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Simultaneous Profiling of 194 Distinct Receptor Transcripts in Human Cells

https://doi.org/10.1126/scisignal.2003624
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1 of the 104 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-21): 10.1038/sj.onc.1207247 (notice 2023-02-09).

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Tumor necrosis factor receptor superfamily member TROY is a novel melanoma biomarker and potential therapeutic target
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Amplification of fgfr4 gene in human breast and gynecological cancers
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Production of IL‐10 by melanoma cells: Examination of its role in immunosuppression mediated by melanoma
inferredcites →https://doi.org/10.1007/bf02893405openalex-snapshot
Expression of Ephb2 and Ephb4 in breast carcinoma
inferredcites →https://doi.org/10.1007/s00011-009-0022-xopenalex-snapshot
Rotavirus and coxsackievirus infection activated different profiles of toll-like receptors and chemokines in intestinal epithelial cells
inferredcites →https://doi.org/10.1007/s00109-010-0619-0openalex-snapshot
TRAIL signaling is mediated by DR4 in pancreatic tumor cells despite the expression of functional DR5
inferredcites →https://doi.org/10.1007/s00262-011-1085-4openalex-snapshot
Tissue expression of Toll-like receptors 2 and 4 in sporadic human colorectal cancer
inferredcites →https://doi.org/10.1007/s10529-006-9084-9openalex-snapshot
Cyclooxygenase-independent effects of aspirin on HT-29 human colon cancer cells, revealed by oligonucleotide microarrays
inferredcites →https://doi.org/10.1007/s10585-004-5458-3openalex-snapshot
Constitutive expression of growth regulated oncogene (gro) in human colon carcinoma cells with different metastatic potential and its role in regulating their metastatic phenotype
inferredcites →https://doi.org/10.1007/s10585-006-9045-7openalex-snapshot
Patterns of EphA2 protein expression in primary and metastatic pancreatic carcinoma and correlation with genetic status
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Clonal variants of PC12 pheochromocytoma cells with altered response to nerve growth factor
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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
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The Response of Human Epithelial Cells to TNF Involves an Inducible Autocrine Cascade
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CXCL8 modulates human intestinal epithelial cells through a CXCR1 dependent pathway
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TNFR and LTβR agonists induce follicle-associated epithelium and M cell specific genes in rat and human intestinal epithelial cells
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Profiles of chemokine receptors in melanocytic lesions: de novo expression of CXCR6 in melanoma
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Eph receptors and their ephrin ligands are expressed in developing mouse pancreas
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Persistent Sonic Hedgehog Signaling in Adult Brain Determines Neural Stem Cell Positional Identity
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Cloning and characterization of HTK, a novel transmembrane tyrosine kinase of the EPH subfamily.
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Independent mechanisms account for the regulation by protein kinase C of the epidermal growth factor receptor affinity and tyrosine-protein kinase activity.
