On the public citation graph
A high-throughput drug screen for Entamoeba histolytica identifies a new lead and target
0 signed · 343 inferred · view as graph
Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.
Is this your work? Sign in with ORCID and put your name on the
claims that are yours.
Reference health. See whether every reference in this work resolves to a
known work and none has been retracted — and get a dated CiteStamped
badge you can embed.
What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1006/prep.1996.0698openalex-snapshot
Application of a Single-Plasmid Vector for Mutagenesis and High-Level Expression of Thioredoxin Reductase and Its Use to Examine Flavin Cofactor Incorporation
inferredcites →https://doi.org/10.1007/s004360000339openalex-snapshot
Inhibition of encystation of Entamoeba invadens by wortmannin
inferredcites →https://doi.org/10.1007/s004360100453openalex-snapshot
Effect of calcium antagonists, calcium channel blockers and calmodulin inhibitors on the growth and encystation of Entamoeba histolytica and E. invadens
inferredcites →https://doi.org/10.1007/s00726-011-0997-9openalex-snapshot
A gold-containing drug against parasitic polyamine metabolism: the X-ray structure of trypanothione reductase from Leishmania infantum in complex with auranofin reveals a dual mechanism of enzyme inhibition
inferredcites →https://doi.org/10.1016/0035-9203(78)90144-xopenalex-snapshot
A new medium for the axenic cultivation of Entamoeba histolytica and other Entamoeba
inferredcites →https://doi.org/10.1016/0272-0590(88)90152-2openalex-snapshot
Carcinogenicity study of auranofin, an orally administered gold compound, in mice
inferredcites →https://doi.org/10.1016/0305-0491(73)90070-9openalex-snapshot
Purine metabolism in primitive erythrocytes
inferredcites →https://doi.org/10.1016/j.bmcl.2005.08.103openalex-snapshot
Synthesis, spectral studies and in vitro assessment for antiamoebic activity of new cyclooctadiene ruthenium(II) complexes with 5-nitrothiophene-2-carboxaldehyde thiosemicarbazones
inferredcites →https://doi.org/10.1016/j.cell.2005.02.016openalex-snapshot
A Rae1-Containing Ribonucleoprotein Complex Is Required for Mitotic Spindle Assembly
inferredcites →https://doi.org/10.1016/j.febslet.2008.02.028openalex-snapshot
New uses for old drugs. Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro : Mechanistic and pharmacological implications
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2007.02.012openalex-snapshot
Thioredoxin-linked metabolism in Entamoeba histolytica
inferredcites →https://doi.org/10.1016/j.molbiopara.2006.10.014openalex-snapshot
Transcriptomic comparison of two Entamoeba histolytica strains with defined virulence phenotypes identifies new virulence factor candidates and key differences in the expression patterns of cysteine proteases, lectin light chains, and calmodulin
inferredcites →https://doi.org/10.1016/j.yexcr.2004.07.026openalex-snapshot
Nm23-M2/NDP kinase B induces endogenous c-myc and nm23-M1/NDP kinase A overexpression in BAF3 cells. Both NDP kinases protect the cells from oxidative stress-induced death
inferredcites →https://doi.org/10.1016/s0076-6879(02)47031-0openalex-snapshot
Protein Electrophoretic Mobility Shift Assay to Monitor Redox State of Thioredoxin in Cells
inferredcites →https://doi.org/10.1016/s0753-3322(03)00043-xopenalex-snapshot
The importance of glutathione in human disease
inferredcites →https://doi.org/10.1016/s1471-4922(02)02293-6openalex-snapshot
The diversity and evolution of thioredoxin reductase: new perspectives
inferredcites →https://doi.org/10.1021/bi0349928openalex-snapshot
Characterization of Saccharomyces cerevisiae Ras1p and Chimaeric Constructs of Ras Proteins Reveals the Hypervariable Region and Farnesylation as Critical Elements in the Adenylyl Cyclase Signaling Pathway
inferredcites →https://doi.org/10.1021/jm030084xopenalex-snapshot
Effects of Bisphosphonates on the Growth ofEntamoeba histolyticaandPlasmodiumSpecies in Vitro and in Vivo
inferredcites →https://doi.org/10.1038/bjp.2008.161openalex-snapshot
Arsenic trioxide and auranofin inhibit selenoprotein synthesis: implications for chemotherapy for acute promyelocytic leukaemia
inferredcites →https://doi.org/10.1038/nm1737openalex-snapshot
Identification of oxadiazoles as new drug leads for the control of schistosomiasis
inferredcites →https://doi.org/10.1038/nrd1468openalex-snapshot
Drug repositioning: identifying and developing new uses for existing drugs
inferredcites →https://doi.org/10.1046/j.1432-1327.2000.01702.xopenalex-snapshot
Thioredoxin reductase
inferredcites →https://doi.org/10.1073/pnas.0701549104openalex-snapshot
Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide
inferredcites →https://doi.org/10.1074/jbc.274.37.26051openalex-snapshot
Metronidazole Resistance in the Protozoan Parasite Entamoeba histolytica Is Associated with Increased Expression of Iron-containing Superoxide Dismutase and Peroxiredoxin and Decreased Expression of Ferredoxin 1 and Flavin Reductase
inferredcites →https://doi.org/10.1074/jbc.m109.020701openalex-snapshot
Inhibition of Schistosoma mansoni Thioredoxin-glutathione Reductase by Auranofin
inferredcites →https://doi.org/10.1074/jbc.m109.086181openalex-snapshot
A Novel Entamoeba histolytica Cysteine Proteinase, EhCP4, Is Key for Invasive Amebiasis and a Therapeutic Target
inferredcites →https://doi.org/10.1074/jbc.m110.106310openalex-snapshot
Two Atypical l-Cysteine-regulated NADPH-dependent Oxidoreductases Involved in Redox Maintenance, l-Cystine and Iron Reduction, and Metronidazole Activation in the Enteric Protozoan Entamoeba histolytica
