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Impact of Per- and Polyfluoroalkyl Substances on Oxidative Stress and Metabolic Biomarkers in Human Neuronal Cells

https://doi.org/10.2139/ssrn.4760931
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Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research
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Oxidative stress, DNA damage, and antioxidant enzyme activity induced by hexavalent chromium in Sprague‐Dawley rats
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Metabolic Effects PFAS
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Effects of perfluorooctanoate and perfluorooctane sulfonate exposure on hepatoma Hep G2 cells
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Cytotoxicity of novel fluorinated alternatives to long-chain perfluoroalkyl substances to human liver cell line and their binding capacity to human liver fatty acid binding protein
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Role of Polypeptide Inflammatory Biomarkers in the Diagnosis and Monitoring of COVID-19
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Study on the binding interaction between perfluoroalkyl acids and DNA
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PFAS Exposures and the Human Metabolome: A Systematic Review of Epidemiological Studies
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A spectrophotometric method for determination of catalase activity in small tissue samples
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Anticancer Activities of African Medicinal Spices and Vegetables
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The antioxidant glutathione
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Induction of oxidative stress and apoptosis by PFOS and PFOA in primary cultured hepatocytes of freshwater tilapia (Oreochromis niloticus)
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A Mitochondria-K+ Channel Axis Is Suppressed in Cancer and Its Normalization Promotes Apoptosis and Inhibits Cancer Growth
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Perfluorooctanoic acid induces peroxisomal fatty acid oxidation and cytokine expression in the liver of male Japanese medaka (Oryzias latipes)
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Mechanistic toxicity study of perfluorooctanoic acid in zebrafish suggests mitochondrial dysfunction to play a key role in PFOA toxicity
inferredcites →https://doi.org/10.1016/j.chemosphere.2014.10.014openalex-extracted
Perfluoroalkylated substances (PFAS) affect oxidative stress biomarkers in vitro
inferredcites →https://doi.org/10.1016/j.copbio.2014.12.007openalex-extracted
A nexus for cellular homeostasis: the interplay between metabolic and signal transduction pathways
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A critical comparison of cellular and cell-free bioproduction systems
inferredcites →https://doi.org/10.1016/j.envint.2013.06.004openalex-extracted
Accumulation of perfluoroalkyl substances in human tissues
inferredcites →https://doi.org/10.1016/j.envint.2013.08.021openalex-extracted
Fluorinated alternatives to long-chain perfluoroalkyl carboxylic acids (PFCAs), perfluoroalkane sulfonic acids (PFSAs) and their potential precursors
inferredcites →https://doi.org/10.1016/j.envint.2019.105048openalex-extracted
Legacy and alternative per- and polyfluoroalkyl substances in the U.S. general population: Paired serum-urine data from the 2013–2014 National Health and Nutrition Examination Survey
inferredcites →https://doi.org/10.1016/j.envint.2019.105220openalex-extracted
Perfluoroalkyl substances and severity of nonalcoholic fatty liver in Children: An untargeted metabolomics approach
inferredcites →https://doi.org/10.1016/j.envint.2021.106621openalex-extracted
Environmental exposure to perfluoroalkyl substances in early pregnancy, maternal glucose homeostasis and the risk of gestational diabetes: A prospective cohort study
inferredcites →https://doi.org/10.1016/j.envint.2022.107149openalex-extracted
Human exposure pathways to poly- and perfluoroalkyl substances (PFAS) from indoor media: A systematic review
inferredcites →https://doi.org/10.1016/j.envint.2022.107455openalex-extracted
Food grown on fire stations as a potential pathway for firefighters’ exposure to per- and poly-fluoroalkyl substances (PFAS)
inferredcites →https://doi.org/10.1016/j.envint.2023.107851openalex-extracted
Metabolic perturbations in pregnant rats exposed to low-dose perfluorooctanesulfonic acid: An integrated multi-omics analysis
inferredcites →https://doi.org/10.1016/j.envint.2023.107951openalex-extracted
Insight into the binding model of per- and polyfluoroalkyl substances to proteins and membranes
inferredcites →https://doi.org/10.1016/j.envpol.2017.04.086openalex-extracted
Serum metabolome biomarkers associate low-level environmental perfluorinated compound exposure with oxidative /nitrosative stress in humans
inferredcites →https://doi.org/10.1016/j.envres.2019.05.008openalex-extracted
PFOA and PFOS interact with superoxide dismutase and induce cytotoxicity in mouse primary hepatocytes: A combined cellular and molecular methods
inferredcites →https://doi.org/10.1016/j.envres.2021.111724openalex-extracted
Do perfluoroalkyl substances aggravate the occurrence of obesity-associated glucolipid metabolic disease?
