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Role of the Transcription Factor FOSL1 in Organ Development and Tumorigenesis

https://doi.org/10.3390/ijms23031521
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/cncr.26652openalex-snapshot
The molecular role of Fra‐1 and its prognostic significance in human esophageal squamous cell carcinoma
inferredcites →https://doi.org/10.1002/hep.24175openalex-snapshot
Transcription factor Fra-1 induces cholangitis and liver fibrosis
inferredcites →https://doi.org/10.1002/jbmr.5650080710openalex-snapshot
Stable murine chondrogenic cell lines derived from c-fos-induced cartilage tumors
inferredcites →https://doi.org/10.1002/pros.20113openalex-snapshot
Co‐operative functions between nuclear factors NFκB and CCAT/enhancer‐binding protein‐β (C/EBP‐β) regulate the IL‐6 promoter in autocrine human prostate cancer cells
inferredcites →https://doi.org/10.1006/jmcc.1993.1127openalex-snapshot
Expression of c-fos and Related Genes in the Rat Heart in Response to Norepinephrine
inferredcites →https://doi.org/10.1007/978-3-642-54490-3_15openalex-snapshot
Trametinib
inferredcites →https://doi.org/10.1007/bf01076476openalex-snapshot
Regulation of transcription factor mRNA accumulation during 3T3-L1 preadipocyte differentiation by antagonists of adipogenesis
inferredcites →https://doi.org/10.1007/s00280-013-2121-1openalex-snapshot
PI3K and MEK inhibitor combinations: examining the evidence in selected tumor types
inferredcites →https://doi.org/10.1007/s003920170040openalex-snapshot
Transcriptional regulation of matrix gla protein
inferredcites →https://doi.org/10.1007/s10517-011-1208-0openalex-snapshot
Effects of Expression of Transcriptional Factor AP-1 FOSL1 Gene on Psoriatic Process
inferredcites →https://doi.org/10.1007/s11033-014-3027-7openalex-snapshot
Matrix Gla protein (MGP) promoter polymorphic variants and its serum level in stenosis of coronary artery
inferredcites →https://doi.org/10.1016/0169-328x(93)90113-4openalex-snapshot
Brain transcription factor expression: effects of acute and chronic amphetamine and injection stress
inferredcites →https://doi.org/10.1016/j.bbcan.2019.04.003openalex-snapshot
The AP-1 transcriptional complex: Local switch or remote command?
inferredcites →https://doi.org/10.1016/j.bbrc.2010.04.067openalex-snapshot
Role of AP-1 and RE-1 binding sites in matrix metalloproteinase-2 transcriptional regulation in skeletal muscle atrophy
inferredcites →https://doi.org/10.1016/j.ccr.2012.10.009openalex-snapshot
Relief of Profound Feedback Inhibition of Mitogenic Signaling by RAF Inhibitors Attenuates Their Activity in BRAFV600E Melanomas
inferredcites →https://doi.org/10.1016/j.ccr.2013.08.005openalex-snapshot
Protein Kinase C α Is a Central Signaling Node and Therapeutic Target for Breast Cancer Stem Cells
inferredcites →https://doi.org/10.1016/j.cell.2009.07.031openalex-snapshot
Histone Crosstalk between H3S10ph and H4K16ac Generates a Histone Code that Mediates Transcription Elongation
inferredcites →https://doi.org/10.1016/j.cmet.2013.11.018openalex-snapshot
Regulation of Steatohepatitis and PPARγ Signaling by Distinct AP-1 Dimers
inferredcites →https://doi.org/10.1016/j.drudis.2021.02.006openalex-snapshot
Cancer vaccines: An unkept promise?
inferredcites →https://doi.org/10.1016/j.gene.2012.09.112openalex-snapshot
A polymorphism of matrix Gla protein gene is associated with kidney stone in the Chinese Han population
inferredcites →https://doi.org/10.1016/j.molcel.2009.08.002openalex-snapshot
RSK Is a Principal Effector of the RAS-ERK Pathway for Eliciting a Coordinate Promotile/Invasive Gene Program and Phenotype in Epithelial Cells
inferredcites →https://doi.org/10.1016/j.scr.2017.12.004openalex-snapshot
Fosl1 overexpression directly activates trophoblast-specific gene expression programs in embryonic stem cells
inferredcites →https://doi.org/10.1016/j.tcb.2018.12.001openalex-snapshot
EMT Transition States during Tumor Progression and Metastasis
inferredcites →https://doi.org/10.1016/s0021-9258(19)50091-6openalex-snapshot
Inhibition of myogenesis by okadaic acid, an inhibitor of protein phosphatases, 1 and 2A, correlates with the induction of AP1.
inferredcites →https://doi.org/10.1038/79676openalex-snapshot
Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1
inferredcites →https://doi.org/10.1038/bjc.2014.476openalex-snapshot
Beyond BRAF: where next for melanoma therapy?
