On the public citation graph

Glutathione-Mediated Conjugation of Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation

https://doi.org/10.3390/molecules27165252

0 signed · 280 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.

Claim with ORCID

Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.

See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/9781118180778openalex-snapshot

ADME‐Enabling Technologies in Drug Design and Development

inferredcites →https://doi.org/10.1002/chin.199951281openalex-snapshot

ChemInform Abstract: An Overview of Cyclophosphamide Development and Clinical Applications

inferredcites →https://doi.org/10.1002/med.1016openalex-snapshot

Role of drug metabolism in drug discovery and development

inferredcites →https://doi.org/10.1002/med.21364openalex-snapshot

Mitoxantrone, More than Just Another Topoisomerase II Poison

inferredcites →https://doi.org/10.1006/abio.1999.4258openalex-snapshot

Analysis of Glutathione and Glutathione Disulfide in Whole Cells and Mitochondria by Postcolumn Derivatization High-Performance Liquid Chromatography with ortho-Phthalaldehyde

inferredcites →https://doi.org/10.1007/978-1-4613-1601-5_11openalex-snapshot

Glutathione S—transferase and drug resistance

inferredcites →https://doi.org/10.1007/978-3-7643-8336-7openalex-snapshot

Molecular, Clinical and Environmental Toxicology

inferredcites →https://doi.org/10.1007/978-3-7643-8336-7_3openalex-snapshot

The role of biotransformation and bioactivation in toxicity

inferredcites →https://doi.org/10.1007/bf00194530openalex-snapshot

Antitumor diarylsulfonylureas: novel agents with unfulfilled promise

inferredcites →https://doi.org/10.1007/bf00873919openalex-snapshot

Phase II study of sulofenur (LY 186641)

inferredcites →https://doi.org/10.1007/s00204-013-1040-6openalex-snapshot

The metabolic profile of mitoxantrone and its relation with mitoxantrone-induced cardiotoxicity

inferredcites →https://doi.org/10.1007/s00204-019-02589-1openalex-snapshot

Novel insights into the mechanism of cyclophosphamide-induced bladder toxicity: chloroacetaldehyde’s contribution to urothelial dysfunction in vitro

inferredcites →https://doi.org/10.1007/s00280-002-0453-3openalex-snapshot

Cytochrome P450 isozymes 3A4 and 2B6 are involved in the in vitro human metabolism of thiotepa to TEPA

inferredcites →https://doi.org/10.1007/s00280-016-3152-1openalex-snapshot

The effect of cyclophosphamide on the immune system: implications for clinical cancer therapy

inferredcites →https://doi.org/10.1007/s00726-005-0243-4openalex-snapshot

Cysteine S-conjugate β-lyases

inferredcites →https://doi.org/10.1007/s10593-015-1695-4openalex-snapshot

Nucleophilic substitution of nitro group in nitrotriazolotriazines as a model of potential interaction with cysteine-containing proteins

inferredcites →https://doi.org/10.1007/s10637-010-9407-5openalex-snapshot

Cellular resistance to a nitric oxide releasing glutathione S-transferase P-activated prodrug, PABA/NO

inferredcites →https://doi.org/10.1007/s10863-016-9670-zopenalex-snapshot

The anticancer agent 3-bromopyruvate: a simple but powerful molecule taken from the lab to the bedside

inferredcites →https://doi.org/10.1007/s11224-012-0020-4openalex-snapshot

DFT study on Thiotepa and Tepa interactions with their DNA receptor

inferredcites →https://doi.org/10.1007/s13318-014-0176-yopenalex-snapshot

Metabolism of cisplatin in the organs of Rattus norvegicus: role of Glutathione S-transferase P1

inferredcites →https://doi.org/10.1007/s40620-017-0392-zopenalex-snapshot

Cisplatin nephrotoxicity: a review of the literature

inferredcites →https://doi.org/10.1016/0006-2952(84)90598-7openalex-snapshot

The effects of buthionine sulphoximine (BSO) on glutathione depletion and xenobiotic biotransformation

inferredcites →https://doi.org/10.1016/0006-2952(90)90465-wopenalex-snapshot

Inhibition of rat and human glutathione S-transferase isoenzymes by ethacrynic acid and its glutathione conjugate

inferredcites →https://doi.org/10.1016/0024-3205(74)90206-9openalex-snapshot

Glutathione; Metabolism and function via the γ-glutamyl cycle

inferredcites →https://doi.org/10.1016/0041-008x(90)90100-9openalex-snapshot

Glutathione conjugate mediated toxicities*1

inferredcites →https://doi.org/10.1016/0045-2068(82)90039-6openalex-snapshot

The carbonyl reactivity of 3-bromopyruvate and related compounds

inferredcites →https://doi.org/10.1016/0304-3835(95)03942-popenalex-snapshot

Studies on the mechanism of sulofenur and LY295501 toxicity: effect on the regulation of cytosolic calcium in relation to cytotoxicity in normal and tumorigenic rat kidney cell lines

inferredcites →https://doi.org/10.1016/0305-7372(95)90023-3openalex-snapshot

High-dose chemotherapy regimens for solid tumors

inferredcites →https://doi.org/10.1016/1074-5521(95)90120-5openalex-snapshot

Mitomycin C: small, fast and deadly (but very selective)

inferredcites →https://doi.org/10.1016/b978-0-12-420117-0.00006-2openalex-snapshot

Glutathione Transferases in the Bioactivation of Azathioprine

inferredcites →https://doi.org/10.1016/b978-0-12-812838-1.50010-4openalex-snapshot

Nucleophilic Substitution and Elimination Reactions

inferredcites →https://doi.org/10.1016/b978-0-444-62649-3.00006-5openalex-snapshot

Anticancer Drugs That Interact with the DNA Minor Groove

inferredcites →https://doi.org/10.1016/j.ab.2005.05.036openalex-snapshot

Evaluation of the effect of oxygen exposure on human liver microsomal metabolism of mitomycin C in the presence of glutathioneusing liquid chromatography–quadrupole time of flight mass spectrometry

inferredcites →https://doi.org/10.1016/j.abb.2015.08.005openalex-snapshot

The busulfan metabolite EdAG irreversibly glutathionylates glutaredoxins

inferredcites →https://doi.org/10.1016/j.bbagen.2012.09.018openalex-snapshot

Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes

inferredcites →https://doi.org/10.1016/j.bcp.2010.06.002openalex-snapshot

Comparative metabolism of cyclophosphamide and ifosfamide in the mouse using UPLC–ESI-QTOFMS-based metabolomics

inferredcites →https://doi.org/10.1016/j.cell.2012.03.042openalex-snapshot

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

inferredcites →https://doi.org/10.1016/j.cell.2013.12.010openalex-snapshot

Regulation of Ferroptotic Cancer Cell Death by GPX4

inferredcites →https://doi.org/10.1016/j.celrep.2019.01.043openalex-snapshot

A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity

inferredcites →https://doi.org/10.1016/j.ctrv.2006.09.006openalex-snapshot

Molecular mechanisms of resistance and toxicity associated with platinating agents

