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PPARs and Lipid Ligands in Inflammation and Metabolism
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2 of the 200 references listed on this page are in the Retraction Watch database as retracted (export 2026-11-04): 10.1074/jbc.c000517200 (notice 2013-10-18), 10.1074/jbc.m007237200 (notice 2019-12-02).
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1001/archinternmed.2010.207openalex-snapshot
Rosiglitazone Revisited
inferredcites →https://doi.org/10.1001/jama.296.21.joc60158openalex-snapshot
Effect of Pioglitazone Compared With Glimepiride on Carotid Intima-Media Thickness in Type 2 Diabetes
inferredcites →https://doi.org/10.1001/jama.298.10.1180openalex-snapshot
Pioglitazone and Risk of Cardiovascular Events in Patients With Type 2 Diabetes Mellitus
inferredcites →https://doi.org/10.1002/9780470123041.ch7openalex-snapshot
The Stereochemistry of the Reactions of Lipoxygenases and Their Metabolites. Proposed Nomenclature of Lipoxygenases and Related Enzymes
inferredcites →https://doi.org/10.1002/eji.200636625openalex-snapshot
IL‐13 induces expression of CD36 in human monocytes through PPARγ activation
inferredcites →https://doi.org/10.1002/j.1460-2075.1992.tb05141.xopenalex-snapshot
Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors.
inferredcites →https://doi.org/10.1002/j.1460-2075.1996.tb00736.xopenalex-snapshot
TIF2, a 160 kDa transcriptional mediator for the ligand‐dependent activation function AF‐2 of nuclear receptors.
inferredcites →https://doi.org/10.1002/j.1460-2075.1996.tb00918.xopenalex-snapshot
PPARalpha and PPARgamma activators direct a distinct tissue‐specific transcriptional response via a PPRE in the lipoprotein lipase gene.
inferredcites →https://doi.org/10.1006/bbrc.1998.8303openalex-snapshot
Dietary Conjugated Linoleic Acid Normalizes Impaired Glucose Tolerance in the Zucker Diabetic Fattyfa/faRat
inferredcites →https://doi.org/10.1006/bbrc.1999.1968openalex-snapshot
Activation of PPARα or γ Reduces Secretion of Matrix Metalloproteinase 9 but Not Interleukin 8 from Human Monocytic THP-1 Cells
inferredcites →https://doi.org/10.1007/978-1-4419-9072-3_22openalex-snapshot
A Paradigm for Gene Regulation: Inflammation, NF-κB and PPAR
inferredcites →https://doi.org/10.1007/s00018-003-3216-3openalex-snapshot
Peroxisome proliferator-activated receptor a target genes
inferredcites →https://doi.org/10.1007/s11010-005-9052-zopenalex-snapshot
Aspects of the regulatory mechanisms of PPAR functions: Analysis of a bidirectional response element and regulation by sumoylation
inferredcites →https://doi.org/10.1007/s11745-009-3332-4openalex-snapshot
Nitro‐fatty Acids Occur in Human Plasma in the Picomolar Range: a Targeted Nitro‐lipidomics GC–MS/MS Study
inferredcites →https://doi.org/10.1016/0005-2760(85)90166-3openalex-snapshot
Formation of 15-HETE as a major hydroxyeicosatetraenoic acid in the atherosclerotic vessel wall
inferredcites →https://doi.org/10.1016/0006-291x(91)91645-sopenalex-snapshot
Two -acting regulatory sequences in the peroxisome proliferator-responsive enhancer region of rat acyl-CoA oxidase gene
inferredcites →https://doi.org/10.1016/0006-291x(92)90500-kopenalex-snapshot
Prostaglandin F2α inhibits the differentiation of adipocyte precursors in primary culture
inferredcites →https://doi.org/10.1016/0021-9150(71)90025-6openalex-snapshot
Lipids of human atheroma Part 4. Characterisation of a new group of polar sterol esters from human atherosclerotic plaques
inferredcites →https://doi.org/10.1016/0021-9150(71)90026-8openalex-snapshot
Lipids of human atheroma Part 5. The occurrence of a new group of polar sterol esters in various stages of human atherosclerosis
inferredcites →https://doi.org/10.1016/0021-9150(89)90204-9openalex-snapshot
Formation of 15-hydroxyeicosatetraenoic acid (15-HETE) as the predominant eicosanoid in aortas from Watanabe Heritable Hyperlipidemic and cholesterol-fed rabbits
inferredcites →https://doi.org/10.1016/0092-8674(90)90395-uopenalex-snapshot
Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone
inferredcites →https://doi.org/10.1016/0092-8674(90)90396-vopenalex-snapshot
Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction
inferredcites →https://doi.org/10.1016/0092-8674(90)90397-wopenalex-snapshot
Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor
inferredcites →https://doi.org/10.1016/0092-8674(94)90006-xopenalex-snapshot
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
inferredcites →https://doi.org/10.1016/0092-8674(94)90380-8openalex-snapshot
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
inferredcites →https://doi.org/10.1016/0092-8674(95)90193-0openalex-snapshot
15-Deoxy-Δ12,14-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
inferredcites →https://doi.org/10.1016/0092-8674(95)90194-9openalex-snapshot
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation
inferredcites →https://doi.org/10.1016/0092-8674(95)90199-xopenalex-snapshot
The nuclear receptor superfamily: The second decade
inferredcites →https://doi.org/10.1016/0952-3278(92)90178-lopenalex-snapshot
Biological activities and mechanisms of action of PGJ2 and related compounds: an update
inferredcites →https://doi.org/10.1016/j.bbrc.2009.07.030openalex-snapshot
Nitrated fatty acids prevent TNFα-stimulated inflammatory and atherogenic responses in endothelial cells
inferredcites →https://doi.org/10.1016/j.biochi.2004.11.010openalex-snapshot
Phosphorylation of PPARs: from molecular characterization to physiological relevance
inferredcites →https://doi.org/10.1016/j.cell.2005.06.029openalex-snapshot
Molecular Determinants of Crosstalk between Nuclear Receptors and Toll-like Receptors
inferredcites →https://doi.org/10.1016/j.cell.2007.02.050openalex-snapshot
Opposing Effects of Retinoic Acid on Cell Growth Result from Alternate Activation of Two Different Nuclear Receptors
inferredcites →https://doi.org/10.1016/j.cell.2007.05.009openalex-snapshot
High-Resolution Profiling of Histone Methylations in the Human Genome
inferredcites →https://doi.org/10.1016/j.cell.2009.05.036openalex-snapshot
Identification of a Physiologically Relevant Endogenous Ligand for PPARα in Liver
inferredcites →https://doi.org/10.1016/j.cellsig.2008.10.010openalex-snapshot
Lysophosphatidic acid signaling in airway epithelium: Role in airway inflammation and remodeling
inferredcites →https://doi.org/10.1016/j.clnu.2005.12.008openalex-snapshot
CLA and n-3 PUFA differentially modulate clinical activity and colonic PPAR-responsive gene expression in a pig model of experimental IBD
inferredcites →https://doi.org/10.1016/j.cmet.2005.04.002openalex-snapshot
“New” hepatic fat activates PPARα to maintain glucose, lipid, and cholesterol homeostasis
inferredcites →https://doi.org/10.1016/j.cmet.2007.06.010openalex-snapshot
PPARγ Activation Primes Human Monocytes into Alternative M2 Macrophages with Anti-inflammatory Properties
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2008.09.002openalex-snapshot
PPARα ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-κB and AP-1 pathways
inferredcites →https://doi.org/10.1016/j.immuni.2010.02.008openalex-snapshot
Identification and Characterization of Enhancers Controlling the Inflammatory Gene Expression Program in Macrophages
inferredcites →https://doi.org/10.1016/j.it.2007.09.003openalex-snapshot
Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms
inferredcites →https://doi.org/10.1016/j.jchromb.2007.12.003openalex-snapshot
Quantitative determination of cyclic phosphatidic acid in human serum by LC/ESI/MS/MS
inferredcites →https://doi.org/10.1016/j.jchromb.2008.12.062openalex-snapshot
Specific GC–MS/MS stable-isotope dilution methodology for free 9- and 10-nitro-oleic acid in human plasma challenges previous LC–MS/MS reports
inferredcites →https://doi.org/10.1016/j.molcel.2006.11.022openalex-snapshot
Parallel SUMOylation-Dependent Pathways Mediate Gene- and Signal-Specific Transrepression by LXRs and PPARγ
inferredcites →https://doi.org/10.1016/j.molcel.2007.09.011openalex-snapshot
Facultative Heterochromatin: Is There a Distinctive Molecular Signature?
inferredcites →https://doi.org/10.1016/j.molcel.2010.07.022openalex-snapshot
Phospholipase D2-Dependent Inhibition of the Nuclear Hormone Receptor PPARγ by Cyclic Phosphatidic Acid
inferredcites →https://doi.org/10.1016/j.plefa.2007.08.001openalex-snapshot
The two faces of the 15-lipoxygenase in atherosclerosis
inferredcites →https://doi.org/10.1016/j.plefa.2010.02.021openalex-snapshot
Conjugated linoleic acid and inflammatory cell signalling
inferredcites →https://doi.org/10.1016/j.prostaglandins.2005.10.004openalex-snapshot
Lipoxin biosynthesis in inflammatory bowel disease
inferredcites →https://doi.org/10.1016/s0002-9440(10)65540-xopenalex-snapshot
Macrophages in Human Atheroma Contain PPARγ
inferredcites →https://doi.org/10.1016/s0005-2760(98)00121-0openalex-snapshot
Conjugated linoleic acid activates peroxisome proliferator-activated receptor α and β subtypes but does not induce hepatic peroxisome proliferation in Sprague–Dawley rats
inferredcites →https://doi.org/10.1016/s0021-9258(17)41942-9openalex-snapshot
Molecular cloning and expression of a cDNA of the bovine prostaglandin F2 alpha receptor.
