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Soyasaponin II protects against acute liver failure through diminishing YB-1 phosphorylation and Nlrp3-inflammasome priming in mice
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/bies.10300openalex-snapshot
The pleiotropic functions of the Y‐box‐binding protein, YB‐1
inferredcites →https://doi.org/10.1002/hep.28143openalex-snapshot
Impaired monocyte‐macrophage functions and defective toll‐like receptor signaling in hepatitis E virus‐infected pregnant women with acute liver failure
inferredcites →https://doi.org/10.1002/hep.29010openalex-snapshot
Long noncoding RNA HULC modulates the phosphorylation of YB‐1 through serving as a scaffold of extracellular signal–regulated kinase and YB‐1 to enhance hepatocarcinogenesis
inferredcites →https://doi.org/10.1002/prca.201700066openalex-snapshot
Data‐Independent Acquisition‐Based Quantitative Proteomic Analysis Reveals Potential Biomarkers of Kidney Cancer
inferredcites →https://doi.org/10.1002/wrna.1200openalex-snapshot
YB ‐1 protein: functions and regulation
inferredcites →https://doi.org/10.1007/978-1-4939-9130-3_15openalex-snapshot
The LPS/D-Galactosamine-Induced Fulminant Hepatitis Model to Assess the Role of Ligand-Activated Nuclear Receptors on the NLRP3 Inflammasome Pathway In Vivo
inferredcites →https://doi.org/10.1016/j.bbrc.2018.02.018openalex-snapshot
Functional and structural characterization of a β-glucosidase involved in saponin metabolism from intestinal bacteria
inferredcites →https://doi.org/10.1016/j.ccell.2015.04.003openalex-snapshot
Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis
inferredcites →https://doi.org/10.1016/j.cell.2015.02.053openalex-snapshot
Endogenous tRNA-Derived Fragments Suppress Breast Cancer Progression via YBX1 Displacement
inferredcites →https://doi.org/10.1016/j.cmet.2017.06.018openalex-snapshot
Inflammasomes on the Crossroads of Innate Immune Recognition and Metabolic Control
inferredcites →https://doi.org/10.1016/j.fct.2013.07.048openalex-snapshot
The inhibitory effect of black soybean on hepatic cholesterol accumulation in high cholesterol and high fat diet-induced non-alcoholic fatty liver disease
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2013.08.178openalex-snapshot
NLRP3 inflammasome activation in d-galactosamine and lipopolysaccharide-induced acute liver failure: Role of heme oxygenase-1
inferredcites →https://doi.org/10.1016/j.jchromb.2006.08.043openalex-snapshot
Determination of soyasaponins Ba and Bb in human serum by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry
inferredcites →https://doi.org/10.1016/j.jhep.2008.08.009openalex-snapshot
The importance of immune dysfunction in determining outcome in acute liver failure
inferredcites →https://doi.org/10.1016/j.jhep.2015.08.019openalex-snapshot
Macrophage autophagy limits acute toxic liver injury in mice through down regulation of interleukin-1β
inferredcites →https://doi.org/10.1016/j.jhep.2016.11.017openalex-snapshot
Role of the inflammasome in acetaminophen-induced liver injury and acute liver failure
inferredcites →https://doi.org/10.1016/j.kint.2017.03.035openalex-snapshot
Inflammatory cell infiltration and resolution of kidney inflammation is orchestrated by the cold-shock protein Y-box binding protein-1
inferredcites →https://doi.org/10.1016/j.nut.2013.10.017openalex-snapshot
Comparison of bioavailability (I) between soyasaponins and soyasapogenols, and (II) between group A and B soyasaponins
inferredcites →https://doi.org/10.1016/j.nutres.2009.11.004openalex-snapshot
Antidiabetic effects of fermented soybean products on type 2 diabetes