inferredcites →https://doi.org/10.1016/j.ejmech.2018.04.001openalex-snapshot

Therapeutic journery of nitrogen mustard as alkylating anticancer agents: Historic to future perspectives

inferredcites →https://doi.org/10.1016/j.ejmech.2020.112599openalex-snapshot

Design, synthesis and high antitumor potential of new unsymmetrical bisacridine derivatives towards human solid tumors, specifically pancreatic cancers and their unique ability to stabilize DNA G-quadruplexes

inferredcites →https://doi.org/10.1016/j.ejphar.2014.07.025openalex-snapshot

Cisplatin in cancer therapy: Molecular mechanisms of action

inferredcites →https://doi.org/10.1016/j.eururo.2018.11.033openalex-snapshot

Cabozantinib Versus Mitoxantrone-prednisone in Symptomatic Metastatic Castration-resistant Prostate Cancer: A Randomized Phase 3 Trial with a Primary Pain Endpoint

inferredcites →https://doi.org/10.1016/j.freeradbiomed.2019.05.035openalex-snapshot

The role of thiols in antioxidant systems

inferredcites →https://doi.org/10.1016/j.jchromb.2018.05.011openalex-snapshot

Bioanalysis of ibrutinib, and its dihydrodiol- and glutathione cycle metabolites by liquid chromatography-tandem mass spectrometry

inferredcites →https://doi.org/10.1016/j.jmb.2007.11.034openalex-snapshot

Structural Determinants of Glutathione Transferases with Azathioprine Activity Identified by DNA Shuffling of Alpha Class Members

inferredcites →https://doi.org/10.1016/j.jmb.2008.04.066openalex-snapshot

The Anti-cancer Drug Chlorambucil as a Substrate for the Human Polymorphic Enzyme Glutathione Transferase P1-1: Kinetic Properties and Crystallographic Characterisation of Allelic Variants

inferredcites →https://doi.org/10.1016/j.jpha.2021.03.014openalex-snapshot

Novel insights into conjugation of antitumor-active unsymmetrical bisacridine C-2028 with glutathione: Characteristics of non-enzymatic and glutathione S-transferase-mediated reactions

inferredcites →https://doi.org/10.1016/j.mam.2008.05.005openalex-snapshot

Regulation of glutathione synthesis

inferredcites →https://doi.org/10.1016/j.mam.2008.08.006openalex-snapshot

Glutathione: Overview of its protective roles, measurement, and biosynthesis

inferredcites →https://doi.org/10.1016/j.mehy.2017.01.014openalex-snapshot

The promising anticancer drug 3-bromopyruvate is metabolized through glutathione conjugation which affects chemoresistance and clinical practice: An evidence-based view

inferredcites →https://doi.org/10.1016/j.pharep.2015.11.007openalex-snapshot

Anticancer agent 3-bromopyruvic acid forms a conjugate with glutathione

inferredcites →https://doi.org/10.1016/s0009-2797(00)00214-3openalex-snapshot

Glutathione conjugation as a bioactivation reaction

inferredcites →https://doi.org/10.1016/s0009-2797(97)00146-4openalex-snapshot

Glutathione: an overview of biosynthesis and modulation

inferredcites →https://doi.org/10.1016/s0021-9258(19)77815-6openalex-snapshot

Glutathione metabolism and its selective modification.

inferredcites →https://doi.org/10.1016/s0021-9258(20)80702-9openalex-snapshot

Glutathione-associated cis-diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione-platinum complex and its biological significance.

inferredcites →https://doi.org/10.1016/s0024-3205(03)00173-5openalex-snapshot

Conjugation of chlorambucil with GSH by GST purified from human colon adenocarcinoma cells and its inhibition by plant polyphenols

inferredcites →https://doi.org/10.1016/s0065-230x(08)60848-9openalex-snapshot

The Role of Glutathione and Glutathione S-Transferases in the Metabolism of Chemical Carcinogens and Other Electrophilic Agents

inferredcites →https://doi.org/10.1016/s0090-9556(25)07199-5openalex-snapshot

Glutathione conjugation with phosphoramide mustard and cyclophosphamide. A mechanistic study using tandem mass spectrometry.

inferredcites →https://doi.org/10.1016/s0090-9556(25)07498-7openalex-snapshot

Busulfan conjugation by glutathione S-transferases alpha, mu, and pi.

inferredcites →https://doi.org/10.1016/s0140-6736(03)14110-4openalex-snapshot

Long-term effect of a watch and wait policy versus immediate systemic treatment for asymptomatic advanced-stage non-Hodgkin lymphoma: a randomised controlled trial

inferredcites →https://doi.org/10.1016/s0168-8278(01)00196-9openalex-snapshot

Mechanism of azathioprine-induced injury to hepatocytes: roles of glutathione depletion and mitochondrial injury

inferredcites →https://doi.org/10.1016/s0378-4347(01)00279-1openalex-snapshot

Cyclophosphamide and related anticancer drugs

inferredcites →https://doi.org/10.1016/s0753-3322(03)00043-xopenalex-snapshot

The importance of glutathione in human disease

inferredcites →https://doi.org/10.1016/s0891-5849(99)00176-8openalex-snapshot

Biologic and pharmacologic regulation of mammalian glutathione synthesis

inferredcites →https://doi.org/10.1016/s0891-5849(99)00177-xopenalex-snapshot

Glutathione and its role in cellular functions

inferredcites →https://doi.org/10.1021/acs.chemrestox.5b00430openalex-snapshot

Covalent DNA–Protein Cross-Linking by Phosphoramide Mustard and Nornitrogen Mustard in Human Cells

inferredcites →https://doi.org/10.1021/bi00273a015openalex-snapshot

Stereoselectivity of isozyme C of glutathione S-transferase toward arene and azaarene oxides

inferredcites →https://doi.org/10.1021/cr9001066openalex-snapshot

Platinum Drug Distribution in Cancer Cells and Tumors

inferredcites →https://doi.org/10.1021/jm050700kopenalex-snapshot

PABA/NO as an Anticancer Lead: Analogue Synthesis, Structure Revision, Solution Chemistry, Reactivity toward Glutathione, and in Vitro Activity

inferredcites →https://doi.org/10.1021/jm2006222openalex-snapshot

Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor Tyrosine Kinase

inferredcites →https://doi.org/10.1021/jo0016529openalex-snapshot

The Secondary Amine/Nitric Oxide Complex Ion R2N[N(O)NO]- as Nucleophile and Leaving Group in SNAr Reactions

inferredcites →https://doi.org/10.1021/tx00029a012openalex-snapshot

Comparison of metabolism and toxicity to the structure of the anticancer agent sulofenur and related sulfonylureas

