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A Cell Atlas of the Adult Drosophila Midgut

https://doi.org/10.1073/pnas.1916820117

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Regional Cell Specific RNA Expression Profiling of FACS Isolated Drosophila Intestinal Cell Populations

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Two different thresholds of wingless signalling with distinct developmental consequences in the Drosophila midgut.

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vnd, a gene required for early neurogenesis of Drosophila, encodes a homeodomain protein.

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Age-related upregulation of Drosophila caudal gene via NF-κB in the adult posterior midgut

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Serotonin in the gut: Blessing or a curse

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Cytokine/Jak/Stat Signaling Mediates Regeneration and Homeostasis in the Drosophila Midgut

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Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency

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Morphological and Molecular Characterization of Adult Midgut Compartmentalization in Drosophila

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Control of Lipid Metabolism by Tachykinin in Drosophila

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Direct Sensing of Nutrients via a LAT1-like Transporter in Drosophila Insulin-Producing Cells

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Isoform-specific expression of the neuropeptide orcokinin in Drosophila melanogaster

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EGFR/Ras/MAPK Signaling Mediates Adult Midgut Epithelial Homeostasis and Regeneration in Drosophila

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Division of Labor: Roles of Groucho and CtBP in Notch-Mediated Lateral Inhibition that Controls Intestinal Stem Cell Differentiation in Drosophila

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Ubx dynamically regulates Dpp signaling by repressing Dad expression during copper cell regeneration in the adult Drosophila midgut

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odd-skipped is expressed in multiple tissues during Drosophila embryogenesis

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Peptidomics and Peptide Hormone Processing in theDrosophilaMidgut

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Gene Ontology: tool for the unification of biology

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Dimer ribbons of ATP synthase shape the inner mitochondrial membrane

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The adult Drosophila posterior midgut is maintained by pluripotent stem cells

inferredcites →https://doi.org/10.1038/nature04371openalex-snapshot

Evidence that stem cells reside in the adult Drosophila midgut epithelium

inferredcites →https://doi.org/10.1038/nature07329openalex-snapshot

Paracrine Wingless signalling controls self-renewal of Drosophila intestinal stem cells

inferredcites →https://doi.org/10.1038/nature16953openalex-snapshot

The sexual identity of adult intestinal stem cells controls organ size and plasticity

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A single-cell survey of the small intestinal epithelium

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Population snapshots predict early haematopoietic and erythroid hierarchies

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Mechanical regulation of stem-cell differentiation by the stretch-activated Piezo channel

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Spatial reconstruction of single-cell gene expression data

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Integrating single-cell transcriptomic data across different conditions, technologies, and species

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ATP synthase promotes germ cell differentiation independent of oxidative phosphorylation

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Massively parallel digital transcriptional profiling of single cells

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Power analysis of single-cell RNA-sequencing experiments

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Single-cell barcoding and sequencing using droplet microfluidics

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The WT1-like transcription factor Klumpfuss maintains lineage commitment of enterocyte progenitors in the Drosophila intestine

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Enteroendocrine cells switch hormone expression along the crypt-to-villus BMP signalling gradient

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Molecular mechanism and functional significance of acid generation in the Drosophila midgut

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Quiescent gastric stem cells maintain the adult Drosophila stomach

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O-Glycosylation regulates polarized secretion by modulating Tango1 stability

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The Neuroendocrine Protein 7B2 Suppresses the Aggregation of Neurodegenerative Disease-related Proteins

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Multipotent Drosophila Intestinal Stem Cells Specify Daughter Cell Fates by Differential Notch Signaling

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PAT-related amino acid transporters regulate growth via a novel mechanism that does not require bulk transport of amino acids

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The Hippo pathway regulates intestinal stem cell proliferation duringDrosophilaadult midgut regeneration

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EGF signaling regulates the proliferation of intestinal stem cells in Drosophila

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klumpfuss distinguishes stem cells from progenitor cells during asymmetric neuroblast division

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Notch cooperates with Lozenge/Runx to lock haemocytes into a differentiation programme

