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Synthesis and Bioactivity Evaluation of Glucosylated Resveratrol Derivatives as New Antioxidative Neuroprotection Agents Against Cerebral Ischemia-Reperfusion Injury

https://doi.org/10.2139/ssrn.4836594
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Resveratrol: A miraculous natural compound for diseases treatment
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Structural and functional aspects of the blood-brain barrier
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The High Cost of Stroke and Stroke Cytoprotection Research
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Mesenchymal stem cell-derived extracellular vesicles attenuate tPA-induced blood–brain barrier disruption in murine ischemic stroke models
inferredcites →https://doi.org/10.1016/j.arabjc.2023.105393openalex-extracted
Resveratrol-loaded copolymer nanoparticles with anti-neurological impairment, antioxidant and anti-inflammatory activities against cerebral ischemia–reperfusion injury
inferredcites →https://doi.org/10.1016/j.biopha.2023.114671openalex-extracted
The role of mitochondrial dynamics in cerebral ischemia-reperfusion injury
inferredcites →https://doi.org/10.1016/j.cmet.2008.06.011openalex-extracted
Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span
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Design, synthesis and biological evaluation of multivalent glucosides with high affinity as ligands for brain targeting liposomes
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PARP-1 inhibitor alleviates cerebral ischemia/reperfusion injury by reducing PARylation of HK-1 and LDH in mice
inferredcites →https://doi.org/10.1016/j.expneurol.2024.114727openalex-extracted
The paradox of tPA in ischemic stroke: tPA knockdown following recanalization improves functional and histological outcomes
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Oxidative DNA damage protective activity, antioxidant and anti-quorum sensing potentials of Moringa oleifera
inferredcites →https://doi.org/10.1016/j.fitote.2024.105872openalex-extracted
Synthesis, biological evaluation and docking studies of N-substituted resveratrol derivatives
inferredcites →https://doi.org/10.1016/j.intimp.2021.108040openalex-extracted
Neuroprotective effects of methylcobalamin in cerebral ischemia/reperfusion injury through activation of the ERK1/2 signaling pathway
inferredcites →https://doi.org/10.1016/j.neuroscience.2023.12.016openalex-extracted
Effect of the Novel Free Radical Scavenger 4′-Hydroxyl-2-Substituted Phenylnitronyl Nitroxide on Oxidative Stress, Mitochondrial Dysfunction and Apoptosis Induced by Cerebral Ischemia–Reperfusion in Rats
inferredcites →https://doi.org/10.1016/s0008-6215(96)00328-xopenalex-extracted
Synthesis of O-methylsulfonyl derivatives of d-glucose as potential alkylating agents for targeted drug delivery to the brain. Evaluation of their interaction with the human erythrocyte GLUT1 hexose transporter
inferredcites →https://doi.org/10.1016/s0140-6736(20)31179-xopenalex-extracted
Stroke
inferredcites →https://doi.org/10.1016/s1474-4422(18)30500-3openalex-extracted
Stroke in China: advances and challenges in epidemiology, prevention, and management
inferredcites →https://doi.org/10.1021/acs.jafc.1c02602openalex-extracted
Dual Strategy for Improving the Oral Bioavailability of Resveratrol: Enhancing Water Solubility and Inhibiting Glucuronidation
inferredcites →https://doi.org/10.1021/acs.jafc.6b01513openalex-extracted
Green Tea Catechin Prevents Hypoxia/Reperfusion-Evoked Oxidative Stress-Regulated Autophagy-Activated Apoptosis and Cell Death in Microglial Cells
inferredcites →https://doi.org/10.1021/acs.jafc.7b03129openalex-extracted