inferredcites →https://doi.org/10.1021/tx00039a017openalex-snapshot

Conjugation of Glutathione and Other Thiols with Bioreductively Activated Mitomycin C. Effect of Thiols on the Reductive Activation Rate

inferredcites →https://doi.org/10.1021/tx00049a012openalex-snapshot

Glutathione Conjugation of the Cytostatic Drug Ifosfamide and the Role of Human Glutathione S-Transferases

inferredcites →https://doi.org/10.1021/tx0155698openalex-snapshot

Glutathione-Dependent Metabolism of the Antitumor Agent Sulofenur. Evidence for the Formation of p-Chlorophenyl Isocyanate as a Reactive Intermediate

inferredcites →https://doi.org/10.1021/tx100172xopenalex-snapshot

Prediction of Michael-Type Acceptor Reactivity toward Glutathione

inferredcites →https://doi.org/10.1021/tx700212uopenalex-snapshot

Verification of the Structural Alerts for Michael Acceptors

inferredcites →https://doi.org/10.1021/tx950143copenalex-snapshot

Glutathione Conjugation of Alkylating Cytostatic Drugs with a Nitrogen Mustard Group and the Role of Glutathione S-Transferases

inferredcites →https://doi.org/10.1021/tx960072xopenalex-snapshot

Structure, Catalytic Mechanism, and Evolution of the Glutathione Transferases

inferredcites →https://doi.org/10.1021/tx960092zopenalex-snapshot

Bioactivation of 6,7-Dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843) to Reactive Intermediates That Bind Covalently to Macromolecules and Produce Genotoxicity1

inferredcites →https://doi.org/10.1023/a:1008060720608openalex-snapshot

Mechanisms of resistance to alkylating agents

inferredcites →https://doi.org/10.1038/cdd.2009.37openalex-snapshot

Glutathione disulfide induces neural cell death via a 12-lipoxygenase pathway

inferredcites →https://doi.org/10.1038/nrd2468openalex-snapshot

Prodrugs: design and clinical applications

inferredcites →https://doi.org/10.1038/s41389-017-0025-3openalex-snapshot

Glutathione transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases

inferredcites →https://doi.org/10.1038/s41557-018-0079-7openalex-snapshot

Concerted nucleophilic aromatic substitutions

inferredcites →https://doi.org/10.1038/sj.bmt.1702377openalex-snapshot

The effect of busulphan on the pharmacokinetics of cyclophosphamide and its 4-hydroxy metabolite: time interval influence on therapeutic efficacy and therapy-related toxicity

inferredcites →https://doi.org/10.1038/sj.onc.1206940openalex-snapshot

The role of glutathione-S-transferase in anti-cancer drug resistance

inferredcites →https://doi.org/10.1038/srep08092openalex-snapshot

Unbalanced Activation of Glutathione Metabolic Pathways Suggests Potential Involvement in Plant Defense against the Gall Midge Mayetiola destructor in Wheat

inferredcites →https://doi.org/10.1039/b907567dopenalex-snapshot

Inhibition of transcription by platinum antitumor compounds

inferredcites →https://doi.org/10.1039/c2sc20627gopenalex-snapshot

Interactions of anticancer Pt compounds with proteins: an overlooked topic in medicinal inorganic chemistry?

inferredcites →https://doi.org/10.1039/c9ra09115gopenalex-snapshot

Phase I metabolic profiling and unexpected reactive metabolites in human liver microsome incubations of X-376 using LC-MS/MS: bioactivation pathway elucidation and in silico toxicity studies of its metabolites

inferredcites →https://doi.org/10.1039/c9ra10871hopenalex-snapshot

Identification and characterization of in silico , in vivo , in vitro , and reactive metabolites of infigratinib using LC-ITMS: bioactivation pathway elucidation and in silico toxicity studies of its metabolites

inferredcites →https://doi.org/10.1042/bsr20190880openalex-snapshot

Hexokinase II inhibition by 3-bromopyruvate sensitizes myeloid leukemic cells K-562 to anti-leukemic drug, daunorubicin

inferredcites →https://doi.org/10.1053/ctrv.2000.0170openalex-snapshot

Chemistry, pharmacology and pharmacokinetics of N,N′,N′′ -triethylenethiophosphoramide (ThioTEPA)

inferredcites →https://doi.org/10.1055/s-2000-11123openalex-snapshot

Glutathione Adducts of Helenalin and 11α,13-Dihydrohelenalin Acetate Inhibit Glutathione S-Transferase from Horse Liver1

inferredcites →https://doi.org/10.1074/jbc.m116.748129openalex-snapshot

Helenalin Acetate, a Natural Sesquiterpene Lactone with Anti-inflammatory and Anti-cancer Activity, Disrupts the Cooperation of CCAAT Box/Enhancer-binding Protein β (C/EBPβ) and Co-activator p300

inferredcites →https://doi.org/10.1080/10715760802317663openalex-snapshot

Glutathione and apoptosis

inferredcites →https://doi.org/10.1080/10715762.2018.1468564openalex-snapshot

N-Acetylcysteine as an antioxidant and disulphide breaking agent: the reasons why

inferredcites →https://doi.org/10.1083/jcb.201804161openalex-snapshot

Glutathione metabolism in cancer progression and treatment resistance

inferredcites →https://doi.org/10.1089/ars.2010.3540openalex-snapshot

S-Glutathionylation: From Molecular Mechanisms to Health Outcomes

inferredcites →https://doi.org/10.1091/mbc.e04-07-0560openalex-snapshot

Genetic and Environmental Factors Influencing Glutathione Homeostasis inSaccharomyces cerevisiae

inferredcites →https://doi.org/10.1093/carcin/16.4.869openalex-snapshot

The high non-enzymatic conjugation rates of some glutathione S-transferase (GST) substrates at high glutathione concentrations

inferredcites →https://doi.org/10.1093/jnci/82.9.776openalex-snapshot

Glutathione S-Transferase Activity, Sulfhydryl Group and Glutathione Levels, and DNA Cross-Linking Activity With Chlorambucil in Chronic Lymphocytic Leukemia

inferredcites →https://doi.org/10.1093/jxb/erh202openalex-snapshot

Regulation of calcium signalling and gene expression by glutathione

inferredcites →https://doi.org/10.1097/00001813-199010000-00002openalex-snapshot

Mitomycin C

inferredcites →https://doi.org/10.1097/01.asn.0000042803.28024.92openalex-snapshot

