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Granny Smith apple procyanidin extract upregulates tight junction protein expression and modulates oxidative stress and inflammation in lipopolysaccharide-induced Caco-2 cells
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/biof.5520130119openalex-snapshot
Proanthocyanidins and human health: Systemic effects and local effects in the gut
inferredcites →https://doi.org/10.1016/j.ajpath.2012.10.014openalex-snapshot
Lipopolysaccharide Causes an Increase in Intestinal Tight Junction Permeability in Vitro and in Vivo by Inducing Enterocyte Membrane Expression and Localization of TLR-4 and CD14
inferredcites →https://doi.org/10.1016/j.coph.2009.06.022openalex-snapshot
The tight junction in inflammatory disease: communication breakdown
inferredcites →https://doi.org/10.1016/j.jaci.2009.05.038openalex-snapshot
Intestinal barrier function: Molecular regulation and disease pathogenesis
inferredcites →https://doi.org/10.1016/j.pharmthera.2011.02.004openalex-snapshot
Polyphenols as small molecular inhibitors of signaling cascades in carcinogenesis
inferredcites →https://doi.org/10.1021/jf020071copenalex-snapshot
Vitamin C Equivalent Antioxidant Capacity (VCEAC) of Phenolic Phytochemicals
inferredcites →https://doi.org/10.1021/jf072679xopenalex-snapshot
Rapid Preparation of Procyanidins B2 and C1 from Granny Smith Apples by Using Low Pressure Column Chromatography and Identification of Their Oligomeric Procyanidins
inferredcites →https://doi.org/10.1021/jf200553sopenalex-snapshot
Apple Peel Polyphenols Protect against Gastrointestinal Mucosa Alterations Induced by Indomethacin in Rats
inferredcites →https://doi.org/10.1021/jf981372iopenalex-snapshot
Evaluation of Radical Scavenging Activity of Fresh and Air-Dried Tomatoes by Three Model Reactions
inferredcites →https://doi.org/10.1038/35016151openalex-snapshot
Antioxidant activity of fresh apples
inferredcites →https://doi.org/10.1080/10408397809527250openalex-snapshot
Activated oxygen species and oxidation of food constituents
inferredcites →https://doi.org/10.1080/10408398.2016.1152230openalex-snapshot
Regulation of the intestinal tight junction by natural polyphenols: A mechanistic perspective
inferredcites →https://doi.org/10.1089/ars.2012.4530openalex-snapshot
Inflammatory Bowel Disease: Mechanisms, Redox Considerations, and Therapeutic Targets
inferredcites →https://doi.org/10.1093/ajcn/79.5.727openalex-snapshot
Polyphenols: food sources and bioavailability
inferredcites →https://doi.org/10.1093/jn/138.6.1067openalex-snapshot
Quercetin Enhances Epithelial Barrier Function and Increases Claudin-4 Expression in Caco-2 Cells3
inferredcites →https://doi.org/10.1096/fasebj.9.8.7768354openalex-snapshot
Caco‐2 cells as a model for intestinal lipoprotein synthesis and secretion
inferredcites →https://doi.org/10.1111/j.1753-4887.2009.00210.xopenalex-snapshot
Dietary polyphenols can modulate the intestinal inflammatory response
inferredcites →https://doi.org/10.1136/gut.2006.094599openalex-snapshot
Polyphenols in the treatment of inflammatory bowel disease and acute pancreatitis
inferredcites →https://doi.org/10.1177/0884533611400233openalex-snapshot
Diet in Inflammatory Bowel Disease
inferredcites →https://doi.org/10.1242/jcs.070896openalex-snapshot
TNFα-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFκB signaling
inferredcites →https://doi.org/10.1371/journal.pone.0061944openalex-snapshot
Amelioration of IFN-γ and TNF-α-Induced Intestinal Epithelial Barrier Dysfunction by Berberine via Suppression of MLCK-MLC Phosphorylation Signaling Pathway
inferredcites →https://doi.org/10.1371/journal.pone.0107606openalex-snapshot
Relationships between Degree of Polymerization and Antioxidant Activities: A Study on Proanthocyanidins from the Leaves of a Medicinal Mangrove Plant Ceriops tagal
inferredcites →https://doi.org/10.2527/jas.2008-1339openalex-snapshot
