On the public citation graph

Activation of APE1 Modulates Nrf2, Inhibits Hepatocyte Ferroptosis and Promotes Hepatocyte Autophagy, Thereby Protecting Against Acute Liver Injury

https://doi.org/10.2139/ssrn.4638517
0 signed · 44 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.
Claim with ORCID
Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.
See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/cbin.11849openalex-extracted
tert‐Butylhydroquinone‐induced formation of high‐molecular‐weight p62: A novel mechanism in the activation of Nrf2‐Keap1
inferredcites →https://doi.org/10.1002/hep.28251openalex-extracted
Activation of the p62‐Keap1‐NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
inferredcites →https://doi.org/10.1007/s00018-021-03990-9openalex-extracted
The base excision repair process: comparison between higher and lower eukaryotes
inferredcites →https://doi.org/10.1007/s11626-019-00389-6openalex-extracted
PTEN-mediated mitophagy and APE1 overexpression protects against cardiac hypoxia/reoxygenation injury
inferredcites →https://doi.org/10.1016/j.cell.2013.12.010openalex-extracted
Regulation of Ferroptotic Cancer Cell Death by GPX4
inferredcites →https://doi.org/10.1016/j.cellsig.2017.07.019openalex-extracted
The extracellular role of DNA damage repair protein APE1 in regulation of IL-6 expression
inferredcites →https://doi.org/10.1016/j.celrep.2022.111116openalex-extracted
Acetylation of p62 regulates base excision repair through interaction with APE1
inferredcites →https://doi.org/10.1016/j.chom.2023.04.002openalex-extracted
Liberation of daidzein by gut microbial β-galactosidase suppresses acetaminophen-induced hepatotoxicity in mice
inferredcites →https://doi.org/10.1016/j.dnarep.2018.08.012openalex-extracted
APE1: A skilled nucleic acid surgeon
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2016.02.009openalex-extracted
Antioxidant tert-butylhydroquinone ameliorates arsenic-induced intracellular damages and apoptosis through induction of Nrf2-dependent antioxidant responses as well as stabilization of anti-apoptotic factor Bcl-2 in human keratinocytes
inferredcites →https://doi.org/10.1016/j.jceh.2019.10.005openalex-extracted
Liver Transplant in Acute Liver Failure – Looking Back Over 10 Years
inferredcites →https://doi.org/10.1016/j.jcmgh.2022.02.009openalex-extracted
Hepatic TGFβr1 Deficiency Attenuates Lipopolysaccharide/D-Galactosamine–Induced Acute Liver Failure Through Inhibiting GSK3β–Nrf2–Mediated Hepatocyte Apoptosis and Ferroptosis
inferredcites →https://doi.org/10.1016/j.jhep.2008.08.009openalex-extracted
The importance of immune dysfunction in determining outcome in acute liver failure
inferredcites →https://doi.org/10.1016/j.jhep.2013.03.033openalex-extracted
Decoding cell death signals in liver inflammation
inferredcites →https://doi.org/10.1016/j.jhep.2023.03.016openalex-extracted
ATF4 suppresses hepatocarcinogenesis by inducing SLC7A11 (xCT) to block stress-related ferroptosis
inferredcites →https://doi.org/10.1016/j.marenvres.2017.07.020openalex-extracted
Contrasting effects of a classic Nrf2 activator, tert-butylhydroquinone, on the glutathione-related antioxidant defenses in Pacific oysters, Crassostrea gigas
inferredcites →https://doi.org/10.1016/j.redox.2014.01.023openalex-extracted
Inhibition of APE1/Ref-1 redox activity rescues human retinal pigment epithelial cells from oxidative stress and reduces choroidal neovascularization
inferredcites →https://doi.org/10.1016/j.redox.2021.101970openalex-extracted
Activation of NRF2 by APE1/REF1 is redox-dependent in Barrett's related esophageal adenocarcinoma cells
inferredcites →https://doi.org/10.1016/j.redox.2021.102131openalex-extracted
Fibroblast growth factor 21 attenuates iron overload-induced liver injury and fibrosis by inhibiting ferroptosis
inferredcites →https://doi.org/10.1016/j.redox.2022.102305openalex-extracted
XBP1 deficiency promotes hepatocyte pyroptosis by impairing mitophagy to activate mtDNA-cGAS-STING signaling in macrophages during acute liver injury
inferredcites →https://doi.org/10.1016/j.redox.2022.102349openalex-extracted
Ethyl carbamate triggers ferroptosis in liver through inhibiting GSH synthesis and suppressing Nrf2 activation
