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Medicinal Chemistry of Combretastatin A4: Present and Future Directions
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inferredcites →https://doi.org/10.1002/(sici)1098-1128(199807)18:4<259::aid-med3>3.0.co;2-uopenalex-snapshot
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inferredcites →https://doi.org/10.1002/ijc.20297openalex-snapshot
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inferredcites →https://doi.org/10.1007/bf01954881openalex-snapshot
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inferredcites →https://doi.org/10.1016/0968-0896(96)00158-7openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.bmc.2005.02.039openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.bmc.2005.06.028openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.bmcl.2003.07.003openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.bmcl.2004.02.050openalex-snapshot
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inferredcites →https://doi.org/10.1021/jm970644qopenalex-snapshot
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inferredcites →https://doi.org/10.1021/jm9807149openalex-snapshot
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inferredcites →https://doi.org/10.1038/nature03794openalex-snapshot
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inferredcites →https://doi.org/10.1039/b505955kopenalex-snapshot
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inferredcites →https://doi.org/10.1080/14756360412331280473openalex-snapshot
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inferredcites →https://doi.org/10.1097/00001813-199903000-00010openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/chin.200634264openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/cmdc.201100121openalex-snapshot
Novel 2‐Substituted Quinolin‐4‐yl‐benzenesulfonate Derivatives: Synthesis, Antiproliferative Activity, and Inhibition of Cellular Tubulin Polymerization
inferred← citeshttps://doi.org/10.1002/cmdc.201100154openalex-snapshot
Synthesis and Structure–Activity Relationships of Constrained Heterocyclic Analogues of Combretastatin A4
inferred← citeshttps://doi.org/10.1002/cmdc.201100193openalex-snapshot
The Metabolic Fate of isoCombretastatin A‐4 in Human Liver Microsomes: Identification, Synthesis and Biological Evaluation of Metabolites
inferred← citeshttps://doi.org/10.1002/cmdc.201100279openalex-snapshot
Synthesis and Antitumor Molecular Mechanism of Agents Based on Amino 2‐(3′,4′,5′‐Trimethoxybenzoyl)benzo[b]furan: Inhibition of Tubulin and Induction of Apoptosis
inferred← citeshttps://doi.org/10.1002/cmdc.201100361openalex-snapshot
The Tubulin Colchicine Domain: a Molecular Modeling Perspective
inferred← citeshttps://doi.org/10.1002/cmdc.201100511openalex-snapshot
3‐Substituted 2‐Phenylimidazo[2,1‐b]benzothiazoles: Synthesis, Anticancer Activity, and Inhibition of Tubulin Polymerization
inferred← citeshttps://doi.org/10.1002/cmdc.201200561openalex-snapshot
A Concise Synthesis of Pyrazole Analogues of Combretastatin A1 as Potent Anti‐Tubulin Agents
inferred← citeshttps://doi.org/10.1002/cmdc.201300531openalex-snapshot
Effects of the Tumor‐Vasculature‐Disrupting Agent Verubulin and Two Heteroaryl Analogues on Cancer Cells, Endothelial Cells, and Blood Vessels
inferred← citeshttps://doi.org/10.1002/cmdc.201400049openalex-snapshot
Gold(I) Biscarbene Complexes Derived from Vascular‐Disrupting Combretastatin A‐4 Address Different Targets and Show Antimetastatic Potential
inferred← citeshttps://doi.org/10.1002/cmdc.201500069openalex-snapshot
Iso CombretaQuinazolines: Potent Cytotoxic Agents with Antitubulin Activity
inferred← citeshttps://doi.org/10.1002/cmdc.201700045openalex-snapshot
Anticancer Activity of Stilbene‐Based Derivatives
