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Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Temporal Changes in Resting Heart Rate and Deaths From Ischemic Heart Disease
inferredcites →https://doi.org/10.1006/jmcc.1997.0460openalex-snapshot
Dexamethasone-induced Up-regulation of Adrenomedullin and Atrial Natriuretic Peptide Genes in Cultured Rat Ventricular Myocytes
inferredcites →https://doi.org/10.1007/s10147-006-0616-zopenalex-snapshot
The TIMP-1 gene transferred through adenovirus mediation shows a suppressive effect on peritoneal metastases from gastric cancer
inferredcites →https://doi.org/10.1007/s12265-010-9243-1openalex-snapshot
Electrophysiological Mechanisms of the Anti-arrhythmic Effects of Omega-3 Fatty Acids
inferredcites →https://doi.org/10.1016/0002-8703(91)90970-sopenalex-snapshot
Pulse rate, coronary heart disease, and death: The NHANES I Epidemiologic Follow-up Study
inferredcites →https://doi.org/10.1016/0006-2952(93)90283-3openalex-snapshot
Arachidonic acid-induced Ca2+ release from isolated sarcoplasmic reticulum
inferredcites →https://doi.org/10.1016/0091-7435(87)90087-9openalex-snapshot
Incidence and precursors of hypertension in young adults: The Framingham offspring study
inferredcites →https://doi.org/10.1016/0092-8674(90)90273-hopenalex-snapshot
A molecular basis for familial hypertrophic cardiomyopathy: An αβ cardiac myosin heavy chain hybrid gene
inferredcites →https://doi.org/10.1016/j.ahj.2010.08.001openalex-snapshot
PLN-encoded phospholamban mutation in a large cohort of hypertrophic cardiomyopathy cases: Summary of the literature and implications for genetic testing
inferredcites →https://doi.org/10.1016/j.ajhg.2011.10.013openalex-snapshot
Blood Pressure Loci Identified with a Gene-Centric Array
inferredcites →https://doi.org/10.1016/j.atherosclerosis.2008.10.009openalex-snapshot
Tissue Factor Pathway Inhibitor-2 gene methylation is associated with low expression in carotid atherosclerotic plaques
inferredcites →https://doi.org/10.1016/j.atherosclerosis.2009.04.024openalex-snapshot
Tissue factor pathway inhibitor, vascular risk factors and subclinical atherosclerosis: The Multi-Ethnic Study of Atherosclerosis
inferredcites →https://doi.org/10.1016/j.cbi.2010.01.042openalex-snapshot
Acetylcholinesterase: From 3D structure to function
inferredcites →https://doi.org/10.1016/j.febslet.2007.01.095openalex-snapshot
New insights into mitochondrial fusion
inferredcites →https://doi.org/10.1016/j.jacc.2003.05.004openalex-snapshot
NKX2.5mutations in patients with congenital heart disease
inferredcites →https://doi.org/10.1016/j.jvs.2005.02.020openalex-snapshot
Genetic analysis of polymorphisms in biologically relevant candidate genes in patients with abdominal aortic aneurysms
inferredcites →https://doi.org/10.1016/j.tcm.2003.09.006openalex-snapshot
Pacemaker Channels and Sinus Node Arrhythmia
inferredcites →https://doi.org/10.1016/j.yjmcc.2009.01.004openalex-snapshot
Titin-based mechanical signalling in normal and failing myocardium
inferredcites →https://doi.org/10.1016/j.yjmcc.2011.06.008openalex-snapshot
Effects of different small HSPB members on contractile dysfunction and structural changes in a Drosophila melanogaster model for Atrial Fibrillation
inferredcites →https://doi.org/10.1016/s0006-291x(03)00526-6openalex-snapshot
Mutation of the phospholamban promoter associated with hypertrophic cardiomyopathy
inferredcites →https://doi.org/10.1016/s0022-0736(98)80034-4openalex-snapshot
Heritability of ECG measurements in adult male twins
inferredcites →https://doi.org/10.1016/s0026-895x(24)12560-6openalex-snapshot
Expression of Multiple Subtypes of Muscarinic Receptors and Cellular Distribution in the Human Heart
inferredcites →https://doi.org/10.1016/s0092-8674(00)81436-1openalex-snapshot
Molecular Distinction and Angiogenic Interaction between Embryonic Arteries and Veins Revealed by ephrin-B2 and Its Receptor Eph-B4
inferredcites →https://doi.org/10.1016/s0140-6736(10)61259-7openalex-snapshot
Heart rate as a risk factor in chronic heart failure (SHIFT): the association between heart rate and outcomes in a randomised placebo-controlled trial
inferredcites →https://doi.org/10.1016/s1053-2498(02)00557-0openalex-snapshot
Increased expression of extracellular matrix regulators TIMP1 and MMP1 in deteriorating heart failure
inferredcites →https://doi.org/10.1016/s1097-2765(02)00488-4openalex-snapshot
EphrinB Phosphorylation and Reverse Signaling
inferredcites →https://doi.org/10.1038/nature05954openalex-snapshot
A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila
inferredcites →https://doi.org/10.1038/nature06007openalex-snapshot
Variants conferring risk of atrial fibrillation on chromosome 4q25
inferredcites →https://doi.org/10.1038/nature09629openalex-snapshot
A population-specific HTR2B stop codon predisposes to severe impulsivity
inferredcites →https://doi.org/10.1038/nature10405openalex-snapshot
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
inferredcites →https://doi.org/10.1038/nchembio732openalex-snapshot
High-throughput assay for small molecules that modulate zebrafish embryonic heart rate
inferredcites →https://doi.org/10.1038/ncomms1871openalex-snapshot
Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues
inferredcites →https://doi.org/10.1038/ng.2213openalex-snapshot
Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
inferredcites →https://doi.org/10.1038/ng.2261openalex-snapshot
Meta-analysis identifies six new susceptibility loci for atrial fibrillation
inferredcites →https://doi.org/10.1038/ng.269openalex-snapshot
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
inferredcites →https://doi.org/10.1038/ng.327openalex-snapshot
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
inferredcites →https://doi.org/10.1038/ng.357openalex-snapshot
A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits
inferredcites →https://doi.org/10.1038/ng.361openalex-snapshot
Genome-wide association study identifies eight loci associated with blood pressure
inferredcites →https://doi.org/10.1038/ng.362openalex-snapshot
Common variants at ten loci modulate the QT interval duration in the QTSCD Study
inferredcites →https://doi.org/10.1038/ng.364openalex-snapshot
Common variants at ten loci influence QT interval duration in the QTGEN Study
inferredcites →https://doi.org/10.1038/ng.384openalex-snapshot
Genome-wide association study of blood pressure and hypertension
inferredcites →https://doi.org/10.1038/ng.416openalex-snapshot
Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry
inferredcites →https://doi.org/10.1038/ng.417openalex-snapshot
A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke
inferredcites →https://doi.org/10.1038/ng.511openalex-snapshot
Several common variants modulate heart rate, PR interval and QRS duration
inferredcites →https://doi.org/10.1038/ng.516openalex-snapshot
Genetic variation in SCN10A influences cardiac conduction
inferredcites →https://doi.org/10.1038/ng.517openalex-snapshot
Genome-wide association study of PR interval
inferredcites →https://doi.org/10.1038/ng.537openalex-snapshot
