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Inhibition of Lysyl Oxidase Family of Enzymes Has No Effect on Healthy Fibroblast – Extracellular Matrix Cross-Talk in vitro

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Lysyl oxidase: Properties, specificity, and biological roles inside and outside of the cell

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Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissues

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Roles of Periostin in Asthma

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Characterization of a new tissue-engineered human skin equivalent with hair

inferredcites →https://doi.org/10.1007/s12011-014-0142-1openalex-extracted

The Copper Chelator Tetrathiomolybdate Regressed Bleomycin-Induced Pulmonary Fibrosis in Mice, by Reducing Lysyl Oxidase Expressions

inferredcites →https://doi.org/10.1007/s12307-012-0105-zopenalex-extracted

Lysyl Oxidase, Extracellular Matrix Remodeling and Cancer Metastasis

inferredcites →https://doi.org/10.1016/j.bbadis.2018.01.019openalex-extracted

Inhibition of lysyl oxidase-like 1 (LOXL1) expression arrests liver fibrosis progression in cirrhosis by reducing elastin crosslinking

inferredcites →https://doi.org/10.1016/j.biopha.2018.08.156openalex-extracted

Knockdown of LOXL1 inhibits TGF-β1-induced proliferation and fibrogenesis of hepatic stellate cells by inhibition of Smad2/3 phosphorylation

inferredcites →https://doi.org/10.1016/j.ccr.2005.08.010openalex-extracted

Tensional homeostasis and the malignant phenotype

inferredcites →https://doi.org/10.1016/j.cell.2009.10.027openalex-extracted

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

inferredcites →https://doi.org/10.1016/j.csbj.2018.07.003openalex-extracted

Biophysics of Tumor Microenvironment and Cancer Metastasis - A Mini Review

inferredcites →https://doi.org/10.1016/j.jtemb.2017.08.011openalex-extracted

The copper dependent-lysyl oxidases contribute to the pathogenesis of pulmonary emphysema in chronic obstructive pulmonary disease patients

inferredcites →https://doi.org/10.1016/s0923-1811(97)00607-5openalex-extracted

Regulations of collagen synthesis by ascorbic acid, transforming growth factor-β and interferon-γ in human dermal fibroblasts cultured in three-dimensional collagen gel are photoaging- and aging-independent

inferredcites →https://doi.org/10.1016/s1535-6108(04)00375-7openalex-extracted

Context, tissue plasticity, and cancerAre tumor stem cells also regulated by the microenvironment?

inferredcites →https://doi.org/10.1016/s2213-2600(16)30421-0openalex-extracted

Efficacy of simtuzumab versus placebo in patients with idiopathic pulmonary fibrosis: a randomised, double-blind, controlled, phase 2 trial

inferredcites →https://doi.org/10.1038/nm.2208openalex-extracted

Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment

inferredcites →https://doi.org/10.1038/nmeth.2019openalex-extracted

Fiji: an open-source platform for biological-image analysis

inferredcites →https://doi.org/10.1038/nrc2544openalex-extracted

A tense situation: forcing tumour progression

inferredcites →https://doi.org/10.1038/onc.2014.52openalex-extracted

Extracellular calumenin suppresses ERK1/2 signaling and cell migration by protecting fibulin-1 from MMP-13-mediated proteolysis

inferredcites →https://doi.org/10.1038/s41598-022-09557-3openalex-extracted

BMP1 is not required for lung fibrosis in mice

inferredcites →https://doi.org/10.1039/c6tb00807kopenalex-extracted

Collagen: a network for regenerative medicine

inferredcites →https://doi.org/10.1073/pnas.1004952107openalex-extracted

LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling

inferredcites →https://doi.org/10.1074/jbc.m109.088864openalex-extracted

Interaction between Periostin and BMP-1 Promotes Proteolytic Activation of Lysyl Oxidase

