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Application of droplet digital PCR to detect the pathogens of infectious diseases

https://doi.org/10.1042/bsr20181170

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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inferredcites →https://doi.org/10.1128/jcm.33.2.419-427.1995openalex-snapshot

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inferredcites →https://doi.org/10.1128/jcm.42.12.5636-5643.2004openalex-snapshot

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inferred← citeshttps://doi.org/10.1038/s41598-024-81682-7openalex-snapshot

Ultrasensitive detection and quantification of bovine Deltapapillomavirus in the semen of healthy horses

inferred← citeshttps://doi.org/10.1038/s41598-025-15353-6openalex-snapshot

Accurate identification of bovine deltapapillomavirus in equine sarcoids by ddPCR

inferred← citeshttps://doi.org/10.1038/s41598-025-94279-5openalex-snapshot

Digital droplet PCR-based detection and quantification of ovine papillomavirus DNA from the vaginal virobiota of healthy mares

inferred← citeshttps://doi.org/10.1038/s41598-026-52384-zopenalex-snapshot

Detection of papillomavirus DNA in uterine flushing samples from healthy mares reveals diverse genotypes with differing host ranges

inferred← citeshttps://doi.org/10.1039/c9an01316dopenalex-snapshot

Epigenetic subtyping of white blood cells using a thermoplastic elastomer-based microfluidic emulsification device for multiplexed, methylation-specific digital droplet PCR

inferred← citeshttps://doi.org/10.1039/d3ay01906copenalex-snapshot

Establishment of reference measurement procedure and reference material for Treponema pallidum

inferred← citeshttps://doi.org/10.1039/d3lc00482aopenalex-snapshot

Micro- and nanosystems for the detection of hemorrhagic fever viruses

inferred← citeshttps://doi.org/10.1039/d4ay01147copenalex-snapshot

Recent advances in the CRISPR/Cas system-based visual detection method

inferred← citeshttps://doi.org/10.1039/d4lc00117fopenalex-snapshot

Microfluidic systems for infectious disease diagnostics

inferred← citeshttps://doi.org/10.1063/5.0159016openalex-snapshot

Research on accurate pipetting complementation model for high-throughput molecular detection platform

inferred← citeshttps://doi.org/10.1063/5.0180394openalex-snapshot

Manually pressurized droplet digital PCR chip for rapid SARS-CoV-2 diagnostics

inferred← citeshttps://doi.org/10.1080/01652176.2024.2387072openalex-snapshot

Molecular findings and virological assessment of bladder papillomavirus infection in cattle

inferred← citeshttps://doi.org/10.1080/01652176.2024.2390944openalex-snapshot

Detection and quantification of Brucella abortus DNA in water buffaloes ( bubalus bubalis ) using droplet digital polymerase chain reaction

inferred← citeshttps://doi.org/10.1080/1040841x.2022.2125287openalex-snapshot

Advances on diagnosis of Helicobacter pylori infections

inferred← citeshttps://doi.org/10.1080/10826068.2022.2137731openalex-snapshot

Cost-effective, high-yield production of Pyrobaculum calidifontis DNA polymerase for PCR application

inferred← citeshttps://doi.org/10.1089/fpd.2020.2865openalex-snapshot

Rapid Identification of Plasmid Replicon Type and Coexisting Plasmid-Borne Antimicrobial Resistance Genes by S1-Pulsed-Field Gel Electrophoresis-Droplet Digital Polymerase Chain Reaction

inferred← citeshttps://doi.org/10.1094/pdis-03-23-0439-sropenalex-snapshot

Development of a Droplet Digital PCR Assay for Detection and Quantification of Stubby Root Nematode, Paratrichodorus allius, in Soil

inferred← citeshttps://doi.org/10.1097/id9.0000000000000166openalex-snapshot

A survey of SARS-CoV-2 tropism

inferred← citeshttps://doi.org/10.1101/2020.02.25.963975openalex-snapshot

A liquid biopsy platform for detecting gene-gene fusions as glioma diagnostic biomarkers and drug targets