Common variants in KCNN3 are associated with lone atrial fibrillation
inferredcites →https://doi.org/10.1038/ng.543openalex-snapshot
Multiple common variants for celiac disease influencing immune gene expression
inferredcites →https://doi.org/10.1038/ng.716openalex-snapshot
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction
inferredcites →https://doi.org/10.1038/ng.768openalex-snapshot
Discovery and genotyping of genome structural polymorphism by sequencing on a population scale
inferredcites →https://doi.org/10.1038/ng.781openalex-snapshot
A rare variant in MYH6 is associated with high risk of sick sinus syndrome
inferredcites →https://doi.org/10.1038/ng.784openalex-snapshot
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
inferredcites →https://doi.org/10.1038/ng.922openalex-snapshot
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure
inferredcites →https://doi.org/10.1038/ng1526openalex-snapshot
Mutation in myosin heavy chain 6 causes atrial septal defect
inferredcites →https://doi.org/10.1038/ng2088openalex-snapshot
A new multipoint method for genome-wide association studies by imputation of genotypes
inferredcites →https://doi.org/10.1038/ng815openalex-snapshot
Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy
inferredcites →https://doi.org/10.1054/jcaf.2002.129278openalex-snapshot
Titin: An endosarcomeric protein that modulates myocardial stiffness in DCM
inferredcites →https://doi.org/10.1056/nejm199601113340206openalex-snapshot
Cardiac Pacing
inferredcites →https://doi.org/10.1073/pnas.0510519103openalex-snapshot
A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy
inferredcites →https://doi.org/10.1073/pnas.0904744106openalex-snapshot
GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling
inferredcites →https://doi.org/10.1073/pnas.1010122108openalex-snapshot
Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4
inferredcites →https://doi.org/10.1073/pnas.110149597openalex-snapshot
Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways
inferredcites →https://doi.org/10.1073/pnas.2434235100openalex-snapshot
The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart
inferredcites →https://doi.org/10.1074/jbc.m107669200openalex-snapshot
Csx/Nkx2-5 Is Required for Homeostasis and Survival of Cardiac Myocytes in the Adult Heart
inferredcites →https://doi.org/10.1080/07420520902924939openalex-snapshot
Clock Genes Display Rhythmic Expression in Human Hearts
inferredcites →https://doi.org/10.1086/497345openalex-snapshot
Handling Marker-Marker Linkage Disequilibrium: Pedigree Analysis with Clustered Markers
inferredcites →https://doi.org/10.1086/519795openalex-snapshot
PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses
inferredcites →https://doi.org/10.1093/bioinformatics/btm108openalex-snapshot
GenABEL: an R library for genome-wide association analysis
inferredcites →https://doi.org/10.1093/bioinformatics/btn564openalex-snapshot
SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap
inferredcites →https://doi.org/10.1093/bioinformatics/btq340openalex-snapshot
METAL: fast and efficient meta-analysis of genomewide association scans
inferredcites →https://doi.org/10.1093/cvr/cvp181openalex-snapshot
Mitochondrial OPA1, apoptosis, and heart failure
inferredcites →https://doi.org/10.1093/hmg/ddi202openalex-snapshot
Functional dissection of sequence-specific NKX2-5 DNA binding domain mutations associated with human heart septation defects using a yeast-based system
inferredcites →https://doi.org/10.1093/hmg/ddl117openalex-snapshot
Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids
inferredcites →https://doi.org/10.1093/hmg/ddq303openalex-snapshot
Genome-wide association analysis identifies multiple loci related to resting heart rate
inferredcites →https://doi.org/10.1093/molehr/6.9.811openalex-snapshot
Adrenomedullin is an autocrine regulator of endothelial growth in human endometrium
inferredcites →https://doi.org/10.1093/oxfordjournals.aje.a113046openalex-snapshot
HEART RATE AS A PROGNOSTIC FACTOR FOR CORONARY HEART DISEASE AND MORTALITY: FINDINGS IN THREE CHICAGO EPIDEMIOLOGIC STUDIES
inferredcites →https://doi.org/10.1097/01.psy.0000278973.14218.6bopenalex-snapshot
Correction to De Geus et al. Bivariate Genetic Modeling of Cardiovascular Stress Reactivity: Does Stress Uncover Genetic Variance? (May 2007)
inferredcites →https://doi.org/10.1097/psy.0b013e318049cc2dopenalex-snapshot
Bivariate Genetic Modeling of Cardiovascular Stress Reactivity: Does Stress Uncover Genetic Variance?
inferredcites →https://doi.org/10.1101/gad.13.3.295openalex-snapshot
Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis
inferredcites →https://doi.org/10.1101/gr.772403openalex-snapshot
PANTHER: A Library of Protein Families and Subfamilies Indexed by Function
inferredcites →https://doi.org/10.1111/j.1540-8167.2007.01030.xopenalex-snapshot
Heritability of QT Interval: How Much Is Explained by Genes for Resting Heart Rate?
inferredcites →https://doi.org/10.1111/j.1582-4934.2004.tb00477.xopenalex-snapshot
Expression of phospholipase D isozymes in scar and viable tissue in congestive heart failure due to myocardial infarction
inferredcites →https://doi.org/10.1111/j.1582-4934.2008.00219.xopenalex-snapshot
Atrial extracellular matrix remodelling in patients with atrial fibrillation
inferredcites →https://doi.org/10.1113/jphysiol.2005.100776openalex-snapshot
Properties of ivabradine‐induced block of HCN1 and HCN4 pacemaker channels
inferredcites →https://doi.org/10.1126/science.1081578openalex-snapshot
Dilated Cardiomyopathy and Heart Failure Caused by a Mutation in Phospholamban
inferredcites →https://doi.org/10.1126/science.6484569openalex-snapshot
Retarding Effect of Lowered Heart Rate on Coronary Atherosclerosis
inferredcites →https://doi.org/10.1128/mcb.26.7.2511-2518.2006openalex-snapshot
Hydrops Fetalis, Cardiovascular Defects, and Embryonic Lethality in Mice Lacking the Calcitonin Receptor-Like Receptor Gene
inferredcites →https://doi.org/10.1146/annurev.genom.9.081307.164242openalex-snapshot
Genotype Imputation
inferredcites →https://doi.org/10.1152/ajpheart.00140.2011openalex-snapshot
Effect of dietary omega-3 fatty acids on the heart rate and the heart rate variability responses to myocardial ischemia or submaximal exercise
inferredcites →https://doi.org/10.1152/physiolgenomics.00206.2009openalex-snapshot
High-resolution cardiovascular function confirms functional orthology of myocardial contractility pathways in zebrafish
inferredcites →https://doi.org/10.1159/000435947openalex-snapshot
Heart Rate, Life Expectancy and the Cardiovascular System: Therapeutic Considerations
inferredcites →https://doi.org/10.1161/01.atv.0000254147.89321.cfopenalex-snapshot
Adenovirus-Mediated Expression of Tissue Factor Pathway Inhibitor-2 Inhibits Endothelial Cell Migration and Angiogenesis
inferredcites →https://doi.org/10.1161/01.atv.12.11.1245openalex-snapshot
Experimental atherosclerosis at the carotid bifurcation of the cynomolgus monkey. Localization, compensatory enlargement, and the sparing effect of lowered heart rate.