inferredcites →https://doi.org/10.1038/cdd.2014.157openalex-snapshot
Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression
inferredcites →https://doi.org/10.1038/embor.2008.74openalex-snapshot
A reciprocal repression between ZEB1 and members of the miR‐200 family promotes EMT and invasion in cancer cells
inferredcites →https://doi.org/10.1038/ja.2007.87openalex-snapshot
Aberrant Expression of Fra-1 in Estrogen Receptor-negative Breast Cancers and Suppression of their Propagation In Vivo by Ascochlorin, an Antibiotic that Inhibits Cellular Activator Protein-1 Activity
inferredcites →https://doi.org/10.1038/msb.2012.32openalex-snapshot
Reverse engineering a hierarchical regulatory network downstream of oncogenic KRAS
inferredcites →https://doi.org/10.1038/ncb0502-e131openalex-snapshot
AP-1 as a regulator of cell life and death
inferredcites →https://doi.org/10.1038/ncb1722openalex-snapshot
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
inferredcites →https://doi.org/10.1038/nrc1209openalex-snapshot
AP-1: a double-edged sword in tumorigenesis
inferredcites →https://doi.org/10.1038/nrc2559openalex-snapshot
Targeting cancer with small molecule kinase inhibitors
inferredcites →https://doi.org/10.1038/nrc3265openalex-snapshot
To differentiate or not — routes towards metastasis
inferredcites →https://doi.org/10.1038/onc.2011.101openalex-snapshot
Interstitial lung disease induced by gefitinib and Toll-like receptor ligands is mediated by Fra-1
inferredcites →https://doi.org/10.1038/onc.2011.336openalex-snapshot
Fra-1 controls motility of bladder cancer cells via transcriptional upregulation of the receptor tyrosine kinase AXL
inferredcites →https://doi.org/10.1038/onc.2011.375openalex-snapshot
A 19S proteasomal subunit cooperates with an ERK MAPK-regulated degron to regulate accumulation of Fra-1 in tumour cells
inferredcites →https://doi.org/10.1038/onc.2011.659openalex-snapshot
The PKCθ pathway participates in the aberrant accumulation of Fra-1 protein in invasive ER-negative breast cancer cells
inferredcites →https://doi.org/10.1038/onc.2012.432openalex-snapshot
MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1
inferredcites →https://doi.org/10.1038/onc.2013.278openalex-snapshot
Prolactin cooperates with loss of p53 to promote claudin-low mammary carcinomas
inferredcites →https://doi.org/10.1038/onc.2014.374openalex-snapshot
FRA-1 as a driver of tumour heterogeneity: a nexus between oncogenes and embryonic signalling pathways in cancer
inferredcites →https://doi.org/10.1038/s41388-020-1306-4openalex-snapshot
The nuclear oncoprotein Fra-1: a transcription factor knocking on therapeutic applications’ door
inferredcites →https://doi.org/10.1038/s41467-021-24137-1openalex-snapshot
Transcriptional super-enhancers control cancer stemness and metastasis genes in squamous cell carcinoma
inferredcites →https://doi.org/10.1038/sj.emboj.7600282openalex-snapshot
The Fos‐related antigen Fra‐1 is an activator of bone matrix formation
inferredcites →https://doi.org/10.1038/sj.jid.5701049openalex-snapshot
Synergistic Activation of Human Involucrin Gene Expression by Fra-1 and p300—Evidence for the Presence of a Multiprotein Complex
inferredcites →https://doi.org/10.1038/sj.onc.1201046openalex-snapshot
Cross-family interaction between the bHLHZip USF and bZip Fra1 proteins results in down-regulation of AP1 activity
inferredcites →https://doi.org/10.1038/sj.onc.1207585openalex-snapshot
Transcriptional basis of KRAS oncogene-mediated cellular transformation in ovarian epithelial cells
inferredcites →https://doi.org/10.1042/bj20020707openalex-snapshot
A functional activating protein 1 (AP-1) site regulates matrix metalloproteinase 2 (MMP-2) transcription by cardiac cells through interactions with JunB-Fra1 and JunB-FosB heterodimers
inferredcites →https://doi.org/10.1042/bst0360858openalex-snapshot
Fos family protein degradation by the proteasome
inferredcites →https://doi.org/10.1046/j.1365-2443.2003.00631.xopenalex-snapshot
Regulation of c‐Fos and Fra‐1 by the MEK5‐ERK5 pathway
inferredcites →https://doi.org/10.1046/j.1432-1033.2003.03821.xopenalex-snapshot
Fra‐1 targets the AP‐1 site/2G single nucleotide polymorphism (ETS site) in the MMP‐1 promoter
inferredcites →https://doi.org/10.1073/pnas.1222085110openalex-snapshot
Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis
inferredcites →https://doi.org/10.1073/pnas.90.5.1657openalex-snapshot
A selective transcriptional induction system for mammalian cells based on Gal4-estrogen receptor fusion proteins.