inferredcites →https://doi.org/10.1074/jbc.m710609200openalex-snapshot
Platyhelminth Mitochondrial and Cytosolic Redox Homeostasis Is Controlled by a Single Thioredoxin Glutathione Reductase and Dependent on Selenium and Glutathione
inferredcites →https://doi.org/10.1080/15027732.1986.12461436openalex-snapshot
Pharmacology of Auranofin: Overview and Update
inferredcites →https://doi.org/10.1089/ars.2007.9.25openalex-snapshot
Thioredoxin and Related Molecules–From Biology to Health and Disease
inferredcites →https://doi.org/10.1093/jac/40.6.833openalex-snapshot
Involvement of superoxide dismutase and pyruvate:ferredoxin oxidoreductase in mechanisms of metronidazole resistance in Entamoeba histolytica
inferredcites →https://doi.org/10.1093/nar/gkl541openalex-snapshot
Selenium metabolism in Trypanosoma: characterization of selenoproteomes and identification of a Kinetoplastida-specific selenoprotein
inferredcites →https://doi.org/10.1126/science.6322306openalex-snapshot
Entamoeba histolytica : a Eukaryote Without Glutathione Metabolism
inferredcites →https://doi.org/10.1128/aac.45.5.1505-1510.2001openalex-snapshot
Effects of Miltefosine and Other Alkylphosphocholines on Human Intestinal Parasite Entamoeba histolytica
inferredcites →https://doi.org/10.1128/ec.00094-07openalex-snapshot
Use of RecombinantEntamoeba histolyticaCysteine Proteinase 1 To Identify a Potent Inhibitor of Amebic Invasion in a Human Colonic Model
inferredcites →https://doi.org/10.1128/ec.00308-06openalex-snapshot
The 29-Kilodalton Thiol-Dependent Peroxidase of Entamoeba histolytica Is a Factor Involved in Pathogenesis and Survival of the Parasite during Oxidative Stress
inferredcites →https://doi.org/10.1371/journal.pmed.0040206openalex-snapshot
Thioredoxin Glutathione Reductase from Schistosoma mansoni: An Essential Parasite Enzyme and a Key Drug Target
inferredcites →https://doi.org/10.1379/1466-1268(2001)006<0006:airapa>2.0.co;2openalex-snapshot
Arsenite-inducible RNA-associated protein (AIRAP) protects cells from arsenite toxicity
inferredcites →https://doi.org/10.4049/jimmunol.169.8.4496openalex-snapshot
The Mouse Model of Amebic Colitis Reveals Mouse Strain Susceptibility to Infection and Exacerbation of Disease by CD4+ T Cells
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4821603openalex-extracted
The Inhibition Mechanism of Auranofin on Thioredoxin Reductase 1 at the Molecular Level: A New Use of the Old Drug
inferred← citeshttps://doi.org/10.1002/0471266949.bmc288openalex-snapshot
Anti‐Infective Case Histories
inferred← citeshttps://doi.org/10.1002/9783527682386.ch8openalex-snapshot
Identification of Anti‐infective Compounds Using Amoebae
inferred← citeshttps://doi.org/10.1002/advs.202105442openalex-snapshot
Microglia Regulate Blood–Brain Barrier Integrity via MiR‐126a‐5p/MMP9 Axis during Inflammatory Demyelination
inferred← citeshttps://doi.org/10.1002/ardp.202000168openalex-snapshot
Reprogramming of antibiotics to combat antimicrobial resistance
inferred← citeshttps://doi.org/10.1002/ardp.202000263openalex-snapshot
Amoebicidal effect of 5,5′‐[(4‐nitrophenyl)methylene]bis‐6‐hydroxy‐2‐mercapto‐3‐methyl‐4(3H)‐pyrimidinone), a new drug against Entamoeba histolytica
inferred← citeshttps://doi.org/10.1002/cbic.201300273openalex-snapshot
Substrate Selection Influences Molecular Recognition in a Screen for Lymphoid Tyrosine Phosphatase Inhibitors
inferred← citeshttps://doi.org/10.1002/chem.201604512openalex-snapshot
Gold(I) NHC Complexes: Antiproliferative Activity, Cellular Uptake, Inhibition of Mammalian and Bacterial Thioredoxin Reductases, and Gram‐Positive Directed Antibacterial Effects
inferred← citeshttps://doi.org/10.1002/cmdc.201402240openalex-snapshot
In Vitro Antiamoebic Activity Evaluation and Docking Studies of Metronidazole–Triazole Hybrids
inferred← citeshttps://doi.org/10.1002/cmdc.202100381openalex-snapshot
Gold(I) and Gold(III) N‐Heterocyclic Carbene Complexes as Antibacterial Agents and Inhibitors of Bacterial Thioredoxin Reductase
inferred← citeshttps://doi.org/10.1002/elan.202100378openalex-snapshot
Electrochemical Characterization of the Repurposed Antimicrobial Compound Auranofin in Aqueous Solutions
inferred← citeshttps://doi.org/10.1002/iub.1867openalex-snapshot
Redox‐guided small molecule antimycobacterials
inferred← citeshttps://doi.org/10.1007/7355_2021_127openalex-snapshot
Management of Entamoeba histolytica Infection: Treatment Strategies and Possible New Drug Targets
inferred← citeshttps://doi.org/10.1007/978-1-4939-9080-1_5openalex-snapshot
One-Step Generation of Seamless Luciferase Gene Knockin Using CRISPR/Cas9 Genome Editing in Human Pluripotent Stem Cells
inferred← citeshttps://doi.org/10.1007/978-1-4939-9080-1_7openalex-snapshot
Using Human Neural Progenitor Cell Models to Conduct Large-Scale Drug Screens for Neurological and Psychiatric Diseases
inferred← citeshttps://doi.org/10.1007/978-3-030-32036-2_10openalex-snapshot
Polymer-Functionalized NIR-Emitting Nanoparticles: Applications in Cancer Theranostics and Treatment of Bacterial Infections
inferred← citeshttps://doi.org/10.1007/978-3-030-44826-4_12openalex-snapshot
Oxidative Stress and Heat Stress in Experimental Amoebic Liver Abscess
inferred← citeshttps://doi.org/10.1007/978-3-319-30705-3_30openalex-snapshot
Redox-Active Metal Complexes in Trypanosomatids
inferred← citeshttps://doi.org/10.1007/978-3-319-46718-4_40openalex-snapshot
Drug Resistance Mechanisms in Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis, and Opportunistic Anaerobic Protozoa
inferred← citeshttps://doi.org/10.1007/978-4-431-55200-0_30openalex-snapshot
Metronidazole and the Redox Biochemistry of Entamoeba histolytica
