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Immune Regulation of Intestinal Stem Cell Proliferation and Differentiation in Drosophila

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/0016-5085(94)90526-6openalex-snapshot
Microflora modulates endocrine cells in the gastrointestinal mucosa of the rat
inferredcites →https://doi.org/10.1016/bs.ai.2014.11.003openalex-snapshot
Epithelial Cell Contributions to Intestinal Immunity
inferredcites →https://doi.org/10.1016/j.cell.2009.05.014openalex-snapshot
Cytokine/Jak/Stat Signaling Mediates Regeneration and Homeostasis in the Drosophila Midgut
inferredcites →https://doi.org/10.1016/j.cell.2013.12.018openalex-snapshot
PGRP-SC2 Promotes Gut Immune Homeostasis to Limit Commensal Dysbiosis and Extend Lifespan
inferredcites →https://doi.org/10.1016/j.cell.2018.10.008openalex-snapshot
T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation
inferredcites →https://doi.org/10.1016/j.celrep.2013.04.001openalex-snapshot
Morphological and Molecular Characterization of Adult Midgut Compartmentalization in Drosophila
inferredcites →https://doi.org/10.1016/j.celrep.2014.05.024openalex-snapshot
Slit/Robo Signaling Regulates Cell Fate Decisions in the Intestinal Stem Cell Lineage of Drosophila
inferredcites →https://doi.org/10.1016/j.celrep.2015.06.009openalex-snapshot
Regional Cell-Specific Transcriptome Mapping Reveals Regulatory Complexity in the Adult Drosophila Midgut
inferredcites →https://doi.org/10.1016/j.celrep.2015.08.004openalex-snapshot
Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality
inferredcites →https://doi.org/10.1016/j.celrep.2017.07.078openalex-snapshot
Constitutive Immune Activity Promotes Tumorigenesis in Drosophila Intestinal Progenitor Cells
inferredcites →https://doi.org/10.1016/j.celrep.2017.08.059openalex-snapshot
Piwi Is Required to Limit Exhaustion of Aging Somatic Stem Cells
inferredcites →https://doi.org/10.1016/j.celrep.2019.11.048openalex-snapshot
The Cellular Diversity and Transcription Factor Code of Drosophila Enteroendocrine Cells
inferredcites →https://doi.org/10.1016/j.celrep.2019.12.094openalex-snapshot
Vibrio cholerae-Symbiont Interactions Inhibit Intestinal Repair in Drosophila
inferredcites →https://doi.org/10.1016/j.chom.2008.07.004openalex-snapshot
PIMS Modulates Immune Tolerance by Negatively Regulating Drosophila Innate Immune Signaling
inferredcites →https://doi.org/10.1016/j.chom.2009.01.003openalex-snapshot
Drosophila Intestinal Response to Bacterial Infection: Activation of Host Defense and Stem Cell Proliferation
inferredcites →https://doi.org/10.1016/j.chom.2012.06.002openalex-snapshot
Peptidoglycan Sensing by the Receptor PGRP-LE in the Drosophila Gut Induces Immune Responses to Infectious Bacteria and Tolerance to Microbiota
inferredcites →https://doi.org/10.1016/j.chom.2014.05.003openalex-snapshot
The Cytosolic Bacterial Peptidoglycan Sensor Nod2 Affords Stem Cell Protection and Links Microbes to Gut Epithelial Regeneration
inferredcites →https://doi.org/10.1016/j.chom.2014.10.006openalex-snapshot
The Acetate Switch of an Intestinal Pathogen Disrupts Host Insulin Signaling and Lipid Metabolism
inferredcites →https://doi.org/10.1016/j.chom.2016.08.003openalex-snapshot
Signal Integration by the IκB Protein Pickle Shapes Drosophila Innate Host Defense
inferredcites →https://doi.org/10.1016/j.chom.2019.07.001openalex-snapshot
Sugar Alcohols of Polyol Pathway Serve as Alarmins to Mediate Local-Systemic Innate Immune Communication in Drosophila
inferredcites →https://doi.org/10.1016/j.cmet.2007.06.006openalex-snapshot
Increased Internal and External Bacterial Load during Drosophila Aging without Life-Span Trade-Off
inferredcites →https://doi.org/10.1016/j.cmet.2018.05.026openalex-snapshot
The Drosophila Immune Deficiency Pathway Modulates Enteroendocrine Function and Host Metabolism
inferredcites →https://doi.org/10.1016/j.dci.2016.01.001openalex-snapshot
