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Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/dvdy.20729openalex-snapshot
Osteopontin is a novel marker of pancreatic ductal tissues and of undifferentiated pancreatic precursors in mice
inferredcites →https://doi.org/10.1002/dvg.20397openalex-snapshot
A CK19CreERT knockin mouse line allows for conditional DNA recombination in epithelial cells in multiple endodermal organs
inferredcites →https://doi.org/10.1002/stem.482openalex-snapshot
Pancreatic β-Cell Neogenesis by Direct Conversion from Mature α-Cells
inferredcites →https://doi.org/10.1007/bf00400600openalex-snapshot
Duct- to islet-cell differentiation and islet growth in the pancreas of duct-ligated adult rats
inferredcites →https://doi.org/10.1007/bf00403301openalex-snapshot
Beta-cell growth in adolescent and adult rats treated with streptozotocin during the neonatal period
inferredcites →https://doi.org/10.1016/j.cell.2007.12.015openalex-snapshot
β Cells Can Be Generated from Endogenous Progenitors in Injured Adult Mouse Pancreas
inferredcites →https://doi.org/10.1016/j.cmet.2009.12.005openalex-snapshot
Ductal Origin Hypothesis of Pancreatic Regeneration under Attack
inferredcites →https://doi.org/10.1016/j.cub.2005.06.064openalex-snapshot
Sox9 Is Essential for Outer Root Sheath Differentiation and the Formation of the Hair Stem Cell Compartment
inferredcites →https://doi.org/10.1016/j.devcel.2007.06.001openalex-snapshot
A Multipotent Progenitor Domain Guides Pancreatic Organogenesis
inferredcites →https://doi.org/10.1016/j.devcel.2009.11.003openalex-snapshot
Pancreatic Exocrine Duct Cells Give Rise to Insulin-Producing β Cells during Embryogenesis but Not after Birth
inferredcites →https://doi.org/10.1016/j.devcel.2010.05.015openalex-snapshot
Nkx6 Transcription Factors and Ptf1a Function as Antagonistic Lineage Determinants in Multipotent Pancreatic Progenitors
inferredcites →https://doi.org/10.1016/j.ydbio.2008.07.034openalex-snapshot
A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation
inferredcites →https://doi.org/10.1038/5007openalex-snapshot
Generalized lacZ expression with the ROSA26 Cre reporter strain
inferredcites →https://doi.org/10.1038/nature02520openalex-snapshot
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
inferredcites →https://doi.org/10.1038/ng959openalex-snapshot
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
inferredcites →https://doi.org/10.1073/pnas.0504750102openalex-snapshot
Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors
inferredcites →https://doi.org/10.1073/pnas.0609217104openalex-snapshot
SOX9 is required for maintenance of the pancreatic progenitor cell pool
inferredcites →https://doi.org/10.1073/pnas.0805803105openalex-snapshot
Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth
inferredcites →https://doi.org/10.1073/pnas.0904247106openalex-snapshot
Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function
inferredcites →https://doi.org/10.1073/pnas.0912589107openalex-snapshot
Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas
inferredcites →https://doi.org/10.1093/nar/29.9.e45openalex-snapshot
A new mathematical model for relative quantification in real-time RT-PCR
inferredcites →https://doi.org/10.1097/00000658-198908000-00003openalex-snapshot
Pancreatic Structure and Glucose Tolerance in a Longitudinal Study of Experimental Pancreatitis-Induced Diabetes
inferredcites →https://doi.org/10.1097/01.mpa.0000236734.39241.99openalex-snapshot
Establishment of Animal Models for Three Types of Pancreatitis and Analyses of Regeneration Mechanisms
inferredcites →https://doi.org/10.1111/j.1469-7580.2004.00265.xopenalex-snapshot
Fission of pancreatic islets during postnatal growth of the mouse
inferredcites →https://doi.org/10.1186/1471-213x-1-4openalex-snapshot
Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
inferredcites →https://doi.org/10.1186/1471-213x-10-38openalex-snapshot
Exocrine-to-endocrine differentiation is detectable only prior to birth in the uninjured mouse pancreas
inferredcites →https://doi.org/10.1242/dev.00808openalex-snapshot
Neural crest development is regulated by the transcription factor Sox9
inferredcites →https://doi.org/10.1242/dev.01875openalex-snapshot
NKX6 transcription factor activity is required for α- andβ-cell development in the pancreas
inferredcites →https://doi.org/10.1242/dev.048421openalex-snapshot
Adult pancreatic acinar cells give rise to ducts but not endocrine cells in response to growth factor signaling
inferredcites →https://doi.org/10.1242/dev.118.1.33openalex-snapshot
Epithelial cell proliferation and islet neogenesis in IFN-g transgenic mice
inferredcites →https://doi.org/10.1242/dev.129.10.2447openalex-snapshot
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
inferredcites →https://doi.org/10.1371/journal.pone.0004815openalex-snapshot
A GRFa2/Prop1/Stem (GPS) Cell Niche in the Pituitary
inferredcites →https://doi.org/10.2337/diabetes.48.12.2270openalex-snapshot
Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats.
