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Why cancer cells have a more hyperpolarised mitochondrial membrane potential and emergent prospects for therapy

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/biof.31openalex-snapshot
The bioenergetics of cancer: Is glycolysis the main ATP supplier in all tumor cells?
inferredcites →https://doi.org/10.1002/cbic.201300115openalex-snapshot
A Prototypical Small‐Molecule Modulator Uncouples Mitochondria in Response to Endogenous Hydrogen Peroxide Production
inferredcites →https://doi.org/10.1002/jnr.22659openalex-snapshot
The “B Space” of mitochondrial phosphorylation
inferredcites →https://doi.org/10.1007/s00249-013-0898-9openalex-snapshot
Electrogenic proton transport across lipid bilayer membranes mediated by cationic derivatives of rhodamine 19: comparison with anionic protonophores
inferredcites →https://doi.org/10.1007/s10540-006-9018-8openalex-snapshot
Targeting Dinitrophenol to Mitochondria: Limitations to the Development of a Self-limiting Mitochondrial Protonophore
inferredcites →https://doi.org/10.1007/s10637-015-0221-yopenalex-snapshot
A phase I open-labeled, single-arm, dose-escalation, study of dichloroacetate (DCA) in patients with advanced solid tumors
inferredcites →https://doi.org/10.1007/s10863-005-8642-5openalex-snapshot
ANT2 Isoform Required for Cancer Cell Glycolysis
inferredcites →https://doi.org/10.1007/s13181-011-0162-6openalex-snapshot
2,4-Dinitrophenol (DNP): A Weight Loss Agent with Significant Acute Toxicity and Risk of Death
inferredcites →https://doi.org/10.1016/0006-291x(84)91453-0openalex-snapshot
Rhodamine 123 inhibits bioenergetic function in isolated rat liver mitochondria
inferredcites →https://doi.org/10.1016/0006-291x(90)90861-gopenalex-snapshot
A single amino acid substitution in lactate dehydrogenase improves the catalytic efficiency with an alternative coenzyme
inferredcites →https://doi.org/10.1016/j.bbabio.2007.05.010openalex-snapshot
Effects of lipophilic dications on planar bilayer phospholipid membrane and mitochondria
inferredcites →https://doi.org/10.1016/j.bbabio.2010.03.025openalex-snapshot
The pivotal roles of mitochondria in cancer: Warburg and beyond and encouraging prospects for effective therapies
inferredcites →https://doi.org/10.1016/j.bbabio.2010.08.010openalex-snapshot
The Warburg and Crabtree effects: On the origin of cancer cell energy metabolism and of yeast glucose repression
inferredcites →https://doi.org/10.1016/j.bbabio.2010.10.008openalex-snapshot
Adenine nucleotide translocase 2 is a key mitochondrial protein in cancer metabolism
inferredcites →https://doi.org/10.1016/j.bbadis.2009.08.008openalex-snapshot
Mitochondria as ATP consumers in cellular pathology
inferredcites →https://doi.org/10.1016/j.bbamem.2008.04.011openalex-snapshot
The ADP and ATP transport in mitochondria and its carrier
inferredcites →https://doi.org/10.1016/j.bbrc.2007.07.165openalex-snapshot
Mixed lineage kinase 3 connects reactive oxygen species to c-Jun NH2-terminal kinase-induced mitochondrial apoptosis in genipin-treated PC3 human prostate cancer cells
inferredcites →https://doi.org/10.1016/j.bcp.2005.07.025openalex-snapshot
Genipin-induced apoptosis in hepatoma cells is mediated by reactive oxygen species/c-Jun NH2-terminal kinase-dependent activation of mitochondrial pathway
inferredcites →https://doi.org/10.1016/j.biocel.2008.06.013openalex-snapshot
Energetic signalling in the control of mitochondrial F1F0 ATP synthase activity in health and disease
inferredcites →https://doi.org/10.1016/j.biocel.2013.06.023openalex-snapshot
Nigericin selectively targets cancer stem cells in nasopharyngeal carcinoma
inferredcites →https://doi.org/10.1016/j.bpj.2012.08.050openalex-snapshot
A Biophysical Model of the Mitochondrial ATP-Mg/Pi Carrier
inferredcites →https://doi.org/10.1016/j.bpj.2012.11.1689openalex-snapshot
Translocation of Glycolytic ATP into Mitochondria of Cancer Cells does not Utilize the Adenine Nucleotide Transporter
inferredcites →https://doi.org/10.1016/j.cbi.2014.01.015openalex-snapshot
Clusianone, a naturally occurring nemorosone regioisomer, uncouples rat liver mitochondria and induces HepG2 cell death
inferredcites →https://doi.org/10.1016/j.ccr.2006.04.023openalex-snapshot
Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
inferredcites →https://doi.org/10.1016/j.ccr.2006.05.012openalex-snapshot
Cancer's sweet tooth
inferredcites →https://doi.org/10.1016/j.ccr.2006.10.020openalex-snapshot
A Mitochondria-K+ Channel Axis Is Suppressed in Cancer and Its Normalization Promotes Apoptosis and Inhibits Cancer Growth
inferredcites →https://doi.org/10.1016/j.cell.2010.11.010openalex-snapshot
ATP Consumption Promotes Cancer Metabolism
