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Apelin, an APJ Receptor Ligand, Regulates Body Adiposity and Favors the Messenger Ribonucleic Acid Expression of Uncoupling Proteins in Mice

https://doi.org/10.1210/en.2006-1270

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1006/abio.1976.9999openalex-snapshot

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

inferredcites →https://doi.org/10.1006/bbrc.1997.6740openalex-snapshot

UCP3: An Uncoupling Protein Homologue Expressed Preferentially and Abundantly in Skeletal Muscle and Brown Adipose Tissue

inferredcites →https://doi.org/10.1006/bbrc.1998.9489openalex-snapshot

Isolation and Characterization of a Novel Endogenous Peptide Ligand for the Human APJ Receptor

inferredcites →https://doi.org/10.1006/bbrc.2002.6575openalex-snapshot

The Effects of Centrally Administered Apelin-13 on Food Intake, Water Intake and Pituitary Hormone Release in Rats

inferredcites →https://doi.org/10.1016/0006-8993(93)91702-topenalex-snapshot

Sympathetic nerve activity after discrete hypothalamic injections of l-glutamate

inferredcites →https://doi.org/10.1016/j.febslet.2006.04.028openalex-snapshot

The metabolic syndrome and adipocytokines

inferredcites →https://doi.org/10.1016/j.neuroscience.2003.11.039openalex-snapshot

Hypothalamic neuronal histamine regulates sympathetic nerve activity and expression of uncoupling protein 1 mRNA in brown adipose tissue in rats

inferredcites →https://doi.org/10.1016/j.regpep.2005.08.003openalex-snapshot

Regulation of apelin mRNA expression by insulin and glucocorticoids in mouse 3T3-L1 adipocytes

inferredcites →https://doi.org/10.1016/j.tips.2006.03.008openalex-snapshot

The hypothalamic H1 receptor: a novel therapeutic target for disrupting diurnal feeding rhythm and obesity

inferredcites →https://doi.org/10.1016/s0014-5793(97)00384-0openalex-snapshot

Uncoupling protein‐3: a new member of the mitochondrial carrier family with tissue‐specific expression

inferredcites →https://doi.org/10.1016/s0014-5793(97)01381-1openalex-snapshot

Cloning of rat uncoupling protein‐3 and uncoupling protein‐2 cDNAs: their gene expression in rats fed high‐fat diet

inferredcites →https://doi.org/10.1016/s0167-0115(01)00236-1openalex-snapshot

The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism

inferredcites →https://doi.org/10.1016/s0167-4781(00)00072-5openalex-snapshot

Distribution of mRNA encoding B78/apj, the rat homologue of the human APJ receptor, and its endogenous ligand apelin in brain and peripheral tissues

inferredcites →https://doi.org/10.1016/s0304-3940(03)00351-3openalex-snapshot

Intracerebroventricular injection of apelin-13 reduces food intake in the rat

inferredcites →https://doi.org/10.1038/281031a0openalex-snapshot

A role for brown adipose tissue in diet-induced thermogenesis

inferredcites →https://doi.org/10.1038/387090a0openalex-snapshot

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

inferredcites →https://doi.org/10.1038/nature01705openalex-snapshot

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

inferredcites →https://doi.org/10.1038/nm788openalex-snapshot

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

inferredcites →https://doi.org/10.1046/j.1365-2826.2003.01044.xopenalex-snapshot

Regulation of Rat APJ Receptor Messenger Ribonucleic Acid Expression in Magnocellular Neurones of the Paraventricular and Supraopric Nuclei by Osmotic Stimuli

inferredcites →https://doi.org/10.1046/j.1471-4159.2000.0740034.xopenalex-snapshot

Characterization of Apelin, the Ligand for the APJ Receptor

inferredcites →https://doi.org/10.1046/j.1471-4159.2001.00320.xopenalex-snapshot

Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain

inferredcites →https://doi.org/10.1046/j.1471-4159.2003.01587.xopenalex-snapshot

Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin

inferredcites →https://doi.org/10.1074/jbc.272.39.24129openalex-snapshot

Uncoupling Protein-3 Is a Mediator of Thermogenesis Regulated by Thyroid Hormone, β3-Adrenergic Agonists, and Leptin

inferredcites →https://doi.org/10.1074/jbc.m908417199openalex-snapshot

Molecular and Functional Characteristics of APJ

inferredcites →https://doi.org/10.1096/fasebj.4.11.2199286openalex-snapshot

Brown adipose tissue thermogenesis: interdisciplinary studies

inferredcites →https://doi.org/10.1152/ajpendo.1998.275.2.e259openalex-snapshot

Leptin induction of UCP1 gene expression is dependent on sympathetic innervation

inferredcites →https://doi.org/10.1152/ajpregu.1999.276.6.r1569openalex-snapshot

CNS origins of the sympathetic nervous system outflow to brown adipose tissue

inferredcites →https://doi.org/10.1152/physrev.1984.64.1.1openalex-snapshot

Thermogenic mechanisms in brown fat.

inferredcites →https://doi.org/10.1161/01.res.0000033522.37861.69openalex-snapshot

