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Roles of Ipsc in Advancing Treatments for Neurological Disorders

https://doi.org/10.2139/ssrn.4818803
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inferredcites →https://doi.org/10.1001/jamanetworkopen.2019.1350openalex-extracted
Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry
inferredcites →https://doi.org/10.1002/emmm.201200215openalex-extracted
Disease‐specific phenotypes in dopamine neurons from human iPS‐based models of genetic and sporadic Parkinson's disease
inferredcites →https://doi.org/10.1002/glia.23761openalex-extracted
Mutant C9orf72 human iPSC‐derived astrocytes cause non‐cell autonomous motor neuron pathophysiology
inferredcites →https://doi.org/10.1002/stem.1334openalex-extracted
Efficient Generation of Astrocytes from Human Pluripotent Stem Cells in Defined Conditions
inferredcites →https://doi.org/10.1002/stem.1415openalex-extracted
Improved Cell Therapy Protocols for Parkinson's Disease Based on Differentiation Efficiency and Safety of hESC-, hiPSC-, and Non-Human Primate iPSC-Derived Dopaminergic Neurons
inferredcites →https://doi.org/10.1002/stem.2388openalex-extracted
C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
inferredcites →https://doi.org/10.1007/978-1-0716-1979-7_11openalex-extracted
Differentiation of iPS-Cells into Peripheral Sensory Neurons
inferredcites →https://doi.org/10.1007/978-1-4939-9477-9_3openalex-extracted
Generating Human iPSC-Derived Astrocytes with Chemically Defined Medium for In Vitro Disease Modeling
inferredcites →https://doi.org/10.1007/s00401-019-02083-zopenalex-extracted
Production of poly(GA) in C9ORF72 patient motor neurons derived from induced pluripotent stem cells
inferredcites →https://doi.org/10.1007/s00401-020-02252-5openalex-extracted
Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis
inferredcites →https://doi.org/10.1007/s13311-021-01115-5openalex-extracted
Screening Platforms for Genetic Epilepsies—Zebrafish, iPSC-Derived Neurons, and Organoids
inferredcites →https://doi.org/10.1007/s13311-022-01212-zopenalex-extracted
Luminescent Human iPSC-Derived Neurospheroids Enable Modeling of Neurotoxicity After Oxygen–glucose Deprivation
inferredcites →https://doi.org/10.1016/j.biomaterials.2017.10.002openalex-extracted
3D neural tissue models: From spheroids to bioprinting
inferredcites →https://doi.org/10.1016/j.cell.2006.07.024openalex-extracted
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
inferredcites →https://doi.org/10.1016/j.cell.2008.07.041openalex-extracted
Disease-Specific Induced Pluripotent Stem Cells
inferredcites →https://doi.org/10.1016/j.cell.2009.02.013openalex-extracted
Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors
inferredcites →https://doi.org/10.1016/j.cell.2011.06.019openalex-extracted
Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations
inferredcites →https://doi.org/10.1016/j.cell.2017.09.003openalex-extracted
Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation
inferredcites →https://doi.org/10.1016/j.cell.2020.11.017openalex-extracted
Generation of Functional Human 3D Cortico-Motor Assembloids
inferredcites →https://doi.org/10.1016/j.celrep.2014.03.019openalex-extracted
Intrinsic Membrane Hyperexcitability of Amyotrophic Lateral Sclerosis Patient-Derived Motor Neurons
inferredcites →https://doi.org/10.1016/j.celrep.2016.05.022openalex-extracted
Molecular Features Underlying Neurodegeneration Identified through In Vitro Modeling of Genetically Diverse Parkinson’s Disease Patients
inferredcites →https://doi.org/10.1016/j.celrep.2016.09.062openalex-extracted
Generating Late-Onset Human iPSC-Based Disease Models by Inducing Neuronal Age-Related Phenotypes through Telomerase Manipulation
inferredcites →https://doi.org/10.1016/j.celrep.2016.12.001openalex-extracted
Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain
inferredcites →https://doi.org/10.1016/j.celrep.2018.06.091openalex-extracted
Insights into the Mutational Burden of Human Induced Pluripotent Stem Cells from an Integrative Multi-Omics Approach
inferredcites →https://doi.org/10.1016/j.conb.2012.05.001openalex-extracted
Direct lineage reprogramming to neural cells
