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Angptl4 May Serve as a Marker of Cognitive Impairment in Patients with Cerebral Small Vessel Disease

https://doi.org/10.2139/ssrn.4606226
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Risk Factors Associated With Incident Cerebral Microbleeds According to Location in Older People
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Angiopoietin‐like protein 4 and clinical outcomes in ischemic stroke patients
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Cognitive impairment in sporadic cerebral small vessel disease: A systematic review and meta‐analysis
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Blood–brain barrier leakage at baseline and cognitive decline in cerebral small vessel disease: a 2-year follow-up study
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Endothelial Nitric Oxide Synthase–Deficient Mice
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Inflammation and cerebral small vessel disease: A systematic review
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Triglyceride sensing in the reward circuitry: A new insight in feeding behaviour regulation
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ANGPTL4 attenuates palmitic acid-induced endothelial cell injury by increasing autophagy
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Glucose tolerance and insulin sensitivity are impaired in APP/PS1 transgenic mice prior to amyloid plaque pathogenesis and cognitive decline
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Role and mechanism of the action of angiopoietin-like protein ANGPTL4 in plasma lipid metabolism
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Hypertriglyceridemia as a possible predictor of early neurological deterioration in acute lacunar stroke
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Inhibition of STAT3 phosphorylation attenuates impairments in learning and memory in 5XFAD mice, an animal model of Alzheimer's disease
inferredcites →https://doi.org/10.1016/j.molmed.2019.05.010openalex-extracted
ANGPTL4 in Metabolic and Cardiovascular Disease
inferredcites →https://doi.org/10.1016/j.molmet.2014.11.003openalex-extracted
Differential effects of angiopoietin-like 4 in brain and muscle on regulation of lipoprotein lipase activity
inferredcites →https://doi.org/10.1016/j.neuroscience.2020.08.037openalex-extracted
Structural Brain Network Disruption at Preclinical Stage of Cognitive Impairment Due to Cerebral Small Vessel Disease
inferredcites →https://doi.org/10.1016/j.nicl.2015.02.003openalex-extracted
White matter integrity in small vessel disease is related to cognition
inferredcites →https://doi.org/10.1016/j.vph.2022.106997openalex-extracted
Targeting endothelial ion signalling to rescue cerebral blood flow in cerebral disorders
inferredcites →https://doi.org/10.1016/s0140-6736(20)30367-6openalex-extracted
Dementia prevention, intervention, and care: 2020 report of the Lancet Commission
inferredcites →https://doi.org/10.1016/s1474-4422(19)30079-1openalex-extracted
Small vessel disease: mechanisms and clinical implications
inferredcites →https://doi.org/10.1038/hr.2015.4openalex-extracted
Endothelial dysfunction is associated with the severity of cerebral small vessel disease
inferredcites →https://doi.org/10.1038/jcbfm.2015.12openalex-extracted
Gliovascular Disruption and Cognitive Deficits in a Mouse Model with Features of Small Vessel Disease
inferredcites →https://doi.org/10.1038/s12276-023-00937-xopenalex-extracted
ANGPTL4 stabilizes atherosclerotic plaques and modulates the phenotypic transition of vascular smooth muscle cells through KLF4 downregulation
inferredcites →https://doi.org/10.1038/s41598-018-26475-5openalex-extracted
OCT-Angiography reveals reduced vessel density in the deep retinal plexus of CADASIL patients
inferredcites →https://doi.org/10.1038/sj.jcbfm.9600408openalex-extracted
Vascular Response to Hypoxic Preconditioning in the Immature Brain
inferredcites →https://doi.org/10.1042/bsr20110102openalex-extracted
Angiopoietin-like 4: a decade of research
inferredcites →https://doi.org/10.1073/pnas.1423765112openalex-extracted
Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy
inferredcites →https://doi.org/10.1074/jbc.m110.172106openalex-extracted
Lipoprotein Lipase Is a Novel Amyloid β (Aβ)-binding Protein That Promotes Glycosaminoglycan-dependent Cellular Uptake of Aβ in Astrocytes
inferredcites →https://doi.org/10.1074/jbc.m111.220061openalex-extracted
Alteration of Developmental and Pathological Retinal Angiogenesis in angptl4-deficient Mice
inferredcites →https://doi.org/10.1080/13607863.2012.688190openalex-extracted
Cognitive function with glucose tolerance status and obesity in Chinese middle-aged and aged adults