inferredcites →https://doi.org/10.1016/j.envres.2023.115424openalex-extracted
Short-chain per- and polyfluoralkyl substances (PFAS) effects on oxidative stress biomarkers in human liver, kidney, muscle, and microglia cell lines
inferredcites →https://doi.org/10.1016/j.fct.2023.114117openalex-extracted
Rapid enzymatic activity model (REAM) to decipher the toxic action of per- and polyfluoroalkyl substances
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2016.02.028openalex-extracted
The role of glutathione reductase and related enzymes on cellular redox homoeostasis network
inferredcites →https://doi.org/10.1016/j.jes.2019.08.016openalex-extracted
The short-chain perfluorinated compounds PFBS, PFHxS, PFBA and PFHxA, disrupt human mesenchymal stem cell self-renewal and adipogenic differentiation
inferredcites →https://doi.org/10.1016/j.jhazmat.2022.128615openalex-extracted
Systematic developmental toxicity assessment of a structurally diverse library of PFAS in zebrafish
inferredcites →https://doi.org/10.1016/j.mrgentox.2010.04.024openalex-extracted
Genotoxic potential of the perfluorinated chemicals PFOA, PFOS, PFBS, PFNA and PFHxA in human HepG2 cells
inferredcites →https://doi.org/10.1016/j.neuro.2021.05.009openalex-extracted
Metabolic profiling in human SH-SY5Y neuronal cells exposed to perfluorooctanoic acid (PFOA)
inferredcites →https://doi.org/10.1016/j.neuro.2022.07.008openalex-extracted
The SH-SY5Y human neuroblastoma cell line, a relevant in vitro cell model for investigating neurotoxicology in human: Focus on organic pollutants
inferredcites →https://doi.org/10.1016/j.ntt.2023.107174openalex-extracted
Sources, occurrence and toxic effects of emerging per- and polyfluoroalkyl substances (PFAS)
inferredcites →https://doi.org/10.1016/j.reprotox.2021.07.002openalex-extracted
Perfluorononanoic acid impedes mouse oocyte maturation by inducing mitochondrial dysfunction and oxidative stress
inferredcites →https://doi.org/10.1016/j.scitotenv.2018.04.380openalex-extracted
A short review on human exposure to and tissue distribution of per- and polyfluoroalkyl substances (PFASs)
inferredcites →https://doi.org/10.1016/j.scitotenv.2021.146399openalex-extracted
Exposure, health effects, sensing, and remediation of the emerging PFAS contaminants – Scientific challenges and potential research directions
inferredcites →https://doi.org/10.1016/j.scitotenv.2023.163123openalex-extracted
Environmental and health impacts of PFAS: Sources, distribution and sustainable management in North Carolina (USA)
inferredcites →https://doi.org/10.1016/j.scitotenv.2023.167392openalex-extracted
Binding interaction of environmental DNA with typical emerging perfluoroalkyl acids and its impact on bioavailability
inferredcites →https://doi.org/10.1016/j.tox.2022.153312openalex-extracted
Investigating the cytotoxicity of per- and polyfluoroalkyl substances in HepG2 cells: A structure-activity relationship approach
inferredcites →https://doi.org/10.1016/j.ymgme.2012.03.017openalex-extracted
The spectrum of pyruvate dehydrogenase complex deficiency: Clinical, biochemical and genetic features in 371 patients
inferredcites →https://doi.org/10.1016/j.yrtph.2010.09.008openalex-extracted
Toxicological evaluation of ammonium 4,8-dioxa-3H-perfluorononanoate, a new emulsifier to replace ammonium perfluorooctanoate in fluoropolymer manufacturing
inferredcites →https://doi.org/10.1021/acs.chemrestox.2c00072openalex-extracted
Neurotransmission Targets of Per- and Polyfluoroalkyl Substance Neurotoxicity: Mechanisms and Potential Implications for Adverse Neurological Outcomes
inferredcites →https://doi.org/10.1021/acs.chemrestox.2c00211openalex-extracted
Investigation of the Interaction between Human Serum Albumin and Branched Short-Chain Perfluoroalkyl Compounds
