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Development of a Zn 2+-Chelating But Highly Selective Matrix Metalloproteinase 13 Inhibitor

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inferredcites →https://doi.org/10.1002/art.10531openalex-extracted
Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro
inferredcites →https://doi.org/10.1002/cmdc.201700349openalex-extracted
Recent Research Advances in Selective Matrix Metalloproteinase‐13 Inhibitors as Anti‐Osteoarthritis Agents
inferredcites →https://doi.org/10.1016/j.bmc.2008.03.004openalex-extracted
High throughput screening of potentially selective MMP-13 exosite inhibitors utilizing a triple-helical FRET substrate
inferredcites →https://doi.org/10.1016/j.bmc.2014.07.025openalex-extracted
Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: Highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1″ binding site
inferredcites →https://doi.org/10.1016/j.tox.2009.01.006openalex-extracted
Assessment of the renal toxicity of novel anti-inflammatory compounds using cynomolgus monkey and human kidney cells
inferredcites →https://doi.org/10.1021/acs.jmedchem.6b01007openalex-extracted
Discovery of Novel, Highly Potent, and Selective Matrix Metalloproteinase (MMP)-13 Inhibitors with a 1,2,4-Triazol-3-yl Moiety as a Zinc Binding Group Using a Structure-Based Design Approach
inferredcites →https://doi.org/10.1021/acs.jmedchem.7b00514openalex-extracted
Structure-Based Design and Synthesis of Potent and Selective Matrix Metalloproteinase 13 Inhibitors
inferredcites →https://doi.org/10.1021/jm501284eopenalex-extracted
Characterization of Selective Exosite-Binding Inhibitors of Matrix Metalloproteinase 13 That Prevent Articular Cartilage Degradation in Vitro
inferredcites →https://doi.org/10.1021/jm9018788openalex-extracted
Oxetanes in Drug Discovery: Structural and Synthetic Insights
inferredcites →https://doi.org/10.1038/nri1418openalex-extracted
Matrix metalloproteinases as modulators of inflammation and innate immunity
inferredcites →https://doi.org/10.1038/sj.bjc.6600858openalex-extracted
Role of RANKL-induced osteoclast formation and MMP-dependent matrix degradation in bone destruction by breast cancer metastasis
inferredcites →https://doi.org/10.1039/c2md20111aopenalex-extracted
The developability of heteroaromatic and heteroaliphatic rings – do some have a better pedigree as potential drug molecules than others?
inferredcites →https://doi.org/10.1039/d0md00370kopenalex-extracted
Put a ring on it: application of small aliphatic rings in medicinal chemistry
inferredcites →https://doi.org/10.1074/jbc.m313474200openalex-extracted
Similarity of Binding Sites of Human Matrix Metalloproteinases
inferredcites →https://doi.org/10.1172/jci10564openalex-extracted
Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice
inferredcites →https://doi.org/10.2165/11318390-000000000-00000openalex-extracted
Matrix Metalloproteinase Inhibitors
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