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Oncologic therapy shapes the fitness landscape of clonal hematopoiesis

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/jamaoncol.2016.1025openalex-snapshot
Breast Cancer Risk From Modifiable and Nonmodifiable Risk Factors Among White Women in the United States
inferredcites →https://doi.org/10.1001/jamaoncol.2018.2297openalex-snapshot
Prevalence of Clonal Hematopoiesis Mutations in Tumor-Only Clinical Genomic Profiling of Solid Tumors
inferredcites →https://doi.org/10.1001/jamaoncol.2018.5625openalex-snapshot
Association of Chemotherapy for Solid Tumors With Development of Therapy-Related Myelodysplastic Syndrome or Acute Myeloid Leukemia in the Modern Era
inferredcites →https://doi.org/10.1002/9781119341154.ch2openalex-snapshot
Radiation Biology for Radiation Oncologists
inferredcites →https://doi.org/10.1016/j.beha.2019.02.005openalex-snapshot
Germline polymorphisms and the risk of therapy-related myeloid neoplasms
inferredcites →https://doi.org/10.1016/j.cell.2012.04.023openalex-snapshot
The Life History of 21 Breast Cancers
inferredcites →https://doi.org/10.1016/j.cell.2013.03.002openalex-snapshot
Lessons from the Cancer Genome
inferredcites →https://doi.org/10.1016/j.cels.2016.07.004openalex-snapshot
Inferring the Mutational History of a Tumor Using Multi-state Perfect Phylogeny Mixtures
inferredcites →https://doi.org/10.1016/j.jmoldx.2014.12.006openalex-snapshot
Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT)
inferredcites →https://doi.org/10.1016/j.stem.2017.07.010openalex-snapshot
Therapy-Related Clonal Hematopoiesis in Patients with Non-hematologic Cancers Is Common and Associated with Adverse Clinical Outcomes
inferredcites →https://doi.org/10.1016/j.stem.2018.10.004openalex-snapshot
PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy
inferredcites →https://doi.org/10.1016/s0959-8049(11)70110-1openalex-snapshot
Identification of Novel Somatic Mutations in SF3B1, a Gene Encoding a Core Component of RNA Splicing Machinery, in Myelodysplasia with Ring Sideroblasts and Other Common Cancers
inferredcites →https://doi.org/10.1016/s1077-9108(08)70618-2openalex-snapshot
Genetic intra-tumour heterogeneity in epithelial ovarian cancer and its implications for molecular diagnosis of tumours
inferredcites →https://doi.org/10.1016/s1470-2045(16)30626-xopenalex-snapshot
Preleukaemic clonal haemopoiesis and risk of therapy-related myeloid neoplasms: a case-control study
inferredcites →https://doi.org/10.1016/s1470-2045(16)30627-1openalex-snapshot
Clonal haemopoiesis and therapy-related myeloid malignancies in elderly patients: a proof-of-concept, case-control study
inferredcites →https://doi.org/10.1038/nature07943openalex-snapshot
The cancer genome
inferredcites →https://doi.org/10.1038/nature10762openalex-snapshot
Clonal evolution in cancer
inferredcites →https://doi.org/10.1038/nature13968openalex-snapshot
Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia
inferredcites →https://doi.org/10.1038/ncomms12484openalex-snapshot
Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults
inferredcites →https://doi.org/10.1038/nrc.2017.60openalex-snapshot
Therapy-related myeloid neoplasms: when genetics and environment collide
inferredcites →https://doi.org/10.1038/s41467-018-02858-0openalex-snapshot
Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential
inferredcites →https://doi.org/10.1038/s41586-018-0317-6openalex-snapshot
Prediction of acute myeloid leukaemia risk in healthy individuals
inferredcites →https://doi.org/10.1038/s41591-018-0081-zopenalex-snapshot
Somatic mutations precede acute myeloid leukemia years before diagnosis
inferredcites →https://doi.org/10.1056/nejm199902043400504openalex-snapshot
Risk of Leukemia after Platinum-Based Chemotherapy for Ovarian Cancer
inferredcites →https://doi.org/10.1056/nejmoa1103283openalex-snapshot
SomaticSF3B1Mutation in Myelodysplasia with Ring Sideroblasts
inferredcites →https://doi.org/10.1056/nejmoa1408617openalex-snapshot
Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes
inferredcites →https://doi.org/10.1056/nejmoa1409405openalex-snapshot
Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
inferredcites →https://doi.org/10.1056/nejmoa1516192openalex-snapshot
Genomic Classification and Prognosis in Acute Myeloid Leukemia
inferredcites →https://doi.org/10.1056/nejmoa1716614openalex-snapshot
Classification and Personalized Prognosis in Myeloproliferative Neoplasms
inferredcites →https://doi.org/10.1073/pnas.222118199openalex-snapshot
Multistage carcinogenesis and the incidence of colorectal cancer
inferredcites →https://doi.org/10.1093/bioinformatics/btr026openalex-snapshot
Quality control and preprocessing of metagenomic datasets
inferredcites →https://doi.org/10.1093/ije/26.suppl_1.s6openalex-snapshot
The EPIC Project: rationale and study design. European Prospective Investigation into Cancer and Nutrition
inferredcites →https://doi.org/10.1093/jnci/78.3.459openalex-snapshot
Leukemia After Therapy With Alkylating Agents for Childhood Cancer2
inferredcites →https://doi.org/10.1093/jnci/djz157openalex-snapshot
Evaluating Clonal Hematopoiesis in Tumor-Infiltrating Leukocytes in Breast Cancer and Secondary Hematologic Malignancies
inferredcites →https://doi.org/10.1093/nar/gky1015openalex-snapshot