inferred← citeshttps://doi.org/10.1002/cmdc.201800567openalex-snapshot
Evaluation of Sydnone‐Based Analogues of Combretastatin A‐4 Phosphate (CA4P) as Vascular Disrupting Agents for Use in Cancer Therapy
inferred← citeshttps://doi.org/10.1002/cmdc.201800641openalex-snapshot
Synthesis, Biological Evaluation, and Molecular Docking of Combretastatin and Colchicine Derivatives and their hCE1‐Activated Prodrugs as Antiviral Agents
inferred← citeshttps://doi.org/10.1002/cmdc.202000197openalex-snapshot
Synthesis and Anticancer Properties of Oxazepines Related to Azaisoerianin and IsoCoQuines
inferred← citeshttps://doi.org/10.1002/cmdc.202100706openalex-snapshot
Styryl Group, a Friend or Foe in Medicinal Chemistry
inferred← citeshttps://doi.org/10.1002/cmdc.202300081openalex-snapshot
Hybridization of the Pharmacophoric Features of Discoipyrrole C and Combretastatin A‐4 toward New Anticancer Leads
inferred← citeshttps://doi.org/10.1002/cpz1.70232openalex-snapshot
Design and Analysis of Untargeted Metabolomics Experiments
inferred← citeshttps://doi.org/10.1002/ejoc.200800738openalex-snapshot
Regioselective Synthesis of 4,5‐Diaryl‐1‐methyl‐1H‐imidazoles Including Highly Cytotoxic Derivatives by Pd‐Catalyzed Direct C‐5 Arylation of 1‐Methyl‐1H‐imidazole with Aryl Bromides
inferred← citeshttps://doi.org/10.1002/ejoc.200800957openalex-snapshot
A Novel Approach to Combretastatins: From trans‐Epoxide to CA‐4 and Its Dioxolane Derivative
inferred← citeshttps://doi.org/10.1002/ejoc.200900581openalex-snapshot
An Economical Access to 3,4‐Diaryl‐2(5H)‐furanones and 4‐Aryl‐6‐methyl‐2(2H)‐pyranones by Pd‐Catalyzed Suzuki‐Type Arylation of 3‐Aryl‐4‐tosyloxy‐2(5H)‐furanones and 6‐Methyl‐4‐tosyloxy‐2(2H)‐pyranones, Respectively
inferred← citeshttps://doi.org/10.1002/ejoc.201000393openalex-snapshot
Iron‐Catalyzed Cross‐Coupling between 1‐Bromoalkynes and Grignard‐Derived Organocuprate Reagents
inferred← citeshttps://doi.org/10.1002/ejoc.201000532openalex-snapshot
Weinreb Amide Based Building Blocks for Convenient Access to Analogues of Phenstatin
inferred← citeshttps://doi.org/10.1002/ejoc.201301725openalex-snapshot
Design and Synthesis of Pironetin Analogue/Combretastatin A‐4 Hybrids and Evaluation of Their Cytotoxic Activity
inferred← citeshttps://doi.org/10.1002/ejoc.201402850openalex-snapshot
Synthesis of Indole‐Derived Allocolchicine Congeners through Pd‐Catalyzed Intramolecular C‐H Arylation Reaction
inferred← citeshttps://doi.org/10.1002/ejoc.201601069openalex-snapshot
Synthesis of Nonracemic Pyrrolo‐allocolchicinoids Exhibiting Potent Cytotoxic Activity
inferred← citeshttps://doi.org/10.1002/ejoc.201800583openalex-snapshot
Mixed AuPd Nanoparticles as Highly Active Catalysts for Alkyne Z‐Semihydrogenation
inferred← citeshttps://doi.org/10.1002/ejoc.202300435openalex-snapshot
Synthesis of C2‐Functionalized Pyrimidine Derivatives by Using Arynes and Dithiopyrimidines
inferred← citeshttps://doi.org/10.1002/ejoc.202400827openalex-snapshot
Magnetite: a Green, Sustainable and Recyclable Catalyst for Direct Synthesis of Thioesters by C−H Activation
inferred← citeshttps://doi.org/10.1002/jhet.4186openalex-snapshot
Design, synthesis, and evaluation of novel combretastatin A‐4 based chalcone derivatives as anticancer agents
inferred← citeshttps://doi.org/10.1002/med.21536openalex-snapshot
Polyphenolic natural products and natural product–inspired steroidal mimics as aromatase inhibitors
inferred← citeshttps://doi.org/10.1002/minf.202200016openalex-snapshot
Exploring the Gallic and Cinnamic Acids Chimeric Derivatives as Anticancer Agents over HeLa Cell Line: An in silico and in vitro Study
inferred← citeshttps://doi.org/10.1002/pauz.200700243openalex-snapshot
Angiogenese‐Inhibitoren der Zukunft. Getreu dem Motto: Von der Versorgung abschnüren!
