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Periodontitis and cardiometabolic disorders: The role of lipopolysaccharide and endotoxemia

https://doi.org/10.1111/prd.12433
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The Genomic Organization of the Genes for Human Lipopolysaccharide Binding Protein (LBP) and Bactericidal Permeability Increasing Protein (BPI) Is Highly Conserved
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Lipid A, the Immunostimulatory Principle of Lipopolysaccharides ?
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Lipopolysaccharide Biosynthesis and Transport to the Outer Membrane of Gram-Negative Bacteria
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Trained Innate Immunity and Its Implications for Mucosal Immunity and Inflammation
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Gingival Epithelial Cell Recognition of Lipopolysaccharide
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TLR4 and CD14 trafficking and its influence on LPS-induced pro-inflammatory signaling
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Diabetic nephropathy is associated with low-grade inflammation in Type 1 diabetic patients
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Aberrant gut microbiota composition at the onset of type 1 diabetes in young children
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Exercise and gastrointestinal symptoms: running-induced changes in intestinal permeability and markers of gastrointestinal function in asymptomatic and symptomatic runners
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Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice
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High-fat meals induce systemic cytokine release without evidence of endotoxemia-mediated cytokine production from circulating monocytes or myeloid dendritic cells
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Endotoxemia, nutrition, and cardiometabolic disorders
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Increased systemic elastase and C-reactive protein in aggressive periodontitis (CLOI-D-00160R2)
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Role of the Toll Like Receptor (TLR) Radical Cycle in Chronic Inflammation: Possible Treatments Targeting the TLR4 Pathway
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The role of lipopolysaccharide/toll-like receptor 4 signaling in chronic liver diseases
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Main gut bacterial composition differs between patients with type 1 and type 2 diabetes and non-diabetic adults
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Effect of dexamethasone, indomethacin, and lipopolysaccharide on the secretion of interstitial collagenase and type V collagenase by cultured macrophages
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Cross-reactivity between human sialyl Lewisx oligosaccharide and common causative oral bacteria of infective endocarditis
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The indigenous gastrointestinal microflora
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TNF-α Modulation of Intestinal Epithelial Tight Junction Barrier Is Regulated by ERK1/2 Activation of Elk-1
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Salivary microbiome in non-oral disease: A summary of evidence and commentary
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Clarithromycin reduces recurrent cardiovascular events in subjects without periodontitis
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Extended exposure of lipopolysaccharide fraction from Porphyromonas gingivalis facilitates mononuclear cell adhesion to vascular endothelium via Toll-like receptor-2 dependent mechanism
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A common periodontal pathogen has an adverse association with both acute and stable coronary artery disease
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Saturated fatty acids trigger TLR4-mediated inflammatory response
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The association between plasma endotoxin, endotoxin pathway proteins and outcome after ischemic stroke
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Regulation of lipopolysaccharide-inducible genes by MyD88 and Toll/IL-1 domain containing adaptor inducing IFN-β
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GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
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CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4
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The association of periodontal disease with the complications of diabetes mellitus. A systematic review
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Structure and function: Lipid A modifications in commensals and pathogens
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THP-1 cell line: An in vitro cell model for immune modulation approach
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From Focal Lipid Storage to Systemic Inflammation
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Serum lipopolysaccharides predict advanced liver disease in the general population
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Lipid A Phosphoethanolamine Transferase: Regulation, Structure and Immune Response
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Plasma endotoxin activity rises during ischemic stroke and is associated with worse short-term outcome
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Very low density lipoproteins derived from periodontitis patients facilitate macrophage activation via lipopolysaccharide function
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Increased intestinal permeability, measured by serum zonulin, is associated with metabolic risk markers in overweight pregnant women
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Inflammatory responses of a macrophage/epithelial cell co-culture model to mono and mixed infections with Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia
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Loss of lipopolysaccharide receptor CD14 from the surface of human macrophage-like cells mediated by Porphyromonas gingivalis outer membrane vesicles
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The impact of the inflammatory response on coagulation
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Alkaline phosphatases reduce toxicity of lipopolysaccharides in vivo and in vitro through dephosphorylation
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Distinct mechanisms regulate interstitial collagenase and 92-kDa gelatinase expression in human monocytic-like cells exposed to bacterial endotoxin
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A rapid assay of endotoxin in whole blood using autologous neutrophil dependent chemiluminescence
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Association of endotoxemia with carotid atherosclerosis and cardiovascular disease
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MyD88 Is an Adaptor Protein in the hToll/IL-1 Receptor Family Signaling Pathways
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Structure and function of lipopolysaccharides
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Does the shape of lipid A determine the interaction of LPS with Toll-like receptors?
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The capacity of foodstuffs to induce innate immune activation of human monocytes in vitro is dependent on food content of stimulants of Toll-like receptors 2 and 4
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Toll-like Receptor 4 (TLR4) Modulation by Synthetic and Natural Compounds: An Update
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Intestinal epithelial cells as mediators of the commensal–host immune crosstalk
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Interferon-γ-induced increases in intestinal epithelial macromolecular permeability requires the Src kinase Fyn
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The human immunoglobulin A Fc receptor FcαRI: a multifaceted regulator of mucosal immunity
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Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4
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Inflammation in atherosclerosis
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Inflammation and metabolic disorders
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The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex
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Structure, function and diversity of the healthy human microbiome
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Targeting IL-17 and TH17 cells in chronic inflammation
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Periodontal diseases
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Adipokines in inflammation and metabolic disease
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Selective Sorting of Cargo Proteins into Bacterial Membrane Vesicles
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Altered Toll-like Receptor 2-mediated Endotoxin Tolerance Is Related to Diminished Interferon β Production
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Endogenous lipoproteins impact the response to endotoxin in humans
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Stimulants of Toll-like receptors 2 and 4 are elevated in saliva of periodontitis patients compared with healthy subjects
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Porphyromonas gingivalis‐derived lipopolysaccharide causes excessive hepatic lipid accumulation via activating NF‐κB and JNK signaling pathways
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Spheres of influence: Porphyromonas gingivalis outer membrane vesicles
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What exactly distinguishes aggressive from chronic periodontitis: is it mainly a difference in the degree of bacterial invasiveness?