Apelin, the Novel Endogenous Ligand of the Orphan Receptor APJ, Regulates Cardiac Contractility

inferredcites →https://doi.org/10.1210/en.2003-1116openalex-snapshot

Apelin, a New Enteric Peptide: Localization in the Gastrointestinal Tract, Ontogeny, and Stimulation of Gastric Cell Proliferation and of Cholecystokinin Secretion

inferredcites →https://doi.org/10.1210/en.2004-0384openalex-snapshot

Dehydration-Induced Cross-Regulation of Apelin and Vasopressin Immunoreactivity Levels in Magnocellular Hypothalamic Neurons

inferredcites →https://doi.org/10.1210/en.2004-1427openalex-snapshot

Apelin, a Newly Identified Adipokine Up-Regulated by Insulin and Obesity

inferredcites →https://doi.org/10.1210/er.2005-0005openalex-snapshot

Adiponectin and Adiponectin Receptors

inferredcites →https://doi.org/10.2337/db05-0266openalex-snapshot

Phosphatidylinositol 3-Kinase–Dependent Activation of Akt, an Essential Signal for Hyperthermia-Induced Heat-Shock Protein 72, Is Attenuated in Streptozotocin-Induced Diabetic Heart

inferredcites →https://doi.org/10.2337/diab.46.5.900openalex-snapshot

Cloning and Characterization of an Uncoupling Protein Homolog: A Potential Molecular Mediator of Human Thermogenesis

inferredcites →https://doi.org/10.2337/diabetes.47.7.1014openalex-snapshot

Chronic central leptin infusion enhances insulin-stimulated glucose metabolism and favors the expression of uncoupling proteins.

inferredcites →https://doi.org/10.2337/diabetes.50.2.376openalex-snapshot

Central Infusion of Histamine Reduces Fat Accumulation and Upregulates UCP Family in Leptin-Resistant Obese Mice

inferredcites →https://doi.org/10.2337/diabetes.50.2.385openalex-snapshot

Targeted Disruption of Histamine H1-Receptor Attenuates Regulatory Effects of Leptin on Feeding, Adiposity, and UCP Family in Mice

inferredcites →https://doi.org/10.2337/diabetes.52.9.2266openalex-snapshot

Peripheral, But Not Central, Administration of Adiponectin Reduces Visceral Adiposity and Upregulates the Expression of Uncoupling Protein in Agouti Yellow ( Ay/a ) Obese Mice

inferredcites →https://doi.org/10.2337/diabetes.53.2007.s130openalex-snapshot

The Biology of Mitochondrial Uncoupling Proteins

inferredcites →https://doi.org/10.2337/diabetes.53.9.2250openalex-snapshot

Involvement of Hypothalamic Histamine H1 Receptor in the Regulation of Feeding Rhythm and Obesity

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4074496openalex-extracted

The Role of Apelin in Obesity Treatment by Exercise Training

inferred← citeshttps://doi.org/10.1002/9781118829875.refsopenalex-snapshot

References

inferred← citeshttps://doi.org/10.1002/9781444307627.ch9openalex-snapshot

Adipocyte Biology

inferred← citeshttps://doi.org/10.1002/bab.2142openalex-snapshot

Supplement therapy with apelin for improving the TSH level and lipid disorders in PTU‐induced hypothyroid rats

inferred← citeshttps://doi.org/10.1002/cbin.11191openalex-snapshot

Apelin and stem cells: the role played in the cardiovascular system and energy metabolism

inferred← citeshttps://doi.org/10.1002/cphy.c160045openalex-snapshot

CNS Targets of Adipokines

inferred← citeshttps://doi.org/10.1002/cphy.c170028openalex-snapshot

Apelinergic System Structure and Function

inferred← citeshttps://doi.org/10.1002/cphy.c170042openalex-snapshot

Adipose Organ Development and Remodeling

inferred← citeshttps://doi.org/10.1002/j.2040-4603.2017.tb00781.xopenalex-snapshot

CNS Targets of Adipokines

inferred← citeshttps://doi.org/10.1002/j.2040-4603.2018.tb00012.xopenalex-snapshot

Apelinergic System Structure and Function

inferred← citeshttps://doi.org/10.1002/j.2040-4603.2018.tb00046.xopenalex-snapshot

Adipose Organ Development and Remodeling

inferred← citeshttps://doi.org/10.1002/jcp.26492openalex-snapshot

Biological functions of Elabela, a novel endogenous ligand of APJ receptor

inferred← citeshttps://doi.org/10.1002/jnr.24895openalex-snapshot

Impact of the apelin/APJ axis in the pathogenesis of Parkinson’s disease with therapeutic potential

inferred← citeshttps://doi.org/10.1002/pmic.201000145openalex-snapshot

Peptidomic profiling of human cerebrospinal fluid identifies YPRPIHPA as a novel substrate for prolylcarboxypeptidase

inferred← citeshttps://doi.org/10.1007/978-1-4614-8069-3_10openalex-snapshot

Leptin, Adiponectin, and Other Adipokines in Regulation of Adipose Tissue Angiogenesis

inferred← citeshttps://doi.org/10.1007/978-2-8178-0332-6_14openalex-snapshot

Fonctions métaboliques de l’apeline

inferred← citeshttps://doi.org/10.1007/978-2-8178-0343-2_14openalex-snapshot

Apelin Metabolic Functions

inferred← citeshttps://doi.org/10.1007/978-3-031-40116-9_56openalex-snapshot

Obesity, Myokines, and Metabolic Health

inferred← citeshttps://doi.org/10.1007/978-3-031-88361-3_22openalex-snapshot

Skeletal Muscle as Endocrine Organ

inferred← citeshttps://doi.org/10.1007/978-3-319-12125-3_56-1openalex-snapshot

Obesity, Myokines, and Metabolic Health

inferred← citeshttps://doi.org/10.1007/978-3-319-41677-9_7openalex-snapshot

Apelin and Cancer

inferred← citeshttps://doi.org/10.1007/978-3-642-00300-4_11openalex-snapshot

Adipokines: Regulators of Lipid Metabolism

inferred← citeshttps://doi.org/10.1007/bf03165767openalex-snapshot

Expanding role for the apelin/APJ system in physiopathology

inferred← citeshttps://doi.org/10.1007/s00431-023-05315-3openalex-snapshot

Serum apelin-12 and obesity-related markers in Egyptian children with Down syndrome

