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A Phenome-wide Mendelian Randomisation study on genetically determined serum urate levels in UK Biobank cohort

https://doi.org/10.1101/630293
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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/s004390000243openalex-snapshot
Segregation analysis of serum uric acid in the NHLBI Family Heart Study
inferredcites →https://doi.org/10.1007/s11926-010-0094-1openalex-snapshot
Uric Acid and Hypertension: Cause or Effect?
inferredcites →https://doi.org/10.1016/j.rdc.2014.02.001openalex-snapshot
Gout and Crystal Arthropathies
inferredcites →https://doi.org/10.1016/s0140-6736(08)61343-4openalex-snapshot
Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study
inferredcites →https://doi.org/10.1038/nbt.2749openalex-snapshot
Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data
inferredcites →https://doi.org/10.1038/ng.106openalex-snapshot
SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout
inferredcites →https://doi.org/10.1038/ng.2500openalex-snapshot
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations
inferredcites →https://doi.org/10.1038/ng.3926openalex-snapshot
Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank
inferredcites →https://doi.org/10.1056/nejmra0800885openalex-snapshot
Uric Acid and Cardiovascular Risk
inferredcites →https://doi.org/10.1097/bor.0b013e32835d951eopenalex-snapshot
Metabolic syndrome, diabetes, and hyperuricemia
inferredcites →https://doi.org/10.1097/hjh.0000000000000701openalex-snapshot
Serum uric acid and the risk of cardiovascular and renal disease
inferredcites →https://doi.org/10.1097/mol.0000000000000155openalex-snapshot
Glucokinase regulatory protein
inferredcites →https://doi.org/10.1101/078972openalex-snapshot
MR-Base: a platform for systematic causal inference across the phenome using billions of genetic associations
inferredcites →https://doi.org/10.1101/173682openalex-snapshot
Automating Mendelian randomization through machine learning to construct a putative causal map of the human phenome
inferredcites →https://doi.org/10.1111/j.2517-6161.1995.tb02031.xopenalex-snapshot
Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
inferredcites →https://doi.org/10.1136/annrheumdis-2016-210602openalex-snapshot
2016 update of the EULAR recommendations for the management of early arthritis
inferredcites →https://doi.org/10.1136/annrheumdis-2017-212534openalex-snapshot
MR-PheWAS: exploring the causal effect of SUA level on multiple disease outcomes by using genetic instruments in UK Biobank
inferredcites →https://doi.org/10.1136/ard.51.3.375openalex-snapshot
Genetic control of the renal clearance of urate: a study of twins.
inferredcites →https://doi.org/10.1136/bmj.j2376openalex-snapshot
Serum uric acid levels and multiple health outcomes: umbrella review of evidence from observational studies, randomised controlled trials, and Mendelian randomisation studies
inferredcites →https://doi.org/10.1155/2014/852954openalex-snapshot
Review of Hyperuricemia as New Marker for Metabolic Syndrome
inferredcites →https://doi.org/10.1155/2015/127596openalex-snapshot
Relationship between Hyperuricemia and Lipid Profiles in US Adults
inferredcites →https://doi.org/10.1182/blood-2012-08-449272openalex-snapshot
Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function
inferredcites →https://doi.org/10.1371/journal.pgen.1000504openalex-snapshot
Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations
inferredcites →https://doi.org/10.1371/journal.pone.0114259openalex-snapshot
Hyperuricemia and Risk of Incident Hypertension: A Systematic Review and Meta-Analysis of Observational Studies
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