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Architectural transitions in Vibrio cholerae biofilms at single-cell resolution

https://doi.org/10.1073/pnas.1601702113
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Liquid transport facilitated by channels in Bacillus subtilis biofilms
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Mechanically-driven phase separation in a growing bacterial colony
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In situ proteolysis of the Vibrio cholerae matrix protein RbmA promotes biofilm recruitment
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Focus on the physics of biofilms
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THE EFFECTS OF SHAPE ON THE INTERACTION OF COLLOIDAL PARTICLES
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inferredcites →https://doi.org/10.1126/science.1181185openalex-snapshot
Vibrio cholerae VpsT Regulates Matrix Production and Motility by Directly Sensing Cyclic di-GMP
inferredcites →https://doi.org/10.1126/science.1211037openalex-snapshot
Active Starvation Responses Mediate Antibiotic Tolerance in Biofilms and Nutrient-Limited Bacteria
inferredcites →https://doi.org/10.1126/science.1222981openalex-snapshot
Molecular Architecture and Assembly Principles of Vibrio cholerae Biofilms
inferredcites →https://doi.org/10.1128/cmr.15.2.167-193.2002openalex-snapshot
Biofilms: Survival Mechanisms of Clinically Relevant Microorganisms
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Structural Basis for Biofilm Formation via the Vibrio cholerae Matrix Protein RbmA
inferredcites →https://doi.org/10.1128/jb.00946-13openalex-snapshot
Cellulose as an Architectural Element in Spatially Structured Escherichia coli Biofilms
inferredcites →https://doi.org/10.1128/jb.01569-06openalex-snapshot
The rbmBCDEF Gene Cluster Modulates Development of Rugose Colony Morphology and Biofilm Formation in Vibrio cholerae
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Identification and Characterization of RbmA, a Novel Protein Required for the Development of Rugose Colony Morphology and Biofilm Structure in Vibrio cholerae
inferredcites →https://doi.org/10.1128/mbio.00103-13openalex-snapshot
Microanatomy at Cellular Resolution and Spatial Order of Physiological Differentiation in a Bacterial Biofilm
inferredcites →https://doi.org/10.1128/mbio.02456-14openalex-snapshot
A Hierarchical Cascade of Second Messengers Regulates Pseudomonas aeruginosa Surface Behaviors
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Microfluidics Expanding the Frontiers of Microbial Ecology
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inferredcites →https://doi.org/10.1371/journal.pone.0082458openalex-snapshot
Structural Insights into RbmA, a Biofilm Scaffolding Protein of V. Cholerae
inferredcites →https://doi.org/10.1371/journal.ppat.1002210openalex-snapshot
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What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Ultra-lightweight living structural material for enhanced stiffness and environmental sensing
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Non-invasive single-cell morphometry in living bacterial biofilms
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Social motility of biofilm-like microcolonies in a gliding bacterium
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Mechanical forces drive a reorientation cascade leading to biofilm self-patterning
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Quorum-sensing control of matrix protein production drives fractal wrinkling and interfacial localization of Vibrio cholerae pellicles
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Emergent collective alignment gives competitive advantage to longer cells during range expansion
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Nonlinear rheological characteristics of single species bacterial biofilms
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Streptococcus mutans adhesion force sensing in multi-species oral biofilms
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Dynamic biofilm architecture confers individual and collective mechanisms of viral protection
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Quantitative image analysis of microbial communities with BiofilmQ
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Verticalization of bacterial biofilms
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Emergence of three-dimensional order and structure in growing biofilms
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A living liquid crystal dissected
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Bacteria solve the problem of crowding by moving slowly
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Biofilms as self-shaping growing nematics
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Pili mediated intercellular forces shape heterogeneous bacterial microcolonies prior to multicellular differentiation
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Characterization of the biofilm matrix composition of psychrotrophic, meat spoilage pseudomonads
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Shear stress affects the architecture and cohesion of Chlorella vulgaris biofilms
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Instantaneous Clearing of Biofilm (iCBiofilm): an optical approach to revisit bacterial and fungal biofilm imaging
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Collective mechano-response dynamically tunes cell-size distributions in growing bacterial colonies
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Proliferating active matter
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Mechanobiology of bacterial biofilms: from structure and rheology to developmental dynamics and environmental adaptation
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Modulation of the mechanical properties of bacterial biofilms in response to environmental challenges
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Matrix composition determines the dimensions of Bacillus subtilis NCIB 3610 biofilm colonies grown on LB agar
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Importance of the biofilm matrix for the erosion stability of Bacillus subtilis NCIB 3610 biofilms
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When does entropy promote local organization?