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4789208openalex-extracted
Unlocking Regenerative Potential: Beta-Cell Neogenesis and Novel Myokines Involved in Adaptation to Insulin Resistance in Mice
inferred← citeshttps://doi.org/10.1002/ar.22420openalex-snapshot
Whole‐Mount Imaging Demonstrates Hypervascularity of the Pancreatic Ducts and Other Pancreatic Structures
inferred← citeshttps://doi.org/10.1002/bies.201800119openalex-snapshot
Evidence for a Neogenic Niche at the Periphery of Pancreatic Islets
inferred← citeshttps://doi.org/10.1002/bies.202300083openalex-snapshot
Lung patterning: Is a distal‐to‐proximal gradient of cell allocation and fate decision a general paradigm?
inferred← citeshttps://doi.org/10.1002/ctm2.1052openalex-snapshot
The heterogeneity of mammalian utricular cells over the course of development
inferred← citeshttps://doi.org/10.1002/dvdy.23781openalex-snapshot
EphB3 marks delaminating endocrine progenitor cells in the developing pancreas
inferred← citeshttps://doi.org/10.1002/dvdy.24626openalex-snapshot
ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis
inferred← citeshttps://doi.org/10.1002/dvdy.70063openalex-snapshot
Streptozotocin induced hyperglycemia in the axolotl
inferred← citeshttps://doi.org/10.1002/dvg.22384openalex-snapshot
Non‐parallel recombination limits cre‐loxP‐based reporters as precise indicators of conditional genetic manipulation
inferred← citeshttps://doi.org/10.1002/dvg.23211openalex-snapshot
Salivary gland stem cells: A review of development, regeneration and cancer
inferred← citeshttps://doi.org/10.1002/hep.27084openalex-snapshot
Clonal Tracing of Sox9+ Liver Progenitors in Mouse Oval Cell Injury
inferred← citeshttps://doi.org/10.1002/jor.24122openalex-snapshot
Genetic lineage tracing of targeted cell populations during enthesis healing
inferred← citeshttps://doi.org/10.1002/path.4015openalex-snapshot
Activation of protein kinase Cδ leads to increased pancreatic acinar cell dedifferentiation in the absence of MIST1
inferred← citeshttps://doi.org/10.1002/path.5629openalex-snapshot
Insights into the etiology and physiopathology of MODY5 / HNF1B pancreatic phenotype with a mouse model of the human disease
inferred← citeshttps://doi.org/10.1002/path.5883openalex-snapshot
Clinical significance of pancreatic ductal metaplasia
inferred← citeshttps://doi.org/10.1002/stem.1828openalex-snapshot
Concise Reviews: In Vitro-Produced Pancreas Organogenesis Models in Three Dimensions: Self-Organization From Few Stem Cells or Progenitors
inferred← citeshttps://doi.org/10.1002/wdev.44openalex-snapshot
The endocrine pancreas: insights into development, differentiation, and diabetes
inferred← citeshttps://doi.org/10.1002/wdev.99openalex-snapshot
Notch signaling in the pancreas: patterning and cell fate specification
inferred← citeshttps://doi.org/10.1007/5584_2022_756openalex-snapshot
Direct Reprogramming of Somatic Cells into Induced β-Cells: An Overview
inferred← citeshttps://doi.org/10.1007/978-1-0716-1119-7_3openalex-snapshot
Cartilage-Specific Cre Recombinase Transgenes/Alleles in the Mouse
inferred← citeshttps://doi.org/10.1007/978-1-0716-3139-3_15openalex-snapshot
Defining Gene Function in Spermatogonial Stem Cells Through Conditional Knockout Approaches
inferred← citeshttps://doi.org/10.1007/978-1-4614-7696-2_20openalex-snapshot
Progenitors of Islet Cells
inferred← citeshttps://doi.org/10.1007/978-1-4939-6631-8_4-2openalex-snapshot
Developmental Molecular Biology of the Pancreas
inferred← citeshttps://doi.org/10.1007/978-1-4939-7193-0_4openalex-snapshot
Developmental Molecular Biology of the Pancreas
inferred← citeshttps://doi.org/10.1007/978-1-4939-8961-4_5openalex-snapshot
Genetic Lineage Tracing of Biliary Epithelial Cells
inferred← citeshttps://doi.org/10.1007/978-1-4939-8961-4_6openalex-snapshot
Specific Labeling and Lineage Tracing of Periportal Hepatocytes Using Two-Step Genetic Recombination
inferred← citeshttps://doi.org/10.1007/978-1-4939-9631-5_6openalex-snapshot
Isolation and Characterization of Colony-Forming Progenitor Cells from Adult Pancreas
inferred← citeshttps://doi.org/10.1007/978-1-62703-068-7_20openalex-snapshot
Lineage Tracing of Pancreatic Stem Cells and Beta Cell Regeneration
inferred← citeshttps://doi.org/10.1007/978-1-62703-098-4_9openalex-snapshot
Pancreatic Regeneration in the Face of Diabetes
inferred← citeshttps://doi.org/10.1007/978-3-031-62232-8_2openalex-snapshot
Development of the Pancreatic Ducts and Their Contribution to Organogenesis