inferredcites →https://doi.org/10.1016/j.cmet.2007.10.002openalex-snapshot
The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
inferredcites →https://doi.org/10.1016/j.febslet.2011.04.004openalex-snapshot
Mitochondrial consumption of cytosolic ATP: Not so fast
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2010.05.031openalex-snapshot
Uncoupling protein-2 knockdown mediates the cytotoxic effects of cisplatin
inferredcites →https://doi.org/10.1016/j.jphotobiol.2008.12.010openalex-snapshot
Two-photon autofluorescence dynamics imaging reveals sensitivity of intracellular NADH concentration and conformation to cell physiology at the single-cell level
inferredcites →https://doi.org/10.1016/j.mam.2012.05.006openalex-snapshot
The mitochondrial ADP/ATP carrier (SLC25 family): Pathological implications of its dysfunction
inferredcites →https://doi.org/10.1016/j.mehy.2014.05.001openalex-snapshot
A new model for mitochondrial membrane potential production and storage
inferredcites →https://doi.org/10.1016/j.mito.2009.12.143openalex-snapshot
Uncoupling protein-2 and cancer
inferredcites →https://doi.org/10.1016/j.mito.2010.10.008openalex-snapshot
The anti-cancer agent nemorosone is a new potent protonophoric mitochondrial uncoupler
inferredcites →https://doi.org/10.1016/j.mito.2014.09.002openalex-snapshot
ATP/ADP ratio, the missed connection between mitochondria and the Warburg effect
inferredcites →https://doi.org/10.1016/j.phymed.2011.10.008openalex-snapshot
Effects of (−) mammea A/BB isolated from Calophyllum brasiliense leaves and derivatives on mitochondrial membrane of Leishmania amazonensis
inferredcites →https://doi.org/10.1016/j.tiv.2007.12.005openalex-snapshot
2,4-Dinitrophenol induces G1 phase arrest and apoptosis in human pulmonary adenocarcinoma Calu-6 cells
inferredcites →https://doi.org/10.1016/j.yexmp.2010.08.006openalex-snapshot
Cancer metabolism: The Warburg effect today
inferredcites →https://doi.org/10.1016/s0014-5793(04)00242-xopenalex-snapshot
The role and structure of mitochondrial carriers
inferredcites →https://doi.org/10.1016/s0014-5793(04)00293-5openalex-snapshot
Adenine nucleotide translocase 3 (ANT3) overexpression induces apoptosis in cultured cells
inferredcites →https://doi.org/10.1016/s0021-9258(17)38802-6openalex-snapshot
Mitochondrial and plasma membrane potentials cause unusual accumulation and retention of rhodamine 123 by human breast adenocarcinoma-derived MCF-7 cells.
inferredcites →https://doi.org/10.1016/s0022-2836(05)80360-2openalex-snapshot
Basic Local Alignment Search Tool
inferredcites →https://doi.org/10.1016/s0026-895x(24)12222-5openalex-snapshot
Further Insight into Mechanism of Action of Clodronate: Inhibition of Mitochondrial ADP/ATP Translocase by a Nonhydrolyzable, Adenine-Containing Metabolite
inferredcites →https://doi.org/10.1016/s0169-409x(01)00125-9openalex-snapshot
Delocalized lipophilic cations selectively target the mitochondria of carcinoma cells
inferredcites →https://doi.org/10.1016/s0169-409x(01)00131-4openalex-snapshot
Cationic bolasomes with delocalized charge centers as mitochondria-specific DNA delivery systems
inferredcites →https://doi.org/10.1016/s0169-409x(99)00069-1openalex-snapshot
Drug delivery to mitochondria: the key to mitochondrial medicine
inferredcites →https://doi.org/10.1016/s0531-5565(00)00135-2openalex-snapshot
Uncoupling to survive? The role of mitochondrial inefficiency in ageing
inferredcites →https://doi.org/10.1016/s0939-6411(03)00046-8openalex-snapshot
Hyperforin a constituent of St John's wort (Hypericum perforatum L.) extract induces apoptosis by triggering activation of caspases and with hypericin synergistically exerts cytotoxicity towards human malignant cell lines
inferredcites →https://doi.org/10.1016/s0968-0004(00)89112-4openalex-snapshot
Biochemistry (4th edn)
inferredcites →https://doi.org/10.1016/s1535-6108(02)00082-xopenalex-snapshot
A novel mitochondriotoxic small molecule that selectively inhibits tumor cell growth
inferredcites →https://doi.org/10.1021/bi0261490openalex-snapshot
The Human Mitochondrial ADP/ATP Carriers: Kinetic Properties and Biogenesis of Wild-Type and Mutant Proteins in the YeastS. cerevisiae
inferredcites →https://doi.org/10.1021/cb400944yopenalex-snapshot
Mito-DCA: A Mitochondria Targeted Molecular Scaffold for Efficacious Delivery of Metabolic Modulator Dichloroacetate
inferredcites →https://doi.org/10.1021/jm0509039openalex-snapshot
Immuno-suppressive Effect of Blocking the CD28 Signaling Pathway in T-cells by an Active Component of Echinacea Found by a Novel Pharmaceutical Screening Method
inferredcites →https://doi.org/10.1021/jm500174vopenalex-snapshot
