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Overactive BRCA1 Affects Presenilin 1 in Induced Pluripotent Stem Cell-Derived Neurons in Alzheimer’s Disease
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/bies.20277openalex-snapshot
Regulation of BRCA1, BRCA2 and BARD1 intracellular trafficking
inferredcites →https://doi.org/10.1007/s12013-013-9634-4openalex-snapshot
Neuronal Ubiquitin Homeostasis
inferredcites →https://doi.org/10.1007/s12035-016-0105-yopenalex-snapshot
Familial Alzheimer’s Disease Lymphocytes Respond Differently Than Sporadic Cells to Oxidative Stress: Upregulated p53-p21 Signaling Linked with Presenilin 1 Mutants
inferredcites →https://doi.org/10.1007/s12640-011-9277-4openalex-snapshot
Role of Cell Cycle Re-Entry in Neurons: A Common Apoptotic Mechanism of Neuronal Cell Death
inferredcites →https://doi.org/10.1007/s12640-014-9514-8openalex-snapshot
Toxic Effects of Bortezomib on Primary Sensory Neurons and Schwann Cells of Adult Mice
inferredcites →https://doi.org/10.1007/s13238-010-0010-5openalex-snapshot
The role of BRCA1 in DNA damage response
inferredcites →https://doi.org/10.1016/j.bbadis.2006.10.016openalex-snapshot
The nature of the cell cycle in neurons: Focus on a “non-canonical” pathway of DNA replication causally related to death
inferredcites →https://doi.org/10.1016/j.bbagen.2006.02.006openalex-snapshot
Normal distribution of presenilin-1 and nicastrin in skeletal muscle and the differential responses of these proteins after denervation
inferredcites →https://doi.org/10.1016/j.expneurol.2006.01.022openalex-snapshot
Two novel presenilin 1 gene mutations connected with frontotemporal dementia-like clinical phenotype: Genetic and bioinformatic assessment
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2012.07.018openalex-snapshot
Sporadic Alzheimer disease fibroblasts display an oxidative stress phenotype
inferredcites →https://doi.org/10.1016/j.jalz.2011.05.229openalex-snapshot
O1‐01‐07: Whole transcriptome changes in the prefrontal cortex of late‐onset Alzheimer's disease patients
inferredcites →https://doi.org/10.1016/j.mcn.2011.05.004openalex-snapshot
Centrosomes, microtubules and neuronal development
inferredcites →https://doi.org/10.1016/j.mrfmmm.2014.11.010openalex-snapshot
DNA damage in neurodegenerative diseases
inferredcites →https://doi.org/10.1016/j.scr.2016.09.028openalex-snapshot
Generation of human iPS cell line CTL07-II from human fibroblasts, under defined and xeno-free conditions
inferredcites →https://doi.org/10.1016/j.yexcr.2006.06.008openalex-snapshot
Structure meets function—Centrosomes, genome maintenance and the DNA damage response
inferredcites →https://doi.org/10.1016/s0006-8993(01)03146-8openalex-snapshot
Age-related changes in the localization of presenilin-1 in cynomolgus monkey brain
inferredcites →https://doi.org/10.1016/s0092-8674(00)80356-6openalex-snapshot
Alzheimer Presenilins in the Nuclear Membrane, Interphase Kinetochores, and Centrosomes Suggest a Role in Chromosome Segregation
inferredcites →https://doi.org/10.1038/bjc.2015.208openalex-snapshot
Association between cytosolic expression of BRCA1 and metastatic risk in breast cancer
inferredcites →https://doi.org/10.1038/cddis.2014.537openalex-snapshot
Suppression of BRCA1 sensitizes cells to proteasome inhibitors
inferredcites →https://doi.org/10.1038/gim.2015.117openalex-snapshot
The genetic landscape of Alzheimer disease: clinical implications and perspectives
inferredcites →https://doi.org/10.1038/ncomms9897openalex-snapshot
DNA repair factor BRCA1 depletion occurs in Alzheimer brains and impairs cognitive function in mice
inferredcites →https://doi.org/10.1038/ng837openalex-snapshot
BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage
inferredcites →https://doi.org/10.1038/sj.onc.1200924openalex-snapshot
Differential subcellular localization, expression and biological toxicity of BRCA1 and the splice variant BRCA1-Δ11b
inferredcites →https://doi.org/10.1038/sj.onc.1209872openalex-snapshot
The role of BRCA1 in transcriptional regulation and cell cycle control
inferredcites →https://doi.org/10.1042/bst20120140openalex-snapshot
BRCA1 exon 11 alternative splicing, multiple functions and the association with cancer
inferredcites →https://doi.org/10.1073/pnas.0401847101openalex-snapshot
Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation
inferredcites →https://doi.org/10.1073/pnas.1400783111openalex-snapshot
Role of BRCA1 in brain development
inferredcites →https://doi.org/10.1074/jbc.275.4.2777openalex-snapshot
BRCA1 Effects on the Cell Cycle and the DNA Damage Response Are Linked to Altered Gene Expression
