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mRNA levels can be reduced by antisense oligonucleotides via no-go decay pathway
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/bies.10153openalex-snapshot
Non‐stop decay—a new mRNA surveillance pathway
inferredcites →https://doi.org/10.1002/wrna.17openalex-snapshot
No‐go decay: a quality control mechanism for RNA in translation
inferredcites →https://doi.org/10.1002/wrna.25openalex-snapshot
RNA decay modulates gene expression and controls its fidelity
inferredcites →https://doi.org/10.1002/wrna.40openalex-snapshot
Mechanisms of deadenylation‐dependent decay
inferredcites →https://doi.org/10.1007/978-1-4939-8651-4_4openalex-snapshot
Nusinersen in the Treatment of Spinal Muscular Atrophy
inferredcites →https://doi.org/10.1007/s40262-014-0224-4openalex-snapshot
Clinical and Preclinical Pharmacokinetics and Pharmacodynamics of Mipomersen (Kynamro®): A Second-Generation Antisense Oligonucleotide Inhibitor of Apolipoprotein B
inferredcites →https://doi.org/10.1016/j.ceb.2005.04.005openalex-snapshot
Nonsense-mediated mRNA decay: molecular insights and mechanistic variations across species
inferredcites →https://doi.org/10.1016/j.molcel.2004.06.031openalex-snapshot
Regulation of mRNA Decay
inferredcites →https://doi.org/10.1016/j.molcel.2017.08.019openalex-snapshot
Ribosome Collision Is Critical for Quality Control during No-Go Decay
inferredcites →https://doi.org/10.1016/j.plantsci.2018.07.008openalex-snapshot
The No-go decay system degrades plant mRNAs that contain a long A-stretch in the coding region
inferredcites →https://doi.org/10.1016/j.sbi.2005.05.006openalex-snapshot
Post-transcriptional gene silencing by siRNAs and miRNAs
inferredcites →https://doi.org/10.1016/j.tet.2004.06.009openalex-snapshot
Synthesis and acid catalyzed hydrolysis of B2,5 type conformationally constrained glucopyranosides: incorporation into a cellobiose analogue
inferredcites →https://doi.org/10.1016/j.tig.2016.08.007openalex-snapshot
A Universal Code for mRNA Stability?
inferredcites →https://doi.org/10.1016/j.ymthe.2017.06.002openalex-snapshot
RNase H1-Dependent Antisense Oligonucleotides Are Robustly Active in Directing RNA Cleavage in Both the Cytoplasm and the Nucleus
inferredcites →https://doi.org/10.1016/s0167-4781(99)00141-4openalex-snapshot
Importance of nucleotide sequence and chemical modifications of antisense oligonucleotides
inferredcites →https://doi.org/10.1016/s1359-6446(01)02123-7openalex-snapshot
Antisense Drug Technology: Principles, Strategies, and Applications
inferredcites →https://doi.org/10.1021/jo902560fopenalex-snapshot
Synthesis and Biophysical Evaluation of 2′,4′-Constrained 2′ O -Methoxyethyl and 2′,4′-Constrained 2′ O -Ethyl Nucleic Acid Analogues
inferredcites →https://doi.org/10.1038/nature04530openalex-snapshot
Endonucleolytic cleavage of eukaryotic mRNAs with stalls in translation elongation
inferredcites →https://doi.org/10.1038/nbt.3427openalex-snapshot
Antisense oligonucleotide–directed inhibition of nonsense-mediated mRNA decay
inferredcites →https://doi.org/10.1038/nbt.3589openalex-snapshot
Translation efficiency of mRNAs is increased by antisense oligonucleotides targeting upstream open reading frames
inferredcites →https://doi.org/10.1038/nbt.3779openalex-snapshot
Cellular uptake and trafficking of antisense oligonucleotides
inferredcites →https://doi.org/10.1038/nchembio.939openalex-snapshot
Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing
inferredcites →https://doi.org/10.1038/ncomms13521openalex-snapshot
Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution
inferredcites →https://doi.org/10.1038/nrm2104openalex-snapshot
The highways and byways of mRNA decay
inferredcites →https://doi.org/10.1038/nrm4063openalex-snapshot
Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes
inferredcites →https://doi.org/10.1038/nsmb.1922openalex-snapshot
Structure of the Dom34–Hbs1 complex and implications for no-go decay
inferredcites →https://doi.org/10.1038/nsmb.2057openalex-snapshot
Structure of the no-go mRNA decay complex Dom34–Hbs1 bound to a stalled 80S ribosome
inferredcites →https://doi.org/10.1038/srep29295openalex-snapshot
Mutations in the G-domain of Ski7 cause specific dysfunction in non-stop decay
inferredcites →https://doi.org/10.1042/bst0381615openalex-snapshot
Cutting the nonsense: the degradation of PTC-containing mRNAs
inferredcites →https://doi.org/10.1046/j.1432-1033.2003.03555.xopenalex-snapshot
Antisense technologies
inferredcites →https://doi.org/10.1073/pnas.0905780106openalex-snapshot
Triplet-repeat oligonucleotide-mediated reversal of RNA toxicity in myotonic dystrophy
inferredcites →https://doi.org/10.1074/jbc.271.24.14533openalex-snapshot
Nuclease Resistance and Antisense Activity of Modified Oligonucleotides Targeted to Ha-
inferredcites →https://doi.org/10.1074/jbc.m112.448977openalex-snapshot
The Hbs1-Dom34 Protein Complex Functions in Non-stop mRNA Decay in Mammalian Cells
inferredcites →https://doi.org/10.1089/nat.2015.0576openalex-snapshot
Development of a Method for Profiling Protein Interactions with LNA-Modified Antisense Oligonucleotides Using Protein Microarrays
inferredcites →https://doi.org/10.1089/oli.1.2000.10.117openalex-snapshot
Phosphorothioate Oligodeoxynucleotides: What Is Their Origin and What Is Unique About Them?