inferred← citeshttps://doi.org/10.1007/s10354-010-0781-6openalex-snapshot

Adipokine update – neue Moleküle, neue Funktionen

inferred← citeshttps://doi.org/10.1007/s10557-010-6274-4openalex-snapshot

Blockade of the Renin-Angiotensin System Ameliorates Apelin Production in 3T3-L1 Adipocytes

inferred← citeshttps://doi.org/10.1007/s10620-008-0585-3openalex-snapshot

Adipose Tissue: The New Endocrine Organ? A Review Article

inferred← citeshttps://doi.org/10.1007/s10989-017-9638-9openalex-snapshot

Effect of Intracerebroventricular Administration of Apelin-13 on the Hypothalamus–Pituitary–Thyroid Axis and Peripheral Uncoupling Proteins

inferred← citeshttps://doi.org/10.1007/s11690-008-0101-0openalex-snapshot

Adipokines: quelles nouvelles ?

inferred← citeshttps://doi.org/10.1007/s11690-011-0292-7openalex-snapshot

Effets métaboliques de l’apeline sur le tissu adipeux humain

inferred← citeshttps://doi.org/10.1007/s12020-011-9507-9openalex-snapshot

Apelin, diabetes, and obesity

inferred← citeshttps://doi.org/10.1007/s12035-025-05519-8openalex-snapshot

Apelin Regulates PVN Dopaminergic Activity and Limits Weight Gain in Mice: An Effect Attenuated by High-Fat Diet

inferred← citeshttps://doi.org/10.1007/s13410-015-0416-yopenalex-snapshot

Omentin and apelin concentrations in relation to obesity, diabetes mellitus type two, and cardiovascular diseases in Egyptian population

inferred← citeshttps://doi.org/10.1007/s13679-015-0174-7openalex-snapshot

Novel Mediators of Adipose Tissue and Muscle Crosstalk

inferred← citeshttps://doi.org/10.1016/b978-0-12-385095-9.00160-3openalex-snapshot

Apelin

inferred← citeshttps://doi.org/10.1016/j.advms.2014.11.001openalex-snapshot

The effects of apelin treatment on a rat model of type 2 diabetes

inferred← citeshttps://doi.org/10.1016/j.ajme.2017.05.006openalex-snapshot

Ameliorative effect of apelin on streptozotocin-induced diabetes and its associated cardiac hypertrophy

inferred← citeshttps://doi.org/10.1016/j.ando.2016.01.001openalex-snapshot

New adipokines

inferred← citeshttps://doi.org/10.1016/j.bbagen.2011.05.004openalex-snapshot

Apelin-transgenic mice exhibit a resistance against diet-induced obesity by increasing vascular mass and mitochondrial biogenesis in skeletal muscle

inferred← citeshttps://doi.org/10.1016/j.bbapap.2016.07.004openalex-snapshot

Prolyl carboxypeptidase purified from human placenta: its characterization and identification as an apelin-cleaving enzyme

inferred← citeshttps://doi.org/10.1016/j.bbr.2020.113059openalex-snapshot

Aplnr knockout mice display sex-specific changes in conditioned fear

inferred← citeshttps://doi.org/10.1016/j.bbr.2023.114536openalex-snapshot

Hypophagia induced by intracerebroventricular injection of apelin-13 is mediated via CRF1/CRF2 and MC3/MC4 receptors in neonatal broiler chicken

inferred← citeshttps://doi.org/10.1016/j.bbrc.2008.02.008openalex-snapshot

A putative role for apelin in the etiology of obesity

inferred← citeshttps://doi.org/10.1016/j.bcp.2017.10.002openalex-snapshot

Acylated apelin-13 amide analogues exhibit enzyme resistance and prolonged insulin releasing, glucose lowering and anorexic properties

inferred← citeshttps://doi.org/10.1016/j.brainresbull.2012.02.004openalex-snapshot

Apelin-13 microinjection into the paraventricular nucleus increased sympathetic nerve activity innervating brown adipose tissue in rats

inferred← citeshttps://doi.org/10.1016/j.cardfail.2015.03.007openalex-snapshot

The Emerging Potential of the Apelin-APJ System in Heart Failure

inferred← citeshttps://doi.org/10.1016/j.celrep.2020.108461openalex-snapshot

Maternal Inactivity Programs Skeletal Muscle Dysfunction in Offspring Mice by Attenuating Apelin Signaling and Mitochondrial Biogenesis

inferred← citeshttps://doi.org/10.1016/j.cmet.2008.10.003openalex-snapshot

Apelin Stimulates Glucose Utilization in Normal and Obese Insulin-Resistant Mice

inferred← citeshttps://doi.org/10.1016/j.cnd.2010.05.002openalex-snapshot

L’apéline : une nouvelle adipokine impliquée dans le métabolisme énergétique

inferred← citeshttps://doi.org/10.1016/j.diabres.2015.05.016openalex-snapshot

Genotype screening of APLN rs3115757 variant in Egyptian women population reveals an association with obesity and insulin resistance

inferred← citeshttps://doi.org/10.1016/j.diabres.2018.12.012openalex-snapshot

Elevated blood apelin levels in type 2 diabetes mellitus: A systematic review and meta-analysis

inferred← citeshttps://doi.org/10.1016/j.drudis.2012.04.007openalex-snapshot

Physiological, pathological and potential therapeutic roles of adipokines

inferred← citeshttps://doi.org/10.1016/j.ejim.2011.08.009openalex-snapshot

Traditional and novel cardiovascular risk factors in non-functioning adrenal adenomas

inferred← citeshttps://doi.org/10.1016/j.ejmhg.2014.11.004openalex-snapshot

Apelin rs2235306 polymorphism is not related to metabolic syndrome in Egyptian women

