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Cholesterol: Its Regulation and Role in Central Nervous System Disorders

https://doi.org/10.1155/2012/292598

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/archneur.59.2.213openalex-snapshot

Reduction of Plasma 24S-Hydroxycholesterol (Cerebrosterol) Levels Using High-Dosage Simvastatin in Patients With Hypercholesterolemia

inferredcites →https://doi.org/10.1001/archneur.59.3.378openalex-snapshot

Serum Lipoprotein Levels, Statin Use, and Cognitive Function in Older Women

inferredcites →https://doi.org/10.1001/archneur.60.4.510openalex-snapshot

Reduction in Levels of 24S-Hydroxycholesterol by Statin Treatment in Patients With Alzheimer Disease

inferredcites →https://doi.org/10.1001/archneur.62.7.1047openalex-snapshot

Statin Use and the Risk of Incident Dementia

inferredcites →https://doi.org/10.1001/archneurol.2010.199openalex-snapshot

3-Hydroxy-3-methylglutaryl–Coenzyme A Reductase Inhibitors in the Treatment of Central Nervous System Diseases

inferredcites →https://doi.org/10.1001/archneurol.2011.242openalex-snapshot

Cholesterol Level and Statin Use in Alzheimer Disease

inferredcites →https://doi.org/10.1001/jama.283.12.1571openalex-snapshot

Correlation Between Elevated Levels of Amyloid β-Peptide in the Brain and Cognitive Decline

inferredcites →https://doi.org/10.1002/1097-0029(20000815)50:4<316::aid-jemt11>3.0.co;2-eopenalex-snapshot

Influence of lipoproteins on microglial degradation of Alzheimer's amyloid beta-protein

inferredcites →https://doi.org/10.1002/ana.10292openalex-snapshot

Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26‐week randomized, placebo‐controlled, double‐blind trial

inferredcites →https://doi.org/10.1002/bies.10195openalex-snapshot

Outsourcing in the brain: Do neurons depend on cholesterol delivery by astrocytes?

inferredcites →https://doi.org/10.1002/glia.20769openalex-snapshot

Lovastatin induces the formation of abnormal myelin‐like membrane sheets in primary oligodendrocytes

inferredcites →https://doi.org/10.1002/gps.3797openalex-snapshot

Cochrane review on ‘Statins for the treatment of dementia’

inferredcites →https://doi.org/10.1002/hipo.20548openalex-snapshot

Cholesterol‐promoted synaptogenesis requires the conversion of cholesterol to estradiol in the hippocampus

inferredcites →https://doi.org/10.1002/jnr.20607openalex-snapshot

Traumatic brain injury induces biphasic upregulation of ApoE and ApoJ protein in rats

inferredcites →https://doi.org/10.1002/jnr.490180208openalex-snapshot

Metabolism of cholesterol and triacylglycerol in cultured chick neuronal cells, glial cells, and fibroblasts: Accumulation of esterified cholesterol in serum‐free culture

inferredcites →https://doi.org/10.1006/bbrc.2001.2008openalex-snapshot

Membrane-Bound Enzymes of Cholesterol Synthesis from Lanosterol

inferredcites →https://doi.org/10.1006/exnr.1998.6818openalex-snapshot

Evidence for Normal Aging of the Septo-Hippocampal Cholinergic System in apoE (−/−) Mice but Impaired Clearance of Axonal Degeneration Products Following Injury

inferredcites →https://doi.org/10.1007/3-540-29623-9_8735openalex-snapshot

Smith-Lemli-Opitz Syndrome

inferredcites →https://doi.org/10.1007/978-1-4615-5901-6_7openalex-snapshot

Cholesterol and Myelin

inferredcites →https://doi.org/10.1007/bf02527711openalex-snapshot

Origin of cholesterol in myelin

inferredcites →https://doi.org/10.1007/s00415-009-5271-7openalex-snapshot

Pravastatin and cognitive function in the elderly. Results of the PROSPER study

inferredcites →https://doi.org/10.1007/s11064-009-0054-1openalex-snapshot

BACE and γ-Secretase Characterization and Their Sorting as Therapeutic Targets to Reduce Amyloidogenesis

inferredcites →https://doi.org/10.1007/s12013-011-9264-7openalex-snapshot

Effects of Atorvastatin on Pathological Changes in Brain Tissue and Plasma MMP-9 in Rats with Intracerebral Hemorrhage

inferredcites →https://doi.org/10.1007/s12035-010-8099-3openalex-snapshot

Changes in Brain Cholesterol Metabolome After Excitotoxicity

inferredcites →https://doi.org/10.1016/0005-2760(87)90295-5openalex-snapshot

Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins

inferredcites →https://doi.org/10.1016/0014-5793(90)81107-yopenalex-snapshot

Rates of cholesterol, ubiquinone, dolichol and dolichyl‐P biosynthesis in rat brain slices

inferredcites →https://doi.org/10.1016/0021-9150(92)90235-9openalex-snapshot

Human serum gangliosides in hypercholesterolemia, before and after extracorporeal elimination of LDL

inferredcites →https://doi.org/10.1016/0092-8674(84)90188-0openalex-snapshot

The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

inferredcites →https://doi.org/10.1016/j.ajog.2012.06.003openalex-snapshot

The origin of fetal sterols in second-trimester amniotic fluid: endogenous synthesis or maternal-fetal transport?

inferredcites →https://doi.org/10.1016/j.amjmed.2004.07.041openalex-snapshot

Randomized trial of the effects of simvastatin on cognitive functioning in hypercholesterolemic adults

inferredcites →https://doi.org/10.1016/j.amjmed.2009.08.015openalex-snapshot

Higher Incidence of Mild Cognitive Impairment in Familial Hypercholesterolemia

inferredcites →https://doi.org/10.1016/j.bbalip.2010.03.011openalex-snapshot

Brain cholesterol in normal and pathological aging

inferredcites →https://doi.org/10.1016/j.bbrc.2007.04.135openalex-snapshot

Differential effects of cholesterol and 7-dehydrocholesterol on the ligand binding activity of the hippocampal serotonin1A receptor: Implications in SLOS

inferredcites →https://doi.org/10.1016/j.bbrc.2007.08.109openalex-snapshot

cAMP-induced expression of ABCA1 is associated with MAP-kinase-pathway activation

inferredcites →https://doi.org/10.1016/j.brainres.2010.11.067openalex-snapshot

Atorvastatin and pitavastatin improve cognitive function and reduce senile plaque and phosphorylated tau in aged APP mice

inferredcites →https://doi.org/10.1016/j.brainresrev.2009.05.007openalex-snapshot

Clusterin: A forgotten player in Alzheimer's disease

inferredcites →https://doi.org/10.1016/j.devbrainres.2003.09.015openalex-snapshot