inferredcites →https://doi.org/10.1016/j.ebiom.2019.11.026openalex-extracted
Human iPSC-derived astrocytes from ALS patients with mutated C9ORF72 show increased oxidative stress and neurotoxicity
inferredcites →https://doi.org/10.1016/j.gene.2013.07.101openalex-extracted
Onset of rosette formation during spontaneous neural differentiation of hESC and hiPSC colonies
inferredcites →https://doi.org/10.1016/j.mcn.2006.11.008openalex-extracted
Human oligodendrocytes derived from embryonic stem cells: Effect of noggin on phenotypic differentiation in vitro and on myelination in vivo
inferredcites →https://doi.org/10.1016/j.nbd.2018.03.010openalex-extracted
Age-dependent neurodegeneration and organelle transport deficiencies in mutant TDP43 patient-derived neurons are independent of TDP43 aggregation
inferredcites →https://doi.org/10.1016/j.nbd.2019.104483openalex-extracted
The use of iPSC technology for modeling Autism Spectrum Disorders
inferredcites →https://doi.org/10.1016/j.nbd.2021.105391openalex-extracted
Modeling chemotherapy induced neurotoxicity with human induced pluripotent stem cell (iPSC) -derived sensory neurons
inferredcites →https://doi.org/10.1016/j.neulet.2019.134681openalex-extracted
Rapid differentiation of astrocytes from human embryonic stem cells
inferredcites →https://doi.org/10.1016/j.neuro.2018.06.007openalex-extracted
Human iPSC-derived neuronal models for in vitro neurotoxicity assessment
inferredcites →https://doi.org/10.1016/j.neuron.2011.09.010openalex-extracted
A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
inferredcites →https://doi.org/10.1016/j.neuron.2011.09.011openalex-extracted
Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
inferredcites →https://doi.org/10.1016/j.neuron.2013.05.029openalex-extracted
Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
inferredcites →https://doi.org/10.1016/j.neuron.2013.10.015openalex-extracted
RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention
inferredcites →https://doi.org/10.1016/j.neuron.2019.07.014openalex-extracted
CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons
inferredcites →https://doi.org/10.1016/j.neuron.2020.01.020openalex-extracted
Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity
inferredcites →https://doi.org/10.1016/j.reprotox.2023.108358openalex-extracted
Assessment of neurotransmitter release in human iPSC-derived neuronal/glial cells: a missing in vitro assay for regulatory developmental neurotoxicity testing
inferredcites →https://doi.org/10.1016/j.scr.2018.09.006openalex-extracted
Rapid and efficient differentiation of functional motor neurons from human iPSC for neural injury modelling
inferredcites →https://doi.org/10.1016/j.scr.2020.102035openalex-extracted
Haplobanking induced pluripotent stem cells for clinical use
inferredcites →https://doi.org/10.1016/j.stem.2012.03.002openalex-extracted
Background Mutations in Parental Cells Account for Most of the Genetic Heterogeneity of Induced Pluripotent Stem Cells
inferredcites →https://doi.org/10.1016/j.stem.2012.07.014openalex-extracted
Generating an iPSC Bank for HLA-Matched Tissue Transplantation Based on Known Donor and Recipient HLA Types
inferredcites →https://doi.org/10.1016/j.stem.2012.12.002openalex-extracted
Human iPSC-Derived Oligodendrocyte Progenitor Cells Can Myelinate and Rescue a Mouse Model of Congenital Hypomyelination
inferredcites →https://doi.org/10.1016/j.stem.2013.11.006openalex-extracted
Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging
inferredcites →https://doi.org/10.1016/j.stem.2014.02.004openalex-extracted
Modeling ALS with iPSCs Reveals that Mutant SOD1 Misregulates Neurofilament Balance in Motor Neurons
inferredcites →https://doi.org/10.1016/j.stem.2014.03.004openalex-extracted
Pathways Disrupted in Human ALS Motor Neurons Identified through Genetic Correction of Mutant SOD1
inferredcites →https://doi.org/10.1016/j.stem.2015.09.001openalex-extracted
Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects
inferredcites →https://doi.org/10.1016/j.stem.2016.11.005openalex-extracted
Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity
inferredcites →https://doi.org/10.1016/j.stem.2020.10.014openalex-extracted
CRISPR-Cas Tools and Their Application in Genetic Engineering of Human Stem Cells and Organoids
inferredcites →https://doi.org/10.1016/j.stem.2021.04.004openalex-extracted
Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients
inferredcites →https://doi.org/10.1016/j.stem.2023.05.015openalex-extracted
Advanced human iPSC-based preclinical model for Parkinson’s disease with optogenetic alpha-synuclein aggregation
inferredcites →https://doi.org/10.1016/j.stemcr.2013.09.006openalex-extracted
High Yields of Oligodendrocyte Lineage Cells from Human Embryonic Stem Cells at Physiological Oxygen Tensions for Evaluation of Translational Biology
inferredcites →https://doi.org/10.1016/j.stemcr.2017.06.018openalex-extracted
An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells
inferredcites →https://doi.org/10.1016/j.stemcr.2018.08.013openalex-extracted
Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study
inferredcites →https://doi.org/10.1016/j.stemcr.2020.03.023openalex-extracted
Impairment of Mitochondrial Calcium Buffering Links Mutations in C9ORF72 and TARDBP in iPS-Derived Motor Neurons from Patients with ALS/FTD
inferredcites →https://doi.org/10.1016/j.stemcr.2021.07.006openalex-extracted
NGN2 induces diverse neuron types from human pluripotency
inferredcites →https://doi.org/10.1016/j.tice.2023.102023openalex-extracted
Analysis of Aβ-induced neurotoxicity and microglial responses in simple two- and three-dimensional human iPSC-derived cortical culture systems
inferredcites →https://doi.org/10.1016/j.tins.2017.04.001openalex-extracted
The Role of Astrocyte Dysfunction in Parkinson’s Disease Pathogenesis
inferredcites →https://doi.org/10.1016/j.tins.2021.11.002openalex-extracted
The iPSC perspective on schizophrenia
inferredcites →https://doi.org/10.1016/j.tiv.2023.105668openalex-extracted
Evaluation of neurotoxicity for pesticide-related compounds in human iPS cell-derived neurons using microelectrode array
inferredcites →https://doi.org/10.1016/j.ymgme.2022.04.005openalex-extracted
Neurotoxicity of phenylalanine on human iPSC-derived cerebral organoids
inferredcites →https://doi.org/10.1021/acsbiomaterials.0c00067openalex-extracted
A Defined and Scalable Peptide-Based Platform for the Generation of Human Pluripotent Stem Cell-Derived Astrocytes
inferredcites →https://doi.org/10.1038/362059a0openalex-extracted
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
inferredcites →https://doi.org/10.1038/cr.2012.171openalex-extracted
Cell transplantation therapies for spinal cord injury focusing on induced pluripotent stem cells
inferredcites →https://doi.org/10.1038/nature.2014.15915openalex-extracted
Japanese woman is first recipient of next-generation stem cells
inferredcites →https://doi.org/10.1038/nature08797openalex-extracted
Direct conversion of fibroblasts to functional neurons by defined factors
inferredcites →https://doi.org/10.1038/nature09805openalex-extracted
Somatic coding mutations in human induced pluripotent stem cells
inferredcites →https://doi.org/10.1038/nature10284openalex-extracted
Direct generation of functional dopaminergic neurons from mouse and human fibroblasts
inferredcites →https://doi.org/10.1038/nature13716openalex-extracted
Synaptic dysregulation in a human iPS cell model of mental disorders
inferredcites →https://doi.org/10.1038/nature13800openalex-extracted
A three-dimensional human neural cell culture model of Alzheimer’s disease
inferredcites →https://doi.org/10.1038/nature22403openalex-extracted
Common genetic variation drives molecular heterogeneity in human iPSCs
inferredcites →https://doi.org/10.1038/ncomms1453openalex-extracted
Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus
inferredcites →https://doi.org/10.1038/ncomms1669openalex-extracted
Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells
inferredcites →https://doi.org/10.1038/ng.2802openalex-extracted
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
inferredcites →https://doi.org/10.1038/nm.4189openalex-extracted
Efficient derivation of microglia-like cells from human pluripotent stem cells
inferredcites →https://doi.org/10.1038/nm0216-116openalex-extracted
