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Loss of p53 Sensitizes Cells to Palmitic Acid-Induced Apoptosis by Reactive Oxygen Species Accumulation
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Annexin V-Affinity assay: A review on an apoptosis detection system based on phosphatidylserine exposure
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Identification of ROS Using Oxidized DCFDA and Flow-Cytometry
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P53 protein in proliferation, repair and apoptosis of cells
inferredcites →https://doi.org/10.1007/s11010-019-03572-1openalex-snapshot
Attenuating effect of silibinin on palmitic acid-induced apoptosis and mitochondrial dysfunction in pancreatic β-cells is mediated by estrogen receptor alpha
inferredcites →https://doi.org/10.1007/s11626-013-9646-9openalex-snapshot
Suppression of Grb2 expression improved hepatic steatosis, oxidative stress, and apoptosis induced by palmitic acid in vitro partly through insulin signaling alteration
inferredcites →https://doi.org/10.1007/s12020-012-9633-zopenalex-snapshot
Mitochondrial reactive oxygen species (ROS) inhibition ameliorates palmitate-induced INS-1 beta cell death
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[17] Structure and lipid binding properties of serum albumin
inferredcites →https://doi.org/10.1016/j.atherosclerosis.2017.06.002openalex-snapshot
Palmitate induces VSMC apoptosis via toll like receptor (TLR)4/ROS/p53 pathway
inferredcites →https://doi.org/10.1016/j.cell.2005.05.011openalex-snapshot
Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis
inferredcites →https://doi.org/10.1016/j.cell.2008.06.028openalex-snapshot
p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling
inferredcites →https://doi.org/10.1016/j.cell.2012.04.026openalex-snapshot
Tumor Suppression in the Absence of p53-Mediated Cell-Cycle Arrest, Apoptosis, and Senescence
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Oxyl radicals, redox-sensitive signalling cascades and antioxidants
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Abscisic acid synergizes with rosiglitazone to improve glucose tolerance and down-modulate macrophage accumulation in adipose tissue: Possible action of the cAMP/PKA/PPAR γ axis
inferredcites →https://doi.org/10.1016/j.jhep.2015.01.032openalex-snapshot
Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity
inferredcites →https://doi.org/10.1016/j.jhep.2017.11.014openalex-snapshot
Lipotoxicity and the gut-liver axis in NASH pathogenesis
inferredcites →https://doi.org/10.1016/j.molcel.2011.08.038openalex-snapshot
ROS-Mediated p53 Induction of Lpin1 Regulates Fatty Acid Oxidation in Response to Nutritional Stress
inferredcites →https://doi.org/10.1016/j.molmed.2017.02.001openalex-snapshot
p21: A Two-Faced Genome Guardian
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When the guardian sleeps: Reactivation of the p53 pathway in cancer
inferredcites →https://doi.org/10.1016/j.scr.2012.11.008openalex-snapshot
Palmitic acid increases apoptosis of neural stem cells via activating c-Jun N-terminal kinase
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Homeostatic functions of the p53 tumor suppressor: Regulation of energy metabolism and antioxidant defense
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Analysis of the mammalian gadd45 gene and its response to DNA damage.
inferredcites →https://doi.org/10.1016/s0022-2275(20)37421-6openalex-snapshot
Saturated but not mono-unsaturated fatty acids induce apoptotic cell death in neonatal rat ventricular myocytes
inferredcites →https://doi.org/10.1016/s0076-6879(00)22004-1openalex-snapshot
Detection of Apoptosis by Annexin V Labeling
inferredcites →https://doi.org/10.1023/a:1009616228304openalex-snapshot
Role of reactive oxygen species (ROS) in apoptosis induction
inferredcites →https://doi.org/10.1038/35003506openalex-snapshot
A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage
inferredcites →https://doi.org/10.1038/cdd.2012.102openalex-snapshot
The critical role of catalase in prooxidant and antioxidant function of p53
inferredcites →https://doi.org/10.1038/nm.2414openalex-snapshot
Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport
inferredcites →https://doi.org/10.1038/nm.4418openalex-snapshot
Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma
inferredcites →https://doi.org/10.1038/nm1320openalex-snapshot
The antioxidant function of the p53 tumor suppressor
inferredcites →https://doi.org/10.1038/nrm2395openalex-snapshot
Transcriptional control of human p53-regulated genes
inferredcites →https://doi.org/10.1042/bsr20190225openalex-snapshot
Oxidative and endoplasmic reticulum stresses are involved in palmitic acid-induced H9c2 cell apoptosis
inferredcites →https://doi.org/10.1073/pnas.93.21.11848openalex-snapshot
Reactive oxygen species are downstream mediators of p53-dependent apoptosis.
