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DNA damage stress response in germ cells: role of c-Abl and clinical implications

https://doi.org/10.1038/onc.2010.410
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Fertility preservation after chemotherapy for Hodgkin lymphoma
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Molecular characterization of the testis specific c‐abl mRNA in mouse.
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The cytostatic function of c‐Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene products.
inferredcites →https://doi.org/10.1002/pbc.21999openalex-snapshot
Preserving female fertility following cancer treatment: Current options and future possibilities
inferredcites →https://doi.org/10.1002/pbc.22012openalex-snapshot
Normal ovarian function and assessment of ovarian reserve in the survivor of childhood cancer
inferredcites →https://doi.org/10.1006/cimm.1996.0220openalex-snapshot
Abnormal Peripheral Lymphocyte Function in c-ablMutant Mice
inferredcites →https://doi.org/10.1006/excr.1993.1140openalex-snapshot
Differential Expression of the Proto-oncogenes c-abl and c-mos in Developing Mouse Germ Cells
inferredcites →https://doi.org/10.1006/geno.1998.5374openalex-snapshot
Cloning, Structural Characterization, and Chromosomal Localization of the Human Orthologue ofSaccharomyces cerevisiaeMSH5 Gene
inferredcites →https://doi.org/10.1006/jmbi.1997.1426openalex-snapshot
The 2.35 å crystal structure of the inactivated form of chicken src: a dynamic molecule with multiple regulatory interactions
inferredcites →https://doi.org/10.1007/978-0-387-72293-1_1openalex-snapshot
The Emergence of a New Interdiscipline: Oncofertility
inferredcites →https://doi.org/10.1007/978-0-387-72293-1_17openalex-snapshot
Oncofertility Consortium Consensus Statement: Guidelines for Ovarian Tissue Cryopreservation
inferredcites →https://doi.org/10.1007/s10549-009-0401-6openalex-snapshot
The fertility-related concerns, needs and preferences of younger women with breast cancer: a systematic review
inferredcites →https://doi.org/10.1007/s10815-010-9413-8openalex-snapshot
Using decision trees to enhance interdisciplinary team work: the case of oncofertility
inferredcites →https://doi.org/10.1007/s11864-010-0116-2openalex-snapshot
Maintaining Fertility in Young Women with Breast Cancer
inferredcites →https://doi.org/10.1016/0092-8674(80)90554-1openalex-snapshot
Structure of the Abelson murine leukemia virus genome and the homologous cellular gene: Studies with cloned viral DNA
inferredcites →https://doi.org/10.1016/0092-8674(91)90011-mopenalex-snapshot
Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene
inferredcites →https://doi.org/10.1016/0092-8674(91)90012-nopenalex-snapshot
Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations
inferredcites →https://doi.org/10.1016/0092-8674(93)90404-eopenalex-snapshot
SH2 domains recognize specific phosphopeptide sequences
inferredcites →https://doi.org/10.1016/0092-8674(94)90240-2openalex-snapshot
The nuclear tyrosine kinase c-abl negatively regulates cell growth
inferredcites →https://doi.org/10.1016/j.bbrc.2005.04.154openalex-snapshot
Two variants of MutS homolog hMSH5: Prevalence in humans and effects on protein interaction
inferredcites →https://doi.org/10.1016/j.bbrc.2009.03.020openalex-snapshot
c-ABL tyrosine kinase stabilizes RAD51 chromatin association