inferredcites →https://doi.org/10.1074/jbc.273.49.32957openalex-snapshot
A Synergistic Interaction of Transcription Factors AP2 and YB-1 Regulates Gelatinase A Enhancer-dependent Transcription
inferredcites →https://doi.org/10.1074/jbc.274.45.32091openalex-snapshot
The Nuclear Factor-κB Engages CBP/p300 and Histone Acetyltransferase Activity for Transcriptional Activation of the Interleukin-6 Gene Promoter
inferredcites →https://doi.org/10.1074/jbc.c111.296707openalex-snapshot
Molecular Characterization of the MicroRNA-138-Fos-like Antigen 1 (FOSL1) Regulatory Module in Squamous Cell Carcinoma
inferredcites →https://doi.org/10.1074/jbc.c800074200openalex-snapshot
The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional Repressors ZEB1 and ZEB2
inferredcites →https://doi.org/10.1074/jbc.m104909200openalex-snapshot
A Polymorphism of the Human Matrix γ-Carboxyglutamic Acid Protein Promoter Alters Binding of an Activating Protein-1 Complex and Is Associated with Altered Transcription and Serum Levels
inferredcites →https://doi.org/10.1074/jbc.m111.290874openalex-snapshot
Binding Site Specificity and Factor Redundancy in Activator Protein-1-driven Human Papillomavirus Chromatin-dependent Transcription
inferredcites →https://doi.org/10.1074/jbc.m200445200openalex-snapshot
Combinatorial Interactions of p53, Activating Protein-2, and YB-1 with a Single Enhancer Element Regulate Gelatinase A Expression in Neoplastic Cells
inferredcites →https://doi.org/10.1074/jbc.m303505200openalex-snapshot
Multiple cis-Elements Mediate the Transcriptional Activation of Human fra-1 by 12-O-Tetradecanoylphorbol-13-acetate in Bronchial Epithelial Cells
inferredcites →https://doi.org/10.1080/01616412.2020.1748323openalex-snapshot
Low expression ofFOSL1is associated with favorable prognosis and sensitivity to radiation/pharmaceutical therapy in lower grade glioma
inferredcites →https://doi.org/10.1083/jcb.201103097openalex-snapshot
A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial–mesenchymal transition
inferredcites →https://doi.org/10.1089/ars.2007.1968openalex-snapshot
Opposite Expression of the Antioxidant Heme Oxygenase-1 in Primary Cells and Tumor Cells: Regulation by Interaction of USF-2 and Fra-1
inferredcites →https://doi.org/10.1093/carcin/bgr304openalex-snapshot
MicroRNA-34a inhibits migration and invasion of colon cancer cells via targeting to Fra-1
inferredcites →https://doi.org/10.1093/emboj/cdg158openalex-snapshot
Determinants of proteasome recognition of ornithine decarboxylase, a ubiquitin‐independent substrate
inferredcites →https://doi.org/10.1101/gad.1640608openalex-snapshot
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
inferredcites →https://doi.org/10.1111/j.1365-2559.2011.03785.xopenalex-snapshot
Role of Fos‐related antigen 1 in the progression and prognosis of ductal breast carcinoma
inferredcites →https://doi.org/10.1111/j.1600-0714.2009.00869.xopenalex-snapshot
Fos-related activator-1 is overexpressed in oral squamous cell carcinoma and associated with tumor lymph node metastasis
inferredcites →https://doi.org/10.1126/science.1228522openalex-snapshot
Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition
inferredcites →https://doi.org/10.1126/scisignal.2003884openalex-snapshot
Epigenetic Activation of AP1 Promotes Squamous Cell Carcinoma Metastasis
inferredcites →https://doi.org/10.1128/mcb.01054-12openalex-snapshot
FOSL1 Controls the Assembly of Endothelial Cells into Capillary Tubes by Direct Repression of αv and β3 Integrin Transcription
inferredcites →https://doi.org/10.1128/mcb.01776-06openalex-snapshot
Ubiquitin-Independent Proteasomal Degradation of Fra-1 Is Antagonized by Erk1/2 Pathway-Mediated Phosphorylation of a Unique C-Terminal Destabilizer
inferredcites →https://doi.org/10.1128/mcb.13.3.1911openalex-snapshot
The NFAT-1 DNA Binding Complex in Activated T Cells Contains Fra-1 and JunB
inferredcites →https://doi.org/10.1128/mcb.24.1.144-153.2004openalex-snapshot
A Network of Immediate Early Gene Products Propagates Subtle Differences in Mitogen-Activated Protein Kinase Signal Amplitude and Duration
inferredcites →https://doi.org/10.1128/mcb.24.11.4696-4709.2004openalex-snapshot
An Extracellular Signal-Regulated Kinase 1- and 2-Dependent Program of Chromatin Trafficking of c-Fos and Fra-1 Is Required for Cyclin D1 Expression during Cell Cycle Reentry
inferredcites →https://doi.org/10.1134/s102279541001014xopenalex-snapshot
Expression of the FOSL1 gene in psoriasis and atherosclerosis
inferredcites →https://doi.org/10.1152/ajpregu.00161.2002openalex-snapshot
Multiple transcription factors regulating the IL-6 gene are activated by cAMP in cultured Caco-2 cells