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Enteroendocrine cells are generated from stem cells through a distinct progenitor in the adult Drosophila posterior midgut

inferredcites →https://doi.org/10.1242/dev.114959openalex-snapshot

Generation of enteroendocrine cell diversity in midgut stem cell lineages

inferredcites →https://doi.org/10.1242/jcs.096800openalex-snapshot

A novel smooth septate junction-associated membrane protein, Snakeskin, is required for intestinal barrier function inDrosophila

inferredcites →https://doi.org/10.1242/jcs.112243openalex-snapshot

A novel protein complex, mesh-ssk, is required for septate junction formation indrosophilamidgut

inferredcites →https://doi.org/10.1242/jcs.180448openalex-snapshot

A tetraspanin regulates septate junction formation in Drosophila midgut

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Transcriptional Dynamics Elicited by a Short Pulse of Notch Activation Involves Feed-Forward Regulation by E(spl)/Hes Genes

inferredcites →https://doi.org/10.1371/journal.pgen.1005634openalex-snapshot

EGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated Genes

inferredcites →https://doi.org/10.1371/journal.pgen.1007618openalex-snapshot

The thirsty fly: Ion transport peptide (ITP) is a novel endocrine regulator of water homeostasis in Drosophila

inferredcites →https://doi.org/10.1371/journal.pone.0012257openalex-snapshot

LRCH Proteins: A Novel Family of Cytoskeletal Regulators

inferredcites →https://doi.org/10.1371/journal.pone.0029022openalex-snapshot

Heterogeneous Expression of Drosophila Gustatory Receptors in Enteroendocrine Cells

inferredcites →https://doi.org/10.1371/journal.pone.0133017openalex-snapshot

CCHamide-2 Is an Orexigenic Brain-Gut Peptide in Drosophila

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A Systematic Analysis of Drosophila Regulatory Peptide Expression in Enteroendocrine Cells

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Escargot maintains stemness and suppresses differentiation in Drosophila intestinal stem cells

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The Drosophila Prosecretory Transcription Factor dimmed Is Dynamically Regulated in Adult Enteroendocrine Cells and Protects Against Gram-Negative Infection

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Regulation of Drosophila Intestinal Stem Cell Proliferation by Enterocyte Mitochondrial Pyruvate Metabolism

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The ModERN Resource: Genome-Wide Binding Profiles for Hundreds of Drosophila and Caenorhabditis elegans Transcription Factors

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UMAP: Uniform Manifold Approximation and Projection

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Energy Metabolism Plays a Critical Role in Stem Cell Maintenance and Differentiation

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Mitochondrial Dynamics in Stem Cells and Differentiation

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UMAP: Uniform Manifold Approximation and Projection for Dimension Reduction

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GLAD: an Online Database of G ene L ist A nnotation for D rosophila

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Physiological and stem cell compartmentalization within the Drosophila midgut

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inferred← citeshttps://doi.org/10.1016/j.ibmb.2020.103496openalex-snapshot

Heterogeneity of midgut cells and their differential responses to blood meal ingestion by the mosquito, Aedes aegypti

inferred← citeshttps://doi.org/10.1016/j.ibmb.2020.103510openalex-snapshot

Functional characterization and transcriptomic profiling of a spheroid-forming midgut cell line from Helicoverpa zea (Lepidoptera: Noctuidae)

inferred← citeshttps://doi.org/10.1016/j.ibmb.2023.104043openalex-snapshot

Single-nucleus sequencing of silkworm larval midgut reveals the immune escape strategy of BmNPV in the midgut during the late stage of infection

inferred← citeshttps://doi.org/10.1016/j.ibmb.2025.104399openalex-snapshot

Single-cell transcriptomic profiling reveals diet-dependent dynamics of glucosinolate sulfatases expression and cellular origin in the midgut of Plutella xylostella

inferred← citeshttps://doi.org/10.1016/j.isci.2022.104626openalex-snapshot

Biogenic action of Lactobacillus plantarum SBT2227 promotes sleep in Drosophila melanogaster

inferred← citeshttps://doi.org/10.1016/j.isci.2023.108624openalex-snapshot

Crosstalk between chromatin and Shavenbaby defines transcriptional output along the Drosophila intestinal stem cell lineage

inferred← citeshttps://doi.org/10.1016/j.isci.2024.110353openalex-snapshot

Zika virus exists in enterocytes and enteroendocrine cells of the Aedes aegypti midgut

