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Mechanisms of 4-Hydroxy-2-nonenal Induced Pro- and Anti-Apoptotic Signaling

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/hep.1840160225openalex-snapshot
Increased 4–Hydroxynonenal Levels in Experimental Alcoholic Liver Disease: Association of Lipid Peroxidation With Liver Fibrogenesis
inferredcites →https://doi.org/10.1002/hep.1840160426openalex-snapshot
Vitamin E Dietary Supplementation Protects Against Carbon Tetrachloride—Induced Chronic Liver Damage and Cirrhosis
inferredcites →https://doi.org/10.1002/hep.510290510openalex-snapshot
Regulation of Rat Hepatocyte Protein Kinase C β Isoenzymes by the Lipid Peroxidation Product 4–Hydroxy–2,3–Nonenal: A Signaling Pathway to Modulate Vesicular Transport of Glycoproteins
inferredcites →https://doi.org/10.1002/jcb.20545openalex-snapshot
Upregulation of Daxx mediates apoptosis in response to oxidative stress
inferredcites →https://doi.org/10.1002/jms.1349openalex-snapshot
Rapid characterization of covalent modifications to rat brain mitochondrial proteins after ex vivo exposure to 4‐hydroxy‐2‐nonenal by liquid chromatography–tandem mass spectrometry using data‐dependent and neutral loss‐driven MS3 acquisition
inferredcites →https://doi.org/10.1002/jms.1725openalex-snapshot
Identification of carbonylation sites in apomyoglobin after exposure to 4‐hydroxy‐2‐nonenal by solid‐phase enrichment and liquid chromatography–electrospray ionization tandem mass spectrometry
inferredcites →https://doi.org/10.1002/pmic.200900116openalex-snapshot
Detection and identification of 4‐hydroxy‐2‐nonenal Schiff‐base adducts along with products of Michael addition using data‐dependent neutral loss‐driven MS3 acquisition: Method evaluation through an in vitro study on cytochrome c oxidase modifications
inferredcites →https://doi.org/10.1006/abbi.1999.1277openalex-snapshot
The Role of Human Glutathione S-Transferases hGSTA1-1 and hGSTA2-2 in Protection against Oxidative Stress
inferredcites →https://doi.org/10.1006/abbi.1999.1479openalex-snapshot
Effects of mGST A4 Transfection on 4-Hydroxynonenal-Mediated Apoptosis and Differentiation of K562 Human Erythroleukemia Cells
inferredcites →https://doi.org/10.1006/abio.1976.9999openalex-snapshot
A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding
inferredcites →https://doi.org/10.1006/taap.2002.9450openalex-snapshot
Role of α Class Glutathione S-Transferases as Antioxidant Enzymes in Rodent Tissues
inferredcites →https://doi.org/10.1016/0891-5849(91)90192-6openalex-snapshot
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
inferredcites →https://doi.org/10.1016/j.abb.2008.09.016openalex-snapshot
4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells
inferredcites →https://doi.org/10.1016/j.atherosclerosis.2003.12.023openalex-snapshot
Glutathione-S-transferase A4-4 modulates oxidative stress in endothelium: possible role in human atherosclerosis
inferredcites →https://doi.org/10.1016/j.bbrc.2005.06.099openalex-snapshot
Depletion of 4-hydroxynonenal in hGSTA4-transfected HLE B-3 cells results in profound changes in gene expression
inferredcites →https://doi.org/10.1016/j.cellsig.2004.09.014openalex-snapshot
Daxx overexpression in T-lymphoblastic Jurkat cells enhances caspase-dependent death receptor- and drug-induced apoptosis in distinct ways
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2004.05.023openalex-snapshot
4-hydroxynonenal and regulation of cell cycle: effects on the pRb/E2F pathway
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2004.05.033openalex-snapshot
Regulation of 4-hydroxynonenal-mediated signaling by glutathione S-transferases
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2008.04.007openalex-snapshot
Self-regulatory role of 4-hydroxynonenal in signaling for stress-induced programmed cell death
inferredcites →https://doi.org/10.1016/j.taap.2003.10.001openalex-snapshot
Physiological role of mGSTA4-4, a glutathione S-transferase metabolizing 4-hydroxynonenal: generation and analysis of mGsta4 null mouse
inferredcites →https://doi.org/10.1016/j.tcb.2005.12.002openalex-snapshot
Daxx: death or survival protein?