Ontogenesis and regulation of cholesterol metabolism in the central nervous system of the mouse

inferredcites →https://doi.org/10.1016/j.febslet.2006.07.027openalex-snapshot

Defects of cholesterol biosynthesis

inferredcites →https://doi.org/10.1016/j.jacl.2009.11.003openalex-snapshot

Altered cholesterol and fatty acid metabolism in Huntington disease

inferredcites →https://doi.org/10.1016/j.jacl.2012.04.079openalex-snapshot

Genetic determinants of cardiometabolic risk: A proposed model for phenotype association and interaction

inferredcites →https://doi.org/10.1016/j.jns.2004.11.036openalex-snapshot

Cholesterol homeostasis failure as a unifying cause of synaptic degeneration

inferredcites →https://doi.org/10.1016/j.jns.2009.02.352openalex-snapshot

Therapeutic potential of statins in Alzheimer's disease

inferredcites →https://doi.org/10.1016/j.mam.2009.02.001openalex-snapshot

Oxysterols and neurodegenerative diseases

inferredcites →https://doi.org/10.1016/j.mcn.2005.02.006openalex-snapshot

Multiple mechanisms mediate cholesterol-induced synaptogenesis in a CNS neuron

inferredcites →https://doi.org/10.1016/j.nbd.2009.07.031openalex-snapshot

The blood–brain barrier and immune function and dysfunction

inferredcites →https://doi.org/10.1016/j.neubiorev.2010.04.010openalex-snapshot

The effects of cholesterol on learning and memory

inferredcites →https://doi.org/10.1016/j.neulet.2011.03.025openalex-snapshot

Whole body cholesterol metabolism is impaired in Huntington's disease

inferredcites →https://doi.org/10.1016/j.neulet.2011.04.075openalex-snapshot

Corrigendum to “Whole body cholesterol metabolism is impaired in Huntington's disease” [Neurosci. Lett. 494 (2011) 245–249]

inferredcites →https://doi.org/10.1016/j.neurobiolaging.2006.06.026openalex-snapshot

Expression and p75 neurotrophin receptor dependence of cholesterol synthetic enzymes in adult mouse brain

inferredcites →https://doi.org/10.1016/j.neuron.2005.01.040openalex-snapshot

Intraneuronal Aβ Causes the Onset of Early Alzheimer’s Disease-Related Cognitive Deficits in Transgenic Mice

inferredcites →https://doi.org/10.1016/j.neuron.2007.08.008openalex-snapshot

Amyloid Precursor Protein Regulates Brain Apolipoprotein E and Cholesterol Metabolism through Lipoprotein Receptor LRP1

inferredcites →https://doi.org/10.1016/j.neuron.2008.01.003openalex-snapshot

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

inferredcites →https://doi.org/10.1016/j.neuron.2008.04.010openalex-snapshot

ApoE Promotes the Proteolytic Degradation of Aβ

inferredcites →https://doi.org/10.1016/j.neuropharm.2008.02.019openalex-snapshot

Lipid rafts, cholesterol, and the brain

inferredcites →https://doi.org/10.1016/j.neuroscience.2008.06.022openalex-snapshot

Clusterin expression during fetal and postnatal CNS development in mouse

inferredcites →https://doi.org/10.1016/j.physbeh.2004.06.009openalex-snapshot

Hypercholesterolemic diet applied to rat dams protects their offspring against cognitive deficits. Simulated neonatal anoxia model

inferredcites →https://doi.org/10.1016/j.steroids.2004.03.012openalex-snapshot

High doses of simvastatin, pravastatin, and cholesterol reduce brain cholesterol synthesis in guinea pigs

inferredcites →https://doi.org/10.1016/j.tibs.2006.06.008openalex-snapshot

Apolipoprotein E structure: insights into function

inferredcites →https://doi.org/10.1016/j.tips.2008.08.004openalex-snapshot

Mechanisms of microglia accumulation in Alzheimer’s disease: therapeutic implications

inferredcites →https://doi.org/10.1016/s0002-9343(00)00353-3openalex-snapshot

Effects of lovastatin on cognitive function and psychological well-being

inferredcites →https://doi.org/10.1016/s0002-9440(10)65305-9openalex-snapshot

Specific Regional Transcription of Apolipoprotein E in Human Brain Neurons

inferredcites →https://doi.org/10.1016/s0021-9150(97)00280-3openalex-snapshot

Lipid-free apolipoprotein (apo) A-I is converted into alpha-migrating high density lipoproteins by lipoprotein-depleted plasma of normolipidemic donors and apo A-I-deficient patients but not of Tangier disease patients

inferredcites →https://doi.org/10.1016/s0021-9258(17)31529-6openalex-snapshot

Isoform-specific binding of apolipoprotein E to beta-amyloid.

inferredcites →https://doi.org/10.1016/s0021-9258(18)47945-8openalex-snapshot

Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

inferredcites →https://doi.org/10.1016/s0021-9258(18)72197-2openalex-snapshot

THE BIOLOGICAL CONVERSION OF CHOLESTEROL TO CHOLIC ACID

inferredcites →https://doi.org/10.1016/s0021-9258(18)73186-4openalex-snapshot

A STUDY OF THE SYNTHESIS AND DEPOSITION OF LIPIDS IN BRAIN AND OTHER TISSUES WITH DEUTERIUM AS AN INDICATOR

inferredcites →https://doi.org/10.1016/s0022-2275(20)32188-xopenalex-snapshot

Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation

inferredcites →https://doi.org/10.1016/s0022-2275(20)37239-4openalex-snapshot

Sources of cholesterol during development of the rat fetus and fetal organs

inferredcites →https://doi.org/10.1016/s0022-2275(20)37560-xopenalex-snapshot

Brain does not utilize low density lipoprotein-cholesterol during fetal and neonatal development in the sheep

inferredcites →https://doi.org/10.1016/s0022-2275(20)41390-2openalex-snapshot

Effects of apolipoprotein E, beta-very low density lipoproteins, and cholesterol on the extension of neurites by rabbit dorsal root ganglion neurons in vitro.

inferredcites →https://doi.org/10.1016/s0022-3565(25)39496-6openalex-snapshot

Transport mechanism of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors at the blood-brain barrier.

inferredcites →https://doi.org/10.1016/s0039-128x(02)00044-2openalex-snapshot

Steroid and sterol 7-hydroxylation: ancient pathways

inferredcites →https://doi.org/10.1016/s0140-6736(10)61350-5openalex-snapshot

Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials

inferredcites →https://doi.org/10.1016/s0197-4580(96)00076-0openalex-snapshot

The lipid compositions of different regions of rat brain during development and aging

inferredcites →https://doi.org/10.1016/s0304-4157(98)00019-7openalex-snapshot

The differential miscibility of lipids as the basis for the formation of functional membrane rafts

inferredcites →https://doi.org/10.1016/s0306-4522(97)00598-8openalex-snapshot

Behavioural, physiological and morphological analysis of a line of apolipoprotein E knockout mouse

inferredcites →https://doi.org/10.1016/s0896-6273(03)00850-xopenalex-snapshot

ApoE and Clusterin Cooperatively Suppress Aβ Levels and Deposition

inferredcites →https://doi.org/10.1016/s1388-1981(00)00070-6openalex-snapshot

Formation of oxysterols from different pools of cholesterol as studied by stable isotope technique: cerebral origin of most circulating 24S-hydroxycholesterol in rats, but not in mice

inferredcites →https://doi.org/10.1017/s146239941100189xopenalex-snapshot

Smith–Lemli–Opitz syndrome

inferredcites →https://doi.org/10.1021/bi00474a025openalex-snapshot

Apolipoprotein J: structure and tissue distribution

inferredcites →https://doi.org/10.1021/bi010135xopenalex-snapshot

Clusterin, a Binding Protein with a Molten Globule-like Region

inferredcites →https://doi.org/10.1021/bi9626362openalex-snapshot

Interaction of Nascent ApoE2, ApoE3, and ApoE4 Isoforms Expressed in Mammalian Cells with Amyloid Peptide β (1−40). Relevance to Alzheimer's Disease