inferred← citeshttps://doi.org/10.1002/slct.201904434openalex-snapshot
Solvent‐Free Synthesis and In Vitro Antitumor Activity of a New Class of ( Z )‐3‐Arylidene‐1 H ‐pyrano[3,4‐ b ]quinolin‐4(3 H )‐ones
inferred← citeshttps://doi.org/10.1002/slct.202003860openalex-snapshot
Design, Synthesis and Biological Evaluation of Stilbene Derivatives Containing a 1,3‐Benzodioxole Moiety
inferred← citeshttps://doi.org/10.1002/slct.202200238openalex-snapshot
Coumarin‐Chalcones Generated from 3‐Acetylcoumarin as a Promising Agent: Synthesis and Pharmacological Properties
inferred← citeshttps://doi.org/10.1002/slct.202200910openalex-snapshot
Visible‐Light‐Promoted Synthesis of Arylthiopyrimidines through Oxidative Coupling of Pyrimidine Disulfides with Arylhydrazines
inferred← citeshttps://doi.org/10.1002/slct.202405188openalex-snapshot
Design, Synthesis, and Molecular Docking Studies of 2‐Azetidinone‐Based Combretastatin A‐4 Analogues with Anticancer Activity
inferred← citeshttps://doi.org/10.1002/tcr.201700098openalex-snapshot
Transition Metal‐Catalyzed Dicarbofunctionalization of Unactivated Olefins
inferred← citeshttps://doi.org/10.1002/tcr.202100083openalex-snapshot
(Z)‐Selective Hydrosilylation and Hydroboration of Terminal Alkynes Enabled by Ruthenium Complexes with an N‐Heterocyclic Carbene Ligand
inferred← citeshttps://doi.org/10.1007/128_2008_20openalex-snapshot
Molecular Modeling Approaches to Study the Binding Mode on Tubulin of Microtubule Destabilizing and Stabilizing Agents
inferred← citeshttps://doi.org/10.1007/7081_2007_103openalex-snapshot
Tumor Specificity and the Type of Cell Death Induced by Heterocycles
inferred← citeshttps://doi.org/10.1007/978-3-7643-8117-2_1openalex-snapshot
Mother Nature’s gifts to diseases of man: the impact of natural products on anti-infective, anticholestemics and anticancer drug discovery
inferred← citeshttps://doi.org/10.1007/978-3-7643-8117-2_2openalex-snapshot
Drug discovery and development with plant-derived compounds
inferred← citeshttps://doi.org/10.1007/978-981-10-4284-3_8openalex-snapshot
Cancer Combating Biomolecules From Plants
inferred← citeshttps://doi.org/10.1007/s00044-011-9887-7openalex-snapshot
Synthesis of combretastatin analogs: evaluation of in vitro anticancer activity and molecular docking studies
inferred← citeshttps://doi.org/10.1007/s00044-013-0556-xopenalex-snapshot
Synthesis, biological evaluation, and molecular modeling studies of novel heterocyclic compounds as anti-proliferative agents
inferred← citeshttps://doi.org/10.1007/s00044-019-02352-2openalex-snapshot
An overview of tubulin modulators deposited in protein data bank
inferred← citeshttps://doi.org/10.1007/s00044-019-02406-5openalex-snapshot
New pyranoquinoline derivatives as vascular-disrupting anticancer agents
inferred← citeshttps://doi.org/10.1007/s00044-020-02632-2openalex-snapshot
Synthesis, biological evaluation and molecular docking studies of Combretastatin A-4 phosphoramidates as novel anticancer prodrugs
inferred← citeshttps://doi.org/10.1007/s00044-022-02969-wopenalex-snapshot
Synthesis,characterization and biological activities of nitrogen-containing Combretastatin A-4 derivatives
inferred← citeshttps://doi.org/10.1007/s00280-007-0549-xopenalex-snapshot
A novel class of tubulin inhibitors that exhibit potent antiproliferation and in vitro vessel-disrupting activity
inferred← citeshttps://doi.org/10.1007/s00706-014-1227-4openalex-snapshot
Oxydehydrogenative aromatization of fused 3-aminopyran-2-ones on carbon surfaces: a simple approach towards 3-amino-5-hydroxycoumarin derivatives
inferred← citeshttps://doi.org/10.1007/s00706-017-2001-1openalex-snapshot
Synthesis and cytotoxic evaluation of combretastatin A-4 analogues of benzo[b]furans
inferred← citeshttps://doi.org/10.1007/s10456-013-9343-zopenalex-snapshot
TR-644 a novel potent tubulin binding agent induces impairment of endothelial cells function and inhibits angiogenesis
