On the public citation graph

Dual-Action Metronidazole-5-Nitrodihydroeugenol Hybrid: Reduces Parasitism, Cardiac Risk, and Inflammatory Response, While Boosting Benznidazole Efficacy

https://doi.org/10.2139/ssrn.5240565
0 signed · 35 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.
Claim with ORCID
Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.
See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1006/expr.2000.4576openalex-snapshot
Trypanosoma cruzi: Peripheral Blood Monocytes and Heart Macrophages in the Resistance to Acute Experimental Infection in Rats
inferredcites →https://doi.org/10.1007/s00436-015-4488-xopenalex-snapshot
Trypanosoma cruzi infection and benznidazole therapy independently stimulate oxidative status and structural pathological remodeling of the liver tissue in mice
inferredcites →https://doi.org/10.1016/0035-9203(87)90020-4openalex-snapshot
Susceptibility and natural resistance of Trypanosoma cruzi strains to drugs used clinically in Chagas disease
inferredcites →https://doi.org/10.1016/0169-4758(95)80095-6openalex-snapshot
The role of T cells in Trypanosoma cruzi infections
inferredcites →https://doi.org/10.1016/b978-0-12-385895-5.00010-4openalex-snapshot
Adipose Tissue, Diabetes and Chagas Disease
inferredcites →https://doi.org/10.1016/j.ajpath.2012.11.027openalex-snapshot
Alterations in Glucose Homeostasis in a Murine Model of Chagas Disease
inferredcites →https://doi.org/10.1016/j.bbi.2012.07.009openalex-snapshot
Trypanosoma cruzi-induced depressive-like behavior is independent of meningoencephalitis but responsive to parasiticide and TNF-targeted therapeutic interventions
inferredcites →https://doi.org/10.1016/j.bcp.2017.08.025openalex-snapshot
Drug repurposing strategy against Trypanosoma cruzi infection: In vitro and in vivo assessment of the activity of metronidazole in mono- and combined therapy
inferredcites →https://doi.org/10.1016/j.bcp.2018.01.005openalex-snapshot
Time and dose-dependence evaluation of nitroheterocyclic drugs for improving efficacy following Trypanosoma cruzi infection: A pre-clinical study
inferredcites →https://doi.org/10.1016/j.bioorg.2024.107288openalex-snapshot
Synthesis of new trypanocidal agents from the hybridisation of metronidazole and eugenol analogues
inferredcites →https://doi.org/10.1016/j.ijpddr.2015.10.001openalex-snapshot
Development and application of a sensitive, phenotypic, high-throughput image-based assay to identify compound activity against Trypanosoma cruzi amastigotes
inferredcites →https://doi.org/10.1016/j.jep.2006.10.036openalex-snapshot
In vitro antiprotozoal activities and cytotoxicity of some selected Cameroonian medicinal plants
inferredcites →https://doi.org/10.1016/j.micinf.2007.10.009openalex-snapshot
Etiological treatment during early chronic indeterminate Chagas disease incites an activated status on innate and adaptive immunity associated with a type 1-modulated cytokine pattern
inferredcites →https://doi.org/10.1016/s0166-6851(03)00093-8openalex-snapshot
Rapid quantitation of Trypanosoma cruzi in host tissue by real-time PCR
inferredcites →https://doi.org/10.1038/356338a0openalex-snapshot
Susceptibility of β2-microglobulin-deficient mice to Trypanosoma cruzi infection
inferredcites →https://doi.org/10.1046/j.1365-3024.1998.00154.xopenalex-snapshot
The relative contribution of antibody production and CD8+ T cell function to immune control of Trypanosoma cruzi
inferredcites →https://doi.org/10.1074/jbc.m412802200openalex-snapshot
The Adipocyte as an Important Target Cell for Trypanosoma cruzi Infection
inferredcites →https://doi.org/10.1080/1040841x.2017.1295225openalex-snapshot
Antimicrobial activity of eugenol and essential oils containing eugenol: A mechanistic viewpoint
inferredcites →https://doi.org/10.1080/14656566.2019.1650915openalex-snapshot
An evaluation of benznidazole as a Chagas disease therapeutic
inferredcites →https://doi.org/10.1086/503812openalex-snapshot
Chemokine CC Receptor 2 Is Important for Acute Control of Cardiac Parasitism but Does Not Contribute to Cardiac Inflammation after Infection withTrypanosoma cruzi
inferredcites →https://doi.org/10.1093/jac/dkz473openalex-snapshot
Tolerance to nifurtimox and benznidazole in adult patients with chronic Chagas’ disease
inferredcites →https://doi.org/10.1111/j.1365-2613.2009.00670.xopenalex-snapshot
Perforin‐expressing cytotoxic cells contribute to chronic cardiomyopathy in Trypanosoma cruzi infection
inferredcites →https://doi.org/10.1111/j.1462-5822.2012.01764.xopenalex-snapshot
Mechanisms of Trypanosoma cruzi persistence in Chagas disease
inferredcites →https://doi.org/10.1128/iai.74.1.135-143.2006openalex-snapshot
The CC Chemokine Receptor 5 Is Important in Control of Parasite Replication and Acute Cardiac Inflammation following Infection withTrypanosoma cruzi
inferredcites →https://doi.org/10.1371/journal.pntd.0010386openalex-snapshot
Use of benznidazole to treat chronic Chagas disease: An updated systematic review with a meta-analysis
inferredcites →https://doi.org/10.1371/journal.pone.0128707openalex-snapshot
Benznidazole/Itraconazole Combination Treatment Enhances Anti-Trypanosoma cruzi Activity in Experimental Chagas Disease
inferredcites →https://doi.org/10.1371/journal.ppat.1002645openalex-snapshot
CD8+ T-Cells Expressing Interferon Gamma or Perforin Play Antagonistic Roles in Heart Injury in Experimental Trypanosoma Cruzi-Elicited Cardiomyopathy
inferredcites →https://doi.org/10.1517/13543784.2014.922952openalex-snapshot
Therapeutical approaches under investigation for treatment of Chagas disease
inferredcites →https://doi.org/10.1590/s0100-879x1998000100018openalex-snapshot
Cytokine production profile of heart-infiltrating T cells in Chagas' disease cardiomyopathy
inferredcites →https://doi.org/10.1590/s0102-695x2009000200006openalex-snapshot
Anti-inflammatory and antinociceptive activities A of eugenol essential oil in experimental animal models
inferredcites →https://doi.org/10.2174/0929867325666180111101843openalex-snapshot
Multi-Target Directed Drugs as a Modern Approach for Drug Design Towards Alzheimer’s Disease: An Update
inferredcites →https://doi.org/10.2174/156652408785748004openalex-snapshot
Chagas Heart Disease Pathogenesis: One Mechanism or Many?
inferredcites →https://doi.org/10.2217/fmb.11.122openalex-snapshot
The Role of Toll-Like Receptors and Adaptive Immunity in the Development of Protective or Pathological Immune Response Triggered by the Trypanosoma Cruzi Protozoan
inferredcites →https://doi.org/10.26355/eurrev_201901_16788openalex-snapshot
Therapeutic uses of metronidazole and its side effects: an update.
inferredcites →https://doi.org/10.4067/s0716-97602010000300009openalex-snapshot
Chagas disease: Present status of pathogenic mechanisms and chemotherapy
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.