Bacteria sensing mechanisms in Drosophila gut: Local and systemic consequences
inferredcites →https://doi.org/10.1016/j.dci.2016.02.020openalex-snapshot
The zebrafish as a model to study intestinal inflammation
inferredcites →https://doi.org/10.1016/j.dci.2017.11.008openalex-snapshot
Beyond immunity: The Imd pathway as a coordinator of host defense, organismal physiology and behavior
inferredcites →https://doi.org/10.1016/j.devcel.2018.08.013openalex-snapshot
Dietary Lipids Modulate Notch Signaling and Influence Adult Intestinal Development and Metabolism in Drosophila
inferredcites →https://doi.org/10.1016/j.devcel.2019.04.009openalex-snapshot
NF-κB Shapes Metabolic Adaptation by Attenuating Foxo-Mediated Lipolysis in Drosophila
inferredcites →https://doi.org/10.1016/j.gde.2012.04.002openalex-snapshot
Intestinal stem cell function in Drosophila and mice
inferredcites →https://doi.org/10.1016/j.immuni.2006.02.012openalex-snapshot
The Drosophila Amidase PGRP-LB Modulates the Immune Response to Bacterial Infection
inferredcites →https://doi.org/10.1016/j.immuni.2011.09.018openalex-snapshot
Negative Regulation by Amidase PGRPs Shapes the Drosophila Antibacterial Response and Protects the Fly from Innocuous Infection
inferredcites →https://doi.org/10.1016/j.immuni.2018.04.010openalex-snapshot
Cell-Specific Imd-NF-κB Responses Enable Simultaneous Antibacterial Immunity and Intestinal Epithelial Cell Shedding upon Bacterial Infection
inferredcites →https://doi.org/10.1016/j.immuni.2018.07.016openalex-snapshot
A Map of Toll-like Receptor Expression in the Intestinal Epithelium Reveals Distinct Spatial, Cell Type-Specific, and Temporal Patterns
inferredcites →https://doi.org/10.1016/j.immuni.2018.09.017openalex-snapshot
Microbiota-Derived Lactate Activates Production of Reactive Oxygen Species by the Intestinal NADPH Oxidase Nox and Shortens Drosophila Lifespan
inferredcites →https://doi.org/10.1016/j.immuni.2019.06.003openalex-snapshot
T Cell Recruitment to the Intestinal Stem Cell Compartment Drives Immune-Mediated Intestinal Damage after Allogeneic Transplantation
inferredcites →https://doi.org/10.1016/j.immuni.2019.08.020openalex-snapshot
Nephrocytes Remove Microbiota-Derived Peptidoglycan from Systemic Circulation to Maintain Immune Homeostasis
inferredcites →https://doi.org/10.1016/j.it.2018.12.008openalex-snapshot
The Intestinal Epithelium: Central Coordinator of Mucosal Immunity
inferredcites →https://doi.org/10.1016/j.mod.2004.10.009openalex-snapshot
Intestinal growth and differentiation in zebrafish
inferredcites →https://doi.org/10.1016/j.molcel.2009.12.036openalex-snapshot
Caspase-Mediated Cleavage, IAP Binding, and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NF-κB Signaling
inferredcites →https://doi.org/10.1016/j.stem.2009.01.009openalex-snapshot
Intestinal Stem Cells in Mammals and Drosophila
inferredcites →https://doi.org/10.1016/j.ydbio.2011.03.018openalex-snapshot
EGFR, Wingless and JAK/STAT signaling cooperatively maintain Drosophila intestinal stem cells
inferredcites →https://doi.org/10.1038/35079107openalex-snapshot
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
inferredcites →https://doi.org/10.1038/35079114openalex-snapshot
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
inferredcites →https://doi.org/10.1038/ismej.2017.28openalex-snapshot
The role of adaptive immunity as an ecological filter on the gut microbiota in zebrafish
inferredcites →https://doi.org/10.1038/labinvest.2010.100openalex-snapshot
Toll-like receptor 4 differentially regulates epidermal growth factor-related growth factors in response to intestinal mucosal injury
inferredcites →https://doi.org/10.1038/mi.2015.112openalex-snapshot
Intestinal FoxO signaling is required to survive oral infection in Drosophila
inferredcites →https://doi.org/10.1038/nature04333openalex-snapshot
The adult Drosophila posterior midgut is maintained by pluripotent stem cells
inferredcites →https://doi.org/10.1038/nature04371openalex-snapshot