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The IIIb isoform of fibroblast growth factor receptor 2 is required for proper growth and branching of pancreatic ductal epithelium but not for differentiation of exocrine or endocrine cells
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Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
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A Muscle-Specific Insulin Receptor Knockout Exhibits Features of the Metabolic Syndrome of NIDDM without Altering Glucose Tolerance
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Expression of growth hormone receptor in benign and malignant cutaneous proliferative entities Note
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The ins and outs of signalling
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Systematic variation in gene expression patterns in human cancer cell lines
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Expression of the ERBB3 gene product in breast cancer
inferredcites →https://doi.org/10.1038/bjc.1994.469openalex-snapshot
Expression of interleukin 10 in human melanoma
inferredcites →https://doi.org/10.1038/msb.2009.93openalex-snapshot
A global view of protein expression in human cells, tissues, and organs
inferredcites →https://doi.org/10.1038/msb.2010.106openalex-snapshot
Defining the transcriptome and proteome in three functionally different human cell lines
inferredcites →https://doi.org/10.1038/msb.2011.28openalex-snapshot
RNA sequencing reveals two major classes of gene expression levels in metazoan cells
inferredcites →https://doi.org/10.1038/nature06001openalex-snapshot
Common effector processing mediates cell-specific responses to stimuli
inferredcites →https://doi.org/10.1038/nature08999openalex-snapshot
Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay
inferredcites →https://doi.org/10.1038/nbt.1754openalex-snapshot
Integrative genomics viewer
inferredcites →https://doi.org/10.1038/nbt0710-681openalex-snapshot
Paring down signaling complexity
inferredcites →https://doi.org/10.1038/nbt1239openalex-snapshot
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements
inferredcites →https://doi.org/10.1038/nm1627openalex-snapshot
Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL
inferredcites →https://doi.org/10.1038/nmeth.1226openalex-snapshot
Mapping and quantifying mammalian transcriptomes by RNA-Seq
inferredcites →https://doi.org/10.1038/nmeth.1442openalex-snapshot
Identifying single-cell molecular programs by stochastic profiling
inferredcites →https://doi.org/10.1038/nmeth.1638openalex-snapshot
A public genome-scale lentiviral expression library of human ORFs
inferredcites →https://doi.org/10.1038/nmeth977openalex-snapshot
Sensitive and specific method for detecting G protein–coupled receptor mRNAs
inferredcites →https://doi.org/10.1038/nrg2484openalex-snapshot
RNA-Seq: a revolutionary tool for transcriptomics
inferredcites →https://doi.org/10.1038/nrn2755openalex-snapshot
Emerging roles of Wnts in the adult nervous system
inferredcites →https://doi.org/10.1038/sj.bjc.6604473openalex-snapshot
FGF10/FGFR2 signal induces cell migration and invasion in pancreatic cancer
inferredcites →https://doi.org/10.1038/sj.onc.1207247openalex-snapshot
RETRACTED ARTICLE: EphA2: a determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinoma
inferredcites →https://doi.org/10.1046/j.1365-2567.2002.01363.xopenalex-snapshot
Interleukin‐10 promotes B16‐melanoma growth by inhibition of macrophage functions and induction of tumour and vascular cell proliferation
inferredcites →https://doi.org/10.1053/gast.1999.0029900359openalex-snapshot
Chemokine receptor expression by human intestinal epithelial cells
inferredcites →https://doi.org/10.1073/pnas.1103423108openalex-snapshot
Intersection of FOXO- and RUNX1-mediated gene expression programs in single breast epithelial cells during morphogenesis and tumor progression
inferredcites →https://doi.org/10.1073/pnas.1537685100openalex-snapshot
The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation
inferredcites →https://doi.org/10.1073/pnas.74.2.565openalex-snapshot
Nerve growth factor receptors on human melanoma cells in culture.
inferredcites →https://doi.org/10.1073/pnas.92.9.3814openalex-snapshot
In situ isolation of mRNA from individual plant cells: creation of cell-specific cDNA libraries.