inferredcites →https://doi.org/10.1016/s0021-9258(17)42265-4openalex-snapshot
Cloning and expression of a cDNA for mouse prostaglandin F receptor.
inferredcites →https://doi.org/10.1016/s0021-9258(17)44287-6openalex-snapshot
Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro.
inferredcites →https://doi.org/10.1016/s0022-3565(24)37268-4openalex-snapshot
Identification of High-Affinity Binding Sites for the Insulin Sensitizer Rosiglitazone (BRL-49653) in Rodent and Human Adipocytes Using a Radioiodinated Ligand for Peroxisomal Proliferator-Activated Receptor γ
inferredcites →https://doi.org/10.1016/s0026-895x(25)08890-xopenalex-snapshot
Enhancement of adipocyte differentiation by an insulin-sensitizing agent.
inferredcites →https://doi.org/10.1016/s0026-895x(25)08970-9openalex-snapshot
Adipocyte fatty acid-binding protein: regulation of gene expression in vivo and in vitro by an insulin-sensitizing agent.
inferredcites →https://doi.org/10.1016/s0090-6980(02)00047-3openalex-snapshot
Lipoxins and aspirin-triggered 15-epi-lipoxin biosynthesis: an update and role in anti-inflammation and pro-resolution
inferredcites →https://doi.org/10.1016/s0090-6980(02)00050-3openalex-snapshot
Prostaglandin catabolizing enzymes
inferredcites →https://doi.org/10.1016/s0092-8674(00)81118-6openalex-snapshot
A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors
inferredcites →https://doi.org/10.1016/s0092-8674(00)81574-3openalex-snapshot
Oxidized LDL Regulates Macrophage Gene Expression through Ligand Activation of PPARγ
inferredcites →https://doi.org/10.1016/s0092-8674(00)81575-5openalex-snapshot
PPARγ Promotes Monocyte/Macrophage Differentiation and Uptake of Oxidized LDL
inferredcites →https://doi.org/10.1016/s0092-8674(00)82001-2openalex-snapshot
The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases
inferredcites →https://doi.org/10.1016/s0092-8674(03)00269-1openalex-snapshot
Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity
inferredcites →https://doi.org/10.1016/s0163-7827(96)00008-2openalex-snapshot
Biosynthesis, metabolization and biological importance of the primary 15-lipoxygenase metabolites 15-hydro(pero)xy-5Z,8Z,11Z,13E-eicosatetraenoic acid and 13-hydro(pero)xy-9Z,11E-octadecadienoic acid
inferredcites →https://doi.org/10.1016/s0165-6147(00)01548-0openalex-snapshot
Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications
inferredcites →https://doi.org/10.1016/s0955-0674(98)80014-8openalex-snapshot
Co-activators and co-repressors in the integration of transcriptional responses
inferredcites →https://doi.org/10.1016/s0968-0004(01)01800-xopenalex-snapshot
Nuclear-receptor interactions on DNA-response elements
inferredcites →https://doi.org/10.1016/s0969-2126(03)00133-3openalex-snapshot
Activation of Nuclear Receptors
inferredcites →https://doi.org/10.1016/s1097-2765(00)80066-0openalex-snapshot
Phosphorylation of NF-κB p65 by PKA Stimulates Transcriptional Activity by Promoting a Novel Bivalent Interaction with the Coactivator CBP/p300
inferredcites →https://doi.org/10.1016/s1097-2765(00)80209-9openalex-snapshot
PPARγ Is Required for Placental, Cardiac, and Adipose Tissue Development
inferredcites →https://doi.org/10.1016/s1097-2765(00)80211-7openalex-snapshot
PPARγ Is Required for the Differentiation of Adipose Tissue In Vivo and In Vitro
inferredcites →https://doi.org/10.1016/s1097-2765(00)80448-7openalex-snapshot
Asymmetry in the PPARγ/RXRα Crystal Structure Reveals the Molecular Basis of Heterodimerization among Nuclear Receptors
inferredcites →https://doi.org/10.1016/s1097-2765(00)80467-0openalex-snapshot
Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors
inferredcites →https://doi.org/10.1016/s1097-2765(01)00164-2openalex-snapshot
A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in Cholesterol Efflux and Atherogenesis
inferredcites →https://doi.org/10.1016/s1388-1981(02)00126-9openalex-snapshot
Conjugated linoleic acid decreases production of pro-inflammatory products in macrophages: evidence for a PPARγ-dependent mechanism
inferredcites →https://doi.org/10.1016/s1534-5807(03)00274-0openalex-snapshot
Genetic Modulation of PPARγ Phosphorylation Regulates Insulin Sensitivity
inferredcites →https://doi.org/10.1021/bi7018699openalex-snapshot
Ligand Specificity of Nuclear Hormone Receptors: Sifting through Promiscuity
inferredcites →https://doi.org/10.1021/bi9816094openalex-snapshot
Ligand Selectivity of the Peroxisome Proliferator-Activated Receptor α
inferredcites →https://doi.org/10.1038/22572openalex-snapshot
Interleukin-4-dependent production of PPAR-γ ligands in macrophages by 12/15-lipoxygenase
inferredcites →https://doi.org/10.1038/25931openalex-snapshot
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ
inferredcites →https://doi.org/10.1038/26040openalex-snapshot
Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators
inferredcites →https://doi.org/10.1038/3099openalex-snapshot
A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
inferredcites →https://doi.org/10.1038/31701openalex-snapshot
Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPARγ activators
inferredcites →https://doi.org/10.1038/332166a0openalex-snapshot
Oncogene jun encodes a sequence-specific trans- activator similar to AP-1
inferredcites →https://doi.org/10.1038/34178openalex-snapshot
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
inferredcites →https://doi.org/10.1038/34184openalex-snapshot
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
inferredcites →https://doi.org/10.1038/353670a0openalex-snapshot
Phosphorylation of c-jun mediated by MAP kinases
inferredcites →https://doi.org/10.1038/354494a0openalex-snapshot
Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73
inferredcites →https://doi.org/10.1038/355446a0openalex-snapshot
Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling
inferredcites →https://doi.org/10.1038/370226a0openalex-snapshot
Activation of cAMP and mitogen responsive genes relies on a common nuclear factor
inferredcites →https://doi.org/10.1038/375377a0openalex-snapshot
Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α
inferredcites →https://doi.org/10.1038/378681a0openalex-snapshot
Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid
inferredcites →https://doi.org/10.1038/378690a0openalex-snapshot
A structural role for hormone in the thyroid hormone receptor
inferredcites →https://doi.org/10.1038/384039a0openalex-snapshot
The PPARα–leukotriene B4 pathway to inflammation control
inferredcites →https://doi.org/10.1038/39645openalex-snapshot
Molecular basis of agonism and antagonism in the oestrogen receptor
inferredcites →https://doi.org/10.1038/417563aopenalex-snapshot
Transcription coactivator TRAP220 is required for PPARγ2-stimulated adipogenesis
inferredcites →https://doi.org/10.1038/42652openalex-snapshot
The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function
inferredcites →https://doi.org/10.1038/42750openalex-snapshot
A signature motif in transcriptional co-activators mediates binding to nuclear receptors
inferredcites →https://doi.org/10.1038/47069openalex-snapshot
The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors
inferredcites →https://doi.org/10.1038/47520openalex-snapshot
Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase
inferredcites →https://doi.org/10.1038/83328openalex-snapshot
The role of PPAR-γ in macrophage differentiation and cholesterol uptake
inferredcites →https://doi.org/10.1038/83336openalex-snapshot
PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
inferredcites →https://doi.org/10.1038/83348openalex-snapshot
PPAR-α and PPAR-γ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway
inferredcites →https://doi.org/10.1038/9550openalex-snapshot
Inducible cyclooxygenase may have anti-inflammatory properties
inferredcites →https://doi.org/10.1038/emboj.2010.197openalex-snapshot
The nuclear receptor PPARγ individually responds to serotonin‐ and fatty acid‐metabolites
inferredcites →https://doi.org/10.1038/nature03988openalex-snapshot
A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ
inferredcites →https://doi.org/10.1038/nature05894openalex-snapshot
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
inferredcites →https://doi.org/10.1038/nature07413openalex-snapshot
Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA
inferredcites →https://doi.org/10.1038/nature07829openalex-snapshot
Histone modifications at human enhancers reflect global cell-type-specific gene expression
inferredcites →https://doi.org/10.1038/nature09291openalex-snapshot
Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5
inferredcites →https://doi.org/10.1038/ng1966openalex-snapshot