inferred← citeshttps://doi.org/10.1016/j.exger.2019.110710openalex-snapshot

Effects of exercise-induced apelin on muscle function and cognitive function in aged mice

inferred← citeshttps://doi.org/10.1016/j.gene.2016.09.025openalex-snapshot

Exogenous apelin changes alpha and beta myosin heavy chain mRNA expression and improves cardiac function in PTU-induced hypothyroid rats

inferred← citeshttps://doi.org/10.1016/j.gene.2025.149591openalex-snapshot

Insights into the function and research status of membrane protein APJ

inferred← citeshttps://doi.org/10.1016/j.jacc.2025.06.055openalex-snapshot

The Adipokine Hypothesis of Heart Failure With a Preserved Ejection Fraction

inferred← citeshttps://doi.org/10.1016/j.jgeb.2017.05.002openalex-snapshot

Serum apelin levels and metabolic risk markers in obese women

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2007.06.006openalex-snapshot

Role of adipocytokines in obesity-associated insulin resistance

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2023.109350openalex-snapshot

(-)-Epicatechin increases apelin/APLNR expression and modifies proteins involved in lipid metabolism of offspring descendants of maternal obesity

inferred← citeshttps://doi.org/10.1016/j.lfs.2020.118310openalex-snapshot

Apelin/Apelin receptor: A new therapeutic target in Polycystic Ovary Syndrome

inferred← citeshttps://doi.org/10.1016/j.mce.2009.07.031openalex-snapshot

Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome

inferred← citeshttps://doi.org/10.1016/j.mce.2009.11.011openalex-snapshot

The autocrine and paracrine roles of adipokines

inferred← citeshttps://doi.org/10.1016/j.mce.2012.01.005openalex-snapshot

Apelin secretion and expression of apelin receptors in 3T3-L1 adipocytes are differentially regulated by angiotensin type 1 and type 2 receptors

inferred← citeshttps://doi.org/10.1016/j.mce.2012.07.002openalex-snapshot

Apelin inhibits adipogenesis and lipolysis through distinct molecular pathways

inferred← citeshttps://doi.org/10.1016/j.mce.2021.111278openalex-snapshot

The therapeutic potentials of apelin in obesity-associated diseases

inferred← citeshttps://doi.org/10.1016/j.metabol.2009.04.036openalex-snapshot

18F9 (4-(3,6-bis (ethoxycarbonyl)-4,5,6,7-tetrahydrothieno (2,3-c) pyridin-2-ylamino)-4-oxobutanoic acid) enhances insulin-mediated glucose uptake in vitro and exhibits antidiabetic activity in vivo in db/db mice

inferred← citeshttps://doi.org/10.1016/j.metabol.2009.08.005openalex-snapshot

Effects of rosiglitazone and metformin treatment on apelin, visfatin, and ghrelin levels in patients with type 2 diabetes mellitus

inferred← citeshttps://doi.org/10.1016/j.metabol.2012.12.014openalex-snapshot

Cellular mechanisms regulating fuel metabolism in mammals: Role of adipose tissue and lipids during prolonged food deprivation

inferred← citeshttps://doi.org/10.1016/j.neuropharm.2022.109235openalex-snapshot

Neuropeptide apelin presented in the dopaminergic neurons modulates the neuronal excitability in the substantia nigra pars compacta

inferred← citeshttps://doi.org/10.1016/j.npep.2009.11.002openalex-snapshot

Genome-wide census and expression profiling of chicken neuropeptide and prohormone convertase genes

inferred← citeshttps://doi.org/10.1016/j.npep.2019.101975openalex-snapshot

The influence of post-infarct heart failure and high fat diet on the expression of apelin APJ and vasopressin V1a and V1b receptors

inferred← citeshttps://doi.org/10.1016/j.npep.2023.102382openalex-snapshot

The regulatory effects of the apelin/APJ system on depression: A prospective therapeutic target

inferred← citeshttps://doi.org/10.1016/j.pbiomolbio.2017.09.013openalex-snapshot

Load-dependent effects of apelin on murine cardiomyocytes

inferred← citeshttps://doi.org/10.1016/j.peptides.2009.04.020openalex-snapshot

Apelin in goldfish (Carassius auratus): Cloning, distribution and role in appetite regulation

inferred← citeshttps://doi.org/10.1016/j.peptides.2013.03.024openalex-snapshot

Regulation of feeding behavior, gastrointestinal function and fluid homeostasis by apelin

inferred← citeshttps://doi.org/10.1016/j.peptides.2013.05.013openalex-snapshot

The apelinergic system: Sexual dimorphism and tissue-specific modulations by obesity and insulin resistance in female mice

inferred← citeshttps://doi.org/10.1016/j.peptides.2018.09.006openalex-snapshot

Elabela, a newly discovered APJ ligand: Similarities and differences with Apelin

inferred← citeshttps://doi.org/10.1016/j.peptides.2019.03.006openalex-snapshot

The effect of apelin-13 on pancreatic islet beta cell mass and myocardial fatty acid and glucose metabolism of experimental type 2 diabetic rats

inferred← citeshttps://doi.org/10.1016/j.peptides.2019.170139openalex-snapshot

Apelin-36-[L28A] and Apelin-36-[L28C(30kDa-PEG)] peptides that improve diet induced obesity are G protein biased ligands at the apelin receptor

inferred← citeshttps://doi.org/10.1016/j.peptides.2021.170697openalex-snapshot

Apelin pathway in cardiovascular, kidney, and metabolic diseases: Therapeutic role of apelin analogs and apelin receptor agonists

inferred← citeshttps://doi.org/10.1016/j.pharmthera.2014.09.007openalex-snapshot

An atlas of G-protein coupled receptor expression and function in human subcutaneous adipose tissue

inferred← citeshttps://doi.org/10.1016/j.prostaglandins.2015.07.003openalex-snapshot