inferredcites →https://doi.org/10.1021/jp065424fopenalex-snapshot

Polyunsaturation in Lipid Membranes: Dynamic Properties and Lateral Pressure Profiles

inferredcites →https://doi.org/10.1023/a:1018975928974openalex-snapshot

In Vivo and in Vitro Blood–Brain Barrier Transport of 3-Hydroxy-3-Methylglutaryl Coenzyme A (HMG-CoA) Reductase Inhibitors

inferredcites →https://doi.org/10.1038/343425a0openalex-snapshot

Regulation of the mevalonate pathway

inferredcites →https://doi.org/10.1038/383728a0openalex-snapshot

An oxysterol signalling pathway mediated by the nuclear receptor LXRα

inferredcites →https://doi.org/10.1038/mp.2012.15openalex-snapshot

High frequency of potentially pathogenic SORL1 mutations in autosomal dominant early-onset Alzheimer disease

inferredcites →https://doi.org/10.1038/nature11087openalex-snapshot

Apolipoprotein E controls cerebrovascular integrity via cyclophilin A

inferredcites →https://doi.org/10.1038/ncb1819openalex-snapshot

SRF and myocardin regulate LRP-mediated amyloid-β clearance in brain vascular cells

inferredcites →https://doi.org/10.1038/ng0297-123openalex-snapshot

Cholesterol, hedgehog and embryogenesis

inferredcites →https://doi.org/10.1038/ng1196-357openalex-snapshot

Mutations in the human Sonic Hedgehog gene cause holoprosencephaly

inferredcites →https://doi.org/10.1038/ng1197-263openalex-snapshot

Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition

inferredcites →https://doi.org/10.1038/ng2063openalex-snapshot

Mutations in LRP2, which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculo-acoustico-renal syndromes

inferredcites →https://doi.org/10.1038/nm1058openalex-snapshot

Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-β peptides

inferredcites →https://doi.org/10.1038/nn1426openalex-snapshot

High cholesterol level is essential for myelin membrane growth

inferredcites →https://doi.org/10.1038/nrg2984openalex-snapshot

Mechanisms and functions of Hedgehog signalling across the metazoa

inferredcites →https://doi.org/10.1038/nrn2009openalex-snapshot

Reelin, lipoprotein receptors and synaptic plasticity

inferredcites →https://doi.org/10.1038/nrn3012openalex-snapshot

Linking lipids to Alzheimer's disease: cholesterol and beyond

inferredcites →https://doi.org/10.1038/sj.jcbfm.9600419openalex-snapshot

Transport Pathways for Clearance of Human Alzheimer's Amyloid β-Peptide and Apolipoproteins E and J in the Mouse Central Nervous System

inferredcites →https://doi.org/10.1046/j.1469-1809.2003.00034.xopenalex-snapshot

Smith‐Lemli‐Opitz Syndrome and the DHCR7 Gene

inferredcites →https://doi.org/10.1046/j.1471-4159.1995.64020895.xopenalex-snapshot

Cholesterol for Synthesis of Myelin Is Made Locally, Not Imported into Brain

inferredcites →https://doi.org/10.1046/j.1471-4159.1998.70052070.xopenalex-snapshot

Nascent Astrocyte Particles Differ from Lipoproteins in CSF

inferredcites →https://doi.org/10.1046/j.1471-4159.2001.00015.xopenalex-snapshot

Parameters related to lipid metabolism as markers of myelination in mouse brain

inferredcites →https://doi.org/10.1056/nejm199908123410707openalex-snapshot

Drug Treatment of Lipid Disorders

inferredcites →https://doi.org/10.1073/pnas.0508693102openalex-snapshot

Apolipoprotein (apo) E4 enhances amyloid β peptide production in cultured neuronal cells: ApoE structure as a potential therapeutic target

inferredcites →https://doi.org/10.1073/pnas.0600549103openalex-snapshot

Apolipoprotein E4: A causative factor and therapeutic target in neuropathology, including Alzheimer’s disease

inferredcites →https://doi.org/10.1073/pnas.0710010105openalex-snapshot

Mutations in the very low-density lipoprotein receptor VLDLR cause cerebellar hypoplasia and quadrupedal locomotion in humans

inferredcites →https://doi.org/10.1073/pnas.0908176106openalex-snapshot

Reelin signaling antagonizes β-amyloid at the synapse

inferredcites →https://doi.org/10.1073/pnas.1207022109openalex-snapshot

Structural differences between apoE3 and apoE4 may be useful in developing therapeutic agents for Alzheimer’s disease

inferredcites →https://doi.org/10.1073/pnas.172510899openalex-snapshot

Liver X receptors in the central nervous system: From lipid homeostasis to neuronal degeneration

inferredcites →https://doi.org/10.1073/pnas.83.4.1125openalex-snapshot

Expression of apolipoprotein E during nerve degeneration and regeneration.

inferredcites →https://doi.org/10.1073/pnas.90.20.9649openalex-snapshot

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.

inferredcites →https://doi.org/10.1073/pnas.90.5.1977openalex-snapshot

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

inferredcites →https://doi.org/10.1073/pnas.93.16.8460openalex-snapshot

Defective forebrain development in mice lacking gp330/megalin.

inferredcites →https://doi.org/10.1073/pnas.93.18.9799openalex-snapshot

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation.

inferredcites →https://doi.org/10.1073/pnas.95.11.6460openalex-snapshot

Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons

inferredcites →https://doi.org/10.1073/pnas.95.15.8686openalex-snapshot

Knockout of the abetalipoproteinemia gene in mice: Reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes

inferredcites →https://doi.org/10.1073/pnas.96.13.7238openalex-snapshot

cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain

inferredcites →https://doi.org/10.1074/jbc.270.45.27063openalex-snapshot

Stable Expression and Secretion of Apolipoproteins E3 and E4 in Mouse Neuroblastoma Cells Produces Differential Effects on Neurite Outgrowth

inferredcites →https://doi.org/10.1074/jbc.272.49.30766openalex-snapshot

Role of Lipoproteins in the Delivery of Lipids to Axons during Axonal Regeneration

inferredcites →https://doi.org/10.1074/jbc.272.6.3137openalex-snapshot

Activation of the Nuclear Receptor LXR by Oxysterols Defines a New Hormone Response Pathway

inferredcites →https://doi.org/10.1074/jbc.274.21.14624openalex-snapshot

Cholesterol Biosynthesis from Lanosterol

inferredcites →https://doi.org/10.1074/jbc.m104776200openalex-snapshot

Effect of the Structure of Natural Sterols and Sphingolipids on the Formation of Ordered Sphingolipid/Sterol Domains (Rafts)

inferredcites →https://doi.org/10.1074/jbc.m110.151084openalex-snapshot

Apolipoprotein E4 Domain Interaction Mediates Detrimental Effects on Mitochondria and Is a Potential Therapeutic Target for Alzheimer Disease

inferredcites →https://doi.org/10.1074/jbc.m303415200openalex-snapshot

Knockout of the Cholesterol 24-Hydroxylase Gene in Mice Reveals a Brain-specific Mechanism of Cholesterol Turnover