inferredcites →https://doi.org/10.1073/pnas.95.5.2498openalex-snapshot
Fatty acid-induced β cell apoptosis: A link between obesity and diabetes
inferredcites →https://doi.org/10.1074/jbc.m010286200openalex-snapshot
Palmitate-induced Apoptosis Can Occur through a Ceramide-independent Pathway
inferredcites →https://doi.org/10.1074/jbc.m103689200openalex-snapshot
Lack of Mitochondrial Anionic Phospholipids Causes an Inhibition of Translation of Protein Components of the Electron Transport Chain
inferredcites →https://doi.org/10.1101/cshperspect.a026104openalex-snapshot
The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression
inferredcites →https://doi.org/10.1152/ajpgi.00103.2019openalex-snapshot
High-fat diet promotes experimental colitis by inducing oxidative stress in the colon
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Regulation of reactive oxygen species by p53: implications for nitric oxide-mediated apoptosis
inferredcites →https://doi.org/10.1172/jci119700openalex-snapshot
Leptin- or troglitazone-induced lipopenia protects islets from interleukin 1beta cytotoxicity.
inferredcites →https://doi.org/10.1186/s40659-019-0253-4openalex-snapshot
Palmitic acid-induced lipotoxicity promotes a novel interplay between Akt-mTOR, IRS-1, and FFAR1 signaling in pancreatic β-cells
inferredcites →https://doi.org/10.1194/jlr.m004275openalex-snapshot
Distinct gene expression profiles characterize cellular responses to palmitate and oleate
inferredcites →https://doi.org/10.1210/en.2005-1494openalex-snapshot
Chronic Palmitate But Not Oleate Exposure Induces Endoplasmic Reticulum Stress, Which May Contribute to INS-1 Pancreatic β-Cell Apoptosis
inferredcites →https://doi.org/10.1371/journal.pone.0216939openalex-snapshot
Macronutrients influence yield and oil quality of hybrid maize (Zea mays L.)
inferredcites →https://doi.org/10.18632/aging.100738openalex-snapshot
High-fat diet induced obesity primes inflammation in adipose tissue prior to liver in C57BL/6j mice
inferredcites →https://doi.org/10.2337/diabetes.50.1.69openalex-snapshot
Distinct Effects of Saturated and Monounsaturated Fatty Acids on β-Cell Turnover and Function
inferredcites →https://doi.org/10.2337/diabetes.50.8.1771openalex-snapshot
Inverse Relationship Between Cytotoxicity of Free Fatty Acids in Pancreatic Islet Cells and Cellular Triglyceride Accumulation
inferredcites →https://doi.org/10.3109/07435800.2012.710883openalex-snapshot
P53 and Cellular Glucose Uptake
inferredcites →https://doi.org/10.3390/cancers10080255openalex-snapshot
Viability Assessment Following Anticancer Treatment Requires Single-Cell Visualization
inferredcites →https://doi.org/10.3390/ijms141122409openalex-snapshot
Ionizing Radiation-Induced Responses in Human Cells with Differing TP53 Status
inferredcites →https://doi.org/10.3390/ijms160511609openalex-snapshot
Spontaneous γH2AX Foci in Human Solid Tumor-Derived Cell Lines in Relation to p21WAF1 and WIP1 Expression
inferredcites →https://doi.org/10.3390/ijms18050928openalex-snapshot
Significance of Wild-Type p53 Signaling in Suppressing Apoptosis in Response to Chemical Genotoxic Agents: Impact on Chemotherapy Outcome
inferredcites →https://doi.org/10.3390/ijms18071460openalex-snapshot
Impact of Premature Senescence on Radiosensitivity Measured by High Throughput Cell-Based Assays
inferredcites →https://doi.org/10.3390/molecules200917339openalex-snapshot
Biological and Nutritional Properties of Palm Oil and Palmitic Acid: Effects on Health
inferredcites →https://doi.org/10.3390/plants8080293openalex-snapshot
Yield, Antioxidant Components, Oil Content, and Composition of Onion Seeds Are Influenced by Planting Time and Density
inferredcites →https://doi.org/10.4049/jimmunol.144.9.3326openalex-snapshot
Activation-induced cell death in T cell hybridomas is due to apoptosis. Morphologic aspects and DNA fragmentation.
