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Genome-wide association study of plasma triglycerides, phospholipids and relation to cardio-metabolic risk factors
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/j.bbadis.2014.05.030openalex-snapshot
Genetics of the human metabolome, what is next?
inferredcites →https://doi.org/10.1016/j.cmet.2013.06.013openalex-snapshot
A Genome-wide Association Study of the Human Metabolome in a Community-Based Cohort
inferredcites →https://doi.org/10.1016/s0021-9258(17)42194-6openalex-snapshot
Neutral sphingomyelinase action stimulates signal transduction of tumor necrosis factor-alpha in the synthesis of cholesteryl esters in human fibroblasts.
inferredcites →https://doi.org/10.1038/ejhg.2013.118openalex-snapshot
The Genome of the Netherlands: design, and project goals
inferredcites →https://doi.org/10.1038/ejhg.2015.106openalex-snapshot
Reanalysis of mGWAS results and in vitro validation show that lactate dehydrogenase interacts with branched-chain amino acid metabolism
inferredcites →https://doi.org/10.1038/nature10405openalex-snapshot
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
inferredcites →https://doi.org/10.1038/nature14132openalex-snapshot
New genetic loci link adipose and insulin biology to body fat distribution
inferredcites →https://doi.org/10.1038/nature14177openalex-snapshot
Genetic studies of body mass index yield new insights for obesity biology
inferredcites →https://doi.org/10.1038/ncomms10494openalex-snapshot
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels
inferredcites →https://doi.org/10.1038/ncomms10495openalex-snapshot
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
inferredcites →https://doi.org/10.1038/ncomms11122openalex-snapshot
Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA
inferredcites →https://doi.org/10.1038/ncomms7065openalex-snapshot
Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels
inferredcites →https://doi.org/10.1038/ncomms8208openalex-snapshot
Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels
inferredcites →https://doi.org/10.1038/ng.2247openalex-snapshot
A genome-wide association meta-analysis identifies new childhood obesity loci
inferredcites →https://doi.org/10.1038/ng.2383openalex-snapshot
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
inferredcites →https://doi.org/10.1038/ng.2385openalex-snapshot
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
inferredcites →https://doi.org/10.1038/ng.2610openalex-snapshot
Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders
inferredcites →https://doi.org/10.1038/ng.2756openalex-snapshot
Systematic identification of trans eQTLs as putative drivers of known disease associations
inferredcites →https://doi.org/10.1038/ng.2795openalex-snapshot
Common variants associated with plasma triglycerides and risk for coronary artery disease
inferredcites →https://doi.org/10.1038/ng.2797openalex-snapshot
Discovery and refinement of loci associated with lipid levels
inferredcites →https://doi.org/10.1038/ng.2982openalex-snapshot
An atlas of genetic influences on human blood metabolites
inferredcites →https://doi.org/10.1038/ng.3021openalex-snapshot
Whole-genome sequence variation, population structure and demographic history of the Dutch population
inferredcites →https://doi.org/10.1038/ng.3396openalex-snapshot
A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease
inferredcites →https://doi.org/10.1038/ng.3404openalex-snapshot
Partitioning heritability by functional annotation using genome-wide association summary statistics
inferredcites →https://doi.org/10.1038/ng.3406openalex-snapshot
An atlas of genetic correlations across human diseases and traits
inferredcites →https://doi.org/10.1038/ng.3437openalex-snapshot
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
inferredcites →https://doi.org/10.1038/ng.521openalex-snapshot
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
inferredcites →https://doi.org/10.1038/ng.784openalex-snapshot
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
inferredcites →https://doi.org/10.1038/ng.920openalex-snapshot
Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque
inferredcites →https://doi.org/10.1038/sj.ejhg.5201508openalex-snapshot
Evidence of genetic enrichment for exceptional survival using a family approach: the Leiden Longevity Study
inferredcites →https://doi.org/10.1038/sj.hdy.6800717openalex-snapshot
Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix
inferredcites →https://doi.org/10.1074/jbc.271.31.18431openalex-snapshot
Zn2+-stimulated Sphingomyelinase Is Secreted by Many Cell Types and Is a Product of the Acid Sphingomyelinase Gene
inferredcites →https://doi.org/10.1074/jbc.273.7.4081openalex-snapshot
Human Vascular Endothelial Cells Are a Rich and Regulatable Source of Secretory Sphingomyelinase
inferredcites →https://doi.org/10.1093/bioinformatics/btq340openalex-snapshot
METAL: fast and efficient meta-analysis of genomewide association scans
inferredcites →https://doi.org/10.1093/hmg/ddn288openalex-snapshot
Practical aspects of imputation-driven meta-analysis of genome-wide association studies
inferredcites →https://doi.org/10.1172/jci118934openalex-snapshot
Rabbit aorta and human atherosclerotic lesions hydrolyze the sphingomyelin of retained low-density lipoprotein. Proposed role for arterial-wall sphingomyelinase in subendothelial retention and aggregation of atherogenic lipoproteins.