Stress-induced gastrointestinal barrier dysfunction and its inflammatory effects1
inferredcites →https://doi.org/10.3748/wjg.v22.i11.3117openalex-snapshot
Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer
inferredcites →https://doi.org/10.5073/jabfq.2009.083.017openalex-snapshot
Influence of apple polyphenols on the intestinal barrier in a colonic cell model
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4795439openalex-extracted
Microbiome Mediated Impact of Food Grade Carrageenan on the Barrier Function
inferred← citeshttps://doi.org/10.1002/cbdv.202201046openalex-snapshot
Involvement of the DAF‐16/FOXO Pathway in the Antioxidant Activity of the Jaboticaba (Myrciaria trunciflora) Extract against Various Stressors Using Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1002/efd2.150openalex-snapshot
Flavonoid profiling of Plumula nelumbinis and evaluation of their anti‐inflammatory effects on lipopolysaccharide‐induced RAW 264.7 macrophages
inferred← citeshttps://doi.org/10.1002/fsn3.2854openalex-snapshot
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Heat stress induced IPEC‐J2 cells barrier dysfunction through endoplasmic reticulum stress mediated apoptosis by p‐eif2α/CHOP pathway
inferred← citeshttps://doi.org/10.1002/jsfa.11945openalex-snapshot
Peanut skin procyanidins ameliorate insulin resistance via modulation of gut microbiota and gut barrier in type 2 diabetic mice
inferred← citeshttps://doi.org/10.1007/s00394-020-02222-3openalex-snapshot
Protective properties of grape-seed proanthocyanidins in human ex vivo acute colonic dysfunction induced by dextran sodium sulfate
inferred← citeshttps://doi.org/10.1007/s00726-021-03082-9openalex-snapshot
A mix of functional amino acids and grape polyphenols promotes the growth of piglets, modulates the gut microbiota in vivo and regulates epithelial homeostasis in intestinal organoids
inferred← citeshttps://doi.org/10.1007/s10620-020-06676-7openalex-snapshot
Phenolic Compounds Promote Diversity of Gut Microbiota and Maintain Colonic Health
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Highly Oriented Thermoplastic Poly (vinyl alcohol) Films by Uniaxial Drawing: Effect of Stretching Temperature and Draw Ratio
inferred← citeshttps://doi.org/10.1016/b978-0-323-85273-9.00005-3openalex-snapshot
Impact of polyphenols on human gut microbiome and associated biomarkers
inferred← citeshttps://doi.org/10.1016/j.anifeedsci.2021.115118openalex-snapshot
Effects of high-concentrate diet supplemented with grape seed procyanidins on the colonic fermentation, colonic morphology, and inflammatory response in lambs
inferred← citeshttps://doi.org/10.1016/j.biopha.2022.112831openalex-snapshot
The Regulatory effect of chlorogenic acid on gut-brain function and its mechanism: A systematic review
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115076openalex-snapshot
Procyanidin improves experimental colitis by regulating macrophage polarization
inferred← citeshttps://doi.org/10.1016/j.carbpol.2023.121722openalex-snapshot
Fucosylated chondroitin sulfate from sea cucumber Stichopus chloronotus alleviate the intestinal barrier injury and oxidative stress damage in vitro and in vivo
inferred← citeshttps://doi.org/10.1016/j.fbio.2025.105831openalex-snapshot
Microbiome mediated impact of food grade carrageenan on the intestinal barrier function
inferred← citeshttps://doi.org/10.1016/j.fochx.2023.100697openalex-snapshot
The synergistic ramification of insoluble dietary fiber and associated non-extractable polyphenols on gut microbial population escorting alleviation of lifestyle diseases
inferred← citeshttps://doi.org/10.1016/j.foodchem.2024.141049openalex-snapshot
Apple polyphenols prevent patulin-induced intestinal damage by modulating the gut microbiota and metabolism of the gut-liver axis
inferred← citeshttps://doi.org/10.1016/j.foodres.2020.109240openalex-snapshot
Transport, metabolism and remedial potential of functional food extracts (FFEs) in Caco-2 cells monolayer: A review
