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ALDH2 Overexpression Alleviates High Glucose-Induced Cardiotoxicity by Inhibiting NLRP3 Inflammasome Activation
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1 of the 31 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-28): 10.1186/1741-7015-10-40 (notice 2022-07-08).
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/cphy.c160021openalex-snapshot
Pathophysiological Fundamentals of Diabetic Cardiomyopathy
inferredcites →https://doi.org/10.1007/s00125-014-3171-6openalex-snapshot
Molecular mechanisms of diabetic cardiomyopathy
inferredcites →https://doi.org/10.1016/j.bbadis.2014.05.017openalex-snapshot
A novel protective mechanism for mitochondrial aldehyde dehydrogenase (ALDH2) in type i diabetes-induced cardiac dysfunction: Role of AMPK-regulated autophagy
inferredcites →https://doi.org/10.1016/j.brainres.2018.06.008openalex-snapshot
The pathological role of NLRs and AIM2 inflammasome-mediated pyroptosis in damaged blood-brain barrier after traumatic brain injury
inferredcites →https://doi.org/10.1016/j.chom.2010.06.007openalex-snapshot
Manipulation of Host Cell Death Pathways during Microbial Infections
inferredcites →https://doi.org/10.1016/j.fct.2018.12.017openalex-snapshot
Single nanomolar doxorubicin exposure triggers compensatory mitochondrial responses in H9c2 cardiomyoblasts
inferredcites →https://doi.org/10.1016/j.pharmthera.2011.05.008openalex-snapshot
ALDH2 in alcoholic heart diseases: Molecular mechanism and clinical implications
inferredcites →https://doi.org/10.1016/j.redox.2014.12.011openalex-snapshot
Role of lipid peroxidation derived 4-hydroxynonenal (4-HNE) in cancer: Focusing on mitochondria
inferredcites →https://doi.org/10.1016/j.redox.2015.01.008openalex-snapshot
NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases
inferredcites →https://doi.org/10.1016/j.tibs.2016.10.004openalex-snapshot
Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death
inferredcites →https://doi.org/10.1038/nature09663openalex-snapshot
A role for mitochondria in NLRP3 inflammasome activation
inferredcites →https://doi.org/10.1038/nri2296openalex-snapshot
NLRs at the intersection of cell death and immunity
inferredcites →https://doi.org/10.1080/10715762.2018.1459042openalex-snapshot
Alda-1, an ALDH2 activator, protects against hepatic ischemia/reperfusion injury in rats via inhibition of oxidative stress
inferredcites →https://doi.org/10.1111/imr.12621openalex-snapshot
Overview of the IL ‐1 family in innate inflammation and acquired immunity
inferredcites →https://doi.org/10.1126/science.aaf2154openalex-snapshot
Programmed necrosis in inflammation: Toward identification of the effector molecules
inferredcites →https://doi.org/10.1152/physrev.00018.2001openalex-snapshot
Free Radicals in the Physiological Control of Cell Function
inferredcites →https://doi.org/10.1155/2016/1390861openalex-snapshot
ALDH2 Inhibition Potentiates High Glucose Stress-Induced Injury in Cultured Cardiomyocytes
inferredcites →https://doi.org/10.1155/2016/6190504openalex-snapshot
Activation of ALDH2 with Low Concentration of Ethanol Attenuates Myocardial Ischemia/Reperfusion Injury in Diabetes Rat Model
inferredcites →https://doi.org/10.1159/isbn.978-3-318-02791-4openalex-snapshot
Translational Neurosonology
inferredcites →https://doi.org/10.1167/iovs.18-23965openalex-snapshot
Hyperosmotic Stress–Induced TRPM2 Channel Activation Stimulates NLRP3 Inflammasome Activity in Primary Human Corneal Epithelial Cells
inferredcites →https://doi.org/10.1186/1741-7015-10-40openalex-snapshot
RETRACTED ARTICLE: Mitochondrial aldehyde dehydrogenase (ALDH2) protects against streptozotocin-induced diabetic cardiomyopathy: role of GSK3β and mitochondrial function
inferredcites →https://doi.org/10.1194/jlr.m038638openalex-snapshot
Obese adipocytes show ultrastructural features of stressed cells and die of pyroptosis
