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Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1001/archinte.160.7.898openalex-snapshot
Overweight, Obesity, and Health Risk
inferredcites →https://doi.org/10.1007/s00125-005-1818-zopenalex-snapshot
Insulin resistance and the metabolic syndrome
inferredcites →https://doi.org/10.1016/j.bbalip.2011.10.010openalex-snapshot
Regulation of triglyceride metabolism by Angiopoietin-like proteins
inferredcites →https://doi.org/10.1016/j.cmet.2011.11.007openalex-snapshot
Identifying Novel Transcriptional Components Controlling Energy Metabolism
inferredcites →https://doi.org/10.1016/s0002-9149(99)00211-8openalex-snapshot
Hypertriglyceridemia, insulin resistance, and the metabolic syndrome
inferredcites →https://doi.org/10.1038/nature09270openalex-snapshot
Biological, clinical and population relevance of 95 loci for blood lipids
inferredcites →https://doi.org/10.1038/nbt.1644openalex-snapshot
A mouse knockout library for secreted and transmembrane proteins
inferredcites →https://doi.org/10.1038/ng.291openalex-snapshot
Common variants at 30 loci contribute to polygenic dyslipidemia
inferredcites →https://doi.org/10.1038/ng.76openalex-snapshot
Newly identified loci that influence lipid concentrations and risk of coronary artery disease
inferredcites →https://doi.org/10.1038/ng1984openalex-snapshot
Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL
inferredcites →https://doi.org/10.1038/ng814openalex-snapshot
Angptl3 regulates lipid metabolism in mice
inferredcites →https://doi.org/10.1056/nejmoa0808949openalex-snapshot
Functional Brown Adipose Tissue in Healthy Adults
inferredcites →https://doi.org/10.1056/nejmoa0810780openalex-snapshot
Identification and Importance of Brown Adipose Tissue in Adult Humans
inferredcites →https://doi.org/10.1056/nejmoa1002926openalex-snapshot
Exome Sequencing, ANGPTL3 Mutations, and Familial Combined Hypolipidemia
inferredcites →https://doi.org/10.1073/pnas.0705041104openalex-snapshot
Lipid-lowering effects of anti-angiopoietin-like 4 antibody recapitulate the lipid phenotype found in angiopoietin-like 4 knockout mice
inferredcites →https://doi.org/10.1074/jbc.m302861200openalex-snapshot
Protein Region Important for Regulation of Lipid Metabolism in Angiopoietin-like 3 (ANGPTL3)
inferredcites →https://doi.org/10.1074/jbc.m506519200openalex-snapshot
The Fasting-induced Adipose Factor/Angiopoietin-like Protein 4 Is Physically Associated with Lipoproteins and Governs Plasma Lipid Levels and Adiposity
inferredcites →https://doi.org/10.1074/jbc.m807899200openalex-snapshot
Identification of a New Functional Domain in Angiopoietin-like 3 (ANGPTL3) and Angiopoietin-like 4 (ANGPTL4) Involved in Binding and Inhibition of Lipoprotein Lipase (LPL)
inferredcites →https://doi.org/10.1093/bioinformatics/btm404openalex-snapshot
Clustal W and Clustal X version 2.0
inferredcites →https://doi.org/10.1093/nar/25.17.3389openalex-snapshot
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
inferredcites →https://doi.org/10.1097/mol.0b013e328333269eopenalex-snapshot
Impacts of angiopoietin-like proteins on lipoprotein metabolism and cardiovascular events
inferredcites →https://doi.org/10.1111/j.1753-4887.1998.tb01722.xopenalex-snapshot
The Obesity Epidemic Is a Worldwide Phenomenon
inferredcites →https://doi.org/10.1126/science.280.5368.1367openalex-snapshot
As Obesity Rates Rise, Experts Struggle to Explain Why
inferredcites →https://doi.org/10.1152/ajpendo.00717.2006openalex-snapshot
A high-fat, ketogenic diet induces a unique metabolic state in mice
inferredcites →https://doi.org/10.1161/01.atv.0000252827.51626.89openalex-snapshot
Angiopoietin-Like Protein3 Regulates Plasma HDL Cholesterol Through Suppression of Endothelial Lipase
inferredcites →https://doi.org/10.1161/circulationaha.105.169404openalex-snapshot
Diagnosis and Management of the Metabolic Syndrome
inferredcites →https://doi.org/10.1172/jci19451openalex-snapshot
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
inferredcites →https://doi.org/10.1172/jci37118openalex-snapshot
Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans
inferredcites →https://doi.org/10.1210/en.2005-0476openalex-snapshot
Transgenic Angiopoietin-Like (Angptl)4 Overexpression and Targeted Disruption of Angptl4 and Angptl3: Regulation of Triglyceride Metabolism
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4795161openalex-extracted
Adipose Angptl8 Controls Glucose and Energy Metabolism and its Suppression in Mice Improves Diet Induced Obesity and Inflammation
inferred← citeshttps://doi.org/10.1002/adbi.202200093openalex-snapshot
The Regulation of Triacylglycerol Metabolism and Lipoprotein Lipase Activity
inferred← citeshttps://doi.org/10.1002/advs.202509351openalex-snapshot
Nonalcoholic Fatty Liver Disease Exacerbates the Advancement of Renal Fibrosis by Modulating Renal CCR2 + PIRB + Macrophages Through the ANGPTL8/PIRB/ALOX5AP Axis
inferred← citeshttps://doi.org/10.1002/cph4.70248openalex-snapshot
Exercise‐Regulated Irisin Signaling in Glucose Homeostasis and Diabetes: The Myogenic Benefits for Metabolic Health
inferred← citeshttps://doi.org/10.1002/dmrr.2919openalex-snapshot
ANGPTL8 (betatrophin) role in diabetes and metabolic diseases
inferred← citeshttps://doi.org/10.1002/dmrr.3612openalex-snapshot
Maternal and cord blood betatrophin (angiopoietin‐like protein 8) in pregnant women with gestational diabetes and normoglycemic controls: A systematic review, meta‐analysis, and meta‐regression
inferred← citeshttps://doi.org/10.1002/jcb.30252openalex-snapshot