Antiproliferative and Uncoupling Effects of Delocalized, Lipophilic, Cationic Gallic Acid Derivatives on Cancer Cell Lines. Validation in Vivo in Singenic Mice
inferredcites →https://doi.org/10.1021/mp900032ropenalex-snapshot
Multiple Triphenylphosphonium Cations Shuttle a Hydrophilic Peptide into Mitochondria
inferredcites →https://doi.org/10.1021/np100501nopenalex-snapshot
Mammea E/BB, an Isoprenylated Dihydroxycoumarin Protonophore That Potently Uncouples Mitochondrial Electron Transport, Disrupts Hypoxic Signaling in Tumor Cells
inferredcites →https://doi.org/10.1021/np300711eopenalex-snapshot
Glycolysis Inhibitor Screening Identifies the Bis-geranylacylphloroglucinol Protonophore Moronone from Moronobea coccinea
inferredcites →https://doi.org/10.1023/a:1008336904585openalex-snapshot
Phase I trial of the selective mitochondrial toxin MKT 077 in chemo-resistant solid tumours
inferredcites →https://doi.org/10.1038/35048073openalex-snapshot
The mitochondrion in apoptosis: how Pandora's box opens
inferredcites →https://doi.org/10.1038/415096aopenalex-snapshot
Superoxide activates mitochondrial uncoupling proteins
inferredcites →https://doi.org/10.1038/446474aopenalex-snapshot
Cancer patients opt for unapproved drug
inferredcites →https://doi.org/10.1038/emboj.2011.401openalex-snapshot
UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells
inferredcites →https://doi.org/10.1038/nature02056openalex-snapshot
Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside
inferredcites →https://doi.org/10.1038/nature02229openalex-snapshot
The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore
inferredcites →https://doi.org/10.1038/nature06734openalex-snapshot
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
inferredcites →https://doi.org/10.1038/nature06903openalex-snapshot
A novel route for ATP acquisition by the remnant mitochondria of Encephalitozoon cuniculi
inferredcites →https://doi.org/10.1038/nature08882openalex-snapshot
Zscan4 regulates telomere elongation and genomic stability in ES cells
inferredcites →https://doi.org/10.1038/nature13110openalex-snapshot
Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides
inferredcites →https://doi.org/10.1038/ncomms4936openalex-snapshot
Separating NADH and NADPH fluorescence in live cells and tissues using FLIM
inferredcites →https://doi.org/10.1038/ncpcardio0766openalex-snapshot
Mitochondrial oxidative metabolism is required for the cardiac differentiation of stem cells
inferredcites →https://doi.org/10.1038/nrc1478openalex-snapshot
Why do cancers have high aerobic glycolysis?
inferredcites →https://doi.org/10.1038/nrm2820openalex-snapshot
Sensors and regulators of intracellular pH
inferredcites →https://doi.org/10.1038/sj.bjp.0706628openalex-snapshot
A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen‐containing bisphosphonates
inferredcites →https://doi.org/10.1038/stemcells.2008.126openalex-snapshot
Two of a kind
inferredcites →https://doi.org/10.1038/stemcells.2008.62openalex-snapshot
Cancer and embryonic stem cells share genetic fingerprints
inferredcites →https://doi.org/10.1042/bj20050890openalex-snapshot
The basal proton conductance of mitochondria depends on adenine nucleotide translocase content
inferredcites →https://doi.org/10.1042/bj20060706openalex-snapshot
Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2 may be responsible for basal and fatty-acid-induced uncoupling respectively
inferredcites →https://doi.org/10.1042/bj20060919openalex-snapshot
Accumulation of lipophilic dications by mitochondria and cells
inferredcites →https://doi.org/10.1042/bj20070606openalex-snapshot
Mitochondrial uncouplers with an extraordinary dynamic range
inferredcites →https://doi.org/10.1046/j.1467-789x.2001.00043.xopenalex-snapshot
Mitochondrial uncoupling as a target for drug development for the treatment of obesity
inferredcites →https://doi.org/10.1073/pnas.0401346101openalex-snapshot
Restoration of an absent G 1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation
inferredcites →https://doi.org/10.1073/pnas.1011099107openalex-snapshot
Bioenergetic cost of making an adenosine triphosphate molecule in animal mitochondria
inferredcites →https://doi.org/10.1073/pnas.1103621108openalex-snapshot
Macromolecular organization of ATP synthase and complex I in whole mitochondria
inferredcites →https://doi.org/10.1073/pnas.1317400111openalex-snapshot
UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation
inferredcites →https://doi.org/10.1073/pnas.79.17.5292openalex-snapshot
Unusual retention of rhodamine 123 by mitochondria in muscle and carcinoma cells.
inferredcites →https://doi.org/10.1073/pnas.84.15.5444openalex-snapshot
Dequalinium, a topical antimicrobial agent, displays anticarcinoma activity based on selective mitochondrial accumulation.