inferredcites →https://doi.org/10.1074/jbc.m306923200openalex-snapshot

APOE Genotype and an ApoE-mimetic Peptide Modify the Systemic and Central Nervous System Inflammatory Response

inferredcites →https://doi.org/10.1074/jbc.m309475200openalex-snapshot

Astroglial Regulation of Apolipoprotein E Expression in Neuronal Cells

inferredcites →https://doi.org/10.1074/jbc.m402324200openalex-snapshot

Differential Expression of Cholesterol Hydroxylases in Alzheimer's Disease

inferredcites →https://doi.org/10.1074/jbc.m407963200openalex-snapshot

ABCA1 Is Required for Normal Central Nervous System ApoE Levels and for Lipidation of Astrocyte-secreted apoE

inferredcites →https://doi.org/10.1074/jbc.m413895200openalex-snapshot

Statins Cause Intracellular Accumulation of Amyloid Precursor Protein, β-Secretase-cleaved Fragments, and Amyloid β-Peptide via an Isoprenoid-dependent Mechanism

inferredcites →https://doi.org/10.1074/jbc.m508781200openalex-snapshot

The Absence of ABCA1 Decreases Soluble ApoE Levels but Does Not Diminish Amyloid Deposition in Two Murine Models of Alzheimer Disease

inferredcites →https://doi.org/10.1074/jbc.m509164200openalex-snapshot

Cholesterol-mediated Neurite Outgrowth Is Differently Regulated between Cortical and Hippocampal Neurons

inferredcites →https://doi.org/10.1074/jbc.m509530200openalex-snapshot

Significance of Sterol Structural Specificity

inferredcites →https://doi.org/10.1074/jbc.m510851200openalex-snapshot

Model of Biologically Active Apolipoprotein E Bound to Dipalmitoylphosphatidylcholine

inferredcites →https://doi.org/10.1074/jbc.m808482200openalex-snapshot

Peroxisome Proliferator-activated Receptor γ Stimulation of Adipocyte ApoE Gene Transcription Mediated by the Liver Receptor X Pathway

inferredcites →https://doi.org/10.1074/jbc.m901012200openalex-snapshot

A Unified Scheme for Initiation and Conformational Adaptation of Human Apolipoprotein E N-terminal Domain upon Lipoprotein Binding and for Receptor Binding Activity

inferredcites →https://doi.org/10.1074/jbc.r100057200openalex-snapshot

Control of Cholesterol Turnover in the Mouse

inferredcites →https://doi.org/10.1074/jbc.r800009200openalex-snapshot

Understanding the Association of Apolipoprotein E4 with Alzheimer Disease: Clues from Its Structure

inferredcites →https://doi.org/10.1080/02713680701231857openalex-snapshot

Cholesterol-24S-hydroxylase (CYP46A1) Is Specifically Expressed in Neurons of the Neural Retina

inferredcites →https://doi.org/10.1083/jcb.126.2.465openalex-snapshot

Upregulation of the low density lipoprotein receptor at the blood-brain barrier: intercommunications between brain capillary endothelial cells and astrocytes.

inferredcites →https://doi.org/10.1083/jcb.200207113openalex-snapshot

Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts

inferredcites →https://doi.org/10.1083/jcb.200404149openalex-snapshot

Neuronal membrane cholesterol loss enhances amyloid peptide generation

inferredcites →https://doi.org/10.1083/jcb.200410090openalex-snapshot

A lipid boundary separates APP and secretases and limits amyloid β-peptide generation

inferredcites →https://doi.org/10.1086/444400openalex-snapshot

Homozygous Deletion of the Very Low Density Lipoprotein Receptor Gene Causes Autosomal Recessive Cerebellar Hypoplasia with Cerebral Gyral Simplification

inferredcites →https://doi.org/10.1093/hmg/11.17.1953openalex-snapshot

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

inferredcites →https://doi.org/10.1093/hmg/ddm170openalex-snapshot

Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation

inferredcites →https://doi.org/10.1093/hmg/ddu539openalex-snapshot

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

inferredcites →https://doi.org/10.1093/jn/129.2.451sopenalex-snapshot

Insights into Apolipoprotein B Biology from Transgenic and Gene-Targeted Mice

inferredcites →https://doi.org/10.1093/jn/129.2.473sopenalex-snapshot

The LDL Receptor Gene Family, Apolipoprotein B and Cholesterol in Embryonic Development

inferredcites →https://doi.org/10.1093/jnen/59.12.1106openalex-snapshot

Cholesterol Is Sequestered in the Brains of Mice with Niemann-Pick Type C Disease but Turnover Is Increased

inferredcites →https://doi.org/10.1097/00005344-199302000-00022openalex-snapshot

Comparison of Fluvastatin and Lovastatin Blood-Brain Barrier Transfer Using In Vitro and In Vivo Methods

inferredcites →https://doi.org/10.1097/00041433-200104000-00003openalex-snapshot

Cholesterol metabolism in the brain

inferredcites →https://doi.org/10.1097/00041433-200106000-00010openalex-snapshot

The origins and roles of cholesterol and fatty acids in the fetus

inferredcites →https://doi.org/10.1097/ccm.0b013e3182227e4aopenalex-snapshot

Simvastatin in traumatic brain injury: Effect on brain edema mechanisms

inferredcites →https://doi.org/10.1097/mol.0b013e32832d3a10openalex-snapshot

Apolipoprotein E receptors in the nervous system

inferredcites →https://doi.org/10.1097/wad.0b013e3181d61feaopenalex-snapshot

Effects of Simvastatin on Cholesterol Metabolism and Alzheimer Disease Biomarkers

inferredcites →https://doi.org/10.1101/cshperspect.a006312openalex-snapshot

Apolipoprotein E and Apolipoprotein E Receptors: Normal Biology and Roles in Alzheimer Disease

inferredcites →https://doi.org/10.1101/gad.180885.111openalex-snapshot

Structural basis of agrin–LRP4–MuSK signaling

inferredcites →https://doi.org/10.1111/j.1399-0004.2005.00515.xopenalex-snapshot

Recent insights into the Smith–Lemli–Opitz syndrome

inferredcites →https://doi.org/10.1111/j.1432-1033.1989.tb14773.xopenalex-snapshot

Gangliosides in normal human serum

inferredcites →https://doi.org/10.1111/j.1471-4159.2006.03763.xopenalex-snapshot

The 3‐hydroxy‐3‐methylglutaryl co‐enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons

inferredcites →https://doi.org/10.1111/j.1471-4159.2011.07474.xopenalex-snapshot

Inhibition of neuronal cholesterol biosynthesis with lovastatin leads to impaired synaptic vesicle release even in the presence of lipoproteins or geranylgeraniol

inferredcites →https://doi.org/10.1111/j.1471-4159.2012.07893.xopenalex-snapshot

Cholesterol metabolism is associated with soluble amyloid precursor protein production in Alzheimer's disease

inferredcites →https://doi.org/10.1111/j.1600-0404.2006.00684.xopenalex-snapshot

Oxysterols and Alzheimer's disease

inferredcites →https://doi.org/10.1111/j.1747-4949.2008.00200.xopenalex-snapshot

The Neuroprotection with Statin Therapy for Acute Recovery Trial (Neustart): An Adaptive Design Phase I Dose-Escalation Study of High-Dose Lovastatin in Acute Ischemic Stroke