inferred← citeshttps://doi.org/10.1101/2020.07.03.186304openalex-snapshot

Robust and sensitive detection of SARS-CoV-2 using PCR based methods

inferred← citeshttps://doi.org/10.1108/rpj-05-2024-0215openalex-snapshot

A 3D printed microfluidic device for centrifugal droplet generation

inferred← citeshttps://doi.org/10.1111/1541-4337.12579openalex-snapshot

Comparative review and the recent progress in detection technologies of meat product adulteration

inferred← citeshttps://doi.org/10.1111/1751-7915.13491openalex-snapshot

Droplet digital polymerase chain reaction for rapid broad‐spectrum detection of bloodstream infections

inferred← citeshttps://doi.org/10.1111/jfd.13844openalex-snapshot

Development of a droplet digital PCR assay for the sensitive detection of iridovirus in Andrias davidianus

inferred← citeshttps://doi.org/10.1111/jfd.14019openalex-snapshot

Droplet digital PCR for fish pathogen detection and quantification: A systematic review and meta‐analysis

inferred← citeshttps://doi.org/10.1111/tbed.13971openalex-snapshot

The diagnostic value of the droplet digital PCR for the detection of bovine deltapapillomavirus in goats by liquid biopsy

inferred← citeshttps://doi.org/10.1111/zph.12883openalex-snapshot

Detection of Anaplasma phagocytophilum in European brown hares (Lepus europaeus) using three different methods

inferred← citeshttps://doi.org/10.1128/aem.00557-24openalex-snapshot

Multiple factors trigger the formation and resuscitation of the VBNC state in alcohol-producing Klebsiella pneumoniae

inferred← citeshttps://doi.org/10.1128/cmr.00018-19openalex-snapshot

Laboratory Diagnosis of Lyme Borreliosis

inferred← citeshttps://doi.org/10.1128/cmr.00168-21openalex-snapshot

Digital PCR Applications in the SARS-CoV-2/COVID-19 Era: a Roadmap for Future Outbreaks

inferred← citeshttps://doi.org/10.1128/jcm.00367-26openalex-snapshot

Droplet digital PCR-based nucleic acid amplification test for improved molecular and clinical diagnosis of severe fever with thrombocytopenia syndrome patients

inferred← citeshttps://doi.org/10.1128/spectrum.00249-24openalex-snapshot

Quantitative detection and survival analysis of VBNC Salmonella Typhimurium in flour using droplet digital PCR and DNA-intercalating dyes

inferred← citeshttps://doi.org/10.1128/spectrum.01378-22openalex-snapshot

Clinical Diagnostic Performance of Droplet Digital PCR for Suspected Bloodstream Infections

inferred← citeshttps://doi.org/10.1128/spectrum.02522-25openalex-snapshot

Development of a droplet digital PCR for detection and quantitation of human parvovirus B19

inferred← citeshttps://doi.org/10.1128/spectrum.02548-25openalex-snapshot

A novel five-plex digital PCR assay for the simultaneous detection of murine pathogens: Sendai virus, reovirus, mouse parvoviruses, pneumonia virus of mice, and mouse hepatitis virus

inferred← citeshttps://doi.org/10.1128/spectrum.04249-22openalex-snapshot

Detection and Quantification of Klebsiella pneumoniae in Fecal Samples Using Digital Droplet PCR in Comparison with Real-Time PCR

inferred← citeshttps://doi.org/10.1155/2021/1535046openalex-snapshot

Susceptible-Infected-Removed Mathematical Model under Deep Learning in Hospital Infection Control of Novel Coronavirus Pneumonia

inferred← citeshttps://doi.org/10.1177/1040638719890863openalex-snapshot

Development of a high-throughput real-time PCR system for detection of enzootic pathogens in pigs