inferred← citeshttps://doi.org/10.1016/j.isci.2025.113090openalex-snapshot

Polyclonality and metabolic heterogeneity in a colorectal tumor model

inferred← citeshttps://doi.org/10.1016/j.jare.2026.02.019openalex-snapshot

Identification of key midgut cell clusters Co-responding fungal and viral infections in silkworms

inferred← citeshttps://doi.org/10.1016/j.jgg.2025.05.003openalex-snapshot

Two-pore-domain potassium channel Sandman regulates intestinal stem cell homeostasis and tumorigenesis in Drosophila melanogaster

inferred← citeshttps://doi.org/10.1016/j.mce.2023.112108openalex-snapshot

The neuroendocrine and endocrine systems in insect – Historical perspective and overview

inferred← citeshttps://doi.org/10.1016/j.molmet.2025.102312openalex-snapshot

Gut hormone signaling drives sex differences in metabolism and behavior

inferred← citeshttps://doi.org/10.1016/j.scitotenv.2025.179956openalex-snapshot

Cytotoxic effects of leachate from landfill tanks: A study on the model species Drosophila melanogaster

inferred← citeshttps://doi.org/10.1016/j.stemcr.2021.04.006openalex-snapshot

Neuroglian regulates Drosophila intestinal stem cell proliferation through enhanced signaling via the epidermal growth factor receptor

inferred← citeshttps://doi.org/10.1016/j.stemcr.2022.02.009openalex-snapshot

Immune regulation of intestinal-stem-cell function in Drosophila

inferred← citeshttps://doi.org/10.1016/j.tcb.2021.01.003openalex-snapshot

The Role of Organelles in Intestinal Function, Physiology, and Disease

inferred← citeshttps://doi.org/10.1016/j.tcb.2022.10.003openalex-snapshot

Bioelectric regulation of intestinal stem cells

inferred← citeshttps://doi.org/10.1016/j.tig.2021.04.008openalex-snapshot

Evolutionary cell type mapping with single-cell genomics

inferred← citeshttps://doi.org/10.1016/j.xgen.2025.100924openalex-snapshot

Single-cell transcriptional landscapes of Aedes aegypti midgut and fat body after a bloodmeal

inferred← citeshttps://doi.org/10.1016/j.xpro.2022.101417openalex-snapshot

Isolation and RNA sequencing of single nuclei from Drosophila tissues

inferred← citeshttps://doi.org/10.1016/j.yexcr.2021.112838openalex-snapshot

Drosophila intestinal homeostasis requires CTP synthase

inferred← citeshttps://doi.org/10.1016/j.ygeno.2021.08.015openalex-snapshot

Cell type diversity in scallop adductor muscles revealed by single-cell RNA-Seq

inferred← citeshttps://doi.org/10.1016/j.ygeno.2024.110898openalex-snapshot

Deciphering cellular heterogeneity in Spodoptera frugiperda midgut cell line through single cell RNA sequencing

inferred← citeshttps://doi.org/10.1038/s41380-023-02314-6openalex-snapshot

The effects of methylphenidate and atomoxetine on Drosophila brain at single-cell resolution and potential drug repurposing for ADHD treatment

inferred← citeshttps://doi.org/10.1038/s41419-023-06215-yopenalex-snapshot

Control of TGFβ signalling by ubiquitination independent function of E3 ubiquitin ligase TRIP12

inferred← citeshttps://doi.org/10.1038/s41420-023-01391-4openalex-snapshot

Single-cell RNA sequencing reveals cell landscape following antimony exposure during spermatogenesis in Drosophila testes

inferred← citeshttps://doi.org/10.1038/s41421-023-00541-3openalex-snapshot

Gut AstA mediates sleep deprivation-induced energy wasting in Drosophila

inferred← citeshttps://doi.org/10.1038/s41467-021-25146-wopenalex-snapshot

The sugar-responsive enteroendocrine neuropeptide F regulates lipid metabolism through glucagon-like and insulin-like hormones in Drosophila melanogaster

inferred← citeshttps://doi.org/10.1038/s41467-022-28268-xopenalex-snapshot

The gut hormone Allatostatin C/Somatostatin regulates food intake and metabolic homeostasis under nutrient stress