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Resilience of the oral microbiome
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Periodontitis and cardiometabolic disorders: The role of lipopolysaccharide and endotoxemia
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Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway
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Diversity of the Human Intestinal Microbial Flora
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Direct Proteomic Quantification of the Secretome of Activated Immune Cells
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Transport of Peptide-MHC Class II Complexes in Developing Dendritic Cells
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Trained immunity: A program of innate immune memory in health and disease
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A dysbiotic microbiome triggers T H 17 cells to mediate oral mucosal immunopathology in mice and humans
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Disrupting Gram-Negative Bacterial Outer Membrane Biosynthesis through Inhibition of the Lipopolysaccharide Transporter MsbA
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Endotoxin levels in sera of elderly individuals
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Chlamydial and Periodontal Pathogens Induce Hepatic Inflammation and Fatty Acid Imbalance in Apolipoprotein E-Deficient Mice
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Subgingival Plaque in Periodontal Health Antagonizes at Toll-Like Receptor 4 and Inhibits E-Selectin Expression on Endothelial Cells
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A Novel Class of Lipoprotein Lipase-Sensitive Molecules Mediates Toll-Like Receptor 2 Activation by Porphyromonas gingivalis
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Free Lipid A Isolated from Porphyromonas gingivalis Lipopolysaccharide Is Contaminated with Phosphorylated Dihydroceramide Lipids: Recovery in Diseased Dental Samples
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Inactivation of human serum bactericidal activity by a trypsinlike protease isolated from Porphyromonas gingivalis
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Increased Levels of Soluble CD14 in Sera of Periodontitis Patients
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Host-Pathogen Interactions: Redefining the Basic Concepts of Virulence and Pathogenicity
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Lipopolysaccharide-Binding Protein and Phospholipid Transfer Protein Release Lipopolysaccharides from Gram-Negative Bacterial Membranes
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Improved Innate Immunity of Endotoxin-Tolerant Mice Increases Resistance toSalmonella entericaSerovar Typhimurium Infection despite Attenuated Cytokine Response
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Distribution and Kinetics of Lipoprotein-Bound Endotoxin
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CD14 Is Expressed and Released as Soluble CD14 by Human Intestinal Epithelial Cells In Vitro: Lipopolysaccharide Activation of Epithelial Cells Revisited
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A Functional Virulence Complex Composed of Gingipains, Adhesins, and Lipopolysaccharide Shows High Affinity to Host Cells and Matrix Proteins and Escapes Recognition by Host Immune Systems
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Oral Microbial Ecology and the Role of Salivary Immunoglobulin A
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LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis
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Gastrointestinal and hepatic mechanisms limiting entry and dissemination of lipopolysaccharide into the systemic circulation
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Periodontal therapy favorably modulates the oral-gut-hepatic axis in cirrhosis
inferredcites →https://doi.org/10.1152/physiolgenomics.00128.2004openalex-snapshot
The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades
inferredcites →https://doi.org/10.1155/2011/621484openalex-snapshot
Use of Host- and Bacteria-Derived Salivary Markers in Detection of Periodontitis: A Cumulative Approach
inferredcites →https://doi.org/10.1161/01.atv.0000072969.71452.87openalex-snapshot
Antibodies to Periodontal Pathogens Are Associated With Coronary Heart Disease
inferredcites →https://doi.org/10.1161/01.atv.0000145979.82184.9fopenalex-snapshot
Severe Periodontitis Enhances Macrophage Activation via Increased Serum Lipopolysaccharide
inferredcites →https://doi.org/10.1161/01.atv.0000155018.67835.1aopenalex-snapshot
Human Atherosclerotic Plaque Contains Viable Invasive Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis
inferredcites →https://doi.org/10.1161/atvbaha.106.138743openalex-snapshot
Endotoxemia, Immune Response to Periodontal Pathogens, and Systemic Inflammation Associate With Incident Cardiovascular Disease Events
inferredcites →https://doi.org/10.1161/atvbaha.121.316153openalex-snapshot
Gab2 (Grb2-Associated Binder2) Plays a Crucial Role in Inflammatory Signaling and Endothelial Dysfunction
inferredcites →https://doi.org/10.1161/cir.0b013e31825719f3openalex-snapshot
Periodontal Disease and Atherosclerotic Vascular Disease: Does the Evidence Support an Independent Association?