inferred← citeshttps://doi.org/10.1007/978-4-431-55200-0_31openalex-snapshot
Thioredoxin Reductase and Its Role as a New Drug Target
inferred← citeshttps://doi.org/10.1007/978-4-431-55200-0_32openalex-snapshot
Drug Development: Old Drugs and New Lead
inferred← citeshttps://doi.org/10.1007/978-981-13-8763-0_11openalex-snapshot
Oxidative Stress and Antioxidant Defense Mechanism in the Human Enteric Protozoan Parasite Entamoeba histolytica
inferred← citeshttps://doi.org/10.1007/s00018-021-03786-xopenalex-snapshot
An unusual thioredoxin system in the facultative parasite Acanthamoeba castellanii
inferred← citeshttps://doi.org/10.1007/s00203-019-01764-3openalex-snapshot
Antibiofilm and antibacterial activities of repurposing auranofin against Bacteroides fragilis
inferred← citeshttps://doi.org/10.1007/s00436-019-06580-8openalex-snapshot
Biological activity of esters of quinoxaline-7-carboxylate 1,4-di-N-oxide against E. histolytica and their analysis as potential thioredoxin reductase inhibitors
inferred← citeshttps://doi.org/10.1007/s00436-020-06868-0openalex-snapshot
Rabeprazole inhibits several functions of Entamoeba histolytica related with its virulence
inferred← citeshttps://doi.org/10.1007/s00436-021-07354-xopenalex-snapshot
Drug repositioning: antiprotozoal activity of terfenadine against Entamoeba histolytica trophozoites
inferred← citeshttps://doi.org/10.1007/s10534-015-9870-8openalex-snapshot
Synthesis, characterization, cytotoxic and antitubercular activities of new gold(I) and gold(III) complexes containing ligands derived from carbohydrates
inferred← citeshttps://doi.org/10.1007/s10637-019-00750-2openalex-snapshot
A high-throughput drug screen identifies auranofin as a potential sensitizer of cisplatin in small cell lung cancer
inferred← citeshttps://doi.org/10.1007/s10787-012-0149-1openalex-snapshot
The biological activity of auranofin: implications for novel treatment of diseases
inferred← citeshttps://doi.org/10.1007/s12011-017-1149-1openalex-snapshot
A Spectroscopic Study of Interaction of Auricyanide with n-Acetylcysteine
inferred← citeshttps://doi.org/10.1007/s12247-026-10401-8openalex-snapshot
Computational Investigation of FDA-Approved Compounds for Thiol Reductase Inhibition To Overcome Amebiasis Using Docking and SMD-based Simulation Analysis
inferred← citeshttps://doi.org/10.1007/s13361-019-02319-yopenalex-snapshot
Ligand Exchange/Scrambling Study of Gold(I)-Phosphine Complexes in the Solid Phase by DESI-MS Analysis
inferred← citeshttps://doi.org/10.1007/s40588-015-0023-1openalex-snapshot
Molecular Basis of Pathogenesis in Amoebiasis
inferred← citeshttps://doi.org/10.1007/s40588-019-0113-6openalex-snapshot
Tissue Destruction Caused by Entamoeba histolytica Parasite: Cell Death, Inflammation, Invasion, and the Gut Microbiome
inferred← citeshttps://doi.org/10.1016/b978-0-08-102688-5.00018-0openalex-snapshot
Metal Complexes as Drugs and Therapeutic Agents
inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.12411-4openalex-snapshot
Antiparasitic Agents
inferred← citeshttps://doi.org/10.1016/b978-0-12-816476-1.00020-4openalex-snapshot
Carbonic anhydrases from pathogens
inferred← citeshttps://doi.org/10.1016/b978-0-12-818480-6.00005-9openalex-snapshot
Repurposing nonantibiotic drugs as antibacterials
inferred← citeshttps://doi.org/10.1016/b978-0-12-822521-9.00236-7openalex-snapshot
Entamoeba histolytica
inferred← citeshttps://doi.org/10.1016/b978-0-323-75608-2.00263-9openalex-snapshot
Entamoeba histolytica (Amebiasis)
inferred← citeshttps://doi.org/10.1016/bs.adioch.2019.11.001openalex-snapshot
150 years of the periodic table: New medicines and diagnostic agents
inferred← citeshttps://doi.org/10.1016/bs.apar.2019.11.003openalex-snapshot
Drug resistance in Giardia: Mechanisms and alternative treatments for Giardiasis
inferred← citeshttps://doi.org/10.1016/bs.enz.2025.07.006openalex-snapshot
Entamoeba histolytica carbonic anhydrase
inferred← citeshttps://doi.org/10.1016/j.abb.2026.110841openalex-snapshot
Characterization of a novel non-canonical thioredoxin from Entamoeba histolytica specific to cystine reduction
inferred← citeshttps://doi.org/10.1016/j.actatropica.2026.108131openalex-snapshot
Evaluation of the effect of auranofin alone and in combination with nitazoxanide on Cryptosporidium parvum in immunosuppressed mice
inferred← citeshttps://doi.org/10.1016/j.apsb.2025.12.014openalex-snapshot
Intratumoral immune-microbial crosstalk shaped by tumor cell-derived extracellular vesicles encapsulating berberine boosts lung cancer immunotherapy
inferred← citeshttps://doi.org/10.1016/j.bbagen.2012.08.020openalex-snapshot
Entamoeba histolytica thioredoxin reductase: Molecular and functional characterization of its atypical properties
inferred← citeshttps://doi.org/10.1016/j.bbagen.2016.09.029openalex-snapshot
Ebselen exerts antifungal activity by regulating glutathione (GSH) and reactive oxygen species (ROS) production in fungal cells
inferred← citeshttps://doi.org/10.1016/j.bbapap.2014.01.006openalex-snapshot
Antiglioma activity of GoPI-sugar, a novel gold(I)–phosphole inhibitor: Chemical synthesis, mechanistic studies, and effectiveness in vivo
inferred← citeshttps://doi.org/10.1016/j.bbi.2023.03.008openalex-snapshot
GPR55 contributes to neutrophil recruitment and mechanical pain induction after spinal cord compression in mice
inferred← citeshttps://doi.org/10.1016/j.biocel.2015.05.016openalex-snapshot
Evidence that the antiproliferative effects of auranofin in Saccharomyces cerevisiae arise from inhibition of mitochondrial respiration
inferred← citeshttps://doi.org/10.1016/j.biopha.2017.07.022openalex-snapshot
Combatting Bacterial Persister cell infections by auranofin?