inferred← citeshttps://doi.org/10.1038/s41467-022-34270-0openalex-snapshot

A hierarchical transcription factor cascade regulates enteroendocrine cell diversity and plasticity in Drosophila

inferred← citeshttps://doi.org/10.1038/s41467-023-37876-0openalex-snapshot

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

inferred← citeshttps://doi.org/10.1038/s41467-023-43550-2openalex-snapshot

Early-adult methionine restriction reduces methionine sulfoxide and extends lifespan in Drosophila

inferred← citeshttps://doi.org/10.1038/s41467-024-45942-4openalex-snapshot

The emergence of circadian timekeeping in the intestine

inferred← citeshttps://doi.org/10.1038/s41467-024-46956-8openalex-snapshot

Cell-fate conversion of intestinal cells in adult Drosophila midgut by depleting a single transcription factor

inferred← citeshttps://doi.org/10.1038/s41467-024-47465-4openalex-snapshot

Dietary L-Glu sensing by enteroendocrine cells adjusts food intake via modulating gut PYY/NPF secretion

inferred← citeshttps://doi.org/10.1038/s41467-024-48851-8openalex-snapshot

A nutrient responsive lipase mediates gut-brain communication to regulate insulin secretion in Drosophila

inferred← citeshttps://doi.org/10.1038/s41467-026-68876-5openalex-snapshot

The Drosophila proventriculus lacks stem cells but compensates for age-related cell loss via endoreplication-mediated cell growth

inferred← citeshttps://doi.org/10.1038/s41467-026-70704-9openalex-snapshot

Frazzled/DCC directs spatial progenitor integration ensuring steady-state intestinal turnover

inferred← citeshttps://doi.org/10.1038/s41586-022-04408-7openalex-snapshot

A nutrient-specific gut hormone arbitrates between courtship and feeding

inferred← citeshttps://doi.org/10.1038/s41586-023-06039-yopenalex-snapshot

A phosphate-sensing organelle regulates phosphate and tissue homeostasis

inferred← citeshttps://doi.org/10.1038/s41586-025-09653-0openalex-snapshot

Mapping Plasmodium transitions and interactions in the Anopheles female

inferred← citeshttps://doi.org/10.1038/s41586-026-10494-8openalex-snapshot

Adaptive cellular evolution in the intestine of hyperdiverse cichlid fishes

inferred← citeshttps://doi.org/10.1038/s41597-024-03432-8openalex-snapshot

A cell atlas of the adult female Aedes aegypti midgut revealed by single-cell RNA sequencing

inferred← citeshttps://doi.org/10.1038/s41597-025-04520-zopenalex-snapshot

A comprehensive cell atlas of fall armyworm (Spodoptera frugiperda) larval gut and fat body via snRNA-Seq

inferred← citeshttps://doi.org/10.1038/s41597-025-06290-0openalex-snapshot

A single-cell transcriptomic dataset of enterocyte-specific HHEX knockdown in the Drosophila larval midgut

inferred← citeshttps://doi.org/10.1038/s41598-025-17336-zopenalex-snapshot

Establishment of Drosophila intestinal cell lines as tools for multiomic screening and deciphering intestinal biology

inferred← citeshttps://doi.org/10.1038/s41598-025-31545-6openalex-snapshot

Feeding Drosophila highly radioresistant fungi improves survival and gut morphology following acute gamma radiation exposure

inferred← citeshttps://doi.org/10.1038/s41598-025-98888-yopenalex-snapshot

Characterization of transcriptomics during aging and genes required for lifespan in Drosophila intestine

inferred← citeshttps://doi.org/10.1038/s42255-022-00672-zopenalex-snapshot

A gut-derived hormone suppresses sugar appetite and regulates food choice in Drosophila

inferred← citeshttps://doi.org/10.1038/s42255-025-01267-0openalex-snapshot

Protein-responsive gut hormone tachykinin directs food choice and impacts lifespan

inferred← citeshttps://doi.org/10.1038/s44318-026-00808-xopenalex-snapshot

Autoinhibitory feedback preserves intestinal stem cell maintenance and fate commitment

inferred← citeshttps://doi.org/10.1038/s44319-026-00837-xopenalex-snapshot

Psc and Su(z)2 safeguard intestinal stem cell identity and prevent chinmo-dependent tumorigenesis