inferred← citeshttps://doi.org/10.1007/s10616-018-0227-3openalex-snapshot
Cytotoxic, tubulin-interfering and proapoptotic activities of 4′-methylthio-trans-stilbene derivatives, analogues of trans-resveratrol
inferred← citeshttps://doi.org/10.1007/s10637-010-9547-7openalex-snapshot
Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents
inferred← citeshttps://doi.org/10.1007/s10637-015-0215-9openalex-snapshot
Combretastatin A-4 derived imidazoles show cytotoxic, antivascular, and antimetastatic effects based on cytoskeletal reorganisation
inferred← citeshttps://doi.org/10.1007/s10822-018-0109-yopenalex-snapshot
Insight into microtubule destabilization mechanism of 3,4,5-trimethoxyphenyl indanone derivatives using molecular dynamics simulation and conformational modes analysis
inferred← citeshttps://doi.org/10.1007/s10870-016-0633-3openalex-snapshot
Synthesis, Crystal Structure and Cytotoxic Properties of Nitrocombretastatins (E)- and (Z)-5-(4-Methoxy-3-nitrostyryl)-1,2,3-trimethoxybenzene
inferred← citeshttps://doi.org/10.1007/s11030-018-9886-4openalex-snapshot
5-Oxo-hexahydroquinoline: an attractive scaffold with diverse biological activities
inferred← citeshttps://doi.org/10.1007/s11030-020-10050-0openalex-snapshot
Molecular docking studies, biological evaluation and synthesis of novel 3-mercapto-1,2,4-triazole derivatives
inferred← citeshttps://doi.org/10.1007/s11094-018-1706-8openalex-snapshot
Synthesis and Antiproliferative Activity Evaluation of Aryl(Hetaryl)Cyclopentenone Analogs of Combretastatin A-4
inferred← citeshttps://doi.org/10.1007/s11094-023-02977-zopenalex-snapshot
Synthesis, Antiproliferative, and Molecular Docking Studies of 3-Mercapto-1,2,4-Triazole Derivatives as Combretastatin A-4 Analogs
inferred← citeshttps://doi.org/10.1007/s11095-012-0828-zopenalex-snapshot
An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site
inferred← citeshttps://doi.org/10.1007/s11172-007-0391-7openalex-snapshot
Polyalkoxybenzenes from plant sources 2. Synthesis of isoxazoline analogs of combretastatin from natural allyl(methylenedioxy)methoxybenzenes
inferred← citeshttps://doi.org/10.1007/s11172-010-0130-3openalex-snapshot
Synthesis of 4-(2-hydroxymethylaryl)coumarins
inferred← citeshttps://doi.org/10.1007/s11172-010-0387-6openalex-snapshot
Polyalkoxybenzenes from plant raw materials 4. Parsley and dill seed extracts in the synthesis of polyalkoxy-3,5-diaryl-1,2,4-oxadiazoles with antiproliferative activity
inferred← citeshttps://doi.org/10.1007/s11172-011-0030-1openalex-snapshot
New transformation of α-acetylenic ketones under the action of 1,2-diaminoethane
inferred← citeshttps://doi.org/10.1007/s11172-011-0304-7openalex-snapshot
Synthesis of hydrophilic and lipophilic 4-arylcoumarin phosphates
inferred← citeshttps://doi.org/10.1007/s11172-013-0149-3openalex-snapshot
Novel water-soluble anticancer agents derived from 4-arylcoumarins
inferred← citeshttps://doi.org/10.1007/s11172-015-0883-9openalex-snapshot
Synthesis and antimitotic activity of alkoxy-substituted 1-aryl-3-(arylamino)alkenones
inferred← citeshttps://doi.org/10.1007/s11172-018-2150-3openalex-snapshot
Synthesis of 3,4-diaryl- and 4-acyl-3-arylpyrroles and study of their antimitotic activity
inferred← citeshttps://doi.org/10.1007/s11696-025-03959-zopenalex-snapshot
Theoretical studies on the structures and properties of combretastatin A-4 and its five-membered heterocyclic structural analogs
inferred← citeshttps://doi.org/10.1007/s11696-026-05153-1openalex-snapshot
Classification and QSAR of the anticancer activity of (E)-stilbenes
inferred← citeshttps://doi.org/10.1007/s12039-018-1520-6openalex-snapshot
Design and synthesis of (Z/E)-2-phenyl/H-3-styryl-2H-chromene derivatives as antimicrotubule agents
inferred← citeshttps://doi.org/10.1007/s13402-015-0243-7openalex-snapshot
Role of JNK and NF-κB in mediating the effect of combretastatin A-4 and brimamin on endothelial and carcinoma cells
