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MR-Base: a platform for systematic causal inference across the phenome using billions of genetic associations
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1001/jama.2016.13985openalex-snapshot
Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions
inferredcites →https://doi.org/10.1001/jama.2016.14568openalex-snapshot
Association Between Low-Density Lipoprotein Cholesterol–Lowering Genetic Variants and Risk of Type 2 Diabetes
inferredcites →https://doi.org/10.1001/jamacardio.2016.1884openalex-snapshot
Association of Lipid Fractions With Risks for Coronary Artery Disease and Diabetes
inferredcites →https://doi.org/10.1002/gepi.21758openalex-snapshot
Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data
inferredcites →https://doi.org/10.1002/gepi.21965openalex-snapshot
Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator
inferredcites →https://doi.org/10.1002/sim.3034openalex-snapshot
Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology
inferredcites →https://doi.org/10.1002/sim.6522openalex-snapshot
Detecting pleiotropy in Mendelian randomisation studies with summary data and a continuous outcome
inferredcites →https://doi.org/10.1016/j.ajhg.2011.11.029openalex-snapshot
Five Years of GWAS Discovery
inferredcites →https://doi.org/10.1016/j.ajhg.2014.03.004openalex-snapshot
Joint Analysis of Functional Genomic Data and Genome-wide Association Studies of 18 Human Traits
inferredcites →https://doi.org/10.1016/j.ajhg.2015.06.005openalex-snapshot
A Fast Method that Uses Polygenic Scores to Estimate the Variance Explained by Genome-wide Marker Panels and the Proportion of Variants Affecting a Trait
inferredcites →https://doi.org/10.1016/j.jacc.2012.09.017openalex-snapshot
Effect of Long-Term Exposure to Lower Low-Density Lipoprotein Cholesterol Beginning Early in Life on the Risk of Coronary Heart Disease
inferredcites →https://doi.org/10.1016/s0140-6736(03)13808-1openalex-snapshot
Primary biliary cirrhosis
inferredcites →https://doi.org/10.1016/s0140-6736(09)61965-6openalex-snapshot
Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials
inferredcites →https://doi.org/10.1016/s0140-6736(14)61183-1openalex-snapshot
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials
inferredcites →https://doi.org/10.1016/s0140-6736(15)61252-1openalex-snapshot
Antisense therapy targeting apolipoprotein(a): a randomised, double-blind, placebo-controlled phase 1 study
inferredcites →https://doi.org/10.1016/s0140-6736(16)31009-1openalex-snapshot
Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials
inferredcites →https://doi.org/10.1016/s0140-6736(16)31012-1openalex-snapshot
Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015
inferredcites →https://doi.org/10.1016/s0272-6386(96)90026-8openalex-snapshot
Lipoprotein(a) in renal disease
inferredcites →https://doi.org/10.1016/s2213-8587(16)30396-5openalex-snapshot
PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study
inferredcites →https://doi.org/10.1038/nature10405openalex-snapshot
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
inferredcites →https://doi.org/10.1038/ncomms11122openalex-snapshot
Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA
inferredcites →https://doi.org/10.1038/ncomms9019openalex-snapshot
International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways
inferredcites →https://doi.org/10.1038/ng.2797openalex-snapshot
Discovery and refinement of loci associated with lipid levels
inferredcites →https://doi.org/10.1038/ng.2897openalex-snapshot
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
inferredcites →https://doi.org/10.1038/ng.3314openalex-snapshot
The support of human genetic evidence for approved drug indications
inferredcites →https://doi.org/10.1038/ng.3396openalex-snapshot
A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease
inferredcites →https://doi.org/10.1038/ng.3406openalex-snapshot
An atlas of genetic correlations across human diseases and traits
inferredcites →https://doi.org/10.1038/nprot.2009.97openalex-snapshot
Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt
inferredcites →https://doi.org/10.1038/nrg.2016.142openalex-snapshot
Dissecting the genetics of complex traits using summary association statistics
inferredcites →https://doi.org/10.1038/srep18092openalex-snapshot
Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits
inferredcites →https://doi.org/10.1046/j.1523-1755.1999.00621.xopenalex-snapshot