inferredcites →https://doi.org/10.1152/physiolgenomics.00173.2006openalex-snapshot
Genome-wide analysis of SPAK/OSR1 binding motifs
inferredcites →https://doi.org/10.1158/0008-5472.can-08-1942openalex-snapshot
A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition
inferredcites →https://doi.org/10.1158/0008-5472.can-13-3396openalex-snapshot
Genome-wide Profiling of AP-1–Regulated Transcription Provides Insights into the Invasiveness of Triple-Negative Breast Cancer
inferredcites →https://doi.org/10.1158/1078-0432.ccr-07-1990openalex-snapshot
Interleukin-13 Receptor α2, EphA2, and Fos-Related Antigen 1 as Molecular Denominators of High-Grade Astrocytomas and Specific Targets for Combinatorial Therapy
inferredcites →https://doi.org/10.1158/1541-7786.mcr-06-0263openalex-snapshot
Phosphatidylinositol-3-OH Kinase or RAS Pathway Mutations in Human Breast Cancer Cell Lines
inferredcites →https://doi.org/10.1161/circgenetics.113.000003openalex-snapshot
Common Genetic Variants of MGP Are Associated With Calcification on the Arterial Wall but Not With Calcification Present in the Atherosclerotic Plaques
inferredcites →https://doi.org/10.1165/rcmb.2011-0169ocopenalex-snapshot
Genetic Disruption of Fra-1 Decreases Susceptibility to Endotoxin-Induced Acute Lung Injury and Mortality in Mice
inferredcites →https://doi.org/10.1165/rcmb.2017-0164ocopenalex-snapshot
FOSL1 Promotes Kras-induced Lung Cancer through Amphiregulin and Cell Survival Gene Regulation
inferredcites →https://doi.org/10.1172/jci63608openalex-snapshot
ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression
inferredcites →https://doi.org/10.1186/1471-2407-13-441openalex-snapshot
Expression of activator protein-1 (AP-1) family members in breast cancer
inferredcites →https://doi.org/10.1186/1471-2407-6-298openalex-snapshot
An association of a simultaneous nuclear and cytoplasmic localization of Fra-1 with breast malignancy
inferredcites →https://doi.org/10.1186/1471-2407-7-17openalex-snapshot
FRA-1 protein overexpression is a feature of hyperplastic and neoplastic breast disorders
inferredcites →https://doi.org/10.1242/dev.127.22.4937openalex-snapshot
Placental vascularisation requires the AP-1 component Fra1
inferredcites →https://doi.org/10.1242/jcs.00812openalex-snapshot
Elevated ERK-MAP kinase activity protects the FOS family member FRA-1 against proteasomal degradation in colon carcinoma cells
inferredcites →https://doi.org/10.1242/jcs.079855openalex-snapshot
Elevated Fra-1 expression causes severe lipodystrophy
inferredcites →https://doi.org/10.1359/jbmr.090603openalex-snapshot
Fra-1/AP-1 Impairs Inflammatory Responses and Chondrogenesis in Fracture Healing
inferredcites →https://doi.org/10.1371/journal.pone.0053211openalex-snapshot
Old Players with a Newly Defined Function: Fra-1 and c-Fos Support Growth of Human Malignant Breast Tumors by Activating Membrane Biogenesis at the Cytoplasm
inferredcites →https://doi.org/10.1371/journal.pone.0059057openalex-snapshot
XB130, a New Adaptor Protein, Regulates Expression of Tumor Suppressive MicroRNAs in Cancer Cells
inferredcites →https://doi.org/10.1371/journal.pone.0088950openalex-snapshot
Widespread FRA1-Dependent Control of Mesenchymal Transdifferentiation Programs in Colorectal Cancer Cells
inferredcites →https://doi.org/10.1385/1-59259-046-2:121openalex-snapshot
The Matrix Metalloproteinase (MMP) and Tissue Inhibitor of Metalloproteinase (TIMP) Genes: Transcriptional and Posttranscriptional Regulation, Signal Transduction and Cell-Type-Specific Expression
inferredcites →https://doi.org/10.1590/1678-4685-gmb-2017-0267openalex-snapshot
Association of FOSL1 copy number alteration and triple negative breast tumors
inferredcites →https://doi.org/10.1590/s1516-31802013000100016openalex-snapshot
Expression of claudin, paxillin and FRA-1 in non-nodular breast lesions in association with microcalcifications
inferredcites →https://doi.org/10.1615/critrevoncog.v18.i1-2.70openalex-snapshot
The Tumor Microenvironment: A Target for Combination therapy of Breast Cancer
inferredcites →https://doi.org/10.18632/oncotarget.199openalex-snapshot
Epithelial mesenchymal transition and tumor budding in aggressive colorectal cancer: Tumor budding as oncotarget
inferredcites →https://doi.org/10.3389/fcell.2021.728325openalex-snapshot
Mechanistic Insights Delineating the Role of Cholesterol in Epithelial Mesenchymal Transition and Drug Resistance in Cancer
inferredcites →https://doi.org/10.3390/cells10123435openalex-snapshot
Aspects of the Epigenetic Regulation of EMT Related to Cancer Metastasis
inferredcites →https://doi.org/10.3390/cells9020291openalex-snapshot
Tumor Infiltrating Neutrophils Are Enriched in Basal-Type Urothelial Bladder Cancer
