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https://doi.org/10.2139/ssrn.4635544

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In vivo dual-targeted chemotherapy of drug resistant cancer by rationally designed nanocarrier
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Structure based discovery of novel hexokinase 2 inhibitors
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Discovery of a novel phenylethyl benzamide glucokinase activator for the treatment of type 2 diabetes mellitus
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An update on therapeutic opportunities offered by cancer glycolytic metabolism
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Evaluation of biological properties of 3,3′,4,4′-benzophenonetetracarboxylic dianhydride derivatives and their ability to inhibit hexokinase activity
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Co-targeting of BET proteins and HDACs as a novel approach to trigger apoptosis in rhabdomyosarcoma cells
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A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance
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Resistance Is Futile: Targeting Mitochondrial Energetics and Metabolism to Overcome Drug Resistance in Cancer Treatment
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A review on machine learning approaches and trends in drug discovery
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Co-targeting hexokinase 2-mediated Warburg effect and ULK1-dependent autophagy suppresses tumor growth of PTEN- and TP53- deficiency-driven castration-resistant prostate cancer
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Synthesis of novel andrographolide beckmann rearrangement derivatives and evaluation of their HK2-related anti-inflammatory activities
inferredcites →https://doi.org/10.1016/j.ejor.2019.04.013openalex-extracted
Large data sets and machine learning: Applications to statistical arbitrage
inferredcites →https://doi.org/10.1016/j.phrs.2020.105367openalex-extracted
Novel selective hexokinase 2 inhibitor Benitrobenrazide blocks cancer cells growth by targeting glycolysis
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Hexokinase-2 bound to mitochondria: Cancer's stygian link to the “Warburg effect” and a pivotal target for effective therapy
inferredcites →https://doi.org/10.1016/s0005-2728(02)00248-7openalex-extracted
Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention
inferredcites →https://doi.org/10.1021/acs.jcim.1c00683openalex-extracted
Machine Learning Models Identify Inhibitors of SARS-CoV-2
inferredcites →https://doi.org/10.1021/acs.jnatprod.8b00821openalex-extracted
Strepantibins A–C: Hexokinase II Inhibitors from a Mud Dauber Wasp Associated Streptomyces sp.
inferredcites →https://doi.org/10.1021/jm2014887openalex-extracted
Discovery of (S)-6-(3-Cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic Acid as a Hepatoselective Glucokinase Activator Clinical Candidate for Treating Type 2 Diabetes Mellitus
inferredcites →https://doi.org/10.1021/ml5004712openalex-extracted
Design and Synthesis of Acetylenyl Benzamide Derivatives as Novel Glucokinase Activators for the Treatment of T2DM
inferredcites →https://doi.org/10.1021/mp300547hopenalex-extracted
Identification of Novel Breast Cancer Resistance Protein (BCRP) Inhibitors by Virtual Screening
inferredcites →https://doi.org/10.1023/a:1022494613613openalex-extracted
Aberrant Glycolytic Metabolism of Cancer Cells: A Remarkable Coordination of Genetic, Transcriptional, Post-translational, and Mutational Events That Lead to a Critical Role for Type II Hexokinase
inferredcites →https://doi.org/10.1038/s41467-017-02733-4openalex-extracted
Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin
inferredcites →https://doi.org/10.1038/s42003-021-01899-4openalex-extracted
Architectural control of metabolic plasticity in epithelial cancer cells
inferredcites →https://doi.org/10.1080/07391102.2021.1942217openalex-extracted
Identification of plant-based hexokinase 2 inhibitors: combined molecular docking and dynamics simulation studies
inferredcites →https://doi.org/10.1080/17460441.2018.1465407openalex-extracted
Advancing drug discovery via GPU-based deep learning
inferredcites →https://doi.org/10.1093/nar/gkr777openalex-extracted
ChEMBL: a large-scale bioactivity database for drug discovery
inferredcites →https://doi.org/10.1126/science.1160809openalex-extracted
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
inferredcites →https://doi.org/10.1145/2818302openalex-extracted
Proceedings of the 8th Workshop on Programming Languages and Operating Systems
inferredcites →https://doi.org/10.1146/annurev-cellbio-092910-154237openalex-extracted
Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
inferredcites →https://doi.org/10.1186/s12859-022-05017-xopenalex-extracted
Prediction of HIV-1 protease cleavage site from octapeptide sequence information using selected classifiers and hybrid descriptors
inferredcites →https://doi.org/10.1200/jco.2008.21.4437openalex-extracted
Randomized Study of Lapatinib Alone or in Combination With Trastuzumab in Women With ErbB2-Positive, Trastuzumab-Refractory Metastatic Breast Cancer
inferredcites →https://doi.org/10.1371/journal.pbio.3000819openalex-extracted
Rational design of balanced dual-targeting antibiotics with limited resistance
inferredcites →https://doi.org/10.1371/journal.pone.0121046openalex-extracted
Tumor Cells Switch to Mitochondrial Oxidative Phosphorylation under Radiation via mTOR-Mediated Hexokinase II Inhibition - A Warburg-Reversing Effect
inferredcites →https://doi.org/10.1787/9789264085442-enopenalex-extracted
Guidance Document on the Validation of (Quantitative) Structure-Activity Relationship [(Q)SAR] Models
inferredcites →https://doi.org/10.18637/jss.v036.i11openalex-extracted
Feature Selection with the Boruta Package
inferredcites →https://doi.org/10.2174/092986709787846578openalex-extracted
Mitochondrial Respiratory Complex I: Structure, Function and Implication in Human Diseases
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