inferred← citeshttps://doi.org/10.1007/s43450-025-00672-6openalex-snapshot
Preclinical Exploration of Newer Curcumin Analog (NSC 793122) as Potential Antiproliferative Agent
inferred← citeshttps://doi.org/10.1016/b978-0-08-102237-5.00004-3openalex-snapshot
Synthesis and Biological Profiles of 4,5-, 1,5-, and 1,2-Diaryl-1 H -imidazoles
inferred← citeshttps://doi.org/10.1016/b978-0-12-385464-3.00001-7openalex-snapshot
The Literature of Heterocyclic Chemistry, Part X, 2005–2007
inferred← citeshttps://doi.org/10.1016/b978-0-323-96025-0.00162-9openalex-snapshot
Heterogeneous Hydrogenation of C=C and C≡C Bonds
inferred← citeshttps://doi.org/10.1016/b978-0-443-15635-9.00016-xopenalex-snapshot
Prodrugs for cancer therapy
inferred← citeshttps://doi.org/10.1016/b978-008045382-8.00033-2openalex-snapshot
Terrestrial Plants as a Source of Novel Pharmaceutical Agents
inferred← citeshttps://doi.org/10.1016/b978-008045382-8.00064-2openalex-snapshot
Natural Products Drug Discovery
inferred← citeshttps://doi.org/10.1016/j.apsb.2022.09.022openalex-snapshot
Harnessing the cyclization strategy for new drug discovery
inferred← citeshttps://doi.org/10.1016/j.bioorg.2016.02.007openalex-snapshot
Combretastatin linked 1,3,4-oxadiazole conjugates as a Potent Tubulin Polymerization inhibitors
inferred← citeshttps://doi.org/10.1016/j.bioorg.2017.04.007openalex-snapshot
Development of combretastatins as potent tubulin polymerization inhibitors
inferred← citeshttps://doi.org/10.1016/j.bioorg.2019.103300openalex-snapshot
Design, synthesis and biological evaluation of flexible and rigid analogs of 4H-1,2,4-triazoles bearing 3,4,5-trimethoxyphenyl moiety as new antiproliferative agents
inferred← citeshttps://doi.org/10.1016/j.bioorg.2019.103392openalex-snapshot
Synthesis and biological evaluation of 1-(benzofuran-3-yl)-4-(3,4,5-trimethoxyphenyl)-1H-1,2,3-triazole derivatives as tubulin polymerization inhibitors
inferred← citeshttps://doi.org/10.1016/j.bioorg.2020.103755openalex-snapshot
Potent colchicine-site ligands with improved intrinsic solubility by replacement of the 3,4,5-trimethoxyphenyl ring with a 2-methylsulfanyl-6-methoxypyridine ring
inferred← citeshttps://doi.org/10.1016/j.bioorg.2021.105239openalex-snapshot
Design, synthesis and antitumor evaluation of novel chiral diaryl substituted azetidin-2-one derivatives as tubulin polymerization inhibitors
inferred← citeshttps://doi.org/10.1016/j.bioorg.2022.105919openalex-snapshot
Efficient synthesis of artificial pharmaceutical solid-phase modules for constructing aptamer-drug conjugates
inferred← citeshttps://doi.org/10.1016/j.bioorg.2024.107299openalex-snapshot
Design, synthesis and biological evaluation of new 2,6-difluorinated phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new antimicrotubule agents
inferred← citeshttps://doi.org/10.1016/j.bioorg.2026.109943openalex-snapshot
Design, synthesis, and biological evaluation of Indazole-based CA-4 analogues as tubulin polymerization inhibitors
inferred← citeshttps://doi.org/10.1016/j.biopha.2019.109781openalex-snapshot
The stilbene and dibenzo[b,f]oxepine derivatives as anticancer compounds
inferred← citeshttps://doi.org/10.1016/j.biopha.2020.110973openalex-snapshot
Development of novel derivatives of stilbene and macrocyclic compounds as potent of anti-microtubule factors
inferred← citeshttps://doi.org/10.1016/j.bmc.2007.02.006openalex-snapshot
The concise synthesis of chalcone, indanone and indenone analogues of combretastatin A4
inferred← citeshttps://doi.org/10.1016/j.bmc.2007.05.030openalex-snapshot
Antimitotic activities of 2-phenylindole-3-carbaldehydes in human breast cancer cells
inferred← citeshttps://doi.org/10.1016/j.bmc.2007.07.006openalex-snapshot
Synthesis and bioactivities of 6,7,8-trimethoxy-N-aryl-4-aminoquinazoline derivatives
inferred← citeshttps://doi.org/10.1016/j.bmc.2007.10.078openalex-snapshot