inferredcites →https://doi.org/10.1161/01.cir.0000105900.21445.3dopenalex-snapshot
Involvement of Tissue Factor Pathway Inhibitor in the Coronary Circulation of Patients With Acute Coronary Syndromes
inferredcites →https://doi.org/10.1161/01.cir.69.4.790openalex-snapshot
Autonomic mechanisms in ventricular fibrillation induced by myocardial ischemia during exercise in dogs with healed myocardial infarction. An experimental preparation for sudden cardiac death.
inferredcites →https://doi.org/10.1161/01.cir.95.5.1214openalex-snapshot
Potent and Long-Lasting Vasodilatory Effects of Adrenomedullin in Humans
inferredcites →https://doi.org/10.1161/01.res.0000152325.07495.5aopenalex-snapshot
Connexin 43 Downregulation and Dephosphorylation in Nonischemic Heart Failure Is Associated With Enhanced Colocalized Protein Phosphatase Type 2A
inferredcites →https://doi.org/10.1161/01.res.86.12.1193openalex-snapshot
Gap Junctions in Cardiovascular Disease
inferredcites →https://doi.org/10.1161/circresaha.107.167783openalex-snapshot
A Missense Mutation in the CHRM2 Gene Is Associated With Familial Dilated Cardiomyopathy
inferredcites →https://doi.org/10.1161/circresaha.108.171835openalex-snapshot
Perinatal Loss of Nkx2-5 Results in Rapid Conduction and Contraction Defects
inferredcites →https://doi.org/10.1161/circulationaha.104.507699openalex-snapshot
α-Myosin Heavy Chain
inferredcites →https://doi.org/10.1161/circulationaha.107.706887openalex-snapshot
Point Mutation in the HCN4 Cardiac Ion Channel Pore Affecting Synthesis, Trafficking, and Functional Expression Is Associated With Familial Asymptomatic Sinus Bradycardia
inferredcites →https://doi.org/10.1161/circulationaha.107.712984openalex-snapshot
Omega-3 Fatty Acids and Cardiac Arrhythmias: Prior Studies and Recommendations for Future Research
inferredcites →https://doi.org/10.1161/circulationaha.110.961227openalex-snapshot
Paradigm of Genetic Mosaicism and Lone Atrial Fibrillation
inferredcites →https://doi.org/10.1172/jci113627openalex-snapshot
Molecular cloning and characterization of human cardiac alpha- and beta-form myosin heavy chain complementary DNA clones. Regulation of expression during development and pressure overload in human atrium.
inferredcites →https://doi.org/10.1172/jci119776openalex-snapshot
Myosin heavy chain gene expression in human heart failure.
inferredcites →https://doi.org/10.1186/1471-2105-11-134openalex-snapshot
ProbABEL package for genome-wide association analysis of imputed data
inferredcites →https://doi.org/10.1186/1471-2199-9-41openalex-snapshot
Interaction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCK
inferredcites →https://doi.org/10.1186/1476-511x-9-22openalex-snapshot
Postnatal ontogenesis of clock genes in mouse suprachiasmatic nucleus and heart
inferredcites →https://doi.org/10.1186/1479-7364-3-4-371openalex-snapshot
Current software for genotype imputation
inferredcites →https://doi.org/10.1242/dev.059386openalex-snapshot
The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis
inferredcites →https://doi.org/10.1253/circj.66.561openalex-snapshot
Novel Point Mutation in the Cardiac Transcription Factor CSX/NKX2.5 Associated With Congenital Heart Disease.
inferredcites →https://doi.org/10.1253/circj.71.1755openalex-snapshot
Higher Heart Rate Predicts the Risk of Developing Hypertension in a Normotensive Screened Cohort
inferredcites →https://doi.org/10.1292/jvms.70.411openalex-snapshot
Transient Expression of Phospholipase D1 during Heart Development in Rats
inferredcites →https://doi.org/10.1371/journal.pgen.1000279openalex-snapshot
Practical Issues in Imputation-Based Association Mapping
inferredcites →https://doi.org/10.1371/journal.pgen.1000338openalex-snapshot
Genome-Wide Association Study of Plasma Polyunsaturated Fatty Acids in the InCHIANTI Study
inferredcites →https://doi.org/10.1371/journal.pgen.1001058openalex-snapshot
Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits
inferredcites →https://doi.org/10.1371/journal.pgen.1001177openalex-snapshot
Genome-Wide Association Study of Blood Pressure Extremes Identifies Variant near UMOD Associated with Hypertension
inferredcites →https://doi.org/10.1371/journal.pgen.1001300openalex-snapshot
Genome-Wide Association Study of Coronary Heart Disease and Its Risk Factors in 8,090 African Americans: The NHLBI CARe Project
inferredcites →https://doi.org/10.1371/journal.pgen.1002793openalex-snapshot
The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits
inferredcites →https://doi.org/10.1371/journal.pone.0005698openalex-snapshot
NKX2-5 Regulates the Expression of β-Catenin and GATA4 in Ventricular Myocytes
inferredcites →https://doi.org/10.1371/journal.pone.0010827openalex-snapshot
Analyses and Comparison of Imputation-Based Association Methods
inferredcites →https://doi.org/10.1371/journal.pone.0031193openalex-snapshot
Identification of New Genes Involved in Human Adipogenesis and Fat Storage
inferredcites →https://doi.org/10.1515/cclm.2008.091openalex-snapshot
Serum levels of the osteoprotegerin, receptor activator of nuclear factor κ-B ligand, metalloproteinase-1 (MMP-1) and tissue inhibitors of MMP-1 levels are increased in men 6 months after acute myocardial infarction

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1002/ajmg.a.37297openalex-snapshot
Exome analysis of a family with Wolff–Parkinson–White syndrome identifies a novel disease locus
inferred← citeshttps://doi.org/10.1002/ar.23911openalex-snapshot
Filamin‐A as a Balance between Erk/Smad Activities During Cardiac Valve Development
inferred← citeshttps://doi.org/10.1002/clc.22578openalex-snapshot
The Risk of Atrial Fibrillation With Ivabradine Treatment: A Meta‐analysis With Trial Sequential Analysis of More Than 40000 Patients
inferred← citeshttps://doi.org/10.1002/da.22966openalex-snapshot
The association of depression and anxiety with cardiac autonomic activity: The role of confounding effects of antidepressants
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Statistical methods with exhaustive search in the identification of gene–gene interactions for colorectal cancer
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β2‐Adrenergic Receptor Gene Affects the Heart Rate Response of β‐Blockers: Evidence From 3 Clinical Studies