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
inferredcites →https://doi.org/10.1038/ni1018openalex-snapshot
Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-γ and RelA
inferredcites →https://doi.org/10.1038/ni1056openalex-snapshot
Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway
inferredcites →https://doi.org/10.1038/nm.2101openalex-snapshot
Pharmacological correction of a defect in PPAR-γ signaling ameliorates disease severity in Cftr-deficient mice
inferredcites →https://doi.org/10.1038/nm1026openalex-snapshot
Peroxisome proliferator–activated receptor-δ attenuates colon carcinogenesis
inferredcites →https://doi.org/10.1038/nm1278openalex-snapshot
Thiazolidinediones expand body fluid volume through PPARγ stimulation of ENaC-mediated renal salt absorption
inferredcites →https://doi.org/10.1038/sj.bjp.0701007openalex-snapshot
Attenuation of diet‐induced atherosclerosis in rabbits with a highly selective 15‐lipoxygenase inhibitor lacking significant antioxidant properties
inferredcites →https://doi.org/10.1042/bj20021085openalex-snapshot
Small ubiquitin-related modifier-1 (SUMO-1) modification of the glucocorticoid receptor
inferredcites →https://doi.org/10.1042/bj2590315openalex-snapshot
The eicosanoids and their biochemical mechanisms of action
inferredcites →https://doi.org/10.1046/j.1365-2222.2002.01477.xopenalex-snapshot
Expression and activation of 15‐lipoxygenase pathway in severe asthma: relationship to eosinophilic phenotype and collagen deposition
inferredcites →https://doi.org/10.1046/j.1432-0436.1996.6040203.xopenalex-snapshot
Preadipocyte differentiation blocked by prostaglandin stimulation of prostanoid FP2 receptor in murine 3T3-L1 cells
inferredcites →https://doi.org/10.1053/j.gastro.2004.06.049openalex-snapshot
Activation of PPAR γ and δ by conjugated linoleic acid mediates protection from experimental inflammatory bowel disease
inferredcites →https://doi.org/10.1053/jhep.2001.21145openalex-snapshot
Activation of Retinoic X Receptor and Peroxisome Proliferator-Activated Receptor–γ Inhibits Nitric Oxide and Tumor Necrosis Factor–α Production in Rat Kupffer Cells
inferredcites →https://doi.org/10.1054/clnu.2002.0594openalex-snapshot
Colonic anti-inflammatory mechanisms of conjugated linoleic acid
inferredcites →https://doi.org/10.1056/nejm199704103361506openalex-snapshot
Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases
inferredcites →https://doi.org/10.1056/nejmoa073394openalex-snapshot
Rosiglitazone Evaluated for Cardiovascular Outcomes — An Interim Analysis
inferredcites →https://doi.org/10.1073/pnas.0135855100openalex-snapshot
Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist
inferredcites →https://doi.org/10.1073/pnas.0406142101openalex-snapshot
15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-β-induced suppressor of human gastrointestinal cancers
inferredcites →https://doi.org/10.1073/pnas.0408384102openalex-snapshot
Nitrolinoleic acid: An endogenous peroxisome proliferator-activated receptor γ ligand
inferredcites →https://doi.org/10.1073/pnas.0603235103openalex-snapshot
15-Hydroxyprostaglandin dehydrogenase is an in vivo suppressor of colon tumorigenesis
inferredcites →https://doi.org/10.1073/pnas.0707394104openalex-snapshot
Hematopoietic prostaglandin D 2 synthase controls the onset and resolution of acute inflammation through PGD 2 and 15-deoxyΔ 12–14 PGJ 2
inferredcites →https://doi.org/10.1073/pnas.1031789100openalex-snapshot
PPARγ and PPARδ negatively regulate specific subsets of lipopolysaccharide and IFN-γ target genes in macrophages
inferredcites →https://doi.org/10.1073/pnas.1631086100openalex-snapshot
The 15-lipoxygenase-1 product 13- S -hydroxyoctadecadienoic acid down-regulates PPAR-δ to induce apoptosis in colorectal cancer cells
inferredcites →https://doi.org/10.1073/pnas.241410198openalex-snapshot
Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors
inferredcites →https://doi.org/10.1073/pnas.87.18.6959openalex-snapshot
Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions.
inferredcites →https://doi.org/10.1073/pnas.90.15.7270openalex-snapshot
Transmembrane signaling in human polymorphonuclear neutrophils: 15(S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid modulates receptor agonist-triggered cell activation.
inferredcites →https://doi.org/10.1073/pnas.90.6.2160openalex-snapshot
Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.
inferredcites →https://doi.org/10.1073/pnas.91.15.7355openalex-snapshot
Differential expression and activation of a family of murine peroxisome proliferator-activated receptors.
inferredcites →https://doi.org/10.1073/pnas.91.2.752openalex-snapshot
Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor.
inferredcites →https://doi.org/10.1073/pnas.94.12.6148openalex-snapshot
Discovery of a second 15 S -lipoxygenase in humans
inferredcites →https://doi.org/10.1073/pnas.94.9.4312openalex-snapshot
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ
inferredcites →https://doi.org/10.1073/pnas.95.13.7614openalex-snapshot
Expression of the peroxisome proliferator-activated receptor γ (PPARγ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein
inferredcites →https://doi.org/10.1073/pnas.97.24.13275openalex-snapshot
Prostacyclin-mediated activation of peroxisome proliferator-activated receptor δ in colorectal cancer
inferredcites →https://doi.org/10.1073/pnas.97.26.14145openalex-snapshot
Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1)
inferredcites →https://doi.org/10.1073/pnas.97.8.3919openalex-snapshot
Glucocorticoids repress NF-κB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell
inferredcites →https://doi.org/10.1073/pnas.97.9.4844openalex-snapshot
15-Deoxy-Δ 12,14 -prostaglandin J 2 inhibits multiple steps in the NF-κB signaling pathway
inferredcites →https://doi.org/10.1074/jbc.270.22.12953openalex-snapshot
An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)
inferredcites →https://doi.org/10.1074/jbc.270.41.23975openalex-snapshot
Differential Activation of Peroxisome Proliferator-activated Receptors by Eicosanoids
inferredcites →https://doi.org/10.1074/jbc.271.50.31771openalex-snapshot
Insulin- and Mitogen-activated Protein Kinase-mediated Phosphorylation and Activation of Peroxisome Proliferator-activated Receptor γ
inferredcites →https://doi.org/10.1074/jbc.272.16.10811openalex-snapshot
Regulation of Peroxisome Proliferator-activated Receptor γ Activity by Mitogen-activated Protein Kinase
inferredcites →https://doi.org/10.1074/jbc.272.32.20108openalex-snapshot
Polarity and Specific Sequence Requirements of Peroxisome Proliferator-activated Receptor (PPAR)/Retinoid X Receptor Heterodimer Binding to DNA
inferredcites →https://doi.org/10.1074/jbc.272.32.20230openalex-snapshot
Ligand-independent Activation Domain in the N Terminus of Peroxisome Proliferator-activated Receptor γ (PPARγ)
inferredcites →https://doi.org/10.1074/jbc.272.8.5128openalex-snapshot
Transcriptional Activation by Peroxisome Proliferator-activated Receptor γ Is Inhibited by Phosphorylation at a Consensus Mitogen-activated Protein Kinase Site
inferredcites →https://doi.org/10.1074/jbc.273.12.6689openalex-snapshot
Mechanism of Prostaglandin E2 Transport across the Plasma Membrane of HeLa Cells and Xenopus Oocytes Expressing the Prostaglandin Transporter “PGT”
inferredcites →https://doi.org/10.1074/jbc.273.4.1855openalex-snapshot
Prostaglandins Promote and Block Adipogenesis through Opposing Effects on Peroxisome Proliferator-activated Receptor γ
inferredcites →https://doi.org/10.1074/jbc.274.12.7681openalex-snapshot
p300 Interacts with the N- and C-terminal Part of PPARγ2 in a Ligand-independent and -dependent Manner, Respectively
inferredcites →https://doi.org/10.1074/jbc.274.45.32048openalex-snapshot
Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1
inferredcites →https://doi.org/10.1074/jbc.275.2.1287openalex-snapshot
Identification of Amino Acid Determinants of the Positional Specificity of Mouse 8S-Lipoxygenase and Human 15S-Lipoxygenase-2
inferredcites →https://doi.org/10.1074/jbc.c000517200openalex-snapshot
Ligand type-specific Interactions of Peroxisome Proliferator-activated Receptor γ with Transcriptional Coactivators
inferredcites →https://doi.org/10.1074/jbc.m001297200openalex-snapshot
Degradation of the Peroxisome Proliferator-activated Receptor γ Is Linked to Ligand-dependent Activation
inferredcites →https://doi.org/10.1074/jbc.m002577200openalex-snapshot
Oxidized Low Density Lipoprotein Inhibits Interleukin-12 Production in Lipopolysaccharide-activated Mouse Macrophages via Direct Interactions between Peroxisome Proliferator-activated Receptor-γ and Nuclear Factor-κB