N-Phenyl-N′-(2-chloroethyl)ureas (CEUs) as potential antineoplastic agents. Part 3: Role of carbonyl groups in the covalent binding to the colchicine-binding site
inferred← citeshttps://doi.org/10.1016/j.bmc.2007.11.048openalex-snapshot
Synthesis and biological evaluation of imidazol-2-one derivatives as potential antitumor agents
inferred← citeshttps://doi.org/10.1016/j.bmc.2008.03.049openalex-snapshot
1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin
inferred← citeshttps://doi.org/10.1016/j.bmc.2008.04.054openalex-snapshot
Diarylmethyloxime and hydrazone derivatives with 5-indolyl moieties as potent inhibitors of tubulin polymerization
inferred← citeshttps://doi.org/10.1016/j.bmc.2008.06.002openalex-snapshot
Synthesis and biological evaluation of new disubstituted analogues of 6-methoxy-3-(3′,4′,5′-trimethoxybenzoyl)-1H-indole (BPR0L075), as potential antivascular agents
inferred← citeshttps://doi.org/10.1016/j.bmc.2008.07.050openalex-snapshot
Design, synthesis and biological evaluation of dihydronaphthalene and benzosuberene analogs of the combretastatins as inhibitors of tubulin polymerization in cancer chemotherapy
inferred← citeshttps://doi.org/10.1016/j.bmc.2008.08.029openalex-snapshot
Synthesis and biological evaluation of 2-(3′,4′,5′-trimethoxybenzoyl)-3-N,N-dimethylamino benzo[b]furan derivatives as inhibitors of tubulin polymerization
inferred← citeshttps://doi.org/10.1016/j.bmc.2008.08.040openalex-snapshot
Naphthylphenstatins as tubulin ligands: Synthesis and biological evaluation
inferred← citeshttps://doi.org/10.1016/j.bmc.2008.09.003openalex-snapshot
Synthesis and biological evaluation of polymethoxylated 4-heteroarylcoumarins as tubulin assembly inhibitor
inferred← citeshttps://doi.org/10.1016/j.bmc.2009.03.037openalex-snapshot
Design, synthesis, and quantitative structure–activity relationship of cytotoxic γ-carboline derivatives
inferred← citeshttps://doi.org/10.1016/j.bmc.2009.07.012openalex-snapshot
Isocombretastatins A: 1,1-Diarylethenes as potent inhibitors of tubulin polymerization and cytotoxic compounds
inferred← citeshttps://doi.org/10.1016/j.bmc.2009.07.040openalex-snapshot
Synthesis and biological evaluation of 3,4-diaryl-5-aminoisoxazole derivatives
inferred← citeshttps://doi.org/10.1016/j.bmc.2009.07.076openalex-snapshot
E-Combretastatin and E-resveratrol structural modifications: Antimicrobial and cancer cell growth inhibitory β-E-nitrostyrenes
inferred← citeshttps://doi.org/10.1016/j.bmc.2009.08.027openalex-snapshot
Design, synthesis and structure–activity relationship of 2-(3′,4′,5′-trimethoxybenzoyl)-benzo[b]furan derivatives as a novel class of inhibitors of tubulin polymerization
inferred← citeshttps://doi.org/10.1016/j.bmc.2009.09.039openalex-snapshot
Combretastatin-like chalcones as inhibitors of microtubule polymerization. Part 1: Synthesis and biological evaluation of antivascular activity
inferred← citeshttps://doi.org/10.1016/j.bmc.2009.09.044openalex-snapshot
Combretastatin-like chalcones as inhibitors of microtubule polymerisation. Part 2: Structure-based discovery of alpha-aryl chalcones
inferred← citeshttps://doi.org/10.1016/j.bmc.2010.03.006openalex-snapshot
Pyrazolone-fused combretastatins and their precursors: synthesis, cytotoxicity, antitubulin activity and molecular modeling studies
inferred← citeshttps://doi.org/10.1016/j.bmc.2010.05.068openalex-snapshot
Substituted 2-(3′,4′,5′-trimethoxybenzoyl)-benzo[b]thiophene derivatives as potent tubulin polymerization inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmc.2010.07.032openalex-snapshot
1,2,3-Triazole analogs of combretastatin A-4 as potential microtubule-binding agents
inferred← citeshttps://doi.org/10.1016/j.bmc.2010.10.047openalex-snapshot
Design, synthesis, and biological evaluation of novel N-γ-carboline arylsulfonamides as anticancer agents
inferred← citeshttps://doi.org/10.1016/j.bmc.2010.11.035openalex-snapshot
Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk.
