096/fj.14-260323openalex-snapshot
Noncoding RNAs, cytokines, and inflammation-related diseases
inferredcites →https://doi.org/10.1111/bph.12263openalex-snapshot
Antagonism of histamine H4 receptors exacerbates clinical and pathological signs of experimental autoimmune encephalomyelitis
inferredcites →https://doi.org/10.1126/scienceopenalex-snapshot
Science
inferredcites →https://doi.org/10.1126/science.1140516openalex-snapshot
Signals from chloroplasts converge to regulate nuclear gene expression.
inferredcites →https://doi.org/10.1126/science.1155406openalex-snapshot
Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA
inferredcites →https://doi.org/10.1146/annurev-immunol-020711-075013openalex-snapshot
microRNA Regulation of Inflammatory Responses
inferredcites →https://doi.org/10.1182/blood-2010-04-280156openalex-snapshot
miR-155 and its star-form partner miR-155* cooperatively regulate type I interferon production by human plasmacytoid dendritic cells
inferredcites →https://doi.org/10.1182/blood-2011-02-338004openalex-snapshot
Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes
inferredcites →https://doi.org/10.1182/blood-2011-06-362582openalex-snapshot
TLR3 essentially promotes protective class I–restricted memory CD8+ T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients
inferredcites →https://doi.org/10.1186/1471-2407-11-108openalex-snapshot
Interaction and uptake of exosomes by ovarian cancer cells
inferredcites →https://doi.org/10.1186/s12977-014-0126-4openalex-snapshot
Friend retrovirus drives cytotoxic effectors through Toll-like receptor 3
inferredcites →https://doi.org/10.1186/s13045-015-0111-yopenalex-snapshot
Transfer of microRNAs by extracellular membrane microvesicles: a nascent crosstalk model in tumor pathogenesis, especially tumor cell-microenvironment interactions
inferredcites →https://doi.org/10.1189/jlb.1a1014-519rropenalex-snapshot
Regulation of miR-24, miR-30b, and miR-142-3p during macrophage and dendritic cell differentiation potentiates innate immunity
inferredcites →https://doi.org/10.1261/rna.2340906openalex-snapshot
Induction of the interferon response by siRNA is cell type– and duplex length–dependent
inferredcites →https://doi.org/10.1371/journal.pgen.1004602openalex-snapshot
Trans-kingdom Cross-Talk: Small RNAs on the Move
inferredcites →https://doi.org/10.2174/156652410791317048openalex-snapshot
Small Non-Coding RNAs as Novel Therapeutics
inferredcites →https://doi.org/10.3389/fimmu.2014.00542openalex-snapshot
“Small Talk” in the Innate Immune System via RNA-Containing Extracellular Vesicles
inferredcites →https://doi.org/10.3389/fmed.2015.00047openalex-snapshot
Exosomic microRNAs in the Tumor Microenvironment
inferredcites →https://doi.org/10.3390/ijms140816010openalex-snapshot
Non-Coding RNAs: Multi-Tasking Molecules in the Cell
inferredcites →https://doi.org/10.3402/jev.v3.23743openalex-snapshot
Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell‐free blood
inferredcites →https://doi.org/10.3945/jn.114.196436openalex-snapshot
MicroRNAs Are Absorbed in Biologically Meaningful Amounts from Nutritionally Relevant Doses of Cow Milk and Affect Gene Expression in Peripheral Blood Mononuclear Cells, HEK-293 Kidney Cell Cultures, and Mouse Livers
inferredcites →https://doi.org/10.4049/jimmunol.0901594openalex-snapshot
Immunostimulatory RNA Oligonucleotides Induce an Effective Antitumoral NK Cell Response through the TLR7
inferredcites →https://doi.org/10.4049/jimmunol.0902972openalex-snapshot
Differential IL-17 Production and Mannan Recognition Contribute to Fungal Pathogenicity and Commensalism
inferredcites →https://doi.org/10.4049/jimmunol.1001573openalex-snapshot
MicroRNA-148/152 Impair Innate Response and Antigen Presentation of TLR-Triggered Dendritic Cells by Targeting CaMKIIα
inferredcites →https://doi.org/10.4049/jimmunol.1401893openalex-snapshot
miR-24, miR-30b, and miR-142-3p Regulate Phagocytosis in Myeloid Inflammatory Cells
inferredcites →https://doi.org/10.4049/jimmunol.171.4.1652openalex-snapshot
Cutting Edge: Induced Indoleamine 2,3 Dioxygenase Expression in Dendritic Cell Subsets Suppresses T Cell Clonal Expansion
inferredcites →https://doi.org/10.4161/rna.24909openalex-snapshot
Ineffective delivery of diet-derived microRNAs to recipient animal organisms