inferredcites →https://doi.org/10.1016/j.tox.2005.10.012openalex-snapshot
The course of CCl4 induced hepatotoxicity is altered in mGSTA4-4 null (−/−) mice
inferredcites →https://doi.org/10.1016/s0026-895x(24)12418-2openalex-snapshot
Selective Activation of the c-Jun N-Terminal Protein Kinase Pathway during 4-Hydroxynonenal-Induced Apoptosis of PC12 Cells
inferredcites →https://doi.org/10.1016/s0076-6879(05)01024-4openalex-snapshot
Regulation of 4‐Hydroxynonenal Mediated Signaling By Glutathione S‐Transferases
inferredcites →https://doi.org/10.1016/s0092-8674(00)80294-9openalex-snapshot
Daxx, a Novel Fas-Binding Protein That Activates JNK and Apoptosis
inferredcites →https://doi.org/10.1016/s0092-8674(00)81874-7openalex-snapshot
Apoptosis by Death Factor
inferredcites →https://doi.org/10.1016/s0098-2997(03)00017-7openalex-snapshot
Role of 4-hydroxynonenal in stress-mediated apoptosis signaling
inferredcites →https://doi.org/10.1016/s0098-2997(03)00018-9openalex-snapshot
4-Hydroxynonenal triggers multistep signal transduction cascades for suppression of cellular functions
inferredcites →https://doi.org/10.1016/s0098-2997(03)00021-9openalex-snapshot
4-Hydroxynonenal from pathology to physiology
inferredcites →https://doi.org/10.1016/s0163-7827(03)00014-6openalex-snapshot
4-Hydroxy-2-nonenal: a product and mediator of oxidative stress
inferredcites →https://doi.org/10.1016/s0891-5849(96)00630-2openalex-snapshot
Effect of Oxidative Stress by Iron on 4-Hydroxynonenal Formation and Proliferative Activity In Hepatomas of Different Degrees of Differentiation
inferredcites →https://doi.org/10.1016/s0891-5849(98)00021-5openalex-snapshot
(E)-4-Hydroxy-2-Nonenal May be Involved in the Pathogenesis of Parkinson’s Disease
inferredcites →https://doi.org/10.1021/ac0617971openalex-snapshot
Proteomic Mapping of 4-Hydroxynonenal Protein Modification Sites by Solid-Phase Hydrazide Chemistry and Mass Spectrometry
inferredcites →https://doi.org/10.1021/ac802015mopenalex-snapshot
Characterization of 4-Hydroxy-2-nonenal-Modified Peptides by Liquid Chromatography−Tandem Mass Spectrometry Using Data-Dependent Acquisition: Neutral Loss-Driven MS3 versus Neutral Loss-Driven Electron Capture Dissociation
inferredcites →https://doi.org/10.1021/bi00207a016openalex-snapshot
Michael Addition-Type 4-Hydroxy-2-nonenal Adducts in Modified Low-Density Lipoproteins: Markers for Atherosclerosis
inferredcites →https://doi.org/10.1021/bi060780+openalex-snapshot
Regulation of CD95 (Fas) Expression and Fas-Mediated Apoptotic Signaling in HLE B-3 Cells by 4-Hydroxynonenal
inferredcites →https://doi.org/10.1021/bi701559fopenalex-snapshot
4-Hydroxynonenal Self-Limits Fas-Mediated DISC-Independent Apoptosis by Promoting Export of Daxx from the Nucleus to the Cytosol and Its Binding to Fas
inferredcites →https://doi.org/10.1038/nrc864openalex-snapshot
Live or let die: the cell's response to p53
inferredcites →https://doi.org/10.1038/sj.cdd.4401559openalex-snapshot
Daxx is required for stress-induced cell death and JNK activation
inferredcites →https://doi.org/10.1042/bj20060110openalex-snapshot
Human GSTA1-1 reduces c-Jun N-terminal kinase signalling and apoptosis in Caco-2 cells
inferredcites →https://doi.org/10.1046/j.1471-4159.1997.68052092.xopenalex-snapshot
4‐Hydroxynonenal‐Derived Advanced Lipid Peroxidation End Products Are Increased in Alzheimer's Disease
inferredcites →https://doi.org/10.1073/pnas.0304768101openalex-snapshot
DAXX interacts with heat shock factor 1 during stress activation and enhances its transcriptional activity
inferredcites →https://doi.org/10.1074/jbc.m105928200openalex-snapshot
Apoptosis Signal-regulating Kinase 1 Controls the Proapoptotic Function of Death-associated Protein (Daxx) in the Cytoplasm