inferred← citeshttps://doi.org/10.1016/j.bmc.2011.02.022openalex-snapshot
Synthesis, evaluation and structural studies of antiproliferative tubulin-targeting azetidin-2-ones
inferred← citeshttps://doi.org/10.1016/j.bmc.2011.03.068openalex-snapshot
Imidazolone–amide bridges and their effects on tubulin polymerization in cis-locked vinylogous combretastatin-A4 analogues: Synthesis and biological evaluation
inferred← citeshttps://doi.org/10.1016/j.bmc.2011.08.068openalex-snapshot
1,1-Diarylalkenes as anticancer agents: Dual inhibitors of tubulin polymerization and phosphodiesterase 4
inferred← citeshttps://doi.org/10.1016/j.bmc.2011.11.010openalex-snapshot
Synthesis, biological evaluation and molecular modeling of 1,2,3-triazole analogs of combretastatin A-1
inferred← citeshttps://doi.org/10.1016/j.bmc.2011.11.057openalex-snapshot
Design, synthesis, biological evaluation and molecular modeling of 1,3,4-oxadiazoline analogs of combretastatin-A4 as novel antitubulin agents
inferred← citeshttps://doi.org/10.1016/j.bmc.2012.01.010openalex-snapshot
Increased endothelial cell selectivity of triazole-bridged dihalogenated A-ring analogues of combretastatin A–1
inferred← citeshttps://doi.org/10.1016/j.bmc.2012.02.057openalex-snapshot
Synthesis and anticancer activity of 2-benzylidene indanones through inhibiting tubulin polymerization
inferred← citeshttps://doi.org/10.1016/j.bmc.2012.03.057openalex-snapshot
Synthesis, biological evaluation, and molecular docking studies of 2,6-dinitro-4-(trifluoromethyl)phenoxysalicylaldoxime derivatives as novel antitubulin agents
inferred← citeshttps://doi.org/10.1016/j.bmc.2012.04.010openalex-snapshot
Synthesis of chalcone-amidobenzothiazole conjugates as antimitotic and apoptotic inducing agents
inferred← citeshttps://doi.org/10.1016/j.bmc.2012.10.001openalex-snapshot
Synthesis and biological evaluation of 2-substituted-4-(3′,4′,5′-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents
inferred← citeshttps://doi.org/10.1016/j.bmc.2012.11.056openalex-snapshot
Synthesis and biological evaluation of enantiomerically pure cyclopropyl analogues of combretastatin A4
inferred← citeshttps://doi.org/10.1016/j.bmc.2012.12.046openalex-snapshot
Synthesis and mechanistic studies of novel spin-labeled combretastatin derivatives as potential antineoplastic agents
inferred← citeshttps://doi.org/10.1016/j.bmc.2013.03.064openalex-snapshot
Synthesis and biological evaluation of fluoro analogues of antimitotic phenstatin
inferred← citeshttps://doi.org/10.1016/j.bmc.2013.06.046openalex-snapshot
Design and synthesis of 6,7-methylenedioxy-4-substituted phenylquinolin-2(1H)-one derivatives as novel anticancer agents that induce apoptosis with cell cycle arrest at G2/M phase
inferred← citeshttps://doi.org/10.1016/j.bmc.2013.09.046openalex-snapshot
Design and synthesis of silicon-containing tubulin polymerization inhibitors: Replacement of the ethylene moiety of combretastatin A-4 with a silicon linker
inferred← citeshttps://doi.org/10.1016/j.bmc.2013.09.064openalex-snapshot
Synthesis of combretastatin A-4 O-alkyl derivatives and evaluation of their cytotoxic, antiangiogenic and antitelomerase activity
inferred← citeshttps://doi.org/10.1016/j.bmc.2013.12.015openalex-snapshot
Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lines
inferred← citeshttps://doi.org/10.1016/j.bmc.2014.04.027openalex-snapshot