inferredcites →https://doi.org/10.1074/jbc.m114.568204openalex-snapshot
The Chemical Uncoupler 2,4-Dinitrophenol (DNP) Protects against Diet-induced Obesity and Improves Energy Homeostasis in Mice at Thermoneutrality
inferredcites →https://doi.org/10.1074/jbc.m510916200openalex-snapshot
Simultaneous Monitoring of Ionophore- and Inhibitor-mediated Plasma and Mitochondrial Membrane Potential Changes in Cultured Neurons
inferredcites →https://doi.org/10.1074/jbc.m511064200openalex-snapshot
Induction of Oxidative Metabolism by Mitochondrial Frataxin Inhibits Cancer Growth
inferredcites →https://doi.org/10.1074/jbc.m806903200openalex-snapshot
Nonmitochondrial ATP/ADP Transporters Accept Phosphate as Third Substrate
inferredcites →https://doi.org/10.1083/jcb.147.7.1493openalex-snapshot
Adenine Nucleotide Translocase-1, a Component of the Permeability Transition Pore, Can Dominantly Induce Apoptosis
inferredcites →https://doi.org/10.1089/ars.2014.5952openalex-snapshot
Molecular Strategies for Targeting Antioxidants to Mitochondria: Therapeutic Implications
inferredcites →https://doi.org/10.1093/abbs/gmq063openalex-snapshot
Mitochondrial F1Fo-ATP synthase translocates to cell surface in hepatocytes and has high activity in tumor-like acidic and hypoxic environment
inferredcites →https://doi.org/10.1093/annonc/mdu331.38openalex-snapshot
A Phase I Open-Labelled, Single-Arm, Dose-Escalation, Study of Dichloroacetate (Dca) in Patients with Advanced Solid Tumours
inferredcites →https://doi.org/10.1096/fj.09-149898openalex-snapshot
Forward operation of adenine nucleotide translocase during F 0 F 1 ‐ATPase reversal: critical role of matrix substrate‐level phosphorylation
inferredcites →https://doi.org/10.1096/fj.10-162222openalex-snapshot
Mitochondrial matrix pH controls oxidative phosphorylation and metabolism‐secretion coupling in INS‐1E clonal β cells
inferredcites →https://doi.org/10.1097/00005392-199909010-00090openalex-snapshot
CALCIUM IONOPHORE, IONOMYCIN INHIBITS GROWTH OF HUMAN BLADDER CANCER CELLS BOTH IN VITRO AND IN VIVO WITH ALTERATION OF BCL-2 AND BAX EXPRESSION LEVELS
inferredcites →https://doi.org/10.1097/nen.0b013e3181b40217openalex-snapshot
Peripheral Neuropathy in Rats Exposed to Dichloroacetate
inferredcites →https://doi.org/10.1101/019307openalex-snapshot
NADH as a cancer medicine
inferredcites →https://doi.org/10.1111/bph.12638openalex-snapshot
The compound BTB 06584 is an IF 1‐dependent selective inhibitor of the mitochondrial F 1 F o‐ ATP ase
inferredcites →https://doi.org/10.1111/j.1365-2958.2008.06300.xopenalex-snapshot
Yeast mitochondria import ATP through the calcium‐dependent ATP‐Mg/Pi carrier Sal1p, and are ATP consumers during aerobic growth in glucose
inferredcites →https://doi.org/10.1111/j.1432-1033.1977.tb11625.xopenalex-snapshot
The Adenine-Nucleotide Exchange in Submitochondrial (Sonic) Particles
inferredcites →https://doi.org/10.1111/j.1742-4658.2010.07702.xopenalex-snapshot
The silencing of adenine nucleotide translocase isoform 1 induces oxidative stress and programmed cell death in ADF human glioblastoma cells
inferredcites →https://doi.org/10.1111/j.1755-5922.2008.00065.xopenalex-snapshot
Pharmacological Profile of the Selective Mitochondrial F 1 F 0 ATP Hydrolase Inhibitor BMS‐199264 in Myocardial Ischemia
inferredcites →https://doi.org/10.1126/science.1160809openalex-snapshot
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
inferredcites →https://doi.org/10.1126/science.123.3191.309openalex-snapshot
On the Origin of Cancer Cells
inferredcites →https://doi.org/10.1126/science.7146897openalex-snapshot
Rhodamine-123 Selectively Reduces Clonal Growth of Carcinoma Cells in Vitro
inferredcites →https://doi.org/10.1126/scitranslmed.3000677openalex-snapshot
Metabolic Modulation of Glioblastoma with Dichloroacetate
inferredcites →https://doi.org/10.1128/jb.00371-06openalex-snapshot
Study of the Five Rickettsia prowazekii Proteins Annotated as ATP/ADP Translocases (Tlc): Only Tlc1 Transports ATP/ADP, While Tlc4 and Tlc5 Transport Other Ribonucleotides
inferredcites →https://doi.org/10.1128/jb.00391-08openalex-snapshot
Lawsonia intracellularis Contains a Gene Encoding a Functional Rickettsia-Like ATP/ADP Translocase for Host Exploitation
inferredcites →https://doi.org/10.1128/jb.186.3.683-691.2004openalex-snapshot
ATP/ADP Translocases: a Common Feature of Obligate Intracellular Amoebal Symbionts Related to Chlamydiae and Rickettsiae
inferredcites →https://doi.org/10.1128/mmbr.00016-08openalex-snapshot
ATP Synthase and the Actions of Inhibitors Utilized To Study Its Roles in Human Health, Disease, and Other Scientific Areas
inferredcites →https://doi.org/10.1146/annurev-cellbio-092910-154237openalex-snapshot
Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