inferred← citeshttps://doi.org/10.1016/j.bmc.2023.117167openalex-snapshot
Auranofin inhibits virulence pathways in Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.1016/j.ccr.2023.215323openalex-snapshot
Molecular mechanisms and clinical implications of the gold drug auranofin
inferred← citeshttps://doi.org/10.1016/j.ccr.2024.216208openalex-snapshot
Functional utility of gold complexes with phosphorus donor ligands in biological systems
inferred← citeshttps://doi.org/10.1016/j.ccr.2025.217354openalex-snapshot
Golden keys to inflammation: decoding the anti-inflammatory mechanisms of gold(I) and gold(III) complexes (2010–present)
inferred← citeshttps://doi.org/10.1016/j.diagmicrobio.2024.116413openalex-snapshot
Auranofin enhances the antibacterial effects of ertapenem against carbapenem-resistant Escherichia coli
inferred← citeshttps://doi.org/10.1016/j.drup.2019.04.003openalex-snapshot
Target identification and intervention strategies against amebiasis
inferred← citeshttps://doi.org/10.1016/j.ebiom.2017.09.034openalex-snapshot
Chloroquine, a FDA-approved Drug, Prevents Zika Virus Infection and its Associated Congenital Microcephaly in Mice
inferred← citeshttps://doi.org/10.1016/j.ebiom.2019.04.029openalex-snapshot
Phenotypic screening of nonsteroidal anti-inflammatory drugs identified mefenamic acid as a drug for the treatment of schistosomiasis
inferred← citeshttps://doi.org/10.1016/j.ejmech.2015.06.019openalex-snapshot
Metronidazole-triazole conjugates: Activity against Clostridium difficile and parasites
inferred← citeshttps://doi.org/10.1016/j.ejmech.2016.04.064openalex-snapshot
Nitroimidazole carboxamides as antiparasitic agents targeting Giardia lamblia, Entamoeba histolytica and Trichomonas vaginalis
inferred← citeshttps://doi.org/10.1016/j.ejmech.2016.08.053openalex-snapshot
Synthesis, antiamoebic and molecular docking studies of furan-thiazolidinone hybrids
inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.04.057openalex-snapshot
Structural characterization of Giardia duodenalis thioredoxin reductase ( g TrxR) and computational analysis of its interaction with NBDHEX
inferred← citeshttps://doi.org/10.1016/j.ejmech.2018.03.033openalex-snapshot
Synthesis, antiamoebic activity and docking studies of metronidazole-triazole-styryl hybrids
inferred← citeshttps://doi.org/10.1016/j.ejmech.2019.111711openalex-snapshot
Recent progress on anti-Toxoplasma drugs discovery: Design, synthesis and screening
inferred← citeshttps://doi.org/10.1016/j.etap.2021.103805openalex-snapshot
Effects of short-term selenium exposure on respiratory activity and proximate body composition of early-life stages of Catla catla, Labeo rohita and Cirrhinus mrigala
inferred← citeshttps://doi.org/10.1016/j.ijantimicag.2015.12.016openalex-snapshot
Repurposing auranofin for the treatment of cutaneous staphylococcal infections
inferred← citeshttps://doi.org/10.1016/j.ijantimicag.2016.09.020openalex-snapshot
Auranofin inactivates Trichomonas vaginalis thioredoxin reductase and is effective against trichomonads in vitro and in vivo
inferred← citeshttps://doi.org/10.1016/j.ijantimicag.2021.106425openalex-snapshot
Antimicrobial effect of auranofin against Acanthamoeba spp.