Evidence that stem cells reside in the adult Drosophila midgut epithelium
inferredcites →https://doi.org/10.1038/ncb1500openalex-snapshot
Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells
inferredcites →https://doi.org/10.1038/ncomms5560openalex-snapshot
Automated monitoring and quantitative analysis of feeding behaviour in Drosophila
inferredcites →https://doi.org/10.1038/ni1356openalex-snapshot
PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan
inferredcites →https://doi.org/10.1038/nrm3721openalex-snapshot
Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration
inferredcites →https://doi.org/10.1038/nrmicro3074openalex-snapshot
Gut homeostasis in a microbial world: insights from Drosophila melanogaster
inferredcites →https://doi.org/10.1038/onc.2012.581openalex-snapshot
Constitutive TLR4 signalling in intestinal epithelium reduces tumor load by increasing apoptosis in APCMin/+ mice
inferredcites →https://doi.org/10.1038/s41467-019-08982-9openalex-snapshot
Loss of a proteostatic checkpoint in intestinal stem cells contributes to age-related epithelial dysfunction
inferredcites →https://doi.org/10.1053/j.gastro.2006.06.017openalex-snapshot
Cox-2 Is Regulated by Toll-Like Receptor-4 (TLR4) Signaling: Role in Proliferation and Apoptosis in the Intestine
inferredcites →https://doi.org/10.1053/j.gastro.2011.06.003openalex-snapshot
Notch: Architect, Landscaper, and Guardian of the Intestine
inferredcites →https://doi.org/10.1073/pnas.1000072107openalex-snapshot
Epithelial cell proliferation in the developing zebrafish intestine is regulated by the Wnt pathway and microbial signaling via Myd88
inferredcites →https://doi.org/10.1073/pnas.1012759107openalex-snapshot
Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways
inferredcites →https://doi.org/10.1073/pnas.1035902100openalex-snapshot
Caspase-mediated processing of the Drosophila NF-κB factor Relish
inferredcites →https://doi.org/10.1073/pnas.1902788117openalex-snapshot
Innate immune receptor NOD2 mediates LGR5 + intestinal stem cell protection against ROS cytotoxicity via mitophagy stimulation
inferredcites →https://doi.org/10.1073/pnas.1916820117openalex-snapshot
A Cell Atlas of the Adult Drosophila Midgut
inferredcites →https://doi.org/10.1074/jbc.m111.220285openalex-snapshot
The Protein Dredd Is an Essential Component of the c-Jun N-terminal Kinase Pathway in the Drosophila Immune Response
inferredcites →https://doi.org/10.1074/jbc.m112.375881openalex-snapshot
Toll-like Receptor 4 Is Expressed on Intestinal Stem Cells and Regulates Their Proliferation and Apoptosis via the p53 Up-regulated Modulator of Apoptosis
inferredcites →https://doi.org/10.1074/jbc.m113.544841openalex-snapshot
The Caspase-8 Homolog Dredd Cleaves Imd and Relish but Is Not Inhibited by p35
inferredcites →https://doi.org/10.1084/jem.20120504openalex-snapshot
Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice
inferredcites →https://doi.org/10.1093/embo-reports/kvd072openalex-snapshot
Activation of the Drosophila NF‐κB factor Relish by rapid endoproteolytic cleavage
inferredcites →https://doi.org/10.1093/embo-reports/kvd073openalex-snapshot
The Drosophila caspase Dredd is required to resist Gram‐negative bacterial infection
inferredcites →https://doi.org/10.1098/rsob.180120openalex-snapshot
Tales from the crypt: intestinal niche signals in tissue renewal, plasticity and cancer
inferredcites →https://doi.org/10.1101/gad.1827009openalex-snapshot
Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila
inferredcites →https://doi.org/10.1111/febs.15910openalex-snapshot
Microbial recognition regulates intestinal epithelial growth in homeostasis and disease
inferredcites →https://doi.org/10.1111/j.1462-5822.2008.01267.xopenalex-snapshot
Genetic analysis ofDrosophila melanogastersusceptibility to intestinalVibrio choleraeinfection
inferredcites →https://doi.org/10.1111/j.1474-9726.2006.00251.xopenalex-snapshot
