On the public citation graph
ANGPTL8 (betatrophin) role in diabetes and metabolic diseases
Inferred edges come from two machine sources: sweeps of open repository
metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is
labelled with the one it came from. Neither is a complete citation index — absence here is not
evidence of absence.
1 of the 63 references listed on this page is in the Retraction Watch database as retracted (export 2026-11-04): 10.1016/j.cell.2013.04.008 (notice 2017-01-01).
Dataset join, best-effort; this page does not check the publisher record.
Retraction Watch data via Crossref Labs, used with credit; OpenCitations Index (CC0) and Meta (CC BY 4.0);
dataset doi:10.7910/DVN/WT8VOA (CC BY 4.0).
Is this your work? Sign in with ORCID and put your name on the
claims that are yours.
Reference health. See whether every reference in this work resolves to a
known work and none has been retracted — and get a dated
CiteStamped
badge you can embed.
What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/oby.21038openalex-snapshotSerum betatrophin concentrations are significantly increased in overweight but not in obese or type 2 diabetic individuals
inferredcites →https://doi.org/10.1007/s00125-014-3208-xopenalex-snapshotCirculating betatrophin correlates with atherogenic lipid profiles but not with glucose and insulin levels in insulin-resistant individuals
inferredcites →https://doi.org/10.1038/ijo.2015.206openalex-snapshotInterplay of atherogenic factors, protein intake and betatrophin levels in obese–metabolic syndrome patients treated with hypocaloric diets
inferredcites →https://doi.org/10.1038/srep10949openalex-snapshotHigher plasma betatrophin/ANGPTL8 level in Type 2 Diabetes subjects does not correlate with blood glucose or insulin resistance
inferredcites →https://doi.org/10.1038/srep18502openalex-snapshotA lipasin/Angptl8 monoclonal antibody lowers mouse serum triglycerides involving increased postprandial activity of the cardiac lipoprotein lipase
inferredcites →https://doi.org/10.1155/2016/2616539openalex-snapshotCirculating Levels of Betatrophin and Irisin Are Not Associated with Pancreaticβ-Cell Function in Previously Diagnosed Type 2 Diabetes Mellitus Patients
inferredcites →https://doi.org/10.1210/jc.2014-2300openalex-snapshotCirculating Betatrophin Levels Are Increased in Patients With Type 2 Diabetes and Associated With Insulin Resistance
inferredcites →https://doi.org/10.1530/eje-14-0815openalex-snapshotBetatrophin levels are increased in women with gestational diabetes mellitus compared to healthy pregnant controls
inferredcites →https://doi.org/10.2337/db13-1106openalex-snapshotIrisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling
inferredcites →https://doi.org/10.2337/db13-1435openalex-snapshotElevated Mouse Hepatic Betatrophin Expression Does Not Increase Human β-Cell Replication in the Transplant Setting
inferredcites →https://doi.org/10.2337/db14-0009openalex-snapshotBetatrophin Versus Bitter-Trophin and the Elephant in the Room: Time for a New Normal in β-Cell Regeneration Research
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4795161openalex-extractedAdipose Angptl8 Controls Glucose and Energy Metabolism and its Suppression in Mice Improves Diet Induced Obesity and Inflammation
inferred← citeshttps://doi.org/10.1002/dmrr.3612openalex-snapshotMaternal and cord blood betatrophin (angiopoietin‐like protein 8) in pregnant women with gestational diabetes and normoglycemic controls: A systematic review, meta‐analysis, and meta‐regression
inferred← citeshttps://doi.org/10.1002/dmrr.3643openalex-snapshotPlasma insulin is required for the increase in plasma angiopoietin‐like protein 8 in response to nutrient ingestion
inferred← citeshttps://doi.org/10.1002/hep.30030openalex-snapshotHepatocellular Carcinoma‐Associated Protein TD26 Interacts and Enhances Sterol Regulatory Element‐Binding Protein 1 Activity to Promote Tumor Cell Proliferation and Growth
inferred← citeshttps://doi.org/10.1007/s00289-018-2549-xopenalex-snapshotSEMI-empirical PM6 method applied in the analysis of thermodynamics properties and molecular orbitals at different temperatures of adsorption drugs on chitosan hydrogels for type 2 diabetes