inferred← citeshttps://doi.org/10.1007/978-3-031-62232-8_3openalex-snapshot
β-Cell Heterogeneity and Plasticity
inferred← citeshttps://doi.org/10.1007/978-3-031-62232-8_4openalex-snapshot
β-Cell Regeneration Is Driven by Pancreatic Plasticity
inferred← citeshttps://doi.org/10.1007/978-3-319-21705-5_6openalex-snapshot
The Elusive Pancreatic Stem Cell
inferred← citeshttps://doi.org/10.1007/978-3-319-57153-9_10openalex-snapshot
Engineering Organoid Systems to Model Health and Disease
inferred← citeshttps://doi.org/10.1007/978-3-319-90695-9_9openalex-snapshot
Regenerative Medicine for Diabetes Treatment: New β-Cell Sources
inferred← citeshttps://doi.org/10.1007/978-81-322-2110-4_14openalex-snapshot
Overview of Pancreatic Replacement of β-Cells from Various Cell Sources
inferred← citeshttps://doi.org/10.1007/978-94-007-6686-0_36openalex-snapshot
Regulation of Pancreatic Islet Formation
inferred← citeshttps://doi.org/10.1007/978-94-007-6884-0_36-2openalex-snapshot
Regulation of Pancreatic Islet Formation
inferred← citeshttps://doi.org/10.1007/s00018-013-1510-2openalex-snapshot
Transcriptional control of mammalian pancreas organogenesis
inferred← citeshttps://doi.org/10.1007/s00125-014-3179-yopenalex-snapshot
Pancreatic duct cells as a source of VEGF in mice
inferred← citeshttps://doi.org/10.1007/s00125-016-3922-7openalex-snapshot
Extreme obesity induces massive beta cell expansion in mice through self-renewal and does not alter the beta cell lineage
inferred← citeshttps://doi.org/10.1007/s00125-016-4023-3openalex-snapshot
A combination of cytokines EGF and CNTF protects the functional beta cell mass in mice with short-term hyperglycaemia
inferred← citeshttps://doi.org/10.1007/s00418-014-1248-4openalex-snapshot
Proliferating pancreatic beta-cells upregulate ALDH
inferred← citeshttps://doi.org/10.1007/s00595-017-1501-2openalex-snapshot
Cells of origin of pancreatic neoplasms
inferred← citeshttps://doi.org/10.1007/s10162-012-0324-5openalex-snapshot
Conditional Gene Expression in the Mouse Inner Ear Using Cre-loxP
inferred← citeshttps://doi.org/10.1007/s10162-018-0676-6openalex-snapshot
Characterization of Adult Vestibular Organs in 11 CreER Mouse Lines
inferred← citeshttps://doi.org/10.1007/s10735-024-10328-9openalex-snapshot
Effects of FGFR2b-ligand signaling on pancreatic branching morphogenesis and postnatal islet function
inferred← citeshttps://doi.org/10.1007/s11033-026-12376-8openalex-snapshot
Integrated transcriptomic and proteomic analysis reveals isolation and culture associated molecular changes in neonatal porcine pancreatic cell clusters
inferred← citeshttps://doi.org/10.1007/s11427-021-2007-8openalex-snapshot
Recent advances in tissue stem cells
inferred← citeshttps://doi.org/10.1007/s11626-012-9555-3openalex-snapshot
Induction of mouse pancreatic ductal differentiation, an in vitro assay
inferred← citeshttps://doi.org/10.1007/s11892-011-0218-7openalex-snapshot
Potential Pathways to Restore β-Cell Mass: Pluripotent Stem Cells, Reprogramming, and Endogenous Regeneration
inferred← citeshttps://doi.org/10.1007/s11892-012-0301-8openalex-snapshot
Understanding Pancreas Development for β-Cell Repair and Replacement Therapies
inferred← citeshttps://doi.org/10.1007/s11892-013-0400-1openalex-snapshot
Making β Cells from Adult Cells Within the Pancreas
inferred← citeshttps://doi.org/10.1007/s11892-016-0729-3openalex-snapshot
New Insights into Diabetes Cell Therapy
inferred← citeshttps://doi.org/10.1007/s11892-019-1261-zopenalex-snapshot
Organoids from the Human Fetal and Adult Pancreas
inferred← citeshttps://doi.org/10.1007/s12015-011-9346-3openalex-snapshot
Directed Differentiation of Embryonic Stem Cells Allows Exploration of Novel Transcription Factor Genes for Pancreas Development
inferred← citeshttps://doi.org/10.1007/s12015-021-10232-9openalex-snapshot
New hPSC SOX9 and INS Reporter Cell Lines Facilitate the Observation and Optimization of Differentiation into Insulin-Producing Cells
inferred← citeshttps://doi.org/10.1007/s12015-025-10859-yopenalex-snapshot
Pancreatic Ductal Cell Heterogeneity: Insights into the Potential for β-Cell Regeneration in Diabetes
inferred← citeshttps://doi.org/10.1007/s12022-015-9362-yopenalex-snapshot
Mesenchymal Stem Cells in the Treatment of Type 1 Diabetes Mellitus
inferred← citeshttps://doi.org/10.1007/s13340-024-00774-xopenalex-snapshot
Differentiation, reduction, and proliferation of pancreatic β-cells and their regulatory factors
