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Response to a population bottleneck can be used to infer recessive selection

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/978-0-387-21822-9openalex-snapshot
Mathematical Population Genetics : I. Theoretical Introduction
inferredcites →https://doi.org/10.1016/j.tpb.2005.10.001openalex-snapshot
Prediction of effects of genetic drift on variance components under a general model of epistasis
inferredcites →https://doi.org/10.1017/s0021900200108368openalex-snapshot
Diffusion models in population genetics
inferredcites →https://doi.org/10.1038/nature06611openalex-snapshot
Proportionally more deleterious genetic variation in European than in African populations
inferredcites →https://doi.org/10.1038/nature07485openalex-snapshot
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome
inferredcites →https://doi.org/10.1038/nature10231openalex-snapshot
Inference of human population history from individual whole-genome sequences
inferredcites →https://doi.org/10.1038/nature11690openalex-snapshot
Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants
inferredcites →https://doi.org/10.1038/ng.2896openalex-snapshot
The deleterious mutation load is insensitive to recent population history
inferredcites →https://doi.org/10.1038/ng.937openalex-snapshot
Bayesian inference of ancient human demography from individual genome sequences
inferredcites →https://doi.org/10.1038/ng2116openalex-snapshot
Measurement of the human allele frequency spectrum demonstrates greater genetic drift in East Asians than in Europeans
inferredcites →https://doi.org/10.1038/ng812openalex-snapshot
Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis
inferredcites →https://doi.org/10.1038/nrg3425openalex-snapshot
Genomic signatures of selection at linked sites: unifying the disparity among species
inferredcites →https://doi.org/10.1038/sj.hdy.6883900openalex-snapshot
The effect of linkage disequilibrium and deviation from Hardy–Weinberg proportions on the changes in genetic variance with bottlenecking
inferredcites →https://doi.org/10.1046/j.1439-0388.2002.00356.xopenalex-snapshot
Genetics and Analysis of Quantitative Traits
inferredcites →https://doi.org/10.1073/pnas.1019276108openalex-snapshot
Demographic history and rare allele sharing among human populations
inferredcites →https://doi.org/10.1073/pnas.1213423109openalex-snapshot
Epistasis dominates the genetic architecture of Drosophila quantitative traits
inferredcites →https://doi.org/10.1073/pnas.60.2.517openalex-snapshot
The frequency distribution of lethal chromosomes in finite populations.
inferredcites →https://doi.org/10.1086/303312openalex-snapshot
The Effects of a Bottleneck on Inbreeding Depression and the Genetic Load
inferredcites →https://doi.org/10.1086/323659openalex-snapshot
The Importance of Genealogy in Determining Genetic Associations with Complex Traits
inferredcites →https://doi.org/10.1086/423146openalex-snapshot
A Population-Genetic Test of Founder Effects and Implications for Ashkenazi Jewish Diseases
inferredcites →https://doi.org/10.1093/genetics/114.4.1191openalex-snapshot
THE EFFECT OF AN EXPERIMENTAL BOTTLENECK UPON QUANTITATIVE GENETIC VARIATION IN THE HOUSEFLY
inferredcites →https://doi.org/10.1093/genetics/150.1.435openalex-snapshot
Bottleneck Effect on Genetic Variance: A Theoretical Investigation of the Role of Dominance
inferredcites →https://doi.org/10.1093/genetics/37.2.189openalex-snapshot
THE EFFECT OF INBREEDING ON THE VARIATION DUE TO RECESSIVE GENES
inferredcites →https://doi.org/10.1093/molbev/mst125openalex-snapshot
Inferring Demography from Runs of Homozygosity in Whole-Genome Sequence, with Correction for Sequence Errors
inferredcites →https://doi.org/10.1111/j.0014-3820.2003.tb00284.xopenalex-snapshot
THE ADDITIVE GENETIC VARIANCE AFTER BOTTLENECKS IS AFFECTED BY THE NUMBER OF LOCI INVOLVED IN EPISTATIC INTERACTIONS
inferredcites →https://doi.org/10.1111/j.0014-3820.2004.tb01591.xopenalex-snapshot
EFFECTS OF GENETIC DRIFT ON VARIANCE COMPONENTS UNDER A GENERAL MODEL OF EPISTASIS
inferredcites →https://doi.org/10.1111/j.0014-3820.2006.tb00521.xopenalex-snapshot
WILL POPULATION BOTTLENECKS AND MULTILOCUS EPISTASIS INCREASE ADDITIVE GENETIC VARIANCE?
inferredcites →https://doi.org/10.1111/j.1558-5646.1996.tb02345.xopenalex-snapshot
EPISTASIS AS A SOURCE OF INCREASED ADDITIVE GENETIC VARIANCE AT POPULATION BOTTLENECKS
inferredcites →https://doi.org/10.1111/mec.12524openalex-snapshot
On the accumulation of deleterious mutations during range expansions
inferredcites →https://doi.org/10.1126/science.1219240openalex-snapshot
Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes
inferredcites →https://doi.org/10.1371/journal.pgen.1000008openalex-snapshot
Data and Theory Point to Mainly Additive Genetic Variance for Complex Traits
inferredcites →https://doi.org/10.1371/journal.pgen.1003521openalex-snapshot
Inferring Demographic History from a Spectrum of Shared Haplotype Lengths
inferredcites →https://doi.org/10.1534/genetics.103.025874openalex-snapshot
Redistribution of Gene Frequency and Changes of Genetic Variation Following a Bottleneck in Population Size
inferredcites →https://doi.org/10.1534/genetics.112.149096openalex-snapshot
Estimating Variable Effective Population Sizes from Multiple Genomes: A Sequentially Markov Conditional Sampling Distribution Approach
inferredcites →https://doi.org/10.1534/genetics.113.153973openalex-snapshot
Population Growth Inflates the Per-Individual Number of Deleterious Mutations and Reduces Their Mean Effect

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1038/ng.3186openalex-snapshot
No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans
inferred← citeshttps://doi.org/10.1101/002865openalex-snapshot
No evidence that natural selection has been less effective at removing deleterious mutations in Europeans than in West Africans
inferred← citeshttps://doi.org/10.1101/015917openalex-snapshot
Selection and explosive growth may hamper the performance of rare variant association tests
inferred← citeshttps://doi.org/10.1101/022947openalex-snapshot
Purging of deleterious variants due to drift and founder effect in Italian populations with extended autozygosity
inferred← citeshttps://doi.org/10.1111/mec.13154openalex-snapshot
Expansion load: recessive mutations and the role of standing genetic variation
inferred← citeshttps://doi.org/10.3732/ajb.1400084openalex-snapshot
Useful insights from evolutionary biology for developing perennial grain crops1
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