inferredcites →https://doi.org/10.1091/mbc.e09-01-0028openalex-snapshot
Analysis of Dom34 and Its Function in No-Go Decay
inferredcites →https://doi.org/10.1093/hmg/7.7.1083openalex-snapshot
Modification of splicing in the dystrophin gene in cultured Mdx muscle cells by antisense oligoribonucleotides
inferredcites →https://doi.org/10.1093/nar/19.5.1113openalex-snapshot
Inhibition of translation initiation by antisense oligonucleotides via an RNase-H independent mechanism
inferredcites →https://doi.org/10.1093/nar/25.22.4429openalex-snapshot
The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes
inferredcites →https://doi.org/10.1093/nar/29.6.1293openalex-snapshot
Fully modified 2' MOE oligonucleotides redirect polyadenylation
inferredcites →https://doi.org/10.1093/nar/gkq1121openalex-snapshot
Efficient and specific knockdown of small non-coding RNAs in mammalian cells and in mice
inferredcites →https://doi.org/10.1093/nar/gku1311openalex-snapshot
Small antisense oligonucleotides against G-quadruplexes: specific mRNA translational switches
inferredcites →https://doi.org/10.1093/nar/gku184openalex-snapshot
Nonsense-mediated decay as a terminating mechanism for antisense oligonucleotides
inferredcites →https://doi.org/10.1093/nar/gku484openalex-snapshot
TCP1 complex proteins interact with phosphorothioate oligonucleotides and can co-localize in oligonucleotide-induced nuclear bodies in mammalian cells
inferredcites →https://doi.org/10.1093/nar/gku579openalex-snapshot
Phosphorothioate oligonucleotides can displaceNEAT1RNA and form nuclear paraspeckle-like structures
inferredcites →https://doi.org/10.1093/nar/gkv143openalex-snapshot
Identification and characterization of intracellular proteins that bind oligonucleotides with phosphorothioate linkages
inferredcites →https://doi.org/10.1093/nar/gkv298openalex-snapshot
2′-Fluoro-modified phosphorothioate oligonucleotide can cause rapid degradation of P54nrb and PSF
inferredcites →https://doi.org/10.1093/nar/gkw065openalex-snapshot
RNA cleavage products generated by antisense oligonucleotides and siRNAs are processed by the RNA surveillance machinery
inferredcites →https://doi.org/10.1093/nar/gkw144openalex-snapshot
Hsp90 protein interacts with phosphorothioate oligonucleotides containing hydrophobic 2′-modifications and enhances antisense activity
inferredcites →https://doi.org/10.1093/nar/gkw595openalex-snapshot
Annexin A2 facilitates endocytic trafficking of antisense oligonucleotides
inferredcites →https://doi.org/10.1093/nar/gkx1174openalex-snapshot
Translation can affect the antisense activity of RNase H1-dependent oligonucleotides targeting mRNAs
inferredcites →https://doi.org/10.1093/nar/gkx632openalex-snapshot
Antisense oligonucleotides targeting translation inhibitory elements in 5′ UTRs can selectively increase protein levels
inferredcites →https://doi.org/10.1093/nar/gkx709openalex-snapshot
Nucleic acid binding proteins affect the subcellular distribution of phosphorothioate antisense oligonucleotides
inferredcites →https://doi.org/10.1093/nar/gky145openalex-snapshot
Cellular uptake mediated by epidermal growth factor receptor facilitates the intracellular activity of phosphorothioate-modified antisense oligonucleotides
inferredcites →https://doi.org/10.1093/nar/gky841openalex-snapshot
COPII vesicles can affect the activity of antisense oligonucleotides by facilitating the release of oligonucleotides from endocytic pathways
inferredcites →https://doi.org/10.1146/annurev-pharmtox-010716-104846openalex-snapshot
Pharmacology of Antisense Drugs
inferredcites →https://doi.org/10.1146/annurev.biochem.73.011303.074032openalex-snapshot
Eukaryotic mRNA Decapping
inferredcites →https://doi.org/10.1146/annurev.pharmtox.010909.105654openalex-snapshot
RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform
inferredcites →https://doi.org/10.1186/s13059-017-1386-9openalex-snapshot
Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for diseases caused by nonsense mutations
inferredcites →https://doi.org/10.1261/rna.059055.116openalex-snapshot