inferredcites →https://doi.org/10.1074/jbc.m004045200openalex-snapshot
Induction of IκBα Expression as a Mechanism Contributing to the Anti-inflammatory Activities of Peroxisome Proliferator-activated Receptor-α Activators
inferredcites →https://doi.org/10.1074/jbc.m007237200openalex-snapshot
Peroxisome Proliferator-activated Receptor γ Ligands Suppress the Transcriptional Activation of Cyclooxygenase-2
inferredcites →https://doi.org/10.1074/jbc.m007894200openalex-snapshot
Interferon-γ-induced Regulation of Peroxisome Proliferator-activated Receptor γ and STATs in Adipocytes
inferredcites →https://doi.org/10.1074/jbc.m009404200openalex-snapshot
Core LXXLL Motif Sequences in CREB-binding Protein, SRC1, and RIP140 Define Affinity and Selectivity for Steroid and Retinoid Receptors
inferredcites →https://doi.org/10.1074/jbc.m103241200openalex-snapshot
The Mechanisms by Which Both Heterozygous Peroxisome Proliferator-activated Receptor γ (PPARγ) Deficiency and PPARγ Agonist Improve Insulin Resistance
inferredcites →https://doi.org/10.1074/jbc.m107180200openalex-snapshot
Prostacyclin-dependent Apoptosis Mediated by PPARδ
inferredcites →https://doi.org/10.1074/jbc.m108473200openalex-snapshot
Interferon-γ-mediated Activation and Ubiquitin-Proteasome-dependent Degradation of PPARγ in Adipocytes
inferredcites →https://doi.org/10.1074/jbc.m109.078311openalex-snapshot
SUMOylation of Human Peroxisome Proliferator-activated Receptor α Inhibits Its Trans-activity through the Recruitment of the Nuclear Corepressor NCoR
inferredcites →https://doi.org/10.1074/jbc.m109.085118openalex-snapshot
Leukotriene B4 Is a Physiologically Relevant Endogenous Peroxisome Proliferator-activated Receptor-α Agonist
inferredcites →https://doi.org/10.1074/jbc.m109.091512openalex-snapshot
Covalent Peroxisome Proliferator-activated Receptor γ Adduction by Nitro-fatty Acids
inferredcites →https://doi.org/10.1074/jbc.m110314200openalex-snapshot
15-Deoxy-Δ12,14-prostaglandin J2
inferredcites →https://doi.org/10.1074/jbc.m110598200openalex-snapshot
Peroxisome Proliferator-activated Receptor α (PPARα) Turnover by the Ubiquitin-Proteasome System Controls the Ligand-induced Expression Level of Its Target Genes
inferredcites →https://doi.org/10.1074/jbc.m205738200openalex-snapshot
Selective Interleukin-12 Synthesis Defect in 12/15-Lipoxygenase-deficient Macrophages Associated with Reduced Atherosclerosis in a Mouse Model of Familial Hypercholesterolemia
inferredcites →https://doi.org/10.1074/jbc.m206950200openalex-snapshot
Genetic Analysis of Adipogenesis through Peroxisome Proliferator-activated Receptor γ Isoforms
inferredcites →https://doi.org/10.1074/jbc.m210062200openalex-snapshot
Adipocyte-specific Gene Expression and Adipogenic Steatosis in the Mouse Liver Due to Peroxisome Proliferator-activated Receptor γ1 (PPARγ1) Overexpression
inferredcites →https://doi.org/10.1074/jbc.m403866200openalex-snapshot
Transcriptional Activity of Peroxisome Proliferator-activated Receptor γ Is Modulated by SUMO-1 Modification
inferredcites →https://doi.org/10.1074/jbc.m409468200openalex-snapshot
The Nuclear Receptor Corepressors NCoR and SMRT Decrease Peroxisome Proliferator-activated Receptor γ Transcriptional Activity and Repress 3T3-L1 Adipogenesis
inferredcites →https://doi.org/10.1074/jbc.m500901200openalex-snapshot
α,β-Unsaturated Ketone Is a Core Moiety of Natural Ligands for Covalent Binding to Peroxisome Proliferator-activated Receptor γ
inferredcites →https://doi.org/10.1074/jbc.m504212200openalex-snapshot
Fatty Acid Transduction of Nitric Oxide Signaling
inferredcites →https://doi.org/10.1074/jbc.m508159200openalex-snapshot
Conjugated Linoleic Acid Promotes Human Adipocyte Insulin Resistance through NFκB-dependent Cytokine Production
inferredcites →https://doi.org/10.1074/jbc.m702289200openalex-snapshot
Identification of a Novel Prostaglandin Reductase Reveals the Involvement of Prostaglandin E2 Catabolism in Regulation of Peroxisome Proliferator-activated Receptor γ Activation
inferredcites →https://doi.org/10.1074/jbc.m704085200openalex-snapshot
Nitro-fatty Acid Reaction with Glutathione and Cysteine
inferredcites →https://doi.org/10.1083/jcb.150.5.1199openalex-snapshot
Glucocorticoids Antagonize Ap-1 by Inhibiting the Activation/Phosphorylation of Jnk without Affecting Its Subcellular Distribution
inferredcites →https://doi.org/10.1084/jem.179.6.1903openalex-snapshot
Involvement of 15-lipoxygenase in early stages of atherogenesis.
inferredcites →https://doi.org/10.1084/jem.193.7.827openalex-snapshot
Attenuation of Colon Inflammation through Activators of the Retinoid X Receptor (Rxr)/Peroxisome Proliferator–Activated Receptor γ (Pparγ) Heterodimer
inferredcites →https://doi.org/10.1084/jem.20031619openalex-snapshot
Lysophosphatidic Acid Induces Neointima Formation Through PPARγ Activation
inferredcites →https://doi.org/10.1093/carcin/bgh277openalex-snapshot
NAD+-linked 15-hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer
inferredcites →https://doi.org/10.1093/emboj/17.2.507openalex-snapshot
The coactivator TIF2 contains three nuclear receptor‐binding motifs and mediates transactivation through CBP binding‐dependent and ‐independent pathways
inferredcites →https://doi.org/10.1093/emboj/18.13.3676openalex-snapshot
An adipogenic cofactor bound by the differentiation domain of PPARγ
inferredcites →https://doi.org/10.1093/jn/138.7.1336openalex-snapshot
Cis-9, trans-11-Conjugated Linoleic Acid Inhibits Allergic Sensitization and Airway Inflammation via a PPAR γ-Related Mechanism in Mice3
inferredcites →https://doi.org/10.1097/00005344-199905000-00018openalex-snapshot
PPARγ-Ligands Inhibit Migration Mediated by Multiple Chemoattractants in Vascular Smooth Muscle Cells
inferredcites →https://doi.org/10.1097/01.shk.0000167108.88376.f2openalex-snapshot
15-DEOXY-??12,14-PROSTAGLANDIN J2 (15D-PGJ2), A PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ?? LIGAND, REDUCES TISSUE LEUKOSEQUESTRATION AND MORTALITY IN ENDOTOXIC SHOCK
inferredcites →https://doi.org/10.1101/gad.11.24.3351openalex-snapshot
Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway
inferredcites →https://doi.org/10.1101/gad.1263305openalex-snapshot
Corepressors selectively control the transcriptional activity of PPARγ in adipocytes
inferredcites →https://doi.org/10.1101/gad.14.2.121openalex-snapshot
The coregulator exchange in transcriptional functions of nuclear receptors
inferredcites →https://doi.org/10.1101/gad.1709008openalex-snapshot
PPARγ and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale
inferredcites →https://doi.org/10.1101/gad.501108openalex-snapshot
Genome-wide profiling of PPARγ:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis
showing the first 200 of 275 · page through all 275
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4668629openalex-extracted
Metabolic, Neurotoxic and Immunotoxic Effects of Pfaas and Their Mixtures on the Proteome of the Head Kidney and Plasma from Rainbow Trout
inferred← citeshttps://doi.org/10.2139/ssrn.4782907openalex-extracted
Comparative Molecular Simulation of Pparg Protein Interactions with Omega-3 and Omega-6 Lipid Mediators
inferred← citeshttps://doi.org/10.1002/9783527692156.ch35openalex-snapshot
Inflammation, Hormones, and Metabolism
inferred← citeshttps://doi.org/10.1002/advs.202204190openalex-snapshot
PPARγ Acetylation Orchestrates Adipose Plasticity and Metabolic Rhythms
inferred← citeshttps://doi.org/10.1002/bkcs.10662openalex-snapshot
A Novel Partial PPARα /γ Dual Agonist SN159 Improves Insulin Sensitivity
inferred← citeshttps://doi.org/10.1002/cmdc.201600554openalex-snapshot
Design, Synthesis, and Structure–Activity Relationships of Bavachinin Analogues as Peroxisome Proliferator‐Activated Receptor γ Agonists
inferred← citeshttps://doi.org/10.1002/cti2.70091openalex-snapshot
Fatty acid metabolism—an emerging regulatory node in T‐cell immunometabolism
inferred← citeshttps://doi.org/10.1002/hep.28000openalex-snapshot
Stimulation of nuclear receptor peroxisome proliferator–activated receptor‐γ limits NF‐κB‐dependent inflammation in mouse cystic fibrosis biliary epithelium
inferred← citeshttps://doi.org/10.1002/jlb.3mr0118-034ropenalex-snapshot
PPAR-γ in innate and adaptive lung immunity
inferred← citeshttps://doi.org/10.1002/sctm.17-0098openalex-snapshot
Microparticles Carrying Peroxisome Proliferator-Activated Receptor Alpha Restore the Reduced Differentiation and Functionality of Bone Marrow-Derived Cells Induced by High-Fat Diet
inferred← citeshttps://doi.org/10.1007/978-1-0716-2624-5_1openalex-snapshot
Protein–Metabolite Interactions Shape Cellular Metabolism and Physiology