inferredcites →https://doi.org/10.1124/dmd.30.11.1158openalex-snapshot

Liver-Specific Distribution of Rosuvastatin in Rats: Comparison with Pravastatin and Simvastatin

inferredcites →https://doi.org/10.1124/jpet.105.094136openalex-snapshot

Brain Cholesterol Synthesis in Mice Is Affected by High Dose of Simvastatin but Not of Pravastatin

inferredcites →https://doi.org/10.1126/science.1206936openalex-snapshot

The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence

inferredcites →https://doi.org/10.1126/science.1217697openalex-snapshot

ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models

inferredcites →https://doi.org/10.1126/science.1220725openalex-snapshot

Old Drug, New Hope for Alzheimer's Disease

inferredcites →https://doi.org/10.1126/science.2063194openalex-snapshot

Three-Dimensional Structure of the LDL Receptor-Binding Domain of Human Apolipoprotein E

inferredcites →https://doi.org/10.1126/science.294.5548.1866openalex-snapshot

Nuclear Receptors and Lipid Physiology: Opening the X-Files

inferredcites →https://doi.org/10.1126/science.3283935openalex-snapshot

Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology

inferredcites →https://doi.org/10.1126/science.3576212openalex-snapshot

Lipoprotein Uptake by Neuronal Growth Cones in Vitro

inferredcites →https://doi.org/10.1126/science.8346443openalex-snapshot

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

inferredcites →https://doi.org/10.1128/mcb.25.21.9259-9268.2005openalex-snapshot

F-Spondin Interaction with the Apolipoprotein E Receptor ApoEr2 Affects Processing of Amyloid Precursor Protein

inferredcites →https://doi.org/10.1136/jnnp.2008.150433openalex-snapshot

Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study

inferredcites →https://doi.org/10.1146/annurev.biochem.71.110601.135342openalex-snapshot

Lipoprotein Receptors in the Nervous System

inferredcites →https://doi.org/10.1155/2008/780452openalex-snapshot

Peroxisome Proliferator‐Activated Receptor β/δ in the Brain: Facts and Hypothesis

inferredcites →https://doi.org/10.1155/2010/219683openalex-snapshot

Diet and Age Interactions with Regards to Cholesterol Regulation and Brain Pathogenesis

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Pharmacokinetic Dose-Scheduling Study of Hedgehog Pathway Inhibitor Vismodegib (GDC-0449) in Patients with Locally Advanced or Metastatic Solid Tumors

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Long-Term Statin Therapy and CSF Cholesterol Levels: Implications for Alzheimer’s Disease

inferredcites →https://doi.org/10.1159/000334534openalex-snapshot

Dual Effects of Statins on Aβ Metabolism: Upregulation of the Degradation of APP-CTF and Aβ Clearance

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Prevalence of Apolipoprotein E4 Genotype and Homozygotes (APOE e4/4) among Patients Diagnosed with Alzheimer’s Disease: A Systematic Review and Meta-Analysis

inferredcites →https://doi.org/10.1159/000334914openalex-snapshot

APOE-Mimetic Peptides Reduce Behavioral Deficits, Plaques and Tangles in Alzheimer’s Disease Transgenics

inferredcites →https://doi.org/10.1161/01.atv.0000013312.32196.49openalex-snapshot

Oxysterols

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Brain Cholesterol: Long Secret Life Behind a Barrier

inferredcites →https://doi.org/10.1161/01.atv.19.5.1306openalex-snapshot

Effects of a Frequent Apolipoprotein E Isoform, ApoE4 Freiburg (Leu28→Pro), on Lipoproteins and the Prevalence of Coronary Artery Disease in Whites

inferredcites →https://doi.org/10.1172/jci104631openalex-snapshot

BODY CHOLESTEROL METABOLISM IN MAN. I. THE EQUILIBRATION OF SERUM AND TISSUE CHOLESTEROL*†

inferredcites →https://doi.org/10.1172/jci10498openalex-snapshot

Clearance of Alzheimer’s amyloid-β1-40 peptide from brain by LDL receptor–related protein-1 at the blood-brain barrier

inferredcites →https://doi.org/10.1172/jci106277openalex-snapshot

The measurement of the exchangeable pools of cholesterol in the baboon

inferredcites →https://doi.org/10.1172/jci111044openalex-snapshot

Lipoprotein receptors in the liver. Control signals for plasma cholesterol traffic.

inferredcites →https://doi.org/10.1172/jci115288openalex-snapshot

Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation.

inferredcites →https://doi.org/10.1172/jci117407openalex-snapshot

Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3.

inferredcites →https://doi.org/10.1172/jci12103openalex-snapshot

7-Dehydrocholesterol–dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome

inferredcites →https://doi.org/10.1172/jci16388openalex-snapshot

Do oxysterols control cholesterol homeostasis?

inferredcites →https://doi.org/10.1172/jci200112103openalex-snapshot

7-Dehydrocholesterol–dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome

inferredcites →https://doi.org/10.1172/jci200216388openalex-snapshot

Do oxysterols control cholesterol homeostasis?

inferredcites →https://doi.org/10.1177/0883073809332696openalex-snapshot

Mutations in VLDLR as a Cause for Autosomal Recessive Cerebellar Ataxia With Mental Retardation (Dysequilibrium Syndrome)

inferredcites →https://doi.org/10.1179/147683009x423328openalex-snapshot

No association between cognitive achievements, academic performance and serum cholesterol concentrations among school-aged children

showing the first 200 of 234 · page through all 234

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Normal IQ is possible in Smith‐Lemli‐Opitz syndrome

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Molecular markers of brain cholesterol homeostasis are unchanged despite a smaller brain mass in a mouse model of cholesteryl ester storage disease

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Ouabain Modulates the Lipid Composition of Hippocampal Plasma Membranes from Rats with LPS-induced Neuroinflammation

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AMFR dysfunction causes autosomal recessive spastic paraplegia in human that is amenable to statin treatment in a preclinical model

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TDP-43 dysregulation impairs cholesterol metabolism linked with myelination defects

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LAMP2 as a marker of EBV-mediated B lymphocyte transformation in the study of lysosomal storage diseases

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The Cholesterol-Lowering Effects of Probiotic Bacteria on Lipid Metabolism

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Dendritic spine membrane proteome and its alterations in autistic spectrum disorder

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Modulation of cholesterol metabolism with Phytoremedies in Alzheimer’s disease: A comprehensive review

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Membrane cholesterol depletion in cortical neurons highlights altered NMDA receptor functionality in a mouse model of amyotrophic lateral sclerosis

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The impairment of cholesterol metabolism in Huntington disease

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Implications of cerebrovascular ATP-binding cassette transporter G1 (ABCG1) and apolipoprotein M in cholesterol transport at the blood-brain barrier

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Influence of 7α-hydroxycholesterol on sphingomyelin and sphingomyelin/phosphatidylcholine films - The Langmuir monolayer study complemented with theoretical calculations

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DHCR7 links cholesterol synthesis with neuronal development and axonal integrity

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Statin-induced increase in actin polymerization modulates GPCR dynamics and compartmentalization

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Suppression of brain cholesterol synthesis in male Mecp2-deficient mice is age dependent and not accompanied by a concurrent change in the rate of fatty acid synthesis