inferredcites →https://doi.org/10.4161/rna.25246openalex-snapshot
Real-time quantitative PCR and droplet digital PCR for plant miRNAs in mammalian blood provide little evidence for general uptake of dietary miRNAs

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Olea-Europaea Leaf Exosome-Like Nanovesicles Loaded Hyaluronic Acid/ Tannic Acid Hydrogel Dressing with Dual Effect of 'Defense-Repair' for Treating Skin Photoaging
inferred← citeshttps://doi.org/10.1002/mnfr.201600974openalex-snapshot
The atypical genesis and bioavailability of the plant-based small RNA MIR2911: Bulking up while breaking down
inferred← citeshttps://doi.org/10.1002/stem.2833openalex-snapshot
Cardiomyocyte Maturation Requires TLR3 Activated Nuclear Factor Kappa B
inferred← citeshttps://doi.org/10.1007/978-3-030-63512-1_18openalex-snapshot
Darwinian Medicine: We Evolved to Require Continuing Contact with the Microbiota of the Natural Environment. Evolution Turns the Inevitable into a Necessity
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Effects of Plant Secondary Metabolites on Cardiovascular Diseases Through Non-coding RNAs
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Grapes: A Crop with High Nutraceuticals Genetic Diversity
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Grapes: A Crop with High Nutraceuticals Genetic Diversity
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PhytosRNA therapeutics: Cross-kingdom communication and translational potential of Chinese herbal medicine-derived small RNAs
inferred← citeshttps://doi.org/10.1007/s00425-020-03342-0openalex-snapshot
Computational screening of miRNAs and their targets in leaves of Hypericum spp. by transcriptome-mining: a pilot study
inferred← citeshttps://doi.org/10.1007/s11427-016-0240-4openalex-snapshot
Mesenchymal stem cells-derived exosomal microRNAs contribute to wound inflammation
inferred← citeshttps://doi.org/10.1007/s11427-017-9026-7openalex-snapshot
Plant-derived phosphocholine facilitates cellular uptake of anti-pulmonary fibrotic HJT-sRNA-m7
inferred← citeshttps://doi.org/10.1007/s12033-019-00167-5openalex-snapshot
A Modified In Vitro Transcription Approach to Improve RNA Synthesis and Ribozyme Cleavage Efficiency
inferred← citeshttps://doi.org/10.1007/s12079-022-00705-yopenalex-snapshot
Advances in studies of circulating microRNAs: origination, transportation, and distal target regulation
inferred← citeshttps://doi.org/10.1007/s13105-024-01023-0openalex-snapshot
MicroRNAs from edible plants reach the human gastrointestinal tract and may act as potential regulators of gene expression
inferred← citeshttps://doi.org/10.1016/b978-0-08-100596-5.22722-4openalex-snapshot
Dietary Modulation of the Gut Microbiome—Probing the Role of Small RNAs
inferred← citeshttps://doi.org/10.1016/b978-0-12-815350-5.00012-7openalex-snapshot
MicroRNAs and exosomes in human milk
inferred← citeshttps://doi.org/10.1016/b978-0-443-23891-8.00003-2openalex-snapshot
Extracellular vesicles: unlocking therapeutic potential in regenerative medicine
inferred← citeshttps://doi.org/10.1016/bs.abl.2020.04.002openalex-snapshot
Plant extracellular vesicles: the safe for bioactive compounds
inferred← citeshttps://doi.org/10.1016/j.bbadis.2016.10.024openalex-snapshot
Functional significance of exosomes applied in sepsis: A novel approach to therapy
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115904openalex-snapshot
Plant-derived extracellular vesicles -a novel clinical anti-inflammatory drug carrier worthy of investigation
inferred← citeshttps://doi.org/10.1016/j.compbiomed.2022.105502openalex-snapshot
Unveiling the nature's fruit basket to computationally identify Citrus sinensis csi-mir169–3p as a probable plant miRNA against Reference and Omicron SARS-CoV-2 genome
inferred← citeshttps://doi.org/10.1016/j.coph.2021.07.022openalex-snapshot
MicroRNA: A mediator of diet-induced cardiovascular protection
inferred← citeshttps://doi.org/10.1016/j.eng.2023.09.007openalex-snapshot
Lycium barbarum L.-Derived miR162a Functions on Osteoporosis Through Directly Promoting Osteoblast Formation
inferred← citeshttps://doi.org/10.1016/j.fbio.2020.100796openalex-snapshot
The neglected nutrigenomics of milk: What is the role of inter-species transfer of small non-coding RNA?