COSMIC: the Catalogue Of Somatic Mutations In Cancer
inferredcites →https://doi.org/10.1101/079954openalex-snapshot
iCARE: R package to build, validate and apply absolute risk models
inferredcites →https://doi.org/10.1101/312041openalex-snapshot
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes
inferredcites →https://doi.org/10.1101/569566openalex-snapshot
The evolutionary dynamics and fitness landscape of clonal haematopoiesis
inferredcites →https://doi.org/10.1101/cshperspect.a026625openalex-snapshot
Principles of Reconstructing the Subclonal Architecture of Cancers
inferredcites →https://doi.org/10.1126/science.aay9333openalex-snapshot
The evolutionary dynamics and fitness landscape of clonal hematopoiesis
inferredcites →https://doi.org/10.1126/scitranslmed.aac4428openalex-snapshot
Aging as a driver of leukemogenesis
inferredcites →https://doi.org/10.1158/1078-0432.ccr-18-1201openalex-snapshot
Identification of Clonal Hematopoiesis Mutations in Solid Tumor Patients Undergoing Unpaired Next-Generation Sequencing Assays
inferredcites →https://doi.org/10.1182/blood-2012-08-448068openalex-snapshot
Evolving risk of therapy-related acute myeloid leukemia following cancer chemotherapy among adults in the United States, 1975-2008
inferredcites →https://doi.org/10.1186/s13058-017-0852-3openalex-snapshot
An updated PREDICT breast cancer prognostication and treatment benefit prediction model with independent validation
inferredcites →https://doi.org/10.1200/jco.2010.31.3080openalex-snapshot
Risk of Myelodysplastic Syndromes in People Exposed to Ionizing Radiation: A Retrospective Cohort Study of Nagasaki Atomic Bomb Survivors
inferredcites →https://doi.org/10.1200/jco.2013.54.6119openalex-snapshot
Risk of Marrow Neoplasms After Adjuvant Breast Cancer Therapy: The National Comprehensive Cancer Network Experience
inferredcites →https://doi.org/10.1200/jco.2016.71.6712openalex-snapshot
Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma
inferredcites →https://doi.org/10.1200/po.17.00011openalex-snapshot
OncoKB: A Precision Oncology Knowledge Base
inferredcites →https://doi.org/10.3324/haematol.2018.215269openalex-snapshot
Clonal hematopoiesis and risk of acute myeloid leukemia

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1002/mp.17118openalex-snapshot
A novel method for rapid estimation of active bone marrow dose for radiotherapy patients in epidemiological studies
inferred← citeshttps://doi.org/10.1007/978-3-030-72676-8_1openalex-snapshot
Epidemiology and Etiology of AML
inferred← citeshttps://doi.org/10.1016/j.beha.2020.101144openalex-snapshot
Second malignancies in multiple myeloma; emerging patterns and future directions
inferred← citeshttps://doi.org/10.1016/j.blre.2020.100744openalex-snapshot
The clinical implications of clonal hematopoiesis in hematopoietic cell transplantation
inferred← citeshttps://doi.org/10.1016/j.celrep.2020.108458openalex-snapshot
Clonal Hematopoiesis Before, During, and After Human Spaceflight
inferred← citeshttps://doi.org/10.1016/j.jgo.2020.09.006openalex-snapshot
Integrating clonal haematopoiesis into geriatric oncology: The ARCH between aging, cardiovascular disease and malignancy
inferred← citeshttps://doi.org/10.1016/j.xgen.2024.100744openalex-snapshot
Single-cell DNA sequencing reveals pervasive positive selection throughout preleukemic evolution
inferred← citeshttps://doi.org/10.1038/s41375-020-0896-8openalex-snapshot
Clonal myelopoiesis in the UK Biobank cohort: ASXL1 mutations are strongly associated with smoking
inferred← citeshttps://doi.org/10.1038/s41467-021-24858-3openalex-snapshot
The evolution of hematopoietic cells under cancer therapy
inferred← citeshttps://doi.org/10.1038/s41467-022-31878-0openalex-snapshot
Discovering the drivers of clonal hematopoiesis
inferred← citeshttps://doi.org/10.1101/2025.09.30.679613openalex-snapshot
Impaired IL-10 Receptor Signaling Leads to Inflammation Induced Exhaustion in Hematopoietic Stem Cells
inferred← citeshttps://doi.org/10.1111/bjh.17120openalex-snapshot
Protein phosphatase, Mg2+/Mn2+‐dependent 1D (PPM1D) mutations in haematological cancer
inferred← citeshttps://doi.org/10.1126/science.aay9333openalex-snapshot
The evolutionary dynamics and fitness landscape of clonal hematopoiesis
inferred← citeshttps://doi.org/10.1182/blood.2019000989openalex-snapshot
Clonal hematopoiesis and non-hematologic disorders
inferred← citeshttps://doi.org/10.1182/blood.2019000991openalex-snapshot
Clonal hematopoiesis and risk for hematologic malignancy
inferred← citeshttps://doi.org/10.1182/blood.2019004291openalex-snapshot
What To Tell Your Patient With Clonal Hematopoiesis And Why: Insights From Two Specialized Clinics
inferred← citeshttps://doi.org/10.1182/hem.v17.2.10288openalex-snapshot
Precision Medicine in Clonal Hematopoiesis: New Data on Risk for Transformation
inferred← citeshttps://doi.org/10.1186/s12859-020-03879-7openalex-snapshot
Isabl Platform, a digital biobank for processing multimodal patient data
inferred← citeshttps://doi.org/10.3390/cancers12082292openalex-snapshot
E-Cigarette Exposure Decreases Bone Marrow Hematopoietic Progenitor Cells
inferred← citeshttps://doi.org/10.36401/jipo-21-3openalex-snapshot
Inflammation in Myeloid Malignancies: From Bench to Bedside
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