inferredcites →https://doi.org/10.1161/circ.105.10.1158openalex-snapshot
Expression of Toll-Like Receptors in Human Atherosclerotic Lesions
inferredcites →https://doi.org/10.1161/circresaha.115.306301openalex-snapshot
Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis
inferredcites →https://doi.org/10.1161/circresaha.115.306884openalex-snapshot
Vascular Complications of Diabetes
inferredcites →https://doi.org/10.1161/circulationaha.107.758524openalex-snapshot
Bacteremia Associated With Toothbrushing and Dental Extraction
inferredcites →https://doi.org/10.1161/hc5001.100631openalex-snapshot
Toll-Like Receptor-4 Is Expressed by Macrophages in Murine and Human Lipid-Rich Atherosclerotic Plaques and Upregulated by Oxidized LDL
inferredcites →https://doi.org/10.1161/jaha.121.022482openalex-snapshot
Genetic Profile of Endotoxemia Reveals an Association With Thromboembolism and Stroke
inferredcites →https://doi.org/10.1177/0022034510379019openalex-snapshot
LPS Promotes Pre-osteoclast Activity by Up-regulating CXCR4 via TLR-4
inferredcites →https://doi.org/10.1177/0022034511413928openalex-snapshot
Local Inflammatory Markers and Systemic Endotoxin in Aggressive Periodontitis
inferredcites →https://doi.org/10.1177/0022034515586352openalex-snapshot
Missing Teeth Predict Incident Cardiovascular Events, Diabetes, and Death
inferredcites →https://doi.org/10.1177/09680519010070050801openalex-snapshot
The role of TLR4 in endotoxin responsiveness in humans
inferredcites →https://doi.org/10.1177/09680519030090020701openalex-snapshot
Impact of sepsis-induced changes in plasma on LPS interactions with monocytes and plasma lipoproteins: roles of soluble CD14, LBP, and acute phase lipoproteins
inferredcites →https://doi.org/10.1177/09680519050110060901openalex-snapshot
Synthesis of lipid A and its analogues for investigation of the structural basis for their bioactivity
inferredcites →https://doi.org/10.1177/09680519060120010601openalex-snapshot
Pro-atherogenic properties of lipopolysaccharide from the periodontal pathogen Actinobacillus actinomycetemcomitans
inferredcites →https://doi.org/10.1177/0968051907079118openalex-snapshot
Transcriptional activation of MMP-13 by periodontal pathogenic LPS requires p38 MAP kinase
inferredcites →https://doi.org/10.1177/154405910508400208openalex-snapshot
Design and Validation of Anti-inflammatory Peptides from Human Parotid Secretory Protein
inferredcites →https://doi.org/10.1177/154405910808700908openalex-snapshot
A New Inflammatory Cytokine on the Block: Re-thinking Periodontal Disease and the Th1/Th2 Paradigm in the Context of Th17 Cells and IL-17
inferredcites →https://doi.org/10.1177/1753425908095130openalex-snapshot
Lipopolysaccharide associates with pro-atherogenic lipoproteins in periodontitis patients
inferredcites →https://doi.org/10.1177/1753425908101577openalex-snapshot
Soluble CD14 in periodontitis
inferredcites →https://doi.org/10.1177/1753425912465098openalex-snapshot
Bactericidal/permeability increasing protein: A multifaceted protein with functions beyond LPS neutralization
inferredcites →https://doi.org/10.1177/1753425918796207openalex-snapshot
Salivary biomarkers in association with periodontal parameters and the periodontitis risk haplotype
inferredcites →https://doi.org/10.1177/1753425920971702openalex-snapshot
Endotoxemia is associated with an adverse metabolic profile
inferredcites →https://doi.org/10.1183/13993003.00972-2015openalex-snapshot
Lung exposure to lipopolysaccharide causes atherosclerotic plaque destabilisation
inferredcites →https://doi.org/10.1186/1471-2164-14-709openalex-snapshot
The effect of proatherogenic pathogens on adipose tissue transcriptome and fatty acid distribution in apolipoprotein E-deficient mice
inferredcites →https://doi.org/10.1186/1471-2180-13-73openalex-snapshot
The expression and regulation of matrix metalloproteinase-3 is critically modulated by Porphyromonas gingivalis lipopolysaccharide with heterogeneous lipid A structures in human gingival fibroblasts
inferredcites →https://doi.org/10.1186/1471-230x-12-16openalex-snapshot
Involvement of a periodontal pathogen, Porphyromonas gingivalis on the pathogenesis of non-alcoholic fatty liver disease
inferredcites →https://doi.org/10.1186/1743-7075-11-28openalex-snapshot
Patients with type 1 diabetes show signs of vascular dysfunction in response to multiple high-fat meals
inferredcites →https://doi.org/10.1189/jlb.3mr0316-118rropenalex-snapshot
Molecular mechanisms of innate memory and tolerance to LPS
inferredcites →https://doi.org/10.1189/jlb.3ru0316-151ropenalex-snapshot
Endotoxemia—menace, marker, or mistake?
inferredcites →https://doi.org/10.1194/jlr.d059725openalex-snapshot
Quantitative lipopolysaccharide analysis using HPLC/MS/MS and its combination with the limulus amebocyte lysate assay
inferredcites →https://doi.org/10.1194/jlr.m200361-jlr200openalex-snapshot
Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids
inferredcites →https://doi.org/10.1194/jlr.m300250-jlr200openalex-snapshot
Periodontitis decreases the antiatherogenic potency of high density lipoprotein
inferredcites →https://doi.org/10.1194/jlr.m800156-jlr200openalex-snapshot
Chylomicrons promote intestinal absorption of lipopolysaccharides
inferredcites →https://doi.org/10.1194/jlr.r300019-jlr200openalex-snapshot
Thematic review series: The Pathogenesis of Atherosclerosis. Effects of infection and inflammation on lipid and lipoprotein metabolism mechanisms and consequences to the host
inferredcites →https://doi.org/10.1194/jlr.ra120000704openalex-snapshot
Human cholesteryl ester transfer protein lacks lipopolysaccharide transfer activity, but worsens inflammation and sepsis outcomes in mice
inferredcites →https://doi.org/10.1210/jc.2018-01165openalex-snapshot
Blood Metabolomic Measures Associate With Present and Future Glycemic Control in Type 2 Diabetes
inferredcites →https://doi.org/10.1292/jvms.63.811openalex-snapshot
Mast Cell MMP-9 Production Enhanced by Bacterial Lipopolysaccharide.