inferred← citeshttps://doi.org/10.1007/s13402-022-00664-xopenalex-snapshot
Molecular signaling in pancreatic ductal metaplasia: emerging biomarkers for detection and intervention of early pancreatic cancer
inferred← citeshttps://doi.org/10.1007/s40139-015-0068-0openalex-snapshot
Direct Reprogramming for Pancreatic Beta-Cells Using Key Developmental Genes
inferred← citeshttps://doi.org/10.1007/s40139-016-0097-3openalex-snapshot
The Role of IL-17 Signaling in Regulation of the Liver–Brain Axis and Intestinal Permeability in Alcoholic Liver Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-386456-7.04901-7openalex-snapshot
Normal Pancreatic Development
inferred← citeshttps://doi.org/10.1016/b978-0-12-405945-0.00031-4openalex-snapshot
Pancreas Development and Regeneration
inferred← citeshttps://doi.org/10.1016/b978-0-12-416012-5.00010-4openalex-snapshot
Liver Resident Stem Cell
inferred← citeshttps://doi.org/10.1016/b978-0-12-814831-0.00013-0openalex-snapshot
Human pancreatic progenitors
inferred← citeshttps://doi.org/10.1016/b978-0-12-814831-0.00029-4openalex-snapshot
Ductal cell reprograming to insulin-producing cells as a potential beta cell replacement source for islet auto-transplant recipients
inferred← citeshttps://doi.org/10.1016/b978-0-443-15289-4.00015-9openalex-snapshot
Resident Liver Stem Cells
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2016.10.005openalex-snapshot
Zebrafish Pancreas Development and Regeneration
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2018.02.009openalex-snapshot
Recapitulating and Deciphering Human Pancreas Development From Human Pluripotent Stem Cells in a Dish
inferred← citeshttps://doi.org/10.1016/j.ajpath.2015.08.006openalex-snapshot
Valproic Acid Limits Pancreatic Recovery after Pancreatitis by Inhibiting Histone Deacetylases and Preventing Acinar Redifferentiation Programs
inferred← citeshttps://doi.org/10.1016/j.bbcan.2022.188698openalex-snapshot
Ductal metaplasia in pancreas
inferred← citeshttps://doi.org/10.1016/j.beem.2015.10.001openalex-snapshot
Reprogramming of human exocrine pancreas cells to beta cells
inferred← citeshttps://doi.org/10.1016/j.biocel.2017.03.005openalex-snapshot
SOX9: A genomic view of tissue specific expression and action
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2020.120201openalex-snapshot
Sweat gland regeneration: Current strategies and future opportunities
inferred← citeshttps://doi.org/10.1016/j.ccr.2012.10.025openalex-snapshot
Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma
inferred← citeshttps://doi.org/10.1016/j.ceb.2017.11.014openalex-snapshot
Phenotypic plasticity in the pancreas: new triggers, new players
inferred← citeshttps://doi.org/10.1016/j.cell.2012.02.008openalex-snapshot
Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State
inferred← citeshttps://doi.org/10.1016/j.cell.2020.02.048openalex-snapshot
Long-Term Expansion of Pancreatic Islet Organoids from Resident Procr+ Progenitors
inferred← citeshttps://doi.org/10.1016/j.cell.2024.10.044openalex-snapshot
Long-term in vitro expansion of a human fetal pancreas stem cell that generates all three pancreatic cell lineages
inferred← citeshttps://doi.org/10.1016/j.celrep.2012.10.016openalex-snapshot
Planar Cell Polarity Controls Pancreatic Beta Cell Differentiation and Glucose Homeostasis
inferred← citeshttps://doi.org/10.1016/j.celrep.2015.08.082openalex-snapshot
A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells
inferred← citeshttps://doi.org/10.1016/j.celrep.2016.03.036openalex-snapshot
Proinflammatory Cytokines Induce Endocrine Differentiation in Pancreatic Ductal Cells via STAT3-Dependent NGN3 Activation
inferred← citeshttps://doi.org/10.1016/j.celrep.2017.02.071openalex-snapshot
Lineage-Biased Stem Cells Maintain Estrogen-Receptor-Positive and -Negative Mouse Mammary Luminal Lineages
inferred← citeshttps://doi.org/10.1016/j.celrep.2017.03.032openalex-snapshot
Efficient Generation of Glucose-Responsive Beta Cells from Isolated GP2+ Human Pancreatic Progenitors
inferred← citeshttps://doi.org/10.1016/j.celrep.2018.11.078openalex-snapshot
Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA
inferred← citeshttps://doi.org/10.1016/j.celrep.2019.01.063openalex-snapshot
PyMINEr Finds Gene and Autocrine-Paracrine Networks from Human Islet scRNA-Seq
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.110377openalex-snapshot
Adult pancreatic islet endocrine cells emerge as fetal hormone-expressing cells
