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Automating Mendelian randomization through machine learning to construct a putative causal map of the human phenome
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1 of the 54 references listed on this page is in the Retraction Watch database as retracted (export 2026-11-04): 10.1038/srep26105 (notice 2018-02-21).
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/gepi.21965openalex-snapshotConsistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator
inferredcites →https://doi.org/10.1002/sim.7221openalex-snapshotA framework for the investigation of pleiotropy in two‐sample summary data Mendelian randomization
inferredcites →https://doi.org/10.1038/nrg2949openalex-snapshotThe pleiotropic structure of the genotype–phenotype map: the evolvability of complex organisms
inferredcites →https://doi.org/10.1038/nrg2949-c1openalex-snapshotAssessing pleiotropy and its evolutionary consequences: pleiotropy is not necessarily limited, nor need it hinder the evolution of complexity
inferredcites →https://doi.org/10.1038/s41588-018-0099-7openalex-snapshotDetection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases
inferredcites →https://doi.org/10.1038/srep42691openalex-snapshotA Mendelian randomization study of the effect of calcium on coronary artery disease, myocardial infarction and their risk factors
inferredcites →https://doi.org/10.1093/aje/kwt084openalex-snapshotEfficient Design for Mendelian Randomization Studies: Subsample and 2-Sample Instrumental Variable Estimators
inferredcites →https://doi.org/10.1093/ije/dyg070openalex-snapshot‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*
inferredcites →https://doi.org/10.1093/ije/dyv080openalex-snapshotMendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
inferredcites →https://doi.org/10.1093/ije/dyx028openalex-snapshotTwo-sample Mendelian randomization: avoiding the downsides of a powerful, widely applicable but potentially fallible technique
inferredcites →https://doi.org/10.1101/078972openalex-snapshotMR-Base: a platform for systematic causal inference across the phenome using billions of genetic associations
inferredcites →https://doi.org/10.1101/126102openalex-snapshotRobust inference in summary data Mendelian randomisation via the zero modal pleiotropy assumption
inferredcites →https://doi.org/10.1101/127993openalex-snapshotThe causal effect of educational attainment on Alzheimer’s disease: A two-sample Mendelian randomization study
inferredcites →https://doi.org/10.1371/journal.pmed.1001976openalex-snapshotInvestigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study
inferredcites →https://doi.org/10.2337/db16-0418openalex-snapshotBMI as a Modifiable Risk Factor for Type 2 Diabetes: Refining and Understanding Causal Estimates Using Mendelian Randomization
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.112803openalex-snapshotComprehensive analysis of single-cell transcriptomics and genetic factors reveals the mechanisms and preventive strategies for the progression from pulmonary fibrosis to lung cancer
inferred← citeshttps://doi.org/10.1017/s2045796024000593openalex-snapshotMediating pathways between attention deficit hyperactivity disorder and type 2 diabetes mellitus: evidence from a two-step and multivariable Mendelian randomization study
inferred← citeshttps://doi.org/10.1038/s41467-023-44079-0openalex-snapshotGenome-wide association study meta-analysis of blood pressure traits and hypertension in sub-Saharan African populations: an AWI-Gen study
inferred← citeshttps://doi.org/10.1038/s41588-018-0099-7openalex-snapshotDetection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases
inferred← citeshttps://doi.org/10.1038/s41588-022-01165-1openalex-snapshotGenome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention
inferred← citeshttps://doi.org/10.1093/hmg/ddac050openalex-snapshotMulti-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes
inferred← citeshttps://doi.org/10.1093/sleep/zsac003openalex-snapshotAssociations of sleep and circadian phenotypes with COVID-19 susceptibility and hospitalization: an observational cohort study based on the UK Biobank and a two-sample Mendelian randomization study
inferred← citeshttps://doi.org/10.1101/200378openalex-snapshotImproving the visualisation, interpretation and analysis of two-sample summary data Mendelian randomization via the radial plot and radial regression
inferred← citeshttps://doi.org/10.1101/476085openalex-snapshotMR-TRYX: A Mendelian randomization framework that exploits horizontal pleiotropy to infer novel causal pathways
inferred← citeshttps://doi.org/10.1101/589820openalex-snapshotThe causal effect of adiposity on hospital costs: Mendelian Randomization analysis of over 300,000 individuals from the UK Biobank
inferred← citeshttps://doi.org/10.1101/630293openalex-snapshotA Phenome-wide Mendelian Randomisation study on genetically determined serum urate levels in UK Biobank cohort
inferred← citeshttps://doi.org/10.1111/cen.14593openalex-snapshotCausal relationship between polycystic ovary syndrome and coronary artery disease: A Mendelian randomisation study
inferred← citeshttps://doi.org/10.1111/jnc.15937openalex-snapshotThe causal role of circulating amino acids on neurodegenerative disorders: A two‐sample Mendelian randomization study
inferred← citeshttps://doi.org/10.1111/opo.12596openalex-snapshotMendelian randomisation and the goal of inferring causation from observational studies in the vision sciences
inferred← citeshttps://doi.org/10.1371/journal.pmed.1002937openalex-snapshotGenetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study
inferred← citeshttps://doi.org/10.2337/db23-0982openalex-snapshotAssociation Between Low Sex Hormone–Binding Globulin and Increased Risk of Type 2 Diabetes Is Mediated by Increased Visceral and Liver Fat: Results From Observational and Mendelian Randomization Analyses
inferred← citeshttps://doi.org/10.31219/osf.io/6yzs7openalex-snapshotA Mendelian Randomization dictionary: Useful definitions and descriptions for undertaking, understanding and interpreting Mendelian Randomization studies
inferred← citeshttps://doi.org/10.3389/fnut.2023.1047640openalex-snapshotNo evidence of a genetic causal relationship between ankylosing spondylitis and iron homeostasis: A two-sample Mendelian randomization study
inferred← citeshttps://doi.org/10.3410/f.733091753.793549148openalex-snapshotFaculty Opinions recommendation of Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases.
inferred← citeshttps://doi.org/10.7759/cureus.89185openalex-snapshotDissecting the Causal Effects of Helicobacter pylori Serotypes on Gastric Cancer Risk: A Two-Sample Mendelian Randomization Study
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