inferredcites →https://doi.org/10.1371/journal.pone.0134234openalex-snapshot
Oral Administration of P. gingivalis Induces Dysbiosis of Gut Microbiota and Impaired Barrier Function Leading to Dissemination of Enterobacteria to the Liver
inferredcites →https://doi.org/10.1371/journal.pone.0188475openalex-snapshot
Distinct fecal and oral microbiota composition in human type 1 diabetes, an observational study
inferredcites →https://doi.org/10.1371/journal.pone.0200231openalex-snapshot
Differential profiles of soluble and cellular toll like receptor (TLR)-2 and 4 in chronic periodontitis
inferredcites →https://doi.org/10.1371/journal.pone.0228806openalex-snapshot
Serum lipopolysaccharide neutralizing capacity in ischemic stroke
inferredcites →https://doi.org/10.1371/journal.ppat.1006436openalex-snapshot
Acyloxyacyl hydrolase promotes the resolution of lipopolysaccharide-induced acute lung injury
inferredcites →https://doi.org/10.1373/clinchem.2014.232918openalex-snapshot
GlycA: A Composite Nuclear Magnetic Resonance Biomarker of Systemic Inflammation
inferredcites →https://doi.org/10.1530/jme-13-0079openalex-snapshot
Metabolic endotoxemia: a molecular link between obesity and cardiovascular risk
showing the first 200 of 227 · page through all 227

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4668366openalex-extracted
Engineering of Brewery Waste-Derived Graphene Quantum Dots with Zno Nanoparticles for Treating Multi-Drug Resistant Bacterial Infections
inferred← citeshttps://doi.org/10.1002/adfm.202418928openalex-snapshot
Endotoxin‐Capturing Nitric Oxide‐Releasing Nanoproducers Synergistically Integrated with Photodynamic Therapy for Bacterial Biofilm Infections
inferred← citeshttps://doi.org/10.1002/adhm.202303942openalex-snapshot
“Periodontal ligament‐on‐chip” as a Novel Tool for Studies on the Physiology and Pathology of Periodontal Tissues
inferred← citeshttps://doi.org/10.1002/adhm.202500867openalex-snapshot
Porous Microspheres Loading Small Molecule Targeting REV‐ERBs Modulate Inflammatory Cytokines Fluctuations to Promote Periodontal Bone Regeneration
inferred← citeshttps://doi.org/10.1002/adhm.202502690openalex-snapshot
Complexed Micelles System Based on Ceria Oxide Nanozyme for Bone Remodeling and ROS Scavenging in Periodontitis
inferred← citeshttps://doi.org/10.1002/adma.202519288openalex-snapshot
Macrophages Intracellularly Gelated With Bioactive Hydrogels for Synergistic Neutralization, Eradication, and Osteopromotion in Periodontitis Treatment
inferred← citeshttps://doi.org/10.1002/fsn3.71493openalex-snapshot
Oral Administration of Freeze‐Dried Lactobacillus zeae Alleviates Periodontitis by Affecting the Oral and Intestinal Flora
inferred← citeshttps://doi.org/10.1002/jper.70140openalex-snapshot
Microbial burden of periodontal diseases and its clinical application: The stage, grade, and furcation matter
inferred← citeshttps://doi.org/10.1002/jper.70146openalex-snapshot
Periodontitis aggravates atherosclerosis by inducing inflammatory response and macrophage pyroptosis through the NF‐κB/NLRP3/caspase‐1 pathway
inferred← citeshttps://doi.org/10.1002/osi2.1224openalex-snapshot
Bactericidal activity of slightly acidic electrolyzed water against the cariogenic bacterium Streptococcus mutans and other oral bacteria
inferred← citeshttps://doi.org/10.1007/978-3-031-08115-6_20-1openalex-snapshot
The Other Microbiome: Oral Microbiota and Cardiometabolic Risk
inferred← citeshttps://doi.org/10.1007/978-3-031-35064-1_20openalex-snapshot
The Other Microbiome: Oral Microbiota and Cardiometabolic Risk
inferred← citeshttps://doi.org/10.1007/s00592-024-02335-9openalex-snapshot
Hepatokines: unveiling the molecular and cellular mechanisms connecting hepatic tissue to insulin resistance and inflammation
inferred← citeshttps://doi.org/10.1007/s00604-026-08212-2openalex-snapshot
High-sensitivity electrochemical aptasensor based on AuNPs/NH2-UIO-66/PEI/MCNs nanocomposite for endotoxin detection
inferred← citeshttps://doi.org/10.1007/s00784-022-04502-0openalex-snapshot
Is periodontal inflamed surface area associated with serum and salivary levels of IL-1β, visfatin, and omentin-1 in overweight/obese patients?