Synthesis, biological evaluation and molecular docking studies of trans-indole-3-acrylamide derivatives, a new class of tubulin polymerization inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmc.2014.06.042openalex-snapshot
Concise syntheses of 7-anilino-indoline-N-benzenesulfonamides as antimitotic and vascular disrupting agents
inferred← citeshttps://doi.org/10.1016/j.bmc.2014.08.008openalex-snapshot
Synthesis and biological evaluation of 1,2,3-triazole linked aminocombretastatin conjugates as mitochondrial mediated apoptosis inducers
inferred← citeshttps://doi.org/10.1016/j.bmc.2014.12.027openalex-snapshot
Natural antitubulin agents: Importance of 3,4,5-trimethoxyphenyl fragment
inferred← citeshttps://doi.org/10.1016/j.bmc.2015.04.055openalex-snapshot
Synthesis and biological evaluation of diarylthiazole derivatives as antimitotic and antivascular agents with potent antitumor activity
inferred← citeshttps://doi.org/10.1016/j.bmc.2015.11.007openalex-snapshot
Synthesis and bio-evaluation of novel quinolino-stilbene derivatives as potential anticancer agents
inferred← citeshttps://doi.org/10.1016/j.bmc.2016.01.007openalex-snapshot
Design, synthesis, and biological evaluation of water-soluble amino acid prodrug conjugates derived from combretastatin, dihydronaphthalene, and benzosuberene-based parent vascular disrupting agents
inferred← citeshttps://doi.org/10.1016/j.bmc.2016.12.010openalex-snapshot
Synthesis and biological evaluation of cis-restricted triazole/tetrazole mimics of combretastatin-benzothiazole hybrids as tubulin polymerization inhibitors and apoptosis inducers
inferred← citeshttps://doi.org/10.1016/j.bmc.2017.01.035openalex-snapshot
Synthesis and biological evaluation of 4 arylcoumarin analogues as tubulin-targeting antitumor agents
inferred← citeshttps://doi.org/10.1016/j.bmc.2017.02.046openalex-snapshot
Development of a novel near-infrared fluorescent theranostic combretastain A-4 analogue, YK-5-252, to target triple negative breast cancer
inferred← citeshttps://doi.org/10.1016/j.bmc.2017.07.048openalex-snapshot
Constructing novel dihydrofuran and dihydroisoxazole analogues of isocombretastatin-4 as tubulin polymerization inhibitors through [3+2] reactions
inferred← citeshttps://doi.org/10.1016/j.bmc.2017.10.045openalex-snapshot
Design, synthesis, and biological evaluation of hydantoin bridged analogues of combretastatin A-4 as potential anticancer agents
inferred← citeshttps://doi.org/10.1016/j.bmc.2018.09.025openalex-snapshot
Sterically induced conformational restriction: Discovery and preclinical evaluation of novel pyrrolo[3,2-d]pyrimidines as microtubule targeting agents
inferred← citeshttps://doi.org/10.1016/j.bmc.2020.115985openalex-snapshot
Synthesis and bioevaluation of N-(3,4,5-trimethoxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3-amines as tubulin polymerization inhibitors with anti-angiogenic effects
inferred← citeshttps://doi.org/10.1016/j.bmc.2023.117489openalex-snapshot
Development of QTMP: A promising anticancer agent through NP-Privileged Motif-Driven structural modulation
inferred← citeshttps://doi.org/10.1016/j.bmcl.2006.08.087openalex-snapshot
Novel imidazole-based combretastatin A-4 analogues: Evaluation of their in vitro antitumor activity and molecular modeling study of their binding to the colchicine site of tubulin
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