Lipoprotein(a) and apolipoprotein(a) isoforms and proteinuria in patients with moderate renal failure
inferredcites →https://doi.org/10.1056/nejmoa0706728openalex-snapshot
Polymorphisms Associated with Cholesterol and Risk of Cardiovascular Events
inferredcites →https://doi.org/10.1056/nejmoa1400283openalex-snapshot
Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia
inferredcites →https://doi.org/10.1056/nejmoa1410489openalex-snapshot
Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes
inferredcites →https://doi.org/10.1056/nejmoa1500858openalex-snapshot
Efficacy and Safety of Evolocumab in Reducing Lipids and Cardiovascular Events
inferredcites →https://doi.org/10.1056/nejmoa1604304openalex-snapshot
Variation inPCSK9andHMGCRand Risk of Cardiovascular Disease and Diabetes
inferredcites →https://doi.org/10.1093/aje/kwr323openalex-snapshot
Credible Mendelian Randomization Studies: Approaches for Evaluating the Instrumental Variable Assumptions
inferredcites →https://doi.org/10.1093/aje/kwt084openalex-snapshot
Efficient Design for Mendelian Randomization Studies: Subsample and 2-Sample Instrumental Variable Estimators
inferredcites →https://doi.org/10.1093/bioinformatics/btu273openalex-snapshot
GRASP: analysis of genotype–phenotype results from 1390 genome-wide association studies and corresponding open access database
inferredcites →https://doi.org/10.1093/bioinformatics/btw373openalex-snapshot
PhenoScanner: a database of human genotype–phenotype associations
inferredcites →https://doi.org/10.1093/bioinformatics/btw613openalex-snapshot
LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis
inferredcites →https://doi.org/10.1093/database/bav028openalex-snapshot
DisGeNET: a discovery platform for the dynamical exploration of human diseases and their genes
inferredcites →https://doi.org/10.1093/eurheartj/ehr350openalex-snapshot
Genetic variants, plasma lipoprotein(a) levels, and risk of cardiovascular morbidity and mortality among two prospective cohorts of type 2 diabetes
inferredcites →https://doi.org/10.1093/hmg/ddu328openalex-snapshot
Mendelian randomization: genetic anchors for causal inference in epidemiological studies
inferredcites →https://doi.org/10.1093/hmg/ddv260openalex-snapshot
Strategies for fine-mapping complex traits
inferredcites →https://doi.org/10.1093/ije/dyg070openalex-snapshot
‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*
inferredcites →https://doi.org/10.1093/ije/dyu176openalex-snapshot
Network Mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways
inferredcites →https://doi.org/10.1093/ije/dyv080openalex-snapshot
Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
inferredcites →https://doi.org/10.1093/ije/dyw314openalex-snapshot
Triangulation in aetiological epidemiology
inferredcites →https://doi.org/10.1093/nar/gkt1229openalex-snapshot
The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
inferredcites →https://doi.org/10.1093/nar/gkv1317openalex-snapshot
GWASdb v2: an update database for human genetic variants identified by genome-wide association studies
inferredcites →https://doi.org/10.1093/nar/gkw1055openalex-snapshot
Open Targets: a platform for therapeutic target identification and validation
inferredcites →https://doi.org/10.1111/dme.12862openalex-snapshot
Lipoprotein(a) predicts a new onset of chronic kidney disease in people with Type 2 diabetes mellitus
inferredcites →https://doi.org/10.1126/science.1262110openalex-snapshot
The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
inferredcites →https://doi.org/10.1136/bmj.d4002openalex-snapshot
Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials
inferredcites →https://doi.org/10.1161/jaha.116.003597openalex-snapshot
Lipoprotein (a)—We Know So Much Yet Still Have Much to Learn …
inferredcites →https://doi.org/10.1186/s13059-016-0926-zopenalex-snapshot
Systematic identification of genetic influences on methylation across the human life course
inferredcites →https://doi.org/10.1371/journal.pgen.1002607openalex-snapshot
Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals
inferredcites →https://doi.org/10.1371/journal.pgen.1004383openalex-snapshot
Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
inferredcites →https://doi.org/10.1371/journal.pone.0108891openalex-snapshot
Using Multivariable Mendelian Randomization to Disentangle the Causal Effects of Lipid Fractions
inferredcites →https://doi.org/10.2337/db13-1144openalex-snapshot
The Association Between Circulating Lipoprotein(a) and Type 2 Diabetes: Is It Causal?