inferred← citeshttps://doi.org/10.1002/joa3.12847openalex-snapshot
Genome and atrial fibrillation
inferred← citeshttps://doi.org/10.1007/978-1-4614-0965-6_10openalex-snapshot
The Genetic Determinants of Common Obesity-Susceptibility
inferred← citeshttps://doi.org/10.1007/978-3-030-45457-9_17openalex-snapshot
Hereditary Cardiac Conduction Diseases
inferred← citeshttps://doi.org/10.1007/978-3-319-44203-7_16openalex-snapshot
Hereditary Cardiac Conduction Diseases
inferred← citeshttps://doi.org/10.1007/978-3-319-52031-5_11openalex-snapshot
The Genetic Determinants of Common Obesity-Susceptibility
inferred← citeshttps://doi.org/10.1007/978-3-319-66114-8_15openalex-snapshot
Inherited Conduction Disease and Atrial Fibrillation
inferred← citeshttps://doi.org/10.1007/978-3-7091-1883-2_62openalex-snapshot
Human Genetics of Arrhythmias
inferred← citeshttps://doi.org/10.1007/978-981-13-1429-2_1openalex-snapshot
Genome-Wide Association Studies of Hypertension and Several Other Cardiovascular Diseases
inferred← citeshttps://doi.org/10.1007/s00018-016-2400-1openalex-snapshot
Development of the cardiac pacemaker
inferred← citeshttps://doi.org/10.1007/s00059-020-04913-3openalex-snapshot
Association of T66A polymorphism in CASQ2 with PR interval in a Chinese population
inferred← citeshttps://doi.org/10.1007/s00103-016-2323-xopenalex-snapshot
12 Jahre AFNET. Vom Forschungsnetzwerk zur Academic Research Organisation
inferred← citeshttps://doi.org/10.1007/s00125-022-05653-1openalex-snapshot
Separating the direct effects of traits on atherosclerotic cardiovascular disease from those mediated by type 2 diabetes
inferred← citeshttps://doi.org/10.1007/s00246-019-02166-4openalex-snapshot
Tbx3-Mediated Regulation of Cardiac Conduction System Development and Function: Potential Contributions of Alternative RNA Processing
inferred← citeshttps://doi.org/10.1007/s00395-015-0468-7openalex-snapshot
Loss of dihydrolipoyl succinyltransferase (DLST) leads to reduced resting heart rate in the zebrafish
inferred← citeshttps://doi.org/10.1007/s00395-016-0557-2openalex-snapshot
Coding and non-coding variants in the SHOX2 gene in patients with early-onset atrial fibrillation
inferred← citeshttps://doi.org/10.1007/s00439-022-02502-4openalex-snapshot
Identifying shared genetic factors underlying epilepsy and congenital heart disease in Europeans
inferred← citeshttps://doi.org/10.1007/s00439-024-02661-6openalex-snapshot
Genetic evidence for T-wave area from 12-lead electrocardiograms to monitor cardiovascular diseases in patients taking diabetes medications
inferred← citeshttps://doi.org/10.1007/s00439-024-02684-zopenalex-snapshot
Fine mapping of candidate effector genes for heart rate
inferred← citeshttps://doi.org/10.1007/s00592-019-01344-3openalex-snapshot
Association between resting heart rate and incident diabetes risk: a Mendelian randomization study
inferred← citeshttps://doi.org/10.1007/s10522-016-9665-5openalex-snapshot
Lifetime regular exercise affects the incident of different arrhythmias and improves organismal health in aging female Drosophila melanogaster
inferred← citeshttps://doi.org/10.1007/s10539-023-09904-2openalex-snapshot
Gradualism, natural selection, and the randomness of mutation–fisher, Kimura, and Orr, connecting the dots
inferred← citeshttps://doi.org/10.1007/s10654-013-9866-zopenalex-snapshot
The Rotterdam Study: 2014 objectives and design update
inferred← citeshttps://doi.org/10.1007/s10654-015-0082-xopenalex-snapshot
The Rotterdam Study: 2016 objectives and design update
inferred← citeshttps://doi.org/10.1007/s10654-017-0321-4openalex-snapshot
The Rotterdam Study: 2018 update on objectives, design and main results
inferred← citeshttps://doi.org/10.1007/s11033-021-06517-4openalex-snapshot
Genetic predictors of sick sinus syndrome
inferred← citeshttps://doi.org/10.1007/s11356-022-24542-zopenalex-snapshot
Toxicity assessment of hexafluoropropylene oxide-dimer acid on morphology, heart physiology, and gene expression during zebrafish (Danio rerio) development
inferred← citeshttps://doi.org/10.1007/s12020-017-1331-4openalex-snapshot
Circulating microRNA-1a is a biomarker of Graves’ disease patients with atrial fibrillation
inferred← citeshttps://doi.org/10.1007/s12192-017-0787-8openalex-snapshot
The growing world of small heat shock proteins: from structure to functions
inferred← citeshttps://doi.org/10.1007/s12551-018-0435-2openalex-snapshot
Genomic approaches for the elucidation of genes and gene networks underlying cardiovascular traits
inferred← citeshttps://doi.org/10.1016/b978-0-12-802002-9.00014-5openalex-snapshot
Complexity of Molecular Genetics in the Inherited Cardiac Arrhythmias
inferred← citeshttps://doi.org/10.1016/b978-0-12-822951-4.00004-7openalex-snapshot
Genomic basis of heart rate and rhythm generation
inferred← citeshttps://doi.org/10.1016/b978-0-443-13868-3.00040-5openalex-snapshot
Genetic methods to evaluate evidence for causal effect of coffee on health
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2015.11.014openalex-snapshot
Evo-Devo
inferred← citeshttps://doi.org/10.1016/j.ajhg.2013.10.012openalex-snapshot
Beyond GWASs: Illuminating the Dark Road from Association to Function
inferred← citeshttps://doi.org/10.1016/j.ajhg.2016.06.025openalex-snapshot
GNB5 Mutations Cause an Autosomal-Recessive Multisystem Syndrome with Sinus Bradycardia and Cognitive Disability
inferred← citeshttps://doi.org/10.1016/j.ajhg.2022.08.004openalex-snapshot
Identification and single-base gene-editing functional validation of a cis-EPO variant as a genetic predictor for EPO-increasing therapies
inferred← citeshttps://doi.org/10.1016/j.amjcard.2014.05.040openalex-snapshot
A Genome-Wide Association Study to Identify Genomic Modulators of Rate Control Therapy in Patients With Atrial Fibrillation
inferred← citeshttps://doi.org/10.1016/j.amjcard.2016.06.013openalex-snapshot
Association Between Heart Rate at Rest and Incident Atrial Fibrillation (from the Copenhagen Electrocardiographic Study)
inferred← citeshttps://doi.org/10.1016/j.amjcard.2018.01.048openalex-snapshot
Observational and Genetic Associations of Resting Heart Rate With Aortic Valve Calcium