inferred← citeshttps://doi.org/10.1007/s00784-022-04563-1openalex-snapshot
Obesity in young women is positively associated with periodontitis
inferred← citeshttps://doi.org/10.1007/s00784-023-04958-8openalex-snapshot
Periodontitis is associated with subclinical cerebral and carotid atherosclerosis in hypertensive patients: A cross-sectional study
inferred← citeshttps://doi.org/10.1007/s00784-023-05174-0openalex-snapshot
Periodontal and cardiovascular therapies modify specialized pro-resolving lipid mediator (sPRLM) (LPXA4, PD1, RvE1, RvD1, and MaR1)-mediated pathway: the first pilot clinical study
inferred← citeshttps://doi.org/10.1007/s00784-023-05300-yopenalex-snapshot
Impact of periodontitis on circulating cell-free DNA levels as a measure of cardiovascular disease
inferred← citeshttps://doi.org/10.1007/s00784-024-05913-xopenalex-snapshot
Current clinical framework on nitric oxide role in periodontal disease and blood pressure
inferred← citeshttps://doi.org/10.1007/s10266-024-00959-5openalex-snapshot
Immunogenic effects of enamel matrix derivative on human alveolar ridge mucosa-derived vascular endothelial cells under lipopolysaccharide stimulation
inferred← citeshttps://doi.org/10.1007/s10266-026-01556-4openalex-snapshot
Association between periodontitis and subclinical vascular dysfunction: a systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1007/s10753-023-01845-yopenalex-snapshot
Small Extracellular Vesicles from Periodontal Ligament Stem Cells Primed by Lipopolysaccharide Regulate Macrophage M1 Polarization via miR-433-3p Targeting TLR2/TLR4/NF-κB
inferred← citeshttps://doi.org/10.1007/s11883-025-01340-9openalex-snapshot
Correlation Between Oral Bacteria and Atherosclerotic Thrombotic Disease: Advances in Animal Model Studies
inferred← citeshttps://doi.org/10.1007/s40521-023-00355-4openalex-snapshot
Does a Dysbiotic Oral Microbiome Trigger the Risk of Chronic Inflammatory Disease?
inferred← citeshttps://doi.org/10.1016/j.apsb.2026.07.021openalex-snapshot
SIRT6 activator MDL-800 alleviates periodontal inflammation by inhibiting AIM2 pathway
inferred← citeshttps://doi.org/10.1016/j.bios.2025.117680openalex-snapshot
Dual-mode electrochemical fiber optic surface plasmon resonance sensor (EC-FO-SPR) for real-time and sensitive detection of lipopolysaccharide
inferred← citeshttps://doi.org/10.1016/j.cej.2025.164349openalex-snapshot
Polycationic nanoparticles for cascaded antibiosis and LPS- detoxifying via co-delivery of antibiotics and TLR siRNA in bacterial infected diseases treatment
inferred← citeshttps://doi.org/10.1016/j.csbj.2024.01.018openalex-snapshot
Microbial functional pathways based on metatranscriptomic profiling enable effective saliva-based health assessments for precision wellness
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2025.117710openalex-snapshot
Thiacloprid exposure disrupts the gut-liver axis and induces liver dysfunction in the Reeves' turtles (Mauremys reevesii)
inferred← citeshttps://doi.org/10.1016/j.foodchem.2024.138916openalex-snapshot
(−)-Epicatechin ameliorates type 2 diabetes mellitus by reshaping the gut microbiota and Gut–Liver axis in GK rats
inferred← citeshttps://doi.org/10.1016/j.identj.2026.109818openalex-snapshot
Periodontitis Exacerbates Insulin Resistance via Gut Barrier Dysfunction and TLR4/NF-κB Activation
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.135371openalex-snapshot
Application of lipopolysaccharide in establishing inflammatory models
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.111558openalex-snapshot
Association between periodontitis and inflammatory comorbidities: The common role of innate immune cells, underlying mechanisms and therapeutic targets
inferred← citeshttps://doi.org/10.1016/j.isci.2023.108465openalex-snapshot
Isolation of Streptococcus mutans temperate bacteriophage with broad killing activity to S. mutans clinical isolates
inferred← citeshttps://doi.org/10.1016/j.jddst.2024.106367openalex-snapshot
Development and in vitro-in vivo performances of an inhalable andrographolide dry powder to target pulmonary inflammation
inferred← citeshttps://doi.org/10.1016/j.jece.2024.112263openalex-snapshot
Engineering of brewery waste-derived graphene quantum dots with ZnO nanoparticles for treating multi-drug resistant bacterial infections
inferred← citeshttps://doi.org/10.1016/j.jhep.2026.04.023openalex-snapshot
Harnessing the oral microbiome in chronic liver disease: Mechanisms, therapeutic modulation and translational frontiers
inferred← citeshttps://doi.org/10.1016/j.lfs.2024.123009openalex-snapshot
Interplay of co-cultured chimeric adipose and gingival tissues exacerbates inflammatory dysfunction relevant to periodontal and metabolic conditions
inferred← citeshttps://doi.org/10.1016/j.lfs.2025.123981openalex-snapshot
The gut microbiota and cardiovascular disease: Exploring the role of microbial dysbiosis and metabolites in pathogenesis and therapeutics
inferred← citeshttps://doi.org/10.1016/j.neucom.2023.126629openalex-snapshot
A review of deep learning in dentistry
inferred← citeshttps://doi.org/10.1016/j.perio.2026.100011openalex-snapshot
Periodontitis and the combined burden of diabetes and liver fibrosis risk: a population-based cross-sectional study
inferred← citeshttps://doi.org/10.1016/j.prmcm.2026.100790openalex-snapshot
Intestinal-hepatic axis-mediated hepatocarcinogenesis and traditional Chinese medicine intervention strategies
inferred← citeshttps://doi.org/10.1016/j.tice.2024.102447openalex-snapshot