inferredcites →https://doi.org/10.1021/jf100901bopenalex-snapshot
Non-isoflavone Phytochemicals in Soy and Their Health Effects
inferredcites →https://doi.org/10.1021/jf103749ropenalex-snapshot
Effect of Soyasaponins-Rich Extract from Soybean on Acute Alcohol-Induced Hepatotoxicity in Mice
inferredcites →https://doi.org/10.1021/jf503047aopenalex-snapshot
Biological Functionality of Soyasaponins and Soyasapogenols
inferredcites →https://doi.org/10.1021/jf60160a025openalex-snapshot
Soybean saponins. Fate of ingested soybean saponins and the physiological aspect of their hemolytic activity
inferredcites →https://doi.org/10.1038/ni.2919openalex-snapshot
The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response
inferredcites →https://doi.org/10.1038/nmeth.1322openalex-snapshot
Universal sample preparation method for proteome analysis
inferredcites →https://doi.org/10.1038/nrgastro.2015.94openalex-snapshot
Inflammasome activation and function in liver disease
inferredcites →https://doi.org/10.1038/nrmicro3050openalex-snapshot
The abundance and variety of carbohydrate-active enzymes in the human gut microbiota
inferredcites →https://doi.org/10.1038/sj.onc.1208590openalex-snapshot
Akt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells
inferredcites →https://doi.org/10.1038/sj.onc.1210084openalex-snapshot
Akt-dependent nuclear localization of Y-box-binding protein 1 in acquisition of malignant characteristics by human ovarian cancer cells
inferredcites →https://doi.org/10.1053/j.gastro.2011.10.039openalex-snapshot
CCR9+ Macrophages Are Required for Acute Liver Inflammation in Mouse Models of Hepatitis
inferredcites →https://doi.org/10.1053/j.gastro.2012.07.011openalex-snapshot
Pathogenesis of Liver Injury in Acute Liver Failure
inferredcites →https://doi.org/10.1053/j.gastro.2015.08.053openalex-snapshot
RETRACTED: CSF1 Restores Innate Immunity After Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure
inferredcites →https://doi.org/10.1053/j.gastro.2017.12.019openalex-snapshot
Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice
inferredcites →https://doi.org/10.1089/omi.2011.0118openalex-snapshot
clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
inferredcites →https://doi.org/10.1093/jn/134.8.1867openalex-snapshot
Soyasaponin I and Sapongenol B Have Limited Absorption by Caco-2 Intestinal Cells and Limited Bioavailability in Women
inferredcites →https://doi.org/10.1136/gutjnl-2016-313615openalex-snapshot
MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure
inferredcites →https://doi.org/10.1161/circulationaha.107.708016openalex-snapshot
Y-Box Binding Protein-1 Controls CC Chemokine Ligand-5 (CCL5) Expression in Smooth Muscle Cells and Contributes to Neointima Formation in Atherosclerosis-Prone Mice
inferredcites →https://doi.org/10.1371/journal.ppat.1005155openalex-snapshot
The NLRP3 Inflammasome and IL-1β Accelerate Immunologically Mediated Pathology in Experimental Viral Fulminant Hepatitis
inferredcites →https://doi.org/10.2147/ott.s198998openalex-snapshot
Identification of seven-gene signature for prediction of lung squamous cell carcinoma
inferredcites →https://doi.org/10.4049/jimmunol.1300416openalex-snapshot
YB-1 Is an Early and Central Mediator of Bacterial and Sterile Inflammation In Vivo
inferredcites →https://doi.org/10.4268/cjcmm20131330openalex-snapshot
Protective effect of soyasaponins on acute liver injury induced by D-galactosamine and lipopolysaccharide in mice
inferredcites →https://doi.org/10.7150/thno.26540openalex-snapshot
Novel spheroid reservoir bioartificial liver improves survival of nonhuman primates in a toxin-induced model of acute liver failure