inferred← citeshttps://doi.org/10.1016/j.bbadis.2014.04.025openalex-snapshot
Systems genetics: From GWAS to disease pathways
inferred← citeshttps://doi.org/10.1016/j.bone.2019.02.009openalex-snapshot
Using zebrafish to study skeletal genomics
inferred← citeshttps://doi.org/10.1016/j.cellsig.2021.109947openalex-snapshot
Subtype-dependent regulation of Gβγ signalling
inferred← citeshttps://doi.org/10.1016/j.cjca.2023.07.011openalex-snapshot
Association Analyses of Predicted Loss-of-Function Variants Prioritized 15 Genes as Blood Pressure Regulators
inferred← citeshttps://doi.org/10.1016/j.cvdhj.2022.06.001openalex-snapshot
Deep learning on resting electrocardiogram to identify impaired heart rate recovery
inferred← citeshttps://doi.org/10.1016/j.devcel.2020.11.020openalex-snapshot
Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease
inferred← citeshttps://doi.org/10.1016/j.ebiom.2022.104288openalex-snapshot
Genetic determinants of cardiometabolic and pulmonary phenotypes and obstructive sleep apnoea in HCHS/SOL
inferred← citeshttps://doi.org/10.1016/j.expneurol.2015.03.016openalex-snapshot
Drosophila and experimental neurology in the post-genomic era
inferred← citeshttps://doi.org/10.1016/j.forsciint.2019.109944openalex-snapshot
Identifying blood-specific age-related DNA methylation markers on the Illumina MethylationEPIC® BeadChip
inferred← citeshttps://doi.org/10.1016/j.gene.2014.03.045openalex-snapshot
Insight into genetic determinants of resting heart rate
inferred← citeshttps://doi.org/10.1016/j.gene.2025.149269openalex-snapshot
The role of genetic polymorphisms in KCNN2 in cardiovascular complications in patients with renal failure
inferred← citeshttps://doi.org/10.1016/j.hlc.2019.06.726openalex-snapshot
Impact of Oxidative Stress on Long-Term Heart Rate Variability: Linear Versus Non-Linear Heart Rate Dynamics
inferred← citeshttps://doi.org/10.1016/j.hrcr.2020.03.003openalex-snapshot
The missense variant p.(Gly482Arg) in HCN4 is responsible for fetal tachy-bradycardia syndrome
inferred← citeshttps://doi.org/10.1016/j.hrthm.2017.06.018openalex-snapshot
Genome-wide association study of heart rate and its variability in Hispanic/Latino cohorts
inferred← citeshttps://doi.org/10.1016/j.hrthm.2018.10.036openalex-snapshot
2018 ACC/AHA/HRS guideline on the evaluation and management of patients with bradycardia and cardiac conduction delay: Executive summary
inferred← citeshttps://doi.org/10.1016/j.hrthm.2018.10.037openalex-snapshot
2018 ACC/AHA/HRS guideline on the evaluation and management of patients with bradycardia and cardiac conduction delay
inferred← citeshttps://doi.org/10.1016/j.hrthm.2022.08.024openalex-snapshot
GJA1 gene polymorphism is a genetic predictor of recurrence after pulmonary vein isolation in patients with paroxysmal atrial fibrillation
inferred← citeshttps://doi.org/10.1016/j.hrthm.2022.09.005openalex-snapshot
“Can we ablate your atrial fibrillation? Let’s check your bloodwork.” Genetic profiling and its role in ablation for atrial fibrillation
inferred← citeshttps://doi.org/10.1016/j.hrthm.2024.02.050openalex-snapshot
Symptomatic bradyarrhythmias in the athlete—Underlying mechanisms and treatments
inferred← citeshttps://doi.org/10.1016/j.ijcard.2015.01.048openalex-snapshot
CASP3 genetic variants and susceptibility to atrial fibrillation in Chinese Han population
inferred← citeshttps://doi.org/10.1016/j.ijcard.2015.11.127openalex-snapshot
Genome-wide rare copy number variations contribute to genetic risk for transposition of the great arteries
inferred← citeshttps://doi.org/10.1016/j.ijcha.2015.03.001openalex-snapshot
Cumulative effects of common genetic variants on risk of sudden cardiac death
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.113520openalex-snapshot
Use of mendelian randomization to assess the causal associations of circulating plasma proteins with 12-lead ECG parameters
inferred← citeshttps://doi.org/10.1016/j.jacadv.2025.102282openalex-snapshot
Ivabradine and Atrial Fibrillation Incidence
inferred← citeshttps://doi.org/10.1016/j.jacc.2013.09.025openalex-snapshot
Human Heart Rate
inferred← citeshttps://doi.org/10.1016/j.jacc.2014.05.045openalex-snapshot
HCN4 Mutations in Multiple Families With Bradycardia and Left Ventricular Noncompaction Cardiomyopathy
inferred← citeshttps://doi.org/10.1016/j.jacc.2017.09.005openalex-snapshot
A Missense Variant in PLEC Increases Risk of Atrial Fibrillation
inferred← citeshttps://doi.org/10.1016/j.jacc.2018.10.044openalex-snapshot
2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay
inferred← citeshttps://doi.org/10.1016/j.jacc.2019.03.519openalex-snapshot
Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals
inferred← citeshttps://doi.org/10.1016/j.jacc.2019.08.1055openalex-snapshot
Genome-Wide Assessment for Resting Heart Rate and Shared Genetics With Cardiometabolic Traits and Type 2 Diabetes
inferred← citeshttps://doi.org/10.1016/j.jacc.2022.07.014openalex-snapshot
The Athlete’s Heart—Challenges and Controversies
inferred← citeshttps://doi.org/10.1016/j.jacep.2020.10.009openalex-snapshot
Sex-Specific Ventricular Arrhythmias and Mortality in Cardiac Resynchronization Therapy Recipients
inferred← citeshttps://doi.org/10.1016/j.jelectrocard.2016.07.022openalex-snapshot
Genome-wide association studies and resting heart rate
inferred← citeshttps://doi.org/10.1016/j.pbiomolbio.2021.05.006openalex-snapshot
HCN4 current during human sinoatrial node-like action potentials
inferred← citeshttps://doi.org/10.1016/j.psychres.2024.115982openalex-snapshot
Genetic and polygenic investigation of heart rate variability to identify biomarkers associated with Anxiety disorders
inferred← citeshttps://doi.org/10.1016/j.tcm.2013.09.001openalex-snapshot
From GWAS to function: Genetic variation in sodium channel gene enhancer influences electrical patterning
inferred← citeshttps://doi.org/10.1016/j.tcm.2015.02.013openalex-snapshot
New approaches to establish genetic causality
inferred← citeshttps://doi.org/10.1016/j.tem.2015.10.004openalex-snapshot
GWAS as a Driver of Gene Discovery in Cardiometabolic Diseases
inferred← citeshttps://doi.org/10.1016/j.xgen.2026.101164openalex-snapshot
Discovery and characterization of gene-by-environment and epistatic genetic effects in a vertebrate model