inferred← citeshttps://doi.org/10.1016/j.genrep.2021.101089openalex-snapshot
Exploring the MiRnome of Carica papaya: A cross kingdom approach
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.113267openalex-snapshot
The critical role of miRNA in bacterial zoonosis
inferred← citeshttps://doi.org/10.1016/j.jff.2024.106347openalex-snapshot
Study of the microRNA fraction in food waste and other biomasses. Assessment of its antioxidant and anti-inflammatory activity
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2018.08.001openalex-snapshot
Reply to Fromm et al.
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2020.108376openalex-snapshot
Stability and absorption mechanism of typical plant miRNAs in an in vitro gastrointestinal environment: basis for their cross-kingdom nutritional effects
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Olea europaea leaf exosome-like nanovesicles encapsulated in a hyaluronic acid / tannic acid hydrogel dressing with dual “defense-repair” effects for treating skin photoaging
inferred← citeshttps://doi.org/10.1016/j.omtn.2022.12.015openalex-snapshot
Quantitative analysis of miRNAs using SplintR ligase-mediated ligation of complementary-pairing probes enhanced by RNase H (SPLICER)-qPCR
inferred← citeshttps://doi.org/10.1016/j.phrs.2022.106472openalex-snapshot
Therapeutic potential of broccoli-derived extracellular vesicles as nanocarriers of exogenous miRNAs
inferred← citeshttps://doi.org/10.1016/j.phrs.2026.108299openalex-snapshot
From food-medicine homology to clinical potential: Plant-derived vesicle-like nanoparticles for inflammation management
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2021.149531openalex-snapshot
Silver birch pollen-derived microRNAs promote NF-κB-mediated inflammation in human lung cells
inferred← citeshttps://doi.org/10.1016/j.sjbs.2021.01.039openalex-snapshot
Plant-derived xenomiRs and cancer: Cross-kingdom gene regulation
inferred← citeshttps://doi.org/10.1016/j.tifs.2023.04.001openalex-snapshot
Extraction, detection and determination of dietary microRNA: A review
inferred← citeshttps://doi.org/10.1016/j.virusres.2021.198631openalex-snapshot
The role of microRNAs in solving COVID-19 puzzle from infection to therapeutics: A mini-review
inferred← citeshttps://doi.org/10.1016/j.yexcr.2022.113455openalex-snapshot
The potential of Lycium barbarum miR166a in kidney cancer treatment
inferred← citeshttps://doi.org/10.1016/j.ymthe.2026.05.018openalex-snapshot
Plant-derived miRNAs: Cross-kingdom anti-tumor agents and next generation of oral biopharmaceuticals
inferred← citeshttps://doi.org/10.1021/acs.jafc.1c07730openalex-snapshot
Digestion of Plant Dietary miRNAs Starts in the Mouth under the Protection of Coingested Food Components and Plant-Derived Exosome-like Nanoparticles
inferred← citeshttps://doi.org/10.1021/acs.jafc.3c03721openalex-snapshot
The Role of microRNAs in Arsenic-Induced Human Diseases: A Review
inferred← citeshttps://doi.org/10.1021/acs.jafc.3c06104openalex-snapshot
Plant miRNA bol-miR159 Regulates Gut Microbiota Composition in Mice: In Vivo Evidence of the Crosstalk between Plant miRNAs and Intestinal Microbes
inferred← citeshttps://doi.org/10.1021/acs.jafc.3c09097openalex-snapshot
Evidence of Cross-Kingdom Gene Regulation by Plant MicroRNAs and Possible Reasons for Inconsistencies
inferred← citeshttps://doi.org/10.1021/acs.jafc.3c09511openalex-snapshot
Atypical Plant miRNA cal-miR2911: Robust Stability against Food Digestion and Specific Promoting Effect on Bifidobacterium in Mice
inferred← citeshttps://doi.org/10.1021/acs.jafc.4c07283openalex-snapshot
osa-miR168a, a Plant miRNA That Survives the Process of In Vivo Food Digestion, Attenuates Dextran Sulfate Sodium-Induced Colitis in Mice by Oral Administration