inferred← citeshttps://doi.org/10.1039/d2sm01365gopenalex-snapshot
A mechanistic understanding of microcolony morphogenesis: coexistence of mobile and sessile aggregates
inferred← citeshttps://doi.org/10.1039/d3sm00880kopenalex-snapshot
Instabilities in a growing system of active particles: scalar and vectorial systems
inferred← citeshttps://doi.org/10.1039/d4sm01180eopenalex-snapshot
Morphogenesis of confined biofilms: how mechanical interactions determine cellular patterning and global geometry
inferred← citeshttps://doi.org/10.1063/5.0080845openalex-snapshot
Varied solutions to multicellularity: The biophysical and evolutionary consequences of diverse intercellular bonds
inferred← citeshttps://doi.org/10.1063/5.0216862openalex-snapshot
Machine learning assisted sorting of active microswimmers
inferred← citeshttps://doi.org/10.1071/ma22010openalex-snapshot
Feedback loops between mathematics and microbiology
inferred← citeshttps://doi.org/10.1071/mav43n1openalex-snapshot
Volume 43 Number 1
inferred← citeshttps://doi.org/10.1073/pnas.1603016113openalex-snapshot
Three-dimensional architecture of Vibrio cholera biofilms
inferred← citeshttps://doi.org/10.1073/pnas.1611494113openalex-snapshot
Vibrio cholerae biofilm growth program and architecture revealed by single-cell live imaging
inferred← citeshttps://doi.org/10.1073/pnas.1708954115openalex-snapshot
A growing microcolony can survive and support persistent propagation of virulent phages
inferred← citeshttps://doi.org/10.1073/pnas.1718813115openalex-snapshot
Dynamic switching enables efficient bacterial colonization in flow
inferred← citeshttps://doi.org/10.1073/pnas.1719317115openalex-snapshot
Spatial determinants of quorum signaling in a Pseudomonas aeruginosa infection model
inferred← citeshttps://doi.org/10.1073/pnas.1808469115openalex-snapshot
Exopolysaccharide protects Vibrio cholerae from exogenous attacks by the type 6 secretion system
inferred← citeshttps://doi.org/10.1073/pnas.1811722116openalex-snapshot
Learning the space-time phase diagram of bacterial swarm expansion
inferred← citeshttps://doi.org/10.1073/pnas.1819016116openalex-snapshot
Vibrio cholerae filamentation promotes chitin surface attachment at the expense of competition in biofilms
inferred← citeshttps://doi.org/10.1073/pnas.1909447117openalex-snapshot
Biophysical principles of choanoflagellate self-organization
inferred← citeshttps://doi.org/10.1073/pnas.2010199117openalex-snapshot
Vibrio cholerae adapts to sessile and motile lifestyles by cyclic di-GMP regulation of cell shape
inferred← citeshttps://doi.org/10.1073/pnas.2023504118openalex-snapshot
Hierarchical transitions and fractal wrinkling drive bacterial pellicle morphogenesis
inferred← citeshttps://doi.org/10.1073/pnas.2109940118openalex-snapshot
Architecture of cell–cell junctions in situ reveals a mechanism for bacterial biofilm inhibition
inferred← citeshttps://doi.org/10.1073/pnas.2123469119openalex-snapshot
Social evolution of shared biofilm matrix components
inferred← citeshttps://doi.org/10.1073/pnas.2200930119openalex-snapshot
Biotropic liquid crystal phase transformations in cellulose-producing bacterial communities
inferred← citeshttps://doi.org/10.1073/pnas.2212650120openalex-snapshot
Breakdown of clonal cooperative architecture in multispecies biofilms and the spatial ecology of predation
inferred← citeshttps://doi.org/10.1073/pnas.2514210122openalex-snapshot
Single-cell lysis patterns morphogenesis of eDNA in the matrix of Pseudomonas aeruginosa biofilms
inferred← citeshttps://doi.org/10.1074/jbc.ra119.008335openalex-snapshot
The 1.9 Å crystal structure of the extracellular matrix protein Bap1 from Vibrio cholerae provides insights into bacterial biofilm adhesion