Omega-3 fatty acids and adipose tissue function in obesity and metabolic syndrome

inferred← citeshttps://doi.org/10.1016/j.regpep.2008.04.003openalex-snapshot

The transcriptional co-activator PGC-1α up regulates apelin in human and mouse adipocytes

inferred← citeshttps://doi.org/10.1016/j.tcm.2007.09.005openalex-snapshot

The Emerging Role of Adipokines as Mediators of Cardiovascular Function: Physiologic and Clinical Perspectives

inferred← citeshttps://doi.org/10.1016/j.tem.2012.02.005openalex-snapshot

Apelin, a promising target for type 2 diabetes treatment?

inferred← citeshttps://doi.org/10.1016/j.tibs.2009.06.008openalex-snapshot

Adipokines as novel modulators of lipid metabolism

inferred← citeshttps://doi.org/10.1016/j.tips.2009.05.003openalex-snapshot

BAT: a new target for human obesity?

inferred← citeshttps://doi.org/10.1016/j.yfrne.2022.100993openalex-snapshot

Exerkines and long-term synaptic potentiation: Mechanisms of exercise-induced neuroplasticity

inferred← citeshttps://doi.org/10.1016/j.yjmcc.2013.08.001openalex-snapshot

APpEaLINg therapeutic target for obesity cardiomyopathy?

inferred← citeshttps://doi.org/10.1016/j.ymgme.2016.07.012openalex-snapshot

Apelin/APJ system as a therapeutic target in diabetes and its complications

inferred← citeshttps://doi.org/10.1017/s0007114508048307openalex-snapshot

Effects of eicosapentaenoic acid ethyl ester on visfatin and apelin in lean and overweight (cafeteria diet-fed) rats

inferred← citeshttps://doi.org/10.1017/s2040174416000702openalex-snapshot

Maternal undernutrition programs the apelinergic system of adipose tissue in adult male rat offspring

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.0c01448openalex-snapshot

Pyrazole Agonist of the Apelin Receptor Improves Symptoms of Metabolic Syndrome in Mice

inferred← citeshttps://doi.org/10.1038/nrneph.2013.145openalex-snapshot

Obesity-related cardiorenal disease: the benefits of bariatric surgery

inferred← citeshttps://doi.org/10.1038/s41467-025-62870-zopenalex-snapshot

Mechanistic insights into the versatile stoichiometry and biased signaling of the apelin receptor-arrestin complex

inferred← citeshttps://doi.org/10.1038/srep19379openalex-snapshot

Combinatorial Treatment with Apelin-13 Enhances the Therapeutic Efficacy of a Preconditioned Cell-Based Therapy for Peripheral Ischemia

inferred← citeshttps://doi.org/10.1042/bcj20200343openalex-snapshot

Loss of APJ mediated β-arrestin signalling improves high-fat diet induced metabolic dysfunction but does not alter cardiac function in mice

inferred← citeshttps://doi.org/10.1055/s-0033-1351321openalex-snapshot

Hypothalamic Actions of Apelin on Energy Metabolism: New Insight on Glucose Homeostasis and Metabolic Disorders

inferred← citeshttps://doi.org/10.1074/jbc.m115.643817openalex-snapshot

Apelin Enhances Brown Adipogenesis and Browning of White Adipocytes

inferred← citeshttps://doi.org/10.1080/07315724.2009.10719795openalex-snapshot

Effects of High-Fat High-Sucrose Feeding, Energy Restriction, andtrans-10,cis-12 Conjugated Linoleic Acid on Visfatin and Apelin in Hamsters

inferred← citeshttps://doi.org/10.1080/10408398.2016.1262325openalex-snapshot

Is apelin gene expression and concentration affected by dietary intakes? A systematic review

inferred← citeshttps://doi.org/10.1080/13813455.2016.1211709openalex-snapshot

Effects of apelin on reproductive functions: relationship with feeding behavior and energy metabolism

inferred← citeshttps://doi.org/10.1080/13813455.2018.1453521openalex-snapshot

Interactive effects of apelin, renin–angiotensin system and nitric oxide in treatment of obesity-induced type 2 diabetes mellitus in male albino rats

inferred← citeshttps://doi.org/10.1080/14728222.2019.1561871openalex-snapshot

The apelin/APJ system as a therapeutic target in metabolic diseases

inferred← citeshttps://doi.org/10.1080/14728222.2026.2638751openalex-snapshot

The emerging endogenous peptide Apelin 13 in diabetes and its related complications: a narrative review

inferred← citeshttps://doi.org/10.1080/21623945.2018.1442980openalex-snapshot

Fish oil as a potential activator of brown and beige fat thermogenesis

inferred← citeshttps://doi.org/10.1089/ars.2010.3454openalex-snapshot

Central Apelin Controls Glucose Homeostasis via a Nitric Oxide-Dependent Pathway in Mice

inferred← citeshttps://doi.org/10.1093/cvr/cvad171openalex-snapshot

Targeting the apelin system for the treatment of cardiovascular diseases

inferred← citeshttps://doi.org/10.1095/biolreprod.116.141754openalex-snapshot

Apelin (APLN) and Apelin Receptor (APLNR) in Human Ovary: Expression, Signaling, and Regulation of Steroidogenesis in Primary Human Luteinized Granulosa Cells

inferred← citeshttps://doi.org/10.1097/crd.0b013e3181b3fe0dopenalex-snapshot

The Emerging Role of Apelin in Cardiovascular Disease and Health

inferred← citeshttps://doi.org/10.1097/hjh.0b013e32832a3eb1openalex-snapshot

Family-based analysis of apelin and AGTRL1 gene polymorphisms with hypertension in Han Chinese