An eye to the future: Researchers debate best path for stem cell–derived therapies
inferredcites →https://doi.org/10.1038/nn.4534openalex-extracted
Differentiation of human and murine induced pluripotent stem cells to microglia-like cells
inferredcites →https://doi.org/10.1038/nnano.2017.133openalex-extracted
Electromagnetized gold nanoparticles mediate direct lineage reprogramming into induced dopamine neurons in vivo for Parkinson's disease therapy
inferredcites →https://doi.org/10.1038/nprot.2009.186openalex-extracted
Differentiation of human oligodendrocytes from pluripotent stem cells
inferredcites →https://doi.org/10.1038/nprot.2012.116openalex-extracted
Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks
inferredcites →https://doi.org/10.1038/nprot.2014.158openalex-extracted
Generation of cerebral organoids from human pluripotent stem cells
inferredcites →https://doi.org/10.1038/nprot.2015.075openalex-extracted
Generation and isolation of oligodendrocyte progenitor cells from human pluripotent stem cells
inferredcites →https://doi.org/10.1038/nrneurol.2012.263openalex-extracted
Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
inferredcites →https://doi.org/10.1038/s41380-018-0229-8openalex-extracted
Modeling amyloid beta and tau pathology in human cerebral organoids
inferredcites →https://doi.org/10.1038/s41380-021-01288-7openalex-extracted
iPSC toolbox for understanding and repairing disrupted brain circuits in autism
inferredcites →https://doi.org/10.1038/s41419-018-0737-0openalex-extracted
Human iPSC-based models highlight defective glial and neuronal differentiation from neural progenitor cells in metachromatic leukodystrophy
inferredcites →https://doi.org/10.1038/s41419-018-0990-2openalex-extracted
Establishment of stable iPS-derived human neural stem cell lines suitable for cell therapies
inferredcites →https://doi.org/10.1038/s41467-017-00911-yopenalex-extracted
HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients
inferredcites →https://doi.org/10.1038/s41467-017-00926-5openalex-extracted
MHC matching improves engraftment of iPSC-derived neurons in non-human primates
inferredcites →https://doi.org/10.1038/s41467-017-02299-1openalex-extracted
Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation
inferredcites →https://doi.org/10.1038/s41467-018-02866-0openalex-extracted
Single-cell full-length total RNA sequencing uncovers dynamics of recursive splicing and enhancer RNAs
inferredcites →https://doi.org/10.1038/s41467-019-12324-0openalex-extracted
MHC matching fails to prevent long-term rejection of iPSC-derived neurons in non-human primates
inferredcites →https://doi.org/10.1038/s41573-020-0079-3openalex-extracted
Organs-on-chips: into the next decade
inferredcites →https://doi.org/10.1038/s41577-019-0200-1openalex-extracted
Engineering universal cells that evade immune detection
inferredcites →https://doi.org/10.1038/s41580-020-0259-3openalex-extracted
Human organoids: model systems for human biology and medicine
inferredcites →https://doi.org/10.1038/s41586-021-03209-8openalex-extracted
Single-cell epigenomics reveals mechanisms of human cortical development
inferredcites →https://doi.org/10.1038/s41587-020-00763-wopenalex-extracted
Generation of human striatal organoids and cortico-striatal assembloids from human pluripotent stem cells
inferredcites →https://doi.org/10.1038/s41588-017-0005-8openalex-extracted
Molecular and functional variation in iPSC-derived sensory neurons
inferredcites →https://doi.org/10.1038/s41593-017-0047-3openalex-extracted
TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD
inferredcites →https://doi.org/10.1038/s41593-018-0316-9openalex-extracted
Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures
inferredcites →https://doi.org/10.1038/s41593-021-00802-yopenalex-extracted
Long-term maturation of human cortical organoids matches key early postnatal transitions
inferredcites →https://doi.org/10.1038/s41593-021-00906-5openalex-extracted
Identification of neural oscillations and epileptiform changes in human brain organoids
inferredcites →https://doi.org/10.1038/s41596-019-0248-1openalex-extracted