Contribution of organokines in the development of NAFLD/NASH associated hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1002/jcla.22649openalex-snapshot
Association between rs2278426 (C/T) and rs892066 (C/G) variants of ANGPTL8 (betatrophin) and susceptibility to type2 diabetes mellitus
inferred← citeshttps://doi.org/10.1002/jcp.30534openalex-snapshot
Emerging roles of angiopoietin‐like proteins in inflammation: Mechanisms and potential as pharmacological targets
inferred← citeshttps://doi.org/10.1002/oby.21038openalex-snapshot
Serum betatrophin concentrations are significantly increased in overweight but not in obese or type 2 diabetic individuals
inferred← citeshttps://doi.org/10.1007/164_2015_6openalex-snapshot
Adipokines and the Endocrine Role of Adipose Tissues
inferred← citeshttps://doi.org/10.1007/164_2021_520openalex-snapshot
Metabolism of Triglyceride-Rich Lipoproteins
inferred← citeshttps://doi.org/10.1007/978-3-030-81303-1_19-1openalex-snapshot
Serum Betatrophin: What It Shows and How It Alters in Gestational Diabetes Mellitus
inferred← citeshttps://doi.org/10.1007/978-3-031-08014-2_19openalex-snapshot
Serum Betatrophin: What It Shows and How It Alters in Gestational Diabetes Mellitus
inferred← citeshttps://doi.org/10.1007/978-3-031-58843-3_8openalex-snapshot
Macromolecular Interactions of Lipoprotein Lipase (LPL)
inferred← citeshttps://doi.org/10.1007/s00125-013-3071-1openalex-snapshot
Increased circulating levels of betatrophin in individuals with long-standing type 1 diabetes
inferred← citeshttps://doi.org/10.1007/s00125-014-3208-xopenalex-snapshot
Circulating betatrophin correlates with atherogenic lipid profiles but not with glucose and insulin levels in insulin-resistant individuals
inferred← citeshttps://doi.org/10.1007/s00125-014-3346-1openalex-snapshot
An explanation for recent discrepancies in levels of human circulating betatrophin
inferred← citeshttps://doi.org/10.1007/s00125-015-3521-zopenalex-snapshot
In vivo targeted delivery of ANGPTL8 gene for beta cell regeneration in rats
inferred← citeshttps://doi.org/10.1007/s00125-015-3590-zopenalex-snapshot
Angiopoietin-like protein 8 (ANGPTL8)/betatrophin overexpression does not increase beta cell proliferation in mice
inferred← citeshttps://doi.org/10.1007/s00125-017-4505-yopenalex-snapshot
Angiopoietin-like protein 8 in early pregnancy improves the prediction of gestational diabetes
inferred← citeshttps://doi.org/10.1007/s00125-018-4579-1openalex-snapshot
Angptl8 antisense oligonucleotide improves adipose lipid metabolism and prevents diet-induced NAFLD and hepatic insulin resistance in rodents
inferred← citeshttps://doi.org/10.1007/s00125-018-4604-4openalex-snapshot
Can targeting ANGPTL proteins improve glucose tolerance?
inferred← citeshttps://doi.org/10.1007/s00417-017-3676-zopenalex-snapshot
Expression of angiopoietin-like protein 8 correlates with VEGF in patients with proliferative diabetic retinopathy
inferred← citeshttps://doi.org/10.1007/s10930-019-09825-8openalex-snapshot
Bacteria-Derived Recombinant Human ANGPTL8/Betatrophin Significantly Increases the Level of Triglyceride
inferred← citeshttps://doi.org/10.1007/s11010-020-03725-7openalex-snapshot
Higher circulating levels of ANGPTL8 are associated with body mass index, triglycerides, and endothelial dysfunction in patients with coronary artery disease
inferred← citeshttps://doi.org/10.1007/s11033-021-06270-8openalex-snapshot
ANGPTL8 roles in proliferation, metabolic diseases, hypothyroidism, polycystic ovary syndrome, and signaling pathways
inferred← citeshttps://doi.org/10.1007/s11033-021-06335-8openalex-snapshot
New insights into ANGPTL8 in modulating the development of cardio-metabolic disorder diseases
inferred← citeshttps://doi.org/10.1007/s11332-026-01756-zopenalex-snapshot
Probiotics and exercise modulate hepatic asprosin, betatrophin, Leap-2, and ORM2 gene expression in a high fat diet rat model
inferred← citeshttps://doi.org/10.1007/s11690-015-0492-7openalex-snapshot
Stéatose et résistance à l’insuline : implication des hépatokines
inferred← citeshttps://doi.org/10.1007/s11695-015-2026-7openalex-snapshot
Circulating ANGPTL8/Betatrophin Concentrations Are Increased After Surgically Induced Weight Loss, but Not After Diet-Induced Weight Loss
inferred← citeshttps://doi.org/10.1007/s11756-021-00824-8openalex-snapshot
Molecular cloning and characterization of angiopoietin-like protein-8 gene in pigs and its tissue-specific expression in different animals
inferred← citeshttps://doi.org/10.1007/s11883-023-01179-yopenalex-snapshot
Inhibition of Angiopoietin-Like Protein 3 or 3/8 Complex and ApoC-III in Severe Hypertriglyceridemia
inferred← citeshttps://doi.org/10.1007/s11892-015-0676-4openalex-snapshot
Betatrophin in Diabetes Mellitus: the Epidemiological Evidence in Humans
inferred← citeshttps://doi.org/10.1007/s12020-016-0875-zopenalex-snapshot
Elevated circulating levels of betatrophin are associated with polycystic ovary syndrome
inferred← citeshttps://doi.org/10.1007/s12020-024-03909-xopenalex-snapshot
Dyslipidemia and ANGPTL8 evaluation in young females with Type 1 diabetes mellitus
inferred← citeshttps://doi.org/10.1007/s12265-021-10169-xopenalex-snapshot
Potential of Phage Display Antibody Technology for Cardiovascular Disease Immunotherapy
inferred← citeshttps://doi.org/10.1007/s13167-019-00180-3openalex-snapshot
The potential role of angiopoietin-like protein-8 in type 2 diabetes mellitus: a possibility for predictive diagnosis and targeted preventive measures?