inferred← citeshttps://doi.org/10.1097/hjh.0b013e32833b1fadopenalex-snapshot

Validation of genetic association in apelin–AGTRL1 system with hypertension in a larger Han Chinese population

inferred← citeshttps://doi.org/10.1097/mco.0b013e3282f0dbe4openalex-snapshot

Mitochondrial uncoupling as a target in the treatment of obesity

inferred← citeshttps://doi.org/10.1097/wnr.0000000000000431openalex-snapshot

Central action of ELABELA reduces food intake and activates arginine vasopressin and corticotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus

inferred← citeshttps://doi.org/10.1111/are.14447openalex-snapshot

Apelin and apj in common carp ( Cyprinus carpio L.): Molecular characterization, tissue expression and responses to periprandial changes and fasting–refeeding

inferred← citeshttps://doi.org/10.1111/j.1365-2826.2008.01815.xopenalex-snapshot

Diminished Metabolic Responses to Centrally‐Administered Apelin‐13 in Diet‐Induced Obese Rats Fed a High‐Fat Diet

inferred← citeshttps://doi.org/10.1111/j.1467-789x.2011.00914.xopenalex-snapshot

Mechanisms linking obesity to hypertension

inferred← citeshttps://doi.org/10.1111/j.1748-1716.2010.02171.xopenalex-snapshot

Role of adipokines in obesity‐associated hypertension

inferred← citeshttps://doi.org/10.1111/j.1753-0407.2011.00132.xopenalex-snapshot

Apelin and insulin resistance: Another arrow for the quiver?

inferred← citeshttps://doi.org/10.1111/jpn.12240openalex-snapshot

Comparatively examining of the apelin‐13 levels in the Capoeta trutta (Heckel, 1843) and Cyprinus carpio (Linnaeus, 1758)

inferred← citeshttps://doi.org/10.1113/ep089182openalex-snapshot

The role of autonomic pathways in peripheral apelin‐induced gastrointestinal dysmotility: involvement of the circumventricular organs

inferred← citeshttps://doi.org/10.1113/jp284552openalex-snapshot

Exercise improves homeostasis of the intestinal epithelium by activation of apelin receptor–AMP‐activated protein kinase signalling

inferred← citeshttps://doi.org/10.1124/pr.110.002949openalex-snapshot

International Union of Basic and Clinical Pharmacology. LXXIV. Apelin Receptor Nomenclature, Distribution, Pharmacology, and Function

inferred← citeshttps://doi.org/10.1134/s0006297923110160openalex-snapshot

Apelin C-Terminal Fragments: Biological Properties and Therapeutic Potential

inferred← citeshttps://doi.org/10.1134/s1022795408100050openalex-snapshot

Adipokine genetics: Unbalanced protein secretion by human adipose tissue as a cause of the metabolic syndrome

inferred← citeshttps://doi.org/10.1152/ajpendo.00385.2009openalex-snapshot

Apelin is necessary for the maintenance of insulin sensitivity

inferred← citeshttps://doi.org/10.1152/ajpheart.00449.2019openalex-snapshot

Exacerbated pressor and sympathoexcitatory effects of central Elabela in spontaneously hypertensive rats

inferred← citeshttps://doi.org/10.1152/ajpregu.00422.2009openalex-snapshot

The effects of apelin treatment on skeletal muscle mitochondrial content

inferred← citeshttps://doi.org/10.1155/2010/535918openalex-snapshot

Inflammation, a Link between Obesity and Cardiovascular Disease

inferred← citeshttps://doi.org/10.1155/2012/917496openalex-snapshot

Associations of Common Variants atAPLNand Hypertension in Chinese Subjects with and without Diabetes

inferred← citeshttps://doi.org/10.1155/2016/7030795openalex-snapshot

The Microbial Hypothesis: Contributions of Adenovirus Infection and Metabolic Endotoxaemia to the Pathogenesis of Obesity

inferred← citeshttps://doi.org/10.1155/2018/9170480openalex-snapshot

Apelin in Reproductive Physiology and Pathology of Different Species: A Critical Review

inferred← citeshttps://doi.org/10.1155/2021/5570331openalex-snapshot

Effect of Omega‐3 or Omega‐6 Dietary Supplementation on Testicular Steroidogenesis, Adipokine Network, Cytokines, and Oxidative Stress in Adult Male Rats

inferred← citeshttps://doi.org/10.1159/000526961openalex-snapshot

Is Habitual Dietary Intake of Fats Associated with Apelin Gene Expression in Visceral and Subcutaneous Adipose Tissues and Its Serum Levels in Obese Adults?

inferred← citeshttps://doi.org/10.1161/hypertensionaha.109.134619openalex-snapshot

[Pyr 1 ]Apelin-13 Identified as the Predominant Apelin Isoform in the Human Heart

inferred← citeshttps://doi.org/10.1177/0003319713520463openalex-snapshot

Adipokines, Vascular Wall, and Cardiovascular Disease

inferred← citeshttps://doi.org/10.1177/20587392211042443openalex-snapshot

Apelin: A new biomarker in fatty liver disease

inferred← citeshttps://doi.org/10.1186/1741-7015-9-25openalex-snapshot

Regulation of vascular tone by adipocytes

inferred← citeshttps://doi.org/10.1186/s13287-018-1084-xopenalex-snapshot

Overexpression of apelin in Wharton’ jelly mesenchymal stem cell reverses insulin resistance and promotes pancreatic β cell proliferation in type 2 diabetic rats

inferred← citeshttps://doi.org/10.1210/en.2010-0576openalex-snapshot

Apelin Decreases Lipolysis via Gq, Gi, and AMPK-Dependent Mechanisms

inferred← citeshttps://doi.org/10.1210/en.2014-1631openalex-snapshot

Pancreatic Islet APJ Deletion Reduces Islet Density and Glucose Tolerance in Mice

inferred← citeshttps://doi.org/10.12659/msm.890124openalex-snapshot

Apelin-13 Decreases Lipid Storage in Hypertrophic Adipocytes In Vitro Through the Upregulation of AQP7 Expression by the PI3K Signaling Pathway

inferred← citeshttps://doi.org/10.12677/acm.2024.1492506openalex-snapshot

Advances in the Study of Adipokine Apelin and Pathogenesis of Gestational Diabetes Mellitus

inferred← citeshttps://doi.org/10.1371/annotation/15dd6d58-5cea-4252-94a6-52778c6ee55eopenalex-snapshot