inferredcites →https://doi.org/10.1146/annurev.cb.04.110188.001103openalex-snapshot
Mitochondrial Membrane Potential in Living Cells
inferredcites →https://doi.org/10.1146/annurev.cellbio.4.1.155openalex-snapshot
Mitochondrial Membrane Potential In Living Cells
inferredcites →https://doi.org/10.1146/annurev.med.53.082901.104028openalex-snapshot
Positron Emission Tomography Scanning: Current and Future Applications
inferredcites →https://doi.org/10.1152/ajpheart.01019.2003openalex-snapshot
Excessive ATP hydrolysis in ischemic myocardium by mitochondrial F1F0-ATPase: effect of selective pharmacological inhibition of mitochondrial ATPase hydrolase activity
inferredcites →https://doi.org/10.1152/physiol.00005.2006openalex-snapshot
Molecular, Functional, and Pathological Aspects of the Mitochondrial ADP/ATP Carrier
inferredcites →https://doi.org/10.1155/2011/978583openalex-snapshot
Stable Differences in Intrinsic Mitochondrial Membrane Potential of Tumor Cell Subpopulations Reflect Phenotypic Heterogeneity
inferredcites →https://doi.org/10.1158/0008-5472.can-05-2444openalex-snapshot
The Intrinsic Mitochondrial Membrane Potential of Colonic Carcinoma Cells Is Linked to the Probability of Tumor Progression
inferredcites →https://doi.org/10.1158/0008-5472.can-05-2717openalex-snapshot
Growth Properties of Colonic Tumor Cells Are a Function of the Intrinsic Mitochondrial Membrane Potential
inferredcites →https://doi.org/10.1158/0008-5472.can-05-4407openalex-snapshot
Chemosensitization by Knockdown of Adenine Nucleotide Translocase-2
inferredcites →https://doi.org/10.1158/0008-5472.can-06-1501openalex-snapshot
Cancer's Molecular Sweet Tooth and the Warburg Effect
inferredcites →https://doi.org/10.1158/0008-5472.can-08-0053openalex-snapshot
The Mitochondrial Uncoupling Protein-2 Promotes Chemoresistance in Cancer Cells
inferredcites →https://doi.org/10.1158/0008-5472.can-08-0555openalex-snapshot
The Warburg Effect in Leukemia-Stroma Cocultures Is Mediated by Mitochondrial Uncoupling Associated with Uncoupling Protein 2 Activation
inferredcites →https://doi.org/10.1158/1535-7163.mct-06-0024openalex-snapshot
Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics
inferredcites →https://doi.org/10.1186/1471-2407-8-160openalex-snapshot
Over-expression of Adenine Nucleotide Translocase 1 (ANT1) Induces Apoptosis and Tumor Regression in vivo
inferredcites →https://doi.org/10.1186/1476-4598-12-152openalex-snapshot
Tumor glycolysis as a target for cancer therapy: progress and prospects
inferredcites →https://doi.org/10.1186/bcr1857openalex-snapshot
Suppression of adenine nucleotide translocase-2 by vector-based siRNA in human breast cancer cells induces apoptosis and inhibits tumor growth in vitro and in vivo
inferredcites →https://doi.org/10.1211/jpp.59.5.0013openalex-snapshot
Antiproliferative, cytotoxic and antitumour activity of coumarins isolated from Calophyllum brasiliense
inferredcites →https://doi.org/10.1242/jeb.203.1.41openalex-snapshot
Steady-State and Pre-Steady-State Kinetics of the Mitochondrial F1Fo ATPase: Is Atp Synthase a Reversible Molecular Machine?
inferredcites →https://doi.org/10.1248/bpb.29.817openalex-snapshot
Selective Cytotoxic Activity of Valinomycin against HT-29 Human Colon Carcinoma Cells via Down-Regulation of GRP78
inferredcites →https://doi.org/10.1289/ehp.9087213openalex-snapshot
Uncouplers of Oxidative Phosphorylation
inferredcites →https://doi.org/10.1371/journal.pbio.0050231openalex-snapshot
Enlightening Energy Parasitism by Analysis of an ATP/ADP Transporter from Chlamydiae
inferredcites →https://doi.org/10.1371/journal.pone.0013289openalex-snapshot
Genipin-Induced Inhibition of Uncoupling Protein-2 Sensitizes Drug-Resistant Cancer Cells to Cytotoxic Agents
inferredcites →https://doi.org/10.1371/journal.pone.0018433openalex-snapshot
Mild Mitochondrial Uncoupling and Calorie Restriction Increase Fasting eNOS, Akt and Mitochondrial Biogenesis
inferredcites →https://doi.org/10.1371/journal.pone.0024792openalex-snapshot
Cellular Model of Warburg Effect Identifies Tumor Promoting Function of UCP2 in Breast Cancer and Its Suppression by Genipin
inferredcites →https://doi.org/10.1371/journal.pone.0030714openalex-snapshot
UCP2 Inhibits ROS-Mediated Apoptosis in A549 under Hypoxic Conditions
inferredcites →https://doi.org/10.1371/journal.pone.0061902openalex-snapshot
Penetrating Cations Enhance Uncoupling Activity of Anionic Protonophores in Mitochondria
inferredcites →https://doi.org/10.1371/journal.pone.0109174openalex-snapshot
Inhibition Effect of a Custom Peptide on Lung Tumors
inferredcites →https://doi.org/10.14670/hh-22.85openalex-snapshot
Protection from oxidative stress by enhanced glycolysis; a possible mechanism of cellular immortalization.