inferredcites →https://doi.org/10.7150/thno.30972openalex-snapshot
A Novel TNF-α-Targeting Aptamer for TNF-α-Mediated Acute Lung Injury and Acute Liver Failure
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4638517openalex-extracted
Activation of APE1 Modulates Nrf2, Inhibits Hepatocyte Ferroptosis and Promotes Hepatocyte Autophagy, Thereby Protecting Against Acute Liver Injury
inferred← citeshttps://doi.org/10.1002/bmc.5357openalex-snapshot
Systematic analysis of chemical profiles of Sophorae tonkinensis Radix et Rhizoma in vitro and in vivo using UPLC‐Q‐TOF‐MSE
inferred← citeshttps://doi.org/10.1002/fsn3.2668openalex-snapshot
Protective effect of isoflavones and triterpenoid saponins from pueraria lobata on liver diseases: A review
inferred← citeshttps://doi.org/10.1007/s11596-023-2734-5openalex-snapshot
MicroRNA-29a-3p Prevents Drug-Induced Acute Liver Failure through Inflammation-Related Pyroptosis Inhibition
inferred← citeshttps://doi.org/10.1007/s12272-024-01517-xopenalex-snapshot
Saponins as potential novel NLRP3 inflammasome inhibitors for inflammatory disorders
inferred← citeshttps://doi.org/10.1007/s12975-023-01210-zopenalex-snapshot
Neural Stem Cell Extracellular Vesicles Carrying YBX1 Inhibited Neuronal Pyroptosis Through Increasing m6A-modified GPR30 Stability and Expression in Ischemic Stroke
inferred← citeshttps://doi.org/10.1016/j.aca.2026.345109openalex-snapshot
A high-throughput detection platform for dried blood spots constructed with DESI-MS/MS
inferred← citeshttps://doi.org/10.1016/j.apsb.2021.05.029openalex-snapshot
The gut microbial metabolite, 3,4-dihydroxyphenylpropionic acid, alleviates hepatic ischemia/reperfusion injury via mitigation of macrophage pro-inflammatory activity in mice
inferred← citeshttps://doi.org/10.1016/j.bcp.2023.115467openalex-snapshot
Geraniol ameliorates acute liver failure induced by lipopolysaccharide/D-galactosamine via regulating macrophage polarization and NLRP3 inflammasome activation by PPAR-γ methylation Geraniol alleviates acute liver failure
inferred← citeshttps://doi.org/10.1016/j.cellsig.2023.110750openalex-snapshot
Y-box binding protein 1 promotes chromatin accessibility to aggravate liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.chom.2023.03.018openalex-snapshot
Fusobacterium nucleatum aggravates rheumatoid arthritis through FadA-containing outer membrane vesicles
inferred← citeshttps://doi.org/10.1016/j.fochx.2025.103342openalex-snapshot
Effect of incorporating recycled Ficusaw keotsang Makino seeds on the physicochemical and sensory properties of soymilk and tofu
inferred← citeshttps://doi.org/10.1016/j.fsi.2021.08.018openalex-snapshot
YBX has functional roles in CpG-ODN against cold stress and bacterial infection of Misgurnus anguillicaudatus
inferred← citeshttps://doi.org/10.1016/j.iliver.2024.100133openalex-snapshot
WGCNA combined with machine learning to explore potential biomarkers and treatment strategies for acute liver failure, with experimental validation
inferred← citeshttps://doi.org/10.1016/j.immuni.2023.01.015openalex-snapshot
Pregnancy-induced changes to the gut microbiota drive macrophage pyroptosis and exacerbate septic inflammation
inferred← citeshttps://doi.org/10.1016/j.intimp.2021.108159openalex-snapshot
Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.111529openalex-snapshot
Activation of APE1 modulates Nrf2 protected against acute liver injury by inhibit hepatocyte ferroptosis and promote hepatocyte autophagy
inferred← citeshttps://doi.org/10.1016/j.intimp.2025.114726openalex-snapshot
FTY720 alleviates D-GalN/LPS-induced acute liver failure by regulating the JNK/MAPK pathway