inferredcites →https://doi.org/10.3945/ajcn.115.118216openalex-snapshot
Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1001/jama.2016.21189openalex-snapshot
When Will Mendelian Randomization Become Relevant for Clinical Practice and Public Health?
inferred← citeshttps://doi.org/10.1001/jamapsychiatry.2018.1581openalex-snapshot
Association Between Population Density and Genetic Risk for Schizophrenia
inferred← citeshttps://doi.org/10.1002/9781119099369.ch20openalex-snapshot
Meta‐Analysis in Genetic Association Studies
inferred← citeshttps://doi.org/10.1002/ajmg.b.32689openalex-snapshot
DRD4 methylation as a potential biomarker for physical aggression: An epigenome‐wide, cross‐tissue investigation
inferred← citeshttps://doi.org/10.1002/gepi.22445openalex-snapshot
A two‐sample robust Bayesian Mendelian Randomization method accounting for linkage disequilibrium and idiosyncratic pleiotropy with applications to the COVID‐19 outcomes
inferred← citeshttps://doi.org/10.1002/ijc.31334openalex-snapshot
Polyunsaturated fatty acids and risk of melanoma: A M endelian randomisation analysis
inferred← citeshttps://doi.org/10.1002/jbmr.3320openalex-snapshot
Genetically Determined Later Puberty Impacts Lowered Bone Mineral Density in Childhood and Adulthood
inferred← citeshttps://doi.org/10.1002/jbmr.3605openalex-snapshot
Identification of Novel Loci Associated With Hip Shape: A Meta-Analysis of Genomewide Association Studies
inferred← citeshttps://doi.org/10.1002/jbmr.3989openalex-snapshot
The Effect of Plasma Lipids and Lipid-Lowering Interventions on Bone Mineral Density: A Mendelian Randomization Study
inferred← citeshttps://doi.org/10.1002/per.2153openalex-snapshot
Behaviour Genetic Frameworks of Causal Reasoning for Personality Psychology
inferred← citeshttps://doi.org/10.1007/978-1-4939-7868-7_13openalex-snapshot
A Primer in Mendelian Randomization Methodology with a Focus on Utilizing Published Summary Association Data
inferred← citeshttps://doi.org/10.1007/s00393-019-00742-wopenalex-snapshot
Causal association between periodontitis and risk of rheumatoid arthritis and systemic lupus erythematosus: a Mendelian randomization
inferred← citeshttps://doi.org/10.1007/s00415-018-8972-yopenalex-snapshot
Telomere length as a modifier of age-at-onset in Huntington disease: a two-sample Mendelian randomization study
inferred← citeshttps://doi.org/10.1007/s10067-018-4152-9openalex-snapshot
Vitamin D level and risk of systemic lupus erythematosus and rheumatoid arthritis: a Mendelian randomization
inferred← citeshttps://doi.org/10.1007/s10552-018-1081-5openalex-snapshot
Mendelian randomization does not support serum calcium in prostate cancer risk
inferred← citeshttps://doi.org/10.1007/s10654-018-0385-9openalex-snapshot
Epidemiology in wonderland: Big Data and precision medicine
inferred← citeshttps://doi.org/10.1007/s10654-019-00485-7openalex-snapshot
The association between weight at birth and breast cancer risk revisited using Mendelian randomisation
inferred← citeshttps://doi.org/10.1007/s11892-018-1009-1openalex-snapshot
Prioritising Risk Factors for Type 2 Diabetes: Causal Inference through Genetic Approaches
inferred← citeshttps://doi.org/10.1007/s12035-018-1439-4openalex-snapshot
Exploration of Shared Genetic Architecture Between Subcortical Brain Volumes and Anorexia Nervosa
inferred← citeshttps://doi.org/10.1007/s40471-017-0128-6openalex-snapshot
Recent Developments in Mendelian Randomization Studies
inferred← citeshttps://doi.org/10.1016/j.ajhg.2017.09.003openalex-snapshot
Mendelian Randomization Analysis Identifies CpG Sites as Putative Mediators for Genetic Influences on Cardiovascular Disease Risk
inferred← citeshttps://doi.org/10.1016/j.ajhg.2020.01.015openalex-snapshot