Correction: Apelin Ameliorates TNF-α-Induced Reduction of Glycogen Synthesis in the Hepatocytes through G Protein-Coupled Receptor APJ

inferred← citeshttps://doi.org/10.1371/journal.pone.0057231openalex-snapshot

Apelin Ameliorates TNF-α-Induced Reduction of Glycogen Synthesis in the Hepatocytes through G Protein-Coupled Receptor APJ

inferred← citeshttps://doi.org/10.1371/journal.pone.0063918openalex-snapshot

Resveratrol Metabolites Modify Adipokine Expression and Secretion in 3T3-L1 Pre-Adipocytes and Mature Adipocytes

inferred← citeshttps://doi.org/10.1371/journal.pone.0197603openalex-snapshot

Prolyl carboxypeptidase activity in the circulation and its correlation with body weight and adipose tissue in lean and obese subjects

inferred← citeshttps://doi.org/10.1371/journal.pone.0202350openalex-snapshot

Long-term treatment with acylated analogues of apelin-13 amide ameliorates diabetes and improves lipid profile of high-fat fed mice

inferred← citeshttps://doi.org/10.1371/journal.pone.0231844openalex-snapshot

Increased apelin receptor gene expression in the subfornical organ of spontaneously hypertensive rats

inferred← citeshttps://doi.org/10.1371/journal.pone.0238784openalex-snapshot

Expression characteristics and regulatory mechanism of Apela gene in liver of chicken (Gallus gallus)

inferred← citeshttps://doi.org/10.14310/horm.2002.1376openalex-snapshot

Differences in plasma apelin and visfatin levels between patients with type 1 diabetes mellitus and healthy subjects and response after acute hyperglycemia and insulin administration

inferred← citeshttps://doi.org/10.14814/phy2.13450openalex-snapshot

Dietary weight loss‐induced changes in RBP 4, FFA , and ACE predict weight regain in people with overweight and obesity

inferred← citeshttps://doi.org/10.1507/endocrj.k10e-221openalex-snapshot

The effects of branched-chain amino acid granules on the accumulation of tissue triglycerides and uncoupling proteins in diet-induced obese mice

inferred← citeshttps://doi.org/10.1517/14728221003752743openalex-snapshot

The apelinergic system: a promising therapeutic target

inferred← citeshttps://doi.org/10.1517/14728222.2014.882321openalex-snapshot

Biomarkers in the field of obesity and its related comorbidities

inferred← citeshttps://doi.org/10.1517/17460441.2011.571251openalex-snapshot

Update on apelin peptides as putative targets for cardiovascular drug discovery

inferred← citeshttps://doi.org/10.1517/17460441.3.1.51openalex-snapshot

The apelin peptides as putative targets in cardiovascular drug discovery and development

inferred← citeshttps://doi.org/10.1530/joe-12-0232openalex-snapshot

Role of adipokines in cardiovascular disease

inferred← citeshttps://doi.org/10.1530/joe-13-0227openalex-snapshot

The apelin receptor APJ: journey from an orphan to a multifaceted regulator of homeostasis

inferred← citeshttps://doi.org/10.15406/emij.2015.02.00018openalex-snapshot

Omentin and Apelin Concentrations in Relation to Obesity Diabetes Mellitus Type two and Cardiovascular Diseases in Egyptiant Population

inferred← citeshttps://doi.org/10.1586/14779072.2014.911661openalex-snapshot

Apelin receptor: its responsiveness to stretch mechanisms and its potential for cardiovascular therapy

inferred← citeshttps://doi.org/10.1590/1414-431x20132911openalex-snapshot

New concepts in white adipose tissue physiology

inferred← citeshttps://doi.org/10.1590/s0066-782x2008000500012openalex-snapshot

O sistema apelinérgico: papel na fisiologia e patologia humanas e potenciais aplicações terapêuticas

inferred← citeshttps://doi.org/10.1677/jme-10-0105openalex-snapshot

Apelin stimulates glucose uptake but not lipolysis in human adipose tissue ex vivo

inferred← citeshttps://doi.org/10.18203/2320-6012.ijrms20223078openalex-snapshot

Analysis and establish a correlation between serum ceruloplasmin, serum apelin level and thyroid profile in patients with hypothyroidism and healthy controls

inferred← citeshttps://doi.org/10.18233/apm43no4pp221-2292236openalex-snapshot

The relationship between maternal serum apelin-36 level and anthropometric indices up to 18 months after birth; A cohort Study

inferred← citeshttps://doi.org/10.18632/oncotarget.24111openalex-snapshot

Association study of apelin-APJ system genetic polymorphisms with incident metabolic syndrome in a Chinese population: a case-control study

inferred← citeshttps://doi.org/10.21608/ejhm.2022.227708openalex-snapshot

Cross-Talk between Apelin, Insulin Resistance, Thyroid Hormones, and Cardio-metabolic Risk Factors in Polycystic Ovary Syndrome

inferred← citeshttps://doi.org/10.21608/mjcu.2019.53565openalex-snapshot

Lipolytic Effects of Testosterone Hormone Replacement Therapy in A Rat Model of Andropause Versus Normal Controls

inferred← citeshttps://doi.org/10.21608/zumj.2013.4297openalex-snapshot

EFFECT OF APELIN-13 ADMINISTRATION ON GASTRIC SECRETION IN NORMAL AND DIABETIC RATS

inferred← citeshttps://doi.org/10.21608/zumj.2013.4308openalex-snapshot

IS APELIN A PROMISING TARGET IN DIABETES MELLITUS OF RATS: TYPE I VS. TYPE II?

