On the public citation graph

E2 Ubiquitin-conjugating Enzyme, UBE2C Gene, Is Reciprocally Regulated by Wild-type and Gain-of-Function Mutant p53

0 signed · 87 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.
Claim with ORCID
Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.
See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1006/bbrc.2001.5040openalex-snapshot
Expression of the Cell Cycle Phosphatase cdc25C Is Down-Regulated by the Tumor Suppressor Protein p53 but Not by p73
inferredcites →https://doi.org/10.1016/j.ccr.2006.08.013openalex-snapshot
Gain of function of mutant p53: The mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation
inferredcites →https://doi.org/10.1016/j.cell.2009.04.037openalex-snapshot
Blinded by the Light: The Growing Complexity of p53
inferredcites →https://doi.org/10.1016/s0014-5793(00)01363-6openalex-snapshot
A CDE/CHR‐like element mediates repression of transcription of the mouse RB2 (p130) gene
inferredcites →https://doi.org/10.1016/s0014-5793(00)02133-5openalex-snapshot
A CDE/CHR tandem element regulates cell cycle‐dependent repression of cyclin B2 transcription
inferredcites →https://doi.org/10.1016/s0955-0674(96)80077-9openalex-snapshot
The spindle assembly checkpoint
inferredcites →https://doi.org/10.1016/s0960-9822(02)00513-4openalex-snapshot
Identification of a novel ubiquitin-conjugating enzyme involved in mitotic cyclin degradation
inferredcites →https://doi.org/10.1016/s1476-5586(04)80047-2openalex-snapshot
ONCOMINE: A Cancer Microarray Database and Integrated Data-Mining Platform
inferredcites →https://doi.org/10.1038/cdd.2015.133openalex-snapshot
DNA damage-induced ephrin-B2 reverse signaling promotes chemoresistance and drives EMT in colorectal carcinoma harboring mutant p53
inferredcites →https://doi.org/10.1038/emboj.2009.186openalex-snapshot
A quantitative systems view of the spindle assembly checkpoint
inferredcites →https://doi.org/10.1038/msb4100030openalex-snapshot
The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation
inferredcites →https://doi.org/10.1038/nature05694openalex-snapshot
Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities
inferredcites →https://doi.org/10.1038/nature05734openalex-snapshot
Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation
inferredcites →https://doi.org/10.1038/ng1861openalex-snapshot
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
inferredcites →https://doi.org/10.1038/nm0796-811openalex-snapshot
Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients
inferredcites →https://doi.org/10.1038/nrc2696openalex-snapshot
Emerging roles of E2Fs in cancer: an exit from cell cycle control
inferredcites →https://doi.org/10.1038/nrc2718openalex-snapshot
p53 and E2f: partners in life and death
inferredcites →https://doi.org/10.1038/nrc2723openalex-snapshot
The first 30 years of p53: growing ever more complex
inferredcites →https://doi.org/10.1038/nrm2147openalex-snapshot
p53 in health and disease
inferredcites →https://doi.org/10.1038/sj.bjc.6602721openalex-snapshot
UbcH10 overexpression may represent a marker of anaplastic thyroid carcinomas
inferredcites →https://doi.org/10.1038/sj.onc.1202129openalex-snapshot
EWS/FLI1 up regulates mE2-C, a cyclin-selective ubiquitin conjugating enzyme involved in cyclin B destruction
inferredcites →https://doi.org/10.1038/sj.onc.1202314openalex-snapshot
Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy
inferredcites →https://doi.org/10.1038/sj.onc.1204319openalex-snapshot
DNA microarrays identification of primary and secondary target genes regulated by p53
inferredcites →https://doi.org/10.1038/sj.onc.1207482openalex-snapshot