inferredcites →https://doi.org/10.1371/journal.pone.0104771openalex-snapshot
NLRP3 Gene Silencing Ameliorates Diabetic Cardiomyopathy in a Type 2 Diabetes Rat Model
inferredcites →https://doi.org/10.2337/db07-0481openalex-snapshot
Mitochondrial Energetics in the Heart in Obesity-Related Diabetes
inferredcites →https://doi.org/10.3389/fncel.2014.00216openalex-snapshot
Role of mitochondria ROS generation in ethanol-induced NLRP3 inflammasome activation and cell death in astroglial cells
inferredcites →https://doi.org/10.3389/fphar.2017.00141openalex-snapshot
Serelaxin Treatment Reduces Oxidative Stress and Increases Aldehyde Dehydrogenase-2 to Attenuate Nitrate Tolerance
inferredcites →https://doi.org/10.3892/ijmm.2018.3880openalex-snapshot
Silencing of NOD2 protects against diabetic cardiomyopathy in a murine diabetes model
inferredcites →https://doi.org/10.3892/mmr.2013.1524openalex-snapshot
Changes in cardiac mitochondrial aldehyde dehydrogenase 2 activity in relation to oxidative stress and inflammatory injury in diabetic rats
inferredcites →https://doi.org/10.7150/ijbs.33568openalex-snapshot
Role of Pyroptosis in Cardiovascular Diseases and its Therapeutic Implications
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4794612openalex-extracted
Molecular Mechanism of 4-Hydroxynonenal Induced Cell Death
inferred← citeshttps://doi.org/10.1002/jcp.30285openalex-snapshot
The NLRP3 inflammasome: Multiple activation pathways and its role in primary cells during ventricular remodeling
inferred← citeshttps://doi.org/10.1002/jcp.30627openalex-snapshot
Pyroptosis: A possible link between obesity‐related inflammation and inflammatory diseases
inferred← citeshttps://doi.org/10.1007/s12094-023-03190-wopenalex-snapshot
ALDH2 activation attenuates oxygen–glucose deprivation/reoxygenation-induced cell apoptosis, pyroptosis, ferroptosis and autophagy
inferred← citeshttps://doi.org/10.1016/j.abb.2023.109621openalex-snapshot
ALDH2 ameliorates ethanol-induced gastric ulcer through suppressing NLPR3 inflammasome activation and ferroptosis
inferred← citeshttps://doi.org/10.1016/j.apsb.2021.08.026openalex-snapshot
Preliminary evidence for the presence of multiple forms of cell death in diabetes cardiomyopathy
inferred← citeshttps://doi.org/10.1016/j.brainresbull.2023.01.012openalex-snapshot
Acetaldehyde dehydrogenase 2 activation attenuates sepsis-induced brain injury through NLRP3 inflammasome regulation
inferred← citeshttps://doi.org/10.1016/j.cellsig.2024.111287openalex-snapshot
DSCR1–1 attenuates osteoarthritis-associated chondrocyte injury by regulating the CREB1/ALDH2/Wnt/β-catenin axis: An in vitro and in vivo study
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2021.03.046openalex-snapshot
Therapeutic potential of targeting oxidative stress in diabetic cardiomyopathy
inferred← citeshttps://doi.org/10.1016/j.hrthm.2022.05.008openalex-snapshot
Aldehyde dehydrogenase 2 and arrhythmogenesis
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.112056openalex-snapshot
IRE1α regulates macrophage polarization in type 2 diabetic periodontitis through promoting endoplasmic reticulum stress
inferred← citeshttps://doi.org/10.1016/j.jdiacomp.2024.108848openalex-snapshot
The mechanism and promising therapeutic strategy of diabetic cardiomyopathy dysfunctions: Focus on pyroptosis
inferred← citeshttps://doi.org/10.1016/j.lfs.2021.119116openalex-snapshot
Inhibition of SGLT1 protects against glycemic variability-induced cardiac damage and pyroptosis of cardiomyocytes in diabetic mice
inferred← citeshttps://doi.org/10.1016/j.phrs.2021.106049openalex-snapshot
Sodium glucose cotransporter 1 (SGLT1) inhibitors in cardiovascular protection: Mechanism progresses and challenges
inferred← citeshttps://doi.org/10.1016/j.yexcr.2022.113320openalex-snapshot
LncRNA-MEG3 attenuates hyperglycemia-induced damage by enhancing mitochondrial translocation of HSP90A in the primary hippocampal neurons
inferred← citeshttps://doi.org/10.1038/s41419-021-04484-zopenalex-snapshot