Metabolism of Cisplatin to a Nephrotoxin in Proximal Tubule Cells

inferredcites →https://doi.org/10.1097/fpc.0b013e328313aaa4openalex-snapshot

Relations between polymorphisms in drug-metabolising enzymes and toxicity of chemotherapy with cyclophosphamide, thiotepa and carboplatin

inferredcites →https://doi.org/10.1111/bjh.14541openalex-snapshot

High ten‐year remission rates following rituximab, fludarabine, mitoxantrone and dexamethasone (R‐ FND ) with interferon maintenance in indolent lymphoma: Results of a randomized Study

inferredcites →https://doi.org/10.1111/j.1440-1746.2005.03832.xopenalex-snapshot

Azathioprine and 6‐mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease

inferredcites →https://doi.org/10.1124/dmd.114.061424openalex-snapshot

The Role of Extrahepatic Metabolism in the Pharmacokinetics of the Targeted Covalent Inhibitors Afatinib, Ibrutinib, and Neratinib

inferredcites →https://doi.org/10.1124/dmd.31.12.1499openalex-snapshot

ACETAMINOPHEN-INDUCED HEPATOTOXICITY

inferredcites →https://doi.org/10.1124/jpet.103.052225openalex-snapshot

Role of Cysteine S-Conjugate β-Lyase in the Metabolism of Cisplatin

inferredcites →https://doi.org/10.1124/jpet.108.142208openalex-snapshot

Dehydroalanine Analog of Glutathione: An Electrophilic Busulfan Metabolite That Binds to Human Glutathione S-Transferase A1-1

inferredcites →https://doi.org/10.1124/mol.106.025288openalex-snapshot

Divergent Activities of Human Glutathione Transferases in the Bioactivation of Azathioprine

inferredcites →https://doi.org/10.1124/mol.65.5.1070openalex-snapshot

Tumor Cell Responses to a Novel Glutathione S-Transferase–Activated Nitric Oxide-Releasing Prodrug

inferredcites →https://doi.org/10.1124/pharmrev.120.000121openalex-snapshot

The Nitrogen Mustards

inferredcites →https://doi.org/10.1146/annurev.pharmtox.45.120403.095857openalex-snapshot

GLUTATHIONE TRANSFERASES

inferredcites →https://doi.org/10.1155/2012/736837openalex-snapshot

Glutathione Homeostasis and Functions: Potential Targets for Medical Interventions

inferredcites →https://doi.org/10.1155/2017/9736836openalex-snapshot

Spontaneous Production of Glutathione‐Conjugated Forms of 1,2‐Dichloropropane: Comparative Study on Metabolic Activation Processes of Dihaloalkanes Associated with Occupational Cholangiocarcinoma

inferredcites →https://doi.org/10.1158/1055-9965.epi-09-0871openalex-snapshot

Glutathione Pathway Genetic Polymorphisms and Lung Cancer Survival After Platinum-Based Chemotherapy

inferredcites →https://doi.org/10.1158/1078-0432.ccr-18-3886openalex-snapshot

A Phase I/II Trial of MEC (Mitoxantrone, Etoposide, Cytarabine) in Combination with Ixazomib for Relapsed Refractory Acute Myeloid Leukemia

inferredcites →https://doi.org/10.1172/jci83926openalex-snapshot

Tyrosine kinase inhibitor NVP-BGJ398 functionally improves FGFR3-related dwarfism in mouse model

inferredcites →https://doi.org/10.1186/1472-6882-12-93openalex-snapshot

NF-κB p65 repression by the sesquiterpene lactone, Helenalin, contributes to the induction of autophagy cell death

inferredcites →https://doi.org/10.1186/1756-8722-3-36openalex-snapshot

Pharmacokinetic targeting of intravenous busulfan reduces conditioning regimen related toxicity following allogeneic hematopoietic cell transplantation for acute myelogenous leukemia

inferredcites →https://doi.org/10.1186/s12885-015-1850-4openalex-snapshot

Targeting glycolysis by 3-bromopyruvate improves tamoxifen cytotoxicity of breast cancer cell lines

inferredcites →https://doi.org/10.1186/s12943-022-01530-yopenalex-snapshot

Ferroptosis in cancer therapy: a novel approach to reversing drug resistance

inferredcites →https://doi.org/10.1200/jco.1991.9.10.1731openalex-snapshot

Mitoxantrone, fluorouracil, and high-dose leucovorin: an effective, well-tolerated regimen for metastatic breast cancer.

inferredcites →https://doi.org/10.1200/jco.2012.44.7920openalex-snapshot

Results of a Randomized Trial of Chlorambucil Versus Fludarabine for Patients With Untreated Waldenström Macroglobulinemia, Marginal Zone Lymphoma, or Lymphoplasmacytic Lymphoma

inferredcites →https://doi.org/10.1200/jco.2017.75.5009openalex-snapshot

Phase II Study of BGJ398 in Patients With FGFR-Altered Advanced Cholangiocarcinoma

inferredcites →https://doi.org/10.1201/9781420028485openalex-snapshot

Drug Metabolizing Enzymes

inferredcites →https://doi.org/10.1201/b12556openalex-snapshot

Conjugation Reactions In Drug Metabolism

inferredcites →https://doi.org/10.1289/ehp.834959openalex-snapshot

The Role of Glutathione in Detoxication

inferredcites →https://doi.org/10.13005/bpj/1608openalex-snapshot

Review on Pharmacology of Cisplatin: Clinical Use, Toxicity and Mechanism of Resistance of Cisplatin

inferredcites →https://doi.org/10.1371/journal.pone.0056337openalex-snapshot

The Interaction of the Chemotherapeutic Drug Chlorambucil with Human Glutathione Transferase A1-1: Kinetic and Structural Analysis

inferredcites →https://doi.org/10.1515/bc.2009.033openalex-snapshot

Glutathione dysregulation and the etiology and progression of human diseases

inferredcites →https://doi.org/10.1515/bchm.1997.378.9.951openalex-snapshot

Helenalin, an Anti-Inflammatory Sesquiterpene Lactone from Arnica, Selectively Inhibits Transcription Factor NF-κB

inferredcites →https://doi.org/10.1515/pac-2019-0110openalex-snapshot

Binding motifs of cisplatin interaction with simple biomolecules and aminoacid targets probed by IR ion spectroscopy

inferredcites →https://doi.org/10.18632/oncotarget.11592openalex-snapshot

Glutathione may have implications in the design of 3-bromopyruvate treatment protocols for both fungal and algal infections as well as multiple myeloma

inferredcites →https://doi.org/10.2147/dddt.s3931openalex-snapshot

Structure-based design of anticancer prodrug PABA/NO

inferredcites →https://doi.org/10.2174/0929867054637626openalex-snapshot

Update of the Preclinical Situation of Anticancer Platinum Complexes: Novel Design Strategies and Innovative Analytical Approaches

inferredcites →https://doi.org/10.2174/1381612805666230110214512openalex-snapshot