inferred← citeshttps://doi.org/10.1038/s41598-019-38932-wopenalex-snapshot
Diff isomiRs: Large-scale detection of differential isomiRs for understanding non-coding regulated stress omics in plants
inferred← citeshttps://doi.org/10.1038/s41598-024-51370-7openalex-snapshot
Yeast strains isolated from fermented beverage produce extracellular vesicles with anti-inflammatory effects
inferred← citeshttps://doi.org/10.1038/s42003-019-0563-7openalex-snapshot
Adipocyte metabolism is improved by TNF receptor-targeting small RNAs identified from dried nuts
inferred← citeshttps://doi.org/10.1039/c9fo00216bopenalex-snapshot
Nutritive implications of dietary microRNAs: facts, controversies, and perspectives
inferred← citeshttps://doi.org/10.1039/d1fo01156aopenalex-snapshot
Cross-kingdom regulation by dietary plant miRNAs: an evidence-based review with recent updates
inferred← citeshttps://doi.org/10.1080/01635581.2018.1526307openalex-snapshot
Induction of Apoptosis in HeLa by Corn Small RNAs
inferred← citeshttps://doi.org/10.1080/08820139.2021.1891094openalex-snapshot
Application of Emerging Plant-Derived Nanoparticles as a Novel Approach for Nano-Drug Delivery Systems
inferred← citeshttps://doi.org/10.1080/14760584.2017.1323636openalex-snapshot
Do microRNAs play a role in the activity of plant-based vaccines?
inferred← citeshttps://doi.org/10.1080/15476286.2021.1885189openalex-snapshot
Exosomes provide unappreciated carrier effects that assist transfers of their miRNAs to targeted cells; I. They are ‘The Elephant in the Room’
inferred← citeshttps://doi.org/10.1093/advances/nmaa095openalex-snapshot
Cross-Kingdom Regulation by Plant microRNAs Provides Novel Insight into Gene Regulation
inferred← citeshttps://doi.org/10.1093/advances/nmy127openalex-snapshot
Dietary microRNA—A Novel Functional Component of Food
inferred← citeshttps://doi.org/10.1093/bib/bbz079openalex-snapshot
Circulating microRNA trafficking and regulation: computational principles and practice
inferred← citeshttps://doi.org/10.1093/jn/nxx024openalex-snapshot
RNase H2-Dependent Polymerase Chain Reaction and Elimination of Confounders in Sample Collection, Storage, and Analysis Strengthen Evidence That microRNAs in Bovine Milk Are Bioavailable in Humans
inferred← citeshttps://doi.org/10.1111/bph.15421openalex-snapshot
Eating microRNAs: pharmacological opportunities for cross‐kingdom regulation and implications in host gene and gut microbiota modulation
inferred← citeshttps://doi.org/10.1128/mbio.03563-21openalex-snapshot
Candida albicans Induces Cross-Kingdom miRNA Trafficking in Human Monocytes To Promote Fungal Growth
inferred← citeshttps://doi.org/10.1146/annurev-animal-020518-115300openalex-snapshot
Milk-Derived Exosomes and Metabolic Regulation
inferred← citeshttps://doi.org/10.1146/annurev-nutr-100225-084130openalex-snapshot
From Food to Function: Cross-Kingdom Transfer and Regulatory Potential of Dietary microRNAs Highlighted by Breast Milk
inferred← citeshttps://doi.org/10.1146/annurev-nutr-122319-035633openalex-snapshot
Roles of Regulatory RNAs in Nutritional Control
inferred← citeshttps://doi.org/10.1152/ajpgi.00160.2019openalex-snapshot
Dietary bovine milk exosomes elicit changes in bacterial communities in C57BL/6 mice
inferred← citeshttps://doi.org/10.1186/s12263-017-0562-6openalex-snapshot
Milk exosomes: beyond dietary microRNAs
inferred← citeshttps://doi.org/10.1186/s12263-017-0563-5openalex-snapshot
Bioavailability of transgenic microRNAs in genetically modified plants
inferred← citeshttps://doi.org/10.1186/s12263-017-0564-4openalex-snapshot
Diet-derived microRNAs: unicorn or silver bullet?