inferredcites →https://doi.org/10.1093/brain/awy274openalex-extracted
Angiopoietin like-4 as a novel vascular mediator in capillary cerebral amyloid angiopathy
inferredcites →https://doi.org/10.1093/eurheartj/eht153openalex-extracted
Protective effects of angiopoietin-like 4 on cerebrovascular and functional damages in ischaemic stroke
inferredcites →https://doi.org/10.1097/wco.0000000000000913openalex-extracted
Cerebral small vessel disease and vascular cognitive impairment: from diagnosis to management
inferredcites →https://doi.org/10.1111/ene.15108openalex-extracted
Synergistic associations of cognitive and motor impairments with functional outcome in covert cerebral small vessel disease
inferredcites →https://doi.org/10.1111/joim.13339openalex-extracted
Angiopoietin‐2 and angiopoietin‐like 4 protein provide prognostic information in patients with suspected acute coronary syndrome
inferredcites →https://doi.org/10.1113/jp271752openalex-extracted
Angiopoietin‐like 4 promotes angiogenesis in the tendon and is increased in cyclically loaded tendon fibroblasts
inferredcites →https://doi.org/10.1126/scitranslmed.aam9507openalex-extracted
Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats
inferredcites →https://doi.org/10.1128/mbio.02469-18openalex-extracted
Antibody Treatment against Angiopoietin-Like 4 Reduces Pulmonary Edema and Injury in Secondary Pneumococcal Pneumonia
inferredcites →https://doi.org/10.1136/bmjdrc-2022-002897openalex-extracted
Insulin resistance based on postglucose load measure is associated with prevalence and burden of cerebral small vessel disease
inferredcites →https://doi.org/10.1155/2018/1361780openalex-extracted
Hypertriglyceridemia Is Associated with Reduced Leukoaraiosis Severity in Patients with a Small Vessel Stroke
inferredcites →https://doi.org/10.1155/2020/8894868openalex-extracted
Large-Scale Internetwork Functional Connectivity Mediates the Relationship between Serum Triglyceride and Working Memory in Young Adulthood
inferredcites →https://doi.org/10.1159/000478529openalex-extracted
Cerebral Small Vessel Disease Is Associated with Dysregulation in the Ubiquitin Proteasome System and Other Major Cellular Pathways in Specific Brain Regions
inferredcites →https://doi.org/10.1159/000510053openalex-extracted
Biomarkers Related to Endothelial Dysfunction and Vascular Cognitive Impairment: A Systematic Review
inferredcites →https://doi.org/10.1161/atvbaha.107.157776openalex-extracted
Suppression of the Raf/MEK/ERK Signaling Cascade and Inhibition of Angiogenesis by the Carboxyl Terminus of Angiopoietin-Like Protein 4
inferredcites →https://doi.org/10.1161/hypertensionaha.119.13023openalex-extracted
Microvascular Dysfunction Is Associated With Worse Cognitive Performance
inferredcites →https://doi.org/10.1161/strokeaha.118.023788openalex-extracted
Blood-Brain Barrier Leakage and Microvascular Lesions in Cerebral Amyloid Angiopathy
inferredcites →https://doi.org/10.1161/strokeaha.121.035674openalex-extracted
Oxygen Metabolic Stress and White Matter Injury in Patients With Cerebral Small Vessel Disease
inferredcites →https://doi.org/10.1172/jci.insight.125437openalex-extracted
Antiinflammatory activity of ANGPTL4 facilitates macrophage polarization to induce cardiac repair
inferredcites →https://doi.org/10.1172/jci.insight.97918openalex-extracted
Absence of ANGPTL4 in adipose tissue improves glucose tolerance and attenuates atherogenesis
inferredcites →https://doi.org/10.1172/jci39733openalex-extracted
Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease
inferredcites →https://doi.org/10.1177/0271678x221076557openalex-extracted
Assessment of microvascular rarefaction in human brain disorders using physiological magnetic resonance imaging
inferredcites →https://doi.org/10.1177/0271678x221135658openalex-extracted
Retinal capillary microvessel morphology changes are associated with vascular damage and dysfunction in cerebral small vessel disease
inferredcites →https://doi.org/10.1177/17474930211012837openalex-extracted
Cognitive impact of cerebral microbleeds in patients with symptomatic small vessel disease
inferredcites →https://doi.org/10.1182/blood-2011-01-328716openalex-extracted
ANGPTL4 modulates vascular junction integrity by integrin signaling and disruption of intercellular VE-cadherin and claudin-5 clusters
inferredcites →https://doi.org/10.1186/s12885-020-07343-wopenalex-extracted
ANGPTL4 overexpression inhibits tumor cell adhesion and migration and predicts favorable prognosis of triple-negative breast cancer
inferredcites →https://doi.org/10.1186/s12944-016-0401-6openalex-extracted
Effects of the duration of hyperlipidemia on cerebral lipids, vessels and neurons in rats