An Overview of Cyclophosphamide Development and Clinical Applications

inferredcites →https://doi.org/10.2217/pgs.12.185openalex-snapshot

Role of Pharmacogenetics in Busulfan/Cyclophosphamide Conditioning Therapy Prior to Hematopoietic Stem Cell Transplantation

inferredcites →https://doi.org/10.2478/raon-2019-0018openalex-snapshot

Cisplatin and beyond: molecular mechanisms of action and drug resistance development in cancer chemotherapy

inferredcites →https://doi.org/10.3109/03602532.2014.882353openalex-snapshot

Phase 0 and phase III transport in various organs: Combined concept of phases in xenobiotic transport and metabolism

inferredcites →https://doi.org/10.3109/03602538708998299openalex-snapshot

Metabolism of Nitroaromatic Compounds

inferredcites →https://doi.org/10.3109/10428194.2014.963077openalex-snapshot

Past, present and future role of chlorambucil in the treatment of chronic lymphocytic leukemia

inferredcites →https://doi.org/10.3389/fphar.2014.00181openalex-snapshot

Glutathione S-conjugates as prodrugs to target drug-resistant tumors

inferredcites →https://doi.org/10.3389/fphar.2018.01264openalex-snapshot

Metabolism and Bioactivation of Corynoline With Characterization of the Glutathione/Cysteine Conjugate and Evaluation of Its Hepatotoxicity in Mice

inferredcites →https://doi.org/10.3389/fphar.2020.00343openalex-snapshot

The Drug-Resistance Mechanisms of Five Platinum-Based Antitumor Agents

inferredcites →https://doi.org/10.3389/fphar.2020.01297openalex-snapshot

The Emerging Therapeutic Potential of Nitro Fatty Acids and Other Michael Acceptor-Containing Drugs for the Treatment of Inflammation and Cancer

inferredcites →https://doi.org/10.3390/biom10101429openalex-snapshot

Role of Glutathione in Cancer: From Mechanisms to Therapies

inferredcites →https://doi.org/10.3390/cancers11030317openalex-snapshot

Tumor Energy Metabolism and Potential of 3-Bromopyruvate as an Inhibitor of Aerobic Glycolysis: Implications in Tumor Treatment

inferredcites →https://doi.org/10.3390/cancers3011351openalex-snapshot

Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects

inferredcites →https://doi.org/10.3390/ijms21093233openalex-snapshot

Mechanisms of Multidrug Resistance in Cancer Chemotherapy

inferredcites →https://doi.org/10.3390/ijms22020709openalex-snapshot

Delphinidin Increases the Sensitivity of Ovarian Cancer Cell Lines to 3-bromopyruvate

inferredcites →https://doi.org/10.3390/metabo12010088openalex-snapshot

In Vitro Metabolism of Helenalin Acetate and 11α,13-Dihydrohelenalin Acetate: Natural Sesquiterpene Lactones from Arnica

inferredcites →https://doi.org/10.3390/molecules27133995openalex-snapshot

Acid–Base Equilibrium and Self-Association in Relation to High Antitumor Activity of Selected Unsymmetrical Bisacridines Established by Extensive Chemometric Analysis

inferredcites →https://doi.org/10.3390/nu11081926openalex-snapshot

Targeting Glutathione Metabolism: Partner in Crime in Anticancer Therapy

inferredcites →https://doi.org/10.3390/ph14040317openalex-snapshot

Metabolic Profiles of New Unsymmetrical Bisacridine Antitumor Agents in Electrochemical and Enzymatic Noncellular Systems and in Tumor Cells

inferredcites →https://doi.org/10.3390/pharmaceutics5020220openalex-snapshot

Glutathione Transferase (GST)-Activated Prodrugs

inferredcites →https://doi.org/10.3892/ijo.12.4.871openalex-snapshot

Glutathione-related mechanisms in cellular resistance to anticancer drugs.

inferredcites →https://doi.org/10.3892/or.2015.4267openalex-snapshot

N-acetyl-S-(p-chlorophenylcarbamoyl)cysteine induces mitochondrial-mediated apoptosis and suppresses migration in melanoma cells

inferredcites →https://doi.org/10.4161/oxim.3.4.13246openalex-snapshot

Deleterious Effects of Reactive Metabolites

inferredcites →https://doi.org/10.5732/cjc.013.10111openalex-snapshot

Safety and outcome of treatment of metastatic melanoma using 3-bromopyruvate: a concise literature review and case study

inferredcites →https://doi.org/10.5772/1180openalex-snapshot

Topics on Drug Metabolism

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4769330openalex-extracted

Characterizing the Ligandin Properties of Plasmodium Falciparum and Vivax Glutathione Transferase Towards Selected Antimalarial Drugs

inferred← citeshttps://doi.org/10.1002/aoc.7415openalex-snapshot

Late transition metal complexes of ferrocene‐containing nitrogen ligands: Coordination chemistry, electron transfer properties, and tumor cell viability

inferred← citeshttps://doi.org/10.1002/jcph.70095openalex-snapshot

Clinical Impact of Hepatic Impairment on the Pharmacokinetics of Sotorasib and Its Major Metabolites: Implications for Dose Adjustment

inferred← citeshttps://doi.org/10.1007/978-1-0716-5468-2_11openalex-snapshot

Brain Metallomics in Neurodevelopmental Disorders: From Pathophysiology to Therapeutics

inferred← citeshttps://doi.org/10.1007/978-3-031-55287-8_4openalex-snapshot

Metabolic Conversion of Foreign Compounds

inferred← citeshttps://doi.org/10.1007/978-981-95-1549-3_3openalex-snapshot

Surveillance and Monitoring of Humoral Immune Responses

inferred← citeshttps://doi.org/10.1007/978-981-96-4959-4_7openalex-snapshot

Drug Resistance and Novel Targets for Cancer Therapy

inferred← citeshttps://doi.org/10.1007/978-981-96-8260-7_8openalex-snapshot

Mechanistic Understanding of Xenobiotic Detoxification by Plants

inferred← citeshttps://doi.org/10.1007/s00044-023-03116-9openalex-snapshot

Glutathione and glutathione disulfide – their biomedical and pharmaceutical applications

inferred← citeshttps://doi.org/10.1007/s00210-025-03882-wopenalex-snapshot

Investigation of the inhibitory effects of the telomere-targeted compounds on glutathione S-transferase P1

inferred← citeshttps://doi.org/10.1007/s00604-024-06686-6openalex-snapshot

Magnetic nanoparticle-decorated metal organic frameworks for chemiluminescence detection of glutathione

inferred← citeshttps://doi.org/10.1007/s10565-024-09856-7openalex-snapshot

Establishment and characterization of cytochrome P450 1A1 CRISPR/Cas9 Knockout Bovine Foetal Hepatocyte Cell Line (BFH12)

inferred← citeshttps://doi.org/10.1007/s10646-026-03104-wopenalex-snapshot

Interactive effects of ivermectin and nitrogen levels on phytoplankton biomass and stress responses

