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A Pharmacological Toolkit for Human Microglia Identifies Topoisomerase I Inhibitors as Immunomodulators for Alzheimer's Disease
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Differential induction of chemokines in human microglia by type i and ii interferons
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Camptothecin and Topotecan, Inhibitors of Transcription Factor Fli‐1 and Topoisomerase, Markedly Ameliorate Lupus Nephritis in (NZB × NZW)F1 Mice and Reduce the Production of Inflammatory Mediators in Human Renal Cells
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Efficient Derivation of Excitatory and Inhibitory Neurons from Human Pluripotent Stem Cells Stably Expressing Direct Reprogramming Factors
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Comprehensive Integration of Single-Cell Data
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Microglia Biology: One Century of Evolving Concepts
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Single-Cell Transcriptomics Analyses of Neural Stem Cell Heterogeneity and Contextual Plasticity in a Zebrafish Brain Model of Amyloid Toxicity
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DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors
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Benchmarking Computational Doublet-Detection Methods for Single-Cell RNA Sequencing Data
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Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming
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Topotecan Alleviates Lipopolysaccharide-Mediated Acute Lung Injury Via the NF-κB Signaling Pathway
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iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases
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Narciclasine inhibits LPS-induced neuroinflammation by modulating the Akt/IKK/NF-κB and JNK signaling pathways
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Modulation of mitochondrial bioenergetics in a skeletal muscle cell line model of mitochondrial toxicity
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Chemical Approaches to Stem Cell Biology and Therapeutics
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clusterProfiler 4.0: A universal enrichment tool for interpreting omics data
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Discovery of Potent Cholinesterase Inhibition-Based Multi-Target-Directed Lead Compounds for Synaptoprotection in Alzheimer’s Disease
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FDA approves second anti-amyloid antibody for Alzheimer disease
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Landmark Alzheimer’s drug approval confounds research community
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High-throughput Microwell-seq 2.0 profiles massively multiplexed chemical perturbation
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Neuropathological correlates and genetic architecture of microglial activation in elderly human brain
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APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids
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Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease
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Species-specific metabolic reprogramming in human and mouse microglia during inflammatory pathway induction
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Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution
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Quantifying the effect of experimental perturbations at single-cell resolution
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A Python library for probabilistic analysis of single-cell omics data
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Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro
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Benchmarking atlas-level data integration in single-cell genomics
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Microglia ferroptosis is regulated by SEC24B and contributes to neurodegeneration
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Microglial morphology in Alzheimer’s disease and after Aβ immunotherapy
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Multifaceted mitochondria: moving mitochondrial science beyond function and dysfunction
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Assessing mitochondrial dysfunction in cells
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Chemical compound-based direct reprogramming for future clinical applications
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Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
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Statistical significance for genomewide studies
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demuxmix: demultiplexing oligonucleotide-barcoded single-cell RNA sequencing data with regression mixture models
inferredcites →https://doi.org/10.1093/bioinformatics/bts356openalex-extracted
RSeQC: quality control of RNA-seq experiments
inferredcites →https://doi.org/10.1093/bioinformatics/bts635openalex-extracted
STAR: ultrafast universal RNA-seq aligner
inferredcites →https://doi.org/10.1093/bioinformatics/btt656openalex-extracted
featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
inferredcites →https://doi.org/10.1093/bioinformatics/bty648openalex-extracted
Scaling read aligners to hundreds of threads on general-purpose processors
inferredcites →https://doi.org/10.1093/nar/gkaa1011openalex-extracted
MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations
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A cross-disease human microglial framework identifies disease-enriched subsets and tool compounds for microglial polarization
inferredcites →https://doi.org/10.1101/2023.06.03.543569openalex-extracted
Early Alzheimer’s disease pathology in human cortex is associated with a transient phase of distinct cell states
inferredcites →https://doi.org/10.1111/acel.13606openalex-extracted
Transcriptional landscape of human microglia implicates age, sex, and APOE‐related immunometabolic pathway perturbations
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Alzheimer's Disease Is a Synaptic Failure
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Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
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Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation
inferredcites →https://doi.org/10.1126/science.aba5906openalex-extracted
Human fetal microglia acquire homeostatic immune-sensing properties early in development
inferredcites →https://doi.org/10.1136/ejhpharm-2019-002026openalex-extracted
Cladribine repurposed in multiple sclerosis: making a fortune out of a generic drug
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Microglia Function in the Central Nervous System During Health and Neurodegeneration
inferredcites →https://doi.org/10.1182/blood-2010-10-314120openalex-extracted
mpeg1 promoter transgenes direct macrophage-lineage expression in zebrafish
inferredcites →https://doi.org/10.1186/cc11767openalex-extracted
Toll-like receptor 4 in phagocytosis of Escherichia coli by endotoxin-activated human neutrophils in whole blood
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Selecting single cell clustering parameter values using subsampling-based robustness metrics
inferredcites →https://doi.org/10.1186/s13024-018-0297-xopenalex-extracted
Development and validation of a simplified method to generate human microglia from pluripotent stem cells
inferredcites →https://doi.org/10.1186/s13059-014-0550-8openalex-extracted
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
inferredcites →https://doi.org/10.1186/s13059-015-0844-5openalex-extracted
MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data
inferredcites →https://doi.org/10.1371/journal.pone.0152016openalex-extracted
Determining Maximum Glycolytic Capacity Using Extracellular Flux Measurements
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Microglial mTOR Activation Upregulates Trem2 and Enhances β-Amyloid Plaque Clearance in the 5XFAD Alzheimer's Disease Model
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Microglial subtypes: diversity within the microglial community
inferredcites →https://doi.org/10.15252/embr.202154499openalex-extracted
Myeloid cell‐specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation
inferredcites →https://doi.org/10.3389/fimmu.2020.00493openalex-extracted
Metabolic Reprograming of Microglia in the Regulation of the Innate Inflammatory Response
inferredcites →https://doi.org/10.3389/fnmol.2020.00134openalex-extracted
Profiling Microglia From Alzheimer’s Disease Donors and Non-demented Elderly in Acute Human Postmortem Cortical Tissue
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Phagocytic Glial Cells in Brain Homeostasis
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Microglia-like Cells Promote Neuronal Functions in Cerebral Organoids
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Single Cell/Nucleus Transcriptomics Comparison in Zebrafish and Humans Reveals Common and Distinct Molecular Responses to Alzheimer’s Disease
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Enzymatic Dissociation Induces Transcriptional and Proteotype Bias in Brain Cell Populations
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Microglial CD74 Expression Is Regulated by TGFβ Signaling
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Convection Enhanced Delivery of Topotecan for Gliomas: A Single-Center Experience
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CD74: a prospective marker for reactive microglia?
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Scikit-learn: Machine Learning in Python
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Mitochondrial phenotypes in purified human immune cell subtypes and cell mixtures
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