inferred← citeshttps://doi.org/10.1007/s40618-020-01444-wopenalex-snapshot
Angiopoietin-like 8 (ANGPTL8) as a potential predictor of NAFLD in paediatric patients with Prader-Willi Syndrome
inferred← citeshttps://doi.org/10.1007/s42000-019-00095-8openalex-snapshot
Decreased circulating levels of ANGPTL8 in Graves’ disease patients
inferred← citeshttps://doi.org/10.1007/s42000-023-00487-xopenalex-snapshot
Hepatokines: the missing link in the development of insulin resistance and hyperandrogenism in PCOS?
inferred← citeshttps://doi.org/10.1016/b978-0-12-819460-7.00125-0openalex-snapshot
Enzymes | Lipoprotein Lipase
inferred← citeshttps://doi.org/10.1016/j.amjms.2021.05.023openalex-snapshot
Associations Between Betatrophin with Irisin and Metabolic Factors: Effects of Two Exercise Trainings in Diabetic Rats
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2019.11.011openalex-snapshot
High betatrophin in coronary patients protects from cardiovascular events
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2020.06.014openalex-snapshot
Angiopoietin-like protein 8 accelerates atherosclerosis in ApoE−/− mice
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2025.119146openalex-snapshot
The vicious circle of chronic kidney disease and hypertriglyceridemia: What is first, the hen or the egg?
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2025.119235openalex-snapshot
Angiopoietin-like protein inhibitors: Promising agents for the treatment of familial hypercholesterolemia and atherogenic dyslipidemia
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2025.120556openalex-snapshot
The role of ANGPTL8 in metabolism and cardiovascular diseases: Consensus and controversy
inferred← citeshttps://doi.org/10.1016/j.bbalip.2014.03.013openalex-snapshot
Physiological regulation of lipoprotein lipase
inferred← citeshttps://doi.org/10.1016/j.bbalip.2015.11.003openalex-snapshot
Angiopoietin-like protein 8 (betatrophin) is a stress-response protein that down-regulates expression of adipocyte triglyceride lipase
inferred← citeshttps://doi.org/10.1016/j.bbalip.2024.159461openalex-snapshot
Silencing ANGPTL8 reduces mouse preadipocyte differentiation and insulin signaling
inferred← citeshttps://doi.org/10.1016/j.bbrc.2012.12.025openalex-snapshot
Lipasin, thermoregulated in brown fat, is a novel but atypical member of the angiopoietin-like protein family
inferred← citeshttps://doi.org/10.1016/j.bbrc.2013.01.129openalex-snapshot
Emerging roles of Lipasin as a critical lipid regulator
inferred← citeshttps://doi.org/10.1016/j.bbrc.2020.11.053openalex-snapshot
Angiopoietin-like protein 4(E40K) and ANGPTL4/8 complex have reduced, temperature-dependent LPL-inhibitory activity compared to ANGPTL4
inferred← citeshttps://doi.org/10.1016/j.bbrc.2026.154057openalex-snapshot
NRAC: an emerging nutrient-responsive regulator of tissue-specific fatty acid metabolism
inferred← citeshttps://doi.org/10.1016/j.bcp.2021.114502openalex-snapshot
Angiopoietin-like proteins 8 knockout reduces intermittent hypoxia-induced vascular remodeling in a murine model of obstructive sleep apnea
inferred← citeshttps://doi.org/10.1016/j.cca.2019.12.029openalex-snapshot
Triglyceride metabolism and angiopoietin-like proteins in lipoprotein lipase regulation
inferred← citeshttps://doi.org/10.1016/j.cca.2021.05.017openalex-snapshot
ANGPTL8 in cardio-metabolic diseases
inferred← citeshttps://doi.org/10.1016/j.cell.2013.04.008openalex-snapshot
RETRACTED: Betatrophin: A Hormone that Controls Pancreatic β Cell Proliferation
inferred← citeshttps://doi.org/10.1016/j.cell.2014.09.028openalex-snapshot
Perspectives on the Activities of ANGPTL8/Betatrophin
inferred← citeshttps://doi.org/10.1016/j.cjca.2023.06.002openalex-snapshot
Angiopoietin-Like Proteins: Cardiovascular Biology and Therapeutic Targeting for the Prevention of Cardiovascular Diseases
inferred← citeshttps://doi.org/10.1016/j.compbiolchem.2016.01.009openalex-snapshot
Structural characterization of ANGPTL8 (betatrophin) with its interacting partner lipoprotein lipase
inferred← citeshttps://doi.org/10.1016/j.diabet.2016.07.029openalex-snapshot
Levels of betatrophin decrease during pregnancy despite increased insulin resistance, beta-cell function and triglyceride levels
inferred← citeshttps://doi.org/10.1016/j.diabet.2019.05.005openalex-snapshot
Regulation of hepatokine gene expression in response to fasting and feeding: Influence of PPAR-α and insulin-dependent signalling in hepatocytes
inferred← citeshttps://doi.org/10.1016/j.diabres.2015.04.028openalex-snapshot
Relationship of betatrophin with youth onset type 2 diabetes among Asian Indians
inferred← citeshttps://doi.org/10.1016/j.diabres.2016.01.029openalex-snapshot