inferred← citeshttps://doi.org/10.1007/s11255-024-04212-4openalex-snapshot

Advances in nephroprotection: the therapeutic role of selenium, silver, and gold nanoparticles in renal health

inferred← citeshttps://doi.org/10.1007/s12032-025-03132-2openalex-snapshot

Nerolidol-loaded beta-cyclodextrin nanoparticles modulate Nrf-2/Keap1/NF-κB signaling to inhibit DMBA-induced mammary carcinogenesis in Sprague-Dawley rats

inferred← citeshttps://doi.org/10.1007/s12291-025-01382-5openalex-snapshot

Hybrid Coumarins in Oncology: Design Strategies and Multi-target Mechanisms Against Tumor Resistance

inferred← citeshttps://doi.org/10.1007/s12649-026-03656-2openalex-snapshot

Industrial Potential of Cashew Apple Bagasse: A Systematic Review of its Pharmaceutical Appeal and Biosustainability

inferred← citeshttps://doi.org/10.1016/b978-0-323-95488-4.00062-0openalex-snapshot

Free Radicals and Reactive Oxygen Species

inferred← citeshttps://doi.org/10.1016/j.bbrc.2026.154126openalex-snapshot

Oxyresveratrol induces ER stress and growth inhibition associated with glutathione depletion in breast cancer cells

inferred← citeshttps://doi.org/10.1016/j.cbi.2026.112339openalex-snapshot

Identification and characterization of covalent adduct formation of fluorotelomer unsaturated carboxylic acids with histone proteins

inferred← citeshttps://doi.org/10.1016/j.compbiolchem.2023.107981openalex-snapshot

Netting into the Sophoretin pool: An approach to trace GSTP1 inhibitors for reversing chemoresistance

inferred← citeshttps://doi.org/10.1016/j.dmpk.2025.101323openalex-snapshot

Detection of hard electrophilic reactive metabolites formed from alicyclic amines using glutathione trapping

inferred← citeshttps://doi.org/10.1016/j.ejps.2025.107235openalex-snapshot

Pharmacokinetics, metabolism, and toxicity of anisomelic acid and ovatodiolide: Guiding route of administration in preclinical studies

inferred← citeshttps://doi.org/10.1016/j.envadv.2023.100444openalex-snapshot

Microplastics and plastic additives as contaminants of emerging concern: A multi-biomarker approach using Rhinella arenarum tadpoles

inferred← citeshttps://doi.org/10.1016/j.fsi.2024.109418openalex-snapshot

Novel protective aspects of dietary polyphenols against pesticidal toxicity and its prospective application in rice-fish mode: A Review

inferred← citeshttps://doi.org/10.1016/j.fsi.2025.110925openalex-snapshot

Integrative effects of Bacillus tropicus FG2 on growth performance, immunity, gut microbiota, and metabolome in short-finned eel, Anguilla bicolor pacifica

inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.131006openalex-snapshot

Mechanisms of lipopolysaccharide protection in tumor drug–induced macrophage damage

inferred← citeshttps://doi.org/10.1016/j.jbiotec.2025.11.016openalex-snapshot

Emerging strategies for enhanced glutathione biosynthesis and its biomedical applications

inferred← citeshttps://doi.org/10.1016/j.jddst.2026.108220openalex-snapshot

Multifunctional Pluronic nanomedicine: Bridging the gap between chemoresistance and effective cancer therapy

inferred← citeshttps://doi.org/10.1016/j.jep.2024.118539openalex-snapshot

Combining untargeted and targeted metabolomics to reveal the mechanisms of herb pair Anemarrhena asphodeloides Bunge and Phellodendron chinense C. K. Schneid on benign prostatic hyperplasia

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2025.137195openalex-snapshot

Targeted and non-targeted metabolic analysis of chlorpromazine in grass carp as well as the in-silico and metabolomics toxicity assessment

inferred← citeshttps://doi.org/10.1016/j.jinorgbio.2025.113137openalex-snapshot

Assessment of the novel platinum(IV) complexes effects on female rats' kidneys: Possible nephroprotection of resveratrol

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2026.110335openalex-snapshot

Dietary organosulfur compounds and the H2S–polysulfide redox axis: Current evidence and limitations

inferred← citeshttps://doi.org/10.1016/j.jpba.2023.115717openalex-snapshot

The comprehensive mechanism underlying Schisandra polysaccharide in AD-like symptoms of Aβ25-35-induced rats based on hippocampal metabolomics and serum lipidomics techniques

inferred← citeshttps://doi.org/10.1016/j.livres.2025.10.003openalex-snapshot

Sex differences in hepatic enzymes and transporters involved in pharmacokinetics

inferred← citeshttps://doi.org/10.1016/j.marpolbul.2026.119339openalex-snapshot

Azadirachtin-induced oxidative stress in early life stages of the endangered horseshoe crab Tachypleus tridentatus: Implications for coastal conservation

inferred← citeshttps://doi.org/10.1016/j.measurement.2025.119562openalex-snapshot

Cellular electrochemical analysis of cytotoxicity mechanisms of typical antibiotics

inferred← citeshttps://doi.org/10.1016/j.molliq.2023.122468openalex-snapshot

Dissolution thermodynamics and polymorphic transformation behaviors of glutathione

inferred← citeshttps://doi.org/10.1016/j.prerep.2025.100066openalex-snapshot

Ibuprofen: A review on its synthesis, mechanism of action, pharmacological properties, and environmental impact

inferred← citeshttps://doi.org/10.1016/j.rhisph.2026.101270openalex-snapshot

Rhizosphere reprogramming for PAH detoxification: Microbial phytoremediation and engineering strategies

inferred← citeshttps://doi.org/10.1016/j.sajb.2024.11.039openalex-snapshot

The molecular core responses to multiple abiotic stresses in barley (Hordeum vulgare L.): Insights from global transcriptome analysis

inferred← citeshttps://doi.org/10.1016/j.scitotenv.2024.176454openalex-snapshot

Multi-omics analysis reveals the mechanisms by which C6-HSL enhances the resistance of typical functional bacteria in activated sludge to low-temperature stress

inferred← citeshttps://doi.org/10.1016/j.scitotenv.2024.178349openalex-snapshot

Transformative knowledge of polar polycyclic aromatic hydrocarbons via high-resolution mass spectrometry

inferred← citeshttps://doi.org/10.1016/j.talo.2023.100211openalex-snapshot

Applying smartphone camera, spectrophotometry, or ocular analysis-based dipsticks for the detection of glutathione level as a cancer biomarker

inferred← citeshttps://doi.org/10.1016/j.tips.2024.09.009openalex-snapshot

Nitro-fatty acids: promising agents for the development of new cancer therapeutics

inferred← citeshttps://doi.org/10.1016/j.watres.2025.123714openalex-snapshot

Legislative and precautionary approaches to managing pharmaceutical contaminants in Canadian freshwaters

inferred← citeshttps://doi.org/10.1021/acs.chemrev.5c00041openalex-snapshot

Colorectal Cancer at the Crossroads: The Good, the Bad, and the Future of Platinum-Based Drugs

inferred← citeshttps://doi.org/10.1021/acs.est.4c05112openalex-snapshot

Exposure of Polycyclic Aromatic Hydrocarbons (PAHs) and Crude Oil to Atlantic Haddock (Melanogrammus aeglefinus): A Unique Snapshot of the Mercapturic Acid Pathway