inferredcites →https://doi.org/10.1016/j.ceb.2007.02.009openalex-snapshot
DNA damage checkpoints: from initiation to recovery or adaptation
inferredcites →https://doi.org/10.1016/j.dnarep.2004.03.015openalex-snapshot
The mechanism of vertebrate nonhomologous DNA end joining and its role in V(D)J recombination
inferredcites →https://doi.org/10.1016/j.dnarep.2004.03.021openalex-snapshot
Role of DNA–PK in the cellular response to DNA double-strand breaks
inferredcites →https://doi.org/10.1016/j.dnarep.2004.03.026openalex-snapshot
The DNA double-strand break response pathway: becoming more BRCAish than ever
inferredcites →https://doi.org/10.1016/j.dnarep.2004.05.007openalex-snapshot
The role of the DNA double-strand break response network in meiosis
inferredcites →https://doi.org/10.1016/j.dnarep.2004.06.006openalex-snapshot
Mismatch repair and DNA damage signalling
inferredcites →https://doi.org/10.1016/j.dnarep.2006.12.009openalex-snapshot
Twists and turns in the function of DNA damage signaling and repair proteins by post-translational modifications
inferredcites →https://doi.org/10.1016/j.dnarep.2009.01.013openalex-snapshot
Regulatory ubiquitylation in response to DNA double-strand breaks
inferredcites →https://doi.org/10.1016/j.mod.2005.04.008openalex-snapshot
Differential expression of p63 isoforms in female reproductive organs
inferredcites →https://doi.org/10.1016/j.molcel.2006.04.021openalex-snapshot
A Kinase-Independent Function of c-Abl in Promoting Proteolytic Destruction of Damaged DNA Binding Proteins
inferredcites →https://doi.org/10.1016/j.molmed.2008.05.003openalex-snapshot
Nuclear trafficking of pro-apoptotic kinases in response to DNA damage
inferredcites →https://doi.org/10.1016/j.yexcr.2009.05.004openalex-snapshot
Evidence for a direct involvement of hMSH5 in promoting ionizing radiation induced apoptosis
inferredcites →https://doi.org/10.1016/s0027-5107(03)00009-5openalex-snapshot
Ionizing radiation-induced Rad51 nuclear focus formation is cell cycle-regulated and defective in both ATM−/− and c-Abl−/− cells
inferredcites →https://doi.org/10.1016/s0065-230x(02)85003-5openalex-snapshot
The Abl family kinases: Mechanisms of regulation and signaling
inferredcites →https://doi.org/10.1016/s0070-2153(04)59007-5openalex-snapshot
Death by Abl: A Matter of Location
inferredcites →https://doi.org/10.1016/s0079-6603(08)60611-xopenalex-snapshot
DNA Damage Produced by Ionizing Radiation in Mammalian Cells: Identities, Mechanisms of Formation, and Reparability
inferredcites →https://doi.org/10.1016/s0092-8674(00)80626-1openalex-snapshot
Drosophila p53 Is a Structural and Functional Homolog of the Tumor Suppressor p53
inferredcites →https://doi.org/10.1016/s0092-8674(00)80627-3openalex-snapshot
Drosophila p53 Binds a Damage Response Element at the reaper Locus
inferredcites →https://doi.org/10.1016/s0092-8674(03)00191-0openalex-snapshot
A Myristoyl/Phosphotyrosine Switch Regulates c-Abl
inferredcites →https://doi.org/10.1016/s0092-8674(03)00194-6openalex-snapshot
Structural Basis for the Autoinhibition of c-Abl Tyrosine Kinase
inferredcites →https://doi.org/10.1016/s0304-419x(97)00020-6openalex-snapshot
Functional role for the c-Abl protein tyrosine kinase in the cellular response to genotoxic stress
inferredcites →https://doi.org/10.1016/s0955-0674(00)00201-5openalex-snapshot
DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?