inferred← citeshttps://doi.org/10.1007/s00421-016-3414-yopenalex-snapshot
Moderate-intensity exercise alters markers of alternative activation in circulating monocytes in females: a putative role for PPARγ
inferred← citeshttps://doi.org/10.1007/s10157-024-02504-8openalex-snapshot
Neferine alleviates acute kidney injury by regulating the PPAR-α/NF-κB pathway
inferred← citeshttps://doi.org/10.1007/s10753-016-0358-7openalex-snapshot
Gamma-Linolenic Acid Suppresses NF-κΒ Signaling via CD36 in the Lipopolysaccharide-Induced Inflammatory Response in Primary Goat Mammary Gland Epithelial Cells
inferred← citeshttps://doi.org/10.1007/s10753-023-01904-4openalex-snapshot
Musclin Mitigates the Attachment of HUVECs to THP-1 Monocytes in Hyperlipidemic Conditions through PPARα/HO-1-Mediated Attenuation of Inflammation
inferred← citeshttps://doi.org/10.1007/s10787-026-02413-0openalex-snapshot
Rewiring the psoriasis–metabolism axis: therapeutic potential of saroglitazar beyond PPAR modulation
inferred← citeshttps://doi.org/10.1007/s12291-023-01166-9openalex-snapshot
Metabolic Reprogramming of Anti-cancer T Cells: Targeting AMPK and PPAR to Optimize Cancer Immunotherapy
inferred← citeshttps://doi.org/10.1007/s12672-026-04972-8openalex-snapshot
Genetic influence of PPAR-γ rs1801282 and MTRR rs162036 variants on non-small cell lung cancer risk in Egyptians
inferred← citeshttps://doi.org/10.1016/b978-0-12-404717-4.00005-6openalex-snapshot
Eicosanoids in Metabolic Syndrome
inferred← citeshttps://doi.org/10.1016/b978-0-444-64057-4.00011-9openalex-snapshot
Natural Bioactive Molecules With Antidiabetic Attributes: Insights Into Structure–Activity Relationships
inferred← citeshttps://doi.org/10.1016/j.apsb.2024.03.030openalex-snapshot
Fenofibrate-promoted hepatomegaly and liver regeneration are PPARα-dependent and partially related to the YAP pathway
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2015.03.042openalex-snapshot
FABP4 inhibition suppresses PPARγ activity and VLDL-induced foam cell formation in IL-4-polarized human macrophages
inferred← citeshttps://doi.org/10.1016/j.bbadis.2014.07.016openalex-snapshot
The arachidonic acid–LTB4–BLT2 pathway enhances human B-CLL aggressiveness
inferred← citeshttps://doi.org/10.1016/j.bbadis.2018.04.024openalex-snapshot
Animal models of NAFLD from the pathologist's point of view
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2018.12.009openalex-snapshot
Epigenetic regulation of carnitine palmitoyltransferase 1 (Cpt1a) by high fat diet
inferred← citeshttps://doi.org/10.1016/j.bbalip.2013.11.012openalex-snapshot
Role of PPAR, LXR, and PXR in epidermal homeostasis and inflammation
inferred← citeshttps://doi.org/10.1016/j.bbalip.2022.159162openalex-snapshot
Peroxisome proliferator-activated receptor gamma is essential for stress adaptation by maintaining lipid homeostasis in female fish
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2025.09.001openalex-snapshot
Bone matrix-mimetic multi-ion doped hydroxyapatite nanorod arrays for enhanced immuno-osteogenesis and prevention of aseptic loosening
inferred← citeshttps://doi.org/10.1016/j.biocel.2016.10.018openalex-snapshot
PPARγ agonists induce adipocyte differentiation by modulating the expression of Lipin-1, which acts as a PPARγ phosphatase
inferred← citeshttps://doi.org/10.1016/j.biopha.2026.119842openalex-snapshot
MHY5535, a novel PPARα antagonist, sensitizes ovarian cancer stem cells to chemotherapy by disrupting fatty acid oxidation-dependent mitochondrial metabolism
inferred← citeshttps://doi.org/10.1016/j.bmc.2013.01.029openalex-snapshot
Thiazolidine-2,4-diones: Progress towards multifarious applications
inferred← citeshttps://doi.org/10.1016/j.bmc.2021.116564openalex-snapshot
Galangin 3-benzyl-5-methylether derivatives function as an adiponectin synthesis-promoting peroxisome proliferator-activated receptor γ partial agonist
inferred← citeshttps://doi.org/10.1016/j.bmc.2025.118245openalex-snapshot
Unveiling the medicinal diversity of benzoic acid containing molecules: Insights on druggable targets for type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.1016/j.bmcl.2012.09.111openalex-snapshot
Synthesis and structure–activity relationships of fibrate-based analogues inside PPARs
inferred← citeshttps://doi.org/10.1016/j.cbi.2017.02.014openalex-snapshot
Antidiabetic effect of SN158 through PPARα/γ dual activation in ob/ob mice
inferred← citeshttps://doi.org/10.1016/j.cell.2024.04.048openalex-snapshot
Evolution of diapause in the African turquoise killifish by remodeling the ancient gene regulatory landscape
inferred← citeshttps://doi.org/10.1016/j.cellsig.2015.09.009openalex-snapshot
Novel phosphorylation of PPARγ ameliorates obesity-induced adipose tissue inflammation and improves insulin sensitivity
inferred← citeshttps://doi.org/10.1016/j.dci.2026.105666openalex-snapshot
PPARγ mediates selenomethionine-induced suppression of NF-κB signaling in bovine endometrial epithelial cells
inferred← citeshttps://doi.org/10.1016/j.diabres.2021.109171openalex-snapshot
Effect of chiglitazar and sitagliptin on glucose variations, insulin resistance and inflammatory-related biomarkers in untreated patients with type 2 diabetes
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2018.09.120openalex-snapshot
Lipid accumulation responses in the liver of Rana nigromaculata induced by perfluorooctanoic acid (PFOA)
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2024.117352openalex-snapshot
Environmental triggers and future risk of developing autoimmune diseases: Molecular mechanism and network toxicology analysis of bisphenol A
inferred← citeshttps://doi.org/10.1016/j.ejmcr.2024.100160openalex-snapshot
Thiazolidinedione an auspicious scaffold as PPAR-γ agonist: its possible mechanism to Manoeuvre against insulin resistant diabetes mellitus
inferred← citeshttps://doi.org/10.1016/j.ejmech.2013.04.026openalex-snapshot
Coumarin chalcone fibrates: A new structural class of lipid lowering agents
inferred← citeshttps://doi.org/10.1016/j.ejmech.2014.10.083openalex-snapshot
Structural development studies of PPARs ligands based on tyrosine scaffold
inferred← citeshttps://doi.org/10.1016/j.ejmech.2015.03.006openalex-snapshot
Synthesis, biological evaluation and molecular modeling studies of the PPARβ/δ antagonist CC618
inferred← citeshttps://doi.org/10.1016/j.ejmech.2022.114240openalex-snapshot
A chemoinformatics search for peroxisome proliferator-activated receptors ligands revealed a new pan-agonist able to reduce lipid accumulation and improve insulin sensitivity
inferred← citeshttps://doi.org/10.1016/j.ejmech.2024.116344openalex-snapshot
Design, synthesis, and biological evaluation of piperazine derivatives as pan-PPARs agonists for the treatment of liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.ejmech.2024.116567openalex-snapshot
A chemical modification of a peroxisome proliferator-activated receptor pan agonist produced a shift to a new dual alpha/gamma partial agonist endowed with mitochondrial pyruvate carrier inhibition and antidiabetic properties
inferred← citeshttps://doi.org/10.1016/j.ejphar.2023.176059openalex-snapshot
IL-33 promotes pancreatic β-cell survival and insulin secretion under diabetogenic conditions through PPARγ
inferred← citeshttps://doi.org/10.1016/j.envpol.2025.126369openalex-snapshot
Perfluorooctanoic acid (PFOA) disrupts cardiac performance of thick-shell mussel by inserting into the binding pocket of proliferator-activated receptor gamma and thereby causing lipid metabolism disorders
inferred← citeshttps://doi.org/10.1016/j.fbio.2026.108661openalex-snapshot
Exploring the potential mechanisms of PFDoA-induced microglial pyroptosis using cell biology experiments, network toxicology and molecular docking
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2014.08.007openalex-snapshot
ROS-dependent Syk and Pyk2-mediated STAT1 activation is required for 15(S)-hydroxyeicosatetraenoic acid-induced CD36 expression and foam cell formation
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2019.04.011openalex-snapshot
Integrated approaches to unravel the impact of protein lipoxidation on macromolecular interactions
inferred← citeshttps://doi.org/10.1016/j.hazadv.2026.101545openalex-snapshot
A critical review of the direct binding of PPARβ/δ with endocrine disrupting chemicals
inferred← citeshttps://doi.org/10.1016/j.imlet.2020.01.006openalex-snapshot
Targeting PPAR ligands as possible approaches for metabolic reprogramming of T cells in cancer immunotherapy
inferred← citeshttps://doi.org/10.1016/j.it.2026.05.006openalex-snapshot
DNA sensing and regulation of lipid metabolism