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.4c00220openalex-snapshot

Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.4c00962openalex-snapshot

More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5- a ]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5c03580openalex-snapshot

Novel Hybrids of 3-Substituted Coumarin and Phenylsulfonylfuroxan as Potent Antitumor Agents against Wild-Type and Drug-Resistant Nonsmall Cell Lung Cancer Cell Lines

inferred← citeshttps://doi.org/10.1021/acs.jproteome.5c01097openalex-snapshot

What Is in Fetal Bovine Serum Used for Cell Culture? Integrated Proteomics and Peptidomics Reveal Grade-Dependent Molecular Profiles

inferred← citeshttps://doi.org/10.1021/acsomega.3c05377openalex-snapshot

Optimization of 3-Cyano-7-cyclopropylamino-pyrazolo[1,5- a ]pyrimidines toward the Development of an In Vivo Chemical Probe for CSNK2A

inferred← citeshttps://doi.org/10.1021/acsomega.4c00641openalex-snapshot

Lonidamine Increases the Cytotoxic Effect of 1-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-3-(2-chloroethyl)-3-nitrosourea via Energy Inhibition, Disrupting Redox Homeostasis, and Downregulating MGMT Expression in Human Lung Cancer Cell Line

inferred← citeshttps://doi.org/10.1021/acsomega.5c11024openalex-snapshot

Fragment-Based Online OzESI-MS, NMR, and Computational DP4+/DFT Approaches to the Characterization of the Putative Biosynthetic Lipid Precursor of Atkamine from Alaskan Latrunculia Sponges

inferred← citeshttps://doi.org/10.1038/s41419-024-06939-5openalex-snapshot

Oxidative cell death in cancer: mechanisms and therapeutic opportunities

inferred← citeshttps://doi.org/10.1038/s41571-025-01059-1openalex-snapshot

Understanding and overcoming multidrug resistance in cancer

inferred← citeshttps://doi.org/10.1038/s41598-025-21800-1openalex-snapshot

Ameliorative effects of strigolactone on tolerance to lead stress on lettuce (Lactuca sativa L.) plants

inferred← citeshttps://doi.org/10.1038/s41698-025-01090-6openalex-snapshot

Targeted ferroptosis induction enhances chemotherapy efficacy in chemoresistant neuroblastoma

inferred← citeshttps://doi.org/10.1039/d3qi02602gopenalex-snapshot

Pt( iv ) anticancer prodrugs bearing an oxaliplatin scaffold: what do we know about their bioactivity?

inferred← citeshttps://doi.org/10.1039/d4cc00704bopenalex-snapshot

The Chan–Lam-type synthesis of thioimidazolium salts for thiol–(hetero)arene conjugation

inferred← citeshttps://doi.org/10.1039/d5sc03455hopenalex-snapshot

Tracking carboplatin chemoresistance in ovarian cancer by scanning electrochemical microscopy

inferred← citeshttps://doi.org/10.1080/03602532.2025.2582864openalex-snapshot

Phase II metabolism in xenobiotic biotransformation: general mechanisms and the underestimated role of microbial systems

inferred← citeshttps://doi.org/10.1080/09205063.2025.2545089openalex-snapshot

Overcoming resistance: targeted nanomedicine solutions for cancer therapy

inferred← citeshttps://doi.org/10.1080/15287394.2024.2431921openalex-snapshot

Evaluation of safety and efficacy of Brazilian brown propolis from Araucaria sp . in preventing colon cancer

inferred← citeshttps://doi.org/10.1089/ars.2022.0172openalex-snapshot

Redox Regulation of Xenobiotics by Reactive Sulfur and Supersulfide Species

inferred← citeshttps://doi.org/10.1093/lambio/ovaf100openalex-snapshot

Targeting Plasmodium glutathione S-transferases to overcome antimalaria drug resistance in Southern Africa

inferred← citeshttps://doi.org/10.1097/md.0000000000033505openalex-snapshot

Malignancy diseases and kidneys: A nephrologist prospect and updated review

inferred← citeshttps://doi.org/10.1101/2024.06.25.599795openalex-snapshot

Methionine Restriction Reduces Lung Cancer Progression and Increases Chemotherapy Response

inferred← citeshttps://doi.org/10.1111/cts.70201openalex-snapshot

Investigation of the Molecular Mechanisms of Paraoxonase‐2 Mediated Radiotherapy and Chemotherapy Resistance in Oral Squamous Cell Carcinoma

inferred← citeshttps://doi.org/10.1111/febs.17329openalex-snapshot

Spontaneous reversal of small molecule‐induced mitochondrial uncoupling: the case of anilinothiophenes

inferred← citeshttps://doi.org/10.1111/phen.70059openalex-snapshot

When insects fight back: Mechanisms of insecticide resistance and strategies for sustainable pest control

inferred← citeshttps://doi.org/10.1124/jpet.123.001557openalex-snapshot

Suppression of Lung Oxidative Stress, Inflammation, and Fibrosis following Nitrogen Mustard Exposure by the Selective Farnesoid X Receptor Agonist Obeticholic Acid

inferred← citeshttps://doi.org/10.1134/s1068162025601405openalex-snapshot

Coumarins as Bioorganic Building Blocks in Drug Design, Biocatalysis, and Sensing

inferred← citeshttps://doi.org/10.1177/09731296241311346openalex-snapshot

Evaluation of the Pogostone in an Acetaminophen-induced Liver Injury Rat Model

inferred← citeshttps://doi.org/10.1186/s43088-024-00469-xopenalex-snapshot

Proanthocyanidins supplemented diet alter anti-aging-markers and improved lifespan in Drosophila melanogaster model

inferred← citeshttps://doi.org/10.14218/fim.2023.00071openalex-snapshot

Exploring the Molecular Mechanisms and Therapeutic Potentials of Essential Oils: A Systems Biology Approach

inferred← citeshttps://doi.org/10.2147/ijn.s469217openalex-snapshot

What is the Reason That the Pharmacological Future of Chemotherapeutics in the Treatment of Lung Cancer Could Be Most Closely Related to Nanostructures? Platinum Drugs in Therapy of Non-Small and Small Cell Lung Cancer and Their Unexpected, Possible Interactions. The Review

inferred← citeshttps://doi.org/10.2174/0109298673251025230919105818openalex-snapshot