inferredcites →https://doi.org/10.3390/molecules21070965openalex-snapshot
Targeting Epithelial–Mesenchymal Transition (EMT) to Overcome Drug Resistance in Cancer
inferredcites →https://doi.org/10.3748/wjg.v21.i34.9863openalex-snapshot
Circulating microRNAs and long non-coding RNAs in gastric cancer diagnosis: An update and review
inferredcites →https://doi.org/10.3899/jrheum.100985openalex-snapshot
Matrix Gla Protein Polymorphism, But Not Concentrations, Is Associated with Radiographic Hand Osteoarthritis
inferredcites →https://doi.org/10.3904/kjim.2001.16.2.93openalex-snapshot
Fra-1 Expression in Malignant and Benign Thyroid Tumor
inferredcites →https://doi.org/10.4049/jimmunol.1502364openalex-snapshot
Expression Profiling of Macrophages Reveals Multiple Populations with Distinct Biological Roles in an Immunocompetent Orthotopic Model of Lung Cancer
inferredcites →https://doi.org/10.4161/cbt.11.2.13953openalex-snapshot
Fos-related antigen 1 (Fra-1) pairing with and transactivation of JunB in GBM cells
inferredcites →https://doi.org/10.4161/cbt.3.10.1141openalex-snapshot
NF-kappaB activates IL-6 expression through cooperation with c-Jun and IL6-AP1 site, But is independent of its IL6-NFkappaB regulatory site in autocrine human multiple myeloma cells
inferredcites →https://doi.org/10.4161/cc.10.24.18552openalex-snapshot
miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions
inferredcites →https://doi.org/10.7554/elife.64846openalex-snapshot
NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Recurrent FOSL1 rearrangements in desmoplastic fibroblastoma
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Exosome-transmitted FOSL1 from cancer-associated fibroblasts drives colorectal cancer stemness and chemo-resistance through transcriptionally activating ITGB4
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FOSL1 mediates collagen synthesis and myofibroblast transformation in aortic fibroblasts under Ang II-induced aortic dissection conditions
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FOSL1: The core regulatory hub of tumor-neural interactions and its clinical translational prospects
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Single-cell multiomics gene regulatory landscape reveals impaired spermatogonial stem cells and macrophage-driven inflammaging during testicular aging
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Self-healing and pH-responsive bioactive hydrogel dressing loaded with Ramulus Mori-derived exosome-like nanovesicles accelerates diabetic wound healing
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Ezrin, a novel marker of ependymal cells, can be used to demonstrate their proliferation regulation after spinal cord injury in mice
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HLA-DQB1-mediated B cell-epithelial crosstalk drives EBV-associated inflammation in Hunner-type interstitial cystitis
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Roles, underlying mechanisms and clinical significances of LINC01503 in human cancers
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2024.174023openalex-snapshot
The influence of digestive tract protein on cytotoxicity of polyvinyl chloride microplastics
inferred← citeshttps://doi.org/10.1016/j.stem.2024.11.013openalex-snapshot
Spatiotemporal single-cell roadmap of human skin wound healing
inferred← citeshttps://doi.org/10.1016/j.ydbio.2025.10.014openalex-snapshot
Molecular basis of variations in facial soft tissues: insights from cichlid fishes
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5c01335openalex-snapshot
PARP7: an Emerging Therapeutic Target-Insights into Biological Functions and Advances in Small-Molecule Inhibitor Development
inferred← citeshttps://doi.org/10.1038/s41392-026-02799-xopenalex-snapshot
Multiomic profiling of responses to clinical and novel bisphosphonates reveals extraskeletal effects on ageing related signatures
inferred← citeshttps://doi.org/10.1038/s41418-024-01308-3openalex-snapshot
m6A demethylation of FOSL1 mRNA protects hepatoma cells against necrosis under glucose deprivation
inferred← citeshttps://doi.org/10.1038/s41419-024-06692-9openalex-snapshot
Mature neurons from iPSCs unveil neurodegeneration-related pathways in mucopolysaccharidosis type II: GSK-3β inhibition for therapeutic potential
inferred← citeshttps://doi.org/10.1038/s41419-025-08086-xopenalex-snapshot
Comprehensive map of the regulatory network triggered by MET exon 14 skipping reveals important involvement of the RAS-ERK signaling pathway
inferred← citeshttps://doi.org/10.1038/s41467-023-39448-8openalex-snapshot
UBAP2 plays a role in bone homeostasis through the regulation of osteoblastogenesis and osteoclastogenesis