inferred← citeshttps://doi.org/10.1016/j.jare.2021.11.005openalex-snapshot
The multiomics landscape of serum exosomes during the development of sepsis
inferred← citeshttps://doi.org/10.1016/j.lwt.2024.115997openalex-snapshot
Effect and mechanism of pectin for modulating bitter taste of soyasaponin
inferred← citeshttps://doi.org/10.1016/j.mcpro.2025.100972openalex-snapshot
Thermal Proteome Profiling Reveals Meltome Upon NLRP3 Inflammasome Activation
inferred← citeshttps://doi.org/10.1016/j.molimm.2024.02.004openalex-snapshot
Hyperactivation of succinate dehydrogenase promotes pyroptosis of macrophage via ROS-induced GSDMD oligomerization in acute liver failure
inferred← citeshttps://doi.org/10.1016/j.phrs.2020.105388openalex-snapshot
Regulation of the NLRP3 inflammasome with natural products against chemical-induced liver injury
inferred← citeshttps://doi.org/10.1016/j.phrs.2024.107182openalex-snapshot
Targeting epigenetic and post-translational modifications regulating pyroptosis for the treatment of inflammatory diseases
inferred← citeshttps://doi.org/10.1016/j.prp.2026.156423openalex-snapshot
Astragaloside IV ameliorates experimental autoimmune myasthenia gravis through multi-target regulation of immune-microbiota-metabolism network and ferroptosis inhibition
inferred← citeshttps://doi.org/10.1016/j.psj.2021.101663openalex-snapshot
Dietary soya saponin improves the lipid metabolism and intestinal health of laying hens
inferred← citeshttps://doi.org/10.1021/acs.jafc.1c01569openalex-snapshot
Derivatization of Soyasapogenol A through Microbial Transformation for Potential Anti-inflammatory Food Supplements
inferred← citeshttps://doi.org/10.1021/acs.jafc.1c04819openalex-snapshot
Bridging the Gaps between Plant and Human Health: A Systematic Review of Soyasaponins
inferred← citeshttps://doi.org/10.1021/acs.jafc.6c02250openalex-snapshot
Bitterness and Salivary Lubrication Properties of Soyasaponin Acid Hydrolysis Products
inferred← citeshttps://doi.org/10.1038/s41419-023-06150-yopenalex-snapshot
Interfering with Rac1-activation during neonatal monocyte-macrophage differentiation influences the inflammatory responses of M1 macrophages
inferred← citeshttps://doi.org/10.1038/s42003-025-07839-wopenalex-snapshot
Peli1, regulated by m6A modification, suppresses NLRP3 inflammasome activation in atherosclerosis by inhibiting YB-1
inferred← citeshttps://doi.org/10.1097/cm9.0000000000003309openalex-snapshot
Mechanism of action of the nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome and its regulation in liver injury
inferred← citeshttps://doi.org/10.1167/iovs.67.2.42openalex-snapshot
YBX1 Modulated Corneal Neovascularization Induced by Alkali Burn via m 5 C-Dependent Regulation of the STAT3/HIF-1α/VEGFA Axis
inferred← citeshttps://doi.org/10.1177/01926233221076758openalex-snapshot
Possible Cytoprotection of Low Dose Lipopolysaccharide in Rat Thioacetamide-Induced Liver Lesions, Focusing on the Analyses of Hepatic Macrophages and Autophagy
inferred← citeshttps://doi.org/10.1177/03913988221145501openalex-snapshot
Establishment of acute liver failure model in Tibetan miniature pig and verified by dual plasma molecular adsorption system
inferred← citeshttps://doi.org/10.1177/1973798x241304944openalex-snapshot
Vitamin D3 affects the gut metabolomics in lipopolysaccharide-injected mice
inferred← citeshttps://doi.org/10.1186/s12964-021-00765-4openalex-snapshot
ZFP36 promotes VDR mRNA degradation to facilitate cell death in oral and colonic epithelial cells
inferred← citeshttps://doi.org/10.1186/s13578-020-00525-wopenalex-snapshot