inferred← citeshttps://doi.org/10.1016/j.xops.2023.100288openalex-snapshot
Genome-wide Association Studies of Retinal Vessel Tortuosity Identify Numerous Novel Loci Revealing Genes and Pathways Associated With Ocular and Cardiometabolic Diseases
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2015.10.028openalex-snapshot
Genetics meets epigenetics: Genetic variants that modulate noncoding RNA in cardiovascular diseases
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2017.05.009openalex-snapshot
Altered long non-coding RNA expression profile in rabbit atria with atrial fibrillation: TCONS_00075467 modulates atrial electrical remodeling by sponging miR-328 to regulate CACNA1C
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2018.05.005openalex-snapshot
Mutation of the Na+/K+-ATPase Atp1a1a.1 causes QT interval prolongation and bradycardia in zebrafish
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2023.04.004openalex-snapshot
The role of P21-activated kinase (Pak1) in sinus node function
inferred← citeshttps://doi.org/10.1017/cbo9781139519502.033openalex-snapshot
Research: Mediators and Moderators
inferred← citeshttps://doi.org/10.1017/s0007114524001971openalex-snapshot
Associations of the serum n-6 PUFA concentrations with exercise-induced myocardial ischaemia in middle-aged and older men
inferred← citeshttps://doi.org/10.1017/thg.2015.8openalex-snapshot
Genetic Contribution to the Variance of Blood Pressure and Heart Rate: A Systematic Review and Meta-Regression of Twin Studies
inferred← citeshttps://doi.org/10.1038/aps.2018.30openalex-snapshot
miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges
inferred← citeshttps://doi.org/10.1038/cr.2014.113openalex-snapshot
Baf250a orchestrates an epigenetic pathway to repress the Nkx2.5-directed contractile cardiomyocyte program in the sinoatrial node
inferred← citeshttps://doi.org/10.1038/ejhg.2017.50openalex-snapshot
Missing heritability: is the gap closing? An analysis of 32 complex traits in the Lifelines Cohort Study
inferred← citeshttps://doi.org/10.1038/ncomms15805openalex-snapshot
Genetic loci associated with heart rate variability and their effects on cardiac disease risk
inferred← citeshttps://doi.org/10.1038/ncomms8200openalex-snapshot
Translational regulation shapes the molecular landscape of complex disease phenotypes
inferred← citeshttps://doi.org/10.1038/ng.3014openalex-snapshot
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization
inferred← citeshttps://doi.org/10.1038/ng.3654openalex-snapshot
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
inferred← citeshttps://doi.org/10.1038/ng.3708openalex-snapshot
Identification of genomic loci associated with resting heart rate and shared genetic predictors with all-cause mortality
inferred← citeshttps://doi.org/10.1038/ng.3768openalex-snapshot
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
inferred← citeshttps://doi.org/10.1038/nmeth.2997openalex-snapshot
Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics
inferred← citeshttps://doi.org/10.1038/nprot.2013.092openalex-snapshot
Large-scale gene function analysis with the PANTHER classification system
inferred← citeshttps://doi.org/10.1038/nrcardio.2013.186openalex-snapshot
Genetics of sudden cardiac death caused by ventricular arrhythmias
inferred← citeshttps://doi.org/10.1038/s10038-020-0742-xopenalex-snapshot
IDDCA syndrome in a Chinese infant due to GNB5 biallelic mutations
inferred← citeshttps://doi.org/10.1038/s41398-020-0765-2openalex-snapshot
Genetic overlap between psychotic experiences in the community across age and with psychiatric disorders
inferred← citeshttps://doi.org/10.1038/s41431-018-0295-zopenalex-snapshot
Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits
inferred← citeshttps://doi.org/10.1038/s41467-018-03395-6openalex-snapshot
Genetic study links components of the autonomous nervous system to heart-rate profile during exercise
inferred← citeshttps://doi.org/10.1038/s41467-018-04148-1openalex-snapshot
Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system
inferred← citeshttps://doi.org/10.1038/s41467-018-04766-9openalex-snapshot
PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity
inferred← citeshttps://doi.org/10.1038/s41467-018-04931-0openalex-snapshot
Promoter interactome of human embryonic stem cell-derived cardiomyocytes connects GWAS regions to cardiac gene networks
inferred← citeshttps://doi.org/10.1038/s41467-018-06805-xopenalex-snapshot
Large-scale genome-wide enrichment analyses identify new trait-associated genes and pathways across 31 human phenotypes
inferred← citeshttps://doi.org/10.1038/s41467-018-07348-xopenalex-snapshot
Examining the current standards for genetic discovery and replication in the era of mega-biobanks
inferred← citeshttps://doi.org/10.1038/s41467-019-09014-2openalex-snapshot
DNA damage-induced PARP1 activation confers cardiomyocyte dysfunction through NAD+ depletion in experimental atrial fibrillation
inferred← citeshttps://doi.org/10.1038/s41467-019-09407-3openalex-snapshot
Phenotypes associated with genes encoding drug targets are predictive of clinical trial side effects
inferred← citeshttps://doi.org/10.1038/s41467-020-17329-8openalex-snapshot
Preservation of microvascular barrier function requires CD31 receptor-induced metabolic reprogramming
inferred← citeshttps://doi.org/10.1038/s41467-020-20578-2openalex-snapshot
Identification and analysis of splicing quantitative trait loci across multiple tissues in the human genome
inferred← citeshttps://doi.org/10.1038/s41467-022-28244-5openalex-snapshot
CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations
inferred← citeshttps://doi.org/10.1038/s41467-023-39521-2openalex-snapshot
Genetic insights into resting heart rate and its role in cardiovascular disease
inferred← citeshttps://doi.org/10.1038/s41467-024-54337-4openalex-snapshot
Single-cell transcriptome analysis reveals CD34 as a marker of human sinoatrial node pacemaker cardiomyocytes
inferred← citeshttps://doi.org/10.1038/s41467-024-55496-0openalex-snapshot
Rapid and accurate multi-phenotype imputation for millions of individuals
inferred← citeshttps://doi.org/10.1038/s41467-025-59425-7openalex-snapshot