inferred← citeshttps://doi.org/10.1016/j.jaut.2017.09.007openalex-snapshot
Impaired anti-inflammatory activity of PPARγ in the salivary epithelia of Sjögren's syndrome patients imposed by intrinsic NF-κB activation
inferred← citeshttps://doi.org/10.1016/j.jep.2020.112859openalex-snapshot
Identification of the active compounds and drug targets of Chinese medicine in heart failure based on the PPARs-RXRα pathway
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2026.141479openalex-snapshot
Congener-resolved hazard identification of ginkgolic acids as emerging natural contaminants
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2012.07.010openalex-snapshot
Dietary abscisic acid ameliorates influenza-virus-associated disease and pulmonary immunopathology through a PPARγ-dependent mechanism
inferred← citeshttps://doi.org/10.1016/j.jsb.2015.07.006openalex-snapshot
Different binding and recognition modes of GL479, a dual agonist of Peroxisome Proliferator-Activated Receptor α/γ
inferred← citeshttps://doi.org/10.1016/j.matdes.2023.112412openalex-snapshot
Clickable corneal neovascularization therapy with ROS-responsive polydopamine silica nanoparticles loaded with fenofibrate
inferred← citeshttps://doi.org/10.1016/j.mce.2017.07.037openalex-snapshot
Differentially expressed genes in PPARγ-deficient MSCs
inferred← citeshttps://doi.org/10.1016/j.mce.2021.111312openalex-snapshot
Retinol-binding protein 4 in obesity and metabolic dysfunctions
inferred← citeshttps://doi.org/10.1016/j.metabol.2013.07.002openalex-snapshot
Dynamics of serum metabolites in patients with chronic hepatitis C receiving pegylated interferon plus ribavirin: A metabolomics analysis
inferred← citeshttps://doi.org/10.1016/j.molmed.2012.03.004openalex-snapshot
PPARγ as a therapeutic target in cystic fibrosis
inferred← citeshttps://doi.org/10.1016/j.phrs.2016.10.014openalex-snapshot
Upregulation of MKP-7 in response to rosiglitazone treatment ameliorates lipopolysaccharide-induced destabilization of SIRT1 by inactivating JNK
inferred← citeshttps://doi.org/10.1016/j.plipres.2017.04.003openalex-snapshot
Prostaglandin synthases: Molecular characterization and involvement in prostaglandin biosynthesis
inferred← citeshttps://doi.org/10.1016/j.prenap.2026.100603openalex-snapshot
Phytochemicals and PPAR activation: Unlocking natural solutions for neurodegenerative diseases
inferred← citeshttps://doi.org/10.1016/j.prostaglandins.2025.107053openalex-snapshot
Signaling pathways shaping the field of lipidomics
inferred← citeshttps://doi.org/10.1016/j.reprotox.2026.109368openalex-snapshot
Integrative network toxicology and experimental validation define mechanisms of perfluorodecanoic acid (PFDA) induced granulosa cell toxicity and attenuation by kaempferol in HGrC1 cells
inferred← citeshttps://doi.org/10.1016/j.sciaf.2026.e03678openalex-snapshot
Integrated computational analysis of Phoenix dactylifera and Ficus carica reveals therapeutic networks and gut-related pathways associated with obesity and gastrointestinal disorders
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2024.172389openalex-snapshot
Metabolic, neurotoxic and immunotoxic effects of PFAAs and their mixtures on the proteome of the head kidney and plasma from rainbow trout (Oncorhynchus mykiss)
inferred← citeshttps://doi.org/10.1016/j.semcdb.2017.10.012openalex-snapshot
Milk lipid regulation at the maternal-offspring interface
inferred← citeshttps://doi.org/10.1016/j.toxlet.2021.12.001openalex-snapshot
Sunscreen filter octocrylene is a potential obesogen by acting as a PPARγ partial agonist
inferred← citeshttps://doi.org/10.1016/j.tube.2019.04.016openalex-snapshot
Mycobacterium tuberculosis and macrophage nuclear receptors: What we do and don't know
inferred← citeshttps://doi.org/10.1021/acs.jcim.3c00033openalex-snapshot
Computational Prediction of the Phenotypic Effect of Flavonoids on Adiponectin Biosynthesis
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.0c01874openalex-snapshot
Discovery and Structure–Activity Relationships of Novel Template, Truncated 1′-Homologated Adenosine Derivatives as Pure Dual PPARγ/δ Modulators
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.2c02093openalex-snapshot
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.2c00791openalex-snapshot
Discovery of Pan-peroxisome Proliferator-Activated Receptor Modulators from an Endolichenic Fungus, Daldinia childiae
inferred← citeshttps://doi.org/10.1021/acschembio.3c00194openalex-snapshot
CES1 Releases Oxylipins from Oxidized Triacylglycerol (oxTAG) and Regulates Macrophage oxTAG/TAG Accumulation and PGE2/IL-1β Production
inferred← citeshttps://doi.org/10.1021/acsmedchemlett.2c00511openalex-snapshot
Prenylated Chrysin Derivatives as Partial PPARγ Agonists with Adiponectin Secretion-Inducing Activity
inferred← citeshttps://doi.org/10.1021/ci500729kopenalex-snapshot
Mapping Functional Group Free Energy Patterns at Protein Occluded Sites: Nuclear Receptors and G-Protein Coupled Receptors
inferred← citeshttps://doi.org/10.1021/cr500504wopenalex-snapshot
Synthesis of Chiral Cyclopentenones
inferred← citeshttps://doi.org/10.1021/pr400026qopenalex-snapshot
NMR Metabolomics Analysis of the Effects of 5-Lipoxygenase Inhibitors on Metabolism in Glioblastomas
inferred← citeshttps://doi.org/10.1038/leu.2012.329openalex-snapshot
PPAR-alpha is a therapeutic target for chronic lymphocytic leukemia
inferred← citeshttps://doi.org/10.1038/leu.2016.395openalex-snapshot
PPAR-delta promotes survival of chronic lymphocytic leukemia cells in energetically unfavorable conditions
inferred← citeshttps://doi.org/10.1038/leu.2017.162openalex-snapshot
PPAR-delta modulates membrane cholesterol and cytokine signaling in malignant B cells
inferred← citeshttps://doi.org/10.1038/nm.3159openalex-snapshot
PPARγ signaling and metabolism: the good, the bad and the future
inferred← citeshttps://doi.org/10.1038/oncsis.2016.41openalex-snapshot
PPAR-delta promotes survival of breast cancer cells in harsh metabolic conditions
inferred← citeshttps://doi.org/10.1038/s41388-025-03492-zopenalex-snapshot
PPARγ acetylation governs mammary adenocarcinoma tumor growth via acetylated residues that determine DNA sequence-specific binding
inferred← citeshttps://doi.org/10.1038/s41467-026-69250-1openalex-snapshot
Hepatocytes functionally reprogrammed by KIAA1199-high colorectal cancer cells favour the accumulation of pro-metastatic Egr1+ neutrophils
inferred← citeshttps://doi.org/10.1038/s41536-022-00246-3openalex-snapshot
Harnessing conserved signaling and metabolic pathways to enhance the maturation of functional engineered tissues
inferred← citeshttps://doi.org/10.1038/s41540-017-0032-1openalex-snapshot
Deconstructing the traditional Japanese medicine “Kampo”: compounds, metabolites and pharmacological profile of maoto, a remedy for flu-like symptoms
inferred← citeshttps://doi.org/10.1038/s41598-019-47057-zopenalex-snapshot
Neuroprotective effects of oleic acid in rodent models of cerebral ischaemia
inferred← citeshttps://doi.org/10.1038/s41598-025-20731-1openalex-snapshot
Fenofibrate differentially activates PPARα-mediated lipid metabolism in rat kidney and liver
inferred← citeshttps://doi.org/10.1038/s44321-025-00216-4openalex-snapshot
Identification of PTGR2 inhibitors as a new therapeutic strategy for diabetes and obesity
inferred← citeshttps://doi.org/10.1038/srep34792openalex-snapshot
Structural basis for PPAR partial or full activation revealed by a novel ligand binding mode
inferred← citeshttps://doi.org/10.1074/jbc.m115.686865openalex-snapshot
Reactive Oxygen Species (ROS) Mediate p300-dependent STAT1 Protein Interaction with Peroxisome Proliferator-activated Receptor (PPAR)-γ in CD36 Protein Expression and Foam Cell Formation
inferred← citeshttps://doi.org/10.1074/jbc.m116.751909openalex-snapshot
Identification of a novel series of anti-inflammatory and anti-oxidative phospholipid oxidation products containing the cyclopentenone moiety in vitro and in vivo: Implication in atherosclerosis
inferred← citeshttps://doi.org/10.1080/01616412.2024.2325313openalex-snapshot
Propane-2-sulfonic acid octadec-9-enyl-amide, a novel PPARα/γ dual agonist, attenuates molecular pathological alterations in learning memory in AD mice
inferred← citeshttps://doi.org/10.1080/10408398.2023.2203753openalex-snapshot
Nervonic acid and its sphingolipids: Biological functions and potential food applications
inferred← citeshttps://doi.org/10.1080/10408398.2024.2313181openalex-snapshot
Omega-9 monounsaturated fatty acids: a review of current scientific evidence of sources, metabolism, benefits, recommended intake, and edible safety
inferred← citeshttps://doi.org/10.1080/87559129.2026.2711909openalex-snapshot