inferred← citeshttps://doi.org/10.1016/j.cmet.2013.06.011openalex-snapshot
Pancreas-Specific Cre Driver Lines and Considerations for Their Prudent Use
inferred← citeshttps://doi.org/10.1016/j.cmet.2017.08.007openalex-snapshot
Pancreatic β Cell Regeneration as a Possible Therapy for Diabetes
inferred← citeshttps://doi.org/10.1016/j.cophys.2019.10.019openalex-snapshot
Pancreatic β cell regeneration: to β or not to β
inferred← citeshttps://doi.org/10.1016/j.cub.2013.05.037openalex-snapshot
Metabolic Regulation of Cellular Plasticity in the Pancreas
inferred← citeshttps://doi.org/10.1016/j.devcel.2013.03.016openalex-snapshot
Gene Regulatory Networks Governing Pancreas Development
inferred← citeshttps://doi.org/10.1016/j.devcel.2016.10.002openalex-snapshot
Single-Cell Analysis Uncovers Clonal Acinar Cell Heterogeneity in the Adult Pancreas
inferred← citeshttps://doi.org/10.1016/j.devcel.2018.05.027openalex-snapshot
EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration
inferred← citeshttps://doi.org/10.1016/j.devcel.2018.06.028openalex-snapshot
Defining Lineage Potential and Fate Behavior of Precursors during Pancreas Development
inferred← citeshttps://doi.org/10.1016/j.devcel.2018.11.048openalex-snapshot
Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity
inferred← citeshttps://doi.org/10.1016/j.devcel.2020.01.015openalex-snapshot
Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors
inferred← citeshttps://doi.org/10.1016/j.diff.2015.10.008openalex-snapshot
Islet Neogenesis Associated Protein (INGAP) induces the differentiation of an adult human pancreatic ductal cell line into insulin-expressing cells through stepwise activation of key transcription factors for embryonic beta cell development
inferred← citeshttps://doi.org/10.1016/j.diff.2016.02.001openalex-snapshot
Role of β-catenin in development of bile ducts
inferred← citeshttps://doi.org/10.1016/j.gie.2024.02.021openalex-snapshot
Establishment of a patient-specific avatar organoid model derived from EUS-guided fine-needle biopsy for timely clinical application in pancreatic ductal adenocarcinoma (with video)
inferred← citeshttps://doi.org/10.1016/j.heares.2019.107838openalex-snapshot
Atoh1 is required in supporting cells for regeneration of vestibular hair cells in adult mice
inferred← citeshttps://doi.org/10.1016/j.heares.2022.108642openalex-snapshot
Sox2 is required in supporting cells for normal levels of vestibular hair cell regeneration in adult mice
inferred← citeshttps://doi.org/10.1016/j.heares.2026.109788openalex-snapshot
SOX10 restricts the formation of ectopic sensory patches in the postnatal mouse cochlea
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2014.12.004openalex-snapshot
Growth Factor Independence-1 (Gfi1) Is Required for Pancreatic Acinar Unit Formation and Centroacinar Cell Differentiation
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2015.06.007openalex-snapshot
Spontaneous Pancreatitis Caused by Tissue-Specific Gene Ablation of Hhex in Mice
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2019.02.004openalex-snapshot
Regulation of the Pancreatic Exocrine Differentiation Program and Morphogenesis by Onecut 1/Hnf6
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2019.06.005openalex-snapshot
Pancreatic Ductal Deletion of Hnf1b Disrupts Exocrine Homeostasis, Leads to Pancreatitis, and Facilitates Tumorigenesis
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2019.07.001openalex-snapshot
Differential Cell Susceptibilities to Kras in the Setting of Obstructive Chronic Pancreatitis
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2021.07.014openalex-snapshot
Uncertain Beginnings: Acinar and Ductal Cell Plasticity in the Development of Pancreatic Cancer
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2026.101743openalex-snapshot
The Stathmin 1-lineage Contributes to Acinar Regeneration but Not to Neoplasia Upon Oncogenic Kras Expression
inferred← citeshttps://doi.org/10.1016/j.jhep.2024.02.030openalex-snapshot
Van Gogh-like 2 is essential for the architectural patterning of the mammalian biliary tree
inferred← citeshttps://doi.org/10.1016/j.jhepr.2021.100416openalex-snapshot
Cellular origins of regenerating liver and hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1016/j.job.2021.01.005openalex-snapshot
Sox9 function in salivary gland development
inferred← citeshttps://doi.org/10.1016/j.mce.2016.11.008openalex-snapshot
Pancreatic β-cell regeneration: Facultative or dedicated progenitors?