inferredcites →https://doi.org/10.1074/jbc.m106838200openalex-snapshot
Accelerated Metabolism and Exclusion of 4-Hydroxynonenal through Induction of RLIP76 and hGST5.8 Is an Early Adaptive Response of Cells to Heat and Oxidative Stress
inferredcites →https://doi.org/10.1074/jbc.m207325200openalex-snapshot
Liver Protection from Apoptosis Requires Both Blockage of Initiator Caspase Activities and Inhibition of ASK1/JNK Pathway via Glutathione S-Transferase Regulation
inferredcites →https://doi.org/10.1074/jbc.m305766200openalex-snapshot
Cells Preconditioned with Mild, Transient UVA Irradiation Acquire Resistance to Oxidative Stress and UVA-induced Apoptosis
inferredcites →https://doi.org/10.1074/jbc.m404512200openalex-snapshot
Tryptophan 621 and Serine 667 Residues of Daxx Regulate Its Nuclear Export during Glucose Deprivation
inferredcites →https://doi.org/10.1074/jbc.m610602200openalex-snapshot
Ethanol-induced Modulation of Hepatocellular Extracellular Signal-regulated Kinase-1/2 Activity via 4-Hydroxynonenal
inferredcites →https://doi.org/10.1074/jbc.m706799200openalex-snapshot
Heat Shock Factor 1 Attenuates 4-Hydroxynonenal-mediated Apoptosis
inferredcites →https://doi.org/10.1074/jbc.m808656200openalex-snapshot
HSF1-mediated BAG3 Expression Attenuates Apoptosis in 4-Hydroxynonenal-treated Colon Cancer Cells via Stabilization of Anti-apoptotic Bcl-2 Proteins
inferredcites →https://doi.org/10.1089/cbr.1995.10.153openalex-snapshot
Inhibition of Melanoma B16-F10 Growth by Lipid Peroxidation Product 4-Hydroxynonenal
inferredcites →https://doi.org/10.1093/ajcn/64.5.761openalex-snapshot
Curcumin protects against 4-hydroxy-2-trans-nonenal–induced cataract formation in rat lenses
inferredcites →https://doi.org/10.1093/emboj/18.5.1321openalex-snapshot
Regulation of JNK signaling by GSTp
inferredcites →https://doi.org/10.1093/gerona/glp165openalex-snapshot
Disruption of the mGsta4 Gene Increases Life Span of C57BL Mice
inferredcites →https://doi.org/10.1093/intimm/9.2.201openalex-snapshot
Anti-Fas IgG1 antibodies recognizing the same epitope of Fas/APO-1 mediate different biological effects in vitro
inferredcites →https://doi.org/10.1101/gad.13.15.1918openalex-snapshot
Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse development
inferredcites →https://doi.org/10.1111/j.1432-1033.2004.04067.xopenalex-snapshot
Transfection with 4‐hydroxynonenal‐metabolizing glutathione S‐transferase isozymes leads to phenotypic transformation and immortalization of adherent cells
inferredcites →https://doi.org/10.1111/j.1530-0277.1994.tb00119.xopenalex-snapshot
Markedly Enhanced Cytochrome P450 2E1 Induction and Lipid Peroxidation Is Associated with Severe Liver Injury in Fish Oil—Ethanol‐Fed Rats
inferredcites →https://doi.org/10.1126/science.275.5296.90openalex-snapshot
Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways
inferredcites →https://doi.org/10.1126/science.281.5384.1860openalex-snapshot
Activation of Apoptosis Signal-Regulating Kinase 1 (ASK1) by the Adapter Protein Daxx
inferredcites →https://doi.org/10.1128/mcb.23.20.7108-7121.2003openalex-snapshot
Daxx Silencing Sensitizes Cells to Multiple Apoptotic Pathways
inferredcites →https://doi.org/10.1128/mcb.23.3.950-960.2003openalex-snapshot
Homeodomain-Interacting Protein Kinase 1 Modulates Daxx Localization, Phosphorylation, and Transcriptional Activity
inferredcites →https://doi.org/10.1161/01.cir.97.11.1071openalex-snapshot
Induction of Rat Aortic Smooth Muscle Cell Growth by the Lipid Peroxidation Product 4-Hydroxy-2-Nonenal
inferredcites →https://doi.org/10.1172/jci118077openalex-snapshot
Experimental liver cirrhosis induced by alcohol and iron.
inferredcites →https://doi.org/10.1172/jci1413openalex-snapshot
HNE interacts directly with JNK isoforms in human hepatic stellate cells.