Lipophilization of Resveratrol and Effects on Antioxidant Activities
inferredcites →https://doi.org/10.1021/acs.jafc.9b05963openalex-extracted
Resveratrol and Oxyresveratrol Activate Thermogenesis via Different Transcriptional Coactivators in High-Fat Diet-Induced Obese Mice
inferredcites →https://doi.org/10.1021/ja020531iopenalex-extracted
Acid-Promoted DNA-Cleaving Activities and Total Synthesis of Varacin C
inferredcites →https://doi.org/10.1021/jf101472nopenalex-extracted
Antioxidant Activity of Resveratrol in Several Fish Lipid Matrices: Effect of Acylation and Glucosylation
inferredcites →https://doi.org/10.1021/jf204909popenalex-extracted
Neuroprotective Effects of Xanthohumol, a Prenylated Flavonoid from Hops (Humulus lupulus), in Ischemic Stroke of Rats
inferredcites →https://doi.org/10.1021/jf303771sopenalex-extracted
Antioxidant and DNA-Protective Activities of Chlorogenic Acid Isomers
inferredcites →https://doi.org/10.1021/jf400203hopenalex-extracted
Effects of Bilberry (Vaccinium myrtillus) in Combination with Lactic Acid Bacteria on Intestinal Oxidative Stress Induced by Ischemia–Reperfusion in Mouse
inferredcites →https://doi.org/10.1021/jf404155eopenalex-extracted
Improved Stability of trans-Resveratrol in Aqueous Solutions by Carboxymethylated (1,3/1,6)-β- d -Glucan
inferredcites →https://doi.org/10.1021/jf800752sopenalex-extracted
Antioxidant Protection of Resveratrol and Catechin inSaccharomyces cerevisiae
inferredcites →https://doi.org/10.1021/jm1007006openalex-extracted
Preventive Oral Treatment with Resveratrol Pro-prodrugs Drastically Reduce Colon Inflammation in Rodents
inferredcites →https://doi.org/10.1038/nrd.2015.21openalex-extracted
From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery
inferredcites →https://doi.org/10.1038/s41573-021-00139-yopenalex-extracted
Strategies for delivering therapeutics across the blood–brain barrier
inferredcites →https://doi.org/10.1074/jbc.m101846200openalex-extracted
Specific Structural Determinants Are Responsible for the Antioxidant Activity and the Cell Cycle Effects of Resveratrol
inferredcites →https://doi.org/10.1096/fasebj.9.7.7737461openalex-extracted
Oxidative processes and antioxidative defense mechanisms in the aging brain 1
inferredcites →https://doi.org/10.1155/2010/205357openalex-extracted
Potential Role of Sugar Transporters in Cancer and Their Relationship with Anticancer Therapy
inferredcites →https://doi.org/10.1159/000512367openalex-extracted
The Protective and Reparative Role of Colony-Stimulating Factors in the Brain with Cerebral Ischemia/Reperfusion Injury
inferredcites →https://doi.org/10.1161/circresaha.120.317596openalex-extracted
tPA Mobilizes Immune Cells That Exacerbate Hemorrhagic Transformation in Stroke
inferredcites →https://doi.org/10.1182/bloodadvances.2023011744openalex-extracted
Improving stroke outcomes in hyperglycemic mice by modulating tPA/NMDAR signaling to reduce inflammation and hemorrhages
inferredcites →https://doi.org/10.1371/journal.pone.0013741openalex-extracted
The Mouse Blood-Brain Barrier Transcriptome: A New Resource for Understanding the Development and Function of Brain Endothelial Cells
inferredcites →https://doi.org/10.1371/journal.pone.0087865openalex-extracted
Co-Administration of Resveratrol and Lipoic Acid, or Their Synthetic Combination, Enhances Neuroprotection in a Rat Model of Ischemia/Reperfusion
inferredcites →https://doi.org/10.1586/14737175.2015.1035712openalex-extracted
Systemic inflammation as a therapeutic target in acute ischemic stroke
inferredcites →https://doi.org/10.3892/mmr.2019.10723openalex-extracted
Effects of resveratrol on learning and memory in rats with vascular dementia
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