Cdk2-dependent phosphorylation of the NF-Y transcription factor is essential for the expression of the cell cycle-regulatory genes and cell cycle G1/S and G2/M transitions
inferredcites →https://doi.org/10.1038/sj.onc.1207860openalex-snapshot
Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy
inferredcites →https://doi.org/10.1038/sj.onc.1209276openalex-snapshot
Induction of tetraploidy through loss of p53 and upregulation of Plk1 by human papillomavirus type-16 E6
inferredcites →https://doi.org/10.1038/sj.onc.1210010openalex-snapshot
UbcH10 expression may be a useful tool in the prognosis of ovarian carcinomas
inferredcites →https://doi.org/10.1038/sj.onc.1210294openalex-snapshot
Transcription regulation by mutant p53
inferredcites →https://doi.org/10.1073/pnas.94.7.2776openalex-snapshot
The cell cycle and cancer
inferredcites →https://doi.org/10.1074/jbc.m005101200openalex-snapshot
p130/E2F4 Binds to and Represses the cdc2 Promoter in Response to p53
inferredcites →https://doi.org/10.1074/jbc.m106643200openalex-snapshot
Transcriptional Repression of the Anti-apoptoticsurvivin Gene by Wild Type p53
inferredcites →https://doi.org/10.1074/jbc.m110.160671openalex-snapshot
Spindle Assembly Checkpoint Protein Cdc20 Transcriptionally Activates Expression of Ubiquitin Carrier Protein UbcH10
inferredcites →https://doi.org/10.1074/jbc.m212517200openalex-snapshot
p21/CDKN1A Mediates Negative Regulation of Transcription by p53
inferredcites →https://doi.org/10.1074/jbc.m307185200openalex-snapshot
Transcriptional Regulation of Mitotic Checkpoint Gene MAD1 by p53
inferredcites →https://doi.org/10.1074/jbc.m513901200openalex-snapshot
Identification of Cell Cycle Regulatory Genes as Principal Targets of p53-mediated Transcriptional Repression
inferredcites →https://doi.org/10.1083/jcb.127.5.1301openalex-snapshot
Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle.
inferredcites →https://doi.org/10.1093/carcin/bgl100openalex-snapshot
Overexpression of Cdc20 leads to impairment of the spindle assembly checkpoint and aneuploidization in oral cancer
inferredcites →https://doi.org/10.1093/hmg/10.7.699openalex-snapshot
The Rb/E2F pathway and cancer
inferredcites →https://doi.org/10.1093/nar/25.24.4926openalex-snapshot
CDF-1-mediated repression of cell cycle genes targets a specific subset of transactivators [corrected and republished in Nucleic Acids Res 1998 Feb 15;26(4):4926-32]
inferredcites →https://doi.org/10.1093/nar/26.4.0-bopenalex-snapshot
CDF-1 mediated repression of cell cycle genes targets a specific subset of transactivators.
inferredcites →https://doi.org/10.1093/nar/26.5.1135openalex-snapshot
A survey of 178 NF-Y binding CCAAT boxes
inferredcites →https://doi.org/10.1093/nar/28.22.4410openalex-snapshot
The tumour suppressor protein p53 can repress transcription of cyclin B
inferredcites →https://doi.org/10.1093/nar/30.9.1967openalex-snapshot
A single cell cycle genes homology region (CHR) controls cell cycle-dependent transcription of the cdc25C phosphatase gene and is able to cooperate with E2F or Sp1/3 sites
inferredcites →https://doi.org/10.1093/nar/gkp110openalex-snapshot
DNA damage induced p53 downregulates Cdc20 by direct binding to its promoter causing chromatin remodeling
inferredcites →https://doi.org/10.1111/j.1742-4658.2009.07508.xopenalex-snapshot
The central role of CDE/CHR promoter elements in the regulation of cell cycle‐dependent gene transcription
inferredcites →https://doi.org/10.1126/science.282.5393.1497openalex-snapshot
Requirement for p53 and p21 to Sustain G 2 Arrest After DNA Damage
inferredcites →https://doi.org/10.1128/mcb.25.17.7423-7431.2005openalex-snapshot
p53-Dependent Transcriptional Repression of c-myc Is Required for G1 Cell Cycle Arrest