inferredcites →https://doi.org/10.4161/nucl.32235openalex-snapshot
Nucleolar stress with and without p53
inferredcites →https://doi.org/10.5650/jos.ess19060openalex-snapshot
Enzyme-assisted Aqueous Extraction of Oil from Rice Germ and its Physicochemical Properties and Antioxidant Activity
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Linc00894 Inhibited Neuron Cellular Apoptosis Via Regulating Activating Transcription Factor 3 Expression
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Screening the Active Phytochemicals From Eclipta prostrata and Unraveling Their Molecular Insight Into Human Malignancies
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Targeting p53 for neuroinflammation: New therapeutic strategies in ischemic stroke
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Inhibition of PLA2G15 Alleviates Palmitic Acid‐Induced Lysosomal Membrane Permeabilization in Human Nucleus Pulposus Cells During Intervertebral Disc Degeneration
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Oxidative Stress: Signaling Pathways, Biological Functions, and Disease
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Tabersonine attenuates obesity‐induced renal injury via inhibiting NF‐κB ‐mediated inflammation
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Saturated fatty acids entrap PDX1 in stress granules and impede islet beta cell function
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Protective effects and mechanisms of Saikosaponin A against myocardial ischemia based on network pharmacology, molecular docking, and experimental validation
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Molecular characterization and functional analysis of apoptosis-inducing factor (AIF) in palmitic acid-induced apoptosis in Ctenopharyngodon idellus kidney (CIK) cells
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HNMT Promotes the Occurrence and Progression of Nasopharyngeal Carcinoma by Inhibiting the IFN/TXNIP/p53 Axis
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FABP4 Downregulated by FOS Alleviates Palmitic Acid-induced Endothelial Cell Dysfunction Via Inactivating ERK/STAT-1 Signaling Pathway
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Free fatty acid receptors type 2 and 4 mediate the anticancer effects of fatty acids in colorectal cancer - in vitro and in vivo studies
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From gut to brain: donepezil and nimodipine combination therapy improves cognitive deficits in Alzheimer's disease via gut microbiota and metabolites
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The role of endoplasmic reticulum stress on reducing recombinant protein production in mammalian cells
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ZYY-B-2, a novel ALK inhibitor, overcomes resistance to ceritinib by inhibiting P-gp function and induces apoptosis through mitochondrial pathway in ceritinib-resistant H2228 cells
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Palmitate-induced hepatic insulin resistance as an in vitro model for natural and synthetic drug screening: A scoping review of therapeutic candidates and mechanisms
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ARTS is essential for di-2-ethylhexyl phthalate (DEHP)-induced apoptosis of mouse Leydig cells
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Discovery of a cinnamyl piperidine derivative as new neddylation inhibitor for gastric cancer treatment
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ETNPPL impairs autophagy through regulation of the ARG2-ROS signaling axis, contributing to palmitic acid-induced hepatic insulin resistance
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Integrated metabolomics and flow cytometry assessment reveals immune-metabolic modulation of Crassostrea (=Magallana) gigas hemolymph under hypoxic and elevated temperature conditions
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LINC00894 inhibited neuron cellular apoptosis and regulated activating transcription factor 3 expression
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Allium willeanum Holmboe exerts anticancer activities on metastatic breast cancer cells MCF-7 and MDA-MB-231
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Integrated metabolomic and lipidomic analysis revealed the protective mechanisms of Erzhi Wan on senescent NRK cells through BRL cells
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p53 and TIGAR promote redox control to protect against metabolic dysfunction-associated steatohepatitis
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Dietary modulation of microRNAs in insulin resistance and type 2 diabetes
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To explore the regulatory role of Wnt/P53/Caspase3 signal in mouse ovarian development based on LFQ proteomics
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Adapalene-driven Mst1 modulation alleviates neuropathic pain by limiting Keap1-Mediated Nrf2 degradation in dorsal root ganglia