inferred← citeshttps://doi.org/10.1039/c9mt00218aopenalex-snapshot

Intestinal response to dietary manganese depletion in Drosophila

inferred← citeshttps://doi.org/10.1039/d3na00684kopenalex-snapshot

Nitrogen-vacancy center magnetic imaging of Fe 3 O 4 nanoparticles inside the gastrointestinal tract of Drosophila melanogaster

inferred← citeshttps://doi.org/10.1073/pnas.2203179119openalex-snapshot

Transcriptional and functional motifs defining renal function revealed by single-nucleus RNA sequencing

inferred← citeshttps://doi.org/10.1073/pnas.2304730120openalex-snapshot

split-intein Gal4 provides intersectional genetic labeling that is repressible by Gal80

inferred← citeshttps://doi.org/10.1073/pnas.2411987121openalex-snapshot

Gut-to-brain regulation of Drosophila aging through neuropeptide F, insulin, and juvenile hormone

inferred← citeshttps://doi.org/10.1080/01677063.2020.1853722openalex-snapshot

Identification and characterization of GAL4 drivers that mark distinct cell types and regions in the Drosophila adult gut

inferred← citeshttps://doi.org/10.1080/01677063.2021.1941946openalex-snapshot

Expression of the foraging gene in adult Drosophila melanogaster

inferred← citeshttps://doi.org/10.1080/01677063.2021.1989425openalex-snapshot

Spatiotemporal organization of enteroendocrine peptide expression in Drosophila

inferred← citeshttps://doi.org/10.1080/01677063.2022.2115040openalex-snapshot

History of Drosophila neurogenetic research in South Korea

inferred← citeshttps://doi.org/10.1080/19336934.2022.2061834openalex-snapshot

Interorgan communication through peripherally derived peptide hormones inDrosophila

inferred← citeshttps://doi.org/10.1080/19336934.2022.2066952openalex-snapshot

Cellular mechanisms underlying adult tissue plasticity in Drosophila

inferred← citeshttps://doi.org/10.1080/19336934.2026.2624185openalex-snapshot

Systematic generation of Drosophila Wnt transgenes enables the characterization of canonical Wnt signaling

inferred← citeshttps://doi.org/10.1080/19490976.2023.2208503openalex-snapshot

The role of Drosophila microbiota in gut homeostasis and immunity

inferred← citeshttps://doi.org/10.1080/19490976.2025.2573045openalex-snapshot

Microbiota shape the colon epithelium controlling inter-crypt absorptive goblet cells via butyrate–GP R109A signalling

inferred← citeshttps://doi.org/10.1083/jcb.202506084openalex-snapshot

A regional regulatory axis shapes enteroendocrine cell morphology and function

inferred← citeshttps://doi.org/10.1091/mbc.e24-03-0143openalex-snapshot

Integration of signal transduction pathways in sensory epithelial enteroendocrine cells

inferred← citeshttps://doi.org/10.1093/g3journal/jkac102openalex-snapshot

Identification of novel split-GAL4 drivers for the characterization of enteroendocrine cells in the Drosophila melanogaster midgut

inferred← citeshttps://doi.org/10.1093/g3journal/jkad178openalex-snapshot

Cellular heterogeneity of the developing worker honey bee (Apis mellifera) pupa: a single cell transcriptomics analysis

inferred← citeshttps://doi.org/10.1093/genetics/iyab019openalex-snapshot

Methods and tools for spatial mapping of single-cell RNAseq clusters inDrosophila

inferred← citeshttps://doi.org/10.1093/genetics/iyab031openalex-snapshot

Drosophila MOV10 regulates the termination of midgut regeneration

inferred← citeshttps://doi.org/10.1093/genetics/iyab235openalex-snapshot

FlyPhoneDB: an integrated web-based resource for cell–cell communication prediction in Drosophila

inferred← citeshttps://doi.org/10.1093/genetics/iyac099openalex-snapshot

The RNA-binding protein Swm is critical for Drosophila melanogaster intestinal progenitor cell maintenance

inferred← citeshttps://doi.org/10.1093/genetics/iyad004openalex-snapshot

A modERN resource: identification of Drosophila transcription factor candidate target genes using RNAi