Research Progress on the Mechanisms Underlying the Amelioration of Alcoholic Liver Disease by Major Functional Components of Ginseng
inferred← citeshttps://doi.org/10.1093/braincomms/fcaa145openalex-snapshot
A potential role of fatty acid binding protein 4 in the pathophysiology of autism spectrum disorder
inferred← citeshttps://doi.org/10.1093/jleuko/qiae170openalex-snapshot
Unlocking secrets: lipid metabolism and lipid droplet crucial roles in SARS-CoV-2 infection and the immune response
inferred← citeshttps://doi.org/10.1093/med/9780197501207.003.0023openalex-snapshot
Ketogenic Diet and PPARγ
inferred← citeshttps://doi.org/10.1093/milmed/usaf622openalex-snapshot
Oxylipin Responses during the Yukon Arctic Ultra: The Longest and Coldest Ultramarathon in the World
inferred← citeshttps://doi.org/10.1096/fj.202000467ropenalex-snapshot
Thymopentin improves the survival of septic mice by promoting the production of 15‐deoxy‐prostaglandin J2 and activating the PPARγ signaling pathway
inferred← citeshttps://doi.org/10.1101/2021.08.18.456879openalex-snapshot
Identifying Therapeutic Strategies in IgA Nephropathy through Comprehensive Transcriptomic Characterization
inferred← citeshttps://doi.org/10.1101/2024.09.13.608378openalex-snapshot
Qing-Luo-Yin-induced SIRT1 inhibition contributes to the immune improvement of adjuvant-induced arthritis rats
inferred← citeshttps://doi.org/10.1101/2024.12.17.629058openalex-snapshot
Identification of PTGR2 inhibitors as a new therapy for diabetes and obesity
inferred← citeshttps://doi.org/10.1111/all.14295openalex-snapshot
Current perspective on eicosanoids in asthma and allergic diseases: EAACI Task Force consensus report, part I
inferred← citeshttps://doi.org/10.1111/febs.14043openalex-snapshot
Cysteine proteases in atherosclerosis
inferred← citeshttps://doi.org/10.1111/sji.70061openalex-snapshot
The Nuclear Receptor Nurr1 Modulates the Expression and Activity of PPARγ in Human Pro‐Inflammatory Macrophages
inferred← citeshttps://doi.org/10.11131/2018/101306openalex-snapshot
PPARs: Key Regulators of Airway Inflammation and Potential Therapeutic Targets in Asthma
inferred← citeshttps://doi.org/10.1124/mol.114.094284openalex-snapshot
Robust Hydrolysis of Prostaglandin Glycerol Esters by Human Monoacylglycerol Lipase (MAGL)
inferred← citeshttps://doi.org/10.1124/mol.119.117887openalex-snapshot
The Peroxisome Proliferator–Activated Receptor (PPAR)-γ Antagonist 2-Chloro-5-Nitro-N-Phenylbenzamide (GW9662) Triggers Perilipin 2 Expression via PPARδ and Induces Lipogenesis and Triglyceride Accumulation in Human THP-1 Macrophages
inferred← citeshttps://doi.org/10.1128/mcb.06193-11openalex-snapshot
Retinol-Binding Protein 4 Inhibits Insulin Signaling in Adipocytes by Inducing Proinflammatory Cytokines in Macrophages through a c-Jun N-Terminal Kinase- and Toll-Like Receptor 4-Dependent and Retinol-Independent Mechanism
inferred← citeshttps://doi.org/10.1139/cjpp-2016-0574openalex-snapshot
Protective effects of pioglitazone on vascular endothelial cell dysfunction induced by high glucose via inhibition of IKKα/β–NFκB signaling mediated by PPARγ in vitro
inferred← citeshttps://doi.org/10.1146/annurev-biochem-061516-044445openalex-snapshot
How α-Helical Motifs Form Functionally Diverse Lipid-Binding Compartments
inferred← citeshttps://doi.org/10.1152/ajpendo.00406.2023openalex-snapshot
Larsucosterol: endogenous epigenetic regulator for treating chronic and acute liver diseases
inferred← citeshttps://doi.org/10.1152/ajpregu.00355.2015openalex-snapshot
Adipogenic role of alternatively activated macrophages in β-adrenergic remodeling of white adipose tissue
inferred← citeshttps://doi.org/10.1155/2012/352807openalex-snapshot
Activation of Peroxisome Proliferator-Activated Receptor γ by Rosiglitazone Inhibits Lipopolysaccharide-Induced Release of High Mobility Group Box 1
inferred← citeshttps://doi.org/10.1155/2016/2612743openalex-snapshot
PPAR Ligands Function as Suppressors That Target Biological Actions of HMGB1
inferred← citeshttps://doi.org/10.1155/2016/6517313openalex-snapshot
Peroxisome Proliferator-Activated Receptor Modulation during Metabolic Diseases and Cancers: Master and Minions
inferred← citeshttps://doi.org/10.1155/2020/8906968openalex-snapshot
Peroxisome Proliferator-Activated Receptors as a Therapeutic Target in Asthma
inferred← citeshttps://doi.org/10.1155/2020/9657380openalex-snapshot
The PPARΩPocket: Renewed Opportunities for Drug Development
inferred← citeshttps://doi.org/10.1155/2021/6889533openalex-snapshot
The Role and Mechanism of Oxidative Stress and Nuclear Receptors in the Development of NAFLD
inferred← citeshttps://doi.org/10.1155/2023/8047378openalex-snapshot
Peptide Helix-Y12 as Potential Effector for Peroxisome Proliferator-Activated Receptors
inferred← citeshttps://doi.org/10.1155/ijh/5580454openalex-snapshot
Metabolic‐Associated Steatotic Liver Disease: From Molecular Mechanisms to Novel Therapies
inferred← citeshttps://doi.org/10.1155/ppar/2166122openalex-snapshot
Metabolic Reprogramming and Immune Metabolism in Sepsis: Targeting the PPAR Pathway for Personalized Therapeutic Approaches
inferred← citeshttps://doi.org/10.1158/0008-5472.c.6513441.v1openalex-snapshot
Data from Immune Infiltrate and Tumor Microenvironment Transcriptional Programs Stratify Pediatric Osteosarcoma into Prognostic Groups at Diagnosis
inferred← citeshttps://doi.org/10.1158/0008-5472.can-20-4189openalex-snapshot
Immune Infiltrate and Tumor Microenvironment Transcriptional Programs Stratify Pediatric Osteosarcoma into Prognostic Groups at Diagnosis
inferred← citeshttps://doi.org/10.1158/1541-7786.mcr-19-1223openalex-snapshot
Secreted Factors from Adipose Tissue Reprogram Tumor Lipid Metabolism and Induce Motility by Modulating PPARα/ANGPTL4 and FAK
inferred← citeshttps://doi.org/10.1159/000542578openalex-snapshot
Immunometabolic Targets in CD8+ T Cells within the Tumor Microenvironment of Hepatocellular Carcinoma
inferred← citeshttps://doi.org/10.11606/d.42.2015.tde-07122015-201004openalex-snapshot
Tratamento com metformina restaurou danos metabólicos causados pela obesidade, mas induziu a resposta inflamatória hepática.
inferred← citeshttps://doi.org/10.11606/t.76.2013.tde-31072013-141118openalex-snapshot
Estudos estruturais e funcionais dos receptores ativadores da proliferação de peroxissomos
inferred← citeshttps://doi.org/10.11606/t.76.2014.tde-31072014-171832openalex-snapshot
Caracterização estrutural dos complexos entre os receptores ativadores da proliferação de peroxissomos (PPARs) dos tipos alfa e gama e seus agonistas
inferred← citeshttps://doi.org/10.11606/t.76.2018.tde-29012018-102600openalex-snapshot
Estudos estruturais de novos ligantes sintéticos do receptor PPARY
inferred← citeshttps://doi.org/10.1161/circresaha.115.307730openalex-snapshot
The Ubiquitin-Like SUMO System and Heart Function
inferred← citeshttps://doi.org/10.1161/circresaha.119.315862openalex-snapshot
Cardiomyocyte Maturation
inferred← citeshttps://doi.org/10.1182/blood-2013-03-489468openalex-snapshot
PPARα and fatty acid oxidation mediate glucocorticoid resistance in chronic lymphocytic leukemia
inferred← citeshttps://doi.org/10.1186/s12860-018-0176-xopenalex-snapshot
PIAS1 protects against myocardial ischemia-reperfusion injury by stimulating PPARγ SUMOylation
inferred← citeshttps://doi.org/10.1186/s12944-025-02768-3openalex-snapshot
Imidazole propionate ameliorates lipid metabolism in adipocytes to attenuate high-fat diet-induced obesity via PPAR signaling pathway
inferred← citeshttps://doi.org/10.1186/s40635-017-0128-3openalex-snapshot
Proliferation and differentiation of adipose tissue in prolonged lean and obese critically ill patients
inferred← citeshttps://doi.org/10.1210/er.2018-00064openalex-snapshot
Molecular Actions of PPARα in Lipid Metabolism and Inflammation
inferred← citeshttps://doi.org/10.1371/journal.pone.0302286openalex-snapshot
Effects of eicosapentaneoic acid on innate immune responses in an Atlantic salmon kidney cell line in vitro
inferred← citeshttps://doi.org/10.14341/omet13226openalex-snapshot
«Obesogenic memory» as a neurobiological mechanism predicting the recurrent course of obesity
inferred← citeshttps://doi.org/10.14393/ufu.di.2017.441openalex-snapshot
15-Deoxi-∆12,14-prostaglandina J2 (15d-PGJ2) reduz a produção de IL-8 induzida por alérgenos do ácaro Dermatophagoides pteronyssinus em linhagem de queratinócitos humanos
inferred← citeshttps://doi.org/10.14670/hh-18-322openalex-snapshot
Defective expression of the peroxisome regulators PPARα receptors and lysogenesis with increased cellular senescence in the venous wall of chronic venous disorder.