inferred← citeshttps://doi.org/10.1186/s12879-022-07557-2openalex-snapshot

Evaluation of droplet digital PCR rapid detection method and precise diagnosis and treatment for suspected sepsis (PROGRESS): a study protocol for a multi-center pragmatic randomized controlled trial

inferred← citeshttps://doi.org/10.1186/s12879-023-08580-7openalex-snapshot

Relationship between clinical features and droplet digital PCR copy number in non-HIV patients with pneumocystis pneumonia

inferred← citeshttps://doi.org/10.1186/s12985-022-01798-yopenalex-snapshot

Development of a multiplex droplet digital PCR assay for detection of enterovirus, parechovirus, herpes simplex virus 1 and 2 simultaneously for diagnosis of viral CNS infections

inferred← citeshttps://doi.org/10.1186/s13071-023-05756-7openalex-snapshot

Digital PCR: modern solution to parasite diagnostics and population trait genetics

inferred← citeshttps://doi.org/10.1186/s13071-025-06871-3openalex-snapshot

Development of a novel ddPCR assay for the simultaneous detection of the protozoan parasites Leishmania infantum and Leishmania tarentolae

inferred← citeshttps://doi.org/10.1186/s40001-026-03857-4openalex-snapshot

Diagnostic advantage of droplet digital PCR over blood culture in sepsis: a retrospective study of 115 patients

inferred← citeshttps://doi.org/10.1371/journal.pntd.0011367openalex-snapshot

Development and evaluation of a droplet digital PCR assay to detect Brucella in human whole blood

inferred← citeshttps://doi.org/10.1371/journal.pone.0220908openalex-snapshot

Clinical correlation of influenza and respiratory syncytial virus load measured by digital PCR

inferred← citeshttps://doi.org/10.1371/journal.pone.0291947openalex-snapshot

A targeted amplicon next-generation sequencing assay for tryptase genotyping to support personalized therapy in mast cell-related disorders

inferred← citeshttps://doi.org/10.1373/clinchem.2019.304048openalex-snapshot

Digital PCR—An Emerging Technology with Broad Applications in Microbiology

inferred← citeshttps://doi.org/10.1515/abm-2019-0063openalex-snapshot

Update on molecular diagnosis of human leptospirosis

inferred← citeshttps://doi.org/10.1590/1414-431x2023e12894openalex-snapshot

Unlocking the molecular realm: advanced approaches for identifying clinically and environmentally relevant bacteria

inferred← citeshttps://doi.org/10.17235/reed.2025.11226/2025openalex-snapshot

Serum HBV RNA as a Predictive Biomarker for HBeAg Seroconversion During Entecavir and Tenofovir Disoproxil Fumarate Therapy in Chronic Hepatitis B Patients

inferred← citeshttps://doi.org/10.21037/atm-22-3818openalex-snapshot

Screening of plasma exosomal lncRNAs to identify potential biomarkers for obstructive sleep apnea

inferred← citeshttps://doi.org/10.21203/rs.3.rs-2237837/v1openalex-snapshot

TERT promoter mutation predicts the prognosis value of patients with HBV- related HCC who underwent hepatectomy

inferred← citeshttps://doi.org/10.2144/btn-2020-0133openalex-snapshot

Increased Sensitivity Using Real-Time dPCR for Detection of SARS-CoV-2

inferred← citeshttps://doi.org/10.2147/idr.s349607openalex-snapshot

Application of Droplet Digital PCR to Detection of Mycobacterium tuberculosis and Mycobacterium leprae Infections: A Narrative Review

inferred← citeshttps://doi.org/10.2147/idr.s570142openalex-snapshot

Diagnostic Performance of Droplet Digital PCR for Detecting Pathogens and Resistance Genes in Patients with Suspected Bloodstream Infections

inferred← citeshttps://doi.org/10.2147/idr.s602270openalex-snapshot

A High Sensitive Detection of Droplet Digital PCR for the Diagnosis of Pulmonary Tuberculosis

inferred← citeshttps://doi.org/10.2166/ws.2021.056openalex-snapshot

The detection efficiency of digital PCR for the virulence genes of waterborne pathogenic bacteria

inferred← citeshttps://doi.org/10.2174/0113816128276560231218090436openalex-snapshot