inferredcites →https://doi.org/10.1016/s0960-9822(01)00534-6openalex-snapshot
The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis
inferredcites →https://doi.org/10.1016/s0962-8924(03)00170-3openalex-snapshot
The cellular response to DNA double-strand breaks: defining the sensors and mediators
inferredcites →https://doi.org/10.1017/s1462399403006318openalex-snapshot
A multifaceted role for ATM in genome maintenance
inferredcites →https://doi.org/10.1021/bi00009a027openalex-snapshot
A Single HMG Domain in High-Mobility Group 1 Protein Binds to DNAs as Small as 20 Base Pairs Containing the Major Cisplatin Adduct
inferredcites →https://doi.org/10.1021/bi973030wopenalex-snapshot
The DNA Binding Domain of the Human c-Abl Tyrosine Kinase Preferentially Binds to DNA Sequences Containing an AAC Motif and to Distorted DNA Structures
inferredcites →https://doi.org/10.1038/21460openalex-snapshot
Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins
inferredcites →https://doi.org/10.1038/21690openalex-snapshot
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
inferredcites →https://doi.org/10.1038/21697openalex-snapshot
Interaction of c-Abl and p73α and their collaboration to induce apoptosis
inferredcites →https://doi.org/10.1038/299640a0openalex-snapshot
Differential expression of cellular oncogenes during pre- and postnatal development of the mouse
inferredcites →https://doi.org/10.1038/338087a0openalex-snapshot
Double-strand breaks at an initiation site for meiotic gene conversion
inferredcites →https://doi.org/10.1038/385595a0openalex-snapshot
Three-dimensional structure of the tyrosine kinase c-Src
inferredcites →https://doi.org/10.1038/386732a0openalex-snapshot
Functional interaction between DNA-PK and c-Abl in response to DNA damage
inferredcites →https://doi.org/10.1038/387516a0openalex-snapshot
Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation
inferredcites →https://doi.org/10.1038/387520a0openalex-snapshot
Interaction between ATM protein and c-Abl in response to DNA damage
inferredcites →https://doi.org/10.1038/5075openalex-snapshot
Mammalian MutS homologue 5 is required for chromosome pairing in meiosis
inferredcites →https://doi.org/10.1038/73542openalex-snapshot
Mice deficient in Abl are osteoporotic and have defects in osteoblast maturation
inferredcites →https://doi.org/10.1038/80442openalex-snapshot
Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine -1-phosphate therapy
inferredcites →https://doi.org/10.1038/84683openalex-snapshot
Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR–ABL tyrosine kinase
inferredcites →https://doi.org/10.1038/85798openalex-snapshot
DNA double-strand breaks: signaling, repair and the cancer connection
inferredcites →https://doi.org/10.1038/nature03097openalex-snapshot
Cell-cycle checkpoints and cancer
inferredcites →https://doi.org/10.1038/nature03442openalex-snapshot
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
inferredcites →https://doi.org/10.1038/nature03482openalex-snapshot
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
inferredcites →https://doi.org/10.1038/nature03485openalex-snapshot
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
inferredcites →https://doi.org/10.1038/nature05337openalex-snapshot
p63 protects the female germ line during meiotic arrest
inferredcites →https://doi.org/10.1038/nature06524openalex-snapshot
The origin of protein interactions and allostery in colocalization
inferredcites →https://doi.org/10.1038/nature08467openalex-snapshot
The DNA-damage response in human biology and disease
inferredcites →https://doi.org/10.1038/nature08675openalex-snapshot
Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors
inferredcites →https://doi.org/10.1038/ncb0104-3openalex-snapshot
Controlling Abl: auto-inhibition and co-inhibition?
inferredcites →https://doi.org/10.1038/ncb1004openalex-snapshot
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
inferredcites →https://doi.org/10.1038/ncb1228openalex-snapshot
JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage
inferredcites →https://doi.org/10.1038/ncb945openalex-snapshot
Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage
inferredcites →https://doi.org/10.1038/nchembio0206-63openalex-snapshot
Inhibitors of Bcr-abl... breaking new ground again
inferredcites →https://doi.org/10.1038/nchembio760openalex-snapshot
Allosteric inhibitors of Bcr-abl–dependent cell proliferation
inferredcites →https://doi.org/10.1038/ng1396openalex-snapshot
Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation
inferredcites →https://doi.org/10.1038/nm.2033openalex-snapshot
Inhibition of the c-Abl–TAp63 pathway protects mouse oocytes from chemotherapy-induced death
inferredcites →https://doi.org/10.1038/nm1009-1124openalex-snapshot
Preserving fertility during cancer treatment
inferredcites →https://doi.org/10.1038/nm1108-1190openalex-snapshot
Making eggs: is it now or later?
