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Passenger mutations in 2500 cancer genomes: Overall molecular functional impact and consequences

https://doi.org/10.1101/280446
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/j.ajhg.2010.11.011openalex-snapshot
GCTA: A Tool for Genome-wide Complex Trait Analysis
inferredcites →https://doi.org/10.1016/j.oraloncology.2012.09.007openalex-snapshot
MATH, a novel measure of intratumor genetic heterogeneity, is high in poor-outcome classes of head and neck squamous cell carcinoma
inferredcites →https://doi.org/10.1016/j.tig.2012.11.004openalex-snapshot
Human diseases through the lens of network biology
inferredcites →https://doi.org/10.1038/nature08185openalex-snapshot
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
inferredcites →https://doi.org/10.1038/nature12477openalex-snapshot
Signatures of mutational processes in human cancer
inferredcites →https://doi.org/10.1038/nature12912openalex-snapshot
Discovery and saturation analysis of cancer genes across 21 tumour types
inferredcites →https://doi.org/10.1038/nature15394openalex-snapshot
An integrated map of structural variation in 2,504 human genomes
inferredcites →https://doi.org/10.1038/nature22992openalex-snapshot
Recurrent and functional regulatory mutations in breast cancer
inferredcites →https://doi.org/10.1038/ng.2762openalex-snapshot
Emerging landscape of oncogenic signatures across human cancers
inferredcites →https://doi.org/10.1038/ng.2764openalex-snapshot
The Cancer Genome Atlas Pan-Cancer analysis project
inferredcites →https://doi.org/10.1038/ng.608openalex-snapshot
Common SNPs explain a large proportion of the heritability for human height
inferredcites →https://doi.org/10.1038/nrc3999openalex-snapshot
The mini-driver model of polygenic cancer evolution
inferredcites →https://doi.org/10.1038/nrg.2015.17openalex-snapshot
Role of non-coding sequence variants in cancer
inferredcites →https://doi.org/10.1038/nrg3729openalex-snapshot
Mechanisms underlying mutational signatures in human cancers
inferredcites →https://doi.org/10.1038/nrm2549openalex-snapshot
Transcription-coupled DNA repair: two decades of progress and surprises
inferredcites →https://doi.org/10.1056/nejmp1508811openalex-snapshot
The Path to Cancer — Three Strikes and You're Out
inferredcites →https://doi.org/10.1073/pnas.1213968110openalex-snapshot
Impact of deleterious passenger mutations on cancer progression
inferredcites →https://doi.org/10.1101/161562openalex-snapshot
The evolutionary history of 2,658 cancers
inferredcites →https://doi.org/10.1101/161638openalex-snapshot
Large-Scale Uniform Analysis of Cancer Whole Genomes in Multiple Computing Environments
inferredcites →https://doi.org/10.1101/162784openalex-snapshot
Pan-cancer analysis of whole genomes
inferredcites →https://doi.org/10.1101/181339openalex-snapshot
Patterns of structural variation in human cancer
inferredcites →https://doi.org/10.1101/183889openalex-snapshot
Genomic basis for RNA alterations revealed by whole-genome analyses of 27 cancer types
inferredcites →https://doi.org/10.1101/190330openalex-snapshot
The whole-genome panorama of cancer drivers
inferredcites →https://doi.org/10.1101/237313openalex-snapshot
Discovery and characterization of coding and non-coding driver mutations in more than 2,500 whole cancer genomes
inferredcites →https://doi.org/10.1186/preaccept-1739683221127290openalex-snapshot
FunSeq2: A framework for prioritizing noncoding regulatory variants in cancer

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1038/s41375-020-0919-5openalex-snapshot
Frequent mutations in the amino-terminal domain of BCL7A impair its tumor suppressor role in DLBCL
inferred← citeshttps://doi.org/10.1038/s41467-020-14407-9openalex-snapshot
Estimating growth patterns and driver effects in tumor evolution from individual samples
inferred← citeshttps://doi.org/10.1038/s41467-021-21081-yopenalex-snapshot
A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement
inferred← citeshttps://doi.org/10.1038/s41467-021-25172-8openalex-snapshot
Interacting evolutionary pressures drive mutation dynamics and health outcomes in aging blood
inferred← citeshttps://doi.org/10.1186/s12920-019-0525-4openalex-snapshot
Impact of cancer mutational signatures on transcription factor motifs in the human genome
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