inferred← citeshttps://doi.org/10.1016/j.foodres.2023.112634openalex-snapshot
Bioaccessibility and transport of lentil hull polyphenols in vitro, and their bioavailability and metabolism in rats
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2021.01.164openalex-snapshot
Qingke β-glucan synergizes with a β-glucan-utilizing Lactobacillus strain to relieve capsaicin-induced gastrointestinal injury in mice
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.137811openalex-snapshot
Fucoidan from Stichopus chloronotus relieved DSS induced ulcerative colitis through inhibiting intestinal barrier disruption and oxidative stress
inferred← citeshttps://doi.org/10.1016/j.jff.2019.103663openalex-snapshot
Protective effects of grape seed procyanidin extract on intestinal barrier dysfunction induced by a long-term high-fat diet
inferred← citeshttps://doi.org/10.1016/j.jff.2021.104822openalex-snapshot
Egg white ovomucin hydrolysate inhibits intestinal integrity damage in LPS-treated Caco-2 cells
inferred← citeshttps://doi.org/10.1016/j.jff.2022.105139openalex-snapshot
Lactobacillus casei-fermented blueberry pomace ameliorates colonic barrier function in high fat diet mice through MAPK-NF-κB-MLCK signaling pathway
inferred← citeshttps://doi.org/10.1016/j.jff.2026.107275openalex-snapshot
EGCG ameliorates ulcerative colitis in mice via inhibition of the Notch signaling pathway
inferred← citeshttps://doi.org/10.1016/j.lwt.2024.116992openalex-snapshot
Evaluation of the antioxidant activity and prebiotic properties of mangosteen peel proanthocyanidin extracts through simulated in vitro digestion and colonic fermentation
inferred← citeshttps://doi.org/10.1016/j.phrs.2019.104461openalex-snapshot
Enhancement of epithelial cell autophagy induced by sinensetin alleviates epithelial barrier dysfunction in colitis
inferred← citeshttps://doi.org/10.1016/j.phrs.2020.105135openalex-snapshot
Targeting gut barrier dysfunction with phytotherapies: Effective strategy against chronic diseases
inferred← citeshttps://doi.org/10.1016/j.phrs.2025.108082openalex-snapshot
Advance in neuroprotective effects of proanthocyanidins (PCs): Structure, absorption, bioactivities, mechanism, and perspectives
inferred← citeshttps://doi.org/10.1016/j.postharvbio.2019.110999openalex-snapshot
Exogenous procyanidin treatment delays senescence of harvested banana fruit by enhancing antioxidant responses and in vivo procyanidin content
inferred← citeshttps://doi.org/10.1016/j.tifs.2020.10.033openalex-snapshot
Recent advances on dietary polyphenol's potential roles in Celiac Disease
inferred← citeshttps://doi.org/10.1021/acs.jafc.1c07761openalex-snapshot
DHA-Enriched Phospholipids and EPA-Enriched Phospholipids Alleviate Lipopolysaccharide-Induced Intestinal Barrier Injury in Mice via a Sirtuin 1-Dependent Mechanism
inferred← citeshttps://doi.org/10.1021/acs.jafc.2c04101openalex-snapshot
Differential Protective Effect of Resveratrol and Its Microbial Metabolites on Intestinal Barrier Dysfunction is Mediated by the AMPK Pathway
inferred← citeshttps://doi.org/10.1021/acs.jafc.3c00798openalex-snapshot
Heat Stress-Induced Intestinal Barrier Impairment: Current Insights into the Aspects of Oxidative Stress and Endoplasmic Reticulum Stress
inferred← citeshttps://doi.org/10.1021/acs.jafc.4c03544openalex-snapshot
Proanthocyanidins and β-Glucan Synergistically Regulate Intestinal Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice
inferred← citeshttps://doi.org/10.1038/s41538-024-00283-wopenalex-snapshot
Sugar-sweetened beverage but not diluted cloudy apple juice consumption induces post-prandial endotoxemia in healthy adults
inferred← citeshttps://doi.org/10.1038/s41598-026-39008-2openalex-snapshot
Cranberry extract-supplemented microbiota effluents enhance intestinal barrier integrity via mucin production and antimicrobial activity in murine organoids
inferred← citeshttps://doi.org/10.1039/c8nj06160bopenalex-snapshot
