On the public citation graph

Identification of RO4597014, a Glucokinase Activator Studied in the Clinic for the Treatment of Type 2 Diabetes

https://doi.org/10.1021/ml400027y
0 signed · 34 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.
Claim with ORCID
Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.
See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/j.bmc.2009.05.037openalex-snapshot
The design and optimization of a series of 2-(pyridin-2-yl)-1H-benzimidazole compounds as allosteric glucokinase activators
inferredcites →https://doi.org/10.1016/j.bmc.2012.03.008openalex-snapshot
Design, synthesis, and pharmacological evaluation of benzamide derivatives as glucokinase activators
inferredcites →https://doi.org/10.1016/j.bmcl.2006.02.022openalex-snapshot
Design of a potent, soluble glucokinase activator with excellent in vivo efficacy
inferredcites →https://doi.org/10.1016/j.bmcl.2009.01.053openalex-snapshot
Identification of novel and potent 2-amino benzamide derivatives as allosteric glucokinase activators
inferredcites →https://doi.org/10.1021/cr00032a009openalex-snapshot
Catalytic Asymmetric Dihydroxylation
inferredcites →https://doi.org/10.1021/jm100039aopenalex-snapshot
Discovery, Structure−Activity Relationships, Pharmacokinetics, and Efficacy of Glucokinase Activator (2R)-3-Cyclopentyl-2-(4-methanesulfonylphenyl)-N-thiazol-2-yl-propionamide (RO0281675)
inferredcites →https://doi.org/10.1021/jm2014887openalex-snapshot
Discovery of (S)-6-(3-Cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic Acid as a Hepatoselective Glucokinase Activator Clinical Candidate for Treating Type 2 Diabetes Mellitus
inferredcites →https://doi.org/10.1021/jm3008689openalex-snapshot
Discovery of Piragliatin—First Glucokinase Activator Studied in Type 2 Diabetic Patients
inferredcites →https://doi.org/10.1021/jm8003202openalex-snapshot
SAR, Pharmacokinetics, Safety, and Efficacy of Glucokinase Activating 2-(4-Sulfonylphenyl)-N-thiazol-2-ylacetamides: Discovery of PSN-GK1
inferredcites →https://doi.org/10.1021/jm900839kopenalex-snapshot
Investigation of Functionally Liver Selective Glucokinase Activators for the Treatment of Type 2 Diabetes
inferredcites →https://doi.org/10.1021/tx200211vopenalex-snapshot
Improving Drug Candidates by Design: A Focus on Physicochemical Properties As a Means of Improving Compound Disposition and Safety
inferredcites →https://doi.org/10.1038/nrd2850openalex-snapshot
Assessing the potential of glucokinase activators in diabetes therapy
inferredcites →https://doi.org/10.1039/c1md00092fopenalex-snapshot
Matrix-based multiparameter optimisation of glucokinase activators: the discovery of AZD1092
inferredcites →https://doi.org/10.1039/c2md20077eopenalex-snapshot
Property based optimisation of glucokinase activators – discovery of the phase IIb clinical candidate AZD1656
inferredcites →https://doi.org/10.1126/science.1084073openalex-snapshot
Allosteric Activators of Glucokinase: Potential Role in Diabetes Therapy
inferredcites →https://doi.org/10.2337/dc11-1200openalex-snapshot
Effects of MK-0941, a Novel Glucokinase Activator, on Glycemic Control in Insulin-Treated Patients With Type 2 Diabetes

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4087303openalex-extracted
Small Molecules as Modulators of Active Forms of MMPs
inferred← citeshttps://doi.org/10.1002/0471264229.os098.04openalex-snapshot
Palladium‐Catalyzed Acetylation of Arylbromides
inferred← citeshttps://doi.org/10.1002/ejoc.201900503openalex-snapshot
BF 3 ·SMe 2 for Thiomethylation, Nitro Reduction and Tandem Reduction/SMe Insertion of Nitrogen Heterocycles
inferred← citeshttps://doi.org/10.1016/b978-0-32-390644-9.00032-9openalex-snapshot
Industrial Applications of Asymmetric Oxidations
inferred← citeshttps://doi.org/10.1016/j.biochi.2023.10.021openalex-snapshot
Small molecular exogenous modulators of active forms of MMPs
inferred← citeshttps://doi.org/10.1021/acs.chemrestox.2c00036openalex-snapshot
Use of Solvent Mapping for Characterizing the Binding Site and for Predicting the Inhibition of the Human Ether-á-Go-Go-Related K+ Channel
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.1c02110openalex-snapshot
Discovery of a Partial Glucokinase Activator Clinical Candidate: Diethyl ((3-(3-((5-(Azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-isopropoxybenzamido)-1H-pyrazol-1-yl)methyl)phosphonate (BMS-820132)
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5b01594openalex-snapshot
Structure–Activity Relationship of Azaindole-Based Glucokinase Activators
inferred← citeshttps://doi.org/10.1021/acs.joc.6b00116openalex-snapshot
Conversion of 3,3,3-Trisubstituted Prop-1-ynes with tert-Butylhydrazine into 3,3,3-Trisubstituted Propionitriles Catalyzed by TpRh(C2H4)2/P(2-furyl)3
inferred← citeshttps://doi.org/10.1021/ml5004712openalex-snapshot
Design and Synthesis of Acetylenyl Benzamide Derivatives as Novel Glucokinase Activators for the Treatment of T2DM
inferred← citeshttps://doi.org/10.1021/ol403570zopenalex-snapshot
Palladium-Catalyzed Acetylation of Arenes
inferred← citeshttps://doi.org/10.1039/9781788016414-00403openalex-snapshot
Cardiac Ion Channel Inhibition
inferred← citeshttps://doi.org/10.1039/c3md00053bopenalex-snapshot
N -substituted sultam carboxylic acids as novel glycogen synthase activators
inferred← citeshttps://doi.org/10.1111/cbdd.13979openalex-snapshot
A comprehensive review on glucokinase activators: Promising agents for the treatment of Type 2 diabetes
inferred← citeshttps://doi.org/10.1134/s1990750825600219openalex-snapshot
Activating Effect of Avarol and Damiron A from Sea Sponges on α-N-Acetylgalactosaminidase from Human Colorectal Cancer Cell Cultures
inferred← citeshttps://doi.org/10.1517/13543776.2014.918957openalex-snapshot
A patent review of glucokinase activators and disruptors of the glucokinase – glucokinase regulatory protein interaction: 2011 – 2014
inferred← citeshttps://doi.org/10.2174/1381612826666200414163148openalex-snapshot
Recent Developments in Medicinal Chemistry of Allosteric Activators of Human Glucokinase for Type 2 Diabetes Mellitus Therapeutics
inferred← citeshttps://doi.org/10.70675/95d49fabz6ca4z4b31z8099zc3c87d8000b4openalex-snapshot
Modulateurs synthétiques de la kallikréine 6, protéase à sérine impliquée dans les maladies neurodégénératives : identification, mécanisme d’action et validation de concept
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.