inferredcites →https://doi.org/10.1021/acs.est.3c04561openalex-extracted
Metabolic Perturbations Associated with an Exposure Mixture of Per- and Polyfluoroalkyl Substances in the Atlanta African American Maternal-Child Cohort
inferredcites →https://doi.org/10.1021/acs.est.7b04290openalex-extracted
Haloacetic Acid Water Disinfection Byproducts Affect Pyruvate Dehydrogenase Activity and Disrupt Cellular Metabolism
inferredcites →https://doi.org/10.1021/acs.estlett.0c00255openalex-extracted
Scientific Basis for Managing PFAS as a Chemical Class
inferredcites →https://doi.org/10.1038/cddis.2016.105openalex-extracted
ROS homeostasis and metabolism: a dangerous liason in cancer cells
inferredcites →https://doi.org/10.1038/s41370-018-0094-1openalex-extracted
A review of the pathways of human exposure to poly- and perfluoroalkyl substances (PFASs) and present understanding of health effects
inferredcites →https://doi.org/10.1038/s41598-018-19930-wopenalex-extracted
Mitochondrial biogenesis and metabolic hyperactivation limits the application of MTT assay in the estimation of radiation induced growth inhibition
inferredcites →https://doi.org/10.1038/srep38039openalex-extracted
Occurrence, temporal trends, and half-lives of perfluoroalkyl acids (PFAAs) in occupational workers in China
inferredcites →https://doi.org/10.1039/d0em00291gopenalex-extracted
An overview of the uses of per- and polyfluoroalkyl substances (PFAS)
inferredcites →https://doi.org/10.1080/21655979.2021.1972781openalex-extracted
Enzymatic characterization of D-lactate dehydrogenase and application in alanine aminotransferase activity assay kit
inferredcites →https://doi.org/10.1089/ars.2015.6311openalex-extracted
Metabolic Alterations Induce Oxidative Stress in Diabetic and Failing Hearts: Different Pathways, Same Outcome
inferredcites →https://doi.org/10.1093/toxsci/kfq066openalex-extracted
The Role of Nrf2 and MAPK Pathways in PFOS-Induced Oxidative Stress in Zebrafish Embryos
inferredcites →https://doi.org/10.1097/jom.0b013e3181965d80openalex-extracted
Thirty Years of Medical Surveillance in Perfluooctanoic Acid Production Workers
inferredcites →https://doi.org/10.1098/rsbl.2015.0538openalex-extracted
Individuals with higher metabolic rates have lower levels of reactive oxygen species in vivo
inferredcites →https://doi.org/10.1111/j.1742-4658.2007.06115.xopenalex-extracted
The lactate dehydrogenases encoded by the ldh and ldhB genes in Lactococcus lactis exhibit distinct regulation and catalytic properties − comparative modeling to probe the molecular basis
inferredcites →https://doi.org/10.1136/oemed-2017-104651openalex-extracted
Half-lives of PFOS, PFHxS and PFOA after end of exposure to contaminated drinking water
inferredcites →https://doi.org/10.1155/2012/217037openalex-extracted
Reactive Oxygen Species, Oxidative Damage, and Antioxidative Defense Mechanism in Plants under Stressful Conditions
inferredcites →https://doi.org/10.1155/2014/908539openalex-extracted
Oxidative Stress and Metabolic Pathologies: From an Adipocentric Point of View
inferredcites →https://doi.org/10.1155/2017/8416763openalex-extracted
Oxidative Stress: Harms and Benefits for Human Health
inferredcites →https://doi.org/10.1161/circresaha.117.311401openalex-extracted
Reactive Oxygen Species in Metabolic and Inflammatory Signaling
inferredcites →https://doi.org/10.1177/0192623308318208openalex-extracted
Gene Profiling in the Livers of Wild-type and PPARα-Null Mice Exposed to Perfluorooctanoic Acid
inferredcites →https://doi.org/10.1186/1559-0275-8-7openalex-extracted
Aberrant glycosylation associated with enzymes as cancer biomarkers
inferredcites →https://doi.org/10.1186/s12903-020-01306-0openalex-extracted
Serum and salivary levels of lactate dehydrogenase in oral squamous cell carcinoma, oral lichen planus and oral lichenoid reaction