ATF3 affects osteogenic differentiation in inflammatory hPDLSCs by mediating ferroptosis via regulating the Nrf2/HO-1 signaling pathway
inferred← citeshttps://doi.org/10.1016/j.tice.2026.103846openalex-snapshot
Dental mesenchymal stem cells under inflammatory condition: A potential candidate for stem cell therapy
inferred← citeshttps://doi.org/10.1038/s41522-023-00441-0openalex-snapshot
The recovery of the microbial community after plaque removal depends on periodontal health status
inferred← citeshttps://doi.org/10.1038/s41598-022-19154-zopenalex-snapshot
Myocardial infarction risk is increased by periodontal pathobionts: a cross-sectional study
inferred← citeshttps://doi.org/10.1038/s41598-024-64771-5openalex-snapshot
Modulation of allograft immune responses by Porphyromonas gingivalis lipopolysaccharide administration in a rat model of kidney transplantation
inferred← citeshttps://doi.org/10.1038/s41598-024-77434-2openalex-snapshot
Salivary features of periodontitis and gingivitis in type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.1038/s41598-025-97531-0openalex-snapshot
Microbiome composition and metabolic pathways in shallow and deep periodontal pockets
inferred← citeshttps://doi.org/10.1055/s-0044-1791845openalex-snapshot
Knowledge of Dental Students about the Association between Periodontal Bacteria and Obesity and Their Attitude toward Obese Patients
inferred← citeshttps://doi.org/10.1080/0886022x.2025.2519816openalex-snapshot
Prediction of postoperative infection through early-stage salivary microbiota following kidney transplantation using machine learning techniques
inferred← citeshttps://doi.org/10.1080/19424396.2023.2193372openalex-snapshot
Oral Cavity is the Gateway to the Body: Role of Oral Health Professionals: A Narrative Review
inferred← citeshttps://doi.org/10.1080/19490976.2026.2672794openalex-snapshot
Gut-derived bacterial extracellular vesicles: the microbial dark matter contributing to host inflammation and cardiometabolic disease
inferred← citeshttps://doi.org/10.1080/20002297.2026.2641915openalex-snapshot
Denture-associated oral microbiome in dentate and edentulous older adults living in long-term care facilities
inferred← citeshttps://doi.org/10.1080/20002297.2026.2705699openalex-snapshot
The oral‒gut axis in periodontal disease: a systematic review of the associated human evidence of its mechanisms and implications for patient care
inferred← citeshttps://doi.org/10.1097/md.0000000000034878openalex-snapshot
A systematic comparison of machine learning algorithms to develop and validate prediction model to predict heart failure risk in middle-aged and elderly patients with periodontitis (NHANES 2009 to 2014)
inferred← citeshttps://doi.org/10.1097/md.0000000000036659openalex-snapshot
A novel nomogram for predicting risk of hypertension in US adults with periodontitis: National Health and Nutrition Examination Survey (NHANES) 2009–2014
inferred← citeshttps://doi.org/10.1111/1756-185x.14794openalex-snapshot
Serum markers of gut permeability and endotoxemia in patients with osteoarthritis of the knee associated with metabolic syndrome
inferred← citeshttps://doi.org/10.1111/jcmm.71337openalex-snapshot
Machine Learning Stratification of Periodontal and Cerebrovascular Disease Status Using Salivary and Subgingival Lipopolysaccharide Activity
inferred← citeshttps://doi.org/10.1111/jcpe.14193openalex-snapshot
Genetic Loci Associated With Periodontitis: The FinnGen Study Based on National Health Registers
inferred← citeshttps://doi.org/10.1111/jcpe.70119openalex-snapshot
Periodontitis Is Associated With Poor Blood Pressure Control in Treated Hypertensive Individuals
inferred← citeshttps://doi.org/10.1111/jcpe.70148openalex-snapshot
Periodontitis and Endotoxemia: Clinical and Microbiological Insights
inferred← citeshttps://doi.org/10.1111/jcpe.70182openalex-snapshot
Systemic Lipidomics Identifies Altered Ceramide–Phospholipid Balance Associated With Periodontitis Severity: A Cross‐Sectional Study With 12‐Year Follow‐Up
inferred← citeshttps://doi.org/10.1111/odi.15014openalex-snapshot
Association between metabolic syndrome and salivary MMP ‐8, myeloperoxidase in periodontitis
inferred← citeshttps://doi.org/10.1111/omi.70002openalex-snapshot
Tolerance Induced by Porphyromonas gingivalis Altered Inflammatory Responses in Mice
inferred← citeshttps://doi.org/10.1111/prd.12430openalex-snapshot
Interconnection of periodontal disease and comorbidities: Evidence, mechanisms, and implications
inferred← citeshttps://doi.org/10.1111/prd.12536openalex-snapshot
Periodontitis and metabolic diseases (diabetes and obesity): Tackling multimorbidity
inferred← citeshttps://doi.org/10.1111/prd.12616openalex-snapshot
Periodontal disease: A systemic condition
inferred← citeshttps://doi.org/10.1128/cmr.00150-24openalex-snapshot
Oral microbiota and respiratory diseases: advances and perspectives
inferred← citeshttps://doi.org/10.1128/mbio.01948-25openalex-snapshot
Metabolic strategies that enable oral commensal persistence in a lower airway environment
inferred← citeshttps://doi.org/10.1128/msystems.01308-22openalex-snapshot
Geographic social vulnerability is associated with the alpha diversity of the human microbiome
inferred← citeshttps://doi.org/10.11606/t.5.2022.tde-13042023-144620openalex-snapshot
Bases celulares e efeitos do tratamento com metotrexato associado a nanopartículas lipídicas sobre as alterações cardiovasculares da endotoxemia induzida por LPS em ratos
inferred← citeshttps://doi.org/10.1161/jaha.125.043495openalex-snapshot