Natural genetic variation quantitatively regulates heart rate and dimension
inferred← citeshttps://doi.org/10.1038/s41559-017-0167openalex-snapshot
Dietary adaptation of FADS genes in Europe varied across time and geography
inferred← citeshttps://doi.org/10.1038/s41569-018-0031-yopenalex-snapshot
Transcriptional regulation of the cardiac conduction system
inferred← citeshttps://doi.org/10.1038/s41569-025-01227-xopenalex-snapshot
The cardiac conduction system: development, function and therapeutic targets
inferred← citeshttps://doi.org/10.1038/s41586-021-03604-1openalex-snapshot
An atlas of gene regulatory elements in adult mouse cerebrum
inferred← citeshttps://doi.org/10.1038/s41588-018-0058-3openalex-snapshot
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
inferred← citeshttps://doi.org/10.1038/s41588-018-0133-9openalex-snapshot
Multi-ethnic genome-wide association study for atrial fibrillation
inferred← citeshttps://doi.org/10.1038/s41588-019-0499-3openalex-snapshot
Allele-specific NKX2-5 binding underlies multiple genetic associations with human electrocardiographic traits
inferred← citeshttps://doi.org/10.1038/s41588-022-01284-9openalex-snapshot
Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction
inferred← citeshttps://doi.org/10.1038/s41588-024-01978-2openalex-snapshot
The impact of common and rare genetic variants on bradyarrhythmia development
inferred← citeshttps://doi.org/10.1038/s41598-020-58563-wopenalex-snapshot
Automated high-throughput heartbeat quantification in medaka and zebrafish embryos under physiological conditions
inferred← citeshttps://doi.org/10.1038/s41598-020-68567-1openalex-snapshot
Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR/Cas9-based approach
inferred← citeshttps://doi.org/10.1038/s41598-021-82117-3openalex-snapshot
Minor allele of GJA1 gene polymorphism is associated with higher heart rate during atrial fibrillation
inferred← citeshttps://doi.org/10.1038/s41598-021-84135-7openalex-snapshot
A genome-wide association and polygenic risk score study on abnormal electrocardiogram in a Chinese population
inferred← citeshttps://doi.org/10.1038/s41598-021-93979-yopenalex-snapshot
A Mendelian randomization analysis of the relationship between cardioembolic risk factors and ischemic stroke
inferred← citeshttps://doi.org/10.1038/s42003-023-05376-yopenalex-snapshot
Phenotypic but not genetically predicted heart rate variability associated with all-cause mortality
inferred← citeshttps://doi.org/10.1038/s42003-024-06703-7openalex-snapshot
Dual color optogenetic tool enables heart arrest, bradycardic, and tachycardic pacing in Drosophila melanogaster
inferred← citeshttps://doi.org/10.1038/s44161-025-00692-4openalex-snapshot
Region-specific gene expression and sex inform about disease susceptibility in the aorta
inferred← citeshttps://doi.org/10.1038/s44325-024-00032-8openalex-snapshot
Atrial cardiomyopathy in endurance athletes
inferred← citeshttps://doi.org/10.1080/00365513.2019.1566567openalex-snapshot
Resting heart rate and relation to disease and longevity: past, present and future
inferred← citeshttps://doi.org/10.1080/15622975.2022.2043561openalex-snapshot
Associations of common genetic risk variants of the muscarinic acetylcholine receptor M2 with cardiac autonomic dysfunction in patients with schizophrenia
inferred← citeshttps://doi.org/10.1093/ajcn/nqab014openalex-snapshot
Cardiovascular symptoms affect the patterns of habitual coffee consumption
inferred← citeshttps://doi.org/10.1093/ajh/hpv082openalex-snapshot
Clock Genes Explain a Large Proportion of Phenotypic Variance in Systolic Blood Pressure and This Control Is Not Modified by Environmental Temperature
inferred← citeshttps://doi.org/10.1093/bfgp/elt029openalex-snapshot
Genomics of cardiac electrical function
inferred← citeshttps://doi.org/10.1093/bfgp/elt031openalex-snapshot
Gene regulatory elements of the cardiac conduction system
inferred← citeshttps://doi.org/10.1093/cvr/cvaa144openalex-snapshot
Genome-wide association studies of cardiac electrical phenotypes
inferred← citeshttps://doi.org/10.1093/cvr/cvab370openalex-snapshot
Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart
inferred← citeshttps://doi.org/10.1093/cvr/cvv006openalex-snapshot
Animal and in silico models for the study of sarcomeric cardiomyopathies
inferred← citeshttps://doi.org/10.1093/eurheartj/ehac049openalex-snapshot
Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapse
inferred← citeshttps://doi.org/10.1093/eurheartj/ehv173openalex-snapshot
Cardiovascular disease and sudden cardiac death: between genetics and genomics
inferred← citeshttps://doi.org/10.1093/eurheartj/ehx487openalex-snapshot
Big data from electronic health records for early and late translational cardiovascular research: challenges and potential
inferred← citeshttps://doi.org/10.1093/europace/eut348openalex-snapshot
Pacemaker activity of the human sinoatrial node: effects of HCN4 mutations on the hyperpolarization-activated current
inferred← citeshttps://doi.org/10.1093/europace/euw038openalex-snapshot
Quantitative analysis ofPKP2and neighbouring genes in a patient with arrhythmogenic right ventricular cardiomyopathy caused by heterozygousPKP2deletion
inferred← citeshttps://doi.org/10.1093/europace/eux061openalex-snapshot
Left bundle branch block: from cardiac mechanics to clinical and diagnostic challenges
inferred← citeshttps://doi.org/10.1093/function/zqac055openalex-snapshot
Slowing Heart Rate Protects Against Pathological Cardiac Hypertrophy
inferred← citeshttps://doi.org/10.1093/hmg/ddv106openalex-snapshot
Cardiac deficiency of single cytochrome oxidase assembly factor scox induces p53-dependent apoptosis in a Drosophila cardiomyopathy model
inferred← citeshttps://doi.org/10.1093/hmg/ddw058openalex-snapshot
Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram
inferred← citeshttps://doi.org/10.1093/hmg/ddx043openalex-snapshot
Conditional eQTL analysis reveals allelic heterogeneity of gene expression
inferred← citeshttps://doi.org/10.1093/hmg/ddx113openalex-snapshot
Discovery of novel heart rate-associated loci using the Exome Chip
inferred← citeshttps://doi.org/10.1093/hmg/ddz269openalex-snapshot
Impact of sex hormone-binding globulin on the human phenome