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2020.09.096openalex-snapshot
Thiol antioxidant thioredoxin reductase: A prospective biochemical crossroads between anticancer and antiparasitic treatments of the modern era
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2026.150992openalex-snapshot
Unveiling the mechanistic link between peroxiredoxin inhibition and ferroptosis-like cell death induced by Dinaciclib in Entamoeba histolytica
inferred← citeshttps://doi.org/10.1016/j.ijmm.2019.151358openalex-snapshot
Intestinal amoebiasis: 160 years of its first detection and still remains as a health problem in developing countries
inferred← citeshttps://doi.org/10.1016/j.ijpddr.2014.02.002openalex-snapshot
Drug repurposing and human parasitic protozoan diseases
inferred← citeshttps://doi.org/10.1016/j.ijpddr.2016.07.003openalex-snapshot
Evaluation of Giardia lamblia thioredoxin reductase as drug activating enzyme and as drug target
inferred← citeshttps://doi.org/10.1016/j.ijpddr.2017.09.001openalex-snapshot
Drug susceptibility testing in microaerophilic parasites: Cysteine strongly affects the effectivities of metronidazole and auranofin, a novel and promising antimicrobial
inferred← citeshttps://doi.org/10.1016/j.ijpddr.2017.11.004openalex-snapshot
An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes
inferred← citeshttps://doi.org/10.1016/j.ijpddr.2019.10.003openalex-snapshot
Identification of plicamycin, TG02, panobinostat, lestaurtinib, and GDC-0084 as promising compounds for the treatment of central nervous system infections caused by the free-living amebae Naegleria, Acanthamoeba and Balamuthia
inferred← citeshttps://doi.org/10.1016/j.jbiosc.2013.09.017openalex-snapshot
Characterization of antibacterial activity of bikaverin from Fusarium sp. HKF15
inferred← citeshttps://doi.org/10.1016/j.jinorgbio.2014.05.008openalex-snapshot
Auranofin and related heterometallic gold(I)–thiolates as potent inhibitors of methicillin-resistant Staphylococcus aureus bacterial strains
inferred← citeshttps://doi.org/10.1016/j.jinorgbio.2015.12.020openalex-snapshot
Alkynyl gold(I) phosphane complexes: Evaluation of structure–activity-relationships for the phosphane ligands, effects on key signaling proteins and preliminary in-vivo studies with a nanoformulated complex
inferred← citeshttps://doi.org/10.1016/j.jinorgbio.2020.111023openalex-snapshot
Anti-fibrotic activity of gold and platinum complexes – Au(I) compounds as a new class of anti-fibrotic agents
inferred← citeshttps://doi.org/10.1016/j.jinorgbio.2025.113133openalex-snapshot
Investigations of gold(I) complexes as inhibitors of caspase-1
inferred← citeshttps://doi.org/10.1016/j.jinorgbio.2026.113315openalex-snapshot
Anticancer gold complexes: Controlled activation, precision targeting and beyond
inferred← citeshttps://doi.org/10.1016/j.jsb.2016.02.015openalex-snapshot
X-ray structures of thioredoxin and thioredoxin reductase from Entamoeba histolytica and prevailing hypothesis of the mechanism of Auranofin action
inferred← citeshttps://doi.org/10.1016/j.micpath.2025.107867openalex-snapshot
Parasitic protozoa: Biosystematics, identification, pathogenicity, causes and remedial measures
inferred← citeshttps://doi.org/10.1016/j.mjafi.2012.10.005openalex-snapshot
The symposium on hepatic abscess: Controversy, analysis and addendum
inferred← citeshttps://doi.org/10.1016/j.molbiopara.2016.01.004openalex-snapshot
Entamoeba thiol-based redox metabolism: A potential target for drug development
inferred← citeshttps://doi.org/10.1016/j.molbiopara.2020.111301openalex-snapshot
Direct and high-throughput assays for human cell killing through trogocytosis by Entamoeba histolytica
inferred← citeshttps://doi.org/10.1016/j.molbiopara.2021.111363openalex-snapshot
Ultra-structural analysis and morphological changes during the differentiation of trophozoite to cyst in Entamoeba invadens
inferred← citeshttps://doi.org/10.1016/j.molstruc.2022.134325openalex-snapshot
Vanillin allied 1,2,3- triazole as a selective sensor for detection of Al3+ ions: A potent inhibitor against Entamoeba histolytica
inferred← citeshttps://doi.org/10.1016/j.nxbio.2025.100004openalex-snapshot
Gold nanoparticles derived from Selaginella bryopteris extract provide neuroprotection and ameliorate oxidative stress induced neurodegeneration in human neuronal cells (SH-SY5Y) model
inferred← citeshttps://doi.org/10.1016/j.pan.2021.04.002openalex-snapshot
New high-throughput screening detects compounds that suppress pancreatic stellate cell activation and attenuate pancreatic cancer growth
inferred← citeshttps://doi.org/10.1016/j.parint.2015.10.006openalex-snapshot
Activity, stability and folding analysis of the chitinase from Entamoeba histolytica
inferred← citeshttps://doi.org/10.1016/j.pt.2015.05.003openalex-snapshot
Chew on this: amoebic trogocytosis and host cell killing by Entamoeba histolytica
inferred← citeshttps://doi.org/10.1016/j.pt.2018.04.007openalex-snapshot
Redox Pathways as Drug Targets in Microaerophilic Parasites
inferred← citeshttps://doi.org/10.1016/j.rvsc.2021.02.021openalex-snapshot
Review of zoonotic amebiasis: Epidemiology, clinical signs, diagnosis, treatment, prevention and control
inferred← citeshttps://doi.org/10.1016/j.vetpar.2024.110295openalex-snapshot
Auranofin is lethal against feline Tritrichomonas foetus in vitro but ineffective in cats with naturally occurring infection
inferred← citeshttps://doi.org/10.1016/j.virusres.2018.11.013openalex-snapshot