inferred← citeshttps://doi.org/10.1186/s12864-018-5227-3openalex-snapshot
Prediction of plant-derived xenomiRs from plant miRNA sequences using random forest and one-dimensional convolutional neural network models
inferred← citeshttps://doi.org/10.1186/s12865-024-00675-3openalex-snapshot
Role of microRNAs in immunoregulatory functions of epithelial cells
inferred← citeshttps://doi.org/10.1186/s12951-025-03602-9openalex-snapshot
Exploring the bioactivity of MicroRNAs Originated from Plant-derived Exosome-like Nanoparticles (PELNs): current perspectives
inferred← citeshttps://doi.org/10.1186/s12951-026-04484-1openalex-snapshot
Plant-derived nanovesicles: the intelligent nanoplatforms for therapeutics and drug delivery
inferred← citeshttps://doi.org/10.1186/s12967-024-05454-7openalex-snapshot
MicroRNAs and the Mediterranean diet: a nutri-omics perspective for lung cancer
inferred← citeshttps://doi.org/10.1186/s12986-018-0305-8openalex-snapshot
MicroRNAs from plants to animals, do they define a new messenger for communication?
inferred← citeshttps://doi.org/10.1186/s13578-019-0370-3openalex-snapshot
Small RNAs in eucaryotes: new clues for amplifying microRNA benefits
inferred← citeshttps://doi.org/10.1186/s41544-019-0009-xopenalex-snapshot
Extracellular microRNAs initiate immunostimulation via activating toll-like receptor signaling pathways
inferred← citeshttps://doi.org/10.1186/s41544-019-0041-xopenalex-snapshot
MicroRNAs in bovine milk exosomes are bioavailable in humans but do not elicit a robust pro-inflammatory cytokine response
inferred← citeshttps://doi.org/10.1186/s43094-022-00413-9openalex-snapshot
Recent trends in miRNA therapeutics and the application of plant miRNA for prevention and treatment of human diseases
inferred← citeshttps://doi.org/10.1261/rna.058404.116openalex-snapshot
RiboCAT: a new capillary electrophoresis data analysis tool for nucleic acid probing
inferred← citeshttps://doi.org/10.12677/ojns.2025.135108openalex-snapshot
Research and Application of Genomics in Carthamus tinctorius
inferred← citeshttps://doi.org/10.1371/journal.pone.0187519openalex-snapshot
Evidence for plant-derived xenomiRs based on a large-scale analysis of public small RNA sequencing data from human samples
inferred← citeshttps://doi.org/10.1371/journal.pone.0257878openalex-snapshot
Large-scale identification of extracellular plant miRNAs in mammals implicates their dietary intake
inferred← citeshttps://doi.org/10.18632/oncotarget.22346openalex-snapshot
Dietary miR-451 protects erythroid cells from oxidative stress via increasing the activity of Foxo3 pathway
inferred← citeshttps://doi.org/10.21203/rs.3.rs-1740960/v1openalex-snapshot
Lb-miR166a has a potentially positive impact on the treatment of kidney cancer
inferred← citeshttps://doi.org/10.2174/0113816128310724240730072626openalex-snapshot
A New Frontier in Phytotherapy: Harnessing the Therapeutic Power of Medicinal Herb-derived miRNAs
inferred← citeshttps://doi.org/10.2174/2211536608666181203103233openalex-snapshot
Common Variants of the Plant microRNA-168a Exhibit Differing Silencing Efficacy for Human Low-Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1)
inferred← citeshttps://doi.org/10.2174/2211536612666230331083455openalex-snapshot
Instead of Calories, Should We Be Counting our Consumption of Exosomes and MicroRNAs?