inferredcites →https://doi.org/10.1074/jbc.m114.611186openalex-snapshot
The BRCA1 Tumor Suppressor Binds to Inositol 1,4,5-Trisphosphate Receptors to Stimulate Apoptotic Calcium Release
inferredcites →https://doi.org/10.1080/15384101.2015.1004937openalex-snapshot
Neuronal cell cycle: the neuron itself and its circumstances
inferredcites →https://doi.org/10.1089/omi.2011.0054openalex-snapshot
Integrating the Alzheimer's Disease Proteome and Transcriptome: A Comprehensive Network Model of a Complex Disease
inferredcites →https://doi.org/10.1089/rej.2015.1717openalex-snapshot
Role of the Cell Cycle Re-Initiation in DNA Damage Response of Post-Mitotic Cells and Its Implication in the Pathogenesis of Neurodegenerative Diseases
inferredcites →https://doi.org/10.1093/bioinformatics/btr174openalex-snapshot
BamTools: a C++ API and toolkit for analyzing and managing BAM files
inferredcites →https://doi.org/10.1093/bioinformatics/bts635openalex-snapshot
STAR: ultrafast universal RNA-seq aligner
inferredcites →https://doi.org/10.1093/bioinformatics/btt285openalex-snapshot
Pathview: an R/Bioconductor package for pathway-based data integration and visualization
inferredcites →https://doi.org/10.1093/bioinformatics/btt656openalex-snapshot
featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
inferredcites →https://doi.org/10.1093/bioinformatics/btu170openalex-snapshot
Trimmomatic: a flexible trimmer for Illumina sequence data
inferredcites →https://doi.org/10.1093/hmg/ddm305openalex-snapshot
ubiquilin antagonizes presenilin and promotes neurodegeneration in Drosophila
inferredcites →https://doi.org/10.1093/nar/gkl010openalex-snapshot
BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution
inferredcites →https://doi.org/10.1093/nar/gkv350openalex-snapshot
The BioMart community portal: an innovative alternative to large, centralized data repositories
inferredcites →https://doi.org/10.1093/nar/gkw1092openalex-snapshot
KEGG: new perspectives on genomes, pathways, diseases and drugs
inferredcites →https://doi.org/10.1096/fj.02-0980fjeopenalex-snapshot
Microtubular interactions of presenilin direct kinesis of Aβ peptide and its precursors
inferredcites →https://doi.org/10.1111/j.1600-0854.2010.01149.xopenalex-snapshot
Alzheimer's Disease‐Associated Ubiquilin‐1 Regulates Presenilin‐1 Accumulation and Aggresome Formation
inferredcites →https://doi.org/10.1128/mcb.21.12.4005-4015.2001openalex-snapshot
Impaired DNA Damage Response in Cells Expressing an Exon 11-Deleted Murine Brca1 Variant That Localizes to Nuclear Foci
inferredcites →https://doi.org/10.1128/mcb.24.19.8457-8466.2004openalex-snapshot
BRCA1-Dependent Ubiquitination of γ-Tubulin Regulates Centrosome Number
inferredcites →https://doi.org/10.1158/0008-5472.can-05-4430openalex-snapshot
Identification of Domains of BRCA1 Critical for the Ubiquitin-Dependent Inhibition of Centrosome Function
inferredcites →https://doi.org/10.1158/0008-5472.can-10-3119openalex-snapshot
Bcl-2 Inhibits Nuclear Homologous Recombination by Localizing BRCA1 to the Endomembranes
inferredcites →https://doi.org/10.1179/1743132813y.0000000288openalex-snapshot
Relationship between amyloid-beta and the ubiquitin–proteasome system in Alzheimer’s disease
inferredcites →https://doi.org/10.1186/1471-2105-10-161openalex-snapshot
GAGE: generally applicable gene set enrichment for pathway analysis
inferredcites →https://doi.org/10.1186/1471-2105-7-85openalex-snapshot
Statistical analysis of real-time PCR data
inferredcites →https://doi.org/10.1186/1747-1028-3-1openalex-snapshot
The ubiquitin E3 ligase activity of BRCA1 and its biological functions
inferredcites →https://doi.org/10.1186/gb-2009-10-3-r25openalex-snapshot
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
inferredcites →https://doi.org/10.1186/gb-2010-11-10-r106openalex-snapshot
Differential expression analysis for sequence count data
inferredcites →https://doi.org/10.1186/gb-2010-11-2-106openalex-snapshot
The pea aphid genome sequence brings theories of insect defense into question
inferredcites →https://doi.org/10.1186/s12859-015-0778-7openalex-snapshot
Comparing the normalization methods for the differential analysis of Illumina high-throughput RNA-Seq data
inferredcites →https://doi.org/10.1186/s12859-016-0994-9openalex-snapshot
Sample size calculation while controlling false discovery rate for differential expression analysis with RNA-sequencing experiments
inferredcites →https://doi.org/10.1186/s13059-014-0550-8openalex-snapshot
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