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Effects of DHA (omega-3 fatty acid) and estradiol on amyloid β-peptide regulation in the brain

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Lipid metabolism in Alzheimer’s disease

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Epileptic activity during early postnatal life in the AY-9944 model of atypical absence epilepsy

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Simvastatin markedly alters locomotor behavior parameters and induces mortality in planarians

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Alteration of serum lipid profile, SRB1 loss, and impaired Nrf2 activation in CDKL5 disorder

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Comparative alteration in atherogenic indices and hypocholesteremic effect of palm oil and palm oil mill effluent in normal albino rats

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Transcriptional analysis of glial cell differentiation in the postnatal murine spinal cord

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Effect of itraconazole on mouse mesencephalic neurons

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Microarray gene expression analysis reveals major differences between Toxocara canis and Toxocara cati neurotoxocarosis and involvement of T. canis in lipid biosynthetic processes

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Effect of Brain Tumor Presence During Radiation on Tissue Toxicity: Transcriptomic and Metabolic Changes

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Depression and serum low-density lipoprotein: A systematic review and meta-analysis

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Advances in statin adverse reactions and the potential mechanisms: A systematic review

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Bile Acids in Hepatic Encephalopathy

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Apolipoprotein B gene expression and regulation in relation to Alzheimer’s disease pathophysiology

inferred← citeshttps://doi.org/10.1016/j.jlr.2025.100865openalex-snapshot

Cerebrospinal fluid lipoprotein-mediated cholesterol delivery to neurons is impaired in Alzheimer's disease and involves APOE4

inferred← citeshttps://doi.org/10.1016/j.jlr.2025.100868openalex-snapshot

Oxysterol-binding protein ORP6 regulates lipid metabolism and brain Aβ production

inferred← citeshttps://doi.org/10.1016/j.jns.2014.10.020openalex-snapshot

Vascular comorbidities in the onset and progression of multiple sclerosis

inferred← citeshttps://doi.org/10.1016/j.jpsychores.2022.110763openalex-snapshot

Elevated atherogenic lipid profile in youth with bipolar disorder during euthymia and hypomanic/mixed but not depressive states

inferred← citeshttps://doi.org/10.1016/j.livres.2022.11.005openalex-snapshot

The contributions of bacteria metabolites to the development of hepatic encephalopathy

inferred← citeshttps://doi.org/10.1016/j.mcn.2017.11.006openalex-snapshot

A proteomic investigation into mechanisms underpinning corticosteroid effects on neural stem cells

inferred← citeshttps://doi.org/10.1016/j.metabol.2016.01.015openalex-snapshot

Obesity development in neuron-specific lipoprotein lipase deficient mice is not responsive to increased dietary fat content or change in fat composition

inferred← citeshttps://doi.org/10.1016/j.nbd.2016.02.017openalex-snapshot

Altered cholesterol biosynthesis causes precocious neurogenesis in the developing mouse forebrain

inferred← citeshttps://doi.org/10.1016/j.nbd.2019.104635openalex-snapshot

Pathogenesis of SCA3 and implications for other polyglutamine diseases

inferred← citeshttps://doi.org/10.1016/j.neuint.2023.105635openalex-snapshot

Brain cholesterol homeostasis and its association with neurodegenerative diseases

inferred← citeshttps://doi.org/10.1016/j.neulet.2018.02.059openalex-snapshot

Relationship between the hippocampal expression of selected cytochrome P450 isoforms and the animal performance in the hippocampus-dependent learning task

inferred← citeshttps://doi.org/10.1016/j.neurobiolaging.2016.05.017openalex-snapshot

Perturbed cholesterol homeostasis in aging spinal cord

inferred← citeshttps://doi.org/10.1016/j.neuropharm.2018.01.039openalex-snapshot

Membrane cholesterol removal and replenishment affect rat and monkey brain monoamine transporters

inferred← citeshttps://doi.org/10.1016/j.neuropharm.2020.108242openalex-snapshot

Cholesterol regulates cannabinoid analgesia through glycine receptors

inferred← citeshttps://doi.org/10.1016/j.neuropharm.2026.111078openalex-snapshot

Disruption of dopamine transmission by cholesterol depletion is associated with alterations in protein lipid raft partitioning and actin dynamics

inferred← citeshttps://doi.org/10.1016/j.nut.2014.10.017openalex-snapshot

Cholesterol overload impairing cerebellar function: The promise of natural products

inferred← citeshttps://doi.org/10.1016/j.ortho.2019.03.020openalex-snapshot

The Smith–Lemli–Opitz syndrome and dentofacial anomalies diagnostic: Case reports and literature review

inferred← citeshttps://doi.org/10.1016/j.pcad.2023.02.007openalex-snapshot

PCSK9 inhibitor, ezetimibe, and bempedoic acid: Evidence-based therapies for statin-intolerant patients

inferred← citeshttps://doi.org/10.1016/j.pharep.2017.04.018openalex-snapshot

Possible anti-depressant effect of efavirenz and pro-depressive-like effect of voriconazole in specified doses in various experimental models of depression in mice

inferred← citeshttps://doi.org/10.1016/j.physbeh.2016.02.029openalex-snapshot

The effect of prolonged simvastatin application on serotonin uptake, membrane microviscosity and behavioral changes in the animal model

inferred← citeshttps://doi.org/10.1016/j.pneurobio.2015.10.005openalex-snapshot

Alternative mitochondrial electron transfer for the treatment of neurodegenerative diseases and cancers: Methylene blue connects the dots

inferred← citeshttps://doi.org/10.1016/j.pscychresns.2018.10.001openalex-snapshot

Association between olanzapine treatment and brain cortical thickness and gray/white matter contrast is moderated by cholesterol in psychotic disorders

inferred← citeshttps://doi.org/10.1016/j.reprotox.2016.07.006openalex-snapshot

Chromium VI − Induced developmental toxicity of placenta is mediated through spatiotemporal dysregulation of cell survival and apoptotic proteins

inferred← citeshttps://doi.org/10.1016/j.rpsm.2023.03.002openalex-snapshot

Biomarkers as proxies for cognitive reserve: The role of high density lipoprotein cholesterol in first episode of psychosis

inferred← citeshttps://doi.org/10.1016/j.scitotenv.2021.147434openalex-snapshot

Meta-transcriptomic profiling of functional variation of freshwater microbial communities induced by an antidepressant sertraline hydrochloride

inferred← citeshttps://doi.org/10.1016/j.semcdb.2020.08.004openalex-snapshot

Lipid profiling of brain tissue and blood after traumatic brain injury

inferred← citeshttps://doi.org/10.1016/j.snb.2016.08.169openalex-snapshot

Cytocompatible peroxidase mimic CuO:graphene nanosphere composite as colorimetric dual sensor for hydrogen peroxide and cholesterol with its logic gate implementation

inferred← citeshttps://doi.org/10.1016/j.tox.2020.152381openalex-snapshot

Glutamate affects cholesterol homeostasis within the brain via the up-regulation of CYP46A1 and ApoE

inferred← citeshttps://doi.org/10.1016/j.yfrne.2014.08.005openalex-snapshot

Regulation of local steroidogenesis in the brain and in prostate cancer: Lessons learned from interdisciplinary collaboration

inferred← citeshttps://doi.org/10.1016/j.ymgmr.2015.07.006openalex-snapshot

Delivery of the 7-dehydrocholesterol reductase gene to the central nervous system using adeno-associated virus vector in a mouse model of Smith-Lemli-Opitz Syndrome