The Significance and Importance of dPCR, qPCR, and SYBR Green PCR Kit in the Detection of Numerous Diseases

inferred← citeshttps://doi.org/10.2174/0113816128298998240828060306openalex-snapshot

Inhibition of Colorectal Cancer Metastasis by Total Flavones of Abelmoschus manihot via LncRNA AL137782-mediated STAT3/EMT Pathway Regulation

inferred← citeshttps://doi.org/10.2217/fvl-2023-0143openalex-snapshot

Trends and Perspectives in Tuberculosis and HIV Co-Infection Studies Over the Past Three Decades

inferred← citeshttps://doi.org/10.33160/yam.2026.08.005openalex-snapshot

Molecular Diagnostics of Infectious Diseases

inferred← citeshttps://doi.org/10.3389/fcimb.2021.685640openalex-snapshot

Assessment of the Diagnostic Ability of Four Detection Methods Using Three Sample Types of COVID-19 Patients

inferred← citeshttps://doi.org/10.3389/fcimb.2021.753078openalex-snapshot

Enumeration of Viable Non-Culturable Vibrio cholerae Using Droplet Digital PCR Combined With Propidium Monoazide Treatment

inferred← citeshttps://doi.org/10.3389/fcimb.2023.1301446openalex-snapshot

Development of droplet digital PCR-based detection of bacterial pathogens in prosthetic joint infection: a preliminary study using a synthesized model plasmid

inferred← citeshttps://doi.org/10.3389/fcimb.2025.1627943openalex-snapshot

Absolute quantification of VBNC state formation and resuscitation in alcohol-producing Klebsiella pneumoniae

inferred← citeshttps://doi.org/10.3389/fcimb.2026.1701517openalex-snapshot

Development of a novel duplex crystal digital PCR for the detection of PRRSV–1 and PRRSV–2

inferred← citeshttps://doi.org/10.3389/fimmu.2022.911873openalex-snapshot

A robust experimental and computational analysis framework at multiple resolutions, modalities and coverages

inferred← citeshttps://doi.org/10.3389/fimmu.2026.1811554openalex-snapshot

From forest floor to doctor’s office: the immunological journey of Borrelia burgdorferi through vertebrate hosts

inferred← citeshttps://doi.org/10.3389/fmed.2023.1248842openalex-snapshot

Droplet digital PCR vs. quantitative real time-PCR for diagnosis of pulmonary and extrapulmonary tuberculosis: systematic review and meta-analysis

inferred← citeshttps://doi.org/10.3389/fmicb.2021.641202openalex-snapshot

A Comparison of Blood Pathogen Detection Among Droplet Digital PCR, Metagenomic Next-Generation Sequencing, and Blood Culture in Critically Ill Patients With Suspected Bloodstream Infections

inferred← citeshttps://doi.org/10.3389/fmicb.2021.747560openalex-snapshot

A Duplex-Droplet Digital PCR Assay for Simultaneous Quantitative Detection of Monilinia fructicola and Monilinia laxa on Stone Fruits

inferred← citeshttps://doi.org/10.3389/fmicb.2022.1019876openalex-snapshot

Advances in the differential molecular diagnosis of vesicular disease pathogens in swine

inferred← citeshttps://doi.org/10.3389/fmicb.2023.1149981openalex-snapshot

Absolute quantification of viable Vibrio cholerae in seawater samples using multiplex droplet digital PCR combined with propidium monoazide

inferred← citeshttps://doi.org/10.3389/fmicb.2023.1177273openalex-snapshot

Absolute quantification of Mycoplasma pneumoniae in infected patients by droplet digital PCR to track disease severity and treatment efficacy