inferred← citeshttps://doi.org/10.1093/genetics/iyad040openalex-snapshot

Long noncoding RNA CR46040 is essential for injury-stimulated regeneration of intestinal stem cells in Drosophila

inferred← citeshttps://doi.org/10.1093/genetics/iyaf234openalex-snapshot

Single-cell transcriptome defines cell-type repertoire of adult Daphnia magna

inferred← citeshttps://doi.org/10.1093/molbev/msag170openalex-snapshot

Parallel expansion of trehalose transporter genes integrates intestinal energy metabolism with developmental growth in lepidopteran insects

inferred← citeshttps://doi.org/10.1093/nar/gkaa412openalex-snapshot

ASAP 2020 update: an open, scalable and interactive web-based portal for (single-cell) omics analyses

inferred← citeshttps://doi.org/10.1093/nar/gkaa936openalex-snapshot

FlyRNAi.org—the database of the Drosophila RNAi screening center and transgenic RNAi project: 2021 update

inferred← citeshttps://doi.org/10.1093/nar/gkab971openalex-snapshot

FlyAtlas 2 in 2022: enhancements to the Drosophila melanogaster expression atlas

inferred← citeshttps://doi.org/10.1093/nar/gkae917openalex-snapshot

FlyRNAi.org 2025 update—expanded resources for new technologies and species

inferred← citeshttps://doi.org/10.1101/2020.07.01.182352openalex-snapshot

Heterogeneity in the response of different subtypes of Drosophila melanogaster enteroendocrine cells to viral infections

inferred← citeshttps://doi.org/10.1101/2020.10.02.323444openalex-snapshot

ROS-dependent innate immune mechanisms control Staphylococcus aureus MRSA virulence in the Drosophila larval model

inferred← citeshttps://doi.org/10.1101/2020.12.05.412874openalex-snapshot

The gut hormone Allatostatin C regulates food intake and metabolic homeostasis under nutrient stress

inferred← citeshttps://doi.org/10.1101/2020.12.20.423699openalex-snapshot

Alternate Grainy head isoforms regulate Drosophila midgut intestinal stem cell differentiation

inferred← citeshttps://doi.org/10.1101/2021.09.03.458871openalex-snapshot

A cell atlas of the fly kidney

inferred← citeshttps://doi.org/10.1101/2021.10.21.465301openalex-snapshot

High-resolution spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae

inferred← citeshttps://doi.org/10.1101/2021.12.17.473216openalex-snapshot

Kismet/CHD7/CHD8 affects gut biomechanics, the gut microbiome, and gut-brain axis in Drosophila melanogaster

inferred← citeshttps://doi.org/10.1101/2022.01.10.475734openalex-snapshot

TrpA1 is a shear stress mechanosensing channel regulating intestinal homeostasis in Drosophila

inferred← citeshttps://doi.org/10.1101/2022.03.02.482605openalex-snapshot

A gut-derived hormone switches dietary preference after mating in Drosophila

inferred← citeshttps://doi.org/10.1101/2022.06.27.497786openalex-snapshot

Prioritizing transcription factor perturbations from single-cell transcriptomics

inferred← citeshttps://doi.org/10.1101/2022.09.29.510182openalex-snapshot

Relish/NF-κB acts in intestinal stem cells to promote epithelial repair in Drosophila

inferred← citeshttps://doi.org/10.1101/2022.10.07.511357openalex-snapshot

Charting the development of Drosophila leg sensory organs at single-cell resolution

inferred← citeshttps://doi.org/10.1101/2023.02.16.528767openalex-snapshot

Recognition of commensal bacterial peptidoglycans defines Drosophila gut homeostasis and lifespan

inferred← citeshttps://doi.org/10.1101/2023.03.15.532514openalex-snapshot

Early-adult methionine restriction reduces methionine sulfoxide and extends lifespan in Drosophila

inferred← citeshttps://doi.org/10.1101/2023.03.24.534001openalex-snapshot

split-intein Gal4 provides intersectional genetic labeling that is fully repressible by Gal80

inferred← citeshttps://doi.org/10.1101/2023.05.08.539820openalex-snapshot

Nutrient-driven dedifferentiation of enteroendocrine cells promotes adaptive intestinal growth