inferredcites →https://doi.org/10.1016/s0140-6736(10)60274-7openalex-extracted
Acute liver failure
inferredcites →https://doi.org/10.1038/s41419-019-1543-zopenalex-extracted
Nrf2 signaling and autophagy are complementary in protecting lipopolysaccharide/d-galactosamine-induced acute liver injury by licochalcone A
inferredcites →https://doi.org/10.1038/s41419-021-03804-7openalex-extracted
Small-molecule inhibition of APE1 induces apoptosis, pyroptosis, and necroptosis in non-small cell lung cancer
inferredcites →https://doi.org/10.1038/s41420-022-01173-4openalex-extracted
Regulating Nrf2-GPx4 axis by bicyclol can prevent ferroptosis in carbon tetrachloride-induced acute liver injury in mice
inferredcites →https://doi.org/10.1038/s41598-023-35499-5openalex-extracted
ABCA1 deficiency contributes to podocyte pyroptosis priming via the APE1/IRF1 axis in diabetic kidney disease
inferredcites →https://doi.org/10.1080/15548627.2019.1635383openalex-extracted
Disrupting the TRIB3-SQSTM1 interaction reduces liver fibrosis by restoring autophagy and suppressing exosome-mediated HSC activation
inferredcites →https://doi.org/10.1080/15548627.2020.1810918openalex-extracted
Ferroptosis: machinery and regulation
inferredcites →https://doi.org/10.1080/15548627.2021.1872188openalex-extracted
Rapamycin relieves the cataract caused by ablation of Gja8b through stimulating autophagy in zebrafish
inferredcites →https://doi.org/10.1080/15548627.2021.1886829openalex-extracted
AMPK protects against alcohol-induced liver injury through UQCRC2 to up-regulate mitophagy
inferredcites →https://doi.org/10.1089/ars.2008.2198openalex-extracted
Transcriptional Regulatory Functions of Mammalian AP-Endonuclease (APE1/Ref-1), an Essential Multifunctional Protein
inferredcites →https://doi.org/10.1093/ibd/izaa161openalex-extracted
Inhibition of APE1/Ref-1 Redox Signaling Alleviates Intestinal Dysfunction and Damage to Myenteric Neurons in a Mouse Model of Spontaneous Chronic Colitis
inferredcites →https://doi.org/10.1111/cbdd.12979openalex-extracted
The APE1 redox inhibitor E3330 reduces collective cell migration of human breast cancer cells and decreases chemoinvasion and colony formation when combined with docetaxel
inferredcites →https://doi.org/10.1111/jcmm.17144openalex-extracted
FGF21 alleviates acute liver injury by inducing the SIRT1‐autophagy signalling pathway
inferredcites →https://doi.org/10.1172/jci73939openalex-extracted
mTOR: a pharmacologic target for autophagy regulation
inferredcites →https://doi.org/10.1186/s11658-020-00205-0openalex-extracted
Ferrostatin-1 alleviates lipopolysaccharide-induced acute lung injury via inhibiting ferroptosis
inferredcites →https://doi.org/10.1186/s12967-021-02745-1openalex-extracted
Panaxydol attenuates ferroptosis against LPS-induced acute lung injury in mice by Keap1-Nrf2/HO-1 pathway
inferredcites →https://doi.org/10.18632/oncotarget.19891openalex-extracted
SHYCD induces APE1/Ref-1 subcellular localization to regulate the p53-apoptosis signaling pathway in the prevention and treatment of acute on chronic liver failure
inferredcites →https://doi.org/10.3389/fimmu.2022.793096openalex-extracted
APE1/Ref-1 Role in Inflammation and Immune Response
inferredcites →https://doi.org/10.3390/antiox10101610openalex-extracted
Differential Yet Integral Contributions of Nrf1 and Nrf2 in the Human HepG2 Cells on Antioxidant Cytoprotective Response against Tert-Butylhydroquinone as a Pro-Oxidative Stressor
inferredcites →https://doi.org/10.3748/wjg.15.3086openalex-extracted
An overview of animal models for investigating the pathogenesis and therapeutic strategies in acute hepatic failure
inferredcites →https://doi.org/10.4049/jimmunol.0901856openalex-extracted
Apurinic/Apyrimidinic Endonuclease 1 Is a Key Modulator of Keratinocyte Inflammatory Responses
inferredcites →https://doi.org/10.7150/thno.26540openalex-extracted
Novel spheroid reservoir bioartificial liver improves survival of nonhuman primates in a toxin-induced model of acute liver failure
inferredcites →https://doi.org/10.7150/thno.40128openalex-extracted
Soyasaponin II protects against acute liver failure through diminishing YB-1 phosphorylation and Nlrp3-inflammasome priming in mice
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.