inferred← citeshttps://doi.org/10.1016/j.ynstr.2022.100476openalex-snapshot

Labelfree mapping and profiling of altered lipid homeostasis in the rat hippocampus after traumatic stress: Role of oxidative homeostasis

inferred← citeshttps://doi.org/10.1017/s0043933917000575openalex-snapshot

Egg intake and serum low density lipoprotein cholesterol in humans

inferred← citeshttps://doi.org/10.1021/acs.jpcb.5c06652openalex-snapshot

Cholesterol-Dependent Conformational Modulation and Binding Hotspots of P2RX7: Insights from Molecular Dynamics Simulations and Structural Analyses

inferred← citeshttps://doi.org/10.1021/acschemneuro.9b00581openalex-snapshot

Efficacy of Cholesterol Nose-to-Brain Delivery for Brain Targeting in Huntington’s Disease

inferred← citeshttps://doi.org/10.1021/acsmedchemlett.5c00740openalex-snapshot

Radiosynthesis and Evaluation of 18 F-Labeled Deuterated Radioligand for Positron Emission Tomography Imaging of Cholesterol 24-Hydroxylase

inferred← citeshttps://doi.org/10.1021/jasms.2c00271openalex-snapshot

Pyrylium-Based Derivatization for Rapid Labeling and Enhanced Detection of Cholesterol in Mass Spectrometry Imaging

inferred← citeshttps://doi.org/10.1038/nrd4280openalex-snapshot

Liver X receptors in lipid metabolism: opportunities for drug discovery

inferred← citeshttps://doi.org/10.1038/pr.2015.33openalex-snapshot

Altered lipid subfraction profile and impaired antioxidant defense of high-density lipoprotein in Smith-Lemli-Opitz syndrome

inferred← citeshttps://doi.org/10.1038/s41380-023-02060-9openalex-snapshot

Neuroimaging genetics approaches to identify new biomarkers for the early diagnosis of autism spectrum disorder

inferred← citeshttps://doi.org/10.1038/s41380-026-03682-5openalex-snapshot

NTPDase2 suppresses hippocampal astrocyte-supplied cholesterol through hydrolyzing eATP in depression

inferred← citeshttps://doi.org/10.1038/s41419-025-07993-3openalex-snapshot

Cut the fat: targeting cholesterol and lipid metabolism in glioblastoma

inferred← citeshttps://doi.org/10.1038/s41531-021-00206-6openalex-snapshot

Serum lipid profile among sporadic and familial forms of Parkinson’s disease

inferred← citeshttps://doi.org/10.1038/s41583-025-00908-3openalex-snapshot

Lipid metabolism, remodelling and intercellular transfer in the CNS

inferred← citeshttps://doi.org/10.1038/s41598-017-02638-8openalex-snapshot

Expression profiles of cholesterol metabolism-related genes are altered during development of experimental autoimmune encephalomyelitis in the rat spinal cord

inferred← citeshttps://doi.org/10.1038/s41598-017-13933-9openalex-snapshot

Cellular hormetic response to 27-hydroxycholesterol promotes neuroprotection through AICD induction of MAST4 abundance and kinase activity

inferred← citeshttps://doi.org/10.1038/s41598-017-16780-wopenalex-snapshot

Preferential selection of Arginine at the lipid-water-interface of TRPV1 during vertebrate evolution correlates with its snorkeling behaviour and cholesterol interaction

inferred← citeshttps://doi.org/10.1038/s41598-017-17402-1openalex-snapshot

Bis(monoacylglycero)phosphate lipids in the retinal pigment epithelium implicate lysosomal/endosomal dysfunction in a model of Stargardt disease and human retinas

inferred← citeshttps://doi.org/10.1038/s41598-018-20965-2openalex-snapshot

Structural properties of apolipoprotein A-I mimetic peptides that promote ABCA1-dependent cholesterol efflux

inferred← citeshttps://doi.org/10.1038/s41598-019-51865-8openalex-snapshot

LXRβ controls glioblastoma cell growth, lipid balance, and immune modulation independently of ABCA1

inferred← citeshttps://doi.org/10.1038/srep32797openalex-snapshot

Food-induced changes of lipids in rat neuronal tissue visualized by ToF-SIMS imaging

inferred← citeshttps://doi.org/10.1039/d3ay01114copenalex-snapshot

Proteomic analysis of exosomes derived from human mature milk and colostrum of mothers with term, late preterm, or very preterm delivery

inferred← citeshttps://doi.org/10.1042/ns20210008openalex-snapshot

Oligodendrocytes in the aging brain

inferred← citeshttps://doi.org/10.1080/01616412.2020.1724463openalex-snapshot

Low density lipoprotein cholesterol values and outcome of stroke patients: influence of previous aspirin therapy

inferred← citeshttps://doi.org/10.1080/07391102.2023.2201835openalex-snapshot

Paradoxical effect of Aβ on protein levels of ABCA1 in astrocytes, microglia, and neurons isolated from C57BL/6 mice: an in vitro and in silico study to elucidate the effect of Aβ on ABCA1 in the brain cells

inferred← citeshttps://doi.org/10.1080/09712119.2020.1848846openalex-snapshot

Nutritional parameters of eggs from laying hens fed with flaxseed meal or mixture with rapeseed meal or rice bran

inferred← citeshttps://doi.org/10.1080/1028415x.2017.1416942openalex-snapshot

The relationship between cholesterol level and Alzheimer’s disease-associated APP proteolysis/Aβ metabolism

inferred← citeshttps://doi.org/10.1080/10408398.2018.1529653openalex-snapshot

Lipids as biomarkers of brain disorders

inferred← citeshttps://doi.org/10.1080/14728222.2023.2235718openalex-snapshot

The role of the ATP-Binding Cassette A1 (ABCA1) in neurological disorders: a mechanistic review

inferred← citeshttps://doi.org/10.1080/14740338.2020.1796966openalex-snapshot

Statin use and safety concerns: an overview of the past, present, and the future

inferred← citeshttps://doi.org/10.1080/17425255.2020.1828343openalex-snapshot

An update on PCSK9 inhibitors- pharmacokinetics, drug interactions, and toxicity

inferred← citeshttps://doi.org/10.1080/2314808x.2020.1759003openalex-snapshot

Fish-oil supplementation improves retinal injury induced by diabetes and hypercholesterolemia in male Wistar rats

inferred← citeshttps://doi.org/10.1089/neu.2015.4007openalex-snapshot

Nodal versus Total Axonal Strain and the Role of Cholesterol in Traumatic Brain Injury

inferred← citeshttps://doi.org/10.1089/scd.2016.0259openalex-snapshot

Canonical microRNAs Enable Differentiation, Protect Against DNA Damage, and Promote Cholesterol Biosynthesis in Neural Stem Cells

inferred← citeshttps://doi.org/10.1093/abbs/gmu123openalex-snapshot

DAMP, an acidotropic pH indicator, can be used as a tool to visualize non-esterified cholesterol in cells