inferred← citeshttps://doi.org/10.1517/14728222.2012.715633openalex-snapshot
PPARα as a therapeutic target in inflammation-associated diseases
inferred← citeshttps://doi.org/10.15252/emmm.201708237openalex-snapshot
CRTH2 promotes endoplasmic reticulum stress‐induced cardiomyocyte apoptosis through m‐calpain
inferred← citeshttps://doi.org/10.1530/jme-14-0063openalex-snapshot
PPAR ligands improve impaired metabolic pathways in fetal hearts of diabetic rats
inferred← citeshttps://doi.org/10.1536/ihj.24-615openalex-snapshot
Exploring Novel Therapeutics for Pulmonary Arterial Hypertension
inferred← citeshttps://doi.org/10.15761/bgg.1000132openalex-snapshot
SNPs, transcriptional factor binding sites and disease
inferred← citeshttps://doi.org/10.21203/rs.3.rs-10634306/v1openalex-snapshot
Protective effect of somatostatin on the intestinal epithelial glycocalyx in septic rats: A multi-omics screening study
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3137556/v1openalex-snapshot
Identification of PPAR β/δ agonists using a drug-repurposing approach by computational HTVS and molecular docking/ dynamics simulation
inferred← citeshttps://doi.org/10.2147/dddt.s320599openalex-snapshot
Qing-Luo-Yin Alleviated Monocytes/Macrophages-Mediated Inflammation in Rats with Adjuvant-Induced Arthritis by Disrupting Their Interaction with (Pre)-Adipocytes Through PPAR-γ Signaling
inferred← citeshttps://doi.org/10.2147/dddt.s397914openalex-snapshot
α-Mangostin Inhibited M1 Polarization of Macrophages/Monocytes in Antigen-Induced Arthritis Mice by Up-Regulating Silent Information Regulator 1 and Peroxisome Proliferators-Activated Receptor γ Simultaneously
inferred← citeshttps://doi.org/10.2147/jir.s295957openalex-snapshot
Securidaca inappendiculata-Derived Xanthones Protected Joints from Degradation in Male Rats with Collagen-Induced Arthritis by Regulating PPAR-γ Signaling
inferred← citeshttps://doi.org/10.2147/jir.s378090openalex-snapshot
AMPK/SIRT1 Deficiency Drives Adjuvant-Induced Arthritis in Rats by Promoting Glycolysis-Mediated Monocytes Inflammatory Polarization
inferred← citeshttps://doi.org/10.2147/jir.s474329openalex-snapshot
Qing-Luo-Yin Eased Adjuvant-Induced Arthritis by Inhibiting SIRT1-Controlled Visfatin Production in White Adipose Tissues
inferred← citeshttps://doi.org/10.2174/0113892002393801250812063417openalex-snapshot
Mechanism of Tetrandrine in Ameliorating Hypoxic Pulmonary Hypertension Vascular Remodeling through Transcriptomics and Metabolomics
inferred← citeshttps://doi.org/10.2174/1381612827666210622104428openalex-snapshot
Application of Machine Learning Methods for the Development of Antidiabetic Drugs
inferred← citeshttps://doi.org/10.2174/1389557521666210422112740openalex-snapshot
Peroxisome Proliferator-activated Receptor-γ As A Novel and Promising Target For Treating Cancer Via Regulation of Inflammation: A Brief Review
inferred← citeshttps://doi.org/10.2337/db20-1245openalex-snapshot
Topical Aspirin Administration Improves Cutaneous Wound Healing in Diabetic Mice Through a Phenotypic Switch of Wound Macrophages Toward an Anti-inflammatory and Proresolutive Profile Characterized by LXA4 Release
inferred← citeshttps://doi.org/10.2741/4425openalex-snapshot
Nitro-fatty acids in cardiovascular regulation and diseases characteristics and molecular mechanisms
inferred← citeshttps://doi.org/10.32895/ump.mpr.5.4.5openalex-snapshot
Structure-based virtual screening of plant-derived natural compounds as potential PPARα agonists for the treatment of dyslipidemia
inferred← citeshttps://doi.org/10.3389/fcimb.2025.1645333openalex-snapshot
Classification and regulatory interactions of key transcription factors in COVID-19
inferred← citeshttps://doi.org/10.3389/fendo.2026.1744741openalex-snapshot
Protective role of aqueous Coriandrum sativum seed extract in diet-induced glucolipid metabolic disorder through gut–liver axis regulation
inferred← citeshttps://doi.org/10.3389/fimmu.2019.01769openalex-snapshot
Mechanisms Underlying the Functional Cooperation Between PPARα and GRα to Attenuate Inflammatory Responses
inferred← citeshttps://doi.org/10.3389/fimmu.2021.783780openalex-snapshot
Parsing the Role of PPARs in Macrophage Processes
inferred← citeshttps://doi.org/10.3389/fmolb.2020.578964openalex-snapshot
ssRNA Virus and Host Lipid Rearrangements: Is There a Role for Lipid Droplets in SARS-CoV-2 Infection?
inferred← citeshttps://doi.org/10.3389/fphar.2023.1254317openalex-snapshot
A glimpse of the connection between PPARγ and macrophage
inferred← citeshttps://doi.org/10.3389/ftox.2024.1347965openalex-snapshot
Determination of in vitro immunotoxic potencies of a series of perfluoralkylsubstances (PFASs) in human Namalwa B lymphocyte and human Jurkat T lymphocyte cells
inferred← citeshttps://doi.org/10.3390/biom12050723openalex-snapshot
PPARα Signaling: A Candidate Target in Psychiatric Disorder Management
inferred← citeshttps://doi.org/10.3390/biom14060606openalex-snapshot
Activation of Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) in Keratinocytes by Endogenous Fatty Acids
inferred← citeshttps://doi.org/10.3390/biomedicines10112686openalex-snapshot
The Role of CYP3A in Health and Disease
inferred← citeshttps://doi.org/10.3390/cancers13092171openalex-snapshot
Pparγ1 Facilitates ErbB2-Mammary Adenocarcinoma in Mice
inferred← citeshttps://doi.org/10.3390/cells12081116openalex-snapshot
Selective PPAR-Delta/PPAR-Gamma Activation Improves Cognition in a Model of Alzheimer’s Disease
inferred← citeshttps://doi.org/10.3390/cells12151993openalex-snapshot
RXR Agonists Enhance Lenalidomide Anti-Myeloma Activity and T Cell Functions while Retaining Glucose-Lowering Effect
inferred← citeshttps://doi.org/10.3390/cells13201688openalex-snapshot
The Versatile Role of Peroxisome Proliferator-Activated Receptors in Immune-Mediated Intestinal Diseases
inferred← citeshttps://doi.org/10.3390/ijms131216267openalex-snapshot
Lysophosphatidylcholine Acyltransferase 3 Is the Key Enzyme for Incorporating Arachidonic Acid into Glycerophospholipids during Adipocyte Differentiation
inferred← citeshttps://doi.org/10.3390/ijms19113339openalex-snapshot
The Role of PPAR-δ in Metabolism, Inflammation, and Cancer: Many Characters of a Critical Transcription Factor
inferred← citeshttps://doi.org/10.3390/ijms21238893openalex-snapshot
hiPSC-Derived Cardiac Tissue for Disease Modeling and Drug Discovery
inferred← citeshttps://doi.org/10.3390/ijms22147354openalex-snapshot
PPARdelta in Affected Atopic Dermatitis and Psoriasis: A Possible Role in Metabolic Reprograming
inferred← citeshttps://doi.org/10.3390/ijms222212545openalex-snapshot
Priming, Triggering, Adaptation and Senescence (PTAS): A Hypothesis for a Common Damage Mechanism of Steatohepatitis
inferred← citeshttps://doi.org/10.3390/ijms23031645openalex-snapshot
Identifying the Metabolic Signatures of PPARD-Overexpressing Gastric Tumors
inferred← citeshttps://doi.org/10.3390/ijms24065493openalex-snapshot
Metabolic Reprogramming and Potential Therapeutic Targets in Lymphoma
inferred← citeshttps://doi.org/10.3390/ijms26020699openalex-snapshot
Utilization of Cannabidiol in Post-Organ-Transplant Care
inferred← citeshttps://doi.org/10.3390/ijms262110731openalex-snapshot
In Silico Integrated Systems Biology Analysis of Gut-Derived Metabolites from Philippine Medicinal Plants Against Atopic Dermatitis
inferred← citeshttps://doi.org/10.3390/ijms27052224openalex-snapshot
EV-Encapsulated Mitochondrial miRNAs: Enhancing Cardiomyocyte Bioenergetics
inferred← citeshttps://doi.org/10.3390/ijms27062842openalex-snapshot
7-Ketocholesterol Links Sterol Homeostasis to Hedgehog Signaling and Stress–Survival Responses in MSCs from Patients with Acute Myeloid Leukemia
inferred← citeshttps://doi.org/10.3390/life16081359openalex-snapshot
Integrated Phytochemical, Network Pharmacology, and Molecular Docking Analyses of Triphala Extract Reveal Protective Effects Against H2O2-Induced Oxidative Hemolysis in G6PD-Deficient Erythrocytes
inferred← citeshttps://doi.org/10.3390/lipidology3010006openalex-snapshot
Lipids and Their Role in Aging and Neurodegenerative Decline
inferred← citeshttps://doi.org/10.3390/metabo16030201openalex-snapshot
Dietary Citrus Peel Supplementation Enhances Hepatic Energy Metabolism, Muscle 9-HODE Generation and Isoleucine Catabolism in Beef Cattle
inferred← citeshttps://doi.org/10.3390/microorganisms12101995openalex-snapshot
Ionizing Radiation Dose Differentially Affects the Host–Microbe Relationship over Time
inferred← citeshttps://doi.org/10.3390/s23031338openalex-snapshot
A Multiplex Molecular Cell-Based Sensor to Detect Ligands of PPARs: An Optimized Tool for Drug Discovery in Cyanobacteria
inferred← citeshttps://doi.org/10.3892/mmr.2012.785openalex-snapshot
Gene expression of adipose tissue, endothelial cells and platelets in subjects with metabolic syndrome (Review)
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