Lipasin, a biomarker of diabetic retinopathy
inferred← citeshttps://doi.org/10.1016/j.diabres.2016.02.008openalex-snapshot
Circulating betatrophin concentration is negatively correlated with insulin resistance in obese children and adolescents
inferred← citeshttps://doi.org/10.1016/j.diabres.2016.08.017openalex-snapshot
Increased angiopoietin-like protein 8 levels in patients with type 2 diabetes and cardiovascular disease
inferred← citeshttps://doi.org/10.1016/j.diabres.2017.08.025openalex-snapshot
Angiopoietin-like protein 8: An attractive biomarker for the evaluation of subjects with insulin resistance and related disorders
inferred← citeshttps://doi.org/10.1016/j.dsx.2018.11.016openalex-snapshot
Circulating betatrophin in relation to metabolic, inflammatory parameters, and oxidative stress in patients with type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.1016/j.dsx.2019.06.027openalex-snapshot
The implication of hepatokines in metabolic syndrome
inferred← citeshttps://doi.org/10.1016/j.ejogrb.2018.04.031openalex-snapshot
Serum betatrophin/angiopoietin-like protein 8 (ANGPTL8) levels in pregnancies affected by hyperemesis gravidarum
inferred← citeshttps://doi.org/10.1016/j.fsi.2023.108549openalex-snapshot
Molecular characterization and immune functions of lipasin in Nile tilapia (Oreochromis niloticus): Involvement in the regulation of tumor necrosis factor-α secretion
inferred← citeshttps://doi.org/10.1016/j.gene.2018.09.041openalex-snapshot
Angiopoietin-like 8 (ANGPTL8) expression is regulated by miR-143-3p in human hepatocytes
inferred← citeshttps://doi.org/10.1016/j.gene.2020.144707openalex-snapshot
ANGPTL8 enhances insulin sensitivity by directly activating insulin-mediated AKT phosphorylation
inferred← citeshttps://doi.org/10.1016/j.genrep.2021.101306openalex-snapshot
The effect of ANGPTL8 protein on proliferation and apoptosis in HepG2 hepatocellular carcinoma cell line
inferred← citeshttps://doi.org/10.1016/j.heliyon.2021.e07898openalex-snapshot
Angiopoietin-like protein 4 (ANGPTL4) is an inhibitor of endothelial lipase (EL) while the ANGPTL4/8 complex has reduced EL-inhibitory activity
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e27739openalex-snapshot
Role of the angiopoietin-like protein family in the progression of NAFLD
inferred← citeshttps://doi.org/10.1016/j.isci.2024.111292openalex-snapshot
Adipocyte Angptl8 deletion improves glucose and energy metabolism and obesity associated inflammation in mice
inferred← citeshttps://doi.org/10.1016/j.jacl.2017.12.011openalex-snapshot
High frequency of type 2 diabetes and impaired glucose tolerance in Japanese subjects with the angiopoietin-like protein 8 R59W variant
inferred← citeshttps://doi.org/10.1016/j.jbc.2021.100312openalex-snapshot
Comparison of angiopoietin-like protein 3 and 4 reveals structural and mechanistic similarities
inferred← citeshttps://doi.org/10.1016/j.jdiacomp.2019.107421openalex-snapshot
Association of serum angiopoietin-like protein 2 with elevated risk of cardiovascular diseases in subjects with type 2 diabetes
inferred← citeshttps://doi.org/10.1016/j.jksus.2024.103469openalex-snapshot
Impact of a post-lifestyle modification program in circulating angiopoietin-like proteins in Arab adolescents
inferred← citeshttps://doi.org/10.1016/j.jlr.2021.100068openalex-snapshot
ApoA5 lowers triglyceride levels via suppression of ANGPTL3/8-mediated LPL inhibition
inferred← citeshttps://doi.org/10.1016/j.jlr.2021.100112openalex-snapshot
Angiopoietin-like 3 inhibition of endothelial lipase is not modulated by angiopoietin-like 8
inferred← citeshttps://doi.org/10.1016/j.jlr.2021.100150openalex-snapshot
Role and mechanism of the action of angiopoietin-like protein ANGPTL4 in plasma lipid metabolism
inferred← citeshttps://doi.org/10.1016/j.jlr.2022.100198openalex-snapshot
An anti-ANGPTL3/8 antibody decreases circulating triglycerides by binding to a LPL-inhibitory leucine zipper-like motif
inferred← citeshttps://doi.org/10.1016/j.jlr.2022.100237openalex-snapshot
ANGPTL4 silencing via antisense oligonucleotides reduces plasma triglycerides and glucose in mice without causing lymphadenopathy
inferred← citeshttps://doi.org/10.1016/j.jlr.2022.100313openalex-snapshot
Genetic Mimicry Analysis Reveals the Specific Lipases Targeted by the ANGPTL3-ANGPTL8 Complex and ANGPTL4
inferred← citeshttps://doi.org/10.1016/j.jlr.2023.100441openalex-snapshot
Decoding the role of angiopoietin-like protein 4/8 complex–mediated plasmin generation in the regulation of LPL activity
inferred← citeshttps://doi.org/10.1016/j.jlr.2023.100495openalex-snapshot