inferred← citeshttps://doi.org/10.1101/2023.06.02.543385openalex-snapshot

A mitochondrial sirtuin shapes the intestinal microbiota by controlling lysozyme expression

inferred← citeshttps://doi.org/10.1101/2023.08.14.553227openalex-snapshot

Epithelial Ca 2+ waves triggered by enteric neurons heal the gut

inferred← citeshttps://doi.org/10.1101/2023.10.18.562868openalex-snapshot

A specific innate immune response silences the virulence of Pseudomonas aeruginosa in a latent infection model in the Drosophila melanogaster host

inferred← citeshttps://doi.org/10.1101/2024.02.05.578891openalex-snapshot

Restraining Wnt activation and intestinal tumorigenesis by a Rab35 dependent GTPase relay

inferred← citeshttps://doi.org/10.1101/2024.02.06.577903openalex-snapshot

A single-cell 3D spatiotemporal multi-omics atlas from Drosophila embryogenesis to metamorphosis

inferred← citeshttps://doi.org/10.1101/2024.02.13.580057openalex-snapshot

Variations in polarized trafficking of viral envelope proteins from insect-specific and insect-vectored viruses in insect midgut and salivary gland cells

inferred← citeshttps://doi.org/10.1101/2024.02.15.580237openalex-snapshot

The transmembrane protein Syndecan regulates stem cell nuclear properties and cell maintenance

inferred← citeshttps://doi.org/10.1101/2024.06.26.600832openalex-snapshot

Gut-to-brain regulation of Drosophila aging through neuropeptide F, insulin and juvenile hormone

inferred← citeshttps://doi.org/10.1101/2024.08.05.606739openalex-snapshot

The transcription factor Chronophage/BCL11A/B promotes intestinal stem cell proliferation and endocrine differentiation

inferred← citeshttps://doi.org/10.1101/2024.09.08.611891openalex-snapshot

Proliferation and differentiation of intestinal stem cells depends on the zinc finger transcription factor BCL11/Chronophage

inferred← citeshttps://doi.org/10.1101/2024.09.10.612352openalex-snapshot

Neuroendocrine Control of Intestinal Regeneration Through the Vascular Niche in Drosophila

inferred← citeshttps://doi.org/10.1101/2024.11.08.622039openalex-snapshot

Single-cell transcriptional landscapes of Aedes aegypti midgut and fat body after a bloodmeal

inferred← citeshttps://doi.org/10.1101/2024.11.28.625862openalex-snapshot

Adaptive cellular evolution in the intestinal tracts of hyperdiverse African cichlid fishes

inferred← citeshttps://doi.org/10.1101/2025.01.26.634899openalex-snapshot

BubR1 and Mad2 regulate adult midgut remodeling in Drosophila diapause

inferred← citeshttps://doi.org/10.1101/2025.05.27.656384openalex-snapshot

Establishment of Drosophila Intestinal Cell Lines

inferred← citeshttps://doi.org/10.1101/2025.08.27.672561openalex-snapshot

Spatiotemporal WNT and BMP gradients orchestrate regional enteroendocrine cell diversity along the Drosophila midgut

inferred← citeshttps://doi.org/10.1101/2025.11.21.689716openalex-snapshot

Trithorax balances ISC fate decisions via Ptx1-mediated repression of EE specification

inferred← citeshttps://doi.org/10.1101/685347openalex-snapshot

A bHLH interaction code controls bipotential differentiation and self-renewal in the Drosophila gut

inferred← citeshttps://doi.org/10.1101/721662openalex-snapshot

Immune Regulation of Intestinal Stem Cell Proliferation and Differentiation in Drosophila

inferred← citeshttps://doi.org/10.1101/cshperspect.a040915openalex-snapshot

Insect Gut Regeneration

inferred← citeshttps://doi.org/10.1109/bibm47256.2019.8983083openalex-snapshot

Computational Methods for scRNA-seq Analysis at Cell Level

inferred← citeshttps://doi.org/10.1111/1744-7917.13001openalex-snapshot

Comparative transcriptome analysis reveals regional specialization of gene expression in larval silkworm (Bombyx mori) midgut