inferred← citeshttps://doi.org/10.1016/j.mce.2021.111459openalex-snapshot
Stem/progenitor cells in normal physiology and disease of the pancreas
inferred← citeshttps://doi.org/10.1016/j.mmm.2021.10.004openalex-snapshot
La conversion de cellules α pancréatiques en cellules β : un mécanisme pour restaurer la masse des cellules β dans le diabète de type 1 ?
inferred← citeshttps://doi.org/10.1016/j.mod.2013.08.002openalex-snapshot
Stage specific reprogramming of mouse embryo liver cells to a beta cell-like phenotype
inferred← citeshttps://doi.org/10.1016/j.mod.2017.07.001openalex-snapshot
Cell adhesion molecules expression pattern indicates that somatic cells arbitrate gonadal sex of differentiating bipotential fetal mouse gonad
inferred← citeshttps://doi.org/10.1016/j.mod.2017.11.001openalex-snapshot
Transcriptional profiling validates involvement of extracellular matrix and proteinases genes in mouse gonad development
inferred← citeshttps://doi.org/10.1016/j.molmed.2020.04.003openalex-snapshot
Adult Pancreatic Acinar Progenitor-like Populations in Regeneration and Cancer
inferred← citeshttps://doi.org/10.1016/j.molmet.2022.101467openalex-snapshot
Physically interacting beta-delta pairs in the regenerating pancreas revealed by single-cell sequencing
inferred← citeshttps://doi.org/10.1016/j.regen.2021.100043openalex-snapshot
Improvements in stem cell to beta-cell differentiation for the treatment of diabetes
inferred← citeshttps://doi.org/10.1016/j.retram.2023.103412openalex-snapshot
Biochemical pancreatic β-cell lineage reprogramming: Various cell fate shifts
inferred← citeshttps://doi.org/10.1016/j.scr.2015.11.015openalex-snapshot
Cells with surface expression of CD133highCD71low are enriched for tripotent colony-forming progenitor cells in the adult murine pancreas
inferred← citeshttps://doi.org/10.1016/j.semcdb.2012.06.005openalex-snapshot
Lineage determinants in early endocrine development
inferred← citeshttps://doi.org/10.1016/j.semcdb.2012.06.008openalex-snapshot
Exocrine ontogenies: On the development of pancreatic acinar, ductal and centroacinar cells
inferred← citeshttps://doi.org/10.1016/j.semcdb.2015.08.013openalex-snapshot
Pax4 acts as a key player in pancreas development and plasticity
inferred← citeshttps://doi.org/10.1016/j.semcdb.2016.08.015openalex-snapshot
Molecular mechanisms of Sox transcription factors during the development of liver, bile duct, and pancreas
inferred← citeshttps://doi.org/10.1016/j.semcdb.2017.01.005openalex-snapshot
The molecular and morphogenetic basis of pancreas organogenesis
inferred← citeshttps://doi.org/10.1016/j.semcdb.2018.08.008openalex-snapshot
Mesodermal induction of pancreatic fate commitment
inferred← citeshttps://doi.org/10.1016/j.stem.2012.04.006openalex-snapshot
Tissue Stem Cells: New Tools and Functional Diversity
inferred← citeshttps://doi.org/10.1016/j.stem.2012.12.007openalex-snapshot
The Sox Family of Transcription Factors: Versatile Regulators of Stem and Progenitor Cell Fate
inferred← citeshttps://doi.org/10.1016/j.stem.2014.11.001openalex-snapshot
Plasticity and Dedifferentiation within the Pancreas: Development, Homeostasis, and Disease
inferred← citeshttps://doi.org/10.1016/j.stem.2016.03.016openalex-snapshot
Dclk1 Defines Quiescent Pancreatic Progenitors that Promote Injury-Induced Regeneration and Tumorigenesis
inferred← citeshttps://doi.org/10.1016/j.stem.2016.05.010openalex-snapshot
De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data
inferred← citeshttps://doi.org/10.1016/j.stem.2017.11.020openalex-snapshot
Endogenous Reprogramming of Alpha Cells into Beta Cells, Induced by Viral Gene Therapy, Reverses Autoimmune Diabetes
inferred← citeshttps://doi.org/10.1016/j.stem.2021.07.004openalex-snapshot
Continuous clonal labeling reveals uniform progenitor potential in the adult exocrine pancreas
inferred← citeshttps://doi.org/10.1016/j.stem.2021.10.005openalex-snapshot
New evidence for adult beta cell neogenesis
inferred← citeshttps://doi.org/10.1016/j.stem.2023.03.003openalex-snapshot
Matters arising: Insufficient evidence that pancreatic β cells are derived from adult ductal Neurog3-expressing progenitors
inferred← citeshttps://doi.org/10.1016/j.stem.2023.07.002openalex-snapshot
Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis
inferred← citeshttps://doi.org/10.1016/j.stemcr.2015.02.017openalex-snapshot