inferred← citeshttps://doi.org/10.1093/ije/dyt268openalex-snapshot
Cohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu
inferred← citeshttps://doi.org/10.1093/jb/mvy096openalex-snapshot
Genome analyses for the Tohoku Medical Megabank Project towards establishment of personalized healthcare
inferred← citeshttps://doi.org/10.1093/molbev/msy202openalex-snapshot
Detection of Shared Balancing Selection in the Absence of Trans-Species Polymorphism
inferred← citeshttps://doi.org/10.1093/nar/gkv1262openalex-snapshot
The anatomical distribution of genetic associations
inferred← citeshttps://doi.org/10.1093/nar/gkw1186openalex-snapshot
PATZ1 down-regulates FADS1 by binding to rs174557 and is opposed by SP1/SREBP1c
inferred← citeshttps://doi.org/10.1097/fjc.0000000000000559openalex-snapshot
Genomics of Cardiovascular Measures of Autonomic Tone
inferred← citeshttps://doi.org/10.1097/md.0000000000004312openalex-snapshot
KCNN2 polymorphisms and cardiac tachyarrhythmias
inferred← citeshttps://doi.org/10.1101/121012openalex-snapshot
Novel locus influencing retinal venular tortuosity is also associated with risk of coronary artery disease
inferred← citeshttps://doi.org/10.1101/170142openalex-snapshot
Flipping the odds of drug development success through human genomics
inferred← citeshttps://doi.org/10.1101/2021.04.19.21255650openalex-snapshot
Genetic determinants of interventricular septal anatomy and the risk of ventricular septal defects and hypertrophic cardiomyopathy
inferred← citeshttps://doi.org/10.1101/2021.09.06.21263189openalex-snapshot
Trans-ancestry genome-wide analysis of atrial fibrillation provides new insights into disease biology and enables polygenic prediction of cardioembolic risk
inferred← citeshttps://doi.org/10.1101/2022.02.27.22268990openalex-snapshot
Multitrait Genome-Wide Analysis in the UK Biobank Reveals Novel and Distinct Variants Influencing Cardiovascular Traits in Africans and Europeans
inferred← citeshttps://doi.org/10.1101/2025.01.10.25320367openalex-snapshot
Ivabradine and Atrial Fibrillation Incidence: A Nested Matching Study
inferred← citeshttps://doi.org/10.1101/2025.04.24.650462openalex-snapshot
Discovery and characterisation of gene by environment and epistatic genetic effects in a vertebrate model
inferred← citeshttps://doi.org/10.1101/2025.07.08.663711openalex-snapshot
Exploring cardiac phenotypes of Drosophila orthologues of human genes associated to Brugada Syndrome (BrS)
inferred← citeshttps://doi.org/10.1101/319509openalex-snapshot
Clustering of Type 2 Diabetes Genetic Loci by Multi-Trait Associations Identifies Disease Mechanisms and Subtypes
inferred← citeshttps://doi.org/10.1101/363457openalex-snapshot
GWAS of QRS Duration Identifies New Loci Specific to Hispanic/Latino Populations Swenson Hispanic/Latino QRS GWAS
inferred← citeshttps://doi.org/10.1101/621334openalex-snapshot
Genome-wide association study of plasma triglycerides, phospholipids and relation to cardio-metabolic risk factors
inferred← citeshttps://doi.org/10.1101/835603openalex-snapshot
Modeling human TBX5 haploinsufficiency predicts regulatory networks for congenital heart disease
inferred← citeshttps://doi.org/10.1101/cshperspect.a037408openalex-snapshot
Development of the Cardiac Conduction System
inferred← citeshttps://doi.org/10.1101/cshperspect.a039230openalex-snapshot
Human Genomics and Drug Development
inferred← citeshttps://doi.org/10.1111/eci.12892openalex-snapshot
Heart rate as a predictor of cardiovascular risk
inferred← citeshttps://doi.org/10.1111/jce.13788openalex-snapshot
Potential use of ivabradine for treatment of atrial fibrillation
inferred← citeshttps://doi.org/10.1111/joim.12373openalex-snapshot
Low resting heart rates are associated with new‐onset atrial fibrillation in patients with vascular disease: results of the ONTARGET / TRANSCEND studies
inferred← citeshttps://doi.org/10.1113/jp284241openalex-snapshot
Genome‐wide association studies: utility and limitations for research in physiology
inferred← citeshttps://doi.org/10.1126/sciadv.abf1444openalex-snapshot
Cardiac cell type–specific gene regulatory programs and disease risk association
inferred← citeshttps://doi.org/10.1126/scitranslmed.aad3744openalex-snapshot
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease
inferred← citeshttps://doi.org/10.1128/mcb.01156-14openalex-snapshot
Estrogen-Related Receptor α (ERRα) and ERRγ Are Essential Coordinators of Cardiac Metabolism and Function
inferred← citeshttps://doi.org/10.1136/bjsports-2015-095294openalex-snapshot
Exercise genomics—a paradigm shift is needed: a commentary
inferred← citeshttps://doi.org/10.1136/heartjnl-2014-305482openalex-snapshot
Atrial fibrillation associated with ivabradine treatment: meta-analysis of randomised controlled trials
inferred← citeshttps://doi.org/10.1136/jmedgenet-2016-104112openalex-snapshot
A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium
inferred← citeshttps://doi.org/10.1136/openhrt-2014-000187openalex-snapshot
Genetic variation at the human connexin 43 locus but not at the connexin 40 locus is associated with left bundle branch block
inferred← citeshttps://doi.org/10.1146/annurev-pharmtox-031120-115815openalex-snapshot
Pharmacologic Approach to Sinoatrial Node Dysfunction
inferred← citeshttps://doi.org/10.1152/ajpcell.00271.2016openalex-snapshot
Differential effects of inhibitory G protein isoforms on G protein-gated inwardly rectifying K+ currents in adult murine atria
inferred← citeshttps://doi.org/10.1152/physiolgenomics.00004.2015openalex-snapshot
Genome-wide association studies and contribution to cardiovascular physiology
inferred← citeshttps://doi.org/10.1152/physiolgenomics.00157.2020openalex-snapshot
The role of resistance to inhibitors of cholinesterase 8b in the control of heart rate
inferred← citeshttps://doi.org/10.1155/2020/3854630openalex-snapshot
Association of Maternal Diabetes Mellitus and Polymorphisms of theNKX2.5Gene in Children with Congenital Heart Disease: A Single Centre-Based Case-Control Study
inferred← citeshttps://doi.org/10.1159/000496150openalex-snapshot
Genome-Wide Association Studies of Hypertension and Several Other Cardiovascular Diseases
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