inferredcites →https://doi.org/10.1128/mcb.25.9.3737-3751.2005openalex-snapshot
Direct p53 Transcriptional Repression: In Vivo Analysis of CCAAT-Containing G2/M Promoters
inferredcites →https://doi.org/10.1158/0008-5472.can-07-1887openalex-snapshot
A Cell Proliferation and Chromosomal Instability Signature in Anaplastic Thyroid Carcinoma
inferredcites →https://doi.org/10.1158/0008-5472.can-08-4156openalex-snapshot
B-MYB Is Required for Recovery from the DNA Damage–Induced G2 Checkpoint in p53 Mutant Cells
inferredcites →https://doi.org/10.1186/1471-2407-9-87openalex-snapshot
Overexpression of UbcH10 alternates the cell cycle profile and accelerate the tumor proliferation in colon cancer
inferredcites →https://doi.org/10.4161/cc.22917openalex-snapshot
p53 can repress transcription of cell cycle genes through a p21WAF1/CIP1-dependent switch from MMB to DREAM protein complex binding at CHR promoter elements

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4781335openalex-extracted
The Abl1 Tyrosine Kinase and p53 are Key Players in Doxorubicin-Induced Cardiomyopathy and Their Cell Death Signaling Differs in Atrial and Ventricular Cardiomyocytes
inferred← citeshttps://doi.org/10.1002/1873-3468.14890openalex-snapshot
Disrupting the interaction between a p53 gain‐of‐function mutant and the transcriptional co‐activator PC 4 reverses drug resistance in cancer cells
inferred← citeshttps://doi.org/10.1002/adtp.201900210openalex-snapshot
Significance of Selective Protein Degradation in the Development of Novel Targeted Drugs and Its Implications in Cancer Therapy
inferred← citeshttps://doi.org/10.1002/cam4.1406openalex-snapshot
Functional transcriptomic annotation and protein–protein interaction analysis identify EZH 2 and UBE 2C as key upregulated proteins in ovarian cancer
inferred← citeshttps://doi.org/10.1007/s11033-023-08611-1openalex-snapshot
Molecular and biological factors in the prognosis of head and neck squamous cell cancer
inferred← citeshttps://doi.org/10.1016/j.apsb.2023.07.019openalex-snapshot
Function, mechanism and drug discovery of ubiquitin and ubiquitin-like modification with multiomics profiling for cancer therapy
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2016.12.005openalex-snapshot
NF-Y in cancer: Impact on cell transformation of a gene essential for proliferation
inferred← citeshttps://doi.org/10.1016/j.bbcan.2024.189082openalex-snapshot
Expression and function of NF-Y subunits in cancer
inferred← citeshttps://doi.org/10.1016/j.bbrc.2019.12.058openalex-snapshot
Depletion of UBE2C reduces ovarian cancer malignancy and reverses cisplatin resistance via downregulating CDK1
inferred← citeshttps://doi.org/10.1016/j.bbrc.2026.153550openalex-snapshot
UBE2C-orchestrated ubiquitination networks in cancer progression and therapy resistance
inferred← citeshttps://doi.org/10.1016/j.bbrc.2026.154613openalex-snapshot
Identification of repositioned inhibitors of pan-cancer proteasomal target as potential anti-proliferative candidates using a computational therapeutics approach
inferred← citeshttps://doi.org/10.1016/j.isci.2022.105521openalex-snapshot
Single-cell transcriptomic mapping of intestinal epithelium that undergoes 3D morphogenesis and mechanodynamic stimulation in a gut-on-a-chip
inferred← citeshttps://doi.org/10.1016/j.isci.2024.109995openalex-snapshot
ESR1 and p53 interactome alteration defines mechanisms of tamoxifen response in luminal breast cancer
inferred← citeshttps://doi.org/10.1038/s41420-022-00935-4openalex-snapshot
Ubiquitin conjugating enzyme E2 C (UBE2C) may play a dual role involved in the progression of thyroid carcinoma
inferred← citeshttps://doi.org/10.1039/c8ra10245gopenalex-snapshot