inferredcites →https://doi.org/10.15252/embj.201490446openalex-snapshot
Pluripotent stem cell energy metabolism: an update
inferredcites →https://doi.org/10.2174/1381612819666131230124334openalex-snapshot
ATP Synthesis Revisited: New Avenues for the Management of Mitochondrial Diseases
inferredcites →https://doi.org/10.2174/187152008783961932openalex-snapshot
The Warburg Effect: Why and How Do Cancer Cells Activate Glycolysis in the Presence of Oxygen?
inferredcites →https://doi.org/10.3389/fphys.2013.00370openalex-snapshot
pH sensing and regulation in cancer
inferredcites →https://doi.org/10.3390/cancers2020567openalex-snapshot
Role of Uncoupling Proteins in Cancer
inferredcites →https://doi.org/10.3748/wjg.v21.i11.3232openalex-snapshot
Mitochondrial uncoupling protein 2 and pancreatic cancer: A new potential target therapy
inferredcites →https://doi.org/10.4236/jct.2014.53036openalex-snapshot
Want to Cure Cancer? Then Revisit the Past; “Warburg Was Correct”, Cancer Is a Metabolic Disease

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1002/adma.202209529openalex-snapshot
In Response to Precision Medicine: Current Subcellular Targeting Strategies for Cancer Therapy
inferred← citeshttps://doi.org/10.1002/glia.23905openalex-snapshot
Mitochondrial dynamics and bioenergetics regulated by netrin‐1 in oligodendrocytes
inferred← citeshttps://doi.org/10.1007/978-1-0716-2309-1_11openalex-snapshot
Mitochondrial Toxicity of Organic Arsenicals
inferred← citeshttps://doi.org/10.1007/s10337-023-04246-3openalex-snapshot
A New Reverse Phase High-Performance Liquid Chromatography (RP-HPLC) Method for Determination of Kinetin Riboside (Plant Hormone) in Dequalinium Chloride Based Self-assembled Vesicles: Development, Validation, and Force Degradation Study
inferred← citeshttps://doi.org/10.1007/s11426-019-9677-7openalex-snapshot
Aggregation-induced emission luminogen for specific identification of malignant tumour in vivo
inferred← citeshttps://doi.org/10.1007/s13596-025-00855-5openalex-snapshot
Oligomeric flavonoids from Cyperus rotundus tubers suppress growth, induce apoptosis, and boost antioxidant defense in multiple cancer cell lines
inferred← citeshttps://doi.org/10.1016/j.bbadis.2020.165808openalex-snapshot
Mitochondria-targeted drug delivery in cancers
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2021.121261openalex-snapshot
Immune-regulating bimetallic metal-organic framework nanoparticles designed for cancer immunotherapy
inferred← citeshttps://doi.org/10.1016/j.drudis.2022.103469openalex-snapshot
Mitochondrial-targeted nanoparticles: Delivery and therapeutic agents in cancer
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2021.03.036openalex-snapshot
Mitochondria-targeted prooxidant effects of betulinic acid conjugated with delocalized lipophilic cation F16
inferred← citeshttps://doi.org/10.1016/j.lfs.2021.119773openalex-snapshot
Nanotherapeutic approaches to target mitochondria in cancer
inferred← citeshttps://doi.org/10.1016/j.mito.2024.101951openalex-snapshot
Mitochondrial bioenergetics of breast cancer
inferred← citeshttps://doi.org/10.1016/j.molmet.2021.101222openalex-snapshot
Exploring the therapeutic potential of mitochondrial uncouplers in cancer
inferred← citeshttps://doi.org/10.1016/j.nantod.2024.102374openalex-snapshot
A molecularly tailored closed-loop tumor cell energy nanodepleter for cancer starvation therapy
inferred← citeshttps://doi.org/10.1016/j.plrev.2022.09.003openalex-snapshot
The distinguishing electrical properties of cancer cells
inferred← citeshttps://doi.org/10.1016/j.tiv.2020.104907openalex-snapshot
Oligomycin-induced proton uncoupling
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.2c01594openalex-snapshot
Anticancer Activity of Region B Capsaicin Analogs
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5c02076openalex-snapshot
Lipophilic Cations as Mitochondria-Targeting Moieties: Recent Progress and Design Principles for Medicinal Chemistry
inferred← citeshttps://doi.org/10.1038/s41419-020-03251-wopenalex-snapshot
SEMG1/2 augment energy metabolism of tumor cells
inferred← citeshttps://doi.org/10.1038/s41586-019-0993-xopenalex-snapshot
Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma
inferred← citeshttps://doi.org/10.1038/s41598-017-10949-zopenalex-snapshot
Oscillations of ultra-weak photon emission from cancer and non-cancer cells stressed by culture medium change and TNF-α
inferred← citeshttps://doi.org/10.1038/s41598-020-65450-xopenalex-snapshot
Nanoparticle delivery of a pH-sensitive prodrug of doxorubicin and a mitochondrial targeting VES-H8R8 synergistically kill multi-drug resistant breast cancer cells