inferredcites →https://doi.org/10.1186/s13023-020-01586-3openalex-extracted
Pyruvate dehydrogenase complex deficiency: updating the clinical, metabolic and mutational landscapes in a cohort of Portuguese patients
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Lactate: a multifunctional signaling molecule
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inferredcites →https://doi.org/10.1289/ehp.1509912openalex-extracted
Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis
inferredcites →https://doi.org/10.1289/ehp11372openalex-extracted
Metabolic Signatures of Youth Exposure to Mixtures of Per- and Polyfluoroalkyl Substances: A Multi-Cohort Study
inferredcites →https://doi.org/10.1289/ehp5843openalex-extracted
Evaluation of Developmental Toxicity, Developmental Neurotoxicity, and Tissue Dose in Zebrafish Exposed to GenX and Other PFAS
inferredcites →https://doi.org/10.1289/isee.2022.o-op-026openalex-extracted
The Devil they knew: chemical documents analysis of industry influence on PFAS Science
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Catalase, a remarkable enzyme: targeting the oldest antioxidant enzyme to find a new cancer treatment approach
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Pyruvate Dehydrogenase and Pyruvate Dehydrogenase Kinase Expression in Non Small Cell Lung Cancer and Tumor-Associated Stroma
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Decreased Catalase Expression and Increased Susceptibility to Oxidative Stress in Primary Cultured Corneal Fibroblasts from Patients with Granular Corneal Dystrophy Type II
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Glutathione level and glutathione reductase activity in serum of coronary heart disease patients
inferredcites →https://doi.org/10.3389/fmats.2023.1143411openalex-extracted
Firefighters’ exposure to per-and polyfluoroalkyl substances (PFAS) as an occupational hazard: A review
inferredcites →https://doi.org/10.3389/fphar.2014.00196openalex-extracted
Glutathione: new roles in redox signaling for an old antioxidant
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Association between perfluoroalkyl and polyfluoroalkyl internal exposure and serum α-Klotho levels in middle-old aged participants
inferredcites →https://doi.org/10.3389/ftox.2021.732436openalex-extracted
A Review of Per- and Polyfluorinated Alkyl Substance Impairment of Reproduction
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A Review of the Applications, Environmental Release, and Remediation Technologies of Per- and Polyfluoroalkyl Substances
inferredcites →https://doi.org/10.3390/ijms22094642openalex-extracted
The Chemistry of Reactive Oxygen Species (ROS) Revisited: Outlining Their Role in Biological Macromolecules (DNA, Lipids and Proteins) and Induced Pathologies
inferredcites →https://doi.org/10.3390/nu13113902openalex-extracted
Per- and Polyfluoroalkyl Substance Exposure Combined with High-Fat Diet Supports Prostate Cancer Progression
inferredcites →https://doi.org/10.3390/toxics10020044openalex-extracted
PFAS Molecules: A Major Concern for the Human Health and the Environment
inferredcites →https://doi.org/10.3390/toxics10020091openalex-extracted
Early Warnings by Liver Organoids on Short- and Long-Chain PFAS Toxicity
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Redox status expressed as GSH:GSSG ratio as a marker for oxidative stress in paediatric tumour patients
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Endogenous Antioxidants: A Review of their Role in Oxidative Stress
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Exploring the medicinal potential of in vitro cultures for enhanced production of metabolite empowered by green silver nanoparticles in Alhagi maurorum medik
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