inferredcites →https://doi.org/10.1074/jbc.ra119.007806openalex-extracted

Differential cleavage of lysyl oxidase by the metalloproteinases BMP1 and ADAMTS2/14 regulates collagen binding through a tyrosine sulfate domain

inferredcites →https://doi.org/10.1091/mbc.e19-03-0140openalex-extracted

Fibronectin matrix as a scaffold for procollagen proteinase binding and collagen processing

inferredcites →https://doi.org/10.1093/ajcn/67.5.996sopenalex-extracted

Copper, lysyl oxidase, and extracellular matrix protein cross-linking

inferredcites →https://doi.org/10.1093/cvr/cvv214openalex-extracted

Matrix cross-linking lysyl oxidases are induced in response to myocardial infarction and promote cardiac dysfunction

inferredcites →https://doi.org/10.1096/fj.202101553ropenalex-extracted

Differential roles for lysyl oxidase (like), family members in chronic obstructive pulmonary disease; from gene and protein expression to function

inferredcites →https://doi.org/10.1101/cshperspect.a005058openalex-extracted

Extracellular Matrix Degradation and Remodeling in Development and Disease

inferredcites →https://doi.org/10.1111/1523-1747.ep12543573openalex-extracted

Collagen Synthesis in Cultured Human Skin Fibroblasts: Effect of Ascorbic Acid and Its Analogs

inferredcites →https://doi.org/10.1111/febs.15776openalex-extracted

A guide to the composition and functions of the extracellular matrix

inferredcites →https://doi.org/10.1111/jcmm.14074openalex-extracted

The lysyl oxidase like 2/3 enzymatic inhibitor, PXS‐5153A, reduces crosslinks and ameliorates fibrosis

inferredcites →https://doi.org/10.1152/ajpcell.00012.2020openalex-extracted

Extracellular BMP1 is the major proteinase for COOH-terminal proteolysis of type I procollagen in lung fibroblasts

inferredcites →https://doi.org/10.1152/ajplung.00067.2019openalex-extracted

Moderate hyperoxia induces senescence in developing human lung fibroblasts

inferredcites →https://doi.org/10.1158/0008-5472.can-12-2233openalex-extracted

LOX-Mediated Collagen Crosslinking Is Responsible for Fibrosis-Enhanced Metastasis

inferredcites →https://doi.org/10.1165/rcmb.2016-0379ocopenalex-extracted

Extracellular Matrix Cross-Linking Enhances Fibroblast Growth and Protects against Matrix Proteolysis in Lung Fibrosis

inferredcites →https://doi.org/10.1172/jci.insight.86380openalex-extracted

Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases

inferredcites →https://doi.org/10.1183/13993003.04361-2020openalex-extracted

Lysyl oxidase like 2 is increased in asthma and contributes to asthmatic airway remodelling

inferredcites →https://doi.org/10.1186/s12931-020-1299-0openalex-extracted

Periostin plays a critical role in the cell cycle in lung fibroblasts

inferredcites →https://doi.org/10.1242/dmm.030114openalex-extracted

Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis

inferredcites →https://doi.org/10.1371/journal.pone.0013360openalex-extracted

Fibulin-1 Is Increased in Asthma – A Novel Mediator of Airway Remodeling?

inferredcites →https://doi.org/10.1378/chest.13-2688openalex-extracted

Fibulin-1 Predicts Disease Progression in Patients With Idiopathic Pulmonary Fibrosis

inferredcites →https://doi.org/10.1513/annalsats.201406-240mgopenalex-extracted

Lung Extracellular Matrix and Fibroblast Function

inferredcites →https://doi.org/10.3390/ijms18010062openalex-extracted

Lysyl Oxidase and the Tumor Microenvironment

inferredcites →https://doi.org/10.3390/ijms23063285openalex-extracted

Cleavage of LOXL1 by BMP1 and ADAMTS14 Proteases Suggests a Role for Proteolytic Processing in the Regulation of LOXL1 Function

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