Efficient Generation of NKX6-1+ Pancreatic Progenitors from Multiple Human Pluripotent Stem Cell Lines
inferred← citeshttps://doi.org/10.1016/j.stemcr.2017.11.012openalex-snapshot
In Vitro Induction and In Vivo Engraftment of Lung Bud Tip Progenitor Cells Derived from Human Pluripotent Stem Cells
inferred← citeshttps://doi.org/10.1016/j.stemcr.2018.01.028openalex-snapshot
Heterogeneity of SOX9 and HNF1β in Pancreatic Ducts Is Dynamic
inferred← citeshttps://doi.org/10.1016/j.stemcr.2018.02.005openalex-snapshot
Expansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation Potential
inferred← citeshttps://doi.org/10.1016/j.stemcr.2023.02.001openalex-snapshot
Methylcellulose colony assay and single-cell micro-manipulation reveal progenitor-like cells in adult human pancreatic ducts
inferred← citeshttps://doi.org/10.1016/j.tcb.2021.09.007openalex-snapshot
Harnessing orthogonal recombinases to decipher cell fate with enhanced precision
inferred← citeshttps://doi.org/10.1016/j.tem.2015.12.005openalex-snapshot
Chromatin Regulators in Pancreas Development and Diabetes
inferred← citeshttps://doi.org/10.1016/j.tem.2016.01.002openalex-snapshot
Lineage Reprogramming: A Promising Road for Pancreatic β Cell Regeneration
inferred← citeshttps://doi.org/10.1016/j.tem.2018.10.002openalex-snapshot
Pancreatic Progenitors: There and Back Again
inferred← citeshttps://doi.org/10.1016/j.tem.2024.12.008openalex-snapshot
Lineage tracing of pancreatic cells for mechanistic and therapeutic insights
inferred← citeshttps://doi.org/10.1016/j.trecan.2016.11.005openalex-snapshot
Differentiation and Inflammation: ‘Best Enemies’ in Gastrointestinal Carcinogenesis
inferred← citeshttps://doi.org/10.1016/j.ydbio.2011.10.025openalex-snapshot
Competence of failed endocrine progenitors to give rise to acinar but not ductal cells is restricted to early pancreas development
inferred← citeshttps://doi.org/10.1016/j.ydbio.2012.04.002openalex-snapshot
Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration
inferred← citeshttps://doi.org/10.1016/j.ydbio.2012.10.030openalex-snapshot
ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools
inferred← citeshttps://doi.org/10.1016/j.ydbio.2013.04.003openalex-snapshot
Smad signaling pathways regulate pancreatic endocrine development
inferred← citeshttps://doi.org/10.1016/j.ydbio.2014.03.019openalex-snapshot
Distinct requirements for beta-catenin in pancreatic epithelial growth and patterning
inferred← citeshttps://doi.org/10.1016/j.ydbio.2015.07.002openalex-snapshot
REST represses a subset of the pancreatic endocrine differentiation program
inferred← citeshttps://doi.org/10.1016/j.ydbio.2016.02.027openalex-snapshot
Centroacinar cells: At the center of pancreas regeneration
inferred← citeshttps://doi.org/10.1016/j.ydbio.2021.03.001openalex-snapshot
Evolution of organoid technology: Lessons learnt in Co-Culture systems from developmental biology
inferred← citeshttps://doi.org/10.1016/j.yexcr.2014.01.030openalex-snapshot
Thyroid hormones promote endocrine differentiation at expenses of exocrine tissue
inferred← citeshttps://doi.org/10.1016/j.ymthe.2018.02.014openalex-snapshot
Long-Term Correction of Diabetes in Mice by In Vivo Reprogramming of Pancreatic Ducts
inferred← citeshttps://doi.org/10.1021/acsptsci.9b00048openalex-snapshot
Inventing Liraglutide, a Glucagon-Like Peptide-1 Analogue, for the Treatment of Diabetes and Obesity
inferred← citeshttps://doi.org/10.1038/cddis.2013.52openalex-snapshot
Neurogenin 3+ cells contribute to β-cell neogenesis and proliferation in injured adult mouse pancreas
inferred← citeshttps://doi.org/10.1038/emboj.2013.204openalex-snapshot
Unlimited in vitro expansion of adult bi‐potent pancreas progenitors through the Lgr5/R‐spondin axis
inferred← citeshttps://doi.org/10.1038/labinvest.2013.113openalex-snapshot
Specific transduction and labeling of pancreatic ducts by targeted recombinant viral infusion into mouse pancreatic ducts
inferred← citeshttps://doi.org/10.1038/nature20132openalex-snapshot
LKB1 loss links serine metabolism to DNA methylation and tumorigenesis
inferred← citeshttps://doi.org/10.1038/nbt.2747openalex-snapshot
Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice
inferred← citeshttps://doi.org/10.1038/ncb3309openalex-snapshot
Stem cells versus plasticity in liver and pancreas regeneration
inferred← citeshttps://doi.org/10.1038/ncomms14127openalex-snapshot
Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2
inferred← citeshttps://doi.org/10.1038/nrendo.2013.145openalex-snapshot
The use of stem cells for pancreatic regeneration in diabetes mellitus
inferred← citeshttps://doi.org/10.1038/nrgastro.2011.114openalex-snapshot
From tissue turnover to the cell of origin for pancreatic cancer
inferred← citeshttps://doi.org/10.1038/nrgastro.2017.12openalex-snapshot
Acinar cell plasticity and development of pancreatic ductal adenocarcinoma
inferred← citeshttps://doi.org/10.1038/nrgastro.2017.93openalex-snapshot
Regenerative medicine and cell-based approaches to restore pancreatic function
inferred← citeshttps://doi.org/10.1038/s12276-021-00593-zopenalex-snapshot
Insulin-positive ductal cells do not migrate into preexisting islets during pregnancy
inferred← citeshttps://doi.org/10.1038/s41388-021-01701-zopenalex-snapshot
Statins repress hedgehog signaling in medulloblastoma with no bone toxicities
inferred← citeshttps://doi.org/10.1038/s41388-021-01771-zopenalex-snapshot
Loss of activating transcription factor 3 prevents KRAS-mediated pancreatic cancer
inferred← citeshttps://doi.org/10.1038/s41388-026-03960-0openalex-snapshot
PTEN-AKT2 regulates mixed lineage liver cancer development and sensitizes cancer cells to TGFβ treatment
inferred← citeshttps://doi.org/10.1038/s41392-023-01707-xopenalex-snapshot
EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors
inferred← citeshttps://doi.org/10.1038/s41419-024-06738-yopenalex-snapshot
Reg4 deficiency aggravates pancreatitis by increasing mitochondrial cell death and fibrosis
inferred← citeshttps://doi.org/10.1038/s41420-017-0014-5openalex-snapshot
Single-cell analyses of human islet cells reveal de-differentiation signatures
inferred← citeshttps://doi.org/10.1038/s41421-022-00485-0openalex-snapshot
Use of a dual genetic system to decipher exocrine cell fate conversions in the adult pancreas
inferred← citeshttps://doi.org/10.1038/s41467-017-00258-4openalex-snapshot
Stochastic priming and spatial cues orchestrate heterogeneous clonal contribution to mouse pancreas organogenesis
inferred← citeshttps://doi.org/10.1038/s41467-017-00666-6openalex-snapshot
Endoderm Jagged induces liver and pancreas duct lineage in zebrafish
inferred← citeshttps://doi.org/10.1038/s41467-018-05740-1openalex-snapshot
Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis
inferred← citeshttps://doi.org/10.1038/s41467-021-23673-0openalex-snapshot
Reinforcing one-carbon metabolism via folic acid/Folr1 promotes β-cell differentiation
inferred← citeshttps://doi.org/10.1038/s41467-026-77522-zopenalex-snapshot
Epithelial-mesenchymal Wnt crosstalk directs planar cell polarity in the developing cochlea
inferred← citeshttps://doi.org/10.1038/s41551-021-00757-2openalex-snapshot
Single-cell-resolved differentiation of human induced pluripotent stem cells into pancreatic duct-like organoids on a microwell chip
inferred← citeshttps://doi.org/10.1038/s41575-025-01116-1openalex-snapshot
Advances in liver and pancreas organoids: how far we have come and where we go next
inferred← citeshttps://doi.org/10.1038/s41586-018-0762-2openalex-snapshot
Mechanosignalling via integrins directs fate decisions of pancreatic progenitors
inferred← citeshttps://doi.org/10.1038/s41589-022-01047-xopenalex-snapshot
MNK2 deficiency potentiates β-cell regeneration via translational regulation
inferred← citeshttps://doi.org/10.1038/s41589-024-01822-yopenalex-snapshot
Mechanistic insights and approaches for beta cell regeneration
inferred← citeshttps://doi.org/10.1038/s41598-017-08197-2openalex-snapshot
Lacrimal Gland Repair after Short-term Obstruction of Excretory Duct in Rabbits
inferred← citeshttps://doi.org/10.1038/s41598-017-12721-9openalex-snapshot
Acinar cells in the neonatal pancreas grow by self-duplication and not by neogenesis from duct cells
inferred← citeshttps://doi.org/10.1038/s41598-017-17884-zopenalex-snapshot
Identification of Newly Committed Pancreatic Cells in the Adult Mouse Pancreas
inferred← citeshttps://doi.org/10.1038/s41598-018-26404-6openalex-snapshot
Porcine Neonatal Pancreatic Cell Clusters Maintain Their Multipotency in Culture and After Transplantation
inferred← citeshttps://doi.org/10.1038/s41598-019-51763-zopenalex-snapshot
Highly efficient ex vivo lentiviral transduction of primary human pancreatic exocrine cells
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