Association of Subgingival Microbiota Composition With Risk, Severity, and Outcome of Cryptogenic Ischemic Stroke in Young Adults
inferred← citeshttps://doi.org/10.1177/00220345241232406openalex-snapshot
Periodontitis, Dental Procedures, and Young-Onset Cryptogenic Stroke
inferred← citeshttps://doi.org/10.1177/00220345241263320openalex-snapshot
The PerioGene North Study Uncovers Serum Proteins Related to Periodontitis
inferred← citeshttps://doi.org/10.1177/00220345251370995openalex-snapshot
Oral Microbial Determinants of Saliva and Serum Lipopolysaccharide Activity
inferred← citeshttps://doi.org/10.1177/19373368251405123openalex-snapshot
Biocompatible Materials for Periodontal Regeneration: Animal Models and Treatment Outcome Assessment
inferred← citeshttps://doi.org/10.1186/s12903-022-02637-wopenalex-snapshot
Severity and progression rate of periodontitis are associated with an increased risk of hypertension of patients attending a university clinic
inferred← citeshttps://doi.org/10.1186/s12903-024-04785-7openalex-snapshot
Effects of stannous fluoride dentifrice on gingival health and oxidative stress markers: a prospective clinical trial
inferred← citeshttps://doi.org/10.1186/s12903-025-05454-zopenalex-snapshot
Dental and oral health assessments in the German National Cohort (NAKO)
inferred← citeshttps://doi.org/10.1186/s12903-025-06261-2openalex-snapshot
Cross-sectional associations between vitamin D status and periodontitis in adults in Northern Norway: The Tromsø Study 2015–2016
inferred← citeshttps://doi.org/10.1186/s12903-025-07407-yopenalex-snapshot
A possible correlation between periodontal disease and systemic diseases: a clinical study
inferred← citeshttps://doi.org/10.1186/s12916-023-03139-4openalex-snapshot
Periodontitis and systemic inflammation as independent and interacting risk factors for mortality: evidence from a prospective cohort study
inferred← citeshttps://doi.org/10.1186/s12967-022-03785-xopenalex-snapshot
The role of the oral microbiome in smoking-related cardiovascular risk: a review of the literature exploring mechanisms and pathways
inferred← citeshttps://doi.org/10.1186/s12967-023-04199-zopenalex-snapshot
Association between lipid-A-producing oral bacteria of different potency and fractional exhaled nitric oxide in a Norwegian population-based adult cohort
inferred← citeshttps://doi.org/10.1186/s12974-025-03664-4openalex-snapshot
Chronic periodontitis and systemic inflammation in the elderly: implications for neurodegeneration
inferred← citeshttps://doi.org/10.1186/s13018-024-04676-1openalex-snapshot
Gentiopicroside ameliorates the lipopolysaccharide-induced inflammatory response and hypertrophy in chondrocytes
inferred← citeshttps://doi.org/10.1186/s40001-023-01301-5openalex-snapshot
Bacterial lipopolysaccharide-induced endothelial activation and dysfunction: a new predictive and therapeutic paradigm for sepsis
inferred← citeshttps://doi.org/10.1515/biol-2022-0541openalex-snapshot
Isoimperatorin alleviates lipopolysaccharide-induced periodontitis by downregulating ERK1/2 and NF-κB pathways
inferred← citeshttps://doi.org/10.1556/030.2025.02505openalex-snapshot
Periodontal pathogens as potential risk factors for systemic diseases: An overview
inferred← citeshttps://doi.org/10.18502/wkmj.v67i2.18748openalex-snapshot
Association Mechanisms Between Periodontal Diseases and Systemic Pathology
inferred← citeshttps://doi.org/10.2147/ijn.s510037openalex-snapshot
Nanodrug Delivery Systems for Direct Clearance or Neutralization of LPS
inferred← citeshttps://doi.org/10.2147/rmhp.s498108openalex-snapshot
The Relationship Between Physical Activity Levels and Periodontal Health Status Among College Students: A Cross-Sectional Study
inferred← citeshttps://doi.org/10.2174/011573403x256094231031074753openalex-snapshot
Cardiovascular Manifestations in Inflammatory Bowel Disease
inferred← citeshttps://doi.org/10.21776/ub.jkb.2023.032.04.1openalex-snapshot
The Potency of Polyphenols Extract of Robusta Coffee Bean (Coffea robusta) on COX-2 Inhibition in Neutrophil Cells
inferred← citeshttps://doi.org/10.26599/fshw.2024.9250383openalex-snapshot
The two-way interaction of tea polyphenols with gut microbiota and their effect on atherosclerosis
inferred← citeshttps://doi.org/10.26599/nr.2025.94907527openalex-snapshot
Multi-scale composite Ag-TiO 2 nanoreactor for long-lasting antibacterial and immunomodulatory therapy of periodontitis
inferred← citeshttps://doi.org/10.32604/biocell.2023.028883openalex-snapshot
Exploring the mechanisms of magnolol in the treatment of periodontitis by integrating network pharmacology and molecular docking
inferred← citeshttps://doi.org/10.3389/fcimb.2021.774665openalex-snapshot
Systemic Antibiotics Influence Periodontal Parameters and Oral Microbiota, But Not Serological Markers
inferred← citeshttps://doi.org/10.3389/fcimb.2024.1408581openalex-snapshot
Role of gut microbiota and metabolomics in the lipid-lowering efficacy of statins among Chinese patients with coronary heart disease and hypercholesterolemia
inferred← citeshttps://doi.org/10.3389/fcvm.2023.1255722openalex-snapshot
Bibliometric research on analysis of links between periodontitis and cardiovascular diseases
inferred← citeshttps://doi.org/10.3389/fcvm.2024.1406220openalex-snapshot
The interaction between oral microbiota and gut microbiota in atherosclerosis
inferred← citeshttps://doi.org/10.3389/fdmed.2022.1106456openalex-snapshot
Oral-systemic immune axis: Crosstalk controlling health and disease