inferredcites →https://doi.org/10.1179/135100008x308975openalex-snapshot
Daxx inhibits stress-induced apoptosis in cardiac myocytes
inferredcites →https://doi.org/10.1242/jcs.00234openalex-snapshot
RNAi reveals anti-apoptotic and transcriptionally repressive activities of DAXX
inferredcites →https://doi.org/10.2337/db09-0911openalex-snapshot
A Central Role of RLIP76 in Regulation of Glycemic Control
inferredcites →https://doi.org/10.2741/3216openalex-snapshot
PML NBs (ND10) and Daxx: from nuclear structure to protein function

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4794612openalex-extracted
Molecular Mechanism of 4-Hydroxynonenal Induced Cell Death
inferred← citeshttps://doi.org/10.1007/978-1-4419-9940-5_6openalex-snapshot
Neurochemical Aspects of 4-Hydroxynonenal
inferred← citeshttps://doi.org/10.1007/978-81-322-1533-2_8openalex-snapshot
Mechanisms of Chemopreventive Activity of Sulforaphane
inferred← citeshttps://doi.org/10.1007/978-81-322-2035-0_9openalex-snapshot
Oxidative Stress-Induced Lipid Peroxidation: Role in Inflammation
inferred← citeshttps://doi.org/10.1007/s10735-025-10582-5openalex-snapshot
Huangqi Guizhi Wuwu Decoction inhibits ferroptosis to improve cyclophosphamide induced immunosuppression through regulation of arachidonic acid metabolism
inferred← citeshttps://doi.org/10.1007/s11095-017-2154-yopenalex-snapshot
RLIP76 Inhibition: A Promising Developmental Therapy for Neuroblastoma
inferred← citeshttps://doi.org/10.1007/s12011-024-04302-5openalex-snapshot
Zinc Supplementation Reduces ROS Production and Prevents MDMA-Induced Apoptosis in TM3 Leydig Cells via the Inhibition of Pro-Apoptotic Proteins
inferred← citeshttps://doi.org/10.1007/s40618-015-0428-yopenalex-snapshot
4-HNE expression in diabetic rat kidneys and the protective effects of probucol
inferred← citeshttps://doi.org/10.1016/b978-0-323-90905-1.00003-1openalex-snapshot
Oxidative stress and its biological significance
inferred← citeshttps://doi.org/10.1016/j.ab.2025.115767openalex-snapshot
Green fabricated bimetallic zinc ferrite nanoparticles mitigate oxidative stress-induced pathogenesis
inferred← citeshttps://doi.org/10.1016/j.aquatox.2023.106500openalex-snapshot
New insights into the oxidative damage and antioxidant defense mechanism in Manila clams (Ruditapes philippinarum) exposed to 8:2 polyfluoroalkyl phosphate diester stress
inferred← citeshttps://doi.org/10.1016/j.bbadis.2015.01.015openalex-snapshot
On the role of 4-hydroxynonenal in health and disease
inferred← citeshttps://doi.org/10.1016/j.bbadis.2023.166698openalex-snapshot
Myeloid-restricted CD68 deficiency attenuates atherosclerosis via inhibition of ROS-MAPK-apoptosis axis
inferred← citeshttps://doi.org/10.1016/j.bbamem.2012.04.014openalex-snapshot
Protein modification by oxidized phospholipids and hydrolytically released lipid electrophiles: Investigating cellular responses
inferred← citeshttps://doi.org/10.1016/j.bbamem.2013.12.015openalex-snapshot
Plasma membranes as heat stress sensors: From lipid-controlled molecular switches to therapeutic applications
inferred← citeshttps://doi.org/10.1016/j.bbrc.2011.11.113openalex-snapshot
The expression and function of vascular endothelial growth factor in retinal pigment epithelial (RPE) cells is regulated by 4-hydroxynonenal (HNE) and glutathione S-transferaseA4-4
inferred← citeshttps://doi.org/10.1016/j.bbrc.2023.149167openalex-snapshot
Lipid peroxidation: Reactive carbonyl species, protein/DNA adducts, and signaling switches in oxidative stress and cancer
inferred← citeshttps://doi.org/10.1016/j.biocel.2014.05.017openalex-snapshot
Increased expression of prostaglandin reductase 1 in hepatocellular carcinomas from clinical cases and experimental tumors in rats
inferred← citeshttps://doi.org/10.1016/j.biocel.2023.106410openalex-snapshot
Melatonin protects Leydig cells from HT-2 toxin-induced ferroptosis and apoptosis via glucose-6-phosphate dehydrogenase/glutathione -dependent pathway
inferred← citeshttps://doi.org/10.1016/j.exer.2010.11.010openalex-snapshot
Role of 4-hydroxynonenal in epidermal growth factor receptor-mediated signaling in retinal pigment epithelial cells
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2011.05.039openalex-snapshot