inferred← citeshttps://doi.org/10.1093/eurheartj/ehaa1080openalex-snapshot

How low is safe? The frontier of very low (<30 mg/dL) LDL cholesterol

inferred← citeshttps://doi.org/10.1093/narcan/zcab009openalex-snapshot

Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma

inferred← citeshttps://doi.org/10.1093/narmme/ugaf009openalex-snapshot

The translational landscape of reactive astrocytes reveals the impact of eIF2B-mediated dysregulation in VWM disease

inferred← citeshttps://doi.org/10.1097/cad.0000000000001533openalex-snapshot

The effects of statin therapy on brain tumors, particularly glioma: a review

inferred← citeshttps://doi.org/10.1097/md.0000000000012884openalex-snapshot

The genetic association between apolipoprotein E gene polymorphism and Parkinson disease

inferred← citeshttps://doi.org/10.1097/poc.0000000000000144openalex-snapshot

Direct-to-Consumer Testing

inferred← citeshttps://doi.org/10.1097/wnr.0000000000001717openalex-snapshot

Identification of the expression of farnesoid X receptor in astrocytes

inferred← citeshttps://doi.org/10.1101/196204openalex-snapshot

The effects of long-term atorvastatin use on the cytoarchitecture of new and older neurons of sensorimotor nucleus HVC in a juvenile songbird model

inferred← citeshttps://doi.org/10.1101/2023.05.05.539444openalex-snapshot

Up-regulation of cholesterol synthesis pathways and limited neurodegeneration in a knock-in Sod1 mutant mouse model of ALS

inferred← citeshttps://doi.org/10.1101/2025.02.25.639888openalex-snapshot

The 16p11.2 microdeletion exacerbates neurodevelopmental alterations induced by early-life microbiome perturbation

inferred← citeshttps://doi.org/10.1101/2025.05.29.656749openalex-snapshot

Sparse Neuronal C4 Elevation Induces Network-Wide Transcriptomic and Lipid-Droplet Remodeling in the Cortical Microenvironment

inferred← citeshttps://doi.org/10.1101/2025.11.24.689041openalex-snapshot

Fus depleted oligodendrocytes reduce neuronal damage and attenuate AD progression in the App NL-G-F mouse

inferred← citeshttps://doi.org/10.1109/tim.2026.3667332openalex-snapshot

Highly Sensitive Cholesterol Detection Using β -Cyclodextrin and Graphene Oxide-Enhanced Surface Plasmon Resonance Sensor

inferred← citeshttps://doi.org/10.1111/ap.12116openalex-snapshot

Statin Use, Ageing, and Cognition: A Review

inferred← citeshttps://doi.org/10.1111/cns.14411openalex-snapshot

The potential role of glucose metabolism, lipid metabolism, and amino acid metabolism in the treatment of Parkinson's disease

inferred← citeshttps://doi.org/10.1111/ejn.14758openalex-snapshot

Obesity and Alzheimer’s disease: Molecular bases

inferred← citeshttps://doi.org/10.1111/ejn.16586openalex-snapshot

Gene expression patterns of the LDL receptor and its inhibitor Pcsk9 in the adult zebrafish brain suggest a possible role in neurogenesis

inferred← citeshttps://doi.org/10.1111/febs.16175openalex-snapshot

Cholesterol dyshomeostasis in amyotrophic lateral sclerosis: cause, consequence, or epiphenomenon?

inferred← citeshttps://doi.org/10.1111/joim.12959openalex-snapshot

Current and emerging avenues for Alzheimer's disease drug targets

inferred← citeshttps://doi.org/10.1134/s0006297923030045openalex-snapshot

Role of Lipids in Regulation of Neuroglial Interactions

inferred← citeshttps://doi.org/10.1134/s0036024417130027openalex-snapshot

Modelling of the Hypothalamic-Pituitary-Adrenal Axis Perturbations by Externally Induced Cholesterol Pulses of Finite Duration and with Asymmetrically Distributed Concentration Profile

inferred← citeshttps://doi.org/10.1134/s1990747824700454openalex-snapshot

Effects of 24-Hydroxycholesterol on the ATP-Induced Trigeminal Nerve Electrical Activity and the Mast Cells Degranulation

inferred← citeshttps://doi.org/10.1134/s2079059715060192openalex-snapshot

Association of dopamine receptor D4 (DRD4) gene polymorphism with cardiovascular disease risk factors

inferred← citeshttps://doi.org/10.1139/cjpp-2014-0125openalex-snapshot

Alteration in the expression ofexon IICtranscripts ofbrain-derived neurotrophic factorgene by simvastain in chronic mild stress in mice: a possible link with dopaminergic pathway

inferred← citeshttps://doi.org/10.1155/2016/2106465openalex-snapshot

Global Mapping of Traditional Chinese Medicine into Bioactivity Space and Pathways Annotation Improves Mechanistic Understanding and Discovers Relationships between Therapeutic Action (Sub)classes

inferred← citeshttps://doi.org/10.1155/2016/7524308openalex-snapshot

Cholesterol Retards Senescence in Bone Marrow Mesenchymal Stem Cells by Modulating Autophagy and ROS/p53/p21Cip1/Waf1 Pathway

inferred← citeshttps://doi.org/10.1155/2018/8598054openalex-snapshot

Safety and Efficacy of Extremely Low LDL-Cholesterol Levels and Its Prospects in Hyperlipidemia Management

inferred← citeshttps://doi.org/10.1155/2022/4812993openalex-snapshot

Amelioration of Age‐Related Multiple Neuronal Impairments and Inflammation in High‐Fat Diet‐Fed Rats: The Prospective Multitargets of Geraniol

inferred← citeshttps://doi.org/10.1159/000486374openalex-snapshot

A Critical Review of the Consensus Statement from the European Atherosclerosis Society Consensus Panel 2017

inferred← citeshttps://doi.org/10.1159/000543337openalex-snapshot

Dynamic Observation of Colonic Lesions, Commensal Microbiome, and Mycobiome Variations in Trinitrobenzene Sulfonic Acid-Induced Experimental Crohn’s Disease in Rats

inferred← citeshttps://doi.org/10.11606/d.5.2022.tde-01022023-092430openalex-snapshot

Diferenças sexuais nas redes de regulação gênica durante o período fetal do neurodesenvolvimento

inferred← citeshttps://doi.org/10.1172/jci.insight.188459openalex-snapshot

Chronic integrated stress response causes dysregulated cholesterol synthesis in white matter disease

inferred← citeshttps://doi.org/10.1177/23969873221148229openalex-snapshot

Association of cholesterol levels with hemorrhagic transformation and cerebral edema after reperfusion therapies

inferred← citeshttps://doi.org/10.1186/s12876-020-01195-1openalex-snapshot

Intestinal flora imbalance affects bile acid metabolism and is associated with gallstone formation

inferred← citeshttps://doi.org/10.1186/s12883-025-04284-4openalex-snapshot

Associations between serum lipid levels and cognitive impairment in hypertensive patients: a case-control study

inferred← citeshttps://doi.org/10.1186/s12918-015-0253-0openalex-snapshot

Scope and limitations of yeast as a model organism for studying human tissue-specific pathways

inferred← citeshttps://doi.org/10.1186/s12974-022-02409-xopenalex-snapshot

Lowering blood cholesterol does not affect neuroinflammation in experimental autoimmune encephalomyelitis

inferred← citeshttps://doi.org/10.1186/s12987-025-00721-1openalex-snapshot

Mechanisms of high-density lipoprotein in regulating blood-brain barrier function: insights and implications

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