Smoking, DNA Methylation, and Lung Function: a Mendelian Randomization Analysis to Investigate Causal Pathways
inferred← citeshttps://doi.org/10.1016/j.jalz.2019.06.4951openalex-snapshot
Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay
inferred← citeshttps://doi.org/10.1016/j.numecd.2023.02.013openalex-snapshot
The association between leptin and subclinical cardiovascular disease explained by body fat: Observational and Mendelian randomization analyses
inferred← citeshttps://doi.org/10.1016/j.ygeno.2022.110522openalex-snapshot
Causal association between heart failure and bone mineral density: Insights from a two-sample bidirectional Mendelian randomization study
inferred← citeshttps://doi.org/10.1016/j.ymgmr.2019.100539openalex-snapshot
Bi-directional Mendelian randomization of epithelial ovarian cancer and schizophrenia and uni-directional Mendelian randomization of schizophrenia on circulating 1- or 2-glycerophosphocholine metabolites
inferred← citeshttps://doi.org/10.1017/s0033291717002318openalex-snapshot
Embracing polygenicity: a review of methods and tools for psychiatric genetics research
inferred← citeshttps://doi.org/10.1038/nrcardio.2017.78openalex-snapshot
Mendelian randomization in cardiometabolic disease: challenges in evaluating causality
inferred← citeshttps://doi.org/10.1038/nrg.2017.86openalex-snapshot
Statistical and integrative system-level analysis of DNA methylation data
inferred← citeshttps://doi.org/10.1038/s41366-021-00896-1openalex-snapshot
Effects of adiposity on the human plasma proteome: observational and Mendelian randomisation estimates
inferred← citeshttps://doi.org/10.1038/s41416-018-0063-4openalex-snapshot
Height and overall cancer risk and mortality: evidence from a Mendelian randomisation study on 310,000 UK Biobank participants
inferred← citeshttps://doi.org/10.1038/s41430-020-0588-5openalex-snapshot
Effects of tryptophan, serotonin, and kynurenine on ischemic heart diseases and its risk factors: a Mendelian Randomization study
inferred← citeshttps://doi.org/10.1038/s41467-017-00934-5openalex-snapshot
Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity
inferred← citeshttps://doi.org/10.1038/s41467-018-05512-xopenalex-snapshot
Genome‐wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease
inferred← citeshttps://doi.org/10.1038/s41467-018-07743-4openalex-snapshot
GWAS identifies 14 loci for device-measured physical activity and sleep duration
inferred← citeshttps://doi.org/10.1038/s41467-022-34323-4openalex-snapshot
Shared genetic risk factors and causal association between psoriasis and coronary artery disease
inferred← citeshttps://doi.org/10.1038/s41467-023-38234-wopenalex-snapshot
Causal associations between cardiorespiratory fitness and type 2 diabetes
inferred← citeshttps://doi.org/10.1038/s41576-018-0020-3openalex-snapshot
Using genetic data to strengthen causal inference in observational research
inferred← citeshttps://doi.org/10.1038/s41588-017-0013-8openalex-snapshot
Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism
inferred← citeshttps://doi.org/10.1038/s41588-018-0079-yopenalex-snapshot
Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis
inferred← citeshttps://doi.org/10.1038/s41588-018-0255-0openalex-snapshot
Distinguishing genetic correlation from causation across 52 diseases and complex traits
inferred← citeshttps://doi.org/10.1038/s41588-019-0361-7openalex-snapshot
Biological and clinical insights from genetics of insomnia symptoms
inferred← citeshttps://doi.org/10.1038/s41593-018-0206-1openalex-snapshot
GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability
inferred← citeshttps://doi.org/10.1038/s41598-017-10410-1openalex-snapshot
Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity
inferred← citeshttps://doi.org/10.1038/s41598-018-24735-yopenalex-snapshot
Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank
inferred← citeshttps://doi.org/10.1038/s41598-018-25305-yopenalex-snapshot
Assessing causal estimates of the association of obesity-related traits with coronary artery disease using a Mendelian randomization approach
inferred← citeshttps://doi.org/10.1038/s41598-018-25460-2openalex-snapshot
Lack of genetic support for shared aetiology of Coronary Artery Disease and Late-onset Alzheimer’s disease
inferred← citeshttps://doi.org/10.1038/s41598-018-32638-1openalex-snapshot
A genetic perspective on the relationship between eudaimonic –and hedonic well-being
inferred← citeshttps://doi.org/10.1038/s41598-019-39359-zopenalex-snapshot
Investigating causality in the association between vitamin D status and self-reported tiredness
inferred← citeshttps://doi.org/10.1038/s41598-019-44819-7openalex-snapshot
Indoleamine 2,3-dioxygenase and ischemic heart disease: a Mendelian Randomization study
inferred← citeshttps://doi.org/10.1038/s41598-019-52489-8openalex-snapshot
The effect of liver enzymes on adiposity: a Mendelian randomization study
inferred← citeshttps://doi.org/10.1038/s41598-023-33621-1openalex-snapshot
Role of DNA methylation in the relationship between glioma risk factors and glioma incidence: a two-step Mendelian randomization study
inferred← citeshttps://doi.org/10.1038/s41598-025-86222-5openalex-snapshot
Exploring the role of circulating proteins in multiple myeloma risk: a Mendelian randomization study
inferred← citeshttps://doi.org/10.1053/j.ajkd.2017.10.006openalex-snapshot
Challenges in Interpreting Multivariable Mendelian Randomization: Might “Good Cholesterol” Be Good After All?
inferred← citeshttps://doi.org/10.1093/ajcn/nqy101openalex-snapshot
Are serum concentrations of vitamin B-12 causally related to cardiometabolic risk factors and disease? A Mendelian randomization study
inferred← citeshttps://doi.org/10.1093/ajcn/nqy225openalex-snapshot
Circulating antioxidants and Alzheimer disease prevention: a Mendelian randomization study
inferred← citeshttps://doi.org/10.1093/hmg/ddy210openalex-snapshot
Systematic Mendelian randomization framework elucidates hundreds of CpG sites which may mediate the influence of genetic variants on disease
inferred← citeshttps://doi.org/10.1093/hmg/ddy237openalex-snapshot
Consortium-based genome-wide meta-analysis for childhood dental caries traits
inferred← citeshttps://doi.org/10.1093/ije/dyaa183openalex-snapshot
Is disrupted sleep a risk factor for Alzheimer’s disease? Evidence from a two-sample Mendelian randomization analysis
inferred← citeshttps://doi.org/10.1093/ije/dyaa256openalex-snapshot
Investigating the causal effect of maternal vitamin B12 and folate levels on offspring birthweight
inferred← citeshttps://doi.org/10.1093/ije/dyac074openalex-snapshot
Investigating the transparency of reporting in two-sample summary data Mendelian randomization studies using the MR-Base platform
inferred← citeshttps://doi.org/10.1093/ije/dyx028openalex-snapshot
Two-sample Mendelian randomization: avoiding the downsides of a powerful, widely applicable but potentially fallible technique
inferred← citeshttps://doi.org/10.1093/ije/dyx204openalex-snapshot
Software Application Profile: PHESANT: a tool for performing automated phenome scans in UK Biobank
inferred← citeshttps://doi.org/10.1093/ije/dyx207openalex-snapshot
Mendelian randomization: a novel approach for the prediction of adverse drug events and drug repurposing opportunities
inferred← citeshttps://doi.org/10.1093/ije/dyx254openalex-snapshot
Mendelian randomization with Egger pleiotropy correction and weakly informative Bayesian priors
inferred← citeshttps://doi.org/10.1097/jbr.0000000000000104openalex-snapshot