inferred← citeshttps://doi.org/10.1038/s41598-024-53272-0openalex-snapshot
A novel anoikis-related gene signature identifies LYPD1 as a novel therapy target for bladder cancer
inferred← citeshttps://doi.org/10.1038/s41598-024-64726-wopenalex-snapshot
RUNX1 regulates MCM2/CDC20 to promote COAD progression modified by deubiquitination of USP31
inferred← citeshttps://doi.org/10.1038/s41598-025-07982-8openalex-snapshot
Mitochondria-related gene-based molecular subtypes of lung adenocarcinoma and their prognostic implications
inferred← citeshttps://doi.org/10.1038/s41598-025-99128-zopenalex-snapshot
FOSL1 promotes keratinocyte migration and wound repair by modulating the IL17 signaling pathway
inferred← citeshttps://doi.org/10.1073/pnas.2309047120openalex-snapshot
PARP7-mediated ADP-ribosylation of FRA1 promotes cancer cell growth by repressing IRF1- and IRF3-dependent apoptosis
inferred← citeshttps://doi.org/10.1080/14728222.2022.2137020openalex-snapshot
The molecular mechanisms and targeting strategies of transcription factors in cholangiocarcinoma
inferred← citeshttps://doi.org/10.1093/cvr/cvag189openalex-snapshot
Beyond the vessel wall: single-cell dissection of epicardial fat–myocardial crosstalk in coronary artery disease
inferred← citeshttps://doi.org/10.1093/rb/rbaf110openalex-snapshot
Study on the role and mechanism of magnesium-calcium-mineralized collagen composite scaffolds in the adjuvant treatment of cervical cancer
inferred← citeshttps://doi.org/10.1097/md.0000000000045473openalex-snapshot
Identification of differential expressed genes common to rheumatoid arthritis and osteoporosis based on GEO database
inferred← citeshttps://doi.org/10.1101/2024.08.30.609923openalex-snapshot
Spatiotemporal Single-Cell Roadmap of Human Skin Wound Healing
inferred← citeshttps://doi.org/10.1101/2024.09.05.611379openalex-snapshot
A consensus single-cell transcriptomic atlas of dermal fibroblast heterogeneity
inferred← citeshttps://doi.org/10.1101/2024.11.21.624322openalex-snapshot
Stage-specific phenotypic and transcriptional alterations in keratinocytes exposed to acute and chronic blue light
inferred← citeshttps://doi.org/10.1101/2025.03.25.645228openalex-snapshot
Bisphosphonates Trigger Anti-Ageing Effects Across Multiple Cell Types and Protect Against Senescence
inferred← citeshttps://doi.org/10.1101/2025.10.13.682225openalex-snapshot
Mechanosensitive Stanniocalcin-1 Attenuates Pulmonary Arterial Hypertension by Suppressing Smooth Muscle Cell Proliferation
inferred← citeshttps://doi.org/10.1101/533323openalex-snapshot
Multi-omic analysis of CIC’s functional networks reveals novel interaction partners and a potential role in mitotic fidelity
inferred← citeshttps://doi.org/10.1111/acel.70705openalex-snapshot
3D Culture Reverses Limbal Niche Cell Replicative Aging via FOSL1 Upregulation
inferred← citeshttps://doi.org/10.1111/php.14095openalex-snapshot
Stage‐specific phenotypic and transcriptional alterations in HaCaT keratinocytes exposed to acute and chronic blue light
inferred← citeshttps://doi.org/10.1134/s0022093023050083openalex-snapshot
Chronic Dysregulation of Glutamatergic Transmission in the Hippocampus of Krushinsky–Molodkina Rats Induced by Repeated Epileptiform Seizures
inferred← citeshttps://doi.org/10.1152/jn.00351.2024openalex-snapshot
Isorhamnetin ameliorates dopaminergic neuronal damage via targeting FOSL1 to activate AKT/mTOR in 6-OHDA-induced SH-SY5Y cells
inferred← citeshttps://doi.org/10.1158/1535-7163.mct-25-0483openalex-snapshot
Resistance to the KRASG12D Inhibitor MRTX1133 Is Associated with Increased Sensitivity to BET Inhibition
inferred← citeshttps://doi.org/10.1158/2159-8290.cd-25-0237openalex-snapshot
Epigenetic and Transcriptional Programs Define Osteosarcoma Subtypes and Establish Targetable Vulnerabilities
inferred← citeshttps://doi.org/10.1161/circresaha.125.327869openalex-snapshot
Mechanosensitive Stanniocalcin-1 Suppresses Smooth Muscle Cell Proliferation and Attenuates Experimental Pulmonary Hypertension
inferred← citeshttps://doi.org/10.1186/s12864-025-11874-6openalex-snapshot
Effects of dietary protein levels on genes related to subcutaneous fat deposition and lipid metabolism in Tibetan sheep
inferred← citeshttps://doi.org/10.1186/s12967-024-06014-9openalex-snapshot
FOSL1 transcriptionally dictates the Warburg effect and enhances chemoresistance in triple-negative breast cancer
inferred← citeshttps://doi.org/10.1186/s12967-025-06304-wopenalex-snapshot
FOSL1 drives the malignant progression of pancreatic cancer cells by regulating cell stemness, metastasis and multidrug efflux system
inferred← citeshttps://doi.org/10.1186/s12967-025-07380-8openalex-snapshot