inferredcites →https://doi.org/10.1074/jbc.m112.348904openalex-snapshot
The Cytosolic Domain of Protein-tyrosine Kinase 7 (PTK7), Generated from Sequential Cleavage by a Disintegrin and Metalloprotease 17 (ADAM17) and γ-Secretase, Enhances Cell Proliferation and Migration in Colon Cancer Cells
inferredcites →https://doi.org/10.1074/mcp.m500158-mcp200openalex-snapshot
A Compendium of Signals and Responses Triggered by Prodeath and Prosurvival Cytokines
inferredcites →https://doi.org/10.1084/jem.20051848openalex-snapshot
The BRAF–MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells
inferredcites →https://doi.org/10.1093/bioinformatics/bti623openalex-snapshot
ROCR: visualizing classifier performance in R
inferredcites →https://doi.org/10.1093/bioinformatics/btq033openalex-snapshot
BEDTools: a flexible suite of utilities for comparing genomic features
inferredcites →https://doi.org/10.1093/bioinformatics/bts134openalex-snapshot
JETTA: junction and exon toolkits for transcriptome analysis
inferredcites →https://doi.org/10.1093/bioinformatics/bts635openalex-snapshot
STAR: ultrafast universal RNA-seq aligner
inferredcites →https://doi.org/10.1093/emboj/19.13.3159openalex-snapshot
The ErbB signaling network: receptor heterodimerization in development and cancer
inferredcites →https://doi.org/10.1093/hmg/8.10.1893openalex-snapshot
Nonsense-mediated mRNA decayin health and disease
inferredcites →https://doi.org/10.1093/humrep/dep028openalex-snapshot
Decoy receptor 3 expression during the menstrual cycle and pregnancy, and regulation by sex steroids in endometrial cells in vitro
inferredcites →https://doi.org/10.1093/ndt/gfr698openalex-snapshot
Lack of expression and function of erythropoietin receptors in the kidney
inferredcites →https://doi.org/10.1097/00006676-200107000-00011openalex-snapshot
Pancreatic Adenocarcinoma Cell Lines Show Variable Susceptibility to TRAIL-Mediated Cell Death
inferredcites →https://doi.org/10.1097/mpa.0b013e31818db9e3openalex-snapshot
High TRAIL Death Receptor 4 and Decoy Receptor 2 Expression Correlates With Significant Cell Death in Pancreatic Ductal Adenocarcinoma Patients
inferredcites →https://doi.org/10.1101/gad.7.8.1632openalex-snapshot
A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation.
inferredcites →https://doi.org/10.1101/gr.3820805openalex-snapshot
Gene expression profiling in single cells from the pancreatic islets of Langerhans reveals lognormal distribution of mRNA levels
inferredcites →https://doi.org/10.1126/science.1116598openalex-snapshot
A Systems Model of Signaling Identifies a Molecular Basis Set for Cytokine-Induced Apoptosis
inferredcites →https://doi.org/10.1126/science.1160342openalex-snapshot
A Global View of Gene Activity and Alternative Splicing by Deep Sequencing of the Human Transcriptome
inferredcites →https://doi.org/10.1126/science.289.5487.2122openalex-snapshot
Role of Brain Insulin Receptor in Control of Body Weight and Reproduction
inferredcites →https://doi.org/10.1126/science.7533326openalex-snapshot
The Fas Death Factor
inferredcites →https://doi.org/10.1126/stke.2003.187.re9openalex-snapshot
Signaling Receptome: A Genomic and Evolutionary Perspective of Plasma Membrane Receptors Involved in Signal Transduction
inferredcites →https://doi.org/10.1128/mcb.10.12.6316openalex-snapshot
cDNA Cloning and Characterization of eck, an Epithelial Cell Receptor Protein-Tyrosine Kinase in the eph/elk Family of Protein Kinases
inferredcites →https://doi.org/10.1136/gut.2006.118679openalex-snapshot
Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease
inferredcites →https://doi.org/10.1152/ajpgi.00347.2002openalex-snapshot
Conjugated linoleic acid inhibits cell proliferation and ErbB3 signaling in HT-29 human colon cell line
inferredcites →https://doi.org/10.1152/ajpgi.1995.268.3.g431openalex-snapshot
Expression of prolactin and growth hormone receptor genes and their isoforms in the gastrointestinal tract
inferredcites →https://doi.org/10.1152/ajpgi.1997.272.5.g1201openalex-snapshot
Interleukin-15 signals T84 colonic epithelial cells in the absence of the interleukin-2 receptor beta-chain
inferredcites →https://doi.org/10.1152/ajpgi.1999.276.3.g599openalex-snapshot