On-chip 3D neuromuscular model for drug screening and precision medicine in neuromuscular disease
inferredcites →https://doi.org/10.1038/s41598-022-23477-2openalex-extracted
Single-cell transcriptomics defines an improved, validated monoculture protocol for differentiation of human iPSC to microglia
inferredcites →https://doi.org/10.1038/s42003-021-02276-xopenalex-extracted
Resolving cell state in iPSC-derived human neural samples with multiplexed fluorescence imaging
inferredcites →https://doi.org/10.1056/nejmoa1211103openalex-extracted
Variant of TREM2 Associated with the Risk of Alzheimer's Disease
inferredcites →https://doi.org/10.1073/pnas.1108077108openalex-extracted
Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice
inferredcites →https://doi.org/10.1073/pnas.1300398110openalex-extracted
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy
inferredcites →https://doi.org/10.1073/pnas.1319061110openalex-extracted
Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells
inferredcites →https://doi.org/10.1073/pnas.1520760112openalex-extracted
Human cerebral organoids recapitulate gene expression programs of fetal neocortex development
inferredcites →https://doi.org/10.1073/pnas.1617259114openalex-extracted
Defective synaptic connectivity and axonal neuropathology in a human iPSC-based model of familial Parkinson’s disease
inferredcites →https://doi.org/10.1093/brain/awz419openalex-extracted
Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis
inferredcites →https://doi.org/10.1098/rsob.180177openalex-extracted
Opportunities and challenges for the use of induced pluripotent stem cells in modelling neurodegenerative disease
inferredcites →https://doi.org/10.1101/2020.06.29.174383openalex-extracted
Mapping genetic effects on cellular phenotypes with “cell villages”
inferredcites →https://doi.org/10.1101/gad.173922.111openalex-extracted
Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state
inferredcites →https://doi.org/10.1126/science.1154584openalex-extracted
TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
inferredcites →https://doi.org/10.1126/science.1158799openalex-extracted
Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons
inferredcites →https://doi.org/10.1126/science.1165942openalex-extracted
Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
inferredcites →https://doi.org/10.1126/science.1166066openalex-extracted
Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
inferredcites →https://doi.org/10.1126/science.1245296openalex-extracted
Identification and Rescue of α-Synuclein Toxicity in Parkinson Patient–Derived Neurons
inferredcites →https://doi.org/10.1126/science.aat6720openalex-extracted
Transcriptome and epigenome landscape of human cortical development modeled in organoids
inferredcites →https://doi.org/10.1126/scitranslmed.3007529openalex-extracted
Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion
inferredcites →https://doi.org/10.1126/scitranslmed.aaf3962openalex-extracted
The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis
inferredcites →https://doi.org/10.1126/scitranslmed.aai7866openalex-extracted
Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72 -associated amyotrophic lateral sclerosis
inferredcites →https://doi.org/10.1146/annurev-neuro-100720-034518openalex-extracted
Parkinson's Disease Genetics and Pathophysiology
inferredcites →https://doi.org/10.1177/2472555219857715openalex-extracted
Applying Deep Neural Network Analysis to High-Content Image-Based Assays
inferredcites →https://doi.org/10.1186/1472-6750-13-102openalex-extracted
Large-scale cell production of stem cells for clinical application using the automated cell processing machine
inferredcites →https://doi.org/10.1186/1756-6606-7-22openalex-extracted
iPS cell technologies: significance and applications to CNS regeneration and disease
inferredcites →https://doi.org/10.1186/1878-5085-4-23openalex-extracted
From integrative disease modeling to predictive, preventive, personalized and participatory (P4) medicine
inferredcites →https://doi.org/10.1186/s12929-019-0578-xopenalex-extracted
Human iPSC banking: barriers and opportunities
inferredcites →https://doi.org/10.1186/s13024-018-0297-xopenalex-extracted