inferredcites →https://doi.org/10.1186/1471-2105-11-288openalex-snapshot
GWAMA: software for genome-wide association meta-analysis
inferredcites →https://doi.org/10.1186/1752-0509-5-21openalex-snapshot
Gaussian graphical modeling reconstructs pathway reactions from high-throughput metabolomics data
inferredcites →https://doi.org/10.1371/journal.pgen.1000672openalex-snapshot
Genetic Determinants of Circulating Sphingolipid Concentrations in European Populations
inferredcites →https://doi.org/10.1371/journal.pgen.1002490openalex-snapshot
Genome-Wide Association Study Identifies Novel Loci Associated with Circulating Phospho- and Sphingolipid Concentrations
inferredcites →https://doi.org/10.1371/journal.pgen.1002607openalex-snapshot
Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals
inferredcites →https://doi.org/10.1371/journal.pgen.1004235openalex-snapshot
A Central Role for GRB10 in Regulation of Islet Function in Man
inferredcites →https://doi.org/10.1371/journal.pgen.1004835openalex-snapshot
Insight in Genome-Wide Association of Metabolite Quantitative Traits by Exome Sequence Analyses
inferredcites →https://doi.org/10.1375/twin.13.3.231openalex-snapshot
The Netherlands Twin Register Biobank: A Resource for Genetic Epidemiological Studies
inferredcites →https://doi.org/10.2337/db10-0502openalex-snapshot
Common Variants at 10 Genomic Loci Influence Hemoglobin A1C Levels via Glycemic and Nonglycemic Pathways
inferredcites →https://doi.org/10.2337/db11-0415openalex-snapshot
Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
inferredcites →https://doi.org/10.3390/ijms14047716openalex-snapshot
Sphingomyelin in High-Density Lipoproteins: Structural Role and Biological Function
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1007/s00018-020-03715-4openalex-snapshot
Integrating lipidomics and genomics: emerging tools to understand cardiovascular diseases
inferred← citeshttps://doi.org/10.1007/s00394-026-04119-zopenalex-snapshot
Comparative analysis of postprandial changes in the lipidome of capillary plasma and dry blood spots of young women
inferred← citeshttps://doi.org/10.1038/s41467-019-13770-6openalex-snapshot
Heritability estimates for 361 blood metabolites across 40 genome-wide association studies
inferred← citeshttps://doi.org/10.1038/s41467-023-38800-2openalex-snapshot
Whole-Genome Sequencing Analysis of Human Metabolome in Multi-Ethnic Populations
inferred← citeshttps://doi.org/10.1038/s41467-023-42532-8openalex-snapshot
Genome-wide association analysis of plasma lipidome identifies 495 genetic associations
inferred← citeshttps://doi.org/10.1038/s41598-024-68522-4openalex-snapshot
Association of plant-based diet indexes with the metabolomic profile
inferred← citeshttps://doi.org/10.1053/j.gastro.2021.11.015openalex-snapshot
Integrative Analysis of the Inflammatory Bowel Disease Serum Metabolome Improves Our Understanding of Genetic Etiology and Points to Novel Putative Therapeutic Targets
inferred← citeshttps://doi.org/10.1101/2024.12.04.24318368openalex-snapshot
Genome-wide Association Study of Complex Lipid Species: Results from the Population-based Rhineland Study
inferred← citeshttps://doi.org/10.1101/661769openalex-snapshot
The genomic architecture of blood metabolites based on a decade of genome-wide analyses
inferred← citeshttps://doi.org/10.1194/jlr.ra119000594openalex-snapshot
Heritability of 596 lipid species and genetic correlation with cardiovascular traits in the Busselton Family Heart Study
inferred← citeshttps://doi.org/10.1371/journal.pbio.3003349openalex-snapshot
Alterations in ether lipid metabolism in obesity revealed by systems genomics of multi-omics datasets
inferred← citeshttps://doi.org/10.31677/2072-6724-2023-67-2-237-250openalex-snapshot
Interbreed differences in the cholesterol profile in cattle in Western Siberia
inferred← citeshttps://doi.org/10.3389/fendo.2020.00652openalex-snapshot
Sphingolipids in the Heart: From Cradle to Grave
inferred← citeshttps://doi.org/10.3389/fnut.2023.1282741openalex-snapshot
Distinct patterns of personalised dietary advice delivered by a metabotype framework similarly improve dietary quality and metabolic health parameters: secondary analysis of a randomised controlled trial
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