METTL14 suppresses pyroptosis and diabetic cardiomyopathy by downregulating TINCR lncRNA
inferred← citeshttps://doi.org/10.1038/s41569-023-00839-5openalex-snapshot
The role of aldehyde dehydrogenase 2 in cardiovascular disease
inferred← citeshttps://doi.org/10.1038/s41598-025-02022-xopenalex-snapshot
Mitochondrial aldehyde dehydrogenase restores the migratory capacity inhibited by high glucose-induced hyperosmolality
inferred← citeshttps://doi.org/10.1042/cs20210189openalex-snapshot
Vincristine attenuates cardiac fibrosis through the inhibition of NLRP3 inflammasome activation
inferred← citeshttps://doi.org/10.1080/00952990.2023.2297349openalex-snapshot
Ethanol causes non-communicable disease through activation of NLRP3 inflammasome: a review on mechanism of action and potential interventions
inferred← citeshttps://doi.org/10.1080/01902148.2024.2303474openalex-snapshot
Hsa_circ_0008833 promotes COPD progression via inducing pyroptosis in bronchial epithelial cells
inferred← citeshttps://doi.org/10.1080/21655979.2022.2033381openalex-snapshot
Crosstalk of pyroptosis, ferroptosis, and mitochondrial aldehyde dehydrogenase 2-related mechanisms in sepsis-induced lung injury in a mouse model
inferred← citeshttps://doi.org/10.1097/cp9.0000000000000002openalex-snapshot
Aldehyde dehydrogenase 2-associated metabolic abnormalities and cardiovascular diseases: current status, underlying mechanisms, and clinical recommendations
inferred← citeshttps://doi.org/10.1155/2020/3589871openalex-snapshot
[Retracted] Circular RNA circFAT1(e2) Promotes Osteosarcoma Progression and Metastasis by Sponging miR‐181b and Regulating HK2 Expression
inferred← citeshttps://doi.org/10.1155/2021/9813687openalex-snapshot
Corrigendum to “ALDH2 Overexpression Alleviates High Glucose-Induced Cardiotoxicity by Inhibiting NLRP3 Inflammasome Activation”
inferred← citeshttps://doi.org/10.1155/2022/5277673openalex-snapshot
Targeting Pyroptosis: New Insights into the Treatment of Diabetic Microvascular Complications
inferred← citeshttps://doi.org/10.1155/2022/5913374openalex-snapshot
Oxidative Stress Signaling Mediated Pathogenesis of Diabetic Cardiomyopathy
inferred← citeshttps://doi.org/10.1155/cdr/5289405openalex-snapshot
Aldehyde Dehydrogenase‐2 Alleviates Septic Myocardial Injury by Inhibiting Caspase‐11‐Mediated Noncanonical Pyroptosis
inferred← citeshttps://doi.org/10.1177/09731296251385377openalex-snapshot
Effects of Resveratrol on Cardiomyocyte Hypoxia-reoxygenation Injury Induced by High Glucose and Its Relationship with NRG1/ErbB Pathway
inferred← citeshttps://doi.org/10.1177/14703203261431906openalex-snapshot
The role of oxidative stress in the pathophysiology of diabetic cardiomyopathy: Crosstalk of inflammatory pathways
inferred← citeshttps://doi.org/10.1177/15353702211013308openalex-snapshot
Protective effect of aldehyde dehydrogenase 2 against rat corneal dysfunction caused by streptozotocin-induced type I diabetes
inferred← citeshttps://doi.org/10.11817/j.issn.1672-7347.2022.220086openalex-snapshot
Trimethylamine oxide induces pyroptosis of vascular endothelial cells through ALDH2/ROS/NLRP3/GSDMD pathway.
inferred← citeshttps://doi.org/10.1186/s12872-024-04010-xopenalex-snapshot
Effect of NLRP3 gene knockdown on pyroptosis and ferroptosis in diabetic cardiomyopathy injury
inferred← citeshttps://doi.org/10.1186/s12938-021-00917-0openalex-snapshot
Aldehyde dehydrogenase 2 alleviates monosodium iodoacetate-induced oxidative stress, inflammation and apoptosis in chondrocytes via inhibiting aquaporin 4 expression
inferred← citeshttps://doi.org/10.1186/s40779-025-00646-8openalex-snapshot
ALDH2 in autophagy and cell death: molecular mechanisms and implications for diseases
inferred← citeshttps://doi.org/10.12122/j.issn.1673-4254.2021.07.03openalex-snapshot
[Inhibition of mitochondrial reactive oxygen species reduces high glucose-induced pyroptosis and ferroptosis in H9C2 cardiac myocytes].