Dynamic remodelling of epithelial plasticity in colorectal cancer from single-cell and spatially resolved perspectives
inferred← citeshttps://doi.org/10.1186/s13072-024-00542-wopenalex-snapshot
Chromatin profiling and state predictions reveal insights into epigenetic regulation during early porcine development
inferred← citeshttps://doi.org/10.1186/s13072-024-00559-1openalex-snapshot
FOSL1 is a key regulator of a super-enhancer driving TCOF1 expression in triple-negative breast cancer
inferred← citeshttps://doi.org/10.1186/s13148-024-01632-yopenalex-snapshot
Molecular map of disulfidptosis-related genes in lung adenocarcinoma: the perspective toward immune microenvironment and prognosis
inferred← citeshttps://doi.org/10.1186/s13287-024-04083-7openalex-snapshot
FAM96B negatively regulates FOSL1 to modulate the osteogenic differentiation and regeneration of periodontal ligament stem cells via ferroptosis
inferred← citeshttps://doi.org/10.1186/s40164-026-00763-7openalex-snapshot
Systematic and precise interventions for KRAS-mutant cancers
inferred← citeshttps://doi.org/10.1371/journal.pgen.1011319openalex-snapshot
Trajectory-centric framework TrajAtlas reveals multi-scale differentiation heterogeneity among cells, genes, and gene modules in osteogenesis
inferred← citeshttps://doi.org/10.1371/journal.pone.0298802openalex-snapshot
Digital spatial profiling of segmental outflow regions in trabecular meshwork reveals a role for ADAM15
inferred← citeshttps://doi.org/10.14740/wjon1608openalex-snapshot
FOS-Like Antigen 1 Expression Was Associated With Survival of Hepatocellular Carcinoma Patients
inferred← citeshttps://doi.org/10.1667/rade-22-00216.1openalex-snapshot
Genomic Loss and Epigenetic Silencing of the FOSL1 Tumor Suppressor Gene in Radiation-induced Neoplastic Transformation of Human CGL1 Cells Alters the Tumorigenic Phenotype In Vitro and In Vivo
inferred← citeshttps://doi.org/10.20944/preprints202312.1378.v1openalex-snapshot
FOSL1’s Diverse Roles in Glioma/Glioma Stem Cells and Tu-morigenesis: A Comprehensive Review
inferred← citeshttps://doi.org/10.21203/rs.3.rs-2057247/v1openalex-snapshot
Identification and Analysis of Hub Transcriptional Factors Related to Acetaminophen-Induced Liver Injury
inferred← citeshttps://doi.org/10.21203/rs.3.rs-2367007/v1openalex-snapshot
Novel diagnostic, therapeutic, and prognostic biomarkers for nonalcoholic steatohepatitis-derived hepatocellular carcinoma: Capable to overcome the heterogeneity-specific barrier
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3300466/v1openalex-snapshot
Identification and Analysis of Hub Transcriptional Factors in vitro hepatocyte model of Acetaminophen- Induced Liver Injury
inferred← citeshttps://doi.org/10.21518/ms2023-290openalex-snapshot
Alterations in IL-17 expression in pediatric patients with psoriatic arthritis
inferred← citeshttps://doi.org/10.2174/0115665240343441241231102305openalex-snapshot
Using the AP1 Transcription Factor FOSL1 to Assess the Exacerbation of Psoriasis
inferred← citeshttps://doi.org/10.2217/epi-2023-0046openalex-snapshot
Transcription Factors: A Potential Therapeutic Target in Head and Neck Squamous Cell Carcinoma
inferred← citeshttps://doi.org/10.31083/fbl26898openalex-snapshot
Transcription Factor FOSL1 Promotes Cisplatin Resistance in Non-Small Cell Lung Cancer Cells by Modulating the Wnt3a/β-Catenin Signaling through Upregulation of PLIN3 Expression
inferred← citeshttps://doi.org/10.31857/s0044452923050029openalex-snapshot
CHRONIC DYSREGULATION OF GLUTAMATERGIC TRANSMISSION IN THE HIPPOCAMPUS OF KRUSHINSKY–MOLODKINA RATS INDUCED BY REPEATED EPILEPTIFORM SEIZURES
inferred← citeshttps://doi.org/10.3389/fcell.2023.1183328openalex-snapshot
Therapeutic targeting of anoikis resistance in cutaneous melanoma metastasis
inferred← citeshttps://doi.org/10.3389/fcell.2025.1659986openalex-snapshot
FRA1 (FOSL1) suppresses neoplastic transformation and modulates radiation responses via transcriptional control of mitogenic and stress-responsive networks
inferred← citeshttps://doi.org/10.3389/fgene.2022.953580openalex-snapshot
MiR-33a targets FOSL1 and EN2 as a clinical prognostic marker for sarcopenia by glioma
inferred← citeshttps://doi.org/10.3389/fimmu.2022.954744openalex-snapshot
The Fra-1: Novel role in regulating extensive immune cell states and affecting inflammatory diseases
inferred← citeshttps://doi.org/10.3389/fonc.2022.900108openalex-snapshot
FOSL1 promotes tumor growth and invasion in ameloblastoma
inferred← citeshttps://doi.org/10.3389/fphar.2025.1617508openalex-snapshot
Melatonin: a natural guardian in cancer treatment
inferred← citeshttps://doi.org/10.3389/fpsyt.2025.1629900openalex-snapshot
Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction
inferred← citeshttps://doi.org/10.3390/biom16050647openalex-snapshot
The Role of FOSL1 in Inflammatory Bowel Disease (IBD) Pathogenesis and IBD-Associated Tumorigenesis
inferred← citeshttps://doi.org/10.3390/cancers15102805openalex-snapshot
Multi-Omic Analysis of CIC’s Functional Networks Reveals Novel Interaction Partners and a Potential Role in Mitotic Fidelity
inferred← citeshttps://doi.org/10.3390/cells12020330openalex-snapshot
Synovial Fluid Derived from Human Knee Osteoarthritis Increases the Viability of Human Adipose-Derived Stem Cells through Upregulation of FOSL1
inferred← citeshttps://doi.org/10.3390/cells12192344openalex-snapshot
Overexpression of FRA1 (FOSL1) Leads to Global Transcriptional Perturbations, Reduced Cellular Adhesion and Altered Cell Cycle Progression
inferred← citeshttps://doi.org/10.3390/cells14070534openalex-snapshot
PPAR-γ in Melanoma and Immune Cells: Insights into Disease Pathogenesis and Therapeutic Implications
inferred← citeshttps://doi.org/10.3390/curroncol31090360openalex-snapshot
A Comprehensive Review of Protein Biomarkers for Invasive Lung Cancer
inferred← citeshttps://doi.org/10.3390/genes16010075openalex-snapshot
The X-Linked Tumor Suppressor TSPX Regulates Genes Involved in the EGFR Signaling Pathway and Cell Viability to Suppress Lung Adenocarcinoma
inferred← citeshttps://doi.org/10.3390/ijms23179708openalex-snapshot
The Role of Transcription Factor PPAR-γ in the Pathogenesis of Psoriasis, Skin Cells, and Immune Cells
inferred← citeshttps://doi.org/10.3390/ijms24087222openalex-snapshot
Advances in Molecular Research of Oncogenes
inferred← citeshttps://doi.org/10.3390/ijms24098307openalex-snapshot
FRA-1 as a Regulator of EMT and Metastasis in Breast Cancer
inferred← citeshttps://doi.org/10.3390/ijms25105362openalex-snapshot
FOSL1’s Oncogene Roles in Glioma/Glioma Stem Cells and Tumorigenesis: A Comprehensive Review
inferred← citeshttps://doi.org/10.3390/ijms26020434openalex-snapshot
Transcriptomic Insights into Post-Spawning Death and Muscle Atrophy in Ayu (Plecoglossus altivelis)
inferred← citeshttps://doi.org/10.6084/m9.figshare.26679641openalex-snapshot
Additional file 1 of Molecular map of disulfidptosis-related genes in lung adenocarcinoma: the perspective toward immune microenvironment and prognosis
inferred← citeshttps://doi.org/10.6084/m9.figshare.26679644openalex-snapshot
Additional file 2 of Molecular map of disulfidptosis-related genes in lung adenocarcinoma: the perspective toward immune microenvironment and prognosis
inferred← citeshttps://doi.org/10.6084/m9.figshare.26723313openalex-snapshot
Additional file 1 of Chromatin profiling and state predictions reveal insights into epigenetic regulation during early porcine development
inferred← citeshttps://doi.org/10.6084/m9.figshare.26723316openalex-snapshot
Additional file 2 of Chromatin profiling and state predictions reveal insights into epigenetic regulation during early porcine development
inferred← citeshttps://doi.org/10.6084/m9.figshare.26723319openalex-snapshot
Additional file 3 of Chromatin profiling and state predictions reveal insights into epigenetic regulation during early porcine development
inferred← citeshttps://doi.org/10.6084/m9.figshare.26723322openalex-snapshot
Additional file 4 of Chromatin profiling and state predictions reveal insights into epigenetic regulation during early porcine development
inferred← citeshttps://doi.org/10.6084/m9.figshare.26723325openalex-snapshot
Additional file 5 of Chromatin profiling and state predictions reveal insights into epigenetic regulation during early porcine development
inferred← citeshttps://doi.org/10.6084/m9.figshare.26723328openalex-snapshot
Additional file 6 of Chromatin profiling and state predictions reveal insights into epigenetic regulation during early porcine development
inferred← citeshttps://doi.org/10.6084/m9.figshare.26723331openalex-snapshot
Additional file 7 of Chromatin profiling and state predictions reveal insights into epigenetic regulation during early porcine development
inferred← citeshttps://doi.org/10.7554/elife.86827openalex-snapshot
A MSTNDel73C mutation with FGF5 knockout sheep by CRISPR/Cas9 promotes skeletal muscle myofiber hyperplasia
inferred← citeshttps://doi.org/10.7554/elife.86827.1openalex-snapshot
A MSTNDel273C mutation with FGF5 knockout sheep by CRISPR/Cas9 promotes skeletal muscle myofiber hyperplasia via MEK-ERK-FOSL1 axis
inferred← citeshttps://doi.org/10.7554/elife.86827.2openalex-snapshot
A MSTNDel273C mutation with FGF5 knockout sheep by CRISPR/Cas9 promotes skeletal muscle myofiber hyperplasia
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