Fas activates the JNK pathway in human colonic epithelial cells: lack of a direct role in apoptosis
inferredcites →https://doi.org/10.1158/0008-5472.can-06-4128openalex-snapshot
The RON Receptor Tyrosine Kinase Mediates Oncogenic Phenotypes in Pancreatic Cancer Cells and Is Increasingly Expressed during Pancreatic Cancer Progression
inferredcites →https://doi.org/10.1158/0008-5472.can-08-2944openalex-snapshot
Sustained Src Inhibition Results in Signal Transducer and Activator of Transcription 3 (STAT3) Activation and Cancer Cell Survival via Altered Janus-Activated Kinase–STAT3 Binding
inferredcites →https://doi.org/10.1158/1541-7786.mcr-11-0279openalex-snapshot
Constitutive Aberrant Endogenous Interleukin-1 Facilitates Inflammation and Growth in Human Melanoma
inferredcites →https://doi.org/10.1172/jci6685openalex-snapshot
Expression of functional CXCR4 chemokine receptors on human colonic epithelial cells
inferredcites →https://doi.org/10.1186/gb-2007-8-4-r64openalex-snapshot
Discovery of tissue-specific exons using comprehensive human exon microarrays
inferredcites →https://doi.org/10.1186/gb-2007-8-5-r82openalex-snapshot
Exon arrays provide accurate assessments of gene expression
inferredcites →https://doi.org/10.1210/en.136.4.1355openalex-snapshot
Quantitative analysis by polymerase chain reaction of growth hormone receptor gene expression in human liver and muscle
inferredcites →https://doi.org/10.1210/me.2007-0087openalex-snapshot
Matching Receptome Genes with Their Ligands for Surveying Paracrine/Autocrine Signaling Systems
inferredcites →https://doi.org/10.1242/dev.052993openalex-snapshot
Epithelial dynamics of pancreatic branching morphogenesis
inferredcites →https://doi.org/10.1371/journal.pcbi.1000598openalex-snapshot
An Abundance of Ubiquitously Expressed Genes Revealed by Tissue Transcriptome Sequence Data
inferredcites →https://doi.org/10.1371/journal.pone.0002583openalex-snapshot
Nonsense-Mediated mRNA Decay Impacts MSI-Driven Carcinogenesis and Anti-Tumor Immunity in Colorectal Cancers
inferredcites →https://doi.org/10.1371/journal.pone.0012243openalex-snapshot
Examination of Apoptosis Signaling in Pancreatic Cancer by Computational Signal Transduction Analysis
inferredcites →https://doi.org/10.1385/1-59259-192-2:365openalex-snapshot
Primer3 on the WWW for General Users and for Biologist Programmers
inferredcites →https://doi.org/10.1523/jneurosci.4570-04.2005openalex-snapshot
Trafficking of a Ligand-Receptor Complex on the Growth Cones as an Essential Step for the Uptake of Nerve Growth Factor at the Distal End of the Axon: A Single-Molecule Analysis
inferredcites →https://doi.org/10.1529/biophysj.104.053330openalex-snapshot
Single-Molecule Analysis of Epidermal Growth Factor Signaling that Leads to Ultrasensitive Calcium Response
inferredcites →https://doi.org/10.1677/erc-07-0080openalex-snapshot
Fibroblast growth factor receptor 4 predicts failure on tamoxifen therapy in patients with recurrent breast cancer
inferredcites →https://doi.org/10.1677/joe.0.1650067openalex-snapshot
Expression of ErbB receptors during pancreatic islet development and regrowth
inferredcites →https://doi.org/10.2174/138945012800564158openalex-snapshot
Targeting EGFR in Pancreatic Cancer Treatment
inferredcites →https://doi.org/10.2337/db05-1073openalex-snapshot
FGFR3 Is a Negative Regulator of the Expansion of Pancreatic Epithelial Cells
inferredcites →https://doi.org/10.3892/ijmm.20.5.689openalex-snapshot
Genes regulated by interferon-γ in human uterine microvascular endothelial cells
inferredcites →https://doi.org/10.3892/ijo.19.1.71openalex-snapshot
Altered expression of TGFB receptors and mitogenic effects of TGFB in pancreatic carcinomas
inferredcites →https://doi.org/10.3892/or.2012.1790openalex-snapshot
Expression of the co-signaling molecules CD40-CD40L and their growth inhibitory effect on pancreatic cancer in vitro
inferredcites →https://doi.org/10.3892/or_00000210openalex-snapshot
Overexpression of the fibroblast growth factor receptor-1 gene correlates with liver metastasis in colorectal cancer
inferredcites →https://doi.org/10.4049/jimmunol.170.3.1406openalex-snapshot
Human Intestinal Epithelial Cells Are Broadly Unresponsive to Toll-Like Receptor 2-Dependent Bacterial Ligands: Implications for Host-Microbial Interactions in the Gut