inferredcites →https://doi.org/10.1038/nrc2126openalex-snapshot
Second generation inhibitors of BCR-ABL for the treatment of imatinib-resistant chronic myeloid leukaemia
inferredcites →https://doi.org/10.1038/nrc2728openalex-snapshot
p53 — a Jack of all trades but master of none
inferredcites →https://doi.org/10.1038/nrm1280openalex-snapshot
Regulation of the c-Abl and Bcr–Abl tyrosine kinases
inferredcites →https://doi.org/10.1038/nrm2395openalex-snapshot
Transcriptional control of human p53-regulated genes
inferredcites →https://doi.org/10.1038/sj.cdd.4400626openalex-snapshot
c-Abl: activation and nuclear targets
inferredcites →https://doi.org/10.1038/sj.cdd.4401539openalex-snapshot
C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage
inferredcites →https://doi.org/10.1038/sj.cr.7290261openalex-snapshot
Role of c-Abl in the DNA damage stress response
inferredcites →https://doi.org/10.1038/sj.emboj.7601263openalex-snapshot
MUC1 oncoprotein blocks nuclear targeting of c‐Abl in the apoptotic response to DNA damage
inferredcites →https://doi.org/10.1038/sj.onc.1201934openalex-snapshot
Functional role for the c-Abl tyrosine kinase in meiosis I
inferredcites →https://doi.org/10.1038/sj.onc.1202276openalex-snapshot
ASK1 mediates apoptotic cell death induced by genotoxic stress
inferredcites →https://doi.org/10.1038/sj.onc.1203878openalex-snapshot
Regulation of cell death by the Abl tyrosine kinase
inferredcites →https://doi.org/10.1038/sj.onc.1208332openalex-snapshot
The life and death of DNA-PK
inferredcites →https://doi.org/10.1042/0300-5127:0290666openalex-snapshot
Choosing between growth arrest and apoptosis through the retinoblastoma tumour suppressor protein, Abl and p73
inferredcites →https://doi.org/10.1042/bc20080020openalex-snapshot
Cytoplasmic signalling by the c‐Abl tyrosine kinase in normal and cancer cells
inferredcites →https://doi.org/10.1042/bj20061778openalex-snapshot
Regulation of p73-mediated apoptosis by c-Jun N-terminal kinase
inferredcites →https://doi.org/10.1056/nejmra043475openalex-snapshot
Potential Options for Preservation of Fertility in Women
inferredcites →https://doi.org/10.1056/nejmra0801454openalex-snapshot
Preservation of Fertility in Patients with Cancer
inferredcites →https://doi.org/10.1073/pnas.0736384100openalex-snapshot
Drosophila p53 preserves genomic stability by regulating cell death
inferredcites →https://doi.org/10.1073/pnas.78.11.6789openalex-snapshot
DNA sequences homologous to vertebrate oncogenes are conserved in Drosophila melanogaster.
inferredcites →https://doi.org/10.1073/pnas.83.7.2172openalex-snapshot
Isolation and characterization of Caenorhabditis elegans DNA sequences homologous to the v-abl oncogene.
inferredcites →https://doi.org/10.1073/pnas.84.23.8200openalex-snapshot
Nucleotide sequence of testis-derived c-abl cDNAs: implications for testis-specific transcription and abl oncogene activation.