Trade‐offs between longevity and pathogen resistance in Drosophila melanogaster are mediated by NFκB signaling
inferredcites →https://doi.org/10.1126/science.1136606openalex-snapshot
Multipotent Drosophila Intestinal Stem Cells Specify Daughter Cell Fates by Differential Notch Signaling
inferredcites →https://doi.org/10.1126/science.1149357openalex-snapshot
Innate Immune Homeostasis by the Homeobox Gene Caudal and Commensal-Gut Mutualism in Drosophila
inferredcites →https://doi.org/10.1126/science.aab0988openalex-snapshot
Bidirectional Notch signaling regulates Drosophila intestinal stem cell multipotency
inferredcites →https://doi.org/10.1126/sciimmunol.aay8556openalex-snapshot
T cell–derived interferon-γ programs stem cell death in immune-mediated intestinal damage
inferredcites →https://doi.org/10.1126/stke.2202004pl6openalex-snapshot
Spatiotemporal Gene Expression Targeting with the TARGET and Gene-Switch Systems in Drosophila
inferredcites →https://doi.org/10.1128/mbio.00337-13openalex-snapshot
Mutations in the IMD Pathway and Mustard Counter Vibrio cholerae Suppression of Intestinal Stem Cell Division in Drosophila
inferredcites →https://doi.org/10.1128/mbio.00860-13openalex-snapshot
Frequent Replenishment Sustains the Beneficial Microbiome of Drosophila melanogaster
inferredcites →https://doi.org/10.1128/mbio.01117-13openalex-snapshot
Dual Role for Inflammasome Sensors NLRP1 and NLRP3 in Murine Resistance to Toxoplasma gondii
inferredcites →https://doi.org/10.1128/mbio.01117-14openalex-snapshot
Microbiota-Induced Changes in Drosophila melanogaster Host Gene Expression and Gut Morphology
inferredcites →https://doi.org/10.1128/mbio.01680-17openalex-snapshot
Lipopolysaccharide from Crypt-Specific Core Microbiota Modulates the Colonic Epithelial Proliferation-to-Differentiation Balance
inferredcites →https://doi.org/10.1128/mcb.00259-17openalex-snapshot
A Complex Relationship between Immunity and Metabolism in Drosophila Diet-Induced Insulin Resistance
inferredcites →https://doi.org/10.1128/mcb.24.1.172-185.2004openalex-snapshot
The Homeobox Gene Caudal Regulates Constitutive Local Expression of Antimicrobial Peptide Genes in Drosophila Epithelia
inferredcites →https://doi.org/10.1128/msystems.00162-16openalex-snapshot
Balance Trees Reveal Microbial Niche Differentiation
inferredcites →https://doi.org/10.1159/000475771openalex-snapshot
Oligopeptide Transporters of the SLC15 Family Are Dispensable for Peptidoglycan Sensing and Transport in Drosophila
inferredcites →https://doi.org/10.1172/jci62236openalex-snapshot
NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer
inferredcites →https://doi.org/10.1186/1741-7007-8-152openalex-snapshot
DrosophilaEGFR pathway coordinates stem cell proliferation and gut remodeling following infection
inferredcites →https://doi.org/10.1203/00006450-200104000-00023openalex-snapshot
Evidence for an Innate Immune Response in the Immature Human Intestine: Toll-Like Receptors on Fetal Enterocytes
inferredcites →https://doi.org/10.1242/dev.039404openalex-snapshot
Transcriptional control of stem cell maintenance in the Drosophila intestine
inferredcites →https://doi.org/10.1242/dev.065292openalex-snapshot
Distinct levels of Notch activity for commitment and terminal differentiation of stem cells in the adult fly intestine
inferredcites →https://doi.org/10.1242/dev.113357openalex-snapshot
Enteroendocrine cells are generated from stem cells through a distinct progenitor in the adult Drosophila posterior midgut
inferredcites →https://doi.org/10.1242/dev.114959openalex-snapshot
Generation of enteroendocrine cell diversity in midgut stem cell lineages
inferredcites →https://doi.org/10.1242/dev.155317openalex-snapshot
Microbiota promote secretory cell determination in the intestinal epithelium by modulating host Notch signaling
inferredcites →https://doi.org/10.1242/dmm.017400openalex-snapshot
How informative is the mouse for human gut microbiota research?