RETRACTED: Evaluation of imidazole and its derivative against Newcastle disease virus infection in chicken: A drug repurposing approach
inferred← citeshttps://doi.org/10.1017/s0031182018000252openalex-snapshot
Nuclear transport inEntamoeba histolytica: knowledge gap and therapeutic potential
inferred← citeshttps://doi.org/10.1021/acs.analchem.5b04077openalex-snapshot
Microfluidic Sample Preparation for Single Cell Analysis
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.0c01926openalex-snapshot
Gold(I) Phosphine Derivatives with Improved Selectivity as Topically Active Drug Leads to Overcome 5-Nitroheterocyclic Drug Resistance in Trichomonas vaginalis
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.3c01898openalex-snapshot
Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri-Specific CYP51 Inhibitors
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.4c00669openalex-snapshot
The “Doorstop Pocket” In Thioredoxin Reductases─An Unexpected Druggable Regulator of the Catalytic Machinery
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.6b00795openalex-snapshot
Water-Soluble Ruthenium (II) Chiral Heteroleptic Complexes with Amoebicidal in Vitro and in Vivo Activity
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.8b01578openalex-snapshot
Design, Synthesis, and Biological Evaluation of 2-Nitroimidazopyrazin-one/-es with Antitubercular and Antiparasitic Activity
inferred← citeshttps://doi.org/10.1021/acsami.7b10116openalex-snapshot
Real-Time Continuous Identification of Greenhouse Plant Pathogens Based on Recyclable Microfluidic Bioassay System
inferred← citeshttps://doi.org/10.1021/acschemneuro.0c00165openalex-snapshot
Activity of Auranofin against Multiple Genotypes of Naegleria fowleri and Its Synergistic Effect with Amphotericin B In Vitro
inferred← citeshttps://doi.org/10.1021/acsinfecdis.1c00418openalex-snapshot
In Vitro and In Vivo Antiamebic Activity of Iron-Targeting Polypyridine Compounds against Enteric Protozoan Parasite Entamoeba histolytica
inferred← citeshttps://doi.org/10.1021/acsinfecdis.9b00315openalex-snapshot
Innovations in Addressing Pediatric Diarrhea in Low Resource Settings
inferred← citeshttps://doi.org/10.1021/acsomega.5c03735openalex-snapshot
Eleutherine plicata Herb. and Its Promising Constituents Amoebicides
inferred← citeshttps://doi.org/10.1021/acsomega.9b00529openalex-snapshot
Dynamic Basis for Auranofin Drug Recognition by Thiol-Reductases of Human Pathogens and Intermediate Coordinated Adduct Formation with Catalytic Cysteine Residues
inferred← citeshttps://doi.org/10.1021/acssensors.6c02096openalex-snapshot
Real-Time Nanoscale Multiparametric Biophysical Phenotyping of Single Cells by Surface Plasmon Resonance Microscopy
inferred← citeshttps://doi.org/10.1021/cb400800qopenalex-snapshot
Auranofin Is an Apoptosis-Simulating Agent within Vitroandin VivoAnti-leishmanial Activity
inferred← citeshttps://doi.org/10.1021/jacs.5c18554openalex-snapshot
Chem–Bio Hybrid Synthesis Enables Reengineering of Natural Product-Based Methionine Aminopeptidase 2 Inhibitors for Treating Amebiasis
inferred← citeshttps://doi.org/10.1021/jacs.7b01084openalex-snapshot
Metal Ions Effectively Ablate the Action of Botulinum Neurotoxin A
inferred← citeshttps://doi.org/10.1021/ma502263xopenalex-snapshot
Glycopolymer Self-Assemblies with Gold(I) Complexed to the Core as a Delivery System for Auranofin
inferred← citeshttps://doi.org/10.1038/cddis.2017.100openalex-snapshot
Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer
inferred← citeshttps://doi.org/10.1038/emm.2013.30openalex-snapshot
G protein signaling in the parasite Entamoeba histolytica
inferred← citeshttps://doi.org/10.1038/nm.4184openalex-snapshot
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
inferred← citeshttps://doi.org/10.1038/nrgastro.2012.112openalex-snapshot
High-throughput drug screen strikes gold in the search for a new amoebiasis treatment
inferred← citeshttps://doi.org/10.1038/s41419-020-02890-3openalex-snapshot
Computational repositioning of dimethyl fumarate for treating alcoholic liver disease
inferred← citeshttps://doi.org/10.1038/s41467-025-62634-9openalex-snapshot
Ligand supplementation restores the cancer therapy efficacy of the antirheumatic drug auranofin from serum inactivation
inferred← citeshttps://doi.org/10.1038/s41564-019-0357-1openalex-snapshot
Drug repurposing for antimicrobial discovery
inferred← citeshttps://doi.org/10.1038/s41598-017-15969-3openalex-snapshot
The Immunomodulatory Drug Glatiramer Acetate is Also an Effective Antimicrobial Agent that Kills Gram-negative Bacteria
inferred← citeshttps://doi.org/10.1038/s41598-018-28625-1openalex-snapshot
Interaction between parasite-encoded JAB1/CSN5 and macrophage migration inhibitory factor proteins attenuates its proinflammatory function
inferred← citeshttps://doi.org/10.1038/s41598-021-90360-xopenalex-snapshot
Investigating auranofin for the treatment of infected diabetic pressure ulcers in mice and dermal toxicity in pigs
inferred← citeshttps://doi.org/10.1038/srep04668openalex-snapshot
Designing of promiscuous inhibitors against pancreatic cancer cell lines
inferred← citeshttps://doi.org/10.1038/srep22571openalex-snapshot
Antibacterial activity and mechanism of action of auranofin against multi-drug resistant bacterial pathogens
inferred← citeshttps://doi.org/10.1038/srep35852openalex-snapshot