inferred← citeshttps://doi.org/10.12122/j.issn.1673-4254.2024.01.19openalex-snapshot
[Spermidine alleviates lipopolysaccharide-induced myocardial injury in mice by suppressing apoptosis, ROS production and ferroptosis].
inferred← citeshttps://doi.org/10.14715/cmb/2020.66.6.11openalex-snapshot
MiRNA-214 promotes the pyroptosis and inhibits the proliferation of cervical cancer cells via regulating the expression of NLRP3
inferred← citeshttps://doi.org/10.21037/atm-20-5838openalex-snapshot
Dihydromyricetin attenuates neuropathic pain via enhancing the transition from M1 to M2 phenotype polarization by potentially elevating ALDH2 activity in vitro and vivo
inferred← citeshttps://doi.org/10.21203/rs.3.rs-7102103/v1openalex-snapshot
ALDH2 Suppresses Glycolysis in Hepatocellular Carcinoma via TRIM21-Mediated GLUT1 Degradation
inferred← citeshttps://doi.org/10.2147/dmso.s300388openalex-snapshot
Changes of Necroptosis in Irbesartan Medicated Cardioprotection in Diabetic Rats
inferred← citeshttps://doi.org/10.31083/fbl37139openalex-snapshot
Short Overview on the Involvement of Lipid Peroxidation Product 4-Hydroxynonenal in Diverse Pathways of Cell Death
inferred← citeshttps://doi.org/10.3389/fcvm.2022.870999openalex-snapshot
KDM3A Inhibition Ameliorates Hyperglycemia-Mediated Myocardial Injury by Epigenetic Modulation of Nuclear Factor Kappa-B/P65
inferred← citeshttps://doi.org/10.3389/fcvm.2023.1062502openalex-snapshot
Aldehyde dehydrogenase 2 and NOD-like receptor thermal protein domain associated protein 3 inflammasome in atherosclerotic cardiovascular diseases: A systematic review of the current evidence
inferred← citeshttps://doi.org/10.3389/fendo.2022.1011669openalex-snapshot
Canagliflozin mitigates ferroptosis and improves myocardial oxidative stress in mice with diabetic cardiomyopathy
inferred← citeshttps://doi.org/10.3389/fendo.2022.907060openalex-snapshot
Emerging Role of Epitranscriptomics in Diabetes Mellitus and Its Complications
inferred← citeshttps://doi.org/10.3389/fmicb.2023.1209358openalex-snapshot
Role of sodium pyruvate in maintaining the survival and cytotoxicity of Staphylococcus aureus under high glucose conditions
inferred← citeshttps://doi.org/10.3390/biomedicines11030662openalex-snapshot
Emerging Therapy for Diabetic Cardiomyopathy: From Molecular Mechanism to Clinical Practice
inferred← citeshttps://doi.org/10.3390/ijms21041456openalex-snapshot
Mechanisms and Therapeutic Regulation of Pyroptosis in Inflammatory Diseases and Cancer
inferred← citeshttps://doi.org/10.3390/ijms21155477openalex-snapshot
Does the Act of Copulation per se, without Considering Seminal Deposition, Change the Expression of Genes in the Porcine Female Genital Tract?
inferred← citeshttps://doi.org/10.3390/ijms26125516openalex-snapshot
ALDH2 Enzyme Deficiency in Diabetic Cardiomyopathy
inferred← citeshttps://doi.org/10.3390/ph18010134openalex-snapshot
Critical Appraisal of Pharmaceutical Therapy in Diabetic Cardiomyopathy—Challenges and Prospectives
inferred← citeshttps://doi.org/10.3892/etm.2021.10376openalex-snapshot
Rutin alleviates cardiomyocyte injury induced by high glucose through inhibiting apoptosis and endoplasmic reticulum stress
inferred← citeshttps://doi.org/10.3892/mmr.2022.12735openalex-snapshot
lncRNA GAS5 promotes pyroptosis in COPD by functioning as a ceRNA to regulate the miR‑223‑3p/NLRP3 axis
inferred← citeshttps://doi.org/10.6084/m9.figshare.26747702openalex-snapshot
Additional file 1 of Effect of NLRP3 gene knockdown on pyroptosis and ferroptosis in diabetic cardiomyopathy injury
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