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Palmitic acid inhibits prostate cancer cell proliferation and metastasis by suppressing the PI3K/Akt pathway
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Effects of perfluorooctanoic acid on the nutritional quality of Mytilus edulis
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C1q/TNF-related protein-9 attenuates palmitic acid-induced endothelial cell senescence via increasing autophagy
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DRAM1 increases the secretion of PKM2-enriched EVs from hepatocytes to promote macrophage activation and disease progression in ALD
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Isogarcinol inhibits nasopharyngeal carcinoma growth through mitochondria-mediated autophagic cell death
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The mechanism of rh-endostatin-induced cardiotoxicity and its protection by dihydromyricetin[in vivo/in vitro, C57BL/6 mice, AC16 and hiPSC-CMs]
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Exosomes are involved in total body irradiation-induced intestinal injury in mice
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Deubiquitinase Mysm1 regulates neural stem cell proliferation and differentiation by controlling Id4 expression
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Lentinan suppresses the progression of neuroblastoma by inhibiting FOS-mediated transcription activation of VRK1 to stabilize p53 protein
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FADS2 confers SCD1 inhibition resistance to cancer cells by modulating the ER stress response
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Comprehensive insights into circular RNAs, miRNAs, and lncRNAs as biomarkers in retinoblastoma
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Excessive Apoptosis in Ulcerative Colitis: Crosstalk Between Apoptosis, ROS, ER Stress, and Intestinal Homeostasis
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Fasudil protects spiral ganglion neurons and hair cells against cisplatin-induced apoptosis by inhibiting reactive oxygen species accumulation and regulating the ROCK/PTEN/AKT signaling pathway
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cGAS‐STING mediates cytoplasmic mitochondrial‐DNA‐induced inflammatory signal transduction during accelerated senescence of pancreatic β‐cells induced by metabolic stress
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Palmitic acid‐induced ferroptosis via CD36 activates ER stress to break calcium‐iron balance in colon cancer cells
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PSMC2 is overexpressed in glioma and promotes proliferation and anti-apoptosis of glioma cells
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Finerenone attenuates myocardial apoptosis, metabolic disturbance and myocardial fibrosis in type 2 diabetes mellitus
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[Rosmarinic acid inhibits high glucose-induced cardiomyocyte hypertrophy by activating Parkin-mediated mitophagy].
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[Fucoxanthin induces prostate cancer PC-3 cell apoptosis by causing mitochondria dysfunction and oxidative stress].
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Navigating the crossroads of cell death interplay and intersections among ferroptosis, apoptosis and autophagy
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p53 and TIGAR promote redox control to protect against metabolic dysfunction-associated steatohepatitis
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Protective role of melatonin in ultraviolet radiation- induced oxidative stress in human skin photoaging
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DNA methylation-driven gene FAM3D promotes colorectal cancer growth via the ATF4-SESN2-mTORC1 pathway
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Anticancer and Apoptotic Activity in Cervical Adenocarcinoma HeLa using Crude Extract from Spike of Stomopneustes variolaris
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Palmitic Acid Inhibits Cell Proliferation and Tumor Growth of Endometrial Cancer In Vitro and In Vivo
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Effect of Oxidative Stress-Induced Autophagy on Proliferation and Apoptosis of hMSCs
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Effect of oxidative stress-induced autophagy on proliferation and apoptosis of hMSCs
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Ailanthone Increases Cisplatin-induced Apoptosis and Autophagy in Cisplatin Resistance Non-small Cell Lung Cancer Cells through the PI3K/AKT/mTOR Pathway
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Study of the Effect of Palmitic Acid on the Expression of Myostatin mRNA and its Cytotoxic Properties in the Culture of Myoblast Cells and the Possibility of Exogenous Regulation
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Bioinformatics-based Identification of Ferroptosis-related Genes and their Diagnostic Value in Gestational Diabetes Mellitus