inferred← citeshttps://doi.org/10.1038/s41598-021-95278-yopenalex-snapshot
Novel Tl(III) complexes containing pyridine-2,6-dicarboxylate derivatives with selective anticancer activity through inducing mitochondria-mediated apoptosis in A375 cells
inferred← citeshttps://doi.org/10.1038/s43587-026-01122-1openalex-snapshot
Peroxisomes orchestrate metabolic flexibility and longevity via an interorganelle cascade
inferred← citeshttps://doi.org/10.1038/s44324-025-00080-3openalex-snapshot
Mitochondrial uncoupling, energy substrate utilization, and brown adipose tissue as therapeutic targets in cancer
inferred← citeshttps://doi.org/10.1039/d3ma00629hopenalex-snapshot
Circumventing challenges in mitochondrial targeting for cancer treatment: leveraging nanoplatforms for effective solutions
inferred← citeshttps://doi.org/10.1039/d4sc05393aopenalex-snapshot
Photodynamic therapy photosensitizers and photoactivated chemotherapeutics exhibit distinct bioenergetic profiles to impact ATP metabolism
inferred← citeshttps://doi.org/10.1039/d5nr03935eopenalex-snapshot
Emerging nano-delivery systems for targeting mitochondria
inferred← citeshttps://doi.org/10.1093/neuonc/noad099openalex-snapshot
Upstream open reading frame-encoded MP31 disrupts the mitochondrial quality control process and inhibits tumorigenesis in glioblastoma
inferred← citeshttps://doi.org/10.1101/035113openalex-snapshot
Cancer cells have distinct electrical properties that predict a susceptibility to lipophilic anions; a new cancer drug paradigm
inferred← citeshttps://doi.org/10.1101/2021.10.28.466310openalex-snapshot
IF1 Protein Controls Aging Rate
inferred← citeshttps://doi.org/10.1101/2022.09.30.510273openalex-snapshot
Targeting plasma membrane and mitochondrial instability in breast cancer cells and breast epithelial to mesenchymal transition-model cells by adamantyl diaza-crown ether ZG613
inferred← citeshttps://doi.org/10.1101/2025.02.14.638340openalex-snapshot
Peroxisomal Dysfunction Drives Loss of Dynamic Nutrient Responses to Initiate Metabolic Inflexibility During Aging
inferred← citeshttps://doi.org/10.1111/jpi.12536openalex-snapshot
Melatonin‐mediated downregulation of ZNF746 suppresses bladder tumorigenesis mainly through inhibiting the AKT‐MMP‐9 signaling pathway
inferred← citeshttps://doi.org/10.1111/php.13928openalex-snapshot
Mitochondrial targeting improves the selectivity of singlet‐oxygen cleavable prodrugs in NMIBC treatment
inferred← citeshttps://doi.org/10.1111/php.70048openalex-snapshot
Photodynamic priming ( PDP ) targets platinum resistance from chronic perfluoroalkyl substances ( PFAS ) exposure in ovarian cancer cells
inferred← citeshttps://doi.org/10.1134/s1990747823040062openalex-snapshot
Membrane-Active Mitochondria-Targeted Antitumor Agents and Drug Delivery Systems
inferred← citeshttps://doi.org/10.1158/1940-6207.capr-20-0425openalex-snapshot
Mitochondria as a Novel Target for Cancer Chemoprevention: Emergence of Mitochondrial-targeting Agents
inferred← citeshttps://doi.org/10.11606/d.82.2019.tde-27022020-105427openalex-snapshot
Avaliação do efeito citostático e citotóxico na terapia combinada de antineoplásicos em linhagens de câncer de mama (MDA-MB-231), fígado (HepG2) E PRÓSTATA (PC-3 E DU 145)
inferred← citeshttps://doi.org/10.1177/09731296241291625openalex-snapshot
Antiproliferative and Apoptotic Potential of Chicoric Acid, a Major Phytoconstituent of Cichorium intybus , against Colon Cancer Cells: A Possible Inhibition of CDC25 Phosphatases
inferred← citeshttps://doi.org/10.1186/s11671-016-1819-5openalex-snapshot
Fullerene C60 Penetration into Leukemic Cells and Its Photoinduced Cytotoxic Effects
inferred← citeshttps://doi.org/10.1186/s12964-025-02127-wopenalex-snapshot
Targeting mitochondrial proteases CLPP and LONP1 via disruption of mitochondrial redox homeostasis induces proteotoxic stress and suppresses tumor progression
inferred← citeshttps://doi.org/10.1186/s40659-019-0224-9openalex-snapshot
Effects of glutamine deprivation on oxidative stress and cell survival in breast cell lines
inferred← citeshttps://doi.org/10.1530/rem-25-0003openalex-snapshot
Targeting the bioenergetics of a resistant tumor: clinical insights into OXPHOS inhibition for cancer therapy
inferred← citeshttps://doi.org/10.15407/bioorganica2023.01.032openalex-snapshot
New phosphorylated 5-(hydroxyalkylamino)-1,3-oxazoles as potential anticancer agents
inferred← citeshttps://doi.org/10.15407/ubj88.01.044openalex-snapshot
Modulation of cisplatin-induced reactive oxygen species production by fullerene C(60) in normal and transformed lymphoid cells