inferred← citeshttps://doi.org/10.1080/08927014.2017.1360870openalex-snapshot
Structural changes in S. epidermidis biofilms after transmission between stainless steel surfaces
inferred← citeshttps://doi.org/10.1080/08927014.2019.1669021openalex-snapshot
In situ characterisation of biofilms formed by psychrotrophic meat spoilage pseudomonads
inferred← citeshttps://doi.org/10.1088/1361-6633/aae546openalex-snapshot
Bacterial growth: a statistical physicist’s guide
inferred← citeshttps://doi.org/10.1088/1361-6633/ad058fopenalex-snapshot
Heterogeneous anomalous transport in cellular and molecular biology
inferred← citeshttps://doi.org/10.1088/1367-2630/aa983fopenalex-snapshot
Shape of the growing front of biofilms
inferred← citeshttps://doi.org/10.1088/1478-3975/aac473openalex-snapshot
Complex microbial systems across different levels of description
inferred← citeshttps://doi.org/10.1088/1478-3975/abdc0eopenalex-snapshot
Roadmap on emerging concepts in the physical biology of bacterial biofilms: from surface sensing to community formation
inferred← citeshttps://doi.org/10.1089/mdr.2017.0073openalex-snapshot
Nosocomial, Multidrug-Resistant Klebsiella pneumoniae Strains Isolated from Mexico City Produce Robust Biofilms on Abiotic Surfaces but Not on Human Lung Cells
inferred← citeshttps://doi.org/10.1093/femsre/fuaa062openalex-snapshot
Advances and opportunities in image analysis of bacterial cells and communities
inferred← citeshttps://doi.org/10.1093/femsre/fuaf067openalex-snapshot
Spatial structure: shaping the ecology and evolution of microbial communities
inferred← citeshttps://doi.org/10.1093/femsre/fuy001openalex-snapshot
Emergent heterogeneous microenvironments in biofilms: substratum surface heterogeneity and bacterial adhesion force-sensing
inferred← citeshttps://doi.org/10.1098/rsfs.2022.0062openalex-snapshot
Formation and emergent dynamics of spatially organized microbial systems
inferred← citeshttps://doi.org/10.1098/rsif.2020.0486openalex-snapshot
Accumulation of dead cells from contact killing facilitates coexistence in bacterial biofilms
inferred← citeshttps://doi.org/10.1098/rsos.170463openalex-snapshot
Role of growth rate on the orientational alignment ofEscherichia coliin a slit
inferred← citeshttps://doi.org/10.1101/086462openalex-snapshot
Phage mobility is a core determinant of phage-bacteria coexistence in biofilms
inferred← citeshttps://doi.org/10.1101/2021.05.11.440221openalex-snapshot
Biofilm self-patterning: mechanical forces drive a reorientation cascade
inferred← citeshttps://doi.org/10.1101/2021.08.06.455416openalex-snapshot
Multispecies phase diagram of biofilm architectures reveals biophysical principles of biofilm development
inferred← citeshttps://doi.org/10.1101/2023.06.20.545666openalex-snapshot
Cell arrangement impacts metabolic activity and antibiotic tolerance in Pseudomonas aeruginosa biofilms
inferred← citeshttps://doi.org/10.1101/2024.07.17.603784openalex-snapshot
Cell-scale gene-expression measurements in Vibrio cholerae biofilms reveal spatiotemporal patterns underlying development
inferred← citeshttps://doi.org/10.1101/2024.10.13.618088openalex-snapshot
Surfactin accelerates Bacillus subtilis pellicle biofilm development
inferred← citeshttps://doi.org/10.1101/2024.10.13.618105openalex-snapshot
Real-time high-resolution microscopy reveals how single-cell lysis shapes biofilm matrix morphogenesis
inferred← citeshttps://doi.org/10.1101/2025.01.12.632655openalex-snapshot
Kinking and buckling instability in growing bacterial chains
inferred← citeshttps://doi.org/10.1101/2025.06.03.657734openalex-snapshot
Single-cell imaging reveals spontaneous phenotypic sorting and bet-hedging in developing biofilms