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1726630openalex-snapshot
Pediatric acute-onset neuropsychiatric syndromes and the gut-oral-brain axis: a narrative review of emerging microbiome-immune interactions and therapeutic perspectives
inferred← citeshttps://doi.org/10.3389/fimmu.2026.1852272openalex-snapshot
Beyond receptor activation: biased toll-like receptor signaling in periodontal inflammation and regeneration
inferred← citeshttps://doi.org/10.3389/fmicb.2026.1728315openalex-snapshot
Modulation of LPS-associated virulence activity for reduction of periodontal inflammatory burden
inferred← citeshttps://doi.org/10.3389/fmicb.2026.1906205openalex-snapshot
The subgingival microbiome in periodontitis: from ecological dysbiosis and metabolic reprogramming to precision interventions
inferred← citeshttps://doi.org/10.3389/fphar.2023.1146475openalex-snapshot
Periodontitis may predict the use of prescription medicines later in life, a database study
inferred← citeshttps://doi.org/10.3390/antiox13101260openalex-snapshot
Association Between NOX2-Mediated Oxidative Stress, Low-Grade Endotoxemia, Hypoalbuminemia, and Clotting Activation in COVID-19
inferred← citeshttps://doi.org/10.3390/biomedicines13020402openalex-snapshot
Fatty Acid Binding Protein 4 Could Be a Linking Biomarker Between Periodontitis and Systemic Diseases
inferred← citeshttps://doi.org/10.3390/biomedicines14092051openalex-snapshot
Periodontal Dysbiosis and Premature Atherosclerosis: A Critical Appraisal of the Oral–Gut–Vascular Axis
inferred← citeshttps://doi.org/10.3390/cimb46100675openalex-snapshot
Catecholamines Attenuate LPS-Induced Inflammation through β2 Adrenergic Receptor Activation- and PKA Phosphorylation-Mediated TLR4 Downregulation in Macrophages
inferred← citeshttps://doi.org/10.3390/diagnostics13203184openalex-snapshot
The Role of Dysbiotic Oral Microbiota in Cardiometabolic Diseases: A Narrative Review
inferred← citeshttps://doi.org/10.3390/dj13060227openalex-snapshot
Association Between Oral Microbiota Dysbiosis and the Risk of Dementia: A Systematic Review
inferred← citeshttps://doi.org/10.3390/dj13120590openalex-snapshot
In-Depth Multi-Approach Analysis of WGS Metagenomics Data Reveals Signatures Potentially Explaining Features in Periodontitis Stage Severity
inferred← citeshttps://doi.org/10.3390/ijms241310422openalex-snapshot
The Diagnostic Potential of the Human Blood Microbiome: Are We Dreaming or Awake?
inferred← citeshttps://doi.org/10.3390/ijms26115019openalex-snapshot
Exploring the Healing Powers of Histatins: From Oral Health to Therapeutics
inferred← citeshttps://doi.org/10.3390/ijms26167710openalex-snapshot
The Periodontal–Cardiovascular Disease Association: Molecular Mechanisms and Clinical Implications
inferred← citeshttps://doi.org/10.3390/ijms27146495openalex-snapshot
Candidate Biomarkers Linking Periodontitis with Atherosclerotic and Related Cardiovascular Phenotypes: A Systematic Review Focused on Sex-Specific Evidence
inferred← citeshttps://doi.org/10.3390/jcm11226837openalex-snapshot
Periodontal Therapy in Bariatric Surgery Patients with Periodontitis: Randomized Control Clinical Trial
inferred← citeshttps://doi.org/10.3390/life15030455openalex-snapshot
Microchloropsis gaditana as a Natural Antimicrobial with a One Health Approach to Food Safety in Farmed Salmon
inferred← citeshttps://doi.org/10.3390/metabo13010040openalex-snapshot
Associations between Periodontitis, COVID-19, and Cardiometabolic Complications: Molecular Mechanisms and Clinical Evidence
inferred← citeshttps://doi.org/10.3390/metabo15010035openalex-snapshot
Impact of Periodontitis and Oral Dysbiosis Metabolites in the Modulation of Accelerating Ageing and Human Senescence
inferred← citeshttps://doi.org/10.3390/nu14234945openalex-snapshot
Lactobacillus gasseri RW2014 Ameliorates Hyperlipidemia by Modulating Bile Acid Metabolism and Gut Microbiota Composition in Rats
inferred← citeshttps://doi.org/10.3390/pr11051299openalex-snapshot
Antidiabetic Plants for the Treatment of Type 2 Diabetes Mellitus and Associated Bacterial Infections
inferred← citeshttps://doi.org/10.3892/etm.2023.11963openalex-snapshot
PRMT5 inhibition ameliorates inflammation and promotes the osteogenic differentiation of LPS‑induced periodontal stem cells via STAT3/NF‑κB signaling
inferred← citeshttps://doi.org/10.51847/q3yrqxsuh1openalex-snapshot
Periodontitis as a Marker of Systemic Inflammation and Comorbid Pathology: Data from a Multidisciplinary Screening
inferred← citeshttps://doi.org/10.5217/ir.2023.00104openalex-snapshot
Cardiovascular disease: extraintestinal manifestation of inflammatory bowel disease
inferred← citeshttps://doi.org/10.6084/m9.figshare.24550023openalex-snapshot
Additional file 1 of Periodontitis and systemic inflammation as independent and interacting risk factors for mortality: evidence from a prospective cohort study
inferred← citeshttps://doi.org/10.6084/m9.figshare.26592539openalex-snapshot
Additional file 1 of Association between lipid-A-producing oral bacteria of different potency and fractional exhaled nitric oxide in a Norwegian population-based adult cohort
inferred← citeshttps://doi.org/10.61634/2782-3024-2023-10-10-20openalex-snapshot
The role of the gut microbiota in the development of coronary artery atherosclerosis
inferred← citeshttps://doi.org/10.7759/cureus.63775openalex-snapshot
Role of Nonalcoholic Fatty Liver Disease in Periodontitis: A Bidirectional Relationship
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