Relationship of electrophilic stress to aging
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2012.04.012openalex-snapshot
Role of 4-hydroxynonenal in chemopreventive activities of sulforaphane
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2012.04.021openalex-snapshot
Inhibition of Hydrogen peroxide signaling by 4-hydroxynonenal due to differential regulation of Akt1 and Akt2 contributes to decreases in cell survival and proliferation in hepatocellular carcinoma cells
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2016.09.003openalex-snapshot
Nutrient overload, lipid peroxidation and pancreatic beta cell function
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2016.10.493openalex-snapshot
Regulatory roles of glutathione-S-transferases and 4-hydroxynonenal in stress-mediated signaling and toxicity
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2016.11.010openalex-snapshot
Pro-apoptotic effects of lipid oxidation products: HNE at the crossroads of NF-κB pathway and anti-apoptotic Bcl-2
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2016.11.027openalex-snapshot
Ptgr1 expression is regulated by NRF2 in rat hepatocarcinogenesis and promotes cell proliferation and resistance to oxidative stress
inferred← citeshttps://doi.org/10.1016/j.intimp.2026.116245openalex-snapshot
Targeting the 4-HNE–H₂S pathway as a therapeutic strategy for placental injury in pregnancy with MAFLD
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2022.06.008openalex-snapshot
Hydroxynonenal Causes Hepatocyte Death by Disrupting Lysosomal Integrity in Nonalcoholic Steatohepatitis
inferred← citeshttps://doi.org/10.1016/j.jep.2016.04.048openalex-snapshot
Dillenia suffruticosa dichloromethane root extract induced apoptosis towards MDA-MB-231 triple-negative breast cancer cells
inferred← citeshttps://doi.org/10.1016/j.jprot.2011.05.013openalex-snapshot
Post-translational modifications of mitochondrial aldehyde dehydrogenase and biomedical implications
inferred← citeshttps://doi.org/10.1016/j.labinv.2024.102027openalex-snapshot
Mediation of Ferroptosis Suppressor Protein 1 Expression via 4-Hydroxy-2-Nonenal Accumulation Contributes to Acquisition of Resistance to Apoptosis and Ferroptosis in Diffuse Large B-Cell Lymphoma
inferred← citeshttps://doi.org/10.1016/j.micpath.2023.106423openalex-snapshot
HPV16 E7 protein antagonizes TNF-α-induced apoptosis of cervical cancer cells via Daxx/JNK pathway
inferred← citeshttps://doi.org/10.1016/j.molmet.2018.01.012openalex-snapshot
A role for long-chain acyl-CoA synthetase-4 (ACSL4) in diet-induced phospholipid remodeling and obesity-associated adipocyte dysfunction
inferred← citeshttps://doi.org/10.1016/j.mvr.2011.04.012openalex-snapshot
Hydroxyalkenals and oxidized phospholipids modulation of endothelial cytoskeleton, focal adhesion and adherens junction proteins in regulating endothelial barrier function
inferred← citeshttps://doi.org/10.1016/j.plipres.2019.01.004openalex-snapshot
Hsp70 interactions with membrane lipids regulate cellular functions in health and disease
inferred← citeshttps://doi.org/10.1016/j.prostaglandins.2023.106737openalex-snapshot
Lipid mediated brain disorders: A perspective
inferred← citeshttps://doi.org/10.1016/j.redox.2013.01.007openalex-snapshot
The lipid peroxidation product 4-hydroxy-2-nonenal: Advances in chemistry and analysis
inferred← citeshttps://doi.org/10.1016/j.redox.2016.08.010openalex-snapshot
Lipid mediators involved in the oxidative stress and antioxidant defence of human lung cancer cells
inferred← citeshttps://doi.org/10.1016/j.taap.2015.10.006openalex-snapshot
Antioxidant role of glutathione S-transferases: 4-Hydroxynonenal, a key molecule in stress-mediated signaling
inferred← citeshttps://doi.org/10.1016/j.toxrep.2022.04.002openalex-snapshot
Hexane fraction of Globimetula braunii induces mitochondria-mediated apoptosis in Plasmodium berghei-infected mice
inferred← citeshttps://doi.org/10.1016/j.yexmp.2021.104642openalex-snapshot
Dual role of heme iron in cancer; promotor of carcinogenesis and an inducer of tumour suppression
inferred← citeshttps://doi.org/10.1021/acschemneuro.5b00316openalex-snapshot
Amyloid Plaque-Associated Oxidative Degradation of Uniformly Radiolabeled Arachidonic Acid