Transcriptome-wide identification of NMD-targeted human mRNAs reveals extensive redundancy between SMG6- and SMG7-mediated degradation pathways
inferredcites →https://doi.org/10.1371/journal.pbio.0050073openalex-snapshot
Enhancement of SMN2 Exon 7 Inclusion by Antisense Oligonucleotides Targeting the Exon
inferredcites →https://doi.org/10.1371/journal.pgen.1007818openalex-snapshot
Interactions between the mRNA and Rps3/uS3 at the entry tunnel of the ribosomal small subunit are important for no-go decay
inferredcites →https://doi.org/10.1371/journal.pone.0161930openalex-snapshot
Development of a Quantitative BRET Affinity Assay for Nucleic Acid-Protein Interactions
inferredcites →https://doi.org/10.3389/fgene.2018.00431openalex-snapshot
Lost in Translation: Ribosome-Associated mRNA and Protein Quality Controls
inferredcites →https://doi.org/10.4161/cc.4.3.1520openalex-snapshot
siRNA Induced Transcriptional Gene Silencing in Mammalian Cells
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Incoming claims: where this work appears in other papers’ reference lists and arguments.
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The powerful world of antisense oligonucleotides: From bench to bedside
inferred← citeshttps://doi.org/10.1007/s12035-021-02564-xopenalex-snapshot
LISTERIN E3 Ubiquitin Ligase and Ribosome-Associated Quality Control (RQC) Mechanism
inferred← citeshttps://doi.org/10.1007/s40259-025-00761-xopenalex-snapshot
Antisense Oligonucleotide Therapeutics Targeting Age-Related Diseases
inferred← citeshttps://doi.org/10.1016/b978-0-12-813955-4.00017-9openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/b978-0-443-19041-4.00039-xopenalex-snapshot
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TERT promoter mutations in gliomas: Molecular roles in tumorigenesis, metastasis, diagnosis, prognosis, therapeutic targeting, and drug resistance
inferred← citeshttps://doi.org/10.1016/j.bcp.2020.114196openalex-snapshot
Antisense drug discovery and development technology considered in a pharmacological context
inferred← citeshttps://doi.org/10.1016/j.biotechadv.2022.108047openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.gde.2025.102369openalex-snapshot
Transcriptional adaptation: where mRNA decay meets genetic compensation
inferred← citeshttps://doi.org/10.1016/j.jbc.2021.100416openalex-snapshot
Antisense technology: A review
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Inflammation-mediated diabetes-liver disease cross-organ crosstalk: From molecular mechanisms to precision therapeutic strategies
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The guide-RNA sequence dictates the slicing kinetics and conformational dynamics of the Argonaute silencing complex
inferred← citeshttps://doi.org/10.1016/j.omtn.2023.04.010openalex-snapshot
Block or degrade? Balancing on- and off-target effects of antisense strategies against transcripts with expanded triplet repeats in DM1
inferred← citeshttps://doi.org/10.1016/j.omtn.2025.102694openalex-snapshot
Antisense oligonucleotide-mediated upregulation of Jag1 ameliorates liver disease phenotypes in a mouse model of Alagille syndrome
inferred← citeshttps://doi.org/10.1016/j.virol.2024.110218openalex-snapshot
TMPRSS2-specific antisense oligonucleotides inhibit host cell entry of emerging viruses
inferred← citeshttps://doi.org/10.1021/acs.chemrev.4c00472openalex-snapshot
Technologies for Targeted RNA Degradation and Induced RNA Decay
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Exploration of Retron Elements for the Genetic Engineering of Acidithiobacillus ferrooxidans
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In-Cell Stability Prediction of RNA/DNA Hybrid Duplexes for Designing Oligonucleotides Aimed at Therapeutics
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Novel STAT3 oligonucleotide compounds suppress tumor growth and overcome the acquired resistance to sorafenib in hepatocellular carcinoma
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Likelihood of Nonspecific Activity of Gapmer Antisense Oligonucleotides Is Associated with Relative Hybridization Free Energy
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