inferred← citeshttps://doi.org/10.2174/2211536612666230410094424openalex-snapshot
Small Non-coding RNA in Plants: From Basic Science to Innovative Applications
inferred← citeshttps://doi.org/10.3389/fgene.2021.613197openalex-snapshot
A Timely Review of Cross-Kingdom Regulation of Plant-Derived MicroRNAs
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1255668openalex-snapshot
Progress and challenges of plant-derived nucleic acids as therapeutics in macrophage-mediated RNA therapy
inferred← citeshttps://doi.org/10.3389/fmicb.2017.00768openalex-snapshot
New Insight into Inter-kingdom Communication: Horizontal Transfer of Mobile Small RNAs
inferred← citeshttps://doi.org/10.3389/fmolb.2022.1012359openalex-snapshot
Exogenous miRNAs from Moringa oleifera Lam. recover a dysregulated lipid metabolism
inferred← citeshttps://doi.org/10.3389/fnut.2021.586564openalex-snapshot
Potential Mechanisms Linking Food-Derived MicroRNAs, Gut Microbiota and Intestinal Barrier Functions in the Context of Nutrition and Human Health
inferred← citeshttps://doi.org/10.3389/fnut.2023.1287312openalex-snapshot
miR482f and miR482c-5p from edible plant-derived foods inhibit the expression of pro-inflammatory genes in human THP-1 macrophages
inferred← citeshttps://doi.org/10.3389/fpls.2019.01535openalex-snapshot
A Bioinformatics Approach to Explore MicroRNAs as Tools to Bridge Pathways Between Plants and Animals. Is DNA Damage Response (DDR) a Potential Target Process?
inferred← citeshttps://doi.org/10.3389/fpls.2024.1512047openalex-snapshot
Cross-kingdom regulation of plant microRNAs: potential application in crop improvement and human disease therapeutics
inferred← citeshttps://doi.org/10.3390/antiox11040794openalex-snapshot
Does Plant Breeding for Antioxidant-Rich Foods Have an Impact on Human Health?
inferred← citeshttps://doi.org/10.3390/app12115329openalex-snapshot
A Method to Produce vsiRNAs in Plants with Cross-Kingdom Gene Silencing Capacity
inferred← citeshttps://doi.org/10.3390/app13116656openalex-snapshot
Plant Extracellular Vesicles: Investigating Their Utilization as Beneficial Nutrients in Diet
inferred← citeshttps://doi.org/10.3390/biology14020215openalex-snapshot
Characterization of Exosome-like Nanoparticles from Saffron Tepals and Their Immunostimulatory Activity
inferred← citeshttps://doi.org/10.3390/biom11010087openalex-snapshot
Strawberry-Derived Exosome-Like Nanoparticles Prevent Oxidative Stress in Human Mesenchymal Stromal Cells
inferred← citeshttps://doi.org/10.3390/biomedicines11041053openalex-snapshot
Plant-Derived Exosome-like Nanoparticles for Biomedical Applications and Regenerative Therapy
inferred← citeshttps://doi.org/10.3390/cimb46070443openalex-snapshot
Differential Digestive Stability of Food-Derived microRNAs: The Case of miR-30c-5p and miR-92a-3p in Polyfloral Honey
inferred← citeshttps://doi.org/10.3390/ijms18061191openalex-snapshot
Cross-Kingdom Regulation of Putative miRNAs Derived from Happy Tree in Cancer Pathway: A Systems Biology Approach
inferred← citeshttps://doi.org/10.3390/ijms23147554openalex-snapshot
Extracellular Vesicles—Oral Therapeutics of the Future
inferred← citeshttps://doi.org/10.3390/ijms25031721openalex-snapshot