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Palmitic acid hinders extracellular traps of neutrophil from postpartum dairy cow in vitro
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miR-344-5p Modulates Cholesterol-Induced β-Cell Apoptosis and Dysfunction Through Regulating Caveolin-1 Expression
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Dysregulated sphingolipid metabolism and autophagy in granulosa cells of women with endometriosis
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The role of protein S-acylation in vascular injury associated with metabolic disorders
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Cannabidiol treatment improves metabolic profile and decreases hypothalamic inflammation caused by maternal obesity
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Dysregulated Phosphorylation of p53, Autophagy and Stemness Attributes the Mutant p53 Harboring Colon Cancer Cells Impaired Sensitivity to Oxaliplatin
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A novel oxidative stress-related genes signature associated with clinical prognosis and immunotherapy responses in clear cell renal cell carcinoma
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Molecular mechanism of palmitic acid and its derivatives in tumor progression
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Acetylated Dendrobium huoshanense polysaccharide: a novel inducer of apoptosis in colon cancer cells via Fas–FasL pathway activation and metabolic reprogramming
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Natural products target programmed cell death signaling mechanisms to treat colorectal cancer
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Resveratrol targeting MDM2/P53/PUMA axis to inhibit colonocyte apoptosis in DSS-induced ulcerative colitis mice
inferred← citeshttps://doi.org/10.3389/fphar.2025.1592046openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/ani14233421openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/antiox11102006openalex-snapshot
Histone Methyltransferase MLL1 Mediates Oxidative Stress and Apoptosis upon Deoxynivalenol Exposure in the Intestinal Porcine Epithelial Cells
inferred← citeshttps://doi.org/10.3390/antiox13070831openalex-snapshot
Canagliflozin Inhibits Palmitic Acid-Induced Vascular Cell Aging In Vitro through ROS/ERK and Ferroptosis Pathways
inferred← citeshttps://doi.org/10.3390/biom14050601openalex-snapshot
Palmitic Acid Exerts Anti-Tumorigenic Activities by Modulating Cellular Stress and Lipid Droplet Formation in Endometrial Cancer
inferred← citeshttps://doi.org/10.3390/cells13211781openalex-snapshot
Therapeutic Potential of Stearoyl-CoA Desaturase1 (SCD1) in Modulating the Effects of Fatty Acids on Osteoporosis
inferred← citeshttps://doi.org/10.3390/cells15090805openalex-snapshot
Paraclostridium tenue Exhibits Antitumor Activity Through Generating Antitumor Metabolites and Modulating Gut Microbiota
inferred← citeshttps://doi.org/10.3390/genes15050577openalex-snapshot
Comprehensive Bioinformatic Investigation of TP53 Dysregulation in Diverse Cancer Landscapes
inferred← citeshttps://doi.org/10.3390/ijms241210201openalex-snapshot
Different Roles of Apoptosis and Autophagy in the Development of Human Colorectal Cancer
inferred← citeshttps://doi.org/10.3390/ijms26020788openalex-snapshot
Protection Strategies Against Palmitic Acid-Induced Lipotoxicity in Metabolic Syndrome and Related Diseases
inferred← citeshttps://doi.org/10.3390/md22100465openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/molecules30050997openalex-snapshot
Chemical Analysis and Antioxidant Activities of Resin Fractions from Pistacia lentiscus L. var. Chia in Neuroblastoma SH-SY5Y Cells
inferred← citeshttps://doi.org/10.3390/pr11051306openalex-snapshot
In Vitro Cytotoxicity Assessment of Abutilon pannosum Chloroform Fraction and Its Phytoconstituents Analysis
inferred← citeshttps://doi.org/10.37268/mjphm/vol.21/no.1/art.789openalex-snapshot
ENZYME-LINKED IMMUNOSORBENT ASSAY DETECTION FOR MALIGNANCY USING ANTI-P53 ANTIBODIES
inferred← citeshttps://doi.org/10.3892/etm.2022.11386openalex-snapshot
CTRP9 overexpression attenuates palmitic acid‑induced inflammation, apoptosis and impaired migration in HTR8/SVneo cells through AMPK/SREBP1c signaling
inferred← citeshttps://doi.org/10.3892/mmr.2023.13121openalex-snapshot
IGF‑1 inhibits palmitic acid‑induced mitochondrial apoptosis in macrophages
inferred← citeshttps://doi.org/10.54254/2753-8818/2024.la18824openalex-snapshot
Current knowledge of apoptosis and targeting apoptotic pathways for cancer therapy
inferred← citeshttps://doi.org/10.6084/m9.figshare.19359522openalex-snapshot
Additional file 1 of PSMC2 is overexpressed in glioma and promotes proliferation and anti-apoptosis of glioma cells
inferred← citeshttps://doi.org/10.64898/2026.09.02.748892openalex-snapshot
Cholesterol and p53 promote senescence and systemic fibrosis in metabolic dysfunction-associated steatohepatitis
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