Effects of exercise training on ANGPTL3/8 and ANGPTL4/8 and their associations with cardiometabolic traits
inferred← citeshttps://doi.org/10.1016/j.jlr.2025.100751openalex-snapshot
Multilayer regulation of postprandial triglyceride metabolism in response to acute cold exposure
inferred← citeshttps://doi.org/10.1016/j.jlr.2026.101124openalex-snapshot
Chronic high-fat diet feeding reduces the rate of postprandial triglyceride absorption independent of intestinal ANGPTL4
inferred← citeshttps://doi.org/10.1016/j.jpag.2026.05.010openalex-snapshot
Evaluation of Serum Betatrophin Levels in Normal-Weight and Overweight Adolescents with Polycystic Ovary Syndrome
inferred← citeshttps://doi.org/10.1016/j.lwt.2022.113717openalex-snapshot
Novel insight into the resilient drivers of bioaccumulation perchlorate on lipid nutrients alterations in goat milk by spatial multi-omics
inferred← citeshttps://doi.org/10.1016/j.mce.2015.07.031openalex-snapshot
AMP-activated protein kinase suppresses the expression of LXR/SREBP-1 signaling-induced ANGPTL8 in HepG2 cells
inferred← citeshttps://doi.org/10.1016/j.mce.2024.112164openalex-snapshot
Branched-chain amino acids promote occurrence and development of cardiovascular disease dependent on triglyceride metabolism via activation of the mTOR/SREBP-1/betatrophin pathway
inferred← citeshttps://doi.org/10.1016/j.metabol.2023.155709openalex-snapshot
Brown adipose tissue-derived metabolites and their role in regulating metabolism
inferred← citeshttps://doi.org/10.1016/j.molmed.2019.05.010openalex-snapshot
ANGPTL4 in Metabolic and Cardiovascular Disease
inferred← citeshttps://doi.org/10.1016/j.molmet.2013.11.004openalex-snapshot
Angptl4 serves as an endogenous inhibitor of intestinal lipid digestion
inferred← citeshttps://doi.org/10.1016/j.molmet.2017.06.014openalex-snapshot
ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase
inferred← citeshttps://doi.org/10.1016/j.molmet.2020.101033openalex-snapshot
Fasting induces ANGPTL4 and reduces LPL activity in human adipose tissue
inferred← citeshttps://doi.org/10.1016/j.molmet.2021.101238openalex-snapshot
Metabolic-associated fatty liver disease and lipoprotein metabolism
inferred← citeshttps://doi.org/10.1016/j.numecd.2022.04.006openalex-snapshot
Effect of physical activity in a weight loss program on circulating total ANGPTL8 concentrations in northern Americans with obesity: A prospective randomized controlled trial
inferred← citeshttps://doi.org/10.1016/j.nutres.2024.01.006openalex-snapshot
Eight weeks of daily cottonseed oil intake attenuates postprandial angiopoietin-like proteins 3 and 4 responses compared to olive oil in adults with hypercholesterolemia: A secondary analysis of a randomized clinical trial
inferred← citeshttps://doi.org/10.1016/j.obmed.2023.100494openalex-snapshot
The impact of gender on the relation of serum angiopoietin-like protein 8 (ANGPTL8) level with metabolic parameters in adults
inferred← citeshttps://doi.org/10.1016/j.orcp.2016.08.004openalex-snapshot
Relationship between serum betatrophin levels and the first-phase of glucose-stimulated insulin secretion
inferred← citeshttps://doi.org/10.1016/j.peptides.2018.07.001openalex-snapshot
GLP-1 receptor agonists stimulate ANGPTL8 production through the PI3K/Akt pathway in a GLP-1 receptor-dependent manner
inferred← citeshttps://doi.org/10.1016/j.phrs.2020.104653openalex-snapshot
Pharmacological aspects of ANGPTL3 and ANGPTL4 inhibitors: New therapeutic approaches for the treatment of atherogenic dyslipidemia
inferred← citeshttps://doi.org/10.1016/j.plipres.2020.101067openalex-snapshot
The multi-faces of Angptl8 in health and disease: Novel functions beyond lipoprotein lipase modulation
inferred← citeshttps://doi.org/10.1016/j.plipres.2021.101140openalex-snapshot
An updated ANGPTL3-4-8 model as a mechanism of triglyceride partitioning between fat and oxidative tissues
inferred← citeshttps://doi.org/10.1016/j.redox.2023.102613openalex-snapshot
Mitochondrial NAD kinase in health and disease
inferred← citeshttps://doi.org/10.1016/j.soard.2016.01.024openalex-snapshot
Decreased serum betatrophin levels correlate with improved fasting plasma glucose and insulin secretion capacity after Roux-en-Y gastric bypass in obese Chinese patients with type 2 diabetes: a 1-year follow-up
inferred← citeshttps://doi.org/10.1016/j.soard.2018.05.026openalex-snapshot
Biphasic changes in angiopoietin-like 8 level after laparoscopic sleeve gastrectomy and type 2 diabetes remission during a 1-year follow-up
inferred← citeshttps://doi.org/10.1016/j.tem.2020.11.005openalex-snapshot
Lipoprotein Lipase and Its Regulators: An Unfolding Story
inferred← citeshttps://doi.org/10.1016/j.tem.2024.02.016openalex-snapshot