Plant miR8126-3p and miR8126-5p Decrease Lipid Accumulation through Modulation of Metabolic Genes in a Human Hepatocyte Model That Mimics Steatosis
inferred← citeshttps://doi.org/10.3390/jcm14124234openalex-snapshot
Involvement of miRNAs in the Cluster of Metabolic Factors of MetS: Nutrition-Genome-MetS Axis
inferred← citeshttps://doi.org/10.3390/membranes12040352openalex-snapshot
Plant-RNA in Extracellular Vesicles: The Secret of Cross-Kingdom Communication
inferred← citeshttps://doi.org/10.3390/molecules26092763openalex-snapshot
Onion (Allium cepa L.)-Derived Nanoparticles Inhibited LPS-Induced Nitrate Production, However, Their Intracellular Incorporation by Endocytosis Was Not Involved in This Effect on RAW264 Cells
inferred← citeshttps://doi.org/10.3390/ncrna11010006openalex-snapshot
In Silico Prediction of Maize microRNA as a Xanthine Oxidase Inhibitor: A New Approach to Treating Hyperuricemia Patients
inferred← citeshttps://doi.org/10.3390/nu16183146openalex-snapshot
Plant miR6262 Modulates the Expression of Metabolic and Thermogenic Genes in Human Hepatocytes and Adipocytes
inferred← citeshttps://doi.org/10.3724/abbs.2026010openalex-snapshot
Distinct miR319a identified from Persicaria chinensis mediates cross-kingdom suppression of cervical cancer by targeting ITGA3
inferred← citeshttps://doi.org/10.3945/jn.116.238949openalex-snapshot
Biological Activities of Extracellular Vesicles and Their Cargos from Bovine and Human Milk in Humans and Implications for Infants
inferred← citeshttps://doi.org/10.4081/jphia.2018.841openalex-snapshot
Investigation of medicinal plants traditionally used as dietary supplements: A review on Moringa oleifera
inferred← citeshttps://doi.org/10.48130/frures-2021-0005openalex-snapshot
microRNA regulation of fruit development, quality formation and stress response
inferred← citeshttps://doi.org/10.5114/ceji.2018.81351openalex-snapshot
Regulation of TLR signaling pathways by microRNAs: implications in inflammatory diseases
inferred← citeshttps://doi.org/10.55705/cmbr.2022.365396.1085openalex-snapshot
MicroRNAs; their therapeutic and biomarker properties
inferred← citeshttps://doi.org/10.58830/ozgur.pub392openalex-snapshot
Matematik ve Fen Bilimleri Üzerine Araştırmalar-IV
inferred← citeshttps://doi.org/10.58830/ozgur.pub392.c1548openalex-snapshot
What is Artificial Intelligence?
inferred← citeshttps://doi.org/10.58830/ozgur.pub392.c1549openalex-snapshot
Food Allergy: Molecular Basis and the Potential Novel Role of microRNAs
inferred← citeshttps://doi.org/10.58830/ozgur.pub392.c1550openalex-snapshot
Trifolium medium var. medium (Fabaceae) Taksonunun Vejetatif Organlarının Anatomik Özellikleri
inferred← citeshttps://doi.org/10.58830/ozgur.pub392.c1551openalex-snapshot
Abiyotik Stres Faktörleriyle Başa Çıkma: Humik Asitler (HA)
inferred← citeshttps://doi.org/10.58830/ozgur.pub392.c1552openalex-snapshot
Protein Adsorpsiyonu Üzerine Bir Derleme
inferred← citeshttps://doi.org/10.7150/thno.97096openalex-snapshot
Exosome-like nanoparticles derived from fruits, vegetables, and herbs: innovative strategies of therapeutic and drug delivery
inferred← citeshttps://doi.org/10.7717/peerj.5186openalex-snapshot
Identification of exosome-like nanoparticle-derived microRNAs from 11 edible fruits and vegetables
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