inferredcites →https://doi.org/10.1073/pnas.95.13.7457openalex-snapshot
Nuclear-cytoplasmic shuttling of C-ABL tyrosine kinase
inferredcites →https://doi.org/10.1074/jbc.273.7.3799openalex-snapshot
Regulation of Rad51 Function by c-Abl in Response to DNA Damage
inferredcites →https://doi.org/10.1074/jbc.274.18.12748openalex-snapshot
Radiation-induced Assembly of Rad51 and Rad52 Recombination Complex Requires ATM and c-Abl
inferredcites →https://doi.org/10.1074/jbc.275.2.725openalex-snapshot
c-Abl Tyrosine Kinase Is Not Essential for Ataxia Telangiectasia Mutated Functions in Chromosomal Maintenance
inferredcites →https://doi.org/10.1074/jbc.m109.078436openalex-snapshot
MRE11-RAD50-NBS1 Complex Dictates DNA Repair Independent of H2AX
inferredcites →https://doi.org/10.1074/jbc.m204416200openalex-snapshot
Interaction between UV-damaged DNA Binding Activity Proteins and the c-Abl Tyrosine Kinase
inferredcites →https://doi.org/10.1074/jbc.m208151200openalex-snapshot
Regulation of Ionizing Radiation-induced Rad52 Nuclear Foci Formation by c-Abl-mediated Phosphorylation
inferredcites →https://doi.org/10.1083/jcb.146.5.905openalex-snapshot
Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo
inferredcites →https://doi.org/10.1093/emboj/16.2.430openalex-snapshot
DNA double‐strand breaks caused by replication arrest
inferredcites →https://doi.org/10.1093/emboj/16.24.7261openalex-snapshot
The role of the linker between the SH2 domain and catalytic domain in the regulation and function of Src
inferredcites →https://doi.org/10.1093/emboj/cdf384openalex-snapshot
Tyrosine phosphorylation of Mdm2 by c‐Abl: implications for p53 regulation
inferredcites →https://doi.org/10.1093/emboj/cdg541openalex-snapshot
Requirement of the MRN complex for ATM activation by DNA damage
inferredcites →https://doi.org/10.1093/emboj/cdg630openalex-snapshot
The Mre11 complex is required for ATM activation and the G2/M checkpoint
inferredcites →https://doi.org/10.1093/jn/137.6.1518sopenalex-snapshot
c-Abl Tyrosine Kinase and Inhibition by the Cancer Drug Imatinib (Gleevec/STI-571)
inferredcites →https://doi.org/10.1097/gco.0b013e32831e13b9openalex-snapshot
Techniques for fertility preservation in patients with breast cancer
inferredcites →https://doi.org/10.1101/cshperspect.a001131openalex-snapshot
Phylogeny and Function of the Invertebrate p53 Superfamily
inferredcites →https://doi.org/10.1101/cshperspect.a001198openalex-snapshot
The Origins and Evolution of the p53 Family of Genes
inferredcites →https://doi.org/10.1101/gad.10.9.1054openalex-snapshot
p53: puzzle and paradigm.
inferredcites →https://doi.org/10.1101/gad.1339905openalex-snapshot
p53 isoforms can regulate p53 transcriptional activity
inferredcites →https://doi.org/10.1101/gad.14.9.1085openalex-snapshot
MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice
inferredcites →https://doi.org/10.1111/j.1600-065x.2008.00751.xopenalex-snapshot
Abl tyrosine kinases in T‐cell signaling
inferredcites →https://doi.org/10.1126/science.1065486openalex-snapshot
Caenorhabditis elegans p53: Role in Apoptosis, Meiosis, and Stress Resistance
inferredcites →https://doi.org/10.1126/science.1108297openalex-snapshot
ATM Activation by DNA Double-Strand Breaks Through the Mre11-Rad50-Nbs1 Complex
inferredcites →https://doi.org/10.1126/science.289.5486.1938openalex-snapshot
Structural Mechanism for STI-571 Inhibition of Abelson Tyrosine Kinase
inferredcites →https://doi.org/10.1126/science.3291120openalex-snapshot
The RAD9 Gene Controls the Cell Cycle Response to DNA Damage in Saccharomyces cerevisiae
inferredcites →https://doi.org/10.1128/mcb.22.12.4020-4032.2002openalex-snapshot
Constitutive Association of BRCA1 and c-Abl and Its ATM-Dependent Disruption after Irradiation
inferredcites →https://doi.org/10.1128/mcb.24.3.1219-1231.2004openalex-snapshot
Drosophila melanogaster MNK/Chk2 and p53 Regulate Multiple DNA Repair and Apoptotic Pathways following DNA Damage
inferredcites →https://doi.org/10.1128/mcb.3.5.773openalex-snapshot
Cellular RNA Homologous to the Abelson Murine Leukemia Virus Transforming Gene: Expression and Relationship to the Viral Sequence
inferredcites →https://doi.org/10.1128/mcb.4.5.982openalex-snapshot
Expression of the src and abl cellular oncogenes during development of Drosophila melanogaster.