A unified model for regulating lipoprotein lipase activity
inferred← citeshttps://doi.org/10.1016/j.trsl.2016.06.012openalex-snapshot
Angiopoietin-like protein 8 (ANGPTL8) in pregnancy: a brown adipose tissue–derived endocrine factor with a potential role in fetal growth
inferred← citeshttps://doi.org/10.1016/j.yexcr.2015.09.012openalex-snapshot
ANGPTL8/betatrophin alleviates insulin resistance via the Akt-GSK3β or Akt-FoxO1 pathway in HepG2 cells
inferred← citeshttps://doi.org/10.1016/j.ygeno.2017.06.006openalex-snapshot
Visualizing the regulatory role of Angiopoietin-like protein 8 (ANGPTL8) in glucose and lipid metabolic pathways
inferred← citeshttps://doi.org/10.1016/j.ymgme.2016.04.007openalex-snapshot
The Arg59Trp variant in ANGPTL8 (betatrophin) is associated with total and HDL-cholesterol in American Indians and Mexican Americans and differentially affects cleavage of ANGPTL3
inferred← citeshttps://doi.org/10.1021/acschembio.0c00954openalex-snapshot
The Angiopoietin-Like Protein 3 and 8 Complex Interacts with Lipoprotein Lipase and Induces LPL Cleavage
inferred← citeshttps://doi.org/10.1038/ijo.2015.206openalex-snapshot
Interplay of atherogenic factors, protein intake and betatrophin levels in obese–metabolic syndrome patients treated with hypocaloric diets
inferred← citeshttps://doi.org/10.1038/nrendo.2017.119openalex-snapshot
Angiopoietin-like 3 in lipoprotein metabolism
inferred← citeshttps://doi.org/10.1038/s41419-022-05029-8openalex-snapshot
ANGPTL8 is a negative regulator in pathological cardiac hypertrophy
inferred← citeshttps://doi.org/10.1038/s41467-019-11513-1openalex-snapshot
Angptl8 mediates food-driven resetting of hepatic circadian clock in mice
inferred← citeshttps://doi.org/10.1038/s41467-023-40183-3openalex-snapshot
LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis
inferred← citeshttps://doi.org/10.1038/s41588-020-00766-yopenalex-snapshot
Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost power
inferred← citeshttps://doi.org/10.1038/s41588-021-01011-wopenalex-snapshot
Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank
inferred← citeshttps://doi.org/10.1038/s41598-017-03538-7openalex-snapshot
Circulating angiopoietin-like 8 (ANGPTL8) is a marker of liver steatosis and is negatively regulated by Prader-Willi Syndrome
inferred← citeshttps://doi.org/10.1038/s41598-017-11750-8openalex-snapshot
A New Tactic for Label-Free Recognition of β-Trophin via Electrochemiluminescent Signalling on an AuNPs Supported Immuno-Interface
inferred← citeshttps://doi.org/10.1038/s41598-020-63850-7openalex-snapshot
Association of ANGPTL8 (Betatrophin) Gene Variants with Components of Metabolic Syndrome in Arab Adults
inferred← citeshttps://doi.org/10.1038/s41598-020-66570-0openalex-snapshot
Transcriptional Regulation of the Angptl8 Gene by Hepatocyte Nuclear Factor-1 in the Murine Liver
inferred← citeshttps://doi.org/10.1038/s41598-020-69091-yopenalex-snapshot
The circulating ANGPTL8 levels show differences among novel subgroups of adult patients with diabetes and are associated with mortality in the subsequent 5 years
inferred← citeshttps://doi.org/10.1038/s41598-020-70075-1openalex-snapshot
Betatrophin is downregulated in pregnant women with a history of RYGB operation and a high risk of postprandial hypoglycaemia
inferred← citeshttps://doi.org/10.1038/srep05013openalex-snapshot
Elevated circulating lipasin/betatrophin in human type 2 diabetes and obesity
inferred← citeshttps://doi.org/10.1038/srep18502openalex-snapshot
A lipasin/Angptl8 monoclonal antibody lowers mouse serum triglycerides involving increased postprandial activity of the cardiac lipoprotein lipase
inferred← citeshttps://doi.org/10.1038/srep24013openalex-snapshot
Association between betatrophin/ANGPTL8 and non-alcoholic fatty liver disease: animal and human studies
inferred← citeshttps://doi.org/10.1038/srep28431openalex-snapshot
The Effects of Serum ANGPTL8/betatrophin on the Risk of Developing the Metabolic Syndrome – A Prospective Study
inferred← citeshttps://doi.org/10.1038/srep36926openalex-snapshot
Fasting and Feeding Signals Control the Oscillatory Expression of Angptl8 to Modulate Lipid Metabolism
inferred← citeshttps://doi.org/10.1042/cs20230031openalex-snapshot
ANGPTL8 deletion attenuates abdominal aortic aneurysm formation in ApoE−/− mice
inferred← citeshttps://doi.org/10.1049/iet-syb.2019.0032openalex-snapshot
Deciphering the expression dynamics of ANGPTL8 associated regulatory network in insulin resistance using formal modelling approaches
inferred← citeshttps://doi.org/10.1055/s-0043-102950openalex-snapshot
ANGPTL8 (Betatrophin) is Expressed in Visceral Adipose Tissue and Relates to Human Hepatic Steatosis in Two Independent Clinical Collectives