An Update on Glutathione's Biosynthesis, Metabolism, Functions, and Medicinal Purposes

inferred← citeshttps://doi.org/10.2174/0115733947283247240314034927openalex-snapshot

Calixarene in Chemotherapy Drug Delivery: Its Role and Strategies

inferred← citeshttps://doi.org/10.2478/prilozi-2026-0024openalex-snapshot

Xenobiotics Induced Liver Toxicity

inferred← citeshttps://doi.org/10.2478/raon-2025-0001openalex-snapshot

Investigation of GSTP1 and PTEN gene polymorphisms and their association with susceptibility to colorectal cancer

inferred← citeshttps://doi.org/10.31393/reports-vnmedical-2023-27(4)-25openalex-snapshot

Glutathione: synthesis, mechanism of action, antioxidant and detoxifying role

inferred← citeshttps://doi.org/10.31557/apjcp.2023.24.1.133openalex-snapshot

Potential Anti-Cancer Effect of Helenalin as a Natural Bioactive Compound on the Growth and Telomerase Gene Expression in Breast Cancer Cell Line

inferred← citeshttps://doi.org/10.3164/jcbn.24-156openalex-snapshot

Effectiveness of the serum ratio of L-cysteine to glutathione for the prediction of cardiovascular events

inferred← citeshttps://doi.org/10.3389/fphar.2024.1428111openalex-snapshot

Revealing the secrets of Blue Zones

inferred← citeshttps://doi.org/10.3390/antiox12071445openalex-snapshot

Natural Compounds and Glutathione: Beyond Mere Antioxidants

inferred← citeshttps://doi.org/10.3390/antiox12111953openalex-snapshot

The Key Role of GSH in Keeping the Redox Balance in Mammalian Cells: Mechanisms and Significance of GSH in Detoxification via Formation of Conjugates

inferred← citeshttps://doi.org/10.3390/antiox14010094openalex-snapshot

Hypoxia-Induced Reactive Oxygen Species: Their Role in Cancer Resistance and Emerging Therapies to Overcome It

inferred← citeshttps://doi.org/10.3390/biom13040613openalex-snapshot

Inhibition Analysis and High-Resolution Crystal Structure of Mus musculus Glutathione Transferase P1-1

inferred← citeshttps://doi.org/10.3390/biomedicines11082226openalex-snapshot

Glutathione: Lights and Shadows in Cancer Patients

inferred← citeshttps://doi.org/10.3390/biomedicines12081801openalex-snapshot

Overcoming Cancer Resistance: Strategies and Modalities for Effective Treatment

inferred← citeshttps://doi.org/10.3390/biomedicines13071551openalex-snapshot

Interactions of Nedaplatin with Nucleobases and Purine Alkaloids: Their Role in Cancer Therapy

inferred← citeshttps://doi.org/10.3390/books978-3-0365-8666-3openalex-snapshot

Glutathione: Chemistry and Biochemistry

inferred← citeshttps://doi.org/10.3390/cancers16040680openalex-snapshot

Understanding Cancer’s Defense against Topoisomerase-Active Drugs: A Comprehensive Review

inferred← citeshttps://doi.org/10.3390/ijms24065636openalex-snapshot

Heritable Risk and Protective Genetic Components of Glaucoma Medication Non-Adherence

inferred← citeshttps://doi.org/10.3390/molecules28165993openalex-snapshot

Preface to the Special Issue “Glutathione: Chemistry and Biochemistry”

inferred← citeshttps://doi.org/10.3390/molecules29174158openalex-snapshot

Strategic Fluorination to Achieve a Potent, Selective, Metabolically Stable, and Orally Bioavailable Inhibitor of CSNK2

inferred← citeshttps://doi.org/10.3390/molecules31010034openalex-snapshot

Studies on the Complexation of Platinum(II) by Some 4-Nitroisothiazoles and the Cytotoxic Activity of the Resulting Complexes

inferred← citeshttps://doi.org/10.3390/nu16162753openalex-snapshot

The Role of S-Glutathionylation in Health and Disease: A Bird’s Eye View

inferred← citeshttps://doi.org/10.3390/nu18101640openalex-snapshot

Glutathione in Our Diet and Its Role in the Body: From Disease Prevention to Anti-Aging

inferred← citeshttps://doi.org/10.3390/ph19091400openalex-snapshot

Liposomal Morin Attenuates DMH-Associated Colonic Oxidative Stress, Inflammation, and Apoptosis/Autophagy-Related Dysregulation in Rats

inferred← citeshttps://doi.org/10.3390/pharmaceutics18060731openalex-snapshot

Characterization of Atrasentan Metabolic Pathway in Human Liver Microsomes Using Feature-Based Molecular Networking

inferred← citeshttps://doi.org/10.36490/journal-jps.com.v8i2.777openalex-snapshot

Efektivitas Kombinasi Agen Pendeplesi Glutathione (GSH) dan Inhibitor Glutathione S-Transferase (GST) pada Resistensi Cisplatin terhadap Sel Kanker: Systematic Literature Review

inferred← citeshttps://doi.org/10.4236/jct.2026.174021openalex-snapshot

Checkpoint Inhibitor Therapy in Gynecologic Clear Cell Carcinoma: A Narrative Review

inferred← citeshttps://doi.org/10.52589/ijphp-umhxm0onopenalex-snapshot

The Impact of Hydroquinone on Kidney Health

inferred← citeshttps://doi.org/10.53660/539.prw2005openalex-snapshot

Predição in silico do metabolismo de fase 1 da 6b,7-dihidro-5H-ciclopenta[b]nafto[2,1-d]furano-5,6 (9aH)-diona

inferred← citeshttps://doi.org/10.55730/1300-011x.3237openalex-snapshot

Glutathione alleviates boron toxicity by modulating nitrogen metabolism and boronuptake in rice seedlings

inferred← citeshttps://doi.org/10.5772/intechopen.1005592openalex-snapshot

New insights into the roles of cysteine and homocysteine in pathological processes

inferred← citeshttps://doi.org/10.62347/mtlw1449openalex-snapshot

Effects of N-acetylcysteine on hepatocellular carcinoma in chronic hepatitis C

inferred← citeshttps://doi.org/10.63028/10067/2051630151162165141openalex-snapshot

Exploring the therapeutic potential of French maritime pine bark extract in attention-deficit hyperactivity disorder and arterial stiffness

inferred← citeshttps://doi.org/10.70675/7348c90aze74az4eb5z9de1z3462d2923e1bopenalex-snapshot

Evolutionary adaptation of pathogenic Leptospira to superoxide stress

inferred← citeshttps://doi.org/10.70675/c57b83ebz9605z4a40zb52dzf88f09b450edopenalex-snapshot

Development of platinum(IV) conjugates of oxaliplatin and redox modulators as anticancer agents with reduced neurotoxicity

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.