inferred← citeshttps://doi.org/10.1101/2025.07.28.667140openalex-snapshot
Targeted disruption of phage liquid crystalline droplets abolishes antibiotic tolerance of bacterial biofilms
inferred← citeshttps://doi.org/10.1101/2025.09.29.679375openalex-snapshot
Prophage induction states drive structural and synergistic outcomes in marine bacterial biofilms
inferred← citeshttps://doi.org/10.1101/627208openalex-snapshot
Flow-induced symmetry breaking in growing bacterial biofilms
inferred← citeshttps://doi.org/10.1101/851428openalex-snapshot
Functional channels in mature E. coli colonies
inferred← citeshttps://doi.org/10.1103/2zm9-r3qsopenalex-snapshot
Computational model of fractal interface formation in bacterial biofilms
inferred← citeshttps://doi.org/10.1103/8wdc-fl92openalex-snapshot
Biofilms as living soft materials: Towards a mechanistic description of their linear and nonlinear mechanics
inferred← citeshttps://doi.org/10.1103/g5bm-m9c4openalex-snapshot
Structured interactions drive abrupt transitions in the spatial organization of microbial communities
inferred← citeshttps://doi.org/10.1103/physreve.102.032408openalex-snapshot
Diffusion of antibiotics through a biofilm in the presence of diffusion and absorption barriers
inferred← citeshttps://doi.org/10.1103/physrevlett.123.258101openalex-snapshot
Flow-Induced Symmetry Breaking in Growing Bacterial Biofilms
inferred← citeshttps://doi.org/10.1103/physrevresearch.2.043334openalex-snapshot
Analogies between growing dense active matter and soft driven glasses
inferred← citeshttps://doi.org/10.1109/icip.2018.8451137openalex-snapshot
Bacterial Image Analysis and Single-Cell Analytics to Decipher the Behavior of Large Microbial Communities
inferred← citeshttps://doi.org/10.1111/1541-4337.13283openalex-snapshot
Sources and contamination routes of seafood with human pathogenic Vibrio spp.: A Farm‐to‐Fork approach
inferred← citeshttps://doi.org/10.1111/2041-210x.70022openalex-snapshot
Bacterial colony biopsies: Spatial discrimination of heterogeneous cell types by cytometric fingerprinting
inferred← citeshttps://doi.org/10.1111/mmi.15064openalex-snapshot
Single‐cell segmentation in bacterial biofilms with an optimized deep learning method enables tracking of cell lineages and measurements of growth rates
inferred← citeshttps://doi.org/10.1126/science.abb8501openalex-snapshot
Cell position fates and collective fountain flow in bacterial biofilms revealed by light-sheet microscopy
inferred← citeshttps://doi.org/10.1126/science.abd1225openalex-snapshot
Tracing cell trajectories in a biofilm
inferred← citeshttps://doi.org/10.1126/science.adf3345openalex-snapshot
Alcanivorax borkumensis biofilms enhance oil degradation by interfacial tubulation
inferred← citeshttps://doi.org/10.1128/aem.02343-17openalex-snapshot
Influence of Type I Fimbriae and Fluid Shear Stress on Bacterial Behavior and Multicellular Architecture of Early Escherichia coli Biofilms at Single-Cell Resolution
inferred← citeshttps://doi.org/10.1128/jb.00101-19openalex-snapshot
Regulating, Measuring, and Modeling the Viscoelasticity of Bacterial Biofilms
inferred← citeshttps://doi.org/10.1128/mbio.00448-26openalex-snapshot
Label-free microscopy enables high-throughput identification of genes controlling biofilm development
inferred← citeshttps://doi.org/10.1128/mbio.01096-26openalex-snapshot
Ordered assembly of the Vibrio cholerae biofilm exopolysaccharide defined by lipid-linked intermediate profiling
inferred← citeshttps://doi.org/10.1128/mbio.01375-19openalex-snapshot
Chitosan Films for Microfluidic Studies of Single Bacteria and Perspectives for Antibiotic Susceptibility Testing