inferred← citeshttps://doi.org/10.1111/1744-7917.13464openalex-snapshot

Single‐nucleus RNA sequencing reveals midgut cellular heterogeneity and transcriptional profiles in Bombyx mori cytoplasmic polyhedrosis virus infection

inferred← citeshttps://doi.org/10.1111/1744-7917.70112openalex-snapshot

Mating affects dopamine signaling in Drosophila melanogaster females

inferred← citeshttps://doi.org/10.1111/1744-7917.70157openalex-snapshot

Gut microbiota shape gene regulatory networks to direct intestinal stem cell differentiation trajectories in Apis mellifera

inferred← citeshttps://doi.org/10.1111/1744-7917.70279openalex-snapshot

Gut single‐nucleus RNA sequencing reveals that NPF receptor regulates feeding behavior through mitochondrial energy metabolism

inferred← citeshttps://doi.org/10.1111/febs.15910openalex-snapshot

Microbial recognition regulates intestinal epithelial growth in homeostasis and disease

inferred← citeshttps://doi.org/10.1111/febs.16067openalex-snapshot

The specification and function of enteroendocrine cells in Drosophila and mammals: a comparative review

inferred← citeshttps://doi.org/10.1111/gtc.70005openalex-snapshot

Regulation of Gut Starvation Responses Through Drosophila NP3253 Neurons

inferred← citeshttps://doi.org/10.1126/sciadv.adc9660openalex-snapshot

TrpA1 is a shear stress mechanosensing channel regulating intestinal stem cell proliferation in Drosophila

inferred← citeshttps://doi.org/10.1126/sciadv.ady7272openalex-snapshot

Drosophila and mouse intestinal stem cells are spatiotemporally specified by Notch suppression and Wnt activation

inferred← citeshttps://doi.org/10.1126/science.abk2432openalex-snapshot

Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly

inferred← citeshttps://doi.org/10.1126/science.abn5800openalex-snapshot

The continuum of Drosophila embryonic development at single-cell resolution

inferred← citeshttps://doi.org/10.1128/jvi.00540-24openalex-snapshot

Viral and cellular determinants of polarized trafficking of viral envelope proteins from insect-specific and insect-vectored viruses in insect midgut and salivary gland cells

inferred← citeshttps://doi.org/10.1128/mbio.00276-21openalex-snapshot

Reactive Oxygen Species-Dependent Innate Immune Mechanisms Control Methicillin-Resistant Staphylococcus aureus Virulence in the Drosophila Larval Model

inferred← citeshttps://doi.org/10.1152/physiol.00030.2024openalex-snapshot

The Integrative Physiology of Hormone Signaling: Insights from Insect Models

inferred← citeshttps://doi.org/10.1186/s11689-021-09378-xopenalex-snapshot

The gut-microbiota-brain axis in autism: what Drosophila models can offer?

inferred← citeshttps://doi.org/10.1186/s12859-024-05912-5openalex-snapshot

Answering open questions in biology using spatial genomics and structured methods

inferred← citeshttps://doi.org/10.1186/s12915-022-01479-wopenalex-snapshot

The genomic basis of copper tolerance in Drosophila is shaped by a complex interplay of regulatory and environmental factors

inferred← citeshttps://doi.org/10.1186/s42523-025-00431-xopenalex-snapshot

Mitochondrial sirtuin 4 shapes the intestinal microbiota of Drosophila by controlling lysozyme expression

inferred← citeshttps://doi.org/10.1242/bio.062025openalex-snapshot

Stem cell-specific NF-κB is required for stem cell survival and epithelial regeneration upon intestinal damage

inferred← citeshttps://doi.org/10.1242/dev.196568openalex-snapshot

I-KCKT allows dissection-free RNA profiling of adult Drosophila intestinal progenitor cells

inferred← citeshttps://doi.org/10.1242/dev.204794openalex-snapshot

Toll signalling controls intestinal regeneration in Drosophila

inferred← citeshttps://doi.org/10.1242/dev.205225openalex-snapshot

Xrp1 drives damage-induced cellular plasticity of enteroendocrine cells in the adult Drosophila midgut

inferred← citeshttps://doi.org/10.1242/dmm.049332openalex-snapshot

Investigating local and systemic intestinal signalling in health and disease with Drosophila

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