Selonsertib, a potential drug for liver failure therapy by rescuing the mitochondrial dysfunction of macrophage via ASK1–JNK–DRP1 pathway
inferred← citeshttps://doi.org/10.18632/aging.204848openalex-snapshot
Swertia cincta Burkill alleviates LPS/D-GalN-induced acute liver failure by modulating apoptosis and oxidative stress signaling pathways
inferred← citeshttps://doi.org/10.21037/atm-21-5767openalex-snapshot
Y-box binding protein 1 regulates liver lipid metabolism by regulating the Wnt/β-catenin signaling pathway
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3135233/v1openalex-snapshot
Peli1, regulated by m 6 A modification, suppresses atherosclerosis progression by inhibiting YB-1-mediated NLRP3 inflammasome activation
inferred← citeshttps://doi.org/10.2147/jir.s344071openalex-snapshot
NLRP3 Inflammasome Pharmacological Inhibitors in Glycyrrhiza for NLRP3-Driven Diseases Treatment: Extinguishing the Fire of Inflammation
inferred← citeshttps://doi.org/10.3389/fcvm.2022.945557openalex-snapshot
YB1 dephosphorylation attenuates atherosclerosis by promoting CCL2 mRNA decay
inferred← citeshttps://doi.org/10.3389/fphar.2020.605065openalex-snapshot
Oleoylethanolamide Protects Against Acute Liver Injury by Regulating Nrf-2/HO-1 and NLRP3 Pathways in Mice
inferred← citeshttps://doi.org/10.3389/fphys.2021.688780openalex-snapshot
Gut Microbiota and Chemical-Induced Acute Liver Injury
inferred← citeshttps://doi.org/10.3389/fpls.2022.1057645openalex-snapshot
A metabolomic platform to identify and quantify polyphenols in coffee and related species using liquid chromatography mass spectrometry
inferred← citeshttps://doi.org/10.3390/foods10061308openalex-snapshot
Metabolomics as a Tool to Study Underused Soy Parts: In Search of Bioactive Compounds
inferred← citeshttps://doi.org/10.3390/vaccines10081307openalex-snapshot
NLRP-3 Inflammasome: A Key Target, but Mostly Overlooked following SARS-CoV-2 Infection
inferred← citeshttps://doi.org/10.6084/m9.figshare.15153782openalex-snapshot
Additional file 2 of ZFP36 promotes VDR mRNA degradation to facilitate cell death in oral and colonic epithelial cells
inferred← citeshttps://doi.org/10.6084/m9.figshare.15153785openalex-snapshot
Additional file 3 of ZFP36 promotes VDR mRNA degradation to facilitate cell death in oral and colonic epithelial cells
inferred← citeshttps://doi.org/10.6084/m9.figshare.15153788openalex-snapshot
Additional file 4 of ZFP36 promotes VDR mRNA degradation to facilitate cell death in oral and colonic epithelial cells
inferred← citeshttps://doi.org/10.6084/m9.figshare.15153791openalex-snapshot
Additional file 5 of ZFP36 promotes VDR mRNA degradation to facilitate cell death in oral and colonic epithelial cells
inferred← citeshttps://doi.org/10.6084/m9.figshare.15153794openalex-snapshot
Additional file 6 of ZFP36 promotes VDR mRNA degradation to facilitate cell death in oral and colonic epithelial cells
inferred← citeshttps://doi.org/10.6084/m9.figshare.15153797openalex-snapshot
Additional file 7 of ZFP36 promotes VDR mRNA degradation to facilitate cell death in oral and colonic epithelial cells
inferred← citeshttps://doi.org/10.6084/m9.figshare.15153800openalex-snapshot
Additional file 8 of ZFP36 promotes VDR mRNA degradation to facilitate cell death in oral and colonic epithelial cells
inferred← citeshttps://doi.org/10.7150/thno.48468openalex-snapshot
A role for intestinal alkaline phosphatase in preventing liver fibrosis
inferred← citeshttps://doi.org/10.7150/thno.58515openalex-snapshot
Fiber scaffold bioartificial liver therapy relieves acute liver failure and extrahepatic organ injury in pigs
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