Extensive transcriptome analysis correlates the plasticity of Entamoeba histolytica pathogenesis to rapid phenotype changes depending on the environment
inferred← citeshttps://doi.org/10.1039/c3cc41143eopenalex-snapshot
Exploration of the medical periodic table: towards new targets
inferred← citeshttps://doi.org/10.1039/c5gc00084jopenalex-snapshot
Selective S-deacetylation inspired by native chemical ligation: practical syntheses of glycosyl thiols and drug mercapto-analogues
inferred← citeshttps://doi.org/10.1039/c6gc02908fopenalex-snapshot
An efficient approach to chloro(organophosphine) gold( i ) complexes for the synthesis of auranofin
inferred← citeshttps://doi.org/10.1039/c6md00013dopenalex-snapshot
New transition metal complexes containing imidazole rings endowed with potential antiamoebic activity
inferred← citeshttps://doi.org/10.1039/c7md00269fopenalex-snapshot
Biscarbene gold( i ) complexes: structure–activity-relationships regarding antibacterial effects, cytotoxicity, TrxR inhibition and cellular bioavailability
inferred← citeshttps://doi.org/10.1039/c7md00434fopenalex-snapshot
Design, synthesis and preliminary antimicrobial evaluation of N-alkyl chain-tethered C-5 functionalized bis-isatins
inferred← citeshttps://doi.org/10.1039/c8an01079jopenalex-snapshot
Single-cell assay on microfluidic devices
inferred← citeshttps://doi.org/10.1039/c9an01902bopenalex-snapshot
A hairpin DNA-fueled nanoflare for simultaneous illumination of two microRNAs in drug-induced nephrotoxic cells with target catalytic recycling amplification
inferred← citeshttps://doi.org/10.1039/d0sc04082gopenalex-snapshot
Metallodrugs are unique: opportunities and challenges of discovery and development
inferred← citeshttps://doi.org/10.1039/d3dt03581fopenalex-snapshot
Folate-assisted targeted photocytotoxicity of red-light-activable iron( iii ) complex co-functionalized gold nanoconjugates (Fe@FA-AuNPs) against HeLa and triple-negative MDA-MB-231 cancer cells
inferred← citeshttps://doi.org/10.1039/d4md00358fopenalex-snapshot
Gold( i ) and gold( iii ) carbene complexes from the marine betaine norzooanemonin: inhibition of thioredoxin reductase, antiproliferative and antimicrobial activity
inferred← citeshttps://doi.org/10.1042/bj20121798openalex-snapshot
Entamoeba histolytica: identification of thioredoxin-targeted proteins and analysis of serine acetyltransferase-1 as a prototype example
inferred← citeshttps://doi.org/10.1051/parasite/2022025openalex-snapshot
Transcriptional changes of proteins of the thioredoxin and glutathione systems in Acanthamoeba spp. under oxidative stress – an RNA approach
inferred← citeshttps://doi.org/10.1055/a-1111-9566openalex-snapshot
Anti-amoebic Activity of Leaf Extracts and Aporphine Alkaloids Obtained from Annona purpurea
inferred← citeshttps://doi.org/10.1055/a-1809-1157openalex-snapshot
Potent Anti-amoebic Effects of Ibogaine, Voacangine and the Root Bark Alkaloid Fraction of Tabernaemontana arborea
inferred← citeshttps://doi.org/10.1056/nejmra1207777openalex-snapshot
Enteropathogens and Chronic Illness in Returning Travelers
inferred← citeshttps://doi.org/10.1073/pnas.2615451123openalex-snapshot
Cascading damage to Candida albicans cells through thioredoxin reductase loss
inferred← citeshttps://doi.org/10.1074/jbc.m115.695007openalex-snapshot
Leishmania donovani Encodes a Functional Selenocysteinyl-tRNA Synthase
inferred← citeshttps://doi.org/10.1080/21505594.2016.1196301openalex-snapshot
Repurposing auranofin as an antifungal: In vitro activity against a variety of medically important fungi
inferred← citeshttps://doi.org/10.1080/21505594.2021.1909266openalex-snapshot
Repurposing of auranofin and honokiol as antifungals against Scedosporium species and the related fungus Lomentospora prolificans
inferred← citeshttps://doi.org/10.1089/adt.2015.29011.tiodrrropenalex-snapshot
Computational and Practical Aspects of Drug Repositioning
inferred← citeshttps://doi.org/10.1089/drrr.2014.0009openalex-snapshot
Computational and Practical Aspects of Drug Repositioning
inferred← citeshttps://doi.org/10.1093/cid/ciy349openalex-snapshot
Why Funding for Neglected Tropical Diseases Should Be a Global Priority
inferred← citeshttps://doi.org/10.1093/femsle/fnw148openalex-snapshot
Auranofin andN-heterocyclic carbene gold-analogs are potent inhibitors of the bacteriaHelicobacter pylori
inferred← citeshttps://doi.org/10.1093/infdis/jix076openalex-snapshot
Entamoeba histolytica–Encoded Homolog of Macrophage Migration Inhibitory Factor Contributes to Mucosal Inflammation during Amebic Colitis
inferred← citeshttps://doi.org/10.1093/infdis/jix689openalex-snapshot
The Existing Drug Vorinostat as a New Lead Against Cryptosporidiosis by Targeting the Parasite Histone Deacetylases
inferred← citeshttps://doi.org/10.1093/infdis/jiz579openalex-snapshot
Targeting Parasite-Produced Macrophage Migration Inhibitory Factor as an Antivirulence Strategy With Antibiotic–Antibody Combination to Reduce Tissue Damage
inferred← citeshttps://doi.org/10.1093/jac/dkv163openalex-snapshot
Auranofin efficacy against MDRStreptococcus pneumoniaeandStaphylococcus aureusinfections
inferred← citeshttps://doi.org/10.1093/jac/dkz430openalex-snapshot
Repurposing auranofin as a Clostridioides difficile therapeutic
inferred← citeshttps://doi.org/10.1093/mmy/myz126openalex-snapshot
Encephalitozoon intestinalis: A new target for auranofin in a mice model
inferred← citeshttps://doi.org/10.1097/qco.0000000000000095openalex-snapshot
Noninvasive intestinal amebiasis