Scrutinizing the causal relationship between schizophrenia and vitamin supplementation: a Mendelian randomization study
inferred← citeshttps://doi.org/10.1101/127993openalex-snapshot
The causal effect of educational attainment on Alzheimer’s disease: A two-sample Mendelian randomization study
inferred← citeshttps://doi.org/10.1101/148627openalex-snapshot
PhenoSpD: an integrated toolkit for phenotypic correlation estimation and multiple testing correction using GWAS summary statistics
inferred← citeshttps://doi.org/10.1101/155739openalex-snapshot
Investigating the role of insulin in increased adiposity: Bi-directional Mendelian randomization study
inferred← citeshttps://doi.org/10.1101/170142openalex-snapshot
Flipping the odds of drug development success through human genomics
inferred← citeshttps://doi.org/10.1101/170241openalex-snapshot
Exploring repositioning opportunities and side-effects of statins: a Mendelian randomization study of HMG-CoA reductase inhibition with 55 complex traits
inferred← citeshttps://doi.org/10.1101/173682openalex-snapshot
Automating Mendelian randomization through machine learning to construct a putative causal map of the human phenome
inferred← citeshttps://doi.org/10.1101/196790openalex-snapshot
Relating C-reactive Protein to Psychopathology after Cardiac Surgery and Intensive Care Unit Admission: A Mendelian Randomization Study
inferred← citeshttps://doi.org/10.1101/2020.11.11.377747openalex-snapshot
Validation of lipid-related therapeutic targets for coronary heart disease prevention using human genetics
inferred← citeshttps://doi.org/10.1101/2023.03.10.23287084openalex-snapshot
Identifying metabolic features of colorectal cancer liability using Mendelian randomization
inferred← citeshttps://doi.org/10.1101/2024.11.26.24317985openalex-snapshot
Investigating causal relationships between loneliness, social isolation and health
inferred← citeshttps://doi.org/10.1101/234294openalex-snapshot
Genome-wide association analysis of lifetime cannabis use (N=184,765) identifies new risk loci, genetic overlap with mental health, and a causal influence of schizophrenia on cannabis use
inferred← citeshttps://doi.org/10.1101/250068openalex-snapshot
The effect of education on adult mortality, health, and income: triangulating across genetic and policy reforms
inferred← citeshttps://doi.org/10.1101/288241openalex-snapshot
Tendency towards being a “Morning person” increases risk of Parkinson’s disease: evidence from Mendelian randomisation
inferred← citeshttps://doi.org/10.1101/304741openalex-snapshot
Testing the causal effects between subjective wellbeing and physical health using Mendelian randomisation
inferred← citeshttps://doi.org/10.1101/473728openalex-snapshot
Epigenetic regulation of PAR4-related platelet activation: mechanistic links between environmental exposure and cardiovascular disease
inferred← citeshttps://doi.org/10.1101/476135openalex-snapshot
A phenome-wide approach to identify causal risk factors for deep vein thrombosis
inferred← citeshttps://doi.org/10.1101/630293openalex-snapshot
A Phenome-wide Mendelian Randomisation study on genetically determined serum urate levels in UK Biobank cohort
inferred← citeshttps://doi.org/10.1111/acps.13614openalex-snapshot
Causal relationship between sex hormone‐binding globulin and major depression: A Mendelian randomization study
inferred← citeshttps://doi.org/10.1111/add.15673openalex-snapshot
Using Mendelian randomization to explore the gateway hypothesis: possible causal effects of smoking initiation and alcohol consumption on substance use outcomes
inferred← citeshttps://doi.org/10.1111/eci.13076openalex-snapshot
Causal association between body mass index and risk of rheumatoid arthritis: A Mendelian randomization study