inferred← citeshttps://doi.org/10.1128/mbio.01885-22openalex-snapshot
VxrB Influences Antagonism within Biofilms by Controlling Competition through Extracellular Matrix Production and Type 6 Secretion
inferred← citeshttps://doi.org/10.1128/mbio.03534-20openalex-snapshot
Understanding the Basis of METH Mouth Using a Rodent Model of Methamphetamine Injection, Sugar Consumption, and Streptococcus mutans Infection
inferred← citeshttps://doi.org/10.1128/mbio.03935-24openalex-snapshot
Non-disruptive matrix turnover is a conserved feature of biofilm aggregate growth in paradigm pathogenic species
inferred← citeshttps://doi.org/10.1128/mmbr.00138-24openalex-snapshot
Resolving spatiotemporal dynamics in bacterial multicellular populations: approaches and challenges
inferred← citeshttps://doi.org/10.1137/17m1138625openalex-snapshot
Upscaling Diffusion Through First-Order Volumetric Sinks: A Homogenization of Bacterial Nutrient Uptake
inferred← citeshttps://doi.org/10.1140/epjst/e2018-800088-6openalex-snapshot
Life in crowded conditions
inferred← citeshttps://doi.org/10.1142/s0219519419500702openalex-snapshot
STUDYING THE INTERNAL STRESS HETEROGENEITY OF THE GROWING BIOFILM BY THE MICROPILLAR DEFORMATION OF THE GROWING SUBSTRATE
inferred← citeshttps://doi.org/10.1146/annurev-biophys-062920-063646openalex-snapshot
How Physical Interactions Shape Bacterial Biofilms
inferred← citeshttps://doi.org/10.1146/annurev-cellbio-100818-125119openalex-snapshot
Not Just Going with the Flow: The Effects of Fluid Flow on Bacteria and Plankton
inferred← citeshttps://doi.org/10.1146/annurev-micro-020518-115919openalex-snapshot
Bent Bacteria: A Comparison of Cell Shape Mechanisms in Proteobacteria
inferred← citeshttps://doi.org/10.1146/annurev-micro-111021-053553openalex-snapshot
Mechanisms Underlying Vibrio cholerae Biofilm Formation and Dispersion
inferred← citeshttps://doi.org/10.1186/s12859-021-04409-9openalex-snapshot
Analytics and visualization tools to characterize single-cell stochasticity using bacterial single-cell movie cytometry data
inferred← citeshttps://doi.org/10.1186/s12918-017-0399-zopenalex-snapshot
Image analysis driven single-cell analytics for systems microbiology
inferred← citeshttps://doi.org/10.1371/journal.pbio.3000429openalex-snapshot
The intragenus and interspecies quorum-sensing autoinducers exert distinct control over Vibrio cholerae biofilm formation and dispersal
inferred← citeshttps://doi.org/10.1371/journal.pbio.3001846openalex-snapshot
Shared biophysical mechanisms determine early biofilm architecture development across different bacterial species
inferred← citeshttps://doi.org/10.1371/journal.pbio.3001913openalex-snapshot
Multispecies biofilm architecture determines bacterial exposure to phages
inferred← citeshttps://doi.org/10.1371/journal.pbio.3002205openalex-snapshot
Cellular arrangement impacts metabolic activity and antibiotic tolerance in Pseudomonas aeruginosa biofilms
inferred← citeshttps://doi.org/10.1371/journal.pbio.3003187openalex-snapshot
Analysis of gene expression within individual cells reveals spatiotemporal patterns underlying Vibrio cholerae biofilm development
inferred← citeshttps://doi.org/10.1371/journal.pbio.3003834openalex-snapshot
Disrupting phage liquid crystalline droplets restores antibiotic susceptibility in Pseudomonas aeruginosa biofilms
inferred← citeshttps://doi.org/10.1371/journal.pcbi.1006094openalex-snapshot
Cell adhesion and fluid flow jointly initiate genotype spatial distribution in biofilms
inferred← citeshttps://doi.org/10.1371/journal.pone.0243280openalex-snapshot
Mechanics of biofilms formed of bacteria with fimbriae appendages
inferred← citeshttps://doi.org/10.1371/journal.ppat.1008745openalex-snapshot