Fabrication of an immunosensor for quantitative detection of breast cancer biomarker UBE2C
inferred← citeshttps://doi.org/10.1042/bsr20182384openalex-snapshot
UBE2C functions as a potential oncogene by enhancing cell proliferation, migration, invasion, and drug resistance in hepatocellular carcinoma cells
inferred← citeshttps://doi.org/10.1080/02648725.2023.2174688openalex-snapshot
Maximal clique centrality and bottleneck genes as novel biomarkers in ovarian cancer
inferred← citeshttps://doi.org/10.1093/carcin/bgaf082openalex-snapshot
SRSF3 knockdown-induced cellular senescence as a possible therapeutic strategy for non-small cell lung cancer
inferred← citeshttps://doi.org/10.1101/2020.03.30.015180openalex-snapshot
Identification of the associated expression patterns as potential predictive markers for cancer prognosis
inferred← citeshttps://doi.org/10.1101/2023.02.17.528954openalex-snapshot
Reversal of drug resistance by disruption of a Gain-of-Function mutant p53 and transcriptional co-activator PC4 interaction
inferred← citeshttps://doi.org/10.1155/2021/9250207openalex-snapshot
Pan-Cancer Analyses of the Tumor Microenvironment Reveal That Ubiquitin-Conjugating Enzyme E2C Might Be a Potential Immunotherapy Target
inferred← citeshttps://doi.org/10.1158/1541-7786.mcr-19-0561openalex-snapshot
UBE2C Is Upregulated by Estrogen and Promotes Epithelial–Mesenchymal Transition via p53 in Endometrial Cancer
inferred← citeshttps://doi.org/10.1186/s12864-016-3436-1openalex-snapshot
Comparison of gene expression response to neutron and x-ray irradiation using mouse blood
inferred← citeshttps://doi.org/10.1186/s12967-024-05623-8openalex-snapshot
The Abl1 tyrosine kinase is a key player in doxorubicin-induced cardiomyopathy and its p53/p73 cell death mediated signaling differs in atrial and ventricular cardiomyocytes
inferred← citeshttps://doi.org/10.1210/endocr/bqag012openalex-snapshot
Single-cell analysis identifies ATC-like cells driving progression in relapsed follicular thyroid carcinoma
inferred← citeshttps://doi.org/10.14264/uql.2017.756openalex-snapshot
DNA methylation and chromatin dynamics during postnatal cardiomyocyte maturation
inferred← citeshttps://doi.org/10.15252/embr.201643347openalex-snapshot
p53 gain‐of‐function mutations increase Cdc7‐dependent replication initiation
inferred← citeshttps://doi.org/10.18632/oncotarget.19608openalex-snapshot
Identification of a p53-repressed gene module in breast cancer cells
inferred← citeshttps://doi.org/10.21203/rs.3.rs-135007/v1openalex-snapshot
Identification of Hub Genes and Pathways With Immune Cell Infiltration in Cholangiocarcinoma by Weighted Gene Co-expression Network Analysis
inferred← citeshttps://doi.org/10.3389/fonc.2020.604124openalex-snapshot
Cancer Stemness: p53 at the Wheel
inferred← citeshttps://doi.org/10.3390/biom10111557openalex-snapshot
More than Meets the ISG15: Emerging Roles in the DNA Damage Response and Beyond
inferred← citeshttps://doi.org/10.3390/diagnostics10090674openalex-snapshot
UBE2C is a Potential Biomarker for Tumorigenesis and Prognosis in Tongue Squamous Cell Carcinoma
inferred← citeshttps://doi.org/10.3390/genes10110852openalex-snapshot
Genome-Wide Small RNA Sequencing Identifies MicroRNAs Deregulated in Non-Small Cell Lung Carcinoma Harboring Gain-of-Function Mutant p53
inferred← citeshttps://doi.org/10.3390/genes9040188openalex-snapshot
UBE2C Is a Transcriptional Target of the Cell Cycle Regulator FOXM1
inferred← citeshttps://doi.org/10.3892/ol.2019.11040openalex-snapshot
Identification of key candidate genes and pathways in endometrial cancer: Evidence from bioinformatics analysis
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.