Development and validation of a simplified method to generate human microglia from pluripotent stem cells
inferredcites →https://doi.org/10.1186/s13195-017-0317-zopenalex-extracted
Neurons derived from sporadic Alzheimer’s disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation
inferredcites →https://doi.org/10.1186/s13229-020-00383-wopenalex-extracted
Human stem cell-based models for studying autism spectrum disorder-related neuronal dysfunction
inferredcites →https://doi.org/10.1186/s13229-021-00417-xopenalex-extracted
Mind the translational gap: using iPS cell models to bridge from genetic discoveries to perturbed pathways and therapeutic targets
inferredcites →https://doi.org/10.1186/s13287-021-02217-9openalex-extracted
hiPSC-derived NSCs effectively promote the functional recovery of acute spinal cord injury in mice
inferredcites →https://doi.org/10.1242/dev.029447openalex-extracted
Human oligodendrocytes from embryonic stem cells: conserved SHH signaling networks and divergent FGF effects
inferredcites →https://doi.org/10.1371/journal.pone.0026159openalex-extracted
SNCA Triplication Parkinson's Patient's iPSC-derived DA Neurons Accumulate α-Synuclein and Are Susceptible to Oxidative Stress
inferredcites →https://doi.org/10.1371/journal.pone.0112413openalex-extracted
Higher Vulnerability and Stress Sensitivity of Neuronal Precursor Cells Carrying an Alpha-Synuclein Gene Triplication
inferredcites →https://doi.org/10.1371/journal.pone.0169506openalex-extracted
Functional Maturation of Human Stem Cell-Derived Neurons in Long-Term Cultures
inferredcites →https://doi.org/10.1523/jneurosci.0906-12.2013openalex-extracted
Accelerated High-Yield Generation of Limb-Innervating Motor Neurons from Human Stem Cells
inferredcites →https://doi.org/10.15252/emmm.201505439openalex-extracted
Aberrant epigenome in iPSC‐derived dopaminergic neurons from Parkinson's disease patients
inferredcites →https://doi.org/10.15252/msb.20145508openalex-extracted
Rapid neurogenesis through transcriptional activation in human stem cells
inferredcites →https://doi.org/10.21037/sci.2016.11.16openalex-extracted
The silver lining of induced pluripotent stem cell variation
inferredcites →https://doi.org/10.2217/rme-2016-0057openalex-extracted
Making it Personal: The Prospects for Autologous Pluripotent Stem Cell-Derived Therapies
inferredcites →https://doi.org/10.3233/jad-170830openalex-extracted
Overactive BRCA1 Affects Presenilin 1 in Induced Pluripotent Stem Cell-Derived Neurons in Alzheimer’s Disease
inferredcites →https://doi.org/10.3389/fimmu.2020.617860openalex-extracted
Alzheimer’s Risk Gene TREM2 Determines Functional Properties of New Type of Human iPSC-Derived Microglia
inferredcites →https://doi.org/10.3389/fncel.2015.00289openalex-extracted
Gene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration
inferredcites →https://doi.org/10.3389/fncel.2016.00290openalex-extracted
FUS Mislocalization and Vulnerability to DNA Damage in ALS Patients Derived hiPSCs and Aging Motoneurons
inferredcites →https://doi.org/10.3389/fncel.2020.00025openalex-extracted
Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model
inferredcites →https://doi.org/10.3389/fnmol.2017.00050openalex-extracted
Modeling Human Neurological and Neurodegenerative Diseases: From Induced Pluripotent Stem Cells to Neuronal Differentiation and Its Applications in Neurotrauma
inferredcites →https://doi.org/10.3389/fnmol.2017.00359openalex-extracted
Direct Reprogramming Rather than iPSC-Based Reprogramming Maintains Aging Hallmarks in Human Motor Neurons
inferredcites →https://doi.org/10.3389/fphar.2014.00235openalex-extracted
The inducible caspase-9 suicide gene system as a “safety switch” to limit on-target, off-tumor toxicities of chimeric antigen receptor T cells
inferredcites →https://doi.org/10.3390/cells11182803openalex-extracted
Cerebral Organoids as an Experimental Platform for Human Neurogenomics
inferredcites →https://doi.org/10.3791/56404-vopenalex-extracted
Modelling Zika Virus Infection of the Developing Human Brain In Vitro Using Stem Cell Derived Cerebral Organoids
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