inferred← citeshttps://doi.org/10.2174/0109298673368188250613112621openalex-snapshot
Recent Advances in the Application of Mitochondria-targeted Fluorescent Probes
inferred← citeshttps://doi.org/10.2174/1389201021666200611113734openalex-snapshot
Dihydroorotate Dehydrogenase Inhibitors Promote Cell Cycle Arrest and Disrupt Mitochondria Bioenergetics in Ramos Cells
inferred← citeshttps://doi.org/10.31083/j.fbl2808180openalex-snapshot
The Role of Mitochondrial Dysfunction in Cytotoxic Effects of Solanum nigrum Water Extract on MCF-7 and MDA-MB-231 Breast Cancer Cells
inferred← citeshttps://doi.org/10.31857/s0233475523040060openalex-snapshot
Membrane-Active Mitochondria-Targeted Antitumor Agents and Drug Delivery Systems
inferred← citeshttps://doi.org/10.32657/10356/165654openalex-snapshot
Augumenting the anticancer properties of l-phenylalanine functionalized nanoscopic porous amino acid mimics (Nano-pPAAMs)
inferred← citeshttps://doi.org/10.3389/fonc.2018.00514openalex-snapshot
Enhanced Cytotoxic Activity of Mitochondrial Mechanical Effectors in Human Lung Carcinoma H520 Cells: Pharmaceutical Implications for Cancer Therapy
inferred← citeshttps://doi.org/10.3390/app9245318openalex-snapshot
Magnetic Fields Trump Oxygen in Controlling the Death of Erythro-Leukemia Cells
inferred← citeshttps://doi.org/10.3390/biom13071112openalex-snapshot
Weak Radiofrequency Field Effects on Chemical Parameters That Characterize Oxidative Stress in Human Fibrosarcoma and Fibroblast Cells
inferred← citeshttps://doi.org/10.3390/biomedicines13071539openalex-snapshot
Betulinic Acid ω-Triphenylphosphonium Alkyl Esters: Antiproliferative Activities and In Silico Pharmacokinetic Profiles
inferred← citeshttps://doi.org/10.3390/biomedicines9101453openalex-snapshot
Feasibility of Photodynamic Therapy for Glioblastoma with the Mitochondria-Targeted Photosensitizer Tetramethylrhodamine Methyl Ester (TMRM)
inferred← citeshttps://doi.org/10.3390/brainsci10020075openalex-snapshot
Using Light for Therapy of Glioblastoma Multiforme (GBM)
inferred← citeshttps://doi.org/10.3390/cancers15092564openalex-snapshot
Methods to Evaluate Changes in Mitochondrial Structure and Function in Cancer
inferred← citeshttps://doi.org/10.3390/clinbioenerg2020009openalex-snapshot
A Narrative Review of the Role of Mitochondria in Cancer: From Metabolic Reprogramming to Therapeutic Targeting
inferred← citeshttps://doi.org/10.3390/ijms22084164openalex-snapshot
A Walk in the Memory, from the First Functional Approach up to Its Regulatory Role of Mitochondrial Bioenergetic Flow in Health and Disease: Focus on the Adenine Nucleotide Translocator
inferred← citeshttps://doi.org/10.3390/md18080417openalex-snapshot
Antimicrobial Peptide TP4 Targets Mitochondrial Adenine Nucleotide Translocator 2
inferred← citeshttps://doi.org/10.3390/nu12030871openalex-snapshot
Queuine Micronutrient Deficiency Promotes Warburg Metabolism and Reversal of the Mitochondrial ATP Synthase in Hela Cells
inferred← citeshttps://doi.org/10.3390/pharmaceutics12070597openalex-snapshot
RETRACTED: The Enhanced Cytotoxic and Pro-Apoptotic Effects of Optimized Simvastatin-Loaded Emulsomes on MCF-7 Breast Cancer Cells
inferred← citeshttps://doi.org/10.3390/pharmaceutics12100956openalex-snapshot
The Encapsulation of Febuxostat into Emulsomes Strongly Enhances the Cytotoxic Potential of the Drug on HCT 116 Colon Cancer Cells
inferred← citeshttps://doi.org/10.3390/pharmaceutics14122657openalex-snapshot
Mitochondrial Dysfunction: Pathophysiology and Mitochondria-Targeted Drug Delivery Approaches
inferred← citeshttps://doi.org/10.5204/thesis.eprints.247163openalex-snapshot
The role of Banf1 in mechanisms of cellular ageing and cancer prognosis
inferred← citeshttps://doi.org/10.64898/2026.03.26.714399openalex-snapshot
Organotin(IV) Dithiocarbamate Compounds Targeting A549 Lung Cancer Cells via Mitochondria-Mediated Apoptosis
inferred← citeshttps://doi.org/10.70675/c8e381a2z8745z4ba5z92c5z245033e340aaopenalex-snapshot
Cationic polymers and N-heterocyclic carbene-metal complexes as anti-cancer stem cell chemotherapeutics
inferred← citeshttps://doi.org/10.7554/elife.99438openalex-snapshot
Mitochondrial protein carboxyl-terminal alanine-threonine tailing promotes human glioblastoma growth by regulating mitochondrial function
inferred← citeshttps://doi.org/10.7554/elife.99438.1openalex-snapshot
The mitochondrial stress-induced protein carboxyl-terminal alanine and threonine tailing (msiCAT-tailing) promotes glioblastoma tumorigenesis by modulating mitochondrial functions
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