inferredcites →https://doi.org/10.1128/mcb.5.7.1791openalex-snapshot
Haploid expression of a unique c-abl transcript in the mouse male germ line.
inferredcites →https://doi.org/10.1146/annurev.biochem.71.090501.150203openalex-snapshot
V(D)J Recombination: RAG Proteins, Repair Factors, and Regulation
inferredcites →https://doi.org/10.1158/0008-5472.can-05-3019openalex-snapshot
Physical and Functional Interaction between hMSH5 and c-Abl
inferredcites →https://doi.org/10.1186/bcr1991openalex-snapshot
Cancer and fertility preservation: fertility preservation in breast cancer patients
inferredcites →https://doi.org/10.1530/eje-07-0400openalex-snapshot
Genetic investigation of four meiotic genes in women with premature ovarian failure
inferredcites →https://doi.org/10.2741/2112openalex-snapshot
MutS Homologues hMSH4 and hMSH5: Diverse Functional Implications in Humans
inferredcites →https://doi.org/10.4161/cc.9.2.10563openalex-snapshot
Modulating c-Abl nuclear activity as a strategy to preserve female fertility

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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The Abl1 Tyrosine Kinase and p53 are Key Players in Doxorubicin-Induced Cardiomyopathy and Their Cell Death Signaling Differs in Atrial and Ventricular Cardiomyocytes
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The genetics of chronic myelogenous leukaemia
inferred← citeshttps://doi.org/10.1002/humu.23744openalex-snapshot
TP63‐truncating variants cause isolated premature ovarian insufficiency
inferred← citeshttps://doi.org/10.1007/978-981-19-8848-6_4openalex-snapshot
Ovarian Aging Etiology and Risk Factors
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Dose-dependent effects of ghrelin and aberrant anti-Mullerian hormone levels in the prevention of ovarian damage caused by cisplatin in Wistar-albino rats
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Fertility Preservation
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Fertility Preservation
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Impaired steroidogenesis and apoptosis of granulosa-luteal cells in primary culture induced by cis-platinum
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DNA damage response: The emerging role of c-Abl as a regulatory switch?
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Proteomic-based identification of Apg-2 as a therapeutic target for chronic myeloid leukemia
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Topology and dynamics of the interaction between 5-nitroimidazole radiosensitizers and duplex DNA studied by a combination of docking, molecular dynamic simulations and NMR spectroscopy
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Targeting DNA damage response: Threshold, chromatin landscape and beyond
inferred← citeshttps://doi.org/10.1016/j.repbio.2016.11.003openalex-snapshot
Developmental effects of imatinib mesylate on follicle assembly and early activation of primordial follicle pool in postnatal rat ovary
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Determination of c-Abl tyrosine kinase and mTERT catalytic subunit of telomerase expression level during prenatal-postnatal mouse ovary-testis development
inferred← citeshttps://doi.org/10.1016/j.trecan.2015.07.004openalex-snapshot
The Emerging Role of ABL Kinases in Solid Tumors
inferred← citeshttps://doi.org/10.1038/s41418-018-0151-2openalex-snapshot
Transient inhibition of p53 homologs protects ovarian function from two distinct apoptotic pathways triggered by anticancer therapies
inferred← citeshttps://doi.org/10.1038/s41598-024-77032-2openalex-snapshot
Flavopiridol induces cell cycle arrest and apoptosis by interfering with CDK1 signaling pathway in human ovarian granulosa cells
inferred← citeshttps://doi.org/10.1093/humupd/dms022openalex-snapshot
How do chemotherapeutic agents damage the ovary?