Green synthesis of silver nanoparticles using one-pot and microwave-assisted methods and their subsequent embedment on PVDF nanofibre membranes for growth inhibition of mesophilic and thermophilic bacteria
inferred← citeshttps://doi.org/10.1039/c9fo00123aopenalex-snapshot
Dietary l -tryptophan alleviated LPS-induced intestinal barrier injury by regulating tight junctions in a Caco-2 cell monolayer model
inferred← citeshttps://doi.org/10.1039/c9fo02517kopenalex-snapshot
Fermented blueberry pomace ameliorates intestinal barrier function through the NF-κB-MLCK signaling pathway in high-fat diet mice
inferred← citeshttps://doi.org/10.1039/d1fo01918jopenalex-snapshot
Procyanidin A 1 and its digestive products prevent acrylamide-induced intestinal barrier dysfunction via the MAPK-mediated MLCK pathway
inferred← citeshttps://doi.org/10.1039/d3fo02731gopenalex-snapshot
Maillard-type glycated collagen with alginate oligosaccharide suppresses inflammation and oxidative stress by attenuating the expression of LPS receptors Tlr4 and Cd14 in macrophages
inferred← citeshttps://doi.org/10.1039/d3fo05579eopenalex-snapshot
Bound polyphenols in insoluble dietary fiber of navel orange peel modulate LPS-induced intestinal-like co-culture inflammation through CSF2-mediated NF-κB/JAK-STAT pathway
inferred← citeshttps://doi.org/10.1039/d4fo03950eopenalex-snapshot
The influence of fruit juice extracts on glucose intestinal transporters and antioxidant genes in a Caco-2 and HT29-MTX co-culture cell system
inferred← citeshttps://doi.org/10.1039/d4fo04721dopenalex-snapshot
A review on the effects of flavan-3-ols, their metabolites, and their dietary sources on gut barrier integrity
inferred← citeshttps://doi.org/10.1039/d5fo03351aopenalex-snapshot
The effects of phenolic acid supplementation on intestinal barrier function: a review
inferred← citeshttps://doi.org/10.1079/9781800621671.0005openalex-snapshot
An Evidence-Based Review of Medicinal Plants Cited inCanon of Medicinefor Management of Inflammatory Bowel Disease
inferred← citeshttps://doi.org/10.1080/10408398.2019.1570913openalex-snapshot
Phytochemicals and inflammatory bowel disease: a review
inferred← citeshttps://doi.org/10.1080/10408398.2022.2030296openalex-snapshot
Dietary proanthocyanidins on gastrointestinal health and the interactions with gut microbiota
inferred← citeshttps://doi.org/10.1080/10408398.2022.2105802openalex-snapshot
Proanthocyanidins at the gastrointestinal tract: mechanisms involved in their capacity to mitigate obesity-associated metabolic disorders
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The therapeutic effect of phytochemicals on aflatoxin B1-induced intestinal injury: the roles of oxidative stress and inflammation
inferred← citeshttps://doi.org/10.1093/jn/nxz088openalex-snapshot
Lactobacillus reuteri ZJ617 Culture Supernatant Attenuates Acute Liver Injury Induced in Mice by Lipopolysaccharide
inferred← citeshttps://doi.org/10.1093/jpp/rgaa044openalex-snapshot
Glochidion ellipticum Wight extracts ameliorate dextran sulfate sodium-induced colitis in mice by modulating nuclear factor kappa-light-chain-enhancer of activated B cells signalling pathway
inferred← citeshttps://doi.org/10.1096/fj.202400287ropenalex-snapshot
Night‐restricted feeding improves colonic barrier function and reduces inflammation by optimizing gut microbial composition in growing pigs during the hot season
inferred← citeshttps://doi.org/10.1371/journal.pone.0283607openalex-snapshot
Grape seed meal by-product is able to counteract oxidative stress induced by lipopolysaccharide and dextran sulphate in IPEC cells and piglets after weaning
inferred← citeshttps://doi.org/10.22541/au.171017897.77896795/v1openalex-snapshot
Colitis can be Improved by (−)-Epigallocatechin Gallate through Targeting Notch in DSS-induced UC mice
inferred← citeshttps://doi.org/10.31838/srp.2020.4.84openalex-snapshot