inferred← citeshttps://doi.org/10.1016/j.cca.2024.117775openalex-snapshotThe association between plasma angiopoietin-like protein 4, glucose and lipid metabolism during pregnancy, placental function, and risk of delivering large-for-gestational-age neonates
inferred← citeshttps://doi.org/10.1016/j.numecd.2022.04.006openalex-snapshotEffect of physical activity in a weight loss program on circulating total ANGPTL8 concentrations in northern Americans with obesity: A prospective randomized controlled trial
inferred← citeshttps://doi.org/10.1038/s41598-020-63076-7openalex-snapshotCorrelation of circulating ANGPTL5 levels with obesity, high sensitivity C-reactive protein and oxidized low-density lipoprotein in adolescents
inferred← citeshttps://doi.org/10.1038/s41598-020-69091-yopenalex-snapshotThe circulating ANGPTL8 levels show differences among novel subgroups of adult patients with diabetes and are associated with mortality in the subsequent 5 years
inferred← citeshttps://doi.org/10.1111/jcmm.14488openalex-snapshotAngiopoietin‐like protein 8 expression and association with extracellular matrix metabolism and inflammation during intervertebral disc degeneration
inferred← citeshttps://doi.org/10.1155/2020/1621239openalex-snapshotThe ANGPTL8 rs2278426 (C/T) Polymorphism Is Associated with Prediabetes and Type 2 Diabetes in a Han Chinese Population in Hebei Province
inferred← citeshttps://doi.org/10.1155/2022/1113811openalex-snapshotAngiopoietin-Like 8 in Gestational Diabetes Mellitus: Reduced Levels in Third Trimester Maternal Serum and Placenta, Increased Levels in Cord Blood Serum
inferred← citeshttps://doi.org/10.1177/14791641241259792openalex-snapshotThe correlations between angiopoietin like 8 and cardiometabolic risk factors in Saudi women with type 2 diabetes mellitus: A pilot study
inferred← citeshttps://doi.org/10.1186/s12887-025-05833-zopenalex-snapshotCirculating fibroblast growth factor-21, Omentin-1, and betatrophin and their association with metabolic parameters in Saudi adolescents post 12-month lifestyle change program
inferred← citeshttps://doi.org/10.1186/s12933-018-0687-yopenalex-snapshotTriglyceride-mediated influence of serum angiopoietin-like protein 8 on subclinical atherosclerosis in type 2 diabetic patients: results from the GDMD study in China
inferred← citeshttps://doi.org/10.1507/endocrj.ej18-0191openalex-snapshotEffects of a diet with or without physical activity on angiopoietin-like protein 8 concentrations in overweight/obese patients with newly diagnosed type 2 diabetes: a randomized controlled trial
inferred← citeshttps://doi.org/10.1515/jbcpp-2021-0393openalex-snapshotModerate-intensity exercise decreases the circulating level of betatrophin and its correlation among markers of obesity in women
inferred← citeshttps://doi.org/10.2147/dmso.s330700openalex-snapshotANGPTL8/Betatrophin Improves Glucose Tolerance in Older Mice and Metabolomic Analysis Reveals Its Role in Insulin Resistance in HepG2 Cells
inferred← citeshttps://doi.org/10.29333/ejgm/18521openalex-snapshotSerum betatrophin and irisin levels in patients with polycystic ovary syndrome with and without insulin resistance
inferred← citeshttps://doi.org/10.3389/fendo.2018.00414openalex-snapshotAssociation of Serum Angiopoietin-Like Protein 8 With Albuminuria in Type 2 Diabetic Patients: Results From the GDMD Study in China
inferred← citeshttps://doi.org/10.3390/cells12212563openalex-snapshotThe Proinflammatory Role of ANGPTL8 R59W Variant in Modulating Inflammation through NF-κB Signaling Pathway under TNFα Stimulation
inferred← citeshttps://doi.org/10.3390/ijms20174223openalex-snapshotLoss of Glycine N-Methyltransferase Associates with Angiopoietin-Like Protein 8 Expression in High Fat-Diet-Fed Mice
inferred← citeshttps://doi.org/10.3390/jcm14145006openalex-snapshotImpact of Tumor Necrosis Factor Antagonist Therapy on Circulating Angiopoietin-like Protein 8 (ANGPTL8) Levels in Crohn’s Disease—A Prospective Multi-Center Study
inferred← citeshttps://doi.org/10.3892/mmr.2019.10719openalex-snapshotRecombinant betatrophin (Angptl‑8/lipasin) ameliorates streptozotocin‑induced hyperglycemia and β‑cell destruction in neonatal rats
Editorial review for independent work. ICSAC — the Institute for Complexity
Science and Advanced Computing — runs a structured editorial panel for researchers
publishing outside journals, and publishes on CiteStamp rails. Submission is free
and goes through ORCID:
icsacinstitute.org/submit.