inferred← citeshttps://doi.org/10.1111/eci.13156openalex-snapshot
Uric acid level, gout and bone mineral density: A Mendelian randomization study
inferred← citeshttps://doi.org/10.1111/jsr.12695openalex-snapshot
Investigating genetic correlations and causal effects between caffeine consumption and sleep behaviours
inferred← citeshttps://doi.org/10.1136/bmj.j4761openalex-snapshot
Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study
inferred← citeshttps://doi.org/10.1136/bmj.k1767openalex-snapshot
Role of obesity in smoking behaviour: Mendelian randomisation study in UK Biobank
inferred← citeshttps://doi.org/10.1136/bmj.k2022openalex-snapshot
Education and myopia: assessing the direction of causality by mendelian randomisation
inferred← citeshttps://doi.org/10.1136/jech-2017-210000openalex-snapshot
Causal associations between body mass index and mental health: a Mendelian randomisation study
inferred← citeshttps://doi.org/10.1136/thoraxjnl-2018-212207openalex-snapshot
Genetic and observational evidence supports a causal role of sex hormones on the development of asthma
inferred← citeshttps://doi.org/10.1146/annurev-clinpsy-050817-084847openalex-snapshot
Polygenic Risk Scores in Clinical Psychology: Bridging Genomic Risk to Individual Differences
inferred← citeshttps://doi.org/10.1158/1055-9965.epi-17-1177openalex-snapshot
Causal Inference in Cancer Epidemiology: What Is the Role of Mendelian Randomization?
inferred← citeshttps://doi.org/10.1158/1055-9965.epi-18-0079openalex-snapshot
Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study
inferred← citeshttps://doi.org/10.1161/circgen.117.001952openalex-snapshot
Association of Genetic Instrumental Variables for Lung Function on Coronary Artery Disease Risk
inferred← citeshttps://doi.org/10.1161/circgen.117.002054openalex-snapshot
Birthweight, Type 2 Diabetes Mellitus, and Cardiovascular Disease
inferred← citeshttps://doi.org/10.1161/jaha.117.005619openalex-snapshot
Vascular Endothelial Growth Factor and Ischemic Heart Disease Risk: A Mendelian Randomization Study
inferred← citeshttps://doi.org/10.1177/0961203318817832openalex-snapshot
Alcohol intake and risk of systemic lupus erythematosus: a Mendelian randomization study
inferred← citeshttps://doi.org/10.1186/s12864-021-07618-xopenalex-snapshot
Population genetic considerations for using biobanks as international resources in the pandemic era and beyond
inferred← citeshttps://doi.org/10.1186/s12920-023-01710-9openalex-snapshot
A phenome-wide approach to identify causal risk factors for deep vein thrombosis
inferred← citeshttps://doi.org/10.1186/s13073-018-0556-zopenalex-snapshot
Red blood cell indices and anaemia as causative factors for cognitive function deficits and for Alzheimer’s disease
inferred← citeshttps://doi.org/10.1186/s13073-019-0613-2openalex-snapshot
Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization
inferred← citeshttps://doi.org/10.1186/s13148-017-0414-7openalex-snapshot
Epigenome-wide association study of asthma and wheeze in childhood and adolescence
inferred← citeshttps://doi.org/10.1212/nxg.0000000000000310openalex-snapshot
Genomic variation in educational attainment modifies Alzheimer disease risk
inferred← citeshttps://doi.org/10.1212/wnl.0000000000004854openalex-snapshot
Circulating insulin-like growth factors and Alzheimer disease
inferred← citeshttps://doi.org/10.12688/wellcomeopenres.10567.1openalex-snapshot
Using Mendelian randomization to determine causal effects of maternal pregnancy (intrauterine) exposures on offspring outcomes: Sources of bias and methods for assessing them
inferred← citeshttps://doi.org/10.12688/wellcomeopenres.16369.1openalex-snapshot
Is vitamin D a modifiable risk factor for dental caries?