inferred← citeshttps://doi.org/10.1098/rsta.2014.0182openalex-snapshot
The elements of life and medicines
inferred← citeshttps://doi.org/10.1101/198820openalex-snapshot
Auranofin inhibits virulence in Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.1101/2020.05.28.120923openalex-snapshot
Antineoplastic kinase inhibitors: a new class of potent anti-amoebic compounds Antineoplastic kinase inhibitors against Entamoeba histolytica
inferred← citeshttps://doi.org/10.1101/723361openalex-snapshot
Screening the MMV Open Access Pathogen box unveils novel and potent inhibitors of Amoebiasis agent: Entamoeba histolytica
inferred← citeshttps://doi.org/10.1111/bph.13895openalex-snapshot
Drug repurposing screens and synergistic drug‐combinations for infectious diseases
inferred← citeshttps://doi.org/10.1111/cmi.13174openalex-snapshot
Formation of oxidised (OX) proteins in Entamoeba histolytica exposed to auranofin and consequences on the parasite virulence
inferred← citeshttps://doi.org/10.1111/jeu.12706openalex-snapshot
Antiparasitic Activity of Auranofin against Pathogenic Naegleria fowleri
inferred← citeshttps://doi.org/10.1124/pr.117.013755openalex-snapshot
Small-Molecule Screens: A Gateway to Cancer Therapeutic Agents with Case Studies of Food and Drug Administration–Approved Drugs
inferred← citeshttps://doi.org/10.1128/aac.00208-18openalex-snapshot
Viability Screen of LOPAC 1280 Reveals Phosphorylation Inhibitor Auranofin as a Potent Inhibitor of Blastocystis Subtype 1, 4, and 7 Isolates
inferred← citeshttps://doi.org/10.1128/aac.00560-23openalex-snapshot
Fumagillin inhibits growth of the enteric protozoan parasite Entamoeba histolytica by covalently binding to and selectively inhibiting methionine aminopeptidase 2
inferred← citeshttps://doi.org/10.1128/aac.00582-20openalex-snapshot
Discovery and Preclinical Development of Antigiardiasis Fumagillol Derivatives
inferred← citeshttps://doi.org/10.1128/aac.00643-12openalex-snapshot
Corifungin, a New Drug Lead against Naegleria, Identified from a High-Throughput Screen
inferred← citeshttps://doi.org/10.1128/aac.00680-13openalex-snapshot
High-Throughput Screening of a Collection of Known Pharmacologically Active Small Compounds for Identification of Candida albicans Biofilm Inhibitors
inferred← citeshttps://doi.org/10.1128/aac.00731-23openalex-snapshot
Antigiardial and antiamebic activities of fexinidazole and its metabolites: new drug leads for giardiasis and amebiasis
inferred← citeshttps://doi.org/10.1128/aac.00832-22openalex-snapshot
Alcohol Abuse Drug Disulfiram Is Effective against Cyst Stages of Entamoeba histolytica Parasite
inferred← citeshttps://doi.org/10.1128/aac.01207-21openalex-snapshot
Ponatinib, Lestaurtinib, and mTOR/PI3K Inhibitors Are Promising Repurposing Candidates against Entamoeba histolytica
inferred← citeshttps://doi.org/10.1128/aac.01675-12openalex-snapshot
A Reprofiled Drug, Auranofin, Is Effective against Metronidazole-Resistant Giardia lamblia
inferred← citeshttps://doi.org/10.1128/aac.01947-16openalex-snapshot
Phase I Clinical Trial Results of Auranofin, a Novel Antiparasitic Agent
inferred← citeshttps://doi.org/10.1128/aac.02223-19openalex-snapshot
The Antifungal Drug Isavuconazole Is both Amebicidal and Cysticidal against Acanthamoeba castellanii
inferred← citeshttps://doi.org/10.1128/aac.02541-14openalex-snapshot
Repurposing the Open Access Malaria Box To Discover Potent Inhibitors of Toxoplasma gondii and Entamoeba histolytica
inferred← citeshttps://doi.org/10.1128/aac.02576-14openalex-snapshot
Hsp90 Inhibitors as New Leads To Target Parasitic Diarrheal Diseases
inferred← citeshttps://doi.org/10.1128/cmr.00111-16openalex-snapshot
Susceptibility Testing of Medically Important Parasites
inferred← citeshttps://doi.org/10.1128/msphere.00347-24openalex-snapshot
Identification and characterization of archaeal-type FAD synthase as a novel tractable drug target from the parasitic protozoa Entamoeba histolytica
inferred← citeshttps://doi.org/10.1128/spectrum.00506-25openalex-snapshot
Exploring virulence and stress response in Entamoeba histolytica : insights from clinical strains
inferred← citeshttps://doi.org/10.1128/spectrum.01210-25openalex-snapshot
Entamoeba histolytica “mutator” strain with a high rate of genetic mutations assists the elucidation of drug resistance mechanisms
inferred← citeshttps://doi.org/10.1128/spectrum.02968-23openalex-snapshot
Gold(I) ion and the phosphine ligand are necessary for the anti- Toxoplasma gondii activity of auranofin
inferred← citeshttps://doi.org/10.1136/postgradmedj-2014-132597openalex-snapshot
Fulminant amoebic colitis: a clinicopathological study of 30 cases
inferred← citeshttps://doi.org/10.1146/annurev-micro-091313-103550openalex-snapshot
Regulation of Virulence ofEntamoeba histolytica
inferred← citeshttps://doi.org/10.1155/2014/324230openalex-snapshot
Peroxynitrite and Peroxiredoxin in the Pathogenesis of Experimental Amebic Liver Abscess
inferred← citeshttps://doi.org/10.1158/0008-5472.can-13-0712openalex-snapshot
KEAP1-Dependent Synthetic Lethality Induced by AKT and TXNRD1 Inhibitors in Lung Cancer
showing the first 200 of 302 · page through all 302
Editorial review for independent work. ICSAC — the Institute for Complexity
Science and Advanced Computing — runs a structured editorial panel for researchers
publishing outside journals, and publishes on CiteStamp rails. Submission is free
and goes through ORCID: icsacinstitute.org/submit.