inferredcites →https://doi.org/10.1371/journal.pbio.2002054openalex-snapshot
Genomic dissection of conserved transcriptional regulation in intestinal epithelial cells
inferredcites →https://doi.org/10.1371/journal.pgen.1004117openalex-snapshot
Loss of Trabid, a New Negative Regulator of the Drosophila Immune-Deficiency Pathway at the Level of TAK1, Reduces Life Span
inferredcites →https://doi.org/10.1371/journal.pgen.1007931openalex-snapshot
Intestinal NF-κB and STAT signalling is important for uptake and clearance in a Drosophila-Herpetomonas interaction model
inferredcites →https://doi.org/10.1371/journal.pone.0094729openalex-snapshot
Drosophila Microbiota Modulates Host Metabolic Gene Expression via IMD/NF-κB Signaling
inferredcites →https://doi.org/10.1371/journal.ppat.0030173openalex-snapshot
A Model of Bacterial Intestinal Infections in Drosophila melanogaster
inferredcites →https://doi.org/10.1371/journal.ppat.1000694openalex-snapshot
Long-Range Activation of Systemic Immunity through Peptidoglycan Diffusion in Drosophila
inferredcites →https://doi.org/10.1371/journal.ppat.1006277openalex-snapshot
Drosophila as a model for homeostatic, antibacterial, and antiviral mechanisms in the gut
inferredcites →https://doi.org/10.15252/embr.201540188openalex-snapshot
Stem cell and progenitor fate in the mammalian intestine: Notch and lateral inhibition in homeostasis and disease
inferredcites →https://doi.org/10.1534/genetics.107.081968openalex-snapshot
Spatial and Temporal Control of Gene Expression in Drosophila Using the Inducible GeneSwitch GAL4 System. I. Screen for Larval Nervous System Drivers
inferredcites →https://doi.org/10.1534/genetics.116.190215openalex-snapshot
Interaction Between Familial Transmission and a Constitutively Active Immune System Shapes Gut Microbiota in Drosophila melanogaster
inferredcites →https://doi.org/10.1534/genetics.118.300224openalex-snapshot
Anatomy and Physiology of the Digestive Tract of Drosophila melanogaster
inferredcites →https://doi.org/10.1538/expanim.45.155openalex-snapshot
Histochemical, Lectin-Histochemical and Morphometrical Characteristics of Intestinal Goblet Cells of Germfree and Conventional Mice.
inferredcites →https://doi.org/10.3791/55024openalex-snapshot
The CApillary FEeder Assay Measures Food Intake in Drosophila melanogaster
inferredcites →https://doi.org/10.4049/jimmunol.1201022openalex-snapshot
Tissue- and Ligand-Specific Sensing of Gram-Negative Infection in Drosophila by PGRP-LC Isoforms and PGRP-LE
inferredcites →https://doi.org/10.4049/jimmunol.1303309openalex-snapshot
The Drosophila Imd Signaling Pathway
inferredcites →https://doi.org/10.4049/jimmunol.1600185openalex-snapshot
The Cytosolic Microbial Receptor Nod2 Regulates Small Intestinal Crypt Damage and Epithelial Regeneration following T Cell–Induced Enteropathy
inferredcites →https://doi.org/10.4049/jimmunol.1801632openalex-snapshot
The Immune Deficiency Pathway Regulates Metabolic Homeostasis in Drosophila
inferredcites →https://doi.org/10.4161/gmic.19896openalex-snapshot
Gut-associated microbes of Drosophila melanogaster

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1002/wdev.396openalex-snapshot
Single‐cell RNA sequencing in Drosophila: Technologies and applications
inferred← citeshttps://doi.org/10.1101/746305openalex-snapshot
Complex symbiont-pathogen interactions inhibit intestinal repair
inferred← citeshttps://doi.org/10.1111/febs.15910openalex-snapshot
Microbial recognition regulates intestinal epithelial growth in homeostasis and disease
inferred← citeshttps://doi.org/10.3389/fimmu.2019.03128openalex-snapshot
Host-Microbe-Pathogen Interactions: A Review of Vibrio cholerae Pathogenesis in Drosophila
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