inferred← citeshttps://doi.org/10.1055/s-0043-108911openalex-snapshot
The Correlation Between Circulating Betatrophin and Insulin Resistance in General Population: A Meta-Analysis
inferred← citeshttps://doi.org/10.1063/5.0002471openalex-snapshot
Computational study of betatrophin/ANGPTL8 and HBV interaction on lipoprotein lipase activity in the development of hepatocellular carcinoma caused by metabolic syndrome-related HBV infection
inferred← citeshttps://doi.org/10.1073/pnas.1217552109openalex-snapshot
Atypical angiopoietin-like protein that regulates ANGPTL3
inferred← citeshttps://doi.org/10.1073/pnas.1315292110openalex-snapshot
Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis
inferred← citeshttps://doi.org/10.1073/pnas.1513872112openalex-snapshot
Angptl4 links α-cell proliferation following glucagon receptor inhibition with adipose tissue triglyceride metabolism
inferred← citeshttps://doi.org/10.1073/pnas.1515374112openalex-snapshot
Hepatic ANGPTL3 regulates adipose tissue energy homeostasis
inferred← citeshttps://doi.org/10.1073/pnas.1717420115openalex-snapshot
Increased thermogenesis by a noncanonical pathway in ANGPTL3/8-deficient mice
inferred← citeshttps://doi.org/10.1080/01443615.2017.1286464openalex-snapshot
Assessment of circulating betatrophin concentrations in lean glucose-tolerant women with polycystic ovary syndrome
inferred← citeshttps://doi.org/10.1080/09513590.2018.1519791openalex-snapshot
Serum betatrophin levels are reduced in patients with full-blown polycystic ovary syndrome
inferred← citeshttps://doi.org/10.1080/09513590.2018.1536736openalex-snapshot
Circulating Angiopoietin-like 8 protein (ANGPTL8/Betatrophin) in patients with polycystic ovary syndrome: a systematic review and multi effect size meta-analysis
inferred← citeshttps://doi.org/10.1080/09513590.2020.1725964openalex-snapshot
Serum betatrophin levels are significantly increased in obese patients compared to lean patients regardless to the presence of PCOS
inferred← citeshttps://doi.org/10.1080/09674845.2020.1764211openalex-snapshot
Circulating micro RNA-223 and angiopoietin-like protein 8 as biomarkers of gestational diabetes mellitus
inferred← citeshttps://doi.org/10.1080/13813455.2020.1849310openalex-snapshot
The effect of 4-week endurance training on serum levels of irisin and betatrophin in streptozotocin- induced diabetic rats
inferred← citeshttps://doi.org/10.1080/14728222.2020.1707806openalex-snapshot
Angiopoietin-like proteins as therapeutic targets for cardiovascular disease: focus on lipid disorders
inferred← citeshttps://doi.org/10.1080/14767058.2018.1481382openalex-snapshot
Assessment of circulating betatrophin levels in intrahepatic cholestasis of pregnancy
inferred← citeshttps://doi.org/10.1088/1742-6596/1146/1/012003openalex-snapshot
The potential role of betatrophin in hepatocellular carcinoma and metabolic syndrome
inferred← citeshttps://doi.org/10.1093/bbb/zbac043openalex-snapshot
Royal jelly fatty acids downregulate ANGPTL8 expression through the decrease in HNF4α protein in human hepatoma HepG2 cells
inferred← citeshttps://doi.org/10.1093/jas/sky162openalex-snapshot
Downregulated angiopoietin-like protein 8 production at calving related to changes in lipid metabolism in dairy cows
inferred← citeshttps://doi.org/10.1097/fjc.0000000000001132openalex-snapshot
Human Angiopoietin-like Protein 3/ANGPTL3 Antibodies: Adding to the Armamentarium in the Management of Dyslipidemia
inferred← citeshttps://doi.org/10.1097/md.0000000000025646openalex-snapshot
Association of betatrophin amounts with 25-(OH)D levels in patients with gestational diabetes mellitus
inferred← citeshttps://doi.org/10.1097/mol.0000000000000290openalex-snapshot
Regulation of lipid metabolism by angiopoietin-like proteins
inferred← citeshttps://doi.org/10.1097/mol.0000000000000798openalex-snapshot
Angiopoietin-like proteins and postprandial partitioning of fatty acids
inferred← citeshttps://doi.org/10.1097/mol.0000000000000910openalex-snapshot
Angiopoietin-like protein 8: a multifaceted protein instrumental in regulating triglyceride metabolism
inferred← citeshttps://doi.org/10.1097/mol.0b013e3283630cf0openalex-snapshot
The angiopoietin-like protein 3
inferred← citeshttps://doi.org/10.1097/mop.0000000000000110openalex-snapshot
Role of growth factors in control of pancreatic beta cell mass
inferred← citeshttps://doi.org/10.1098/rsob.150272openalex-snapshot
The ANGPTL3-4-8 model, a molecular mechanism for triglyceride trafficking
inferred← citeshttps://doi.org/10.1098/rsob.210106openalex-snapshot
ANGPTL8 in metabolic homeostasis: more friend than foe?