inferred← citeshttps://doi.org/10.1111/andr.12803openalex-snapshot
Association of hMSH5 C85T polymorphism with radiation sensitivity of testicular cell lines GC‐1, GC‐2, TM3, and TM4
inferred← citeshttps://doi.org/10.1186/1476-4598-10-88openalex-snapshot
Tip60-mediated acetylation activates transcription independent apoptotic activity of Abl
inferred← citeshttps://doi.org/10.1186/s12958-024-01273-zopenalex-snapshot
Molecular regulation of DNA damage and repair in female infertility: a systematic review
inferred← citeshttps://doi.org/10.1186/s12967-024-05623-8openalex-snapshot
The Abl1 tyrosine kinase is a key player in doxorubicin-induced cardiomyopathy and its p53/p73 cell death mediated signaling differs in atrial and ventricular cardiomyocytes
inferred← citeshttps://doi.org/10.1186/s13048-025-01950-6openalex-snapshot
Fertility under fire: how chemotherapy harms the ovaries and the science fighting back?
inferred← citeshttps://doi.org/10.1371/journal.pone.0046185openalex-snapshot
c-Abl Inhibition Delays Motor Neuron Degeneration in the G93A Mouse, an Animal Model of Amyotrophic Lateral Sclerosis
inferred← citeshttps://doi.org/10.1371/journal.pone.0070117openalex-snapshot
Cisplatin and Doxorubicin Induce Distinct Mechanisms of Ovarian Follicle Loss; Imatinib Provides Selective Protection Only against Cisplatin
inferred← citeshttps://doi.org/10.1517/14728222.2012.668185openalex-snapshot
14-3-3 zeta as novel molecular target for cancer therapy
inferred← citeshttps://doi.org/10.1530/rep-19-0279openalex-snapshot
Single and combined effects of cisplatin and doxorubicin on the human and mouse ovary in vitro
inferred← citeshttps://doi.org/10.21203/rs.3.rs-4167568/v1openalex-snapshot
Flavopiridol induces cell cycle arrest and apoptosis by interfering with CDK1 signaling pathway and inducing excessive reactive oxygen species in human ovarian granulosa cells
inferred← citeshttps://doi.org/10.3164/jcbn.11-109openalex-snapshot
Novel roles of peroxiredoxins in inflammation, cancer and innate immunity
inferred← citeshttps://doi.org/10.3390/cancers16122288openalex-snapshot
Gynotoxic Effects of Chemotherapy and Potential Protective Mechanisms
inferred← citeshttps://doi.org/10.3390/ijms14022388openalex-snapshot
Parkinson’s Disease: A Complex Interplay of Mitochondrial DNA Alterations and Oxidative Stress
inferred← citeshttps://doi.org/10.33915/etd.472openalex-snapshot
Abelson Kinase Based Regulation of Tumor Cell Invasion in HNSCC
inferred← citeshttps://doi.org/10.3892/mmr.2020.11156openalex-snapshot
c‑Abl‑mediated tyrosine phosphorylation of DNA damage response proteins and implications in important cellular functions (Review)
inferred← citeshttps://doi.org/10.4274/imj.galenos.2020.46667openalex-snapshot
Protective Effects of Imatinib and Ginkgo Biloba on Cisplatin-induced Ovarian Damage in Rats
inferred← citeshttps://doi.org/10.5653/cerm.2020.04049openalex-snapshot
The role of gonadotropin-releasing hormone agonists in female fertility preservation
inferred← citeshttps://doi.org/10.5772/53532openalex-snapshot
DNA Repair Molecules and Cancer Therapeutical Responses
inferred← citeshttps://doi.org/10.58600/eurjther3044openalex-snapshot
Effects of Boric Acid on ABL1 Gene Expression in Swiss Albino Mice Exposed to High-Dose Total Body Irradiation
inferred← citeshttps://doi.org/10.64898/2026.04.17.719163openalex-snapshot
HIPK2-and IKKβ-dependent phosphorylation stabilizes TAp63α during the oocyte DNA damage response
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