inferred← citeshttps://doi.org/10.12688/wellcomeopenres.16369.2openalex-snapshot
Examining the causal association between 25-hydroxyvitamin D and caries in children and adults: a two-sample Mendelian randomization approach
inferred← citeshttps://doi.org/10.1371/journal.pgen.1006944openalex-snapshot
Genetic epidemiology and Mendelian randomization for informing disease therapeutics: Conceptual and methodological challenges
inferred← citeshttps://doi.org/10.1371/journal.pgen.1007081openalex-snapshot
Orienting the causal relationship between imprecisely measured traits using GWAS summary data
inferred← citeshttps://doi.org/10.1371/journal.pgen.1007501openalex-snapshot
Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology
inferred← citeshttps://doi.org/10.1371/journal.pgen.1007601openalex-snapshot
Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain
inferred← citeshttps://doi.org/10.1371/journal.pgen.1009105openalex-snapshot
Inferring causal direction between two traits in the presence of horizontal pleiotropy with GWAS summary data
inferred← citeshttps://doi.org/10.1371/journal.pmed.1002937openalex-snapshot
Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study
inferred← citeshttps://doi.org/10.1371/journal.pone.0177875openalex-snapshot
Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study
inferred← citeshttps://doi.org/10.1371/journal.pone.0212464openalex-snapshot
The analysis of causal relationships between blood lipid levels and BMD
inferred← citeshttps://doi.org/10.1534/genetics.117.300347openalex-snapshot
Testing Genetic Pleiotropy with GWAS Summary Statistics for Marginal and Conditional Analyses
inferred← citeshttps://doi.org/10.18699/vj20.686openalex-snapshot
The GWAS-MAP platform for aggregation of results of genome-wide association studies and the GWAS-MAP|homo database of 70 billion genetic associations of human traits
inferred← citeshttps://doi.org/10.20944/preprints202004.0394.v1openalex-snapshot
Population Genetic Considerations for Using Biobanks as International Resources in the Pandemic Era and Beyond
inferred← citeshttps://doi.org/10.21203/rs.3.rs-122651/v1openalex-snapshot
Validation of lipid-related therapeutic targets for coronary heart disease prevention using human genetics
inferred← citeshttps://doi.org/10.2147/cia.s239350openalex-snapshot
Circulating Glutamine and Alzheimer’s Disease: A Mendelian Randomization Study
inferred← citeshttps://doi.org/10.2217/epi-2018-0091openalex-snapshot
Evidence for DNA Methylation Mediating Genetic Liability to Non-Syndromic Cleft Lip/Palate
inferred← citeshttps://doi.org/10.3389/fcvm.2018.00051openalex-snapshot
Common Methods for Performing Mendelian Randomization
inferred← citeshttps://doi.org/10.3389/fgene.2018.00525openalex-snapshot
Use of Mendelian Randomization for Identifying Risk Factors for Brain Tumors
inferred← citeshttps://doi.org/10.3389/fgene.2020.597420openalex-snapshot
Causal Evaluation of Laboratory Markers in Type 2 Diabetes on Cancer and Vascular Diseases Using Various Mendelian Randomization Tools
inferred← citeshttps://doi.org/10.3389/fgene.2021.660989openalex-snapshot
Verification of the Role of ADAMTS13 in the Cardiovascular Disease Using Two-Sample Mendelian Randomization
inferred← citeshttps://doi.org/10.3390/ijms241914668openalex-snapshot
Exploring PCSK9 Genetic Impact on Lipoprotein(a) via Dual Approaches: Association and Mendelian Randomization
inferred← citeshttps://doi.org/10.3390/jcm7100296openalex-snapshot
Phenomic Impact of Genetically-Determined Euthyroid Function and Molecular Differences between Thyroid Disorders
inferred← citeshttps://doi.org/10.3945/ajcn.117.154104openalex-snapshot
Assessing the causal role of adiposity on disordered eating in childhood, adolescence, and adulthood: a Mendelian randomization analysis
inferred← citeshttps://doi.org/10.7554/elife.58361openalex-snapshot
A Mendelian randomization study of the role of lipoprotein subfractions in coronary artery disease
inferred← citeshttps://doi.org/10.7554/elife.87894openalex-snapshot
Identifying metabolic features of colorectal cancer liability using Mendelian randomization
inferred← citeshttps://doi.org/10.7554/elife.87894.3openalex-snapshot
Identifying metabolic features of colorectal cancer liability using Mendelian randomization
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