A tyrosine phosphoregulatory system controls exopolysaccharide biosynthesis and biofilm formation in Vibrio cholerae
inferred← citeshttps://doi.org/10.1371/journal.ppat.1011193openalex-snapshot
Architecture and matrix assembly determinants of Bordetella pertussis biofilms on primary human airway epithelium
inferred← citeshttps://doi.org/10.17586/2687-0568-2021-3-1-1-28openalex-snapshot
Chemical Systems for Life Science
inferred← citeshttps://doi.org/10.3389/fcimb.2020.582947openalex-snapshot
Diguanylate Cyclases in Vibrio cholerae: Essential Regulators of Lifestyle Switching
inferred← citeshttps://doi.org/10.3389/fmicb.2017.01364openalex-snapshot
Spatial Organization Plasticity as an Adaptive Driver of Surface Microbial Communities
inferred← citeshttps://doi.org/10.3389/fmicb.2017.02534openalex-snapshot
Geometrical Distribution of Cryptococcus neoformans Mediates Flower-Like Biofilm Development
inferred← citeshttps://doi.org/10.3389/fmicb.2021.686793openalex-snapshot
Searching for the Secret of Stickiness: How Biofilms Adhere to Surfaces
inferred← citeshttps://doi.org/10.3389/fmicb.2022.915095openalex-snapshot
Lineage dynamics in growing biofilms: Spatial patterns of standing vs. de novo diversity
inferred← citeshttps://doi.org/10.3389/fmicb.2023.1211761openalex-snapshot
Dispersive biofilm from membrane bioreactor strains: effects of diffusible signal factor addition and characterization by dispersion index
inferred← citeshttps://doi.org/10.3390/antiox15030361openalex-snapshot
Measuring Communication in Microbial Biofilms in Response to Antibiotics, Phytochemicals and Stressors
inferred← citeshttps://doi.org/10.3390/medicina57080839openalex-snapshot
Mechanisms and Impact of Biofilms and Targeting of Biofilms Using Bioactive Compounds—A Review
inferred← citeshttps://doi.org/10.3390/microorganisms9020417openalex-snapshot
Agent Based Models of Polymicrobial Biofilms and the Microbiome—A Review
inferred← citeshttps://doi.org/10.48550/arxiv.2104.08380openalex-snapshot
Biofilm self-patterning: mechanical forces drive a reorientation cascade
inferred← citeshttps://doi.org/10.5488/cmp.27.13802openalex-snapshot
Toward a realistic model of multilayered bacterial colonies
inferred← citeshttps://doi.org/10.6084/m9.figshare.16907599openalex-snapshot
Additional file 1 of Analytics and visualization tools to characterize single-cell stochasticity using bacterial single-cell movie cytometry data
inferred← citeshttps://doi.org/10.64898/2026.08.30.748126openalex-snapshot
Genome-scale label-free imaging reveals cellular physiology encoded in bacterial collective architecture
inferred← citeshttps://doi.org/10.64898/2026.09.25.752283openalex-snapshot
Matrix-controlled emergence of biofilm architecture shapes antimicrobial survival
inferred← citeshttps://doi.org/10.69631/ipj.v1i3nr50openalex-snapshot
soil plastisphere: The nexus of microplastics, bacteria, and biofilms
inferred← citeshttps://doi.org/10.70675/1c8c154bz8d7dz4823z830bze930345b0345openalex-snapshot
Experimental methodologies to explore 3D development of biofilms in porous media
inferred← citeshttps://doi.org/10.7554/elife.21855openalex-snapshot
Flow environment and matrix structure interact to determine spatial competition in Pseudomonas aeruginosa biofilms
inferred← citeshttps://doi.org/10.7554/elife.26163openalex-snapshot
Structural dynamics of RbmA governs plasticity of Vibrio cholerae biofilms
inferred← citeshttps://doi.org/10.7554/elife.31082openalex-snapshot
Flipping the switch
inferred← citeshttps://doi.org/10.7554/elife.56533openalex-snapshot
Biofilms deform soft surfaces and disrupt epithelia
showing the first 200 of 201
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