inferredcites →https://doi.org/10.1186/s13195-014-0073-2openalex-snapshot
Alpha-synuclein biology in Lewy body diseases
inferredcites →https://doi.org/10.1371/journal.pone.0016266openalex-snapshot
Whole Transcriptome Sequencing Reveals Gene Expression and Splicing Differences in Brain Regions Affected by Alzheimer's Disease
inferredcites →https://doi.org/10.1371/journal.pone.0029597openalex-snapshot
Capture of Neuroepithelial-Like Stem Cells from Pluripotent Stem Cells Provides a Versatile System for In Vitro Production of Human Neurons
inferredcites →https://doi.org/10.1371/journal.pone.0061074openalex-snapshot
A Patient with Posterior Cortical Atrophy Possesses a Novel Mutation in the Presenilin 1 Gene
inferredcites →https://doi.org/10.1371/journal.pone.0154531openalex-snapshot
Conserved Senescence Associated Genes and Pathways in Primary Human Fibroblasts Detected by RNA-Seq
inferredcites →https://doi.org/10.1523/jneurosci.2593-06.2006openalex-snapshot
The Chk1/Cdc25A Pathway as Activators of the Cell Cycle in Neuronal Death Induced by Camptothecin
inferredcites →https://doi.org/10.1534/genetics.104.035170openalex-snapshot
Presenilin-Based Genetic Screens in Drosophila melanogaster Identify Novel Notch Pathway Modifiers
inferredcites →https://doi.org/10.2119/2007-00100.irvineopenalex-snapshot
Protein Aggregation in the Brain: The Molecular Basis for Alzheimer’s and Parkinson’s Diseases
inferredcites →https://doi.org/10.3233/jad-121963openalex-snapshot
Characteristic Transformation of Blood Transcriptome in Alzheimer's Disease
inferredcites →https://doi.org/10.3233/jad-141977openalex-snapshot
Oxidative Stress and Aberrant Cell Cycle in Alzheimer’s Disease Lymphocytes: Diagnostic Prospects
inferredcites →https://doi.org/10.3389/fnins.2016.00178openalex-snapshot
Alzheimer's Disease and Hippocampal Adult Neurogenesis; Exploring Shared Mechanisms
inferredcites →https://doi.org/10.3390/ijms16022879openalex-snapshot
BRCA1 and p53 Tumor Suppressor Molecules in Alzheimer’s Disease
inferredcites →https://doi.org/10.3892/br.2015.523openalex-snapshot
Bortezomib and belinostat inhibit renal cancer growth synergistically by causing ubiquitinated protein accumulation and endoplasmic reticulum stress
inferredcites →https://doi.org/10.4161/cc.21396openalex-snapshot
Analysis of centrosome localization of BRCA1 and its activity in suppressing centrosomal aster formation
inferredcites →https://doi.org/10.55782/ane-2009-1748openalex-snapshot
Aneuploidy, chromosomal missegregation, and cell cycle reentry in Alzheimer's disease
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Human-Induced Pluripotent Stem Cell–Based Models for Studying Sex-Specific Differences in Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.1007/s10571-023-01337-5openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s12015-021-10254-3openalex-snapshot
Human iPSC-Derived Neural Models for Studying Alzheimer’s Disease: from Neural Stem Cells to Cerebral Organoids
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inferred← citeshttps://doi.org/10.1016/j.bbadis.2019.03.004openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.celrep.2023.113310openalex-snapshot
Cerebral organoids derived from patients with Alzheimer’s disease with PSEN1/2 mutations have defective tissue patterning and altered development
inferred← citeshttps://doi.org/10.1016/j.drudis.2019.01.007openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.gerinurse.2024.04.019openalex-snapshot
Comorbidities in patients with vascular dementia and Alzheimer's disease with Neuropsychiatric symptoms
inferred← citeshttps://doi.org/10.1016/j.jalz.2018.08.013openalex-snapshot
CDT2‐controlled cell cycle reentry regulates the pathogenesis of Alzheimer's disease
inferred← citeshttps://doi.org/10.1016/j.jare.2023.01.006openalex-snapshot
Alzheimer's disease and synapse Loss: What can we learn from induced pluripotent stem Cells?
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Engrafted stem cell therapy for Alzheimer's disease: A promising treatment strategy with clinical outcome
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inferred← citeshttps://doi.org/10.1016/j.pneurobio.2020.101804openalex-snapshot
The Use of Patient-Derived Induced Pluripotent Stem Cells for Alzheimer’s Disease Modeling
inferred← citeshttps://doi.org/10.1021/acschemneuro.8b00149openalex-snapshot
Role of BRCA1 in Neuronal Death in Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1038/s41380-019-0468-3openalex-snapshot
Modeling Alzheimer’s disease with iPSC-derived brain cells
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