inferred← citeshttps://doi.org/10.3389/fmicb.2024.1397792openalex-snapshot

Development and evaluation of a triplex droplet digital PCR method for differentiation of M. tuberculosis, M. bovis and BCG

inferred← citeshttps://doi.org/10.3389/fmicb.2025.1710807openalex-snapshot

Development and validation of a novel triplex droplet digital PCR assay for simultaneous detection of African swine fever virus, pseudorabies virus, and porcine parvovirus

inferred← citeshttps://doi.org/10.3389/fmicb.2026.1791178openalex-snapshot

Wastewater genomic surveillance identifies the emergence of the SARS-CoV-2 JN.1 lineage in urban settings of Gujarat

inferred← citeshttps://doi.org/10.3389/fonc.2022.864820openalex-snapshot

Molecular Detection Methods in HPV-Related Cancers

inferred← citeshttps://doi.org/10.3389/fphar.2020.00486openalex-snapshot

Long-Distance Phasing of a Tentative “Enhancer” Single-Nucleotide Polymorphism With CYP2D6 Star Allele Definitions

inferred← citeshttps://doi.org/10.3389/fpls.2023.1106784openalex-snapshot

Current advances in the identification of plant nematode diseases: From lab assays to in-field diagnostics

inferred← citeshttps://doi.org/10.3389/fpubh.2023.1340420openalex-snapshot

Ready for new waves: optimizing SARS-CoV-2 variants monitoring in pooled samples with droplet digital PCR

inferred← citeshttps://doi.org/10.3389/fvets.2021.790392openalex-snapshot

Molecular Epidemiology of Ovine Papillomavirus Infections Among Sheep in Southern Italy

inferred← citeshttps://doi.org/10.3389/fvets.2024.1427370openalex-snapshot

Molecular detection of transcriptionally active ovine papillomaviruses in commercial equine semen

inferred← citeshttps://doi.org/10.3389/fvets.2024.1462880openalex-snapshot

Development of a triplex crystal digital RT-PCR for the detection of PHEV, PRV, and CSFV

inferred← citeshttps://doi.org/10.3389/fvets.2025.1562444openalex-snapshot

Development of a triplex crystal digital PCR for the detection of PRCoV, PRRSV, and SIV

inferred← citeshttps://doi.org/10.3390/agriculture13030716openalex-snapshot

Detection of Xylella fastidiosa in Host Plants and Insect Vectors by Droplet Digital PCR

inferred← citeshttps://doi.org/10.3390/ani11051270openalex-snapshot

Droplet Digital PCR (ddPCR) Analysis for the Detection and Quantification of Cow DNA in Buffalo Mozzarella Cheese

inferred← citeshttps://doi.org/10.3390/antibiotics10111362openalex-snapshot

Wastewater-Based Surveillance of Antibiotic Resistance Genes Associated with Tuberculosis Treatment Regimen in KwaZulu Natal, South Africa

inferred← citeshttps://doi.org/10.3390/antibiotics11040511openalex-snapshot

Diagnosis of Bloodstream Infections: An Evolution of Technologies towards Accurate and Rapid Identification and Antibiotic Susceptibility Testing

inferred← citeshttps://doi.org/10.3390/antibiotics9120916openalex-snapshot

Developing Diagnostic and Therapeutic Approaches to Bacterial Infections for a New Era: Implications of Globalization

inferred← citeshttps://doi.org/10.3390/app12073654openalex-snapshot

Droplet Digital PCR (ddPCR) Analysis for Detecting Shiga-Toxin-Producing Escherichia coli (STEC)

inferred← citeshttps://doi.org/10.3390/biomedicines11051306openalex-snapshot

HIV-HBV Coinfection—Current Challenges for Virologic Monitoring

inferred← citeshttps://doi.org/10.3390/bios12100869openalex-snapshot

Recent Progress in Spectroscopic Methods for the Detection of Foodborne Pathogenic Bacteria

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