inferredcites →https://doi.org/10.1186/s12974-021-02071-9openalex-extracted
Activated STAT3 signaling pathway by ligature-induced periodontitis could contribute to neuroinflammation and cognitive impairment in rats
inferredcites →https://doi.org/10.1186/s40035-020-00221-2openalex-extracted
Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes
inferredcites →https://doi.org/10.1194/jlr.m034272openalex-extracted
Effect of chronic intermittent hypoxia on triglyceride uptake in different tissues
inferredcites →https://doi.org/10.1212/wnl.0000000000007654openalex-extracted
CNS small vessel disease
inferredcites →https://doi.org/10.12659/msm.915748openalex-extracted
Angiopoietin-Like Protein 4 (ANGPTL4) Induces Retinal Pigment Epithelial Barrier Breakdown by Activating Signal Transducer and Activator of Transcription 3 (STAT3): Evidence from ARPE-19 Cells Under Hypoxic Condition and Diabetic Rats
inferredcites →https://doi.org/10.18632/aging.103154openalex-extracted
White matter hyperintensities associated with progression of cerebral small vessel disease: a 7-year Chinese urban community study
inferredcites →https://doi.org/10.21203/rs.3.rs-116001/v1openalex-extracted
inferredcites →https://doi.org/10.21203/rs.3.rs-34444/v3openalex-extracted
inferredcites →https://doi.org/10.2147/ndt.s354022openalex-extracted
Diagnostic Values of Serum Levels of Homocysteine, Heat Shock Protein 70 and High-Sensitivity C-Reactive Protein for Predicting Vascular Cognitive Impairment
inferredcites →https://doi.org/10.2147/ndt.s401098openalex-extracted
Systemic Immune-Inflammation Index is Associated with Cerebral Small Vessel Disease Burden and Cognitive Impairment
inferredcites →https://doi.org/10.2174/1567202612666151027151025openalex-extracted
Identification of Inflammatory, Metabolic, and Cell Survival Pathways Contributing to Cerebral Small Vessel Disease by Postmortem Gene Expression Microarray
inferredcites →https://doi.org/10.2174/1567202616666191023111059openalex-extracted
Combined Transcriptomic and Proteomic Analyses of Cerebral Frontal Lobe Tissue Identified RNA Metabolism Dysregulation as One Potential Pathogenic Mechanism in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL)
inferredcites →https://doi.org/10.2174/1567205018666210922105850openalex-extracted
Decreased Plasma Level of Lipoprotein Lipase Predicted Verbal Disfluency in Chinese Type 2 Diabetes Mellitus Patients with Early Cognitive Deficits
inferredcites →https://doi.org/10.3174/ajnr.a7630openalex-extracted
Arterial Spin-Labeling Parameters and Their Associations with Risk Factors, Cerebral Small-Vessel Disease, and Etiologic Subtypes of Cognitive Impairment and Dementia
inferredcites →https://doi.org/10.3233/jad-170205openalex-extracted
Changes in Expression Profiles Revealed by Transcriptomic Analysis in Peripheral Blood Mononuclear Cells of Alzheimer’s Disease Patients
inferredcites →https://doi.org/10.3389/fimmu.2022.841290openalex-extracted
Adenosine A2A Receptor Suppressed Astrocyte-Mediated Inflammation Through the Inhibition of STAT3/YKL-40 Axis in Mice With Chronic Cerebral Hypoperfusion-induced White Matter Lesions
inferredcites →https://doi.org/10.3389/fnagi.2021.609679openalex-extracted
The Therapeutic Targets of Fingolimod (FTY720) Are Involved in Pathological Processes in the Frontal Cortex of Alzheimer's Disease Patients: A Network Pharmacology Study
inferredcites →https://doi.org/10.3389/fncel.2018.00380openalex-extracted
Cerebrovascular Pathology in Hypertriglyceridemic APOB-100 Transgenic Mice
inferredcites →https://doi.org/10.3389/fneur.2022.861714openalex-extracted
Advances in the Role of Endothelial Cells in Cerebral Small Vessel Disease
inferredcites →https://doi.org/10.3389/fnmol.2022.1044022openalex-extracted
Transcriptome-wide association study reveals cholesterol metabolism gene Lpl is a key regulator of cognitive dysfunction
inferredcites →https://doi.org/10.3389/fphar.2022.850967openalex-extracted
ANGPTL4 Regulates Psoriasis via Modulating Hyperproliferation and Inflammation of Keratinocytes
inferredcites →https://doi.org/10.3390/ijms20194906openalex-extracted
Methylglyoxal and Glyoxal as Potential Peripheral Markers for MCI Diagnosis and Their Effects on the Expression of Neurotrophic, Inflammatory and Neurodegenerative Factors in Neurons and in Neuronal Derived-Extracellular Vesicles
inferredcites →https://doi.org/10.3390/ijms23116224openalex-extracted
Neuroinflammation in Vascular Cognitive Impairment and Dementia: Current Evidence, Advances, and Prospects
inferredcites →https://doi.org/10.3390/nu13062118openalex-extracted
The Role of High Triglycerides Level in Predicting Cognitive Impairment: A Review of Current Evidence
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