inferredcites →https://doi.org/10.4049/jimmunol.177.7.4530openalex-snapshot
STAT1-Independent Cell Type-Specific Regulation of Antiviral APOBEC3G by IFN-α
inferredcites →https://doi.org/10.4161/cam.20655openalex-snapshot
Irradiation affects cellular properties and Eph receptor expression in human melanoma cells
inferredcites →https://doi.org/10.4161/cc.10.20.18029openalex-snapshot
RUNX1 and its understudied role in breast cancer

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Association of Intestinal Alkaline Phosphatase With Necrotizing Enterocolitis Among Premature Infants
inferred← citeshttps://doi.org/10.1007/s13311-022-01313-9openalex-snapshot
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Activation of Oncogenic Super-Enhancers Is Coupled with DNA Repair by RAD51
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Single-cell states versus single-cell atlases — two classes of heterogeneity that differ in meaning and method
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Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer
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Chimeric Antigen Receptor-modified T cells targeting EphA2 for the immunotherapy of paediatric bone tumours
inferred← citeshttps://doi.org/10.1038/s41420-019-0228-9openalex-snapshot
Disulfide bond-disrupting agents activate the tumor necrosis family-related apoptosis-inducing ligand/death receptor 5 pathway
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An ultrasensitive fiveplex activity assay for cellular kinases
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Fibroblasts secrete Slit2 to inhibit fibrocyte differentiation and fibrosis
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Fusion transcriptome profiling provides insights into alveolar rhabdomyosarcoma
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Receptor Level Mechanisms Are Required for Epidermal Growth Factor (EGF)-stimulated Extracellular Signal-regulated Kinase (ERK) Activity Pulses
inferred← citeshttps://doi.org/10.1093/nar/gkae164openalex-snapshot
DNA fragility at topologically associated domain boundaries is promoted by alternative DNA secondary structure and topoisomerase II activity
inferred← citeshttps://doi.org/10.1093/nar/gkt965openalex-snapshot
Non-biased and efficient global amplification of a single-cell cDNA library
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Recurrent chimeric fusion RNAs in non-cancer tissues and cells
inferred← citeshttps://doi.org/10.1101/700906openalex-snapshot
Mechanistic Elucidation of the Antitumor Properties of a Novel Death Receptor 5 Activator
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TNF-insulin crosstalk at the transcription factor GATA6 is revealed by a model that links signaling and transcriptomic data tensors
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IL10RA Modulates Crizotinib Sensitivity in NPM1-ALK-positive Anaplastic Large Cell Lymphoma
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Scalable microfluidics for single-cell RNA printing and sequencing
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EVI/WLS function is regulated by ubiquitylation and is linked to ER-associated degradation by ERLIN2
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TGFBR3 supports anoikis through suppressing ATF4 signaling
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A Module of Human Peripheral Blood Mononuclear Cell Transcriptional Network Containing Primitive and Differentiation Markers Is Related to Specific Cardiovascular Health Variables
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Genetically Modified Cellular Therapies for Malignant Gliomas
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Chimeric antigen receptor T cells in the treatment of osteosarcoma (Review)
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TGFβ signaling systems are prone to inhibition and ligand competition by coreceptor
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Regulation of Podocyte Injury by CircHIPK3/FUS Complex in Diabetic Kidney Disease
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