Antioxidant and Antitumor Activities of Methanolic Extracts Obtained from Red Delicious and Granny Smith Apples' Seeds
inferred← citeshttps://doi.org/10.3389/fmicb.2019.00522openalex-snapshot
Musca domestica Cecropin (Mdc) Alleviates Salmonella typhimurium-Induced Colonic Mucosal Barrier Impairment: Associating With Inflammatory and Oxidative Stress Response, Tight Junction as Well as Intestinal Flora
inferred← citeshttps://doi.org/10.3389/fmicb.2023.1137701openalex-snapshot
Alleviation of DSS-induced colitis in mice by a new-isolated Lactobacillus acidophilus C4
inferred← citeshttps://doi.org/10.3389/fmicb.2024.1347053openalex-snapshot
Effects of dietary chlorogenic acid on cecal microbiota and metabolites in broilers during lipopolysaccharide-induced immune stress
inferred← citeshttps://doi.org/10.3389/fnut.2022.1098954openalex-snapshot
Red-fleshed apple flavonoid extract alleviates CCl4-induced liver injury in mice
inferred← citeshttps://doi.org/10.3389/fvets.2025.1513371openalex-snapshot
Condensed tannin from Caragana korshinskii extraction and protection effects on intestinal barrier function in mice
inferred← citeshttps://doi.org/10.3390/antibiotics11010110openalex-snapshot
Protective Effects of Grape Seed Oligomeric Proanthocyanidins in IPEC-J2–Escherichia coli/Salmonella Typhimurium Co-Culture
inferred← citeshttps://doi.org/10.3390/antibiotics12111615openalex-snapshot
Protective Effect of Procyanidin-Rich Grape Seed Extract against Gram-Negative Virulence Factors
inferred← citeshttps://doi.org/10.3390/antiox10081229openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/antiox14070850openalex-snapshot
Therapeutic Potential of Proanthocyanidins in Dentistry: A Focus on Periodontal Disease and on Dental Implants in Osteoporotic Patients
inferred← citeshttps://doi.org/10.3390/antiox8080250openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/antiox9121267openalex-snapshot
Antioxidant Activity of Flavonoids in LPS-Treated IPEC-J2 Porcine Intestinal Epithelial Cells and Their Antibacterial Effect against Bacteria of Swine Origin
inferred← citeshttps://doi.org/10.3390/books978-3-0365-4459-5openalex-snapshot
Food Processing and Its Impact on Phenolic and other Bioactive Constituents in Food
inferred← citeshttps://doi.org/10.3390/foods10020279openalex-snapshot
Innovative Technologies for Extraction and Microencapsulation of Bioactives from Plant-Based Food Waste and Their Applications in Functional Food Development
inferred← citeshttps://doi.org/10.3390/foods11213535openalex-snapshot
Different Structures of Arabinoxylan Hydrolysates Alleviated Caco-2 Cell Barrier Damage by Regulating the TLRs/MyD88/NF-κB Pathway
inferred← citeshttps://doi.org/10.3390/foods15081293openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/foods8100471openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/ijms231911162openalex-snapshot
Lactobacillus rhamnosus CY12 Enhances Intestinal Barrier Function by Regulating Tight Junction Protein Expression, Oxidative Stress, and Inflammation Response in Lipopolysaccharide-Induced Caco-2 Cells
inferred← citeshttps://doi.org/10.3390/molecules25225263openalex-snapshot
The Qualitative and Quantitative Compositions of Phenolic Compounds in Fruits of Lithuanian Heirloom Apple Cultivars
inferred← citeshttps://doi.org/10.3390/nu11050979openalex-snapshot
Grape-Seed Proanthocyanidins are Able to Reverse Intestinal Dysfunction and Metabolic Endotoxemia Induced by a Cafeteria Diet in Wistar Rats
inferred← citeshttps://doi.org/10.3390/nu12010130openalex-snapshot
Health-Promoting Properties of Proanthocyanidins for Intestinal Dysfunction
inferred← citeshttps://doi.org/10.3390/nu14132679openalex-snapshot
Non-Celiac Gluten Sensitivity and Protective Role of Dietary Polyphenols
inferred← citeshttps://doi.org/10.5772/intechopen.91212openalex-snapshot
Beneficial Effects of Proanthocyanidins on Intestinal Permeability and Its Relationship with Inflammation
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