inferred← citeshttps://doi.org/10.2174/011573403x332671241121063641openalex-snapshot

Molecular and Functional Significance of Growth Differentiation Factor-15: A Review on Cardiovascular-Kidney-Metabolic Biomarker

inferred← citeshttps://doi.org/10.21859/ijnr-13016openalex-snapshot

Effects of two Exercise Modalities of Sprint Interval Training and Combined Training (Strength-Aerobic) on Serum Apelin levels and Insulin Resistance in Women with Type 2 Diabetes

inferred← citeshttps://doi.org/10.22141/2224-0721.4.60.2014.76689openalex-snapshot

Роль апеліну у розвитку глюкометаболічних порушень (огляд літератури та власних досліджень)

inferred← citeshttps://doi.org/10.2218/gtopdb/f7/2019.4openalex-snapshot

Apelin receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

inferred← citeshttps://doi.org/10.2218/gtopdb/f7/2023.1openalex-snapshot

Apelin receptor in GtoPdb v.2023.1

inferred← citeshttps://doi.org/10.22358/jafs/65576/2016openalex-snapshot

The apelin-13 influences the activity of pancreatic enzymes in young rats

inferred← citeshttps://doi.org/10.22514/jomh.2024.027openalex-snapshot

Effects of acute and chronic high-intensity interval training on serum irisin, BDNF and apelin levels in male soccer referees

inferred← citeshttps://doi.org/10.2337/db11-0100openalex-snapshot

Apelin Treatment Increases Complete Fatty Acid Oxidation, Mitochondrial Oxidative Capacity, and Biogenesis in Muscle of Insulin-Resistant Mice

inferred← citeshttps://doi.org/10.2478/amb-2025-0046openalex-snapshot

Systemic Nitric Oxide Synthase Inhibition Suppresses Apelin-Induced Rise in Body Temperature in Rats

inferred← citeshttps://doi.org/10.25130/tjps.v21i7.1118openalex-snapshot

Study the relationship between Apelin and some biochemical parameters in patients with kidney diseases

inferred← citeshttps://doi.org/10.25560/11607openalex-snapshot

The Genetic Mechanisms Underlying Human Obesity

inferred← citeshttps://doi.org/10.2741/3807openalex-snapshot

Brown adipose tissue growth and development: significance and nutritional regulation

inferred← citeshttps://doi.org/10.31031/gjem.1.1openalex-snapshot

inferred← citeshttps://doi.org/10.31031/gjem.2017.01.000501openalex-snapshot

Apelin and Sirtuin 1 Dysregulation induce Endocrine and Metabolic Disorders in Chronic Disease

inferred← citeshttps://doi.org/10.3109/0886022x.2012.668490openalex-snapshot

Apelin: A Peptide Involved in Cardiovascular Risk in Hemodialysis Patients?

inferred← citeshttps://doi.org/10.3109/10641963.2013.764889openalex-snapshot

Apelin Effects on Blood Pressure and RAS in DOCA-Salt-Induced Hypertensive Rats

inferred← citeshttps://doi.org/10.31857/s0320972523110179openalex-snapshot

Apelin C-terminal fragments: biological properties and therapeutic potential

inferred← citeshttps://doi.org/10.32657/10356/50751openalex-snapshot

Study of adipokine secretion and their functions

inferred← citeshttps://doi.org/10.3389/fendo.2023.1193150openalex-snapshot

The role of apelinergic system in metabolism and reproductive system in normal and pathological conditions: an overview

inferred← citeshttps://doi.org/10.3389/fphys.2015.00115openalex-snapshot

Apelin and energy metabolism

inferred← citeshttps://doi.org/10.3389/fphys.2021.632886openalex-snapshot

The Role of Apelin/Apelin Receptor in Energy Metabolism and Water Homeostasis: A Comprehensive Narrative Review

inferred← citeshttps://doi.org/10.3389/fphys.2021.711041openalex-snapshot

Circumventricular Organ Apelin Receptor Knockdown Decreases Blood Pressure and Sympathetic Drive Responses in the Spontaneously Hypertensive Rat

inferred← citeshttps://doi.org/10.3389/fvets.2025.1592068openalex-snapshot

Integrated genomic and transcriptomic analysis of polydactyly in chickens

inferred← citeshttps://doi.org/10.3390/biom14101241openalex-snapshot

Exercise, Neuroprotective Exerkines, and Parkinson’s Disease: A Narrative Review

inferred← citeshttps://doi.org/10.3390/cancers14071679openalex-snapshot

Thromboinflammatory Processes at the Nexus of Metabolic Dysfunction and Prostate Cancer: The Emerging Role of Periprostatic Adipose Tissue

inferred← citeshttps://doi.org/10.3390/cancers14071814openalex-snapshot

Apelin Resistance Contributes to Muscle Loss during Cancer Cachexia in Mice

inferred← citeshttps://doi.org/10.3390/cells11213361openalex-snapshot

The Role of Crosstalk between Adipose Cells and Myocytes in the Pathogenesis of Sarcopenic Obesity in the Elderly

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