inferred← citeshttps://doi.org/10.1101/140590openalex-snapshot
Differential associations of various depression-related phenotypes with cardiometabolic risks: Identification of shared genetic factors and implications for drug repositioning
inferred← citeshttps://doi.org/10.1101/2023.07.04.547624openalex-snapshot
ANGPTL8 R59W variant influences inflammation through modulating NF-κB pathway under TNFα stimulation
inferred← citeshttps://doi.org/10.1111/dme.12696openalex-snapshot
Correlation of circulating betatrophin concentrations with insulin secretion capacity, evaluated by glucagon stimulation tests
inferred← citeshttps://doi.org/10.1111/jdi.12792openalex-snapshot
Angiopoietin‐like protein 8/betatrophin correlates with hepatocellular lipid content independent of insulin resistance in non‐alcoholic fatty liver disease patients
inferred← citeshttps://doi.org/10.1111/jphp.13342openalex-snapshot
HWL-088, a new and highly effective FFA1/PPARδ dual agonist, attenuates nonalcoholic steatohepatitis by regulating lipid metabolism, inflammation and fibrosis
inferred← citeshttps://doi.org/10.1111/pedi.12233openalex-snapshot
Characterisation of betatrophin concentrations in childhood and adolescent obesity and insulin resistance
inferred← citeshttps://doi.org/10.1111/pedi.12412openalex-snapshot
Betatrophin: no relation to glucose metabolism or weight status in obese children before and after lifestyle intervention
inferred← citeshttps://doi.org/10.1111/rda.13244openalex-snapshot
Tissue expression and variation analysis of three bovine adipokine genes revealed their effect on growth traits in native Chinese cattle
inferred← citeshttps://doi.org/10.1152/ajpendo.00195.2021openalex-snapshot
Regulation of lipoprotein metabolism by ANGPTL3, ANGPTL4, and ANGPTL8
inferred← citeshttps://doi.org/10.1152/physiolgenomics.00083.2020openalex-snapshot
Transcriptomic signature of fasting in human adipose tissue
inferred← citeshttps://doi.org/10.1155/2014/323407openalex-snapshot
Increased Circulating Betatrophin Concentrations in Patients with Type 2 Diabetes
inferred← citeshttps://doi.org/10.1155/2014/873679openalex-snapshot
Role of Ink4a/Arf Locus in Beta Cell Mass Expansion under Physiological and Pathological Conditions
inferred← citeshttps://doi.org/10.1155/2015/479157openalex-snapshot
Betatrophin Acts as a Diagnostic Biomarker in Type 2 Diabetes Mellitus and Is Negatively Associated with HDL-Cholesterol
inferred← citeshttps://doi.org/10.1155/2016/2616539openalex-snapshot
Circulating Levels of Betatrophin and Irisin Are Not Associated with Pancreaticβ-Cell Function in Previously Diagnosed Type 2 Diabetes Mellitus Patients
inferred← citeshttps://doi.org/10.1155/2016/4860595openalex-snapshot
The Rise and the Fall of Betatrophin/ANGPTL8 as an Inducer ofβ-Cell Proliferation
inferred← citeshttps://doi.org/10.1155/2016/5090852openalex-snapshot
Circulating Betatrophin Is Increased in Patients with Overt and Subclinical Hypothyroidism
inferred← citeshttps://doi.org/10.1155/2016/6194750openalex-snapshot
Circulating Betatrophin in Patients with Type 2 Diabetes: A Meta-Analysis
inferred← citeshttps://doi.org/10.1155/2016/9391837openalex-snapshot
The Relationship between Betatrophin Levels in Blood and T2DM: A Systematic Review and Meta-Analysis
inferred← citeshttps://doi.org/10.1155/2017/2316986openalex-snapshot
Serum Concentrations of Betatrophin and Its Association with Indirect Indices of Insulin Resistance and Beta Cell Function in Women with Polycystic Ovary Syndrome
inferred← citeshttps://doi.org/10.1155/2017/8187235openalex-snapshot
Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway
inferred← citeshttps://doi.org/10.1155/2017/8293207openalex-snapshot
Increased Serum ANGPTL8 Concentrations in Patients with Prediabetes and Type 2 Diabetes
inferred← citeshttps://doi.org/10.1155/2019/6321427openalex-snapshot
Circulating ANGPTL8 Is Associated with the Presence of Metabolic Syndrome and Insulin Resistance in Polycystic Ovary Syndrome Young Women
inferred← citeshttps://doi.org/10.1155/2020/1253164openalex-snapshot
Adipose Insulin Resistance and Circulating Betatrophin Levels in Women with PCOS
inferred← citeshttps://doi.org/10.1155/2020/1621239openalex-snapshot
The ANGPTL8 rs2278426 (C/T) Polymorphism Is Associated with Prediabetes and Type 2 Diabetes in a Han Chinese Population in Hebei Province
inferred← citeshttps://doi.org/10.1155/2021/6699923openalex-snapshot
Effect of Ileal Transposition (IT) on Angiopoietin-Like Protein-8 (ANGPTL8) and Pentraxin (PTX3) Plasma Level in Sprague-Dawley Rats Fed High-Fat Diet (HFD)
inferred← citeshttps://doi.org/10.1161/atvbaha.124.321308openalex-snapshot
Circulating ANGPTL3/8 Concentrations Are Associated With an Atherogenic Lipoprotein Profile and Increased CHD Risk in Swedish Population-Based Studies
inferred← citeshttps://doi.org/10.1161/circulationaha.126.080412openalex-snapshot
Dual Control of Low-Density Lipoprotein Cholesterol Levels by ANGPTL3 and ANGPTL8
inferred← citeshttps://doi.org/10.1172/jci.insight.138777openalex-snapshot
ANGPTL8 has both endocrine and autocrine effects on substrate utilization
inferred← citeshttps://doi.org/10.1172/jci.insight.181553openalex-snapshot
Postprandial exercise regulates tissue-specific triglyceride uptake through angiopoietin-like proteins
inferred← citeshttps://doi.org/10.1172/jci.insight.197827openalex-snapshot
Angiopoietin-like 3 monomers are abundant in human plasma but are unable to inhibit endothelial lipase
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