inferred← citeshttps://doi.org/10.1021/bi200029wopenalex-snapshot
Modification of Akt2 by 4-Hydroxynonenal Inhibits Insulin-Dependent Akt Signaling in HepG2 Cells
inferred← citeshttps://doi.org/10.1021/tx300100wopenalex-snapshot
4-HNE Adduct Stability Characterized by Collision-Induced Dissociation and Electron Transfer Dissociation Mass Spectrometry
inferred← citeshttps://doi.org/10.1038/cdd.2013.138openalex-snapshot
Cell death and diseases related to oxidative stress:4-hydroxynonenal (HNE) in the balance
inferred← citeshttps://doi.org/10.1038/s41467-020-17862-6openalex-snapshot
ABHD11 maintains 2-oxoglutarate metabolism by preserving functional lipoylation of the 2-oxoglutarate dehydrogenase complex
inferred← citeshttps://doi.org/10.1038/srep32929openalex-snapshot
4-Hydroxy-2-nonenal induces apoptosis by activating ERK1/2 signaling and depleting intracellular glutathione in intestinal epithelial cells
inferred← citeshttps://doi.org/10.1074/jbc.m113.467662openalex-snapshot
4-Hydroxynonenal Induces G2/M Phase Cell Cycle Arrest by Activation of the Ataxia Telangiectasia Mutated and Rad3-related Protein (ATR)/Checkpoint Kinase 1 (Chk1) Signaling Pathway
inferred← citeshttps://doi.org/10.1074/jbc.m113.543942openalex-snapshot
Identification of 5′ AMP-activated Kinase as a Target of Reactive Aldehydes during Chronic Ingestion of High Concentrations of Ethanol
inferred← citeshttps://doi.org/10.1080/10408444.2020.1864721openalex-snapshot
The herbicide paraquat-induced molecular mechanisms in the development of acute lung injury and lung fibrosis
inferred← citeshttps://doi.org/10.1080/13102818.2019.1674690openalex-snapshot
4-Hydroxynonenal (HNE) and hepatic injury related to chronic oxidative stress
inferred← citeshttps://doi.org/10.1093/advances/nmaa072openalex-snapshot
Intake of ω-6 Polyunsaturated Fatty Acid-Rich Vegetable Oils and Risk of Lifestyle Diseases
inferred← citeshttps://doi.org/10.1093/jpp/rgab045openalex-snapshot
Short overview on the relevance of microRNA–reactive oxygen species (ROS) interactions and lipid peroxidation for modulation of oxidative stress-mediated signalling pathways in cancer treatment
inferred← citeshttps://doi.org/10.1093/nar/gkz634openalex-snapshot
DAXX in cancer: phenomena, processes, mechanisms and regulation
inferred← citeshttps://doi.org/10.1111/ijs.12560openalex-snapshot
Heavy Ethanol Consumption Aggravates the Ischemic Cerebral Injury by Inhibiting ALDH2
inferred← citeshttps://doi.org/10.1111/jcmm.15493openalex-snapshot
Byakangelicin protects against carbon tetrachloride–induced liver injury and fibrosis in mice
inferred← citeshttps://doi.org/10.1126/scitranslmed.3009027openalex-snapshot
Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem cell model system
inferred← citeshttps://doi.org/10.1152/ajpcell.00054.2026openalex-snapshot
Molecular signatures of lipid peroxidation in cardiomyopathy: unraveling oxidative mechanisms in cardiac cell dysfunction
inferred← citeshttps://doi.org/10.1152/ajpcell.00101.2016openalex-snapshot
4-Hydroxy-2-nonenal: a critical target in oxidative stress?
inferred← citeshttps://doi.org/10.1155/2013/690545openalex-snapshot
Regulation of NF-B-Induced Inflammatory Signaling by Lipid Peroxidation-Derived Aldehydes
inferred← citeshttps://doi.org/10.1155/2014/360438openalex-snapshot
Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
inferred← citeshttps://doi.org/10.1155/2015/402386openalex-snapshot
Cytotoxic and Antitumor Activity of Sulforaphane: The Role of Reactive Oxygen Species
inferred← citeshttps://doi.org/10.1155/2019/5080843openalex-snapshot
Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis
inferred← citeshttps://doi.org/10.1155/2019/5937326openalex-snapshot
4-Hydroxy-Trans-2-Nonenal in the Regulation of Anti-Oxidative and Pro-Inflammatory Signaling Pathways
inferred← citeshttps://doi.org/10.1155/2021/5537330openalex-snapshot
Ferroptosis in Different Pathological Contexts Seen through the Eyes of Mitochondria
inferred← citeshttps://doi.org/10.11606/d.42.2019.tde-18012019-145440openalex-snapshot
Análise da atividade e expressão da proteína Dicer em condições de estresse de aldeídos: possível papel protetor da enzima ALDH2.
inferred← citeshttps://doi.org/10.11606/t.74.2019.tde-12022019-095141openalex-snapshot
Caracterização proteômica do fígado de bovinos Nelore divergentes para eficiência alimentar
inferred← citeshttps://doi.org/10.1186/1472-6882-14-197openalex-snapshot
Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signalling pathways
inferred← citeshttps://doi.org/10.1186/1479-5876-9-66openalex-snapshot
Ozone acting on human blood yields a hormetic dose-response relationship
inferred← citeshttps://doi.org/10.1186/s12989-021-00430-1openalex-snapshot
The mechanism of cell death induced by silver nanoparticles is distinct from silver cations
inferred← citeshttps://doi.org/10.1371/journal.pbio.2006203openalex-snapshot
Unsolved mysteries: How does lipid peroxidation cause ferroptosis?
inferred← citeshttps://doi.org/10.1371/journal.pone.0041097openalex-snapshot
Cre-Mediated Stress Affects Sirtuin Expression Levels, Peroxisome Biogenesis and Metabolism, Antioxidant and Proinflammatory Signaling Pathways
inferred← citeshttps://doi.org/10.1371/journal.pone.0271467openalex-snapshot
Is there an association between pelvic organ prolapse and oxidative stress? A systematic review
inferred← citeshttps://doi.org/10.15226/2376-4589/2/2/00114openalex-snapshot
Why is Hippocampal CA1 Especially Vulnerable to Ischemia?
inferred← citeshttps://doi.org/10.18632/oncotarget.9821openalex-snapshot
Mitochondrial dysfunction and oxidative stress in aging and cancer
inferred← citeshttps://doi.org/10.21608/mjcu.2019.52514openalex-snapshot
Targeting Heme Oxygenase-1 in Hypothyroidism Induced Reproductive Dysfunction in Adult Male Rats
inferred← citeshttps://doi.org/10.2174/0113892002360132250122164637openalex-snapshot
Umbelliferone Enhances Immune Function in Cyclophosphamide-Induced Immunosuppressed Mice via Histidine and Purine Metabolism Regulation
inferred← citeshttps://doi.org/10.22215/etd/2015-11159openalex-snapshot
NFE2L Regulation BY Endoplasmic Reticulum Stress
inferred← citeshttps://doi.org/10.31083/fbl37139openalex-snapshot
Short Overview on the Involvement of Lipid Peroxidation Product 4-Hydroxynonenal in Diverse Pathways of Cell Death
inferred← citeshttps://doi.org/10.31083/fbl47727openalex-snapshot
Non-Enzymatic Lipid Peroxidation in Cancer Biology: An Overview
inferred← citeshttps://doi.org/10.3109/03602532.2012.713969openalex-snapshot
Inhibition and induction of glutathione S-transferases by flavonoids: possible pharmacological and toxicological consequences
inferred← citeshttps://doi.org/10.3109/10715762.2012.676642openalex-snapshot
Free radical oxidation of cardiolipin: chemical mechanisms, detection and implication in apoptosis, mitochondrial dysfunction and human diseases
inferred← citeshttps://doi.org/10.3109/10715762.2015.1112901openalex-snapshot
The onset of lipid peroxidation in rheumatoid arthritis: consequences and monitoring
inferred← citeshttps://doi.org/10.3389/fcimb.2022.999569openalex-snapshot
Publication trends of research on sepsis and programmed cell death during 2002–2022: A 20-year bibliometric analysis
inferred← citeshttps://doi.org/10.3389/fneur.2023.1287559openalex-snapshot
Iron homeostasis and post-hemorrhagic hydrocephalus: a review
inferred← citeshttps://doi.org/10.3389/fonc.2019.01247openalex-snapshot
AMPK-ERK/CARM1 Signaling Pathways Affect Autophagy of Hepatic Cells in Samples of Liver Cancer Patients
inferred← citeshttps://doi.org/10.3389/fphar.2023.1122632openalex-snapshot
Acetaminophen-induced liver injury: Molecular mechanism and treatments from natural products
inferred← citeshttps://doi.org/10.3389/fphys.2018.01739openalex-snapshot
Oxidative Stress and Neonatal Respiratory Extracorporeal Membrane Oxygenation
inferred← citeshttps://doi.org/10.3389/fpsyt.2022.813304openalex-snapshot
Oxidative Stress in Autism Spectrum Disorder—Current Progress of Mechanisms and Biomarkers
inferred← citeshttps://doi.org/10.3390/antiox10050778openalex-snapshot
Hidrox® Counteracts Cyclophosphamide-Induced Male Infertility through NRF2 Pathways in a Mouse Model
inferred← citeshttps://doi.org/10.3390/antiox11102071openalex-snapshot
Detrimental Effects of Lipid Peroxidation in Type 2 Diabetes: Exploring the Neutralizing Influence of Antioxidants
inferred← citeshttps://doi.org/10.3390/antiox13020232openalex-snapshot
Reactive Carbonyl Species and Protein Lipoxidation in Atherogenesis
inferred← citeshttps://doi.org/10.3390/antiox13101249openalex-snapshot
Oxidative Stress in Cataract Formation: Is There a Treatment Approach on the Horizon?
inferred← citeshttps://doi.org/10.3390/antiox14010078openalex-snapshot
Lipid Oxidation at the Crossroads: Oxidative Stress and Neurodegeneration Explored in Caenorhabditis elegans
inferred← citeshttps://doi.org/10.3390/antiox15030369openalex-snapshot
The Role of Ferroptosis in Diabetes Pathogenesis: Therapeutic Implications of Hydrogen Sulfide and Its Reactive Metabolites
inferred← citeshttps://doi.org/10.3390/antiox9040303openalex-snapshot
N-Acetyl Serotonin Alleviates Oxidative Damage by Activating Nuclear Factor Erythroid 2-Related Factor 2 Signaling in Porcine Enterocytes
inferred← citeshttps://doi.org/10.3390/biom12010145openalex-snapshot
Chemistry and Biochemistry Aspects of the 4-Hydroxy-2,3-trans-nonenal
inferred← citeshttps://doi.org/10.3390/biomedicines12040918openalex-snapshot
The Role of Cdo1 in Ferroptosis and Apoptosis in Cancer
inferred← citeshttps://doi.org/10.3390/cells11050829openalex-snapshot
Hsp70 in Redox Homeostasis
inferred← citeshttps://doi.org/10.3390/genes8100281openalex-snapshot
Eco-Friendly Formulated Zinc Oxide Nanoparticles: Induction of Cell Cycle Arrest and Apoptosis in the MCF-7 Cancer Cell Line
inferred← citeshttps://doi.org/10.3390/ijms22041651openalex-snapshot
Geniposide Improves Diabetic Nephropathy by Enhancing ULK1-Mediated Autophagy and Reducing Oxidative Stress through AMPK Activation
inferred← citeshttps://doi.org/10.3390/ijms251910672openalex-snapshot
Phospholipids, Sphingolipids, and Cholesterol-Derived Lipid Mediators and Their Role in Neurological Disorders
inferred← citeshttps://doi.org/10.3390/livers2040023openalex-snapshot
Role of Oxidative Stress in Liver Disorders
inferred← citeshttps://doi.org/10.3390/nu15051255openalex-snapshot
Gamma-Muricholic Acid Inhibits Nonalcoholic Steatohepatitis: Abolishment of Steatosis-Dependent Peroxidative Impairment by FXR/SHP/LXRα/FASN Signaling
inferred← citeshttps://doi.org/10.3892/etm.2018.6633openalex-snapshot
Oxidative status of cardinal ligament in pelvic organ prolapse
inferred← citeshttps://doi.org/10.4103/2394-8108.195279openalex-snapshot
Targeting oxidative stress for the treatment of ischemic stroke: Upstream and downstream therapeutic strategies
inferred← citeshttps://doi.org/10.5897/ajpp12.209openalex-snapshot
Advances in the study of the biological function of Daxx
inferred← citeshttps://doi.org/10.6084/m9.figshare.16815915openalex-snapshot
Additional file 1 of The mechanism of cell death induced by silver nanoparticles is distinct from silver cations
inferred← citeshttps://doi.org/10.70675/7ab2bcc8z16d2z420cz92f9zb3fd52371382openalex-snapshot
Activités cytotoxiques et pro-oxydantes d'acides gras à très longue chaîne sur des oligodendrocytes murins sauvages et déficients en Abcd1 et Acox1 : application à la physiopathologie de l'X-ALD et de la P-NALD
inferred← citeshttps://doi.org/10.7150/thno.62797openalex-snapshot
IRGM/Irgm1 facilitates macrophage apoptosis through